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Conserved domains on  [gi|2462561433|ref|XP_054175071|]
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zinc finger protein 236 isoform X2 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 15210886)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation; similar to Saccharomyces cerevisiae zinc-responsive transcriptional regulator ZAP1 that controls zinc-responsive gene expression

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940|10940247|12665246|11179890
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
140-650 2.45e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 61.64  E-value: 2.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  140 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 217
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  218 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPQNSTSSTETAHVLTATLFQ-TLPLQQTEAQATSA 290
Cdd:COG5048    104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHpPLPANSLSKDPSSN 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  291 SSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSitvgiNQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQ 370
Cdd:COG5048    184 LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLE-----NSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  371 NPDVSSVSNEQTdptdaeqekeqespekldkkekkmiKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHT 450
Cdd:COG5048    259 ESPRSSLPTASS-------------------------QSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  451 HE----KPFKCPQcfrafavkstltahikthtgikafkcQYCMKSFSTSGSLKVHIRLHTGVRPFACP--HCDKKFrtsg 524
Cdd:COG5048    314 HSgeslKPFSCPY--------------------------SLCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKF---- 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  525 hrkthiaSHFKHTELRKMRHQRKpakvrvgktnvpvpdIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKC 604
Cdd:COG5048    364 -------SPLLNNEPPQSLQQYK---------------DLKNDKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKN 421

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561433  605 FYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRgFVSAGVLKAHIR 650
Cdd:COG5048    422 PPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1282-1558 7.20e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.85  E-value: 7.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1282 ASVSAGGDLTVSL--TDGSLaTLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPG 1359
Cdd:COG3210    802 GTITAAGTTAINVtgSGGTI-TINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVG 880

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1360 LAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEIT 1439
Cdd:COG3210    881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1440 LTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADT 1519
Cdd:COG3210    961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATA 1040

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2462561433 1520 QGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGS 1558
Cdd:COG3210   1041 GGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGG 1079
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
896-1258 3.22e-06

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.62  E-value: 3.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  896 QGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH---EKTHTGVKAFSCSV 972
Cdd:COG5048     18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSrhlRTHHNNPSDLNSKS 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  973 CNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTV--------HCKKHMKRHQTV-------PSAVSATGETEGGDIC 1037
Cdd:COG5048     98 LPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDpqlpdllsISNLRNNPLPGNnsssvntPQSNSLHPPLPANSLS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1038 MEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV-QSAAEKDRISELRDKQAELQDEPKHANcCTY 1116
Cdd:COG5048    178 KDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSsLPLTTNSQLSPKSLLSQSPSSLSSSDS-SSS 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1117 CPKSFKKPSDLVRHVRIH----------TGEKPYKCDECGKSFTVKSTLDCHVKT--HTGQKL--FSCHV--CSNAFSTK 1180
Cdd:COG5048    257 ASESPRSSLPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRSvnHSGESLkpFSCPYslCGKLFSRN 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1181 GSLKVHMRLHTGAKPFKCP--HCELRFRTSGRRKTHMQFHYKPDPKKARKPMTrsSSEGLQPVNLLNSSSTDPNVFIMNN 1258
Cdd:COG5048    337 DALKRHILLHTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKNDKKSET--LSNSCIRNFKRDSNLSLHIITHLSF 414
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1682-1706 2.92e-05

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.36  E-value: 2.92e-05
                           10        20
                   ....*....|....*....|....*
gi 2462561433 1682 LERHSRIHTGERPFHCTLCEKAFNQ 1706
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1-177 3.73e-05

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.54  E-value: 3.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433    1 MRDHERNDKPHRCDQCPQTFNVEFNLTLHK--CTHSGEDPT---CPV--CNKKFSRVASLKAHIMLHEKEENLICSECGD 73
Cdd:COG5048    280 SSSEKGFSLPIKSKQCNISFSRSSPLTRHLrsVNHSGESLKpfsCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNS 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433   74 EFTlqsqlavHMEEHRQELAGTRQHACKACK-KEFETS-SELKEHMKTHYKIRVSSTRSYNRNIDRsgftYSCPHCGKTF 151
Cdd:COG5048    360 SSK-------FSPLLNNEPPQSLQQYKDLKNdKKSETLsNSCIRNFKRDSNLSLHIITHLSFRPYN----CKNPPCSKSF 428

