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Conserved domains on  [gi|2462561429|ref|XP_054175069|]
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zinc finger protein 236 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
195-705 2.05e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.02  E-value: 2.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  195 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 272
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  273 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPQNSTSSTETAHVLTATLFQ-TLPLQQTEAQATSA 345
Cdd:COG5048    104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHpPLPANSLSKDPSSN 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  346 SSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSitvgiNQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQ 425
Cdd:COG5048    184 LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLE-----NSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  426 NPDVSSVSNEQTdptdaeqekeqespekldkkekkmiKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHT 505
Cdd:COG5048    259 ESPRSSLPTASS-------------------------QSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  506 HE----KPFKCPQcfrafavkstltahikthtgikafkcQYCMKSFSTSGSLKVHIRLHTGVRPFACP--HCDKKFrtsg 579
Cdd:COG5048    314 HSgeslKPFSCPY--------------------------SLCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKF---- 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  580 hrkthiaSHFKHTELRKMRHQRKpakvrvgktnvpvpdIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKC 659
Cdd:COG5048    364 -------SPLLNNEPPQSLQQYK---------------DLKNDKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKN 421

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561429  660 FYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRgFVSAGVLKAHIR 705
Cdd:COG5048    422 PPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1337-1613 7.46e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.85  E-value: 7.46e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1337 ASVSAGGDLTVSL--TDGSLaTLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPG 1414
Cdd:COG3210    802 GTITAAGTTAINVtgSGGTI-TINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVG 880

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1415 LAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEIT 1494
Cdd:COG3210    881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1495 LTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADT 1574
Cdd:COG3210    961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATA 1040

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2462561429 1575 QGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGS 1613
Cdd:COG3210   1041 GGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGG 1079
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
13-232 1.13e-06

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429   13 HHDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHK--CTHSG 90
Cdd:COG5048    237 PKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLrsVNHSG 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429   91 EDPT---CPV--CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTlqsqlavHMEEHRQELAGTRQHACKACK-KEFET 164
Cdd:COG5048    317 ESLKpfsCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSK-------FSPLLNNEPPQSLQQYKDLKNdKKSET 389

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462561429  165 S-SELKEHMKTHYKIRVSSTRSYNRNIDRsgftYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGK 232
Cdd:COG5048    390 LsNSCIRNFKRDSNLSLHIITHLSFRPYN----CKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
951-1313 2.85e-06

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.01  E-value: 2.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  951 QGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH---EKTHTGVKAFSCSV 1027
Cdd:COG5048     18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSrhlRTHHNNPSDLNSKS 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1028 CNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTV--------HCKKHMKRHQTV-------PSAVSATGETEGGDIC 1092
Cdd:COG5048     98 LPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDpqlpdllsISNLRNNPLPGNnsssvntPQSNSLHPPLPANSLS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1093 MEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV-QSAAEKDRISELRDKQAELQDEPKHANcCTY 1171
Cdd:COG5048    178 KDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSsLPLTTNSQLSPKSLLSQSPSSLSSSDS-SSS 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1172 CPKSFKKPSDLVRHVRIH----------TGEKPYKCDECGKSFTVKSTLDCHVKT--HTGQKL--FSCHV--CSNAFSTK 1235
Cdd:COG5048    257 ASESPRSSLPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRSvnHSGESLkpFSCPYslCGKLFSRN 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1236 GSLKVHMRLHTGAKPFKCP--HCELRFRTSGRRKTHMQFHYKPDPKKARKPMTrsSSEGLQPVNLLNSSSTDPNVFIMNN 1313
Cdd:COG5048    337 DALKRHILLHTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKNDKKSET--LSNSCIRNFKRDSNLSLHIITHLSF 414
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1737-1761 3.22e-05

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.36  E-value: 3.22e-05
                           10        20
                   ....*....|....*....|....*
gi 2462561429 1737 LERHSRIHTGERPFHCTLCEKAFNQ 1761
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
651-1055 7.28e-05

