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Conserved domains on  [gi|2462631777|ref|XP_054184169|]
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armadillo repeat-containing X-linked protein 2 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Arm_2 pfam04826
Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain ...
 383-601 6.58e-116

Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.


:

Pssm-ID: 461447 [Multi-domain]  Cd Length: 221  Bit Score: 344.78  E-value: 6.58e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQ 462
Cdd:pfam04826   1 LEPQELDKLLALLKSSEDPFIHEIALITLGNSAAYPFNQDIIRDLGGIPIIANLLSDSNPEVKEKALNALNNLSMNVENQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 463 GRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDML 542
Cdd:pfam04826  81 KKIKVYVNQVCKDIVSSPLNSEVQLAGLKLLTNLSVTNDYHHLVVSYIRDFFSLLSQGNEKTKFQVLKVLLNLSENPAMT 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462631777 543 KKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLRAE--VFNYREFNKGSLFYLCT 601
Cdd:pfam04826 161 RELLSAQVPSSLLSLFNSKEAKENLLRALTIFENINFHLKKEakLFVKEHFTKGSLFSIFR 221
PRK07003 super family cl35530
DNA polymerase III subunit gamma/tau;
39-279 2.00e-08

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07003:

Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.55  E-value: 2.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  39 AKPKNRAVAGTGARARAGLRAGftidlgsgfspPTPVRAEAEDRAQDEASAldtVGAEAVAPAASSAEAQSGAgsqaqEA 118
Cdd:PRK07003  379 AVPAPGARAAAAVGASAVPAVT-----------AVTGAAGAALAPKAAAAA---AATRAEAPPAAPAPPATAD-----RG 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 119 DGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPR-EAETSRAAVPPGTVVPTEAAAPTEVTEGP 197
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfEPAPRAAAPSAATPAAVPDARAPAAASRE 519

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 198 GVAAPTKVAeAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRtavvpGTSAAKKATPGAHTGAIPKATSATGA 277
Cdd:PRK07003  520 DAPAAAAPP-APEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDR-----GARAAAAAKPAAAPAAAPKPAAPRVA 593


                  ..
gi 2462631777 278 VP 279
Cdd:PRK07003  594 VQ 595
 
Name Accession Description Interval E-value
Arm_2 pfam04826
Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain ...
 383-601 6.58e-116

Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.


Pssm-ID: 461447 [Multi-domain]  Cd Length: 221  Bit Score: 344.78  E-value: 6.58e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQ 462
Cdd:pfam04826   1 LEPQELDKLLALLKSSEDPFIHEIALITLGNSAAYPFNQDIIRDLGGIPIIANLLSDSNPEVKEKALNALNNLSMNVENQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 463 GRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDML 542
Cdd:pfam04826  81 KKIKVYVNQVCKDIVSSPLNSEVQLAGLKLLTNLSVTNDYHHLVVSYIRDFFSLLSQGNEKTKFQVLKVLLNLSENPAMT 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462631777 543 KKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLRAE--VFNYREFNKGSLFYLCT 601
Cdd:pfam04826 161 RELLSAQVPSSLLSLFNSKEAKENLLRALTIFENINFHLKKEakLFVKEHFTKGSLFSIFR 221
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
39-279 2.00e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.55  E-value: 2.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  39 AKPKNRAVAGTGARARAGLRAGftidlgsgfspPTPVRAEAEDRAQDEASAldtVGAEAVAPAASSAEAQSGAgsqaqEA 118
Cdd:PRK07003  379 AVPAPGARAAAAVGASAVPAVT-----------AVTGAAGAALAPKAAAAA---AATRAEAPPAAPAPPATAD-----RG 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 119 DGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPR-EAETSRAAVPPGTVVPTEAAAPTEVTEGP 197
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfEPAPRAAAPSAATPAAVPDARAPAAASRE 519

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 198 GVAAPTKVAeAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRtavvpGTSAAKKATPGAHTGAIPKATSATGA 277
Cdd:PRK07003  520 DAPAAAAPP-APEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDR-----GARAAAAAKPAAAPAAAPKPAAPRVA 593


                  ..
gi 2462631777 278 VP 279
Cdd:PRK07003  594 VQ 595
VATPase_H cd00256
VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the ...
 388-455 1.68e-03

VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The topology is that of a superhelical spiral, in part the geometry is similar to superhelices composed of armadillo repeat motifs, as found in importins for example.