                          170       180
                   ....*....|....*....|....*.
gi 2462561433  152 QKPSQLTRHIRIHTGERPFKCSECGK 177
Cdd:COG5048    429 NRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
596-1000 7.60e-05

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.38  E-value: 7.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  596 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHIRTHTGLKSFKCLICNG-AFTTGGS 672
Cdd:COG5048     28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  673 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTvdqqsmqASTQMQVEIESDELPQ 752
Cdd:COG5048    108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQS-------NSLHPPLPANSLSKDP 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  753 TAEVVAANPEAMLDLEPQHvvgtEEAGLGQQLADQPLEADEDGFVAPQDPL-RGHVDQFEEQSPAQQSfepaglPQGFTV 831
Cdd:COG5048    181 SSNLSLLISSNVSTSIPSS----SENSPLSSSYSIPSSSSDQNLENSSSSLpLTTNSQLSPKSLLSQS------PSSLSS 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  832 TDTYHQQPQFPPVQQLQDSSTLESQALS-TSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLqaqgsqflEDNEDQSRR 910
Cdd:COG5048    251 SDSSSSASESPRSSLPTASSQSSSPNESdSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN--------HSGESLKPF 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  911 SYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKS-------HEKTHTGVKAFSCSV--CNASFTTNG 981
Cdd:COG5048    323 SCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDS 402

                          410
                   ....*....|....*....
gi 2462561433  982 SLTRHMATHMSMKPYKCPF 1000
Cdd:COG5048    403 NLSLHIITHLSFRPYNCKN 421
SUF4-like super family cl41227
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1604-1652 4.27e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


The actual alignment was detected with superfamily member cd20908:

Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.62  E-value: 4.27e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2462561433 1604 CLECDRAFSSAAVLMHHSKEVHGRerihgCPVCRKAFKRATHLKEHMQT 1652
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1709-1734 5.02e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 5.02e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561433 1709 ALQVHMKKHTGERPYKCAYCVMGFTQ 1734
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
140-650 2.45e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 61.64  E-value: 2.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  140 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 217
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  218 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPQNSTSSTETAHVLTATLFQ-TLPLQQTEAQATSA 290
Cdd:COG5048    104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHpPLPANSLSKDPSSN 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  291 SSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSitvgiNQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQ 370
Cdd:COG5048    184 LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLE-----NSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  371 NPDVSSVSNEQTdptdaeqekeqespekldkkekkmiKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHT 450
Cdd:COG5048    259 ESPRSSLPTASS-------------------------QSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  451 HE----KPFKCPQcfrafavkstltahikthtgikafkcQYCMKSFSTSGSLKVHIRLHTGVRPFACP--HCDKKFrtsg 524
Cdd:COG5048    314 HSgeslKPFSCPY--------------------------SLCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKF---- 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  525 hrkthiaSHFKHTELRKMRHQRKpakvrvgktnvpvpdIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKC 604
Cdd:COG5048    364 -------SPLLNNEPPQSLQQYK---------------DLKNDKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKN 421

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561433  605 FYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRgFVSAGVLKAHIR 650
Cdd:COG5048    422 PPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1282-1558 7.20e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.85  E-value: 7.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1282 ASVSAGGDLTVSL--TDGSLaTLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPG 1359
Cdd:COG3210    802 GTITAAGTTAINVtgSGGTI-TINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVG 880

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1360 LAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEIT 1439
Cdd:COG3210    881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1440 LTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADT 1519
Cdd:COG3210    961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATA 1040

