|
Name |
Accession |
Description |
Interval |
E-value |
| BRCT_MDC1_rpt2 |
cd18441 |
second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; ... |
1995-2075 |
1.86e-43 |
|
second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the second BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is not conserved in this family.
Pssm-ID: 349394 Cd Length: 81 Bit Score: 152.92 E-value: 1.86e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1995 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEA 2074
Cdd:cd18441 1 LLEGYEIHVTPGVKPEPPQMKDIITCAGGTFLPSMPKTYKPQTVVISCPEDFPHCSPALKAGLPVVSAEFLLTGILRQEA 80
|
.
gi 2462492653 2075 K 2075
Cdd:cd18441 81 D 81
|
|
| FHA_MDC1 |
cd22665 |
forkhead associated (FHA) domain found in mediator of DNA damage checkpoint protein 1 (MDC1) ... |
32-131 |
1.12e-37 |
|
forkhead associated (FHA) domain found in mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also called nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438717 [Multi-domain] Cd Length: 97 Bit Score: 136.98 E-value: 1.12e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 32 GRLHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAwdKAPILRDCGSLNGTQIlRPPKVLSPGV 111
Cdd:cd22665 1 GRLKVFSQAHGPEKDFPLYEGENVIGRDPSCSVVLPDKSVSKQHACIEVDG--GTHLIEDLGSTNGTRI-GNKVRLKPNV 77
|
90 100
....*....|....*....|
gi 2462492653 112 SHRLRDQELILFADLLCQYH 131
Cdd:cd22665 78 RYELIDGDLLLFGDVKCQYV 97
|
|
| BRCT_MDC1_rpt1 |
cd17744 |
first BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; ... |
1893-1963 |
2.10e-27 |
|
first BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the first BRCT domain.
Pssm-ID: 349375 [Multi-domain] Cd Length: 72 Bit Score: 106.93 E-value: 2.10e-27
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462492653 1893 PKVLFTGVVD-ARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1963
Cdd:cd17744 1 PRVLFTGVSDkEEGEKIIKKLGGSVVDSVEDCTHLVTDKVRRTVKFLCALARGIPIVSPDWLEASIKANKFL 72
|
|
| BRCT_PAXIP1_rpt6_like |
cd18432 |
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1), second BRCT domain of mediator of DNA ... |
1995-2073 |
1.52e-26 |
|
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1), second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the sixth BRCT domain of PAXIP1 and the second BRCT domain of MDC1.
Pssm-ID: 349385 [Multi-domain] Cd Length: 85 Bit Score: 104.97 E-value: 1.52e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1995 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMP----RSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVL 2070
Cdd:cd18432 1 LFEGYTFYVTPNVKPPPEELKEIIEAAGGKVLKKLPtkriEDDDPDTIVISCEEDRKLWKPLKKKGIPIYSVEFILTGIL 80
|
...
gi 2462492653 2071 KQE 2073
Cdd:cd18432 81 RQK 83
|
|
| BRCT_PAXIP1_rpt5 |
cd17712 |
fifth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also ... |
1892-1963 |
1.49e-20 |
|
fifth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. This family corresponds to the fifth BRCT domain.
Pssm-ID: 349344 Cd Length: 75 Bit Score: 87.29 E-value: 1.49e-20
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462492653 1892 APKVLFTGVVDARGER---AVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1963
Cdd:cd17712 1 TPRVLFTGFDPVQVRKltkKVTILGGEVVESPQECTHLVAPKVSRTVKFLTAISVCKHIVTPEWLEESFKQGKFL 75
|
|
| BRCT_PAXIP1_rpt6 |
cd18440 |
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also ... |
1995-2073 |
8.04e-20 |
|
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. This family corresponds to the sixth BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is not conserved in this family.
Pssm-ID: 349393 Cd Length: 90 Bit Score: 85.73 E-value: 8.04e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1995 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSmPRSYKPQR----------VVITCPQDFPHCSIPLRVGLPLLSPEF 2064
Cdd:cd18440 1 LFKGKYFYITPGVKPSPSVLKEIIESAGGKVEKK-RPSLKKIMeknnqgppsyIIITCENDLHLCRDLFRKNIDVYNAEF 79
|
....*....
gi 2462492653 2065 LLTGVLKQE 2073
Cdd:cd18440 80 ILTGVLRQK 88
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1227-1757 |
1.68e-17 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 90.00 E-value: 1.68e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1227 ATRGRKNRSSVKTPEPVVPTAP-ELQPSTSTDQPVtSEPTYQAT----RGRKNRSSVKTPEPVVPTAPELRPSTsTDRPV 1301
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPsRLAPAILPDEPV-GEPVHPRMltwiRGLEELASDDAGDPPPPLPPAAPPAA-PDRSV 2568
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1302 -TPKPTSRttrsrtnmssvktpetvvPTAPELQiSTSTDQPVTPKPTsrttRSRTNMSSVKNPESTVPIAPeLPPSTSTE 1380
Cdd:PHA03247 2569 pPPRPAPR------------------PSEPAVT-SRARRPDAPPQSA----RPRAPVDDRGDPRGPAPPSP-LPPDTHAP 2624
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1381 QPVTPEPTSRATRGRKNRSSGKTP---ETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSvktPETVVPTAPELQP 1457
Cdd:PHA03247 2625 DPPPPSPSPAANEPDPHPPPTVPPperPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAA---RPTVGSLTSLADP 2701
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1458 StstDQPVTPEPTSQATrgrtdrsSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPEL 1537
Cdd:PHA03247 2702 P---PPPPTPEPAPHAL-------VSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAP 2771
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1538 QPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAP 1617
Cdd:PHA03247 2772 PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP 2851
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1618 -----EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAM 1692
Cdd:PHA03247 2852 lggsvAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462492653 1693 PVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQR 1757
Cdd:PHA03247 2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPL 2996
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
962-1640 |
7.48e-17 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 87.69 E-value: 7.48e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 962 ASSPTPEPGVGAG---DLPGPTSAPVPSGSQSGGRGSPVSPRrhqkgllnckmppaeKASRIRAAEKVSRGDQESPDACL 1038
Cdd:PHA03247 2491 AAGAAPDPGGGGPpdpDAPPAPSRLAPAILPDEPVGEPVHPR---------------MLTWIRGLEELASDDAGDPPPPL 2555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1039 PPTVPeAPAPPQKPLNSQSQKHLAPPPLlspllpsikpTVRKTRqdgsqeaPEAPlsseLEPFHPKPKIRTRKSSRMTPf 1118
Cdd:PHA03247 2556 PPAAP-PAAPDRSVPPPRPAPRPSEPAV----------TSRARR-------PDAP----PQSARPRAPVDDRGDPRGPA- 2612
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1119 PATSAAPEPHPststaqpvtPKPTSQATRSRTNRSSVKTPepvVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSvKT 1198
Cdd:PHA03247 2613 PPSPLPPDTHA---------PDPPPPSPSPAANEPDPHPP---PTVPPPERPRDDPAPGRVSRPRRARRLGRAAQAS-SP 2679
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1199 PETVVPTALE--LQPSTSTDRPVTSEPTSQAtrgRKNRSSVKTPEPVVPTAPELQPSTSTDQPVT-SEPTYQATRGRKNR 1275
Cdd:PHA03247 2680 PQRPRRRAARptVGSLTSLADPPPPPPTPEP---APHALVSATPLPPGPAAARQASPALPAAPAPpAVPAGPATPGGPAR 2756
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1276 ssvkTPEPVVPTAPElRPSTSTDRPVTPKPtsRTTRSRTNMSSVKTPETVVPTAPelqistSTDQPVTPKPTSRTTRSRT 1355
Cdd:PHA03247 2757 ----PARPPTTAGPP-APAPPAAPAAGPPR--RLTRPAVASLSESRESLPSPWDP------ADPPAAVLAPAAALPPAAS 2823
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1356 NMSSVKNPESTVPIAPELPPSTSteQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSqatrg 1435
Cdd:PHA03247 2824 PAGPLPPPTSAQPTAPPPPPGPP--PPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTE----- 2896
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1436 rtnrssvktPETVVPTAPELQPSTSTDQPVTPEPTSQAtrgrtdrSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTT 1515
Cdd:PHA03247 2897 ---------SFALPPDQPERPPQPQAPPPPQPQPQPPP-------PPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVP 2960
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1516 RGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSvktpESIVPIAPELQPSTSRNQLVTPEPT-- 1593
Cdd:PHA03247 2961 QPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWAS----SLALHEETDPPPVSLKQTLWPPDDTed 3036
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 2462492653 1594 SRATRCRTNRSSVKTPEPVVPTAPEPH-PTTSTDQPVTPKLTSRATRR 1640
Cdd:PHA03247 3037 SDADSLFDSDSERSDLEALDPLPPEPHdPFAHEPDPATPEAGARESPS 3084
|
|
| FHA |
cd00060 |
forkhead associated (FHA) domain superfamily; Forkhead-associated (FHA) domains are small ... |
33-110 |
1.04e-13 |
|
forkhead associated (FHA) domain superfamily; Forkhead-associated (FHA) domains are small phosphopeptide recognition modules mostly found in eubacteria and eukaryotes. It is about 95-120 residues long that fold into an 11-stranded beta-sandwich. FHA domains can mediate the recognition of phosphorylated and non-phosphorylated substrates, as well as protein oligomerization. They specifically recognize threonine phosphorylation (pThr) accompanying activation of protein serine/threonine kinases. FHA domains show diverse ligand specificity. They may recognize the pTXXD motif, the pTXXI/L motif, and TQ clusters (singly and multiply phosphorylated). In eukaryotes, FHA superfamily members include forkhead-type transcription factors, as well as other signaling proteins, such as many regulatory proteins, kinases, phosphatases, motor proteins called kinesins, and metabolic enzymes. Many of them localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. FHA domains play important roles in human diseases, particularly in relation to DNA damage responses and cancers. In bacteria, FHA domain-containing proteins may participate in injection of viral proteins into host cells, transmembrane transporters, and cell division. FHA domain-containing proteins rarely include more than one copy of the domain. The only exception in eukaryotes is the checkpoint kinase Rad53 from Saccharomyces cerevisiae, which harbors two FHA domains (FHA1 and FHA2) flanking a central kinase domain. The two FHA domains recognize different phosphorylated targets and function independently from one another. In contrast, Mycobacterium tuberculosis ABC transporter Rv1747 contains two FHA domains but only one of them is essential for protein function.
Pssm-ID: 438714 [Multi-domain] Cd Length: 92 Bit Score: 68.46 E-value: 1.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 33 RLHIFSGAHGPEKdFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQI----LRPPKVLS 108
Cdd:cd00060 1 RLIVLDGDGGGRE-FPLTKGVVTIGRSPDCDIVLDDPSVSRRHARIEVD--GGGVYLEDLGSTNGTFVngkrITPPVPLQ 77
|
..
gi 2462492653 109 PG 110
Cdd:cd00060 78 DG 79
|
|
| FHA |
COG1716 |
Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]; |
32-110 |
2.22e-13 |
|
Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms];
Pssm-ID: 441322 [Multi-domain] Cd Length: 96 Bit Score: 67.68 E-value: 2.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 32 GRLHIFSGAHGpEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEilAWDKAPILRDCGSLNGTQI----LRPPKVL 107
Cdd:COG1716 2 ARLVVLEGPLA-GRRFPLDGGPLTIGRAPDNDIVLDDPTVSRRHARIR--RDGGGWVLEDLGSTNGTFVngqrVTEPAPL 78
|
...
gi 2462492653 108 SPG 110
Cdd:COG1716 79 RDG 81
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1362-1830 |
3.83e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 75.75 E-value: 3.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1362 NPESTVPIAPELPPSTSTEQP--VTPEPTSRATRGR-----------KNRSSGKTPETLVPTAPKLEPSTSTDQP-VTPE 1427
Cdd:PHA03247 2497 DPGGGGPPDPDAPPAPSRLAPaiLPDEPVGEPVHPRmltwirgleelASDDAGDPPPPLPPAAPPAAPDRSVPPPrPAPR 2576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1428 PTSQATRGRTNRSSVKtPETVVPTAPeLQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1507
Cdd:PHA03247 2577 PSEPAVTSRARRPDAP-PQSARPRAP-VDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRD 2654
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1508 SEPTSRTTRGRKNRSSVKTPEtvvPAAPELQPSTSTDQPVTPEPTSRATrgrtnrssvktpesivPIAPELQPSTSRNQL 1587
Cdd:PHA03247 2655 DPAPGRVSRPRRARRLGRAAQ---ASSPPQRPRRRAARPTVGSLTSLAD----------------PPPPPPTPEPAPHAL 2715
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1588 VTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPV-TPKLTSRATRRKTNRSSVKTPKP--VEPAASDLEPFT 1664
Cdd:PHA03247 2716 VSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPaRPPTTAGPPAPAPPAAPAAGPPRrlTRPAVASLSESR 2795
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1665 PTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSA 1744
Cdd:PHA03247 2796 ESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKP 2875
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1745 PLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSrkrSLATMDSPPHQ 1824
Cdd:PHA03247 2876 AAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQP---PLAPTTDPAGA 2952
|
....*.