Pssm-ID: 238159 [Multi-domain]  Cd Length: 429  Bit Score: 41.23  E-value: 1.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462631777 388 LRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
Cdd:cd00256   355 LKILIHLLETSVDPIILAVACHDIGEYVRhYPRGKDVVEQLGGKQRVMRLLNHEDPNVRYEALLAVQKL 423
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 420-456 2.33e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.87  E-value: 2.33e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2462631777  420 NQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLS 456
Cdd:smart00185   4 NKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
KLF9_13_N-like cd21975
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ...
 164-290 8.54e-03

Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.


Pssm-ID: 409240 [Multi-domain]  Cd Length: 163  Bit Score: 37.36  E-value: 8.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 164 AEAPREAETSRAAVPPG----TVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESP 239
Cdd:cd21975    31 AAGLDVRATREVAKGPGppgpAWKPDGADSPGLVTAAPHLLAANVLAPLRGPSVEGSSLESGDADMGSDSDVAPASGAAA 110

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462631777 240 GTSgsprtavvPGTSAAKKATPGAHTGAIPKATSATGAVPKGGGKGVTRSR 290
Cdd:cd21975   111 STS--------PESSSDAASSPSPLSLLHPGEAGLEPERPRPRVRRGVRRR 153
 
Name Accession Description Interval E-value
Arm_2 pfam04826
Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain ...
 383-601 6.58e-116

Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.


Pssm-ID: 461447 [Multi-domain]  Cd Length: 221  Bit Score: 344.78  E-value: 6.58e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQ 462
Cdd:pfam04826   1 LEPQELDKLLALLKSSEDPFIHEIALITLGNSAAYPFNQDIIRDLGGIPIIANLLSDSNPEVKEKALNALNNLSMNVENQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 463 GRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDML 542
Cdd:pfam04826  81 KKIKVYVNQVCKDIVSSPLNSEVQLAGLKLLTNLSVTNDYHHLVVSYIRDFFSLLSQGNEKTKFQVLKVLLNLSENPAMT 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462631777 543 KKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLRAE--VFNYREFNKGSLFYLCT 601
Cdd:pfam04826 161 RELLSAQVPSSLLSLFNSKEAKENLLRALTIFENINFHLKKEakLFVKEHFTKGSLFSIFR 221
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
39-279 2.00e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.55  E-value: 2.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  39 AKPKNRAVAGTGARARAGLRAGftidlgsgfspPTPVRAEAEDRAQDEASAldtVGAEAVAPAASSAEAQSGAgsqaqEA 118
Cdd:PRK07003  379 AVPAPGARAAAAVGASAVPAVT-----------AVTGAAGAALAPKAAAAA---AATRAEAPPAAPAPPATAD-----RG 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 119 DGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPR-EAETSRAAVPPGTVVPTEAAAPTEVTEGP 197
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfEPAPRAAAPSAATPAAVPDARAPAAASRE 519

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 198 GVAAPTKVAeAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRtavvpGTSAAKKATPGAHTGAIPKATSATGA 277
Cdd:PRK07003  520 DAPAAAAPP-APEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDR-----GARAAAAAKPAAAPAAAPKPAAPRVA 593