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2462561433 1520 QGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGS 1558
Cdd:COG3210   1041 GGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGG 1079
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
896-1258 3.22e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.62  E-value: 3.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  896 QGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH---EKTHTGVKAFSCSV 972
Cdd:COG5048     18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSrhlRTHHNNPSDLNSKS 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  973 CNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTV--------HCKKHMKRHQTV-------PSAVSATGETEGGDIC 1037
Cdd:COG5048     98 LPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDpqlpdllsISNLRNNPLPGNnsssvntPQSNSLHPPLPANSLS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1038 MEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV-QSAAEKDRISELRDKQAELQDEPKHANcCTY 1116
Cdd:COG5048    178 KDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSsLPLTTNSQLSPKSLLSQSPSSLSSSDS-SSS 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1117 CPKSFKKPSDLVRHVRIH----------TGEKPYKCDECGKSFTVKSTLDCHVKT--HTGQKL--FSCHV--CSNAFSTK 1180
Cdd:COG5048    257 ASESPRSSLPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRSvnHSGESLkpFSCPYslCGKLFSRN 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1181 GSLKVHMRLHTGAKPFKCP--HCELRFRTSGRRKTHMQFHYKPDPKKARKPMTrsSSEGLQPVNLLNSSSTDPNVFIMNN 1258
Cdd:COG5048    337 DALKRHILLHTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKNDKKSET--LSNSCIRNFKRDSNLSLHIITHLSF 414
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1126-1150 3.29e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.05  E-value: 3.29e-06
                           10        20
                   ....*....|....*....|....*
gi 2462561433 1126 DLVRHVRIHTGEKPYKCDECGKSFT 1150
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
157-181 8.17e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 8.17e-06
                           10        20
                   ....*....|....*....|....*
gi 2462561433  157 LTRHIRIHTGERPFKCSECGKAFNQ 181
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1682-1706 2.92e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.36  E-value: 2.92e-05
                           10        20
                   ....*....|....*....|....*
gi 2462561433 1682 LERHSRIHTGERPFHCTLCEKAFNQ 1706
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1-177 3.73e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.54  E-value: 3.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433    1 MRDHERNDKPHRCDQCPQTFNVEFNLTLHK--CTHSGEDPT---CPV--CNKKFSRVASLKAHIMLHEKEENLICSECGD 73
Cdd:COG5048    280 SSSEKGFSLPIKSKQCNISFSRSSPLTRHLrsVNHSGESLKpfsCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNS 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433   74 EFTlqsqlavHMEEHRQELAGTRQHACKACK-KEFETS-SELKEHMKTHYKIRVSSTRSYNRNIDRsgftYSCPHCGKTF 151
Cdd:COG5048    360 SSK-------FSPLLNNEPPQSLQQYKDLKNdKKSETLsNSCIRNFKRDSNLSLHIITHLSFRPYN----CKNPPCSKSF 428

                          170       180
                   ....*....|....*....|....*.
gi 2462561433  152 QKPSQLTRHIRIHTGERPFKCSECGK 177
Cdd:COG5048    429 NRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
596-1000 7.60e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.38  E-value: 7.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  596 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHIRTHTGLKSFKCLICNG-AFTTGGS 672
Cdd:COG5048     28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  673 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTvdqqsmqASTQMQVEIESDELPQ 752
Cdd:COG5048    108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQS-------NSLHPPLPANSLSKDP 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  753 TAEVVAANPEAMLDLEPQHvvgtEEAGLGQQLADQPLEADEDGFVAPQDPL-RGHVDQFEEQSPAQQSfepaglPQGFTV 831
Cdd:COG5048    181 SSNLSLLISSNVSTSIPSS----SENSPLSSSYSIPSSSSDQNLENSSSSLpLTTNSQLSPKSLLSQS------PSSLSS 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  832 TDTYHQQPQFPPVQQLQDSSTLESQALS-TSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLqaqgsqflEDNEDQSRR 910
Cdd:COG5048    251 SDSSSSASESPRSSLPTASSQSSSPNESdSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN--------HSGESLKPF 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  911 SYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKS-------HEKTHTGVKAFSCSV--CNASFTTNG 981
Cdd:COG5048    323 SCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDS 402

                          410
                   ....*....|....*....
gi 2462561433  982 SLTRHMATHMSMKPYKCPF 1000
Cdd:COG5048    403 NLSLHIITHLSFRPYNCKN 421
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1604-1652 4.27e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.62  E-value: 4.27e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2462561433 1604 CLECDRAFSSAAVLMHHSKEVHGRerihgCPVCRKAFKRATHLKEHMQT 1652
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
auto_AIDA-I NF033176
autotransporter adhesin AIDA-I;
1338-1540 4.43e-04

autotransporter adhesin AIDA-I;