gi 2462492653 1825 KQPQRG 1830
Cdd:PHA03247 2953 GEPSGA 2958
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1120-1460 |
6.63e-13 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 74.18 E-value: 6.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1120 ATSAAPEPHPSTSTAQPVTPKPTsqatrSRTNRSSVKTPEPVVPTAPELQPS--TSTDQPVTSEPTSQVTR---GRKSRS 1194
Cdd:pfam05109 471 ADVTSPTPAGTTSGASPVTPSPS-----PRDNGTESKAPDMTSPTSAVTTPTpnATSPTPAVTTPTPNATSptlGKTSPT 545
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1195 SVKTPETvvPTALELQPSTSTDRPVTSEPTSQATrgrKNRSSVKTPEP--VVPTAPELQPSTST---------DQPVTSE 1263
Cdd:pfam05109 546 SAVTTPT--PNATSPTPAVTTPTPNATIPTLGKT---SPTSAVTTPTPnaTSPTVGETSPQANTtnhtlggtsSTPVVTS 620
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1264 P----TYQATRGRKNRSSVKTpepvvpTAPELRPStSTDRPVTPKPTSRTTRSRTNMSSVKTP--ETVVPTAPElqiSTS 1337
Cdd:pfam05109 621 PpknaTSAVTTGQHNITSSST------SSMSLRPS-SISETLSPSTSDNSTSHMPLLTSAHPTggENITQVTPA---STS 690
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1338 TDQPVT----PKPTSRTTRSRTNMSSVKNPESTVPIAPELPP--STSTEQPV---TPEPTSRATRGRKNRSSGKTPETLV 1408
Cdd:pfam05109 691 THHVSTsspaPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPknATSPQAPSgqkTAVPTVTSTGGKANSTTGGKHTTGH 770
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462492653 1409 PTAPKLEPST----STDQPVT--------PEPTSQATRGRTNRSS--VKTPETVVPTAPELQPSTS 1460
Cdd:pfam05109 771 GARTSTEPTTdyggDSTTPRTrynattylPPSTSSKLRPRWTFTSppVTTAQATVPVPPTSQPRFS 836
|
|
| BRCT_BRC1_like_rpt5 |
cd17743 |
fifth BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar ... |
1894-1960 |
1.96e-12 |
|
fifth BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins; Schizosaccharomyces pombe BRC1 is required for mitotic fidelity, specifically in the G2 phase of the cell cycle. It plays a role in chromatin organization. The family also includes Cryptococcus neoformans DNA ligase 4 (LIG4, also known as DNA ligase IV or polydeoxyribonucleotide synthase [ATP] 4), which is involved in dsDNA break repair, and plays a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologus end-joining. Members in this family contain six BRCT domains. This family corresponds to the fifth one.
Pssm-ID: 349374 Cd Length: 70 Bit Score: 64.19 E-value: 1.96e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462492653 1894 KVLFTGVVDARGE--RAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1960
Cdd:cd17743 2 RLLFTGYKLWTEKeiKKLKKLGISIVEDPDECTHLVAPKIVRTEKFLCALAYAPVIVTTDWLEACLKAG 70
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1322-1683 |
6.12e-12 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 71.10 E-value: 6.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1322 PETVVPTAPELQISTSTDQPVTPK-PTSRTTRSRTNMSSVKNPESTVPiapeLPPSTSTEQPVTPEPtsratrgrknrSS 1400
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKVIFSKaPESTTTSPTLNTTGFAAPNTTTG----LPSSTHVPTNLTAPA-----------ST 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1401 GKTPETLVPTAPKLEPSTSTDQPVTPEPTSqatrgRTNRSSVKTPETVVPTAPELQPSTSTDQP----VTPEPTSQA-TR 1475
Cdd:pfam05109 465 GPTVSTADVTSPTPAGTTSGASPVTPSPSP-----RDNGTESKAPDMTSPTSAVTTPTPNATSPtpavTTPTPNATSpTL 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1476 GRTDRSSVKTPETvvPTAPELQASASTDQPVTSEPTSRTTrGRKNRSSVKTPETVVPAAPELQPSTST---------DQP 1546
Cdd:pfam05109 540 GKTSPTSAVTTPT--PNATSPTPAVTTPTPNATIPTLGKT-SPTSAVTTPTPNATSPTVGETSPQANTtnhtlggtsSTP 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1547 VTPEP----TSRATRGRTNRSSVKTPE-SIVP--IAPELQPSTSRNQ------LVTPEPTSRATRCRTNRSSVKTpEPVV 1613
Cdd:pfam05109 617 VVTSPpknaTSAVTTGQHNITSSSTSSmSLRPssISETLSPSTSDNStshmplLTSAHPTGGENITQVTPASTST-HHVS 695
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462492653 1614 PTAPEPHPTTsTDQPVTPKLTSRATrrKTNRSSVKTPKPVEPAASdlePFTPTDQ-SVTPEAIAQGGQSKT 1683
Cdd:pfam05109 696 TSSPAPRPGT-TSQASGPGNSSTST--KPGEVNVTKGTPPKNATS---PQAPSGQkTAVPTVTSTGGKANS 760
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1280-1718 |
1.03e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 70.33 E-value: 1.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1280 TPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPElqiSTSTDQPVTPKPTSRTTRSRTNMSS 1359
Cdd:pfam05109 429 TTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTPAG---TTSGASPVTPSPSPRDNGTESKAPD 505
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1360 VKNPESTVPIApelPPSTSTEQPVTPEPTSRATrgrkNRSSGKTPETLVPTAPKlePSTSTDQPVTPEPTSQATRGRTNR 1439
Cdd:pfam05109 506 MTSPTSAVTTP---TPNATSPTPAVTTPTPNAT----SPTLGKTSPTSAVTTPT--PNATSPTPAVTTPTPNATIPTLGK 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1440 SSvktpetvvPTAPELQPSTSTDQPVTPEPTSQA-TRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGR 1518
Cdd:pfam05109 577 TS--------PTSAVTTPTPNATSPTVGETSPQAnTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRP 648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1519 KNRSSVKTPETVVPAAPELqPSTSTDQPVTPEPTSRATRGRTNRSSVKTPesivpiAPELQPSTsrnqlvtpepTSRATR 1598
Cdd:pfam05109 649 SSISETLSPSTSDNSTSHM-PLLTSAHPTGGENITQVTPASTSTHHVSTS------SPAPRPGT----------TSQASG 711
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1599 CRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKL---TSRATRRKTNRSSVKTPKPVEPAASDLEPFTPtdqsvtpeai 1675
Cdd:pfam05109 712 PGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTavpTVTSTGGKANSTTGGKHTTGHGARTSTEPTTD---------- 781
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 2462492653 1676 aQGGQSKTLRS--STVRAMPVPTTPEFQ-------SPVTTDQPISP-EPITQP 1718
Cdd:pfam05109 782 -YGGDSTTPRTryNATTYLPPSTSSKLRprwtftsPPVTTAQATVPvPPTSQP 833
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1350-1736 |
1.08e-11 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 69.60 E-value: 1.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1350 TTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTStdqPVTPEPT 1429
Cdd:pfam17823 53 KSSEQ*NFCAATAAPAPVTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSS---PSSAAQS 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1430 SQATRGRTNRSSVKTPETVVPTAP-ELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA--STDQPV 1506
Cdd:pfam17823 130 LPAAIAALPSEAFSAPRAAACRANaSAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSapATLTPA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1507 TSEPTSRTTRGRKNRSSVKTP-ETVVPAAPELQPSTSTDQPVTPepTSRATRGRTNRSSVKTPESIVPIAPELQPST--- 1582
Cdd:pfam17823 210 RGISTAATATGHPAAGTALAAvGNSSPAAGTVTAAVGTVTPAAL--ATLAAAAGTVASAAGTINMGDPHARRLSPAKhmp 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1583 SRNQLVTPEPTSRAtRCRTNRSSVKTPEPVVPTAPEPHPTtstdqpvtpkltsratrrktnrssvktpkpvePAASDLEP 1662
Cdd:pfam17823 288 SDTMARNPAAPMGA-QAQGPIIQVSTDQPVHNTAGEPTPS--------------------------------PSNTTLEP 334
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462492653 1663 FTPTDQSVTPEAIAQGGQSKTLRSStvrAMPVPTTPEFQSPVTTdqpiSPEPITQPSCIKRQRAAGNPGSLAAP 1736
Cdd:pfam17823 335 NTPKSVASTNLAVVTTTKAQAKEPS---ASPVPVLHTSMIPEVE----ATSPTTQPSPLLPTQGAAGPGILLAP 401
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1103-1510 |
1.61e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 69.95 E-value: 1.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1103 PKPKIRTRKSSRMTPFPAT---SAAPEPHPSTST------AQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPS-- 1171
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKvifSKAPESTTTSPTlnttgfAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTpa 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1172 --TSTDQPVTSEPTSqvtrgRKSRSSVKTPETVVPTALELQPS--TSTDRPVTSEPTSQATRGRKNRSS----VKTPepv 1243
Cdd:pfam05109 480 gtTSGASPVTPSPSP-----RDNGTESKAPDMTSPTSAVTTPTpnATSPTPAVTTPTPNATSPTLGKTSptsaVTTP--- 551
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1244 VPTAPELQPSTSTDQPVTSEPTYQATrgrKNRSSVKTPEP--VVPTAPELRPSTSTDRPVTPKPTSR---TTRSRTNMSS 1318
Cdd:pfam05109 552 TPNATSPTPAVTTPTPNATIPTLGKT---SPTSAVTTPTPnaTSPTVGETSPQANTTNHTLGGTSSTpvvTSPPKNATSA 628
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1319 VKTPETVVPTAPELQIS---TSTDQPVTPKpTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEP------TS 1389
Cdd:pfam05109 629 VTTGQHNITSSSTSSMSlrpSSISETLSPS-TSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPaprpgtTS 707
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1390 RATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPV---TPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTS-TDQPV 1465
Cdd:pfam05109 708 QASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSgqkTAVPTVTSTGGKANSTTGGKHTTGHGARTSTEPTTDyGGDST 787
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 2462492653 1466 TPEPTSQATRGRTDRSSVK-TPETVVPTAPELQASASTDQPVTSEP 1510
Cdd:pfam05109 788 TPRTRYNATTYLPPSTSSKlRPRWTFTSPPVTTAQATVPVPPTSQP 833
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1111-1549 |
3.75e-11 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 68.06 E-value: 3.75e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1111 KSSRMTPFPATSAAPEPHPSTstaqpvtpKPTSQATRSRTNRSSVKTPEpvvptapelqpSTSTDQPVTSEPTSQVTRGR 1190
Cdd:pfam17823 53 KSSEQ*NFCAATAAPAPVTLT--------KGTSAAHLNSTEVTAEHTPH-----------GTDLSEPATREGAADGAASR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1191 ----KSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGrknrSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1266
Cdd:pfam17823 114 alaaAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAA----PRAAIAAASAPHAASPAPRTAASSTTAASSTT 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1267 QATRGrKNRSSVKTPEPVVPTAPELRPSTSTdrpVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKP 1346
Cdd:pfam17823 190 AASSA-PTTAASSAPATLTPARGISTAATAT---GHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVAS 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1347 TSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPeTLVPTAPKLEPSTSTDQPVTP 1426
Cdd:pfam17823 266 AAGTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQAQGPIIQVSTDQPVHNTAGEP-TPSPSNTTLEPNTPKSVASTN 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1427 EPTSQATRGRTNRSSVkTPETVVPTA--PELQPSTSTDQPvTPEPTSQATRGRTdrssvktpetvVPTAPELQASASTDQ 1504
Cdd:pfam17823 345 LAVVTTTKAQAKEPSA-SPVPVLHTSmiPEVEATSPTTQP-SPLLPTQGAAGPG-----------ILLAPEQVATEATAG 411
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 2462492653 1505 PVTSEPTSRTTRGRKnrssvktpetvVPAAPELQPSTS------TDQPVTP 1549
Cdd:pfam17823 412 TASAGPTPRSSGDPK-----------TLAMASCQLSTQgqylvvTTDPLTP 451
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1473-1921 |
8.41e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 68.04 E-value: 8.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1473 ATRGRTDRSSVKTPETVVPTAPELQASAS-TDQPVTSEPTSRT---TRGRKNRSSVKTPETVVPAAPELQPSTsTDQPV- 1547
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPSRLAPAIlPDEPVGEPVHPRMltwIRGLEELASDDAGDPPPPLPPAAPPAA-PDRSVp 2569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1548 ----TPEPTSRATRGRTNRSSVKtPESIVPIAPELQPSTSRNQLvTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTT 1623
Cdd:PHA03247 2570 pprpAPRPSEPAVTSRARRPDAP-PQSARPRAPVDDRGDPRGPA-PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1624 STDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEP-FTPTDQSVTPEA--IAQGGQSKTLRSSTVRAMPVPTTPEF 1700
Cdd:PHA03247 2648 PPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRaARPTVGSLTSLAdpPPPPPTPEPAPHALVSATPLPPGPAA 2727
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1701 ---QSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLE-PKSQASRNQRWGAVRAAESLTAIPEPASP 1776
Cdd:PHA03247 2728 arqASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAgPPRRLTRPAVASLSESRESLPSPWDPADP 2807
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1777 QLLETPIHASQIQKVEPAGRSRFTPELQPKAS-----------------------QSRKRSLATMDSPPHQKQPQRGEVS 1833
Cdd:PHA03247 2808 PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPppppgppppslplggsvapggdvRRRPPSRSPAAKPAAPARPPVRRLA 2887
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1834 QKTViiKEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALG 1913
Cdd:PHA03247 2888 RPAV--SRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLG 2965
|
....*...
gi 2462492653 1914 GSLAGSAA 1921
Cdd:PHA03247 2966 ALVPGRVA 2973
|
|
| FHA |
pfam00498 |
FHA domain; The FHA (Forkhead-associated) domain is a phosphopeptide binding motif. |
55-110 |
1.36e-10 |
|
FHA domain; The FHA (Forkhead-associated) domain is a phosphopeptide binding motif.