                  ..
gi 2462631777 278 VP 279
Cdd:PRK07003  594 VQ 595
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
49-280 9.31e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 55.24  E-value: 9.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  49 TGARARAGLR----AGFTIDL---------------GSGFSPPTPVRA--EAEDRAQDEASALDTVGAEAVAPAASSAEA 107
Cdd:PRK07003  332 TVGRGELGLApdeyAGFTMTLlrmlafepavtgggaPGGGVPARVAGAvpAPGARAAAAVGASAVPAVTAVTGAAGAALA 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 108 QSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEA 187
Cdd:PRK07003  412 PKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFE 491

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 188 AAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATP--GAHT 265
Cdd:PRK07003  492 PAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSdrGARA 571

                         250
                  ....*....|....*
gi 2462631777 266 GAIPKATSATGAVPK 280
Cdd:PRK07003  572 AAAAKPAAAPAAAPK 586
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
59-272 2.44e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 53.73  E-value: 2.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  59 AGFTIDL-----------GSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKA 127
Cdd:PRK12323  351 AGFTMTLlrmlafrpgqsGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAP 430

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 128 ESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEV---TEGPG-VAAPT 203
Cdd:PRK12323  431 EALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPppwEELPPeFASPA 510

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462631777 204 KVAEAPGVAsPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKAT 272
Cdd:PRK12323  511 PAQPDAAPA-GWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFD 578
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
97-282 3.15e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 53.70  E-value: 3.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  97 AVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPG-VTEALGAAEAPAMAGAPKVAEAPREA----- 170
Cdd:PRK07003  357 AFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGaAGAALAPKAAAAAAATRAEAPPAAPAppata 436

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 171 -ETSRAAVPPGTVvPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAV 249
Cdd:PRK07003  437 dRGDDAADGDAPV-PAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAA 515

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2462631777 250 VPGTSAAKKATPGAHTGAIPKATSATGAVPKGG 282
Cdd:PRK07003  516 ASREDAPAAAAPPAPEARPPTPAAAAPAARAGG 548
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 35-271 1.69e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 51.14  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  35 KKRMAKPKNRAVAGTGARARAGLRAGFT--IDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAvAPAASSAEAQSGAG 112
Cdd:PRK07764  558 ARRFASPGNAEVLVTALAEELGGDWQVEavVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPA-APAAPAPAGAAAAP 636

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 113 SQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagapkvAEAPREAETSRAAVPPGTVVPTEAAAPTE 192
Cdd:PRK07764  637 AEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAK---------------AGGAAPAAPPPAPAPAAPAAPAGAAPAQP 701

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462631777 193 VTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKA 271
Cdd:PRK07764  702 APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
PHA03247 PHA03247
large tegument protein UL36; Provisional
 71-281 1.40e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 1.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777   71 PPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQ------EADGAGVGPKAESVVGAAMASAIAPPPG 144
Cdd:PHA03247  2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSArprapvDDRGDPRGPAPPSPLPPDTHAPDPPPPS 2630

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  145 VTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGpgvaaPTKVAEAPGVASPTEAAEAPvpa 224
Cdd:PHA03247  2631 PSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQR-----PRRRAARPTVGSLTSLADPP--- 2702

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462631777  225 tptgaaAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPKG 281
Cdd:PHA03247  2703 ------PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG 2753
PHA03247 PHA03247
large tegument protein UL36; Provisional
 11-280 1.94e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777   11 AAGIVIGAGAWYCVYKYTRGRDQTKKRMAKPKNRAVA-GTGARARAGLR------AGFTIDLGSGFSPPTPVRAEAEDRA 83
Cdd:PHA03247  2633 PAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRlGRAAQASSPPQrprrraARPTVGSLTSLADPPPPPPTPEPAP 2712

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777   84 QDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagaPKV 163
Cdd:PHA03247  2713 HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA------------GPP 2780

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  164 AEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPvpatptgaaaPTGAAESPGTSG 243
Cdd:PHA03247  2781 RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTA----------PPPPPGPPPPSL 2850