Pssm-ID: 380183 [Multi-domain]  Cd Length: 1287  Bit Score: 45.42  E-value: 4.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1338 SILQQTLQQGNLLAQQLTGEPG--LAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSG 1415
Cdd:NF033176     6 SIVWNHSRQAWVVASELARGHGfvLAKNTLLVLAVASTIGNAFAQNISSGVVSGGVVSSGETQVVYSNGQTSNATVNSGG 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1416 TQDLTqvmtsqglvspSGGPHEITlTINNSSLSQVLAQAAGPTATSSSGSPQEItltiselntTSGSLPSTTPMSPSAIS 1495
Cdd:NF033176    86 IQNVN-----------NGGKTTST-TVNSSGAQNVGNSGTAISTIVNSGGVQRV---------SSGGVTSATSLSGGAQN 144

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561433 1496 TQNLvmsssgvgGDASVTLTL-ADTQGMLSGGLDTVTlNITSQGQQ 1540
Cdd:NF033176   145 IYNL--------GHASNTVIFnGGNQTIFSGGISDDT-NISSGGQQ 181
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1709-1734 5.02e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 5.02e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561433 1709 ALQVHMKKHTGERPYKCAYCVMGFTQ 1734
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 628-677 5.96e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.23  E-value: 5.96e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462561433  628 KPFkCSQCGRGFVSAGVLKAHIRTHTglksFKCLICNGAFTTGGSLRRHM 677
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 914-958 9.36e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.85  E-value: 9.36e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 2462561433  914 CDYCNKGFKKSSHLKQHVRSHTgekpYKCKLCGRGFVSSGVLKSH 958
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 144-189 2.03e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 2.03e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561433  144 CPHCGKTFQKPSQLTRHIRIHTgerpFKCSECGKAFNQKGALQTHM 189
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-H2C2_2 pfam13465
Zinc-finger double domain;
672-697 5.00e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 5.00e-03
                           10        20
                   ....*....|....*....|....*.
gi 2462561433  672 SLRRHMGIHNDLRPYMCPYCQKTFKT 697
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
 480-530 7.84e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.32  E-value: 7.84e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462561433  480 IKAFKCQYCMKSFSTSGSLKVHIRL--HTGVrpfaCPHCDKKFRTSGHRKTHI 530
Cdd:PHA00733    71 VSPYVCPLCLMPFSSSVSLKQHIRYteHSKV----CPVCGKEFRNTDSTLDHV 119
PHA00733 PHA00733
hypothetical protein
 39-85 8.54e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.32  E-value: 8.54e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2462561433   39 TCPVCNKKFSRVASLKAHImlHEKEENLICSECGDEFTLQSQLAVHM 85
Cdd:PHA00733    75 VCPLCLMPFSSSVSLKQHI--RYTEHSKVCPVCGKEFRNTDSTLDHV 119
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
140-650 2.45e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 61.64  E-value: 2.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  140 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 217
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  218 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPQNSTSSTETAHVLTATLFQ-TLPLQQTEAQATSA 290
Cdd:COG5048    104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHpPLPANSLSKDPSSN 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  291 SSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSitvgiNQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQ 370
Cdd:COG5048    184 LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLE-----NSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  371 NPDVSSVSNEQTdptdaeqekeqespekldkkekkmiKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHT 450
Cdd:COG5048    259 ESPRSSLPTASS-------------------------QSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  451 HE----KPFKCPQcfrafavkstltahikthtgikafkcQYCMKSFSTSGSLKVHIRLHTGVRPFACP--HCDKKFrtsg 524
Cdd:COG5048    314 HSgeslKPFSCPY--------------------------SLCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKF---- 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  525 hrkthiaSHFKHTELRKMRHQRKpakvrvgktnvpvpdIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRPYKC 604
Cdd:COG5048    364 -------SPLLNNEPPQSLQQYK---------------DLKNDKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKN 421

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561433  605 FYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRgFVSAGVLKAHIR 650
Cdd:COG5048    422 PPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1282-1558 7.20e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.85  E-value: 7.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1282 ASVSAGGDLTVSL--TDGSLaTLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPG 1359
Cdd:COG3210    802 GTITAAGTTAINVtgSGGTI-TINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVG 880

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1360 LAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEIT 1439
Cdd:COG3210    881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1440 LTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADT 1519
Cdd:COG3210    961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATA 1040

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2462561433 1520 QGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGS 1558
Cdd:COG3210   1041 GGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGG 1079
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1242-1594 2.17e-07