Pssm-ID: 459831 [Multi-domain] Cd Length: 66 Bit Score: 58.74 E-value: 1.36e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462492653 55 VVGRMPDCSVALPFPSISKQHAEIEILAwDKAPILRDCGSLNGT-----QILRPPKVLSPG 110
Cdd:pfam00498 2 TIGRSPDCDIVLDDPSVSRRHAEIRYDG-GGRFYLEDLGSTNGTfvngqRLGPEPVRLKDG 61
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1324-1712 |
1.39e-10 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 66.14 E-value: 1.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1324 TVVPTAP-ELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTV-PIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSG 1401
Cdd:pfam17823 63 ATAAPAPvTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAAdGAASRALAAAASSSPSSAAQSLPAAIAALPSEAF 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1402 KTPETLVPTAP-KLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPST--STDQPVTPEPTSQATRGRT 1478
Cdd:pfam17823 143 SAPRAAACRANaSAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSapATLTPARGISTAATATGHP 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1479 DRSSVKTP-ETVVPTAPELQASASTDQPVTSepTSRTTRGRKNRSSVKTPETVVPAAPELQPSTST---DQPVTPEPTSR 1554
Cdd:pfam17823 223 AAGTALAAvGNSSPAAGTVTAAVGTVTPAAL--ATLAAAAGTVASAAGTINMGDPHARRLSPAKHMpsdTMARNPAAPMG 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1555 A-TRGRTNRSSVKTPesIVPIAPELQPSTSRNQLVTPEPTSRATRCRT--NRSSVKTPEPVVPTAPEPH----PTTSTDQ 1627
Cdd:pfam17823 301 AqAQGPIIQVSTDQP--VHNTAGEPTPSPSNTTLEPNTPKSVASTNLAvvTTTKAQAKEPSASPVPVLHtsmiPEVEATS 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1628 PVTPKLTSRATRRKTNRSSVKTPKPVEPAAsdlepfTPTDQSVTPEAIAQGGqSKTLRSSTVRampvPTTpEFQSPVTTD 1707
Cdd:pfam17823 379 PTTQPSPLLPTQGAAGPGILLAPEQVATEA------TAGTASAGPTPRSSGD-PKTLAMASCQ----LST-QGQYLVVTT 446
|
....*
gi 2462492653 1708 QPISP 1712
Cdd:pfam17823 447 DPLTP 451
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1119-1672 |
2.22e-09 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 63.18 E-value: 2.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1119 PATSAAPEPHPSTSTAQPVTPKPTSQAtrsrtnrssVKTPEPVVPTAPE---LQPSTSTDQPVTSEPTSQVTRGRKSRSS 1195
Cdd:PRK10263 339 PVTQTPPVASVDVPPAQPTVAWQPVPG---------PQTGEPVIAPAPEgypQQSQYAQPAVQYNEPLQQPVQPQQPYYA 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1196 VKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGrkNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNR 1275
Cdd:PRK10263 410 PAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAG--NAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQ 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1276 SSVKtPEPVVPTAPELRPSTSTDRPVtpkpTSRTTRSRTNMSS--------VKTPETVVPTAPELqiSTSTDQPVTPKPT 1347
Cdd:PRK10263 488 PVVE-PEPVVEETKPARPPLYYFEEV----EEKRAREREQLAAwyqpipepVKEPEPIKSSLKAP--SVAAVPPVEAAAA 560
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1348 SRTTRSRTNMSSVKNPESTVPIAPELPPSTSTeqpvTPEPTSRATRG----RKNRSSGKTPETLVPTAPKLePStstdQP 1423
Cdd:PRK10263 561 VSPLASGVKKATLATGAAATVAAPVFSLANSG----GPRPQVKEGIGpqlpRPKRIRVPTRRELASYGIKL-PS----QR 631
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1424 VTPEPTSQATRGRTNRSSVKTPETVVPTAPE---LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA 1500
Cdd:PRK10263 632 AAEEKAREAQRNQYDSGDQYNDDEIDAMQQDelaRQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRY 711
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1501 STDQPVTSEPTSRTTRgrkNRSSVKTPETVVPAAPELQPS-----TSTDQPVTPEPTSRATRGRTNRSSVKTPESivPIA 1575
Cdd:PRK10263 712 SGEQPAGANPFSLDDF---EFSPMKALLDDGPHEPLFTPIvepvqQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQ--PVA 786
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1576 PELQPSTSRnQLVTPEPTSRATRcRTNRSSVKTPEPVVPTAPEPhPTTSTDQPVTPKLTSRATRRKTNRSSVKTP--KPV 1653
Cdd:PRK10263 787 PQPQYQQPQ-QPVAPQPQYQQPQ-QPVAPQPQYQQPQQPVAPQP-QYQQPQQPVAPQPQDTLLHPLLMRNGDSRPlhKPT 863
|
570
....*....|....*....
gi 2462492653 1654 EPAASdLEPFTPTDQSVTP 1672
Cdd:PRK10263 864 TPLPS-LDLLTPPPSEVEP 881
|
|
| BRCT_BRC1_like_rpt6 |
cd18439 |
sixth (C-terminal) BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) ... |
1976-2073 |
2.89e-09 |
|
sixth (C-terminal) BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins; Schizosaccharomyces pombe BRC1 is required for mitotic fidelity, specifically in the G2 phase of the cell cycle. It plays a role in chromatin organization. The family also includes Cryptococcus neoformans DNA ligase 4 (LIG4, also known as DNA ligase IV or polydeoxyribonucleotide synthase [ATP] 4), which is involved in dsDNA break repair, and plays a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologus end-joining. Members in this family contains six BRCT domains. This family corresponds to the sixth repeat.
Pssm-ID: 349392 Cd Length: 116 Bit Score: 56.54 E-value: 2.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1976 EKNFGFSLQDALSRARERR--LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKP--------QRVVITCPQD 2045
Cdd:cd18439 1 EKKYGCTLAESLARAKANKgkLLKGYTVYLTPKVKGGVETFKSIVEANGGICNLLRAAKGKLgdgiaekgPVVLISTTKE 80
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2462492653 2046 ------------FPHCSIPLRvglpllSPEFLLTGVLKQE 2073
Cdd:cd18439 81 kklwpkflknarEGGKEPRVY------STDWLLDVVLRQE 114
|
|
| BRCT |
cd00027 |
C-terminal domain of the breast cancer suppressor protein (BRCA1) and related domains; The ... |
1893-1956 |
1.85e-08 |
|
C-terminal domain of the breast cancer suppressor protein (BRCA1) and related domains; The BRCT (BRCA1 C-terminus) domain is found within many DNA damage repair and cell cycle checkpoint proteins. BRCT domains interact with each other forming homo/hetero BRCT multimers, but are also involved in BRCT-non-BRCT interactions and interactions within DNA strand breaks. BRCT tandem repeats bind to phosphopeptides; it has been shown that the repeats in human BRCA1 bind specifically to pS-X-X-F motifs, mediating the interaction between BRCA1 and the DNA helicase BACH1, or BRCA1 and CtIP, a transcriptional corepressor. It is assumed that BRCT repeats play similar roles in many signaling pathways associated with the response to DNA damage.
Pssm-ID: 349339 [Multi-domain] Cd Length: 68 Bit Score: 52.75 E-value: 1.85e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462492653 1893 PKVLFTGVVDARGE---RAVLALGGSLAGS-AAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQS 1956
Cdd:cd00027 1 LVICFSGLDDEEREelkKLIEALGGKVSESlSSKVTHLIAKSPSGEKYYLAALAWGIPIVSPEWLLDC 68
|
|
| FHA |
smart00240 |
Forkhead associated domain; Found in eukaryotic and prokaryotic proteins. Putative nuclear ... |
55-100 |
3.22e-08 |
|
Forkhead associated domain; Found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain.
Pssm-ID: 214578 [Multi-domain] Cd Length: 52 Bit Score: 51.41 E-value: 3.22e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 2462492653 55 VVGRMP-DCSVALPFPSISKQHAEIEILAWDKApILRDCGSLNGTQI 100
Cdd:smart00240 2 TIGRSSeDCDIQLDGPSISRRHAVIVYDGGGRF-YLIDLGSTNGTFV 47
|
|
| BRCT_TopBP1_rpt7 |
cd17738 |
seventh BRCT domain of DNA topoisomerase 2-binding protein 1; TopBP1, also termed DNA ... |
1893-1960 |
1.17e-07 |
|
seventh BRCT domain of DNA topoisomerase 2-binding protein 1; TopBP1, also termed DNA topoisomerase II-beta-binding protein 1, or DNA topoisomerase II-binding protein 1, functions in DNA replication and damage response. It binds double-stranded DNA breaks and nicks as well as single-stranded DNA. TopBP1 contains six copies of BRCT domain. The family corresponds to the seventh BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is missing in this group.
Pssm-ID: 349370 [Multi-domain] Cd Length: 75 Bit Score: 50.64 E-value: 1.17e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462492653 1893 PKVLFTGVVDArgERA-----VLALGGSLAGSA---AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1960
Cdd:cd17738 2 PVFLLSGFSED--EKKelisiIEKLGGKVLDSDefdPKCTHLICGKPSRSEKFLAACAAGKWILHPSYIEASAKAG 75
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1271-1679 |
1.26e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 57.10 E-value: 1.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1271 GRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRT 1350
Cdd:PHA03307 38 GSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPP 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1351 TRSrtnMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRgrknrSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTS 1430
Cdd:PHA03307 118 PPT---PPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGA-----SPAAVASDAASSRQAALPLSSPEETARAPSSP 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1431 QATRGrTNRSSVKTPETVVPTAPELQPSTSTDQPVtPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1510
Cdd:PHA03307 190 PAEPP-PSTPPAAASPRPPRRSSPISASASSPAPA-PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPT 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1511 TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRatrgRTNRSSVKTPESIVPIAPELQPSTSRNQLVTP 1590
Cdd:PHA03307 268 RIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSS----PRASSSSSSSRESSSSSTSSSSESSRGAAVSP 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1591 EPTSRATRCRTNRSSVKTPEPVvPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPvEPAASDLEPFTPTDQSV 1670
Cdd:PHA03307 344 GPSPSRSPSPSRPPPPADPSSP-RKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDAT-GRFPAGRPRPSPLDAGA 421
|
....*....
gi 2462492653 1671 TPEAIAQGG 1679
Cdd:PHA03307 422 ASGAFYARY 430
|
|
| FHA_DgcB-like |
cd22682 |
forkhead associated (FHA) domain found in Bdellovibrio bacteriovorus GGDEF domain protein DgcB ... |
38-131 |
1.42e-07 |
|
forkhead associated (FHA) domain found in Bdellovibrio bacteriovorus GGDEF domain protein DgcB and similar proteins; DgcB is a GGDEF enzyme that produces cyclic-di-GMP in response to an unknown stimulus. It appends the C-terminal GGDEF enzymatic domain with an N-terminal forkhead-associated (FHA) domain that acts as a consensus phosphopeptide sensor. The GGDEF and sensory FHA domains form an asymmetrical dimer.
Pssm-ID: 438734 [Multi-domain] Cd Length: 96 Bit Score: 51.37 E-value: 1.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 38 SGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAwdKAPILRDCGSLNGTQIlrPPKVLSPGVSHRLRD 117
Cdd:cd22682 6 IGPPGVGKQFPITESTIVIGRSVESQVQIDDDSVSRYHAKLAVNP--SAVSIIDLGSTNGTIV--NGKKIPKLASCDLQN 81
|
90
....*....|....
gi 2462492653 118 QELILFADLLCQYH 131
Cdd:cd22682 82 GDQIKIGNTIFKFH 95
|
|
| BRCT_microcephalin_rpt2 |
cd17736 |
second BRCT domain of microcephalin and similar proteins; Microcephalin is a DNA damage ... |
1895-1963 |
1.49e-07 |
|
second BRCT domain of microcephalin and similar proteins; Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. It has been implicated in chromosome condensation and DNA damage induced cellular responses. It may play a role in neurogenesis and regulation of the size of the cerebral cortex. Microcephalin contains three BRCT repeats. This family corresponds to the second repeat.