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 2462631777  244 SPRTAVVPGTSAAKKATPGAhtgaiPKATSATGAVPK 280
Cdd:PHA03247  2851 PLGGSVAPGGDVRRRPPSRS-----PAAKPAAPARPP 2882
PHA03247 PHA03247
large tegument protein UL36; Provisional
 71-282 3.11e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 3.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777   71 PPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVG-----PKAESVVGAAMASAIAPPPGV 145
Cdd:PHA03247  2627 PPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrprrRAARPTVGSLTSLADPPPPPP 2706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  146 TEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEV--------TEGPG--------VAAPTKVAEAP 209
Cdd:PHA03247  2707 TPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGParparpptTAGPPapappaapAAGPPRRLTRP 2786

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462631777  210 GVASPTEAAEA-PVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPKGG 282
Cdd:PHA03247  2787 AVASLSESRESlPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG 2860
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 83-223 1.04e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 45.48  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  83 AQDEASALDTV-----------GAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVtealga 151
Cdd:PRK14951  347 APDEYAALTMVllrllafkpaaAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAA------ 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 152 aeapamagapkVAEAPREAETSRAAVPPGTVVPTEAA---APTEVTEGPGVAAPTKVAEAPGVASPTEA-----AEAPVP 223
Cdd:PRK14951  421 -----------APPAPVAAPAAAAPAAAPAAAPAAVAlapAPPAQAAPETVAIPVRVAPEPAVASAAPApaaapAAARLT 489
rne PRK10811
ribonuclease E; Reviewed
 72-247 2.14e-04

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 44.65  E-value: 2.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777   72 PTPVRAEAEDRAQDEASALDTVGAEAVAPAA-----SSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPpgVT 146
Cdd:PRK10811   848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAvepvvSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAP--VT 925

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  147 EALGAAEApamagapkvAEAPREAETSRAAVPPGTVVP-TEAAAPTEVTEGPGVAAPTKVAEAPGVA---SPTEAAEAPV 222
Cdd:PRK10811   926 EQPQVITE---------SDVAVAQEVAEHAEPVVEPQDeTADIEEAAETAEVVVAEPEVVAQPAAPVvaeVAAEVETVTA 996

                          170       180
                   ....*....|....*....|....*
gi 2462631777  223 PATPTGAAAPTGAAESPGTSGSPRT 247
Cdd:PRK10811   997 VEPEVAPAQVPEATVEHNHATAPMT 1021
rne PRK10811
ribonuclease E; Reviewed
 71-221 2.35e-04

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 44.26  E-value: 2.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777   71 PPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPppgVTEAlg 150
Cdd:PRK10811   878 AVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEP---VVEP-- 952

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462631777  151 aaeapamagAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPgVAAPTKVAEAPGVASPTEA------AEAP 221
Cdd:PRK10811   953 ---------QDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAE-VETVTAVEPEVAPAQVPEAtvehnhATAP 1019
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 134-284 2.70e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 43.79  E-value: 2.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 134 AMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAET--SRAAVPPGTVvpteAAAPTEVTEGPG--VAAPTKVAEAP 209
Cdd:PTZ00436  203 AAAKKAAAPSGKKSAKAAAPAKAAAAPAKAAAPPAKAAAapAKAAAAPAKA----AAPPAKAAAPPAkaAAPPAKAAAPP 278

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462631777 210 GVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSA---AKKATPGAHTGAIPKATSATGAVPKGGGK 284
Cdd:PTZ00436  279 AKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAappAKAATPPAKAAAPPAKAAAAPVGKKAGGK 356
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
94-290 2.96e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.10  E-value: 2.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  94 GAEAVAPAASSAEAQSGAGSQAQEAdgAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETS 173
Cdd:PRK12323  370 GGAGPATAAAAPVAQPAPAAAAPAA--AAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 174 R--AAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVAS------PTEAAEAPVPATPTGAAAPTGAAESPGTSGSP 245
Cdd:PRK12323  448 PapAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPapadddPPPWEELPPEFASPAPAQPDAAPAGWVAESIP 527