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 56.31  E-value: 2.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1242 NLLNSSSTDPNVFIMNNSVLTGQFDQNLLQ--PGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQLAANLVGPNVQ 1319
Cdd:COG3210    639 VGAALSGTGSGTTGTASANGSNTTGVNTAGgtGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGSITVTGQ 718

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1320 ISGIDAASINNITLQIDPSILQQTLQQGNLLAqqlTGEPGlapqNSSLQTSDSTVpasvviqpISGLSLQPTVTSANLTI 1399
Cdd:COG3210    719 IGALANANGDTVTFGNLGTGATLTLNAGVTIT---SGNAG----TLSIGLTANTT--------ASGTTLTLANANGNTSA 783

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1400 GplseqdsvlTTNSSGTQDLTQVMTSQGLVSpSGGPHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTT 1479
Cdd:COG3210    784 G---------ATLDNAGAEISIDITADGTIT-AAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTT 853

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1480 SGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVT--LTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAG 1557
Cdd:COG3210    854 SDGASGGGTAGANSGSLAATAASITVGSGGVATStgTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAA 933

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 2462561433 1558 SPQVILVSHTPQSASAaceeIAYQVAGVSGNLAPGNQ 1594
Cdd:COG3210    934 GGTGAGNGTTALSGTQ----GNAGLSAASASDGAGDT 966
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
896-1258 3.22e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.62  E-value: 3.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  896 QGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH---EKTHTGVKAFSCSV 972
Cdd:COG5048     18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSrhlRTHHNNPSDLNSKS 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  973 CNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTV--------HCKKHMKRHQTV-------PSAVSATGETEGGDIC 1037
Cdd:COG5048     98 LPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDpqlpdllsISNLRNNPLPGNnsssvntPQSNSLHPPLPANSLS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1038 MEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLV-QSAAEKDRISELRDKQAELQDEPKHANcCTY 1116
Cdd:COG5048    178 KDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSsLPLTTNSQLSPKSLLSQSPSSLSSSDS-SSS 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1117 CPKSFKKPSDLVRHVRIH----------TGEKPYKCDECGKSFTVKSTLDCHVKT--HTGQKL--FSCHV--CSNAFSTK 1180
Cdd:COG5048    257 ASESPRSSLPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRSvnHSGESLkpFSCPYslCGKLFSRN 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1181 GSLKVHMRLHTGAKPFKCP--HCELRFRTSGRRKTHMQFHYKPDPKKARKPMTrsSSEGLQPVNLLNSSSTDPNVFIMNN 1258
Cdd:COG5048    337 DALKRHILLHTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKNDKKSET--LSNSCIRNFKRDSNLSLHIITHLSF 414
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1126-1150 3.29e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.05  E-value: 3.29e-06
                           10        20
                   ....*....|....*....|....*
gi 2462561433 1126 DLVRHVRIHTGEKPYKCDECGKSFT 1150
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
157-181 8.17e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 8.17e-06
                           10        20
                   ....*....|....*....|....*
gi 2462561433  157 LTRHIRIHTGERPFKCSECGKAFNQ 181
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
616-641 2.07e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 2.07e-05
                           10        20
                   ....*....|....*....|....*.
gi 2462561433  616 HLKQHIRSHTGEKPFKCSQCGRGFVS 641
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
926-951 2.22e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 2.22e-05
                           10        20
                   ....*....|....*....|....*.
gi 2462561433  926 HLKQHVRSHTGEKPYKCKLCGRGFVS 951
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1682-1706 2.92e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.36  E-value: 2.92e-05
                           10        20
                   ....*....|....*....|....*
gi 2462561433 1682 LERHSRIHTGERPFHCTLCEKAFNQ 1706
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1-177 3.73e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.54  E-value: 3.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433    1 MRDHERNDKPHRCDQCPQTFNVEFNLTLHK--CTHSGEDPT---CPV--CNKKFSRVASLKAHIMLHEKEENLICSECGD 73
Cdd:COG5048    280 SSSEKGFSLPIKSKQCNISFSRSSPLTRHLrsVNHSGESLKpfsCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNS 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433   74 EFTlqsqlavHMEEHRQELAGTRQHACKACK-KEFETS-SELKEHMKTHYKIRVSSTRSYNRNIDRsgftYSCPHCGKTF 151
Cdd:COG5048    360 SSK-------FSPLLNNEPPQSLQQYKDLKNdKKSETLsNSCIRNFKRDSNLSLHIITHLSFRPYN----CKNPPCSKSF 428