Pssm-ID: 349368 [Multi-domain] Cd Length: 76 Bit Score: 50.67 E-value: 1.49e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462492653 1895 VLFTGVVDARGE---RAVLALGG-SLAGSAAE-ASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1963
Cdd:cd17736 3 LVMTSVHSEEQElleSVVKKLGGfRVEDSVTEkTTHVVVGSPRRTLNVLLGIARGCWILSPDWVLESLEAGKWL 76
|
|
| BRCT_nibrin |
cd17741 |
BRCT domain of nibrin and similar proteins; Nibrin (NBN), also termed Nijmegen breakage ... |
1908-1959 |
1.67e-07 |
|
BRCT domain of nibrin and similar proteins; Nibrin (NBN), also termed Nijmegen breakage syndrome protein 1 (NBS1), or cell cycle regulatory protein p95, is a novel DNA double-strand break repair protein that is mutated in Nijmegen breakage syndrome. It is a component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The BRCT (Breast Cancer Suppressor Protein BRCA1, carboxy-terminal) domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo/hetero BRCT multimers, BRCT-non-BRCT interactions, and interactions within DNA strand breaks. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is absent in this group.
Pssm-ID: 349372 [Multi-domain] Cd Length: 74 Bit Score: 50.29 E-value: 1.67e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 2462492653 1908 AVLALGGSLAGSAAEAS-HLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKA 1959
Cdd:cd17741 21 IIAKLGGKVVNEWTEECtHLVMSKIKVTVKVICALISGKPIVTPEYLDALLEA 73
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
1321-1624 |
2.18e-07 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 56.54 E-value: 2.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1321 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPeSTVPIAPELPPSTSTEQPV---TPEPTSRATRGRKN 1397
Cdd:TIGR00927 103 TPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTP-ATPSRALNHYISTSGRQRVksyTPKPRGEVKSSSPT 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1398 RSSGK----TPETLVPTAPKLEPSTSTDQPvtpeptsqATRGRTNRSSVKTPETvvpTAPELQPSTSTDQPVTPEPTSQA 1473
Cdd:TIGR00927 182 QTREKvrkyTPSPLGRMVNSYAPSTFMTMP--------RSHGITPRTTVKDSEI---TATYKMLETNPSKRTAGKTTPTP 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1474 TRGRTDRSS---VKTPETVVPTAPELQASAST-DQPVTSEPTSRTT-RGRKNRSSVKTPETVV----PAAPELQPSTSTD 1544
Cdd:TIGR00927 251 LKGMTDNTPtflTREVETDLLTSPRSVVEKNTlTTPRRVESNSSTNhWGLVGKNNLTTPQGTVlehtPATSEGQVTISIM 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1545 QPVTPEPTSRATRGRTNRS-SVKTPESIVPIAP------ELQPSTSRNQLVTPE----PTSRATRCrtnrsSVKTPEPVV 1613
Cdd:TIGR00927 331 TGSSPAETKASTAAWKIRNpLSRTSAPAVRIASatfrglEKNPSTAPSTPATPRvravLTTQVHHC-----VVVKPAPAV 405
|
330
....*....|.
gi 2462492653 1614 PTAPEPHPTTS 1624
Cdd:TIGR00927 406 PTTPSPSLTTA 416
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1218-1767 |
2.80e-07 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 56.25 E-value: 2.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1218 PVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSeptYQATRGrknrssVKTPEPVVPTAPELRPstst 1297
Cdd:PRK10263 315 PITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVA---WQPVPG------PQTGEPVIAPAPEGYP---- 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1298 drpvtPKPTSRTTRSRTNMSSVKtpetvvPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPST 1377
Cdd:PRK10263 382 -----QQSQYAQPAVQYNEPLQQ------PVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAE 450
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1378 STEQPVTPEPTSRATrgrknrssgKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPT-APELQ 1456
Cdd:PRK10263 451 EQQSTFAPQSTYQTE---------QTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKrARERE 521
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1457 PSTSTDQPVtPEPtsqatrgrtdrssVKTPETVVPTAPELQASASTdqPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPE 1536
Cdd:PRK10263 522 QLAAWYQPI-PEP-------------VKEPEPIKSSLKAPSVAAVP--PVEAAAAVSPLASGVKKATLATGAAATVAAPV 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1537 LQPSTSTdqpvTPEPTSRATRG----RTNRSSVKTPESIVPIAPELqPStsrnQLVTPEPTSRATRCRTNRSSVKTPEPV 1612
Cdd:PRK10263 586 FSLANSG----GPRPQVKEGIGpqlpRPKRIRVPTRRELASYGIKL-PS----QRAAEEKAREAQRNQYDSGDQYNDDEI 656
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1613 VPTAPE----------------------PHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQ-- 1668
Cdd:PRK10263 657 DAMQQDelarqfaqtqqqrygeqyqhdvPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKAll 736
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1669 -----------SVTPEAIAQgGQSKTLRSSTVRAMPVPTTPEFQSPvttDQPISPEPITQ--PSCIKRQRAAGNPGSLAA 1735
Cdd:PRK10263 737 ddgpheplftpIVEPVQQPQ-QPVAPQQQYQQPQQPVAPQPQYQQP---QQPVAPQPQYQqpQQPVAPQPQYQQPQQPVA 812
|
570 580 590
....*....|....*....|....*....|...
gi 2462492653 1736 P-IDHKPCSAPLEPKSQASRNQRWGAVRAAESL 1767
Cdd:PRK10263 813 PqPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTL 845
|
|
| RTT107_BRCT_5 |
pfam16770 |
Regulator of Ty1 transposition protein 107 BRCT domain; This is the fifth BRCT domain of ... |
1912-1968 |
7.31e-07 |
|
Regulator of Ty1 transposition protein 107 BRCT domain; This is the fifth BRCT domain of regulator of Ty1 transposition protein 107 (RTT107). It is involved in binding phosphorylated histone H2A.
Pssm-ID: 465266 Cd Length: 91 Bit Score: 49.05 E-value: 7.31e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492653 1912 LGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEY 1968
Cdd:pfam16770 33 LGIKIVQDPSKCNHLIAPKILRTEKFLCALAFAPYILSPDFITDCLKEGKLPDEEDY 89
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1374-1782 |
7.93e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 54.79 E-value: 7.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1374 PPSTSTEQPVTPeptsraTRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAP 1453
Cdd:PHA03307 24 PPATPGDAADDL------LSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1454 ELQPSTSTDQPVTPEPTSqaTRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPA 1533
Cdd:PHA03307 98 ASPAREGSPTPPGPSSPD--PPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1534 APELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVV 1613
Cdd:PHA03307 176 LSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENEC 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1614 PtAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSV-----KTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSS- 1687
Cdd:PHA03307 256 P-LPRPAPITLPTRIWEASGWNGPSSRPGPASSSsspreRSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSe 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1688 TVRAMPVPTTPEFQSPVTTDQPisPEPITQPSCIKRQRAAGNPGSLAAPIDHKPC----SAPLEPKSQASRNQRWGAVRA 1763
Cdd:PHA03307 335 SSRGAAVSPGPSPSRSPSPSRP--PPPADPSSPRKRPRPSRAPSSPAASAGRPTRrrarAAVAGRARRRDATGRFPAGRP 412
|
410
....*....|....*....
gi 2462492653 1764 AESLTAIPEPASPQLLETP 1782
Cdd:PHA03307 413 RPSPLDAGAASGAFYARYP 431
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
943-1376 |
1.01e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 54.31 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 943 ERDTQRGEPEGGSQDQKgQASSPTPEPGVGAGDLPGPTSAPVPS-----GSQSGGRGSPVSPRRHQ-----KGLLNCKMP 1012
Cdd:PTZ00449 528 EGEEGEHEDSKESDEPK-EGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKPEFPKDPKHPKDPEepkkpKRPRSAQRP 606
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1013 PAEKASRIRAAEKVSRgdqeSPDACLPPTVPEAPAPPQKPLNSQsqkhlapppllspllpsiKPtvrktrqdgsqEAPEA 1092
Cdd:PTZ00449 607 TRPKSPKLPELLDIPK----SPKRPESPKSPKRPPPPQRPSSPE------------------RP-----------EGPKI 653
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1093 PLSSElEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPelqpst 1172
Cdd:PTZ00449 654 IKSPK-PPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLP------ 726
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1173 sTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTsqatrgRKNRSSVKTPEPVVPTAPELQP 1252
Cdd:PTZ00449 727 -RDEEFPFEPIGDPDAEQPDDIEFFTPPEEERTFFHETPADTPLPDILAEEF------KEEDIHAETGEPDEAMKRPDSP 799
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1253 STSTDQPVTSEPTYQATRGRKNRSSVKTPEpvVPTAPELRPSTSTDRPVTPKptsrTTRSRTNMSSVKTPETVVPTAPEL 1332
Cdd:PTZ00449 800 SEHEDKPPGDHPSLPKKRHRLDGLALSTTD--LESDAGRIAKDASGKIVKLK----RSKSFDDLTTVEEAEEMGAEARKI 873
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 2462492653 1333 QIS---TSTD----QPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPS 1376
Cdd:PTZ00449 874 VVDddgTEADdedtHPPEEKHKSEVRRRRPPKKPSKPKKPSKPKKPKKPDS 924
|
|
| FHA_Ki67 |
cd22673 |
forkhead associated (FHA) domain found in proliferation marker protein Ki-67 and similar ... |
32-125 |
1.07e-06 |
|
forkhead associated (FHA) domain found in proliferation marker protein Ki-67 and similar proteins; Ki-67, also called antigen identified by monoclonal antibody Ki-67, antigen KI-67, or antigen Ki67, acts as a biological surfactant to disperse mitotic chromosomes. It is required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Ki-67 binds DNA with a preference for supercoiled DNA and AT-rich DNA. It may also play a role in chromatin organization. Ki-67 contains an FHA domain at its N-terminus. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438725 [Multi-domain] Cd Length: 95 Bit Score: 48.75 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 32 GRLHIF--SGAHGPEkdFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKApILRDCGSLNGTQiLRPPKVLSP 109
Cdd:cd22673 1 GKLVVIkkDGTDGSR--FPLTKKSCTFGRDLSCDIRIQLPGVSREHCRIEVDENGKA-YLENLSTTNPTL-VNGKAIEKS 76
|
90
....*....|....*.