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2462631777 246 RTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPKGGGKGVTRSR 290
Cdd:PRK12323  528 DPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASG 572
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 41-279 3.59e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 3.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  41 PKNRAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADG 120
Cdd:PRK07764  435 PAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRE 514

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 121 ------AGVG-------------PKAESVVG---------AAMASAIAPPPG---VTEALGAAEAPAMAGAPKVAEAPRE 169
Cdd:PRK07764  515 rwpeilAAVPkrsrktwaillpeATVLGVRGdtlvlgfstGGLARRFASPGNaevLVTALAEELGGDWQVEAVVGPAPGA 594

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 170 AETSRAAVPPGTVVPTEAAAPTEVT--EGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRT 247
Cdd:PRK07764  595 AGGEGPPAPASSGPPEEAARPAAPAapAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAG 674

                         250       260       270
                  ....*....|....*....|....*....|..
gi 2462631777 248 AVVPgTSAAKKATPGAHTGAIPKATSATGAVP 279
Cdd:PRK07764  675 GAAP-AAPPPAPAPAAPAAPAGAAPAQPAPAP 705
PHA03247 PHA03247
large tegument protein UL36; Provisional
 71-280 3.91e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 3.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777   71 PPTPVRAEAEDRAQDEASALDTV----GAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAiAPPPGVT 146
Cdd:PHA03247  2702 PPPPPTPEPAPHALVSATPLPPGpaaaRQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA-APAAGPP 2780

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  147 EALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEA--------- 217
Cdd:PHA03247  2781 RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlggsvapgg 2860

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  218 -------AEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPK 280
Cdd:PHA03247  2861 dvrrrppSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQ 2930
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 9-243 5.65e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 5.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777   9 CVAAGIVIGAGAWYCVYKYTRGRDQTKKRMAKPkNRAVAGTGARARAGLRAGftiDLGSGFSPPTPVRAEAEDRAQDEAS 88
Cdd:PRK07764  586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAP-AAPAAPAAPAPAGAAAAP---AEASAAPAPGVAAPEHHPKHVAVPD 661

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  89 ALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAEsvvgAAMASAIAPPPGVTEALGAAEAPAmagapkvAEAPR 168
Cdd:PRK07764  662 ASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQP----APAPAATPPAGQADDPAAQPPQAA-------QGASA 730

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462631777 169 EAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSG 243
Cdd:PRK07764  731 PSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVA 805
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
51-222 9.03e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 9.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  51 ARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQE-ADGAGVGPKAES 129
Cdd:PRK12323  405 APAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPvAAAAAAAPARAA 484

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 130 VVGAAMASAIAPPPgvTEALGAAEAPAMAGAPKVAEAPREAETS--------RAAVPPGTVVPTEAAAPTEVTEGPGVAA 201
Cdd:PRK12323  485 PAAAPAPADDDPPP--WEELPPEFASPAPAQPDAAPAGWVAESIpdpatadpDDAFETLAPAPAAAPAPRAAAATEPVVA 562

                         170       180
                  ....*....|....*....|.
gi 2462631777 202 PTKVAEAPGVASPTEAAEAPV 222
Cdd:PRK12323  563 PRPPRASASGLPDMFDGDWPA 583
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
44-242 1.04e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  44 RAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRA---EAEDRAQDEASALDTVGAEAVAPA-ASSAEAQSGAGSQAQEAD 119
Cdd:PRK12323  376 TAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAApaaAAAARAVAAAPARRSPAPEALAAArQASARGPGGAPAPAPAPA 455

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 120 GAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAetsrAAVPPGTVVPTEAAAPTEVTEGPGV 199
Cdd:PRK12323  456 AAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEF----ASPAPAQPDAAPAGWVAESIPDPAT 531

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2462631777 200 AAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTS 242
Cdd:PRK12323  532 ADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLP 574
VATPase_H cd00256
VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the ...
 388-455 1.68e-03

VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The topology is that of a superhelical spiral, in part the geometry is similar to superhelices composed of armadillo repeat motifs, as found in importins for example.