                          170       180
                   ....*....|....*....|....*.
gi 2462561433  152 QKPSQLTRHIRIHTGERPFKCSECGK 177
Cdd:COG5048    429 NRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
596-1000 7.60e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.38  E-value: 7.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  596 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHIRTHTGLKSFKCLICNG-AFTTGGS 672
Cdd:COG5048     28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  673 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTvdqqsmqASTQMQVEIESDELPQ 752
Cdd:COG5048    108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQS-------NSLHPPLPANSLSKDP 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  753 TAEVVAANPEAMLDLEPQHvvgtEEAGLGQQLADQPLEADEDGFVAPQDPL-RGHVDQFEEQSPAQQSfepaglPQGFTV 831
Cdd:COG5048    181 SSNLSLLISSNVSTSIPSS----SENSPLSSSYSIPSSSSDQNLENSSSSLpLTTNSQLSPKSLLSQS------PSSLSS 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  832 TDTYHQQPQFPPVQQLQDSSTLESQALS-TSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLqaqgsqflEDNEDQSRR 910
Cdd:COG5048    251 SDSSSSASESPRSSLPTASSQSSSPNESdSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVN--------HSGESLKPF 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  911 SYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKS-------HEKTHTGVKAFSCSV--CNASFTTNG 981
Cdd:COG5048    323 SCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDS 402

                          410
                   ....*....|....*....
gi 2462561433  982 SLTRHMATHMSMKPYKCPF 1000
Cdd:COG5048    403 NLSLHIITHLSFRPYNCKN 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
497-522 2.45e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.66  E-value: 2.45e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561433  497 SLKVHIRLHTGVRPFACPHCDKKFRT 522
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 142-164 2.80e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 39.59  E-value: 2.80e-04
                           10        20
                   ....*....|....*....|...
gi 2462561433  142 YSCPHCGKTFQKPSQLTRHIRIH 164
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1604-1652 4.27e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.62  E-value: 4.27e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2462561433 1604 CLECDRAFSSAAVLMHHSKEVHGRerihgCPVCRKAFKRATHLKEHMQT 1652
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
zf-H2C2_2 pfam13465
Zinc-finger double domain;
982-1007 4.38e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 4.38e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561433  982 SLTRHMATHMSMKPYKCPFCEEGFRT 1007
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
auto_AIDA-I NF033176
autotransporter adhesin AIDA-I;
1338-1540 4.43e-04

autotransporter adhesin AIDA-I;


Pssm-ID: 380183 [Multi-domain]  Cd Length: 1287  Bit Score: 45.42  E-value: 4.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1338 SILQQTLQQGNLLAQQLTGEPG--LAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSG 1415
Cdd:NF033176     6 SIVWNHSRQAWVVASELARGHGfvLAKNTLLVLAVASTIGNAFAQNISSGVVSGGVVSSGETQVVYSNGQTSNATVNSGG 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1416 TQDLTqvmtsqglvspSGGPHEITlTINNSSLSQVLAQAAGPTATSSSGSPQEItltiselntTSGSLPSTTPMSPSAIS 1495
Cdd:NF033176    86 IQNVN-----------NGGKTTST-TVNSSGAQNVGNSGTAISTIVNSGGVQRV---------SSGGVTSATSLSGGAQN 144