gi 2462492653 110 gvsHRLRDQELILFAD 125
Cdd:cd22673 77 ---AELKDGDVITIGG 89
|
|
| FHA_FhaA-like |
cd22668 |
forkhead associated (FHA) domain found in Mycobacterium tuberculosis FHA domain-containing ... |
41-100 |
1.73e-06 |
|
forkhead associated (FHA) domain found in Mycobacterium tuberculosis FHA domain-containing protein FhaA and similar proteins; FhaA regulates cell growth and peptidoglycan synthesis by binding to MviN. It may inhibit the late stages of peptidoglycan synthesis. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438720 [Multi-domain] Cd Length: 91 Bit Score: 47.85 E-value: 1.73e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462492653 41 HGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIeilAWD-KAPILRDCGSLNGTQI 100
Cdd:cd22668 7 DGSGRVYQLREGSNIIGRGSDADFRLPDTGVSRRHAEI---RWDgQVAHLTDLGSTNGTTV 64
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1171-1529 |
2.16e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 53.25 E-value: 2.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1171 STSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEP----VVPT 1246
Cdd:PHA03307 61 ACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPdlseMLRP 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1247 APELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRtnmssvktpetvv 1326
Cdd:PHA03307 141 VGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPP------------- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1327 PTAPELQISTSTDQPVTPKpTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPET 1406
Cdd:PHA03307 208 RRSSPISASASSPAPAPGR-SAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPAS 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1407 LVPTAPKLEPSTSTDQPVTPEPTSQAT--RGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVK 1484
Cdd:PHA03307 287 SSSSPRERSPSPSPSSPGSGPAPSSPRasSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPR 366
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 2462492653 1485 TPETVVPTAPELQASAST-----------DQPVTSEPTSRTTRGRKNRSSVKTPET 1529
Cdd:PHA03307 367 KRPRPSRAPSSPAASAGRptrrraraavaGRARRRDATGRFPAGRPRPSPLDAGAA 422
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1258-1838 |
2.61e-06 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 52.78 E-value: 2.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1258 QPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTsrttrsrtnMSSVKTPETVVPTAPElqisTS 1337
Cdd:PRK10263 314 APITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQP---------VPGPQTGEPVIAPAPE----GY 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1338 TDQPVTPKPTSRttrsrtnmssvKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPS 1417
Cdd:PRK10263 381 PQQSQYAQPAVQ-----------YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1418 TSTDQPVTPEPTSQATRgrtnrssvKTPETVVPTAPELQPStSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPT-APEL 1496
Cdd:PRK10263 450 EEQQSTFAPQSTYQTEQ--------TYQQPAAQEPLYQQPQ-PVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKrARER 520
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1497 QASASTDQPVtSEPtsrttrgrknrssVKTPETVVPAAPelQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAP 1576
Cdd:PRK10263 521 EQLAAWYQPI-PEP-------------VKEPEPIKSSLK--APSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAP 584
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1577 ELQPSTSRnqlvTPEPtsratrcrtnrssvKTPEPVVPTAPEPH----PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKP 1652
Cdd:PRK10263 585 VFSLANSG----GPRP--------------QVKEGIGPQLPRPKrirvPTRRELASYGIKLPSQRAAEEKAREAQRNQYD 646
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1653 VEPAASDLEpftpTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEfqspvTTDQPISPEPITQPSCIKRQRAAG---- 1728
Cdd:PRK10263 647 SGDQYNDDE----IDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAE-----DADAAAEAELARQFAQTQQQRYSGeqpa 717
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1729 --NPGSLA----APID-------HKPCSAP-LEPKSQASRNQRWGAVRAAESLTAIPEPA--SPQLLETPIHASQIQKVE 1792
Cdd:PRK10263 718 gaNPFSLDdfefSPMKallddgpHEPLFTPiVEPVQQPQQPVAPQQQYQQPQQPVAPQPQyqQPQQPVAPQPQYQQPQQP 797
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 2462492653 1793 PAGRSRFTPELQPKASQSRKRSLATMDSPP---HQKQPQRGEVSQKTVI 1838
Cdd:PRK10263 798 VAPQPQYQQPQQPVAPQPQYQQPQQPVAPQpqyQQPQQPVAPQPQDTLL 846
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
1133-1359 |
3.82e-06 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 51.73 E-value: 3.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1133 TAQPVTPKP-------TSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRS-SVKTPETVVP 1204
Cdd:PRK13914 144 TSTPVAPTQevkkettTQQAAPAAETKTEVKQTTQATTPAPKVAETKETPVVDQNATTHAVKSGDTIWAlSVKYGVSVQD 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1205 TALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVP--TAPELQPSTSTDQPVTSeptyqatrgrknRSSVKTPE 1282
Cdd:PRK13914 224 IMSWNNLSSSSIYVGQKLAIKQTANTATPKAEVKTEAPAAEkqAAPVVKENTNTNTATTE------------KKETTTQQ 291
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492653 1283 PVVPTAPelrpsTSTDRPvTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS 1359
Cdd:PRK13914 292 QTAPKAP-----TEAAKP-APAPSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGSSNNNS 362
|
|
| FHA_PP2C70-like |
cd22678 |
forkhead associated (FHA) domain found in Arabidopsis thaliana protein phosphatase 2C 70 ... |
56-122 |
4.51e-06 |
|
forkhead associated (FHA) domain found in Arabidopsis thaliana protein phosphatase 2C 70 (AtPP2C70) and similar proteins; AtPP2C70, also called kinase-associated protein phosphatase, or protein ROOT ATTENUATED GROWTH 1, dephosphorylates the serine/threonine receptor-like kinase RLK5. It may function as a signaling component in a pathway involving RLK5. It acts as a negative regulator of the CLAVATA1 signaling in plant development by binding and dephosphorylating CLAVATA1. It is also a component of a signaling pathway which mediates adaptation to NaCl stress. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438730 [Multi-domain] Cd Length: 102 Bit Score: 46.97 E-value: 4.51e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462492653 56 VGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQI-LRPPKVlsPGVSHRLRDQELIL 122
Cdd:cd22678 27 IGRIQRGDIALKDDEVSGKHARIEWNSTGSKWELVDLGSLNGTLVnGESISP--NGRPVVLSSGDVIT 92
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
911-1309 |
5.06e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 52.10 E-value: 5.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 911 PSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKGQASSPTPEPGVgagDLPGPTSAPVPSGSQS 990
Cdd:PHA03307 61 ACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTP---PPASPPPSPAPDLSEM 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 991 GGRGSPVSPRRHQKgllnckMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPeAPAPPQKPLNSQSQKHLAPPPLlspl 1070
Cdd:PHA03307 138 LRPVGSPGPPPAAS------PPAAGASPAAVASDAASSRQAALPLSSPEETAR-APSSPPAEPPPSTPPAAASPRP---- 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1071 lpsikPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAqPVTPKPTSQATRSRT 1150
Cdd:PHA03307 207 -----PRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITL-PTRIWEASGWNGPSS 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1151 NRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSvkTPETVVPTALELQPSTSTDRPVTSEPTSQATRG 1230
Cdd:PHA03307 281 RPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESS--SSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPP 358
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462492653 1231 RKNRSSVKTPEPVVPTAPelQPSTStdqpvTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRT 1309
Cdd:PHA03307 359 PADPSSPRKRPRPSRAPS--SPAAS-----AGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARY 430
|
|
| FHA_Kanadaptin |
cd22677 |
forkhead associated (FHA) domain found in kanadaptin and similar proteins; Kanadaptin, also ... |
55-116 |
6.07e-06 |
|
forkhead associated (FHA) domain found in kanadaptin and similar proteins; Kanadaptin, also called human lung cancer oncogene 3 protein (HLC-3), kidney anion exchanger adapter protein, or solute carrier family 4 anion exchanger member 1 adapter protein (SLC4A1AP), is a nuclear protein widely expressed in mammalian tissues. It was originally isolated as a kidney Cl-/HCO3- anion exchanger 1 (kAE1)-binding protein. It is a highly mobile nucleocytoplasmic shuttling and multilocalizing protein. Its role in mammalian cells remains unclear. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438729 [Multi-domain] Cd Length: 106 Bit Score: 46.78 E-value: 6.07e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462492653 55 VVGRMPDCSVALPFPSISKQHAeieILAWDKAPI-------LRDCGSLNGTQILRPPkvLSPGVSHRLR 116
Cdd:cd22677 25 VFGRLPGCDVVLEHPSISRYHA---VLQYRGDADdhdggfyLYDLGSTHGTFLNKQR--IPPKQYYRLR 88
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
1242-1676 |
8.31e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 51.23 E-value: 8.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1242 PVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAP----ELRPS---TSTDRPVTPKPTsrttrsrt 1314
Cdd:PTZ00449 514 PEASGLPPKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPgpakEHKPSkipTLSKKPEFPKDP-------- 585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1315 nmssvKTPETvvPTAPElqistSTDQPVTP-KPTSRttrsrtnmSSVKNPEST-VPIAPELPPSTSTeqPVTPEPTSRAT 1392
Cdd:PTZ00449 586 -----KHPKD--PEEPK-----KPKRPRSAqRPTRP--------KSPKLPELLdIPKSPKRPESPKS--PKRPPPPQRPS 643
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1393 RGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSq 1472
Cdd:PTZ00449 644 SPERPEGPKIIKSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLP- 722
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1473 ATRGRTDRSSVKTPETvvPTAPElqasaSTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPept 1552
Cdd:PTZ00449 723 PKLPRDEEFPFEPIGD--PDAEQ-----PDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEEDIHAETGEPDEA--- 792
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1553 srATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATR---------CRTNRSSVKTPEPVVPTAPEPHP-- 1621
Cdd:PTZ00449 793 --MKRPDSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTDLESDAGRiakdasgkiVKLKRSKSFDDLTTVEEAEEMGAea 870
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492653 1622 ---------TTSTDQPVTP---KLTSRATRRKTNRSSVKTPKPVEPAasdlEPFTPtDQSVTPEAIA 1676
Cdd:PTZ00449 871 rkivvdddgTEADDEDTHPpeeKHKSEVRRRRPPKKPSKPKKPSKPK----KPKKP-DSAFIPSIIA 932
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
1415-1542 |
8.52e-06 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 51.25 E-value: 8.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1415 EPSTSTDQPVTPEPTSQATrgrtnrssvkTPETVVPTAPELQPSTsTDQPVTPEPTSQATRGrTDRSSVKTPETVVPTAP 1494
Cdd:NF033875 49 QPGTTTVQPDNPDPQSGSE----------TPKTAVSEEATVQKDT-TSQPTKVEEVASEKNG-AEQSSATPNDTTNAQQP 116
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2462492653 1495 ELQASAST-DQPVTSEPTSRTTRGRknrssvktPETVVPAAPELQPSTS 1542
Cdd:NF033875 117 TVGAEKSAqEQPVVSPETTNEPLGQ--------PTEVAPAENEANKSTS 157
|
|
| BRCT_p53bp1_rpt1 |
cd17745 |
first (central) BRCT domain in p53-binding protein 1 (p53BP1) and similar proteins; p53BP1, ... |
1926-1960 |
8.65e-06 |
|
first (central) BRCT domain in p53-binding protein 1 (p53BP1) and similar proteins; p53BP1, also termed 53BP1, or TP53-binding protein 1 (TP53BP1) , is a double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. TP53BP1 contains two tandem BRCT repeats. This family also includes Schizosaccharomyces pombe Crb2, which is a checkpoint mediator required for the cellular response to DNA damage. This model corresponds to the first BRCT domain.
Pssm-ID: 349376 [Multi-domain] Cd Length: 99 Bit Score: 46.15 E-value: 8.65e-06
10 20 30
....*....|....*....|....*....|....*
gi 2462492653 1926 LVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1960
Cdd:cd17745 64 LIADSPSRTPKYLQALALGIPCVSHKWILDCIEAG 98
|
|
| FHA_PS1-like |
cd22691 |
forkhead associated (FHA) domain found in Arabidopsis thaliana Protein PARALLEL SPINDLE 1 (PS1) ... |
55-98 |
1.03e-05 |
|
forkhead associated (FHA) domain found in Arabidopsis thaliana Protein PARALLEL SPINDLE 1 (PS1) and similar proteins; PS1 is an FHA domain-containing protein required for normal spindle orientation at male meiosis II and normal formation of tetrad of microspores. It is not involved in female meiosis. Mutations in PS1 lead to the production of diploid pollen grains. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438743 [Multi-domain] Cd Length: 113 Bit Score: 46.64 E-value: 1.03e-05
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 2462492653 55 VVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGT 98
Cdd:cd22691 32 VVGRHPDCDIVLDHPSISRFHLEIRIIPSRRKITLTDLSSVHGT 75
|
|
| FHA_ArnA-like |
cd22680 |
forkhead associated (FHA) domain found in Sulfolobus Acidocaldarius FHA domain-containing ... |
34-110 |
1.41e-05 |
|
forkhead associated (FHA) domain found in Sulfolobus Acidocaldarius FHA domain-containing protein ArnA and similar proteins; ArnA is an FHA domain-containing protein from Sulfolobus acidocaldarius that was shown to strongly interact with ArnB, a von Willebrand domain-containing protein. They act synergistically and negatively to modulate motility. ArnA is involved in regulating archaella expression in S. acidocaldarius. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438732 [Multi-domain] Cd Length: 96 Bit Score: 45.41 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 34 LHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQI-----LRPPKVLS 108
Cdd:cd22680 3 LEILSSPNLTGKKFPFDFSSVSIGRDPENVIVIPDPFVSRNHARITVD--SNEIYIEDLGSTNGTFVndfkrIKGPAKLH 80
|
..
gi 2462492653 109 PG 110
Cdd:cd22680 81 PN 82
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1021-1404 |
1.69e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.17 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1021 RAAEKVSRGDQESPDACLPPTVPEAPAP-PQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELE 1099
Cdd:PHA03307 46 DSAELAAVTVVAGAAACDRFEPPTGPPPgPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPAS 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1100 PFHPkpkirtrkssrmTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTdqPVT 1179
Cdd:PHA03307 126 PPPS------------PAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSS--PPA 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1180 SEPTSQVTRGRKSRSSVKTPetvvptalELQPSTSTDRPVtSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQP 1259
Cdd:PHA03307 192 EPPPSTPPAAASPRPPRRSS--------PISASASSPAPA-PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1260 VTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRttrsRTNMSSVKTPETVVPTAPELQISTSTD 1339
Cdd:PHA03307 263 ITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSS----PRASSSSSSSRESSSSSTSSSSESSRG 338
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492653 1340 QPVTPKPTSRT--TRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTP 1404
Cdd:PHA03307 339 AAVSPGPSPSRspSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATG 405
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1189-1557 |
1.73e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.17 E-value: 1.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1189 GRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTyqA 1268
Cdd:PHA03307 38 GSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSP--D 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1269 TRGRKNRSSVKTPEPVVPTAPELR---PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPElqistSTDQPVTPK 1345
Cdd:PHA03307 116 PPPPTPPPASPPPSPAPDLSEMLRpvgSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEE-----TARAPSSPP 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1346 PTSRTTRSRTNMSSVKNPEStVPIAPELPPSTSTeqpvtPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVT 1425
Cdd:PHA03307 191 AEPPPSTPPAAASPRPPRRS-SPISASASSPAPA-----PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPIT 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1426 PEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQAtrgRTDRSSVKTPETVvpTAPELQASASTDQP 1505
Cdd:PHA03307 265 LPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP---RASSSSSSSRESS--SSSTSSSSESSRGA 339
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 2462492653 1506 VTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATR 1557
Cdd:PHA03307 340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
1112-1419 |
3.10e-05 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 49.23 E-value: 3.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1112 SSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPStSTDQPVTSEPTSQVTRGRK 1191
Cdd:PHA03369 349 KTASLTAPSRVLAAAAKVAVIAAPQTHTGPADRQRPQRPDGIPYSVPARSPMTAYPPVPQ-FCGDPGLVSPYNPQSPGTS 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1192 SRSSVKTPETVVPTALELQPSTSTDRPVTSEPT-SQATRGRKNRSSVKtpEPVVPTAPELQPSTSTDQPVTSEPTYQATR 1270
Cdd:PHA03369 428 YGPEPVGPVPPQPTNPYVMPISMANMVYPGHPQeHGHERKRKRGGELK--EELIETLKLVKKLKEEQESLAKELEATAHK 505
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1271 GRKNRSS--------VKTPEPVV---PTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVP----TAPELQIS 1335
Cdd:PHA03369 506 SEIKKIAesefknagAKTAAANIepnCSADAAAPATKRARPETKTELEAVVRFPYQIRNMESPAFVHSftstTLAAAAGQ 585
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1336 TSTDQPVTPKPTSRTTrsrTNMSSVKNPESTVpiAPELPPSTSTEQPvTPEPTSRATRGRKNRSSGKTpETLVPTAPKLE 1415
Cdd:PHA03369 586 GSDTAEALAGAIETLL---TQASAQPAGLSLP--APAVPVNASTPAS-TPPPLAPQEPPQPGTSAPSL-ETSLPQQKPVL 658
|
....