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.38  E-value: 7.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  651 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHIRTHTGLKSFKCLICNG-AFTTGGS 727
Cdd:COG5048     28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  728 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTvdqqsmqASTQMQVEIESDELPQ 807
Cdd:COG5048    108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQS-------NSLHPPLPANSLSKDP 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  808 TAEVVAANPEAMLDLEPQHvvgtEEAGLGQQLADQPLEADEDGFVAPQDPL-RGHVDQFEEQSPAQQSfepaglPQGFTV 886
Cdd:COG5048    181 SSNLSLLISSNVSTSIPSS----SENSPLSSSYSIPSSSSDQNLENSSSSLpLTTNSQLSPKSLLSQS------PSSLSS 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  887 TDTYHQQPQFPPVQQLQDSSTLESQALS-TSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLqaqgsqflEDNEDQSRR 965
Cdd:COG5048    251 SDSSSSASESPRSSLPTASSQSSSPNESdSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN--------HSGESLKPF 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  966 SYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKS-------HEKTHTGVKAFSCSV--CNASFTTNG 1036
Cdd:COG5048    323 SCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDS 402

                          410
                   ....*....|....*....
gi 2462561429 1037 SLTRHMATHMSMKPYKCPF 1055
Cdd:COG5048    403 NLSLHIITHLSFRPYNCKN 421
SUF4-like super family cl41227
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1659-1707 4.72e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


The actual alignment was detected with superfamily member cd20908:

Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.62  E-value: 4.72e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2462561429 1659 CLECDRAFSSAAVLMHHSKEVHGRerihgCPVCRKAFKRATHLKEHMQT 1707
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1764-1789 5.49e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 5.49e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561429 1764 ALQVHMKKHTGERPYKCAYCVMGFTQ 1789
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
195-705 2.05e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.02  E-value: 2.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  195 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 272
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  273 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPQNSTSSTETAHVLTATLFQ-TLPLQQTEAQATSA 345
Cdd:COG5048    104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHpPLPANSLSKDPSSN 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  346 SSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSitvgiNQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQ 425
Cdd:COG5048    184 LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLE-----NSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  426 NPDVSSVSNEQTdptdaeqekeqespekldkkekkmiKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHT 505
Cdd:COG5048    259 ESPRSSLPTASS-------------------------QSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  506 HE----KPFKCPQcfrafavkstltahikthtgikafkcQYCMKSFSTSGSLKVHIRLHTGVRPFACP--HCDKKFrtsg 579
Cdd:COG5048    314 HSgeslKPFSCPY--------------------------SLCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKF---- 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  580 hrkthiaSHFKHTELRKMRHQRKpakvrvgktnvpvpdIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKC 659
Cdd:COG5048    364 -------SPLLNNEPPQSLQQYK---------------DLKNDKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKN 421

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561429  660 FYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRgFVSAGVLKAHIR 705
Cdd:COG5048    422 PPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1337-1613 7.46e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.85  E-value: 7.46e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1337 ASVSAGGDLTVSL--TDGSLaTLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPG 1414
Cdd:COG3210    802 GTITAAGTTAINVtgSGGTI-TINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVG 880

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1415 LAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEIT 1494
Cdd:COG3210    881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1495 LTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADT 1574
Cdd:COG3210    961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATA 1040

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2462561429 1575 QGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGS 1613
Cdd:COG3210   1041 GGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGG 1079
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
13-232 1.13e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429   13 HHDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHK--CTHSG 90
Cdd:COG5048    237 PKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLrsVNHSG 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429   91 EDPT---CPV--CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTlqsqlavHMEEHRQELAGTRQHACKACK-KEFET 164
Cdd:COG5048    317 ESLKpfsCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSK-------FSPLLNNEPPQSLQQYKDLKNdKKSET 389