Pssm-ID: 238159 [Multi-domain]  Cd Length: 429  Bit Score: 41.23  E-value: 1.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462631777 388 LRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
Cdd:cd00256   355 LKILIHLLETSVDPIILAVACHDIGEYVRhYPRGKDVVEQLGGKQRVMRLLNHEDPNVRYEALLAVQKL 423
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 76-221 1.68e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 41.09  E-value: 1.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  76 RAEAEDRAQDEASALDTVGAEAVAPAAS-SAEAQSGAGSQAQEADGAGVGPKAESV-VGAAMASAIAPPPGVTEALGAAE 153
Cdd:PTZ00436  187 RARREDAAAAAAAKQKAAAKKAAAPSGKkSAKAAAPAKAAAAPAKAAAPPAKAAAApAKAAAAPAKAAAPPAKAAAPPAK 266

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462631777 154 APAMAGAPKVAEAPREAETSRAAVPPGTVvpteAAAPTEVTEGPG--VAAPTKVAEAPG--VASPTEAAEAP 221
Cdd:PTZ00436  267 AAAPPAKAAAPPAKAAAPPAKAAAPPAKA----AAAPAKAAAAPAkaAAAPAKAAAPPAkaAAPPAKAATPP 334
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 93-221 2.20e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 2.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  93 VGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPgvtealgaaeapaMAGAPKVAEAPREAET 172
Cdd:PRK07764  386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPA-------------PAPAPPSPAGNAPAGG 452

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2462631777 173 SRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAP 221
Cdd:PRK07764  453 APSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPA 501
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 420-456 2.33e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.87  E-value: 2.33e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2462631777  420 NQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLS 456
Cdd:smart00185   4 NKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
rne PRK10811
ribonuclease E; Reviewed
 100-279 2.60e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.18  E-value: 2.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  100 PAASSAEAQSGAGSQAQEADGAgvgPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagaPKVAEAP--REAETSRAAV 177
Cdd:PRK10811   846 PVVRPQDVQVEEQREAEEVQVQ---PVVAEVPVAAAVEPVVSAPVVEAV------------AEVVEEPvvVAEPQPEEVV 910

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  178 PPGTVVPTEAAAPteVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAK 257
Cdd:PRK10811   911 VVETTHPEVIAAP--VTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVA 988

                          170       180
                   ....*....|....*....|..
gi 2462631777  258 KATPGAHTGAIPKATSATGAVP 279
Cdd:PRK10811   989 AEVETVTAVEPEVAPAQVPEAT 1010
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 47-220 3.14e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 40.35  E-value: 3.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  47 AGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRA--------QDEASALDTvGAEAVAPAASSAEAQSGAGSQAQEA 118
Cdd:PRK13108  275 APKGREAPGALRGSEYVVDEALEREPAELAAAAVASAasavgpvgPGEPNQPDD-VAEAVKAEVAEVTDEVAAESVVQVA 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 119 DGagVGPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagaPKVAEAPREAETSRAAvppgtvvPTEAAA-PTEVTEGP 197
Cdd:PRK13108  354 DR--DGESTPAVEETSEADIEREQPGDLAG------------QAPAAHQVDAEAASAA-------PEEPAAlASEAHDET 412

                         170       180
                  ....*....|....*....|...
gi 2462631777 198 GVAAPTKVAEAPGVASPTEAAEA 220
Cdd:PRK13108  413 EPEVPEKAAPIPDPAKPDELAVA 435
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 136-262 3.18e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.47  E-value: 3.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 136 ASAIAPPPGVTEALGAAEAPAmagAPKVAEAPREAETSRAAVPPGTVVPTeAAAPTEVTEGPGVAAPTKVAEAPGVASPT 215
Cdd:PRK14951  368 AAAEAAAPAEKKTPARPEAAA---PAAAPVAQAAAAPAPAAAPAAAASAP-AAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2462631777 216 EAAEAPVPATPTGA-AAPTGAAESPGTSGSPRTAVVPGTSAAKKATPG 262
Cdd:PRK14951  444 AVALAPAPPAQAAPeTVAIPVRVAPEPAVASAAPAPAAAPAAARLTPT 491
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 168-279 3.18e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 3.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 168 REAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRT 247
Cdd:PRK07764  383 RRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAP 462