gi 2462492653 1416 PSTS 1419
Cdd:PHA03369 659 SKGA 662
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
1086-1432 |
3.43e-05 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 49.22 E-value: 3.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1086 SQEAPEAPLSSELEPFHPKPkirTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPePVVPTA 1165
Cdd:TIGR00927 76 SSDPPKSSSEMEGEMLAPQA---TVGRDEATPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTP-ATPSRA 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1166 PELQPSTSTDQPVTSepTSQVTRG-RKSRSSVKTPETVvptalelqpststdRPVTSEPtsqatRGRKNRSSVKTPEPVV 1244
Cdd:TIGR00927 152 LNHYISTSGRQRVKS--YTPKPRGeVKSSSPTQTREKV--------------RKYTPSP-----LGRMVNSYAPSTFMTM 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1245 PTAPELQP-STSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTD---------RPVTPKPTSRTTRSRT 1314
Cdd:TIGR00927 211 PRSHGITPrTTVKDSEITATYKMLETNPSKRTAGKTTPTPLKGMTDNTPTFLTREvetdlltspRSVVEKNTLTTPRRVE 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1315 NMSS-----------VKTPETVV----PTAPELQISTSTDQPVTPKptsrTTRSRTNMSSVKNPES-----TVPIAP--- 1371
Cdd:TIGR00927 291 SNSStnhwglvgknnLTTPQGTVlehtPATSEGQVTISIMTGSSPA----ETKASTAAWKIRNPLSrtsapAVRIASatf 366
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462492653 1372 ---ELPPSTSTEQPVTPEPTSRATRgRKNRSSGKTPETLVPTAPklEPS-TSTDQPVTPEPTSQA 1432
Cdd:TIGR00927 367 rglEKNPSTAPSTPATPRVRAVLTT-QVHHCVVVKPAPAVPTTP--SPSlTTALFPEAPSPSPSA 428
|
|
| FHA_MEK1-like |
cd22670 |
forkhead associated (FHA) domain found in Saccharomyces cerevisiae meiosis-specific serine ... |
31-110 |
3.68e-05 |
|
forkhead associated (FHA) domain found in Saccharomyces cerevisiae meiosis-specific serine/threonine-protein kinase MEK1 and similar proteins; MEK1 (EC 2.7.11.1), also known as MRE4, is a meiosis-specific protein kinase required for chromosome synapsis and meiotic recombination. The recruitment and activation of MEK1 require the phosphorylation of the chromosome axis protein Hop1 at Thr318 (pT318), which is necessary for recognition by the MEK1 FHA domain. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438722 [Multi-domain] Cd Length: 105 Bit Score: 44.53 E-value: 3.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 31 VGRLHIFSGAhGPEKDFPLHLGKNV-VGRMPDCSVALPFPSISKQHAEIEILAWDK--API--LRDCgSLNGTQI----- 100
Cdd:cd22670 1 VGKLEVSSPG-STDIVLPIYKNQVItIGRSPSCDIVINDPFVSRTHCRIYSVQFDEssAPLvyVEDL-SSNGTYLngkli 78
|
90
....*....|.
gi 2462492653 101 -LRPPKVLSPG 110
Cdd:cd22670 79 gRNNTVLLSDG 89
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1119-1564 |
3.88e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.83 E-value: 3.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1119 PATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSsvkt 1198
Cdd:PRK07764 390 GAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ---- 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1199 petvvPTALELQPSTSTDRPVTSEPTSQATrgrknrssvkTPEPVVPTAPELQPSTSTDQPVTSE-PTYQATRGRKNRSS 1277
Cdd:PRK07764 466 -----PAPAPAAAPEPTAAPAPAPPAAPAP----------AAAPAAPAAPAAPAGADDAATLRERwPEILAAVPKRSRKT 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1278 --VKTPEPVVPtapELRPSTSTdrpvtpkPTSRTTRSRTNMSSVKTPETVVpTApelqISTSTDQPVTPKPTSRTTRSRT 1355
Cdd:PRK07764 531 waILLPEATVL---GVRGDTLV-------LGFSTGGLARRFASPGNAEVLV-TA----LAEELGGDWQVEAVVGPAPGAA 595
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1356 NMSSVKNPESTVPI--APELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQAT 1433
Cdd:PRK07764 596 GGEGPPAPASSGPPeeAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG 675
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1434 RGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPePTSQATRGRTDRSSVKTpetvvpTAPELQASASTDQPVTSEPTSR 1513
Cdd:PRK07764 676 AAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATP-PAGQADDPAAQPPQAAQ------GASAPSPAADDPVPLPPEPDDP 748
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 2462492653 1514 TTRGRKNRSSVKTPETVVPAAP--ELQPSTSTDQPVTPEPTSRATRGRTNRSS 1564
Cdd:PRK07764 749 PDPAGAPAQPPPPPAPAPAAAPaaAPPPSPPSEEEEMAEDDAPSMDDEDRRDA 801
|
|
| FHA_AGGF1 |
cd22686 |
forkhead associated (FHA) domain found in angiogenic factor with G patch and FHA domains 1 ... |
25-132 |
2.84e-04 |
|
forkhead associated (FHA) domain found in angiogenic factor with G patch and FHA domains 1 (AGGF1) and similar proteins; AGGF1, also called angiogenic factor VG5Q, or G patch domain-containing protein 7 (GPATC7), or vasculogenesis gene on 5q protein, is an angiogenic factor involved in vascular development, angiogenesis, specification of hemangioblasts, and differentiation of veins. It promotes angiogenesis and the proliferation of endothelial cells. It inhibits inflammatory effect and preserve vascular integrity in non-nervous system diseases. Mutated AGGF1 causes susceptibility to Klippel-Trenaunay syndrome, a vascular disorder. Increased AGGF1 expression is associated with tumor angiogenesis. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438738 [Multi-domain] Cd Length: 123 Bit Score: 42.65 E-value: 2.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 25 RCNVEPVGRLHIFS--GAhgpekdfplhlgknVVGRMPDCSVALPFP--SISKQHAEIEILAWDKAPILRDCGS-----L 95
Cdd:cd22686 11 ESPSLQVGSLFIVTatGA--------------TIGREKDHGHTIRIPelGVSKFHAEIYYDDDEQSYTIVDLGSqngtyL 76
|
90 100 110
....*....|....*....|....*....|....*...
gi 2462492653 96 NGTQILRPPKVLSP-GVSHrlRDQELILFADLLCQYHR 132
Cdd:cd22686 77 NGVRISQPKEKSDPyPLTH--GDELKIGETTLLFHIHP 112
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
1140-1308 |
3.68e-04 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 45.42 E-value: 3.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1140 KPTSQATRSRTNRSSVKTPEPVVPT--APELQPSTSTDQPVTSEPTSQVT---RGRKSRSSVKTPETVVPTALELQPSTS 1214
Cdd:pfam05539 167 EPKTAVTTSKTTSWPTEVSHPTYPSqvTPQSQPATQGHQTATANQRLSSTepvGTQGTTTSSNPEPQTEPPPSQRGPSGS 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1215 TDRPVTSEPTSQATRGRKNRSsvkTPEPVVPTAPElqPSTSTDQPVTSEPTYQATRGRKnrssvKTPEPVVPTAPELRPS 1294
Cdd:pfam05539 247 PQHPPSTTSQDQSTTGDGQEH---TQRRKTPPATS--NRRSPHSTATPPPTTKRQETGR-----PTPRPTATTQSGSSPP 316
|
170
....*....|....
gi 2462492653 1295 TSTDRPVTPKPTSR 1308
Cdd:pfam05539 317 HSSPPGVQANPTTQ 330
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1112-1303 |
4.68e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 4.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1112 SSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRtnrssvktpEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRK 1191
Cdd:PRK07764 600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPA---------EASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1192 SRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTD--QPVTSEPTYQAT 1269
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADdpVPLPPEPDDPPD 750
|
170 180 190
....*....|....*....|....*....|....*.
gi 2462492653 1270 RGRKNRSSVKTPEPVVPTAP--ELRPSTSTDRPVTP 1303
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPaaAPPPSPPSEEEEMA 786
|
|
| PHA03255 |
PHA03255 |
BDLF3; Provisional |
1470-1629 |
5.59e-04 |
|
BDLF3; Provisional
Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 43.74 E-value: 5.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1470 TSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPelqpstSTDQPVTP 1549
Cdd:PHA03255 27 SGSSTASAGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPVP------TTSNASTI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1550 EPTSRATRGRTNRSSVKTPESivpiapelQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPV-----------VPTAP- 1617
Cdd:PHA03255 101 NVTTKVTAQNITATEAGTGTS--------TGVTSNVTTRSSSTTSATTRITNATTLAPTLSSKgtsnatkttaeLPTVPd 172
|
170
....*....|..
gi 2462492653 1618 EPHPTTSTDQPV 1629
Cdd:PHA03255 173 ERQPSLSYGLPL 184
|
|
| FHA_EspA-like |
cd22698 |
forkhead associated (FHA) domain found in Myxococcus xanthus EspA and similar proteins; EspA ... |
42-100 |
5.83e-04 |
|
forkhead associated (FHA) domain found in Myxococcus xanthus EspA and similar proteins; EspA is a histidine protein kinase with a fork head-associated (FHA) domain at the N-terminus and a receiver domain at the C-terminus. It functions as an inhibitor of sporulation during early fruiting body development while cells are aggregating into raised mounds. EspA is part of a two-component signal transduction system that regulates the timing of sporulation initiation. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438750 [Multi-domain] Cd Length: 93 Bit Score: 40.86 E-value: 5.83e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462492653 42 GPEKDFPLHL--GKNVVGRMPDCSVALPFPSISKQHAEIEiLAWDKApILRDCGSLNGTQI 100
Cdd:cd22698 9 GSEEGKDYELdqDEFTIGRSSNNDIRLNDHSVSRHHARIV-RQGDKC-NLTDLGSTNGTFL 67
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
947-1350 |
6.57e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 45.14 E-value: 6.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 947 QRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKV 1026
Cdd:pfam03154 152 QDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLI 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1027 SRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLlpsikPTVRKTRQDGSQEAPEAPlsselePFHPKPK 1106
Cdd:pfam03154 232 QQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQM-----PPMPHSLQTGPSHMQHPV------PPQPFPL 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1107 IRTRKSSRMTPFPATSAapePHPSTSTAQpvTPKPTSQATRSRTNRSSVKTPEPVvpTAPELQPSTSTDQPVTSEPTSQV 1186
Cdd:pfam03154 301 TPQSSQSQVPPGPSPAA---PGQSQQRIH--TPPSQSQLQSQQPPREQPLPPAPL--SMPHIKPPPTTPIPQLPNPQSHK 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1187 TRGRKSRSSVKTPETVVPTALELQP--STSTDRPVTSEP-------TSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTD 1257
Cdd:pfam03154 374 HPPHLSGPSPFQMNSNLPPPPALKPlsSLSTHHPPSAHPpplqlmpQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGL 453
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1258 QPVTSEPTYqatrgrknrssvkTPEPVVPTAPELRPSTSTDRPVTPK--PTSRTTRSRTNMSSVKTPETVVPTAPELQIS 1335
Cdd:pfam03154 454 HQVPSQSPF-------------PQHPFVPGGPPPITPPSGPPTSTSSamPGIQPPSSASVSSSGPVPAAVSCPLPPVQIK 520
|
410
....*....|....*....
gi 2462492653 1336 T----STDQPVTPKPTSRT 1350
Cdd:pfam03154 521 EealdEAEEPESPPPPPRS 539
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1089-1312 |
7.38e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 44.84 E-value: 7.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1089 APEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPhPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVvPTAPEL 1168
Cdd:PRK07003 384 GARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATR-AEAPPAAPAPPATADRGDDAADGDAPVPAKANA-RASADS 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1169 QPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPEtvvPTALELQPSTSTDRPVTSEPTSQATRGRknrssvktPEPVVPTAP 1248
Cdd:PRK07003 462 RCDERDAQPPADSGSASAPASDAPPDAAFEPA---PRAAAPSAATPAAVPDARAPAAASREDA--------PAAAAPPAP 530
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462492653 1249 ELQPSTstdqPVTSEPTYQAT--------------RGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRS 1312
Cdd:PRK07003 531 EARPPT----PAAAAPAARAGgaaaaldvlrnagmRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAA 604
|
|
| Yop-YscD_cpl |
pfam16697 |
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain ... |
36-119 |
7.76e-04 |
|
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain of Yop proteins like YscD from Proteobacteria. YscD forms part of the inner membrane component of the bacterial type III secretion injectosome apparatus.