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462561429  165 S-SELKEHMKTHYKIRVSSTRSYNRNIDRsgftYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGK 232
Cdd:COG5048    390 LsNSCIRNFKRDSNLSLHIITHLSFRPYN----CKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
951-1313 2.85e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.01  E-value: 2.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  951 QGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH---EKTHTGVKAFSCSV 1027
Cdd:COG5048     18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSrhlRTHHNNPSDLNSKS 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1028 CNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTV--------HCKKHMKRHQTV-------PSAVSATGETEGGDIC 1092
Cdd:COG5048     98 LPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDpqlpdllsISNLRNNPLPGNnsssvntPQSNSLHPPLPANSLS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1093 MEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV-QSAAEKDRISELRDKQAELQDEPKHANcCTY 1171
Cdd:COG5048    178 KDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSsLPLTTNSQLSPKSLLSQSPSSLSSSDS-SSS 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1172 CPKSFKKPSDLVRHVRIH----------TGEKPYKCDECGKSFTVKSTLDCHVKT--HTGQKL--FSCHV--CSNAFSTK 1235
Cdd:COG5048    257 ASESPRSSLPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRSvnHSGESLkpFSCPYslCGKLFSRN 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1236 GSLKVHMRLHTGAKPFKCP--HCELRFRTSGRRKTHMQFHYKPDPKKARKPMTrsSSEGLQPVNLLNSSSTDPNVFIMNN 1313
Cdd:COG5048    337 DALKRHILLHTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKNDKKSET--LSNSCIRNFKRDSNLSLHIITHLSF 414
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1181-1205 3.59e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.05  E-value: 3.59e-06
                           10        20
                   ....*....|....*....|....*
gi 2462561429 1181 DLVRHVRIHTGEKPYKCDECGKSFT 1205
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
212-236 9.11e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 9.11e-06
                           10        20
                   ....*....|....*....|....*
gi 2462561429  212 LTRHIRIHTGERPFKCSECGKAFNQ 236
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1737-1761 3.22e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.36  E-value: 3.22e-05
                           10        20
                   ....*....|....*....|....*
gi 2462561429 1737 LERHSRIHTGERPFHCTLCEKAFNQ 1761
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
651-1055 7.28e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.38  E-value: 7.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  651 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHIRTHTGLKSFKCLICNG-AFTTGGS 727
Cdd:COG5048     28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  728 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTvdqqsmqASTQMQVEIESDELPQ 807
Cdd:COG5048    108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQS-------NSLHPPLPANSLSKDP 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  808 TAEVVAANPEAMLDLEPQHvvgtEEAGLGQQLADQPLEADEDGFVAPQDPL-RGHVDQFEEQSPAQQSfepaglPQGFTV 886
Cdd:COG5048    181 SSNLSLLISSNVSTSIPSS----SENSPLSSSYSIPSSSSDQNLENSSSSLpLTTNSQLSPKSLLSQS------PSSLSS 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  887 TDTYHQQPQFPPVQQLQDSSTLESQALS-TSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLqaqgsqflEDNEDQSRR 965
Cdd:COG5048    251 SDSSSSASESPRSSLPTASSQSSSPNESdSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN--------HSGESLKPF 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  966 SYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKS-------HEKTHTGVKAFSCSV--CNASFTTNG 1036
Cdd:COG5048    323 SCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDS 402

                          410
                   ....*....|....*....
gi 2462561429 1037 SLTRHMATHMSMKPYKCPF 1055
Cdd:COG5048    403 NLSLHIITHLSFRPYNCKN 421
auto_AIDA-I NF033176
autotransporter adhesin AIDA-I;
1393-1595 4.58e-04

autotransporter adhesin AIDA-I;


Pssm-ID: 380183 [Multi-domain]  Cd Length: 1287  Bit Score: 45.42  E-value: 4.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1393 SILQQTLQQGNLLAQQLTGEPG--LAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSG 1470
Cdd:NF033176     6 SIVWNHSRQAWVVASELARGHGfvLAKNTLLVLAVASTIGNAFAQNISSGVVSGGVVSSGETQVVYSNGQTSNATVNSGG 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1471 TQDLTqvmtsqglvspSGGPHEITlTINNSSLSQVLAQAAGPTATSSSGSPQEItltiselntTSGSLPSTTPMSPSAIS 1550
Cdd:NF033176    86 IQNVN-----------NGGKTTST-TVNSSGAQNVGNSGTAISTIVNSGGVQRV---------SSGGVTSATSLSGGAQN 144

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561429 1551 TQNLvmsssgvgGDASVTLTL-ADTQGMLSGGLDTVTlNITSQGQQ 1595
Cdd:NF033176   145 IYNL--------GHASNTVIFnGGNQTIFSGGISDDT-NISSGGQQ 181
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1659-1707 4.72e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.62  E-value: 4.72e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2462561429 1659 CLECDRAFSSAAVLMHHSKEVHGRerihgCPVCRKAFKRATHLKEHMQT 1707
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1764-1789 5.49e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 5.49e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561429 1764 ALQVHMKKHTGERPYKCAYCVMGFTQ 1789
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 683-732 6.21e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.23  E-value: 6.21e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462561429  683 KPFkCSQCGRGFVSAGVLKAHIRTHTglksFKCLICNGAFTTGGSLRRHM 732
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 969-1013 1.03e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.46  E-value: 1.03e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 2462561429  969 CDYCNKGFKKSSHLKQHVRSHTgekpYKCKLCGRGFVSSGVLKSH 1013
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 199-244 2.20e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 2.20e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561429  199 CPHCGKTFQKPSQLTRHIRIHTgerpFKCSECGKAFNQKGALQTHM 244
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-H2C2_2 pfam13465
Zinc-finger double domain;
727-752 5.41e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 5.41e-03
                           10        20
                   ....*....|....*....|....*.
gi 2462561429  727 SLRRHMGIHNDLRPYMCPYCQKTFKT 752
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SP3_N cd22537
N-terminal domain of transcription factor Specificity Protein (SP) 3; Specificity Proteins ...
 1288-1573 7.65e-03