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2462631777 248 AVVPGTSAAKKATPGAHTGAIPKATSATGAVP 279
Cdd:PRK07764  463 SAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAP 494
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 40-189 5.51e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 39.70  E-value: 5.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  40 KPKNRAVAGTGARARAGLRAgftidlgsgfSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAeAQSGAGSQAQEAD 119
Cdd:PRK14951  365 KPAAAAEAAAPAEKKTPARP----------EAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAA-APPAPVAAPAAAA 433

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462631777 120 GAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTV----VPTEAAA 189
Cdd:PRK14951  434 PAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDVwhatVQQLAAA 507
PRK12727 PRK12727
flagellar biosynthesis protein FlhF;
71-224 7.01e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 237182 [Multi-domain]  Cd Length: 559  Bit Score: 39.59  E-value: 7.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  71 PPTPVRAEAEDRAQDEASALDTVgaeavapaASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASA----IAPPPGVT 146
Cdd:PRK12727   79 PAAPVHAPLKLSANANMSQRQRV--------ASAAEDMIAAMALRQPVSVPRQAPAAAPVRAASIPSPaaqaLAHAAAVR 150

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462631777 147 EALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTeAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPA 224
Cdd:PRK12727  151 TAPRQEHALSAVPEQLFADFLTTAPVPRAPVQAPVVAAP-APVPAIAAALAAHAAYAQDDDEQLDDDGFDLDDALPQI 227
KLF9_13_N-like cd21975
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ...
 164-290 8.54e-03

Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.


Pssm-ID: 409240 [Multi-domain]  Cd Length: 163  Bit Score: 37.36  E-value: 8.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 164 AEAPREAETSRAAVPPG----TVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESP 239
Cdd:cd21975    31 AAGLDVRATREVAKGPGppgpAWKPDGADSPGLVTAAPHLLAANVLAPLRGPSVEGSSLESGDADMGSDSDVAPASGAAA 110

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462631777 240 GTSgsprtavvPGTSAAKKATPGAHTGAIPKATSATGAVPKGGGKGVTRSR 290
Cdd:cd21975   111 STS--------PESSSDAASSPSPLSLLHPGEAGLEPERPRPRVRRGVRRR 153
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
70-214 9.34e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 39.06  E-value: 9.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  70 SPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASS----AEAQSGAGSQAQEADGAGVGPKAESVvGAAMASAIAPPPGV 145
Cdd:PRK07003  483 DAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASredaPAAAAPPAPEARPPTPAAAAPAARAG-GAAAALDVLRNAGM 561

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462631777 146 TeaLGAAEAPAMAGAPKVAEAPREAETSrAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASP 214
Cdd:PRK07003  562 R--VSSDRGARAAAAAKPAAAPAAAPKP-AAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPP 627
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 82-263 9.66e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 38.81  E-value: 9.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777  82 RAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPkAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAP 161
Cdd:PRK13108  277 KGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGP-GEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADR 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462631777 162 KVAEAPREAETSRAAVppgtvvptEAAAPTEvTEGPGVAAPtKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGT 241
Cdd:PRK13108  356 DGESTPAVEETSEADI--------EREQPGD-LAGQAPAAH-QVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPD 425

                         170       180
                  ....*....|....*....|..
gi 2462631777 242 SGSPRTAVVPGTSAAKKATPGA 263
Cdd:PRK13108  426 PAKPDELAVAGPGDDPAEPDGI 447
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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