Pssm-ID: 465238 [Multi-domain] Cd Length: 94 Bit Score: 40.71 E-value: 7.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 36 IFSGAH-GpeKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILA--WdkapILRDCGSLNGT-----------QIL 101
Cdd:pfam16697 2 VLSGPHaG--AEFPLEGGRYRIGSDPDCDIVLSDKEVSRVHLKLEVDDegW----RLDDLGSGNGTlvngqrvtelgIAL 75
|
90
....*....|....*....
gi 2462492653 102 RPPKVLSPGVSH-RLRDQE 119
Cdd:pfam16697 76 RPGDRIELGQTEfCLVPAD 94
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1333-1472 |
7.82e-04 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 44.32 E-value: 7.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1333 QISTSTDQPVTPKPTSrttrSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAP 1412
Cdd:PRK12799 292 QIDTHGTVPVAAVTPS----SAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALP 367
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1413 KLEPSTSTDQPVTPEPTSQATRGRTNRSSvKTPETVVPTAPelqpststDQPVTPEPTSQ 1472
Cdd:PRK12799 368 AAEPVNMQPQPMSTTETQQSSTGNITSTA-NGPTTSLPAAP--------ASNIPVSPTSR 418
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
1370-1661 |
8.36e-04 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 44.28 E-value: 8.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1370 APELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAP-KLEPSTSTDQPVTPEPTSQAT--RGRTNRSSVKTPE 1446
Cdd:pfam04747 189 APAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAAPaSVEQVVEQPKVVTEEPHQQAApqEKKNKKNKRKSES 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1447 TVVPTAPE--LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTsrTTRGRKNRSSV 1524
Cdd:pfam04747 269 ENVPAASEtpVEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLDFV--TAKEEPKDEPA 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1525 KTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKT------PESIVPIAPELQPSTSRNQLVTPEPTSRATR 1598
Cdd:pfam04747 347 ETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDKKKSESekvteqPVESAPAPPQVEQVVETTPPASENKKKNKKD 426
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462492653 1599 CRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLE 1661
Cdd:pfam04747 427 KKKSESEKAVEEPVQAAPSSKKPTADDNMDFLDFVTAKPDKSESVEEHIAAPMIVEPAHADEE 489
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1443-1664 |
1.10e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 44.15 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1443 KTPETVVPTAPELQPSTSTDQPVTPEPTSQATRG---RTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTrgrk 1519
Cdd:PLN03209 337 DGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPlspYTAYEDLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDV---- 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1520 nrSSVKTPETVVPAAPELQPSTSTDQPVTP--------EPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPE 1591
Cdd:PLN03209 413 --VPSPGSASNVPEVEPAQVEAKKTRPLSPyaryedlkPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPP 490
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462492653 1592 PT-SRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPvepaaSDLEPFT 1664
Cdd:PLN03209 491 PAnMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQPKP-----RPLSPYT 559
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
1252-1452 |
1.29e-03 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 43.64 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1252 PSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPelRPSTSTDRPVTPK-PTSRTTRSR----------------- 1313
Cdd:PRK13914 147 PVAPTQEVKKETTTQQAAPAAETKTEVKQTTQATTPAP--KVAETKETPVVDQnATTHAVKSGdtiwalsvkygvsvqdi 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1314 ---TNMSS--------VKTPETVVPTAPELQisTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE-- 1380
Cdd:PRK13914 225 mswNNLSSssiyvgqkLAIKQTANTATPKAE--VKTEAPAAEKQAAPVVKENTNTNTATTEKKETTTQQQTAPKAPTEaa 302
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462492653 1381 QPvTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTA 1452
Cdd:PRK13914 303 KP-APAPSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGSSNNNSNSSASAIIAEA 373
|
|
| FHA_Cep170 |
cd22704 |
forkhead associated (FHA) domain found in the centrosomal protein of 170 kDa protein (Cep170) ... |
56-98 |
1.31e-03 |
|
forkhead associated (FHA) domain found in the centrosomal protein of 170 kDa protein (Cep170) family; The Cep170 family includes Cep170 and Cep170B. Cep170, also called Cep170A, KARP-1-binding protein, or KARP1-binding protein, is a protein that localizes to centrosomes as well as spindle microtubules and plays a role in microtubule organization and microtubule assembly. It is required for centriole subdistal appendage assembly. Cep170 is phosphorylated during M phase and interacts with Polo-like kinase 1 (Plk1). Cep170B, also called centrosomal protein 170B, plays a role in microtubule organization. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438756 [Multi-domain] Cd Length: 102 Bit Score: 40.00 E-value: 1.31e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 2462492653 56 VGRmPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGT 98
Cdd:cd22704 21 VGR-EDCDLILQSRSVDKQHAVITYDQIDNEFKIKDLGSLNGT 62
|
|
| DUF4775 |
pfam16001 |
Domain of unknown function (DUF4775); This family of proteins is functionally uncharacterized. ... |
1189-1512 |
1.40e-03 |
|
Domain of unknown function (DUF4775); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 308 and 484 amino acids in length.
Pssm-ID: 406411 [Multi-domain] Cd Length: 456 Bit Score: 43.57 E-value: 1.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1189 GRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRS-SVKTPEPVVPTAPELQPSTSTDQPV-----TS 1262
Cdd:pfam16001 30 GRRTRSSTRGTPTRSAETVTPPPSKKARTSPATATKSSGGKGRGARKlDVGAEEPVEQETKKKKKVQNEPEAKeekekVS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1263 EPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPET-VVPTAPE-LQISTSTDQ 1340
Cdd:pfam16001 110 EPVKGKPAAKKEKKEEKKQKKKEADEKEVVEEKEKEDKEEEKTETKETDAKTAESKDQPDGVgQLPAVAEeKQNHVDEDK 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1341 PVTPKPTSR------TTRSRTNMSSVKNPEST-VPIAPELPPST------STEQPVTPEPTSRATRGRKNRSSGKTPETL 1407
Cdd:pfam16001 190 PETEEPEEKektpeeVAKAEEPPKTSENGAATdTPAAVPESESAmevdeeEKLQENTPQATADAPSDDKAVPDIKVEEKV 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1408 VPTAPKLEPSTSTDQPV---TPEPTSQATrgrTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVK 1484
Cdd:pfam16001 270 AAVSESSEEPKETSEPAkepTPEPMEVDS---SSKGSSDTAQVDTPVKEVVPAAPATESAVAAESTEASNSNNEVVEVAT 346
|
330 340
....*....|....*....|....*...
gi 2462492653 1485 TPETVVPTAPELQASASTDQPVTSEPTS 1512
Cdd:pfam16001 347 EVKEDVPEVPPKEAESSEEPAKEAESTT 374
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1413-1554 |
1.48e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 43.17 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1413 KLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPT 1492
Cdd:PRK12799 286 KATGLKQIDTHGTVPVAAVTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVA 365
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462492653 1493 APELQASASTDQPVTSEPTSRTTRGRKNRSSvKTPETVVPAAPelqpststDQPVTPEPTSR 1554
Cdd:PRK12799 366 LPAAEPVNMQPQPMSTTETQQSSTGNITSTA-NGPTTSLPAAP--------ASNIPVSPTSR 418
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1076-1482 |
1.53e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.82 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1076 PTVRKTRQDGSQEAPEAPlsselEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSV 1155
Cdd:PRK07764 418 AAAAAPAPAAAPQPAPAP-----APAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA 492
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1156 KTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVV----PTALELQPSTSTDR-----PVTSEPTSQ 1226
Cdd:PRK07764 493 APAAPAAPAAPAGADDAATLRERWPEILAAVPKRSRKTWAILLPEATVlgvrGDTLVLGFSTGGLArrfasPGNAEVLVT 572
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1227 ATRGRKNRssVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRgrknrssvktpepvvPTAPElrpstSTDRPVTPKPT 1306
Cdd:PRK07764 573 ALAEELGG--DWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAAR---------------PAAPA-----APAAPAAPAPA 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1307 SRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSrtnmssvknPESTVPIAPELPPSTSTEQPVTPE 1386
Cdd:PRK07764 631 GAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAA---------PAAPPPAPAPAAPAAPAGAAPAQP 701
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1387 PTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTD--QPVTPEPTSQATRGRTNRSSVKTPETVVPTAP--ELQPSTSTD 1462
Cdd:PRK07764 702 APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADdpVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPaaAPPPSPPSE 781
|
410 420
....*....|....*....|
gi 2462492653 1463 QPVTPEPTSQATRGRTDRSS 1482
Cdd:PRK07764 782 EEEMAEDDAPSMDDEDRRDA 801
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1103-1217 |
1.90e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 43.17 E-value: 1.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1103 PKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEP 1182
Cdd:PRK12799 304 VTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQPQPMSTTE 383
|
90 100 110
....*....|....*....|....*....|....*.
gi 2462492653 1183 TSQVTRGrKSRSSVKTPETVVPTALELQ-PSTSTDR 1217
Cdd:PRK12799 384 TQQSSTG-NITSTANGPTTSLPAAPASNiPVSPTSR 418
|
|
| COG3456 |
COG3456 |
Predicted component of the type VI protein secretion system, contains a FHA domain [Signal ... |
55-126 |
1.99e-03 |
|
Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442679 [Multi-domain] Cd Length: 402 Bit Score: 42.83 E-value: 1.99e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462492653 55 VVGRMPDCSVALPFPS--ISKQHAEIEILawDKAPILRDCgSLNGTQILRPPKVLSPGVSHRLRDQELILFADL 126
Cdd:COG3456 29 TIGRSADCDWVLPDPDrsVSRRHAEIRFR--DGAFCLTDL-STNGTFLNGSDHPLGPGRPVRLRDGDRLRIGDY 99
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1036-1547 |
2.08e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.54 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1036 ACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELE-PFHPKPKIRTRKSSR 1114
Cdd:PRK10263 335 APVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQqPVQPQQPYYAPAAEQ 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1115 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTP-----------EPVVPTAPELQPStSTDQPVTSEPT 1183
Cdd:PRK10263 415 PAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPqstyqteqtyqQPAAQEPLYQQPQ-PVEQQPVVEPE 493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1184 SQVTRGRKSRSSVKTPETVVPT-ALELQPSTSTDRPVtSEPtsqatrgrknrssVKTPEPVVPTAPelQPSTSTDQPVTS 1262
Cdd:PRK10263 494 PVVEETKPARPPLYYFEEVEEKrAREREQLAAWYQPI-PEP-------------VKEPEPIKSSLK--APSVAAVPPVEA 557
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1263 EPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTS-TDRPVT--------PKPTSRTTRSRTNMSS--VKTPETVV----- 1326
Cdd:PRK10263 558 AAAVSPLASGVKKATLATGAAATVAAPVFSLANSgGPRPQVkegigpqlPRPKRIRVPTRRELASygIKLPSQRAaeeka 637
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1327 ------PTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSS 1400
Cdd:PRK10263 638 reaqrnQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPA 717
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1401 GKTPETL--------------VPTAPKLEPS-----TSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQpstST 1461
Cdd:PRK10263 718 GANPFSLddfefspmkallddGPHEPLFTPIvepvqQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQ---QP 794
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1462 DQPVTPEPTSQATRGRT-DRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSS-VKTPETVVPAAPELQP 1539
Cdd:PRK10263 795 QQPVAPQPQYQQPQQPVaPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRpLHKPTTPLPSLDLLTP 874
|
....*...
gi 2462492653 1540 STSTDQPV 1547
Cdd:PRK10263 875 PPSEVEPV 882
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1382-1513 |
2.14e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.78 E-value: 2.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1382 PVTPEPTSRATrgrkNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTST 1461
Cdd:PRK12799 300 PVAAVTPSSAV----TQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQ 375
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2462492653 1462 DQPVTPEPTSQATRGRTDRSSvKTPETVVPTAPELQASAStdqpvtsePTSR 1513
Cdd:PRK12799 376 PQPMSTTETQQSSTGNITSTA-NGPTTSLPAAPASNIPVS--------PTSR 418
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1293-1542 |
2.24e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 42.99 E-value: 2.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1293 PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTS-RTTRSRTNMSSVKNPESTVPIap 1371
Cdd:PLN03209 312 PLTPMEELLAKIPSQRVPPKESDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVpRPLSPYTAYEDLKPPTSPIPT-- 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1372 elPPSTSTEQPVTPEPTSRATRGRKNRSSGKT---PETLVPTAPK-----LEPSTSTDQ---PVTPEPTSQATRGRTNRS 1440
Cdd:PLN03209 390 --PPSSSPASSKSVDAVAKPAEPDVVPSPGSAsnvPEVEPAQVEAkktrpLSPYARYEDlkpPTSPSPTAPTGVSPSVSS 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1441 S---VKTPETVVPTA--PELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTT 1515
Cdd:PLN03209 468 TssvPAVPDTAPATAatDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHH 547
|
250 260
....*....|....*....|....*..