N-terminal domain of transcription factor Specificity Protein (SP) 3; Specificity Proteins (SPs) are transcription factors that are involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. SP1 and SP3 can interact with and recruit a large number of proteins including the transcription initiation complex, histone modifying enzymes, and chromatin remodeling complexes, which strongly suggest that SP1 and SP3 are important transcription factors in remodeling chromatin and the regulation of gene expression. SP3 belongs to a family of proteins, called the SP/Kruppel or Krueppel-like Factor (KLF) family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. SP factors preferentially bind GC boxes, while KLFs bind CACCC boxes. Another characteristic hallmark of SP factors is the presence of the Buttonhead (BTD) box CXCPXC, just N-terminal to the zinc fingers. The function of the BTD box is unknown, but it is thought to play an important physiological role. Another feature of most SP factors is the presence of a conserved amino acid stretch, the so-called SP box, located close to the N-terminus. SP factors may be separated into three groups based on their domain architecture and the similarity of their N-terminal transactivation domains: SP1-4, SP5, and SP6-9. The transactivation domains between the three groups are not homologous to one another. SP1-4 have similar N-terminal transactivation domains characterized by glutamine-rich regions, which, in most cases, have adjacent serine/threonine-rich regions. This model represents the N-terminal domain of SP3.


Pssm-ID: 411774 [Multi-domain]  Cd Length: 574  Bit Score: 41.09  E-value: 7.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1288 SSSEGLQPVNLLNSSSTDPNVFIMNNSvlTGQFDQNLLQPGLVGQAILPASVSAGG----DLTVSLTDGSLATLEGIQLQ 1363
Cdd:cd22537    259 NSGESGKVSPDINETNTNADLFVPTSS--SSQLPVTIDSTGILQQNASSLTTVSGQvhtsDLQGNYIQAPVSDETQAQNI 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1364 LAANLVGPNVQISGIDAASinnitlQIDPSILQQTLQQGNLLAQQLTGE---PGLAPQNSSLQTSDstvPASVVIQpisg 1440
Cdd:cd22537    337 QVSTAQPSVQQIQLHESQQ------PTSQAQIVQGITQQAIQGVQALGAqaiPQQALQNLQLQLLN---PGTFLIQ---- 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1441 lslQPTVTSanltigplSEQDSVLTTNSSGTQDLtqvmtsQGLVSPSGGPHEITLT-INNSSLSQVLAQAAG---PTATS 1516
Cdd:cd22537    404 ---AQTVTP--------SGQITWQTFQVQGVQNL------QNLQIQNAPAQQITLTpVQTLTLGQVGAGGAItstPVSLS 466