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561433 1496 TQNLvmsssgvgGDASVTLTL-ADTQGMLSGGLDTVTlNITSQGQQ 1540
Cdd:NF033176   145 IYNL--------GHASNTVIFnGGNQTIFSGGISDDT-NISSGGQQ 181
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1709-1734 5.02e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 5.02e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561433 1709 ALQVHMKKHTGERPYKCAYCVMGFTQ 1734
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 628-677 5.96e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.23  E-value: 5.96e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462561433  628 KPFkCSQCGRGFVSAGVLKAHIRTHTglksFKCLICNGAFTTGGSLRRHM 677
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1182-1207 6.81e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 6.81e-04
                           10        20
                   ....*....|....*....|....*.
gi 2462561433 1182 SLKVHMRLHTGAKPFKCPHCELRFRT 1207
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 914-958 9.36e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.85  E-value: 9.36e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 2462561433  914 CDYCNKGFKKSSHLKQHVRSHTgekpYKCKLCGRGFVSSGVLKSH 958
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 912-934 1.56e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 37.28  E-value: 1.56e-03
                           10        20
                   ....*....|....*....|...
gi 2462561433  912 YRCDYCNKGFKKSSHLKQHVRSH 934
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 144-189 2.03e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 2.03e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2462561433  144 CPHCGKTFQKPSQLTRHIRIHTgerpFKCSECGKAFNQKGALQTHM 189
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 170-192 2.81e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.89  E-value: 2.81e-03
                           10        20
                   ....*....|....*....|...
gi 2462561433  170 FKCSECGKAFNQKGALQTHMIKH 192
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
451-708 3.15e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.99  E-value: 3.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  451 HEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCM--KSFSTSGSLKVHIRLHTG--------------------- 507
Cdd:COG5048     30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGcdKSFSRPLELSRHLRTHHNnpsdlnskslplsnskassss 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  508 --------VRPFACPHCDKKFRT------SGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNVPVPDIPLQEPILITD 573
Cdd:COG5048    110 lsssssnsNDNNLLSSHSLPPSSrdpqlpDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLIS 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  574 LGLIQPIPK------NQFFQSYFNNNFVNEADRPYKCFYCHRAYK-KSCHLKQHIRSHTGEKPFKCS--------QCGRG 638
Cdd:COG5048    190 SNVSTSIPSssenspLSSSYSIPSSSSDQNLENSSSSLPLTTNSQlSPKSLLSQSPSSLSSSDSSSSasesprssLPTAS 269

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462561433  639 FVSAGVLKAHIRTHTG-LKSFKCLICNGAFTTGGSLRRHM--GIHN--DLRPYMCPY--CQKTFKTSLNCKKHMKTH 708
Cdd:COG5048    270 SQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSgeSLKPFSCPYslCGKLFSRNDALKRHILLH 346
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 453-501 3.76e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.92  E-value: 3.76e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2462561433  453 KPFkCPQCFRAFAVKSTLTAHIKTHTgikaFKCQYCMKSFSTSGSLKVH 501
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
672-697 5.00e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 5.00e-03
                           10        20
                   ....*....|....*....|....*.
gi 2462561433  672 SLRRHMGIHNDLRPYMCPYCQKTFKT 697
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1138-1187 5.05e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.54  E-value: 5.05e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462561433 1138 KPYkCDECGKSFTVKSTLDCHVKTHTgqklFSCHVCSNAFSTKGSLKVHM 1187
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1650-1718 6.03e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.22  E-value: 6.03e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462561433 1650 MQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQK--SALQVHMKKHT 1718
Cdd:COG5048     17 SSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHH 87
PHA00733 PHA00733
hypothetical protein
 480-530 7.84e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.32  E-value: 7.84e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462561433  480 IKAFKCQYCMKSFSTSGSLKVHIRL--HTGVrpfaCPHCDKKFRTSGHRKTHI 530
Cdd:PHA00733    71 VSPYVCPLCLMPFSSSVSLKQHIRYteHSKV----CPVCGKEFRNTDSTLDHV 119
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 936-1016 8.09e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.86  E-value: 8.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462561433  936 GEKPYKCKL--CGRGFVSSGVLKSHEKT-HtgvkafscsvCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCK 1012
Cdd:COG5189    346 DGKPYKCPVegCNKKYKNQNGLKYHMLHgH----------QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                   ....
gi 2462561433 1013 KHMK 1016
Cdd:COG5189    416 YHRK 419
PHA00733 PHA00733
hypothetical protein
 39-85 8.54e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.32  E-value: 8.54e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2462561433   39 TCPVCNKKFSRVASLKAHImlHEKEENLICSECGDEFTLQSQLAVHM 85
Cdd:PHA00733    75 VCPLCLMPFSSSVSLKQHI--RYTEHSKVCPVCGKEFRNTDSTLDHV 119
zf-H2C2_2 pfam13465
Zinc-finger double domain;
470-494 9.01e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 9.01e-03
                           10        20
                   ....*....|....*....|....*
gi 2462561433  470 LTAHIKTHTGIKAFKCQYCMKSFST 494
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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