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462561429 1517 SSGSPQEITLTISELNTTSGSL-PSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLAD 1573
Cdd:cd22537    467 TGQLPNLQTVTVNSIDSAGIQLqQSENADSPADIQIKEEEPDSEEWQLSGDSTLNTND 524
PHA00733 PHA00733
hypothetical protein
 535-585 8.17e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.32  E-value: 8.17e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462561429  535 IKAFKCQYCMKSFSTSGSLKVHIRL--HTGVrpfaCPHCDKKFRTSGHRKTHI 585
Cdd:PHA00733    71 VSPYVCPLCLMPFSSSVSLKQHIRYteHSKV----CPVCGKEFRNTDSTLDHV 119
PHA00733 PHA00733
hypothetical protein
 94-140 8.82e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.32  E-value: 8.82e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2462561429   94 TCPVCNKKFSRVASLKAHImlHEKEENLICSECGDEFTLQSQLAVHM 140
Cdd:PHA00733    75 VCPLCLMPFSSSVSLKQHI--RYTEHSKVCPVCGKEFRNTDSTLDHV 119
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
195-705 2.05e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.02  E-value: 2.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  195 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 272
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  273 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPQNSTSSTETAHVLTATLFQ-TLPLQQTEAQATSA 345
Cdd:COG5048    104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHpPLPANSLSKDPSSN 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  346 SSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSitvgiNQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQ 425
Cdd:COG5048    184 LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLE-----NSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  426 NPDVSSVSNEQTdptdaeqekeqespekldkkekkmiKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHT 505
Cdd:COG5048    259 ESPRSSLPTASS-------------------------QSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  506 HE----KPFKCPQcfrafavkstltahikthtgikafkcQYCMKSFSTSGSLKVHIRLHTGVRPFACP--HCDKKFrtsg 579
Cdd:COG5048    314 HSgeslKPFSCPY--------------------------SLCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKF---- 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  580 hrkthiaSHFKHTELRKMRHQRKpakvrvgktnvpvpdIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKC 659
Cdd:COG5048    364 -------SPLLNNEPPQSLQQYK---------------DLKNDKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKN 421

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561429  660 FYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRgFVSAGVLKAHIR 705
Cdd:COG5048    422 PPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1337-1613 7.46e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.85  E-value: 7.46e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1337 ASVSAGGDLTVSL--TDGSLaTLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPG 1414
Cdd:COG3210    802 GTITAAGTTAINVtgSGGTI-TINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVG 880

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1415 LAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEIT 1494
Cdd:COG3210    881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1495 LTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADT 1574
Cdd:COG3210    961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATA 1040

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2462561429 1575 QGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGS 1613
Cdd:COG3210   1041 GGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGG 1079
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1297-1649 2.25e-07

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 56.31  E-value: 2.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1297 NLLNSSSTDPNVFIMNNSVLTGQFDQNLLQ--PGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQLAANLVGPNVQ 1374
Cdd:COG3210    639 VGAALSGTGSGTTGTASANGSNTTGVNTAGgtGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGSITVTGQ 718

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1375 ISGIDAASINNITLQIDPSILQQTLQQGNLLAqqlTGEPGlapqNSSLQTSDSTVpasvviqpISGLSLQPTVTSANLTI 1454
Cdd:COG3210    719 IGALANANGDTVTFGNLGTGATLTLNAGVTIT---SGNAG----TLSIGLTANTT--------ASGTTLTLANANGNTSA 783

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1455 GplseqdsvlTTNSSGTQDLTQVMTSQGLVSpSGGPHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTT 1534
Cdd:COG3210    784 G---------ATLDNAGAEISIDITADGTIT-AAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTT 853

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1535 SGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVT--LTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAG 1612
Cdd:COG3210    854 SDGASGGGTAGANSGSLAATAASITVGSGGVATStgTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAA 933

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 2462561429 1613 SPQVILVSHTPQSASAaceeIAYQVAGVSGNLAPGNQ 1649
Cdd:COG3210    934 GGTGAGNGTTALSGTQ----GNAGLSAASASDGAGDT 966
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
13-232 1.13e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429   13 HHDPDGVLTLNAENTNYAYQVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHK--CTHSG 90
Cdd:COG5048    237 PKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLrsVNHSG 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429   91 EDPT---CPV--CNKKFSRVASLKAHIMLHEKEENLICSECGDEFTlqsqlavHMEEHRQELAGTRQHACKACK-KEFET 164
Cdd:COG5048    317 ESLKpfsCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSK-------FSPLLNNEPPQSLQQYKDLKNdKKSET 389

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462561429  165 S-SELKEHMKTHYKIRVSSTRSYNRNIDRsgftYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGK 232
Cdd:COG5048    390 LsNSCIRNFKRDSNLSLHIITHLSFRPYN----CKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
951-1313 2.85e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.01  E-value: 2.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  951 QGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH---EKTHTGVKAFSCSV 1027
Cdd:COG5048     18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSrhlRTHHNNPSDLNSKS 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1028 CNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTV--------HCKKHMKRHQTV-------PSAVSATGETEGGDIC 1092
Cdd:COG5048     98 LPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDpqlpdllsISNLRNNPLPGNnsssvntPQSNSLHPPLPANSLS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1093 MEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV-QSAAEKDRISELRDKQAELQDEPKHANcCTY 1171
Cdd:COG5048    178 KDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSsLPLTTNSQLSPKSLLSQSPSSLSSSDS-SSS 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1172 CPKSFKKPSDLVRHVRIH----------TGEKPYKCDECGKSFTVKSTLDCHVKT--HTGQKL--FSCHV--CSNAFSTK 1235
Cdd:COG5048    257 ASESPRSSLPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRSvnHSGESLkpFSCPYslCGKLFSRN 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1236 GSLKVHMRLHTGAKPFKCP--HCELRFRTSGRRKTHMQFHYKPDPKKARKPMTrsSSEGLQPVNLLNSSSTDPNVFIMNN 1313
Cdd:COG5048    337 DALKRHILLHTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKNDKKSET--LSNSCIRNFKRDSNLSLHIITHLSF 414
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1181-1205 3.59e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.05  E-value: 3.59e-06
                           10        20
                   ....*....|....*....|....*
gi 2462561429 1181 DLVRHVRIHTGEKPYKCDECGKSFT 1205
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
212-236 9.11e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 9.11e-06
                           10        20
                   ....*....|....*....|....*
gi 2462561429  212 LTRHIRIHTGERPFKCSECGKAFNQ 236
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
671-696 2.31e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 2.31e-05
                           10        20
                   ....*....|....*....|....*.
gi 2462561429  671 HLKQHIRSHTGEKPFKCSQCGRGFVS 696
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
981-1006 2.45e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 2.45e-05
                           10        20
                   ....*....|....*....|....*.
gi 2462561429  981 HLKQHVRSHTGEKPYKCKLCGRGFVS 1006
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1737-1761 3.22e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.36  E-value: 3.22e-05
                           10        20
                   ....*....|....*....|....*
gi 2462561429 1737 LERHSRIHTGERPFHCTLCEKAFNQ 1761
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
651-1055 7.28e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.38  E-value: 7.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  651 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHIRTHTGLKSFKCLICNG-AFTTGGS 727
Cdd:COG5048     28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  728 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTvdqqsmqASTQMQVEIESDELPQ 807
Cdd:COG5048    108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQS-------NSLHPPLPANSLSKDP 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  808 TAEVVAANPEAMLDLEPQHvvgtEEAGLGQQLADQPLEADEDGFVAPQDPL-RGHVDQFEEQSPAQQSfepaglPQGFTV 886
Cdd:COG5048    181 SSNLSLLISSNVSTSIPSS----SENSPLSSSYSIPSSSSDQNLENSSSSLpLTTNSQLSPKSLLSQS------PSSLSS 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  887 TDTYHQQPQFPPVQQLQDSSTLESQALS-TSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLqaqgsqflEDNEDQSRR 965
Cdd:COG5048    251 SDSSSSASESPRSSLPTASSQSSSPNESdSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN--------HSGESLKPF 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  966 SYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKS-------HEKTHTGVKAFSCSV--CNASFTTNG 1036
Cdd:COG5048    323 SCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDS 402

                          410
                   ....*....|....*....
gi 2462561429 1037 SLTRHMATHMSMKPYKCPF 1055
Cdd:COG5048    403 NLSLHIITHLSFRPYNCKN 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
552-577 2.76e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.66  E-value: 2.76e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561429  552 SLKVHIRLHTGVRPFACPHCDKKFRT 577
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 197-219 3.19e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 39.59  E-value: 3.19e-04
                           10        20
                   ....*....|....*....|...
gi 2462561429  197 YSCPHCGKTFQKPSQLTRHIRIH 219
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
auto_AIDA-I NF033176
autotransporter adhesin AIDA-I;
1393-1595 4.58e-04

autotransporter adhesin AIDA-I;


Pssm-ID: 380183 [Multi-domain]  Cd Length: 1287  Bit Score: 45.42  E-value: 4.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1393 SILQQTLQQGNLLAQQLTGEPG--LAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSG 1470
Cdd:NF033176     6 SIVWNHSRQAWVVASELARGHGfvLAKNTLLVLAVASTIGNAFAQNISSGVVSGGVVSSGETQVVYSNGQTSNATVNSGG 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1471 TQDLTqvmtsqglvspSGGPHEITlTINNSSLSQVLAQAAGPTATSSSGSPQEItltiselntTSGSLPSTTPMSPSAIS 1550
Cdd:NF033176    86 IQNVN-----------NGGKTTST-TVNSSGAQNVGNSGTAISTIVNSGGVQRV---------SSGGVTSATSLSGGAQN 144

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561429 1551 TQNLvmsssgvgGDASVTLTL-ADTQGMLSGGLDTVTlNITSQGQQ 1595
Cdd:NF033176   145 IYNL--------GHASNTVIFnGGNQTIFSGGISDDT-NISSGGQQ 181
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1659-1707 4.72e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.62  E-value: 4.72e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2462561429 1659 CLECDRAFSSAAVLMHHSKEVHGRerihgCPVCRKAFKRATHLKEHMQT 1707
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1037-1062 4.74e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 4.74e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561429 1037 SLTRHMATHMSMKPYKCPFCEEGFRT 1062
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1764-1789 5.49e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 5.49e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561429 1764 ALQVHMKKHTGERPYKCAYCVMGFTQ 1789
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 683-732 6.21e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.23  E-value: 6.21e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462561429  683 KPFkCSQCGRGFVSAGVLKAHIRTHTglksFKCLICNGAFTTGGSLRRHM 732
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1237-1262 7.44e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 7.44e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561429 1237 SLKVHMRLHTGAKPFKCPHCELRFRT 1262
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 969-1013 1.03e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.46  E-value: 1.03e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 2462561429  969 CDYCNKGFKKSSHLKQHVRSHTgekpYKCKLCGRGFVSSGVLKSH 1013
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 967-989 1.76e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 37.28  E-value: 1.76e-03
                           10        20
                   ....*....|....*....|...
gi 2462561429  967 YRCDYCNKGFKKSSHLKQHVRSH 989
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 199-244 2.20e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 2.20e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561429  199 CPHCGKTFQKPSQLTRHIRIHTgerpFKCSECGKAFNQKGALQTHM 244
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
506-763 2.93e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.38  E-value: 2.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  506 HEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCM--KSFSTSGSLKVHIRLHTG--------------------- 562
Cdd:COG5048     30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGcdKSFSRPLELSRHLRTHHNnpsdlnskslplsnskassss 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  563 --------VRPFACPHCDKKFRT------SGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNVPVPDIPLQEPILITD 628
Cdd:COG5048    110 lsssssnsNDNNLLSSHSLPPSSrdpqlpDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLIS 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  629 LGLIQPIPK------NQFFQSYFNNNFVNEADRPYKCFYCHRAYK-KSCHLKQHIRSHTGEKPFKCS--------QCGRG 693
Cdd:COG5048    190 SNVSTSIPSssenspLSSSYSIPSSSSDQNLENSSSSLPLTTNSQlSPKSLLSQSPSSLSSSDSSSSasesprssLPTAS 269

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462561429  694 FVSAGVLKAHIRTHTG-LKSFKCLICNGAFTTGGSLRRHM--GIHN--DLRPYMCPY--CQKTFKTSLNCKKHMKTH 763
Cdd:COG5048    270 SQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSgeSLKPFSCPYslCGKLFSRNDALKRHILLH 346
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 225-247 3.16e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.51  E-value: 3.16e-03
                           10        20
                   ....*....|....*....|...
gi 2462561429  225 FKCSECGKAFNQKGALQTHMIKH 247
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 508-556 4.00e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.92  E-value: 4.00e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2462561429  508 KPFkCPQCFRAFAVKSTLTAHIKTHTgikaFKCQYCMKSFSTSGSLKVH 556
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1193-1242 5.26e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.54  E-value: 5.26e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1193 KPYkCDECGKSFTVKSTLDCHVKTHTgqklFSCHVCSNAFSTKGSLKVHM 1242
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-H2C2_2 pfam13465
Zinc-finger double domain;
727-752 5.41e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 5.41e-03
                           10        20
                   ....*....|....*....|....*.
gi 2462561429  727 SLRRHMGIHNDLRPYMCPYCQKTFKT 752
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1705-1773 5.87e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.22  E-value: 5.87e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462561429 1705 MQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQK--SALQVHMKKHT 1773
Cdd:COG5048     17 SSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHH 87
SP3_N cd22537
N-terminal domain of transcription factor Specificity Protein (SP) 3; Specificity Proteins ...
 1288-1573 7.65e-03

N-terminal domain of transcription factor Specificity Protein (SP) 3; Specificity Proteins (SPs) are transcription factors that are involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. SP1 and SP3 can interact with and recruit a large number of proteins including the transcription initiation complex, histone modifying enzymes, and chromatin remodeling complexes, which strongly suggest that SP1 and SP3 are important transcription factors in remodeling chromatin and the regulation of gene expression. SP3 belongs to a family of proteins, called the SP/Kruppel or Krueppel-like Factor (KLF) family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. SP factors preferentially bind GC boxes, while KLFs bind CACCC boxes. Another characteristic hallmark of SP factors is the presence of the Buttonhead (BTD) box CXCPXC, just N-terminal to the zinc fingers. The function of the BTD box is unknown, but it is thought to play an important physiological role. Another feature of most SP factors is the presence of a conserved amino acid stretch, the so-called SP box, located close to the N-terminus. SP factors may be separated into three groups based on their domain architecture and the similarity of their N-terminal transactivation domains: SP1-4, SP5, and SP6-9. The transactivation domains between the three groups are not homologous to one another. SP1-4 have similar N-terminal transactivation domains characterized by glutamine-rich regions, which, in most cases, have adjacent serine/threonine-rich regions. This model represents the N-terminal domain of SP3.


Pssm-ID: 411774 [Multi-domain]  Cd Length: 574  Bit Score: 41.09  E-value: 7.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1288 SSSEGLQPVNLLNSSSTDPNVFIMNNSvlTGQFDQNLLQPGLVGQAILPASVSAGG----DLTVSLTDGSLATLEGIQLQ 1363
Cdd:cd22537    259 NSGESGKVSPDINETNTNADLFVPTSS--SSQLPVTIDSTGILQQNASSLTTVSGQvhtsDLQGNYIQAPVSDETQAQNI 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1364 LAANLVGPNVQISGIDAASinnitlQIDPSILQQTLQQGNLLAQQLTGE---PGLAPQNSSLQTSDstvPASVVIQpisg 1440
Cdd:cd22537    337 QVSTAQPSVQQIQLHESQQ------PTSQAQIVQGITQQAIQGVQALGAqaiPQQALQNLQLQLLN---PGTFLIQ---- 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429 1441 lslQPTVTSanltigplSEQDSVLTTNSSGTQDLtqvmtsQGLVSPSGGPHEITLT-INNSSLSQVLAQAAG---PTATS 1516
Cdd:cd22537    404 ---AQTVTP--------SGQITWQTFQVQGVQNL------QNLQIQNAPAQQITLTpVQTLTLGQVGAGGAItstPVSLS 466

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462561429 1517 SSGSPQEITLTISELNTTSGSL-PSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLAD 1573
Cdd:cd22537    467 TGQLPNLQTVTVNSIDSAGIQLqQSENADSPADIQIKEEEPDSEEWQLSGDSTLNTND 524
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 991-1071 8.01e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.86  E-value: 8.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561429  991 GEKPYKCKL--CGRGFVSSGVLKSHEKT-HtgvkafscsvCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCK 1067
Cdd:COG5189    346 DGKPYKCPVegCNKKYKNQNGLKYHMLHgH----------QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                   ....
gi 2462561429 1068 KHMK 1071
Cdd:COG5189    416 YHRK 419
PHA00733 PHA00733
hypothetical protein
 535-585 8.17e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.32  E-value: 8.17e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462561429  535 IKAFKCQYCMKSFSTSGSLKVHIRL--HTGVrpfaCPHCDKKFRTSGHRKTHI 585
Cdd:PHA00733    71 VSPYVCPLCLMPFSSSVSLKQHIRYteHSKV----CPVCGKEFRNTDSTLDHV 119
PHA00733 PHA00733
hypothetical protein
 94-140 8.82e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.32  E-value: 8.82e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2462561429   94 TCPVCNKKFSRVASLKAHImlHEKEENLICSECGDEFTLQSQLAVHM 140
Cdd:PHA00733    75 VCPLCLMPFSSSVSLKQHI--RYTEHSKVCPVCGKEFRNTDSTLDHV 119
zf-H2C2_2 pfam13465
Zinc-finger double domain;
525-549 9.75e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 9.75e-03
                           10        20
                   ....*....|....*....|....*
gi 2462561429  525 LTAHIKTHTGIKAFKCQYCMKSFST 549
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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