gi 2462492653 1516 RGRKNRssvktPETVVPAAPELQPSTS 1542
Cdd:PLN03209 548 AQPKPR-----PLSPYTMYEDLKPPTS 569
|
|
| FHA_SNIP1_DDL-like |
cd22676 |
forkhead associated (FHA) domain found in Smad nuclear-interacting protein 1 (SNIP1), FHA ... |
33-124 |
2.30e-03 |
|
forkhead associated (FHA) domain found in Smad nuclear-interacting protein 1 (SNIP1), FHA domain-containing protein DDL, and similar proteins; SNIP1 is an FHA domain-containing protein required for pre-mRNA splicing as a component of the spliceosome. It inhibits NF-kappaB signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. It is involved in microRNA (miRNA) biogenesis. SNIP1 is a regulator of the cell cycle and cyclin D1 expression and may be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. This family also includes Arabidopsis thaliana FHA domain-containing protein DDL and similar proteins. DDL, also called protein DAWDLE, is involved in the microRNA (miRNA) and short interfering RNA (siRNA) biogenesis. It may facilitate DCL1 to access or recognize primary miRNAs. DDL binds RNA non-specifically. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438728 [Multi-domain] Cd Length: 111 Bit Score: 39.59 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 33 RLHIFSGAHGPEkdfPLHLGKN---VVGRMPD-CSVALPFPSISKQHAEIEILAWDK----------APILRDCGSLNGT 98
Cdd:cd22676 2 RLYVFKGGEQLE---TIDIHRQsayLIGRDRRvADIPLDHPSCSKQHAVIQFREVEKrnegdvieniRPYIIDLGSTNGT 78
|
90 100
....*....|....*....|....*.
gi 2462492653 99 QILRPPkvLSPGVSHRLRDQELILFA 124
Cdd:cd22676 79 FLNGEK--IEPRRYYELREKDVLKFG 102
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
1101-1290 |
2.39e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.93 E-value: 2.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1101 FHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQatrsrtnrssvktPEPVVPTAPELQPSTSTDQPvtS 1180
Cdd:PRK07994 359 FHPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPP-------------PASAPQQAPAVPLPETTSQL--L 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1181 EPTSQVTRgRKSRSSVKTPETVVPTALELQPStSTDRPVTSEPTSQATrgrknrssvkTPEPVVPTAPELQPSTSTDQPV 1260
Cdd:PRK07994 424 AARQQLQR-AQGATKAKKSEPAAASRARPVNS-ALERLASVRPAPSAL----------EKAPAKKEAYRWKATNPVEVKK 491
|
170 180 190
....*....|....*....|....*....|
gi 2462492653 1261 TSEPTYQATrgRKNRSSVKTPEPVVPTAPE 1290
Cdd:PRK07994 492 EPVATPKAL--KKALEHEKTPELAAKLAAE 519
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
1452-1583 |
2.52e-03 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 43.16 E-value: 2.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1452 APEL--QPSTSTDQPVTPEPTSQATrgrtdrssvkTPETVVPTAPELQASaSTDQPVTSEPTSRTTRGRKNRSSVKTPET 1529
Cdd:NF033875 43 AAELdtQPGTTTVQPDNPDPQSGSE----------TPKTAVSEEATVQKD-TTSQPTKVEEVASEKNGAEQSSATPNDTT 111
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2462492653 1530 VVPAAPELQPSTSTDQPVTPEPTSRATRGRtnrssvktPESIVPIAPELQPSTS 1583
Cdd:NF033875 112 NAQQPTVGAEKSAQEQPVVSPETTNEPLGQ--------PTEVAPAENEANKSTS 157
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
840-1333 |
2.59e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 43.10 E-value: 2.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 840 PERQTDVTGEEELTKGKQDREQKqllaRDTQRQESDKNGESASPERDRESLKVEIETSEEIQEKQVQKQtlpskaferev 919
Cdd:PRK10811 583 GEETKPQEQPAPKAEAKPERQQD----RRKPRQNNRRDRNERRDTRDNRTRREGRENREENRRNRRQAQ----------- 647
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 920 ERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKGQASSPTPEPgvgagdlpgPTSAPVPSGSQSGGRGSPVSP 999
Cdd:PRK10811 648 QQTAETRESQQAEVTEKARTQDEQQQAPRRERQRRRNDEKRQAQQEAKAL---------NVEEQSVQETEQEERVQQVQP 718
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1000 RRHQKGLlnckmppaEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKhlapppllspllpSIKPTVR 1079
Cdd:PRK10811 719 RRKQRQL--------NQKVRIEQSVAEEAVAPVVEETVAAEPVVQEVPAPRTELVKVPLP-------------VVAQTAP 777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1080 KTRQDGSQEAPEA---PLSSELEPFHPKPKIRTRKSSR------MTPFPATSAAPEPHPSTS---TAQPVTPKPTSQATR 1147
Cdd:PRK10811 778 EQDEENNAENRDNngmPRRSRRSPRHLRVSGQRRRRYRderyptQSPMPLTVACASPEMASGkvwIRYPVVRPQDVQVEE 857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1148 SRTNRSSVKTP---EPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALElQPSTSTDRPVTSEPT 1224
Cdd:PRK10811 858 QREAEEVQVQPvvaEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIA-APVTEQPQVITESDV 936
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1225 SQATrgrknrSSVKTPEPVVPTAPE---LQPSTSTDQPVTSEPTYQAtrgrknrssvktpEPVVPTAPELRPSTSTDRPV 1301
Cdd:PRK10811 937 AVAQ------EVAEHAEPVVEPQDEtadIEEAAETAEVVVAEPEVVA-------------QPAAPVVAEVAAEVETVTAV 997
|
490 500 510
....*....|....*....|....*....|...
gi 2462492653 1302 TPKPTSRTTRSRTNMSSVKT-PETVVPtAPELQ 1333
Cdd:PRK10811 998 EPEVAPAQVPEATVEHNHATaPMTRAP-APEYV 1029
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
1141-1714 |
2.83e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.83 E-value: 2.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1141 PTSQATRS--RTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRP 1218
Cdd:pfam03154 34 PTNEDLRSsgRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSAKRQREKGASDTEEPERATAKKSKTQEISRPNSP 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1219 VTSEPTSQATRGRKNRSSvKTPEPVVPTAPELQPSTST--DQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTS 1296
Cdd:pfam03154 114 SEGEGESSDGRSVNDEGS-SDPKDIDQDNRSTSPSIPSpqDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTT 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1297 TDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSrttrsrtnmssvknPESTVPIAPELPPS 1376
Cdd:pfam03154 193 QAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPS--------------PHPPLQPMTQPPPP 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1377 TSTEQPVTPEPTSRATRGRKNRSSGKTPETL---VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPEtvvPTAP 1453
Cdd:pfam03154 259 SQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMqhpVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQ---SQLQ 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1454 ELQPstSTDQPVTPEPTSQatrgrtdrssvktpetvvptaPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPA 1533
Cdd:pfam03154 336 SQQP--PREQPLPPAPLSM---------------------PHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPP 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1534 APELQP--STSTDQPVTPEPtsratrgrtnrssvkTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEP 1611
Cdd:pfam03154 393 PPALKPlsSLSTHHPPSAHP---------------PPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVP 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1612 VVPTAPEPHPTTSTDQPVTPKLTsratrrktnrssvkTPKPVEPAASDLEPftPTDQSVTPEAIAQGGQSKTLRSSTVRA 1691
Cdd:pfam03154 458 SQSPFPQHPFVPGGPPPITPPSG--------------PPTSTSSAMPGIQP--PSSASVSSSGPVPAAVSCPLPPVQIKE 521
|
570 580
....*....|....*....|...
gi 2462492653 1692 MPVPTTPEFQSPVTTDQPISPEP 1714
Cdd:pfam03154 522 EALDEAEEPESPPPPPRSPSPEP 544
|
|
| Chi1 |
COG3469 |
Chitinase [Carbohydrate transport and metabolism]; |
1120-1349 |
3.03e-03 |
|
Chitinase [Carbohydrate transport and metabolism];
Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 42.43 E-value: 3.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1120 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTP 1199
Cdd:COG3469 1 SSSVSTAASPTAGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1200 ETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNrSSVK 1279
Cdd:COG3469 81 TATAAAAAATSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSG-TETA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1280 TPEPVVPTAPELRPSTSTDRPVTPKPTsrttrsrtnmssvkTPETVVPTAPELQISTSTDQPVTPKPTSR 1349
Cdd:COG3469 160 TGGTTTTSTTTTTTSASTTPSATTTAT--------------ATTASGATTPSATTTATTTGPPTPGLPKH 215
|
|
| FHA_ZEP-like |
cd22702 |
forkhead associated (FHA) domain found in chloroplastic zeaxanthin epoxidase (ZEP) and similar ... |
48-123 |
3.27e-03 |
|
forkhead associated (FHA) domain found in chloroplastic zeaxanthin epoxidase (ZEP) and similar proteins; ZEP, also called protein ABA DEFICIENT 1, ABA1, protein IMPAIRED IN BABA-INDUCED STERILITY 3, protein LOW EXPRESSION OF OSMOTIC STRESS-RESPONSIVE GENES 6, or protein NON-PHOTOCHEMICAL QUENCHING 2, plays an important role in the xanthophyll cycle and abscisic acid (ABA) biosynthesis. It converts zeaxanthin into antheraxanthin and subsequently violaxanthin. ZEP is required for resistance to osmotic and drought stresses, ABA-dependent stomatal closure, seed development and dormancy, modulation of defense gene expression, and disease resistance and non-photochemical quencing (NPQ). The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438754 [Multi-domain] Cd Length: 123 Bit Score: 39.72 E-value: 3.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 48 PLHLGKN-----VVGRMPDC-----SVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQILRPP---KVLSPGVSHR 114
Cdd:cd22702 23 PIRLTRDekqpcIIGSDPHQaisgiSVVIPSPQVSELHARITCK--NGAFFLTDLGSEHGTWINDNEgrrYRAPPNFPVR 100
|
....*....
gi 2462492653 115 LRDQELILF 123
Cdd:cd22702 101 LHPSDVIEF 109
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
822-962 |
3.46e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 42.75 E-value: 3.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 822 ERVGPERGPLERETEKL-----LPERQTDVTGEEELTKGKQDREQKQLLARDTQRQE----------SDKNGESASPERD 886
Cdd:TIGR02169 194 DEKRQQLERLRREREKAeryqaLLKEKREYEGYELLKEKEALERQKEAIERQLASLEeeleklteeiSELEKRLEEIEQL 273
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462492653 887 RESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKGQA 962
Cdd:TIGR02169 274 LEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER 349
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1316-1583 |
3.80e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 42.22 E-value: 3.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1316 MSSVKTPETVVPTAPELqisTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPvtpePTSRATRGR 1395
Cdd:PLN03209 297 LSYCKVVEVIAETTAPL---TPMEELLAKIPSQRVPPKESDAADGPKPVPTKPVTPEAPSPPIEEEP----PQPKAVVPR 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1396 KNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPeLQPSTSTDQPVTP-------- 1467
Cdd:PLN03209 370 PLSPYTAYEDLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEP-AQVEAKKTRPLSPyaryedlk 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1468 EPTSQATRGRTDRSSVKTPETVVPTAPELQ-ASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQP 1546
Cdd:PLN03209 449 PPTSPSPTAPTGVSPSVSSTSSVPAVPDTApATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNE 528
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2462492653 1547 VTP----EPTSRATRGRTNRSSVKTPESIVPIAPELQPSTS 1583
Cdd:PLN03209 529 VVKvgnsAPPTALADEQHHAQPKPRPLSPYTMYEDLKPPTS 569
|
|
| PHA03255 |
PHA03255 |
BDLF3; Provisional |
1280-1465 |
3.97e-03 |
|
BDLF3; Provisional
Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 41.04 E-value: 3.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1280 TPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS 1359
Cdd:PHA03255 28 GSSTASAGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPVPTTSNASTINVTTKVT 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1360 VKNPESTvpiapelPPSTSTEQPVTPEPTSRATrgrknrsSGKTPETLVPTAPKLepststdqpvTPEPTSQAtrgrTNR 1439
Cdd:PHA03255 108 AQNITAT-------EAGTGTSTGVTSNVTTRSS-------STTSATTRITNATTL----------APTLSSKG----TSN 159
|
170 180
....*....|....*....|....*..
gi 2462492653 1440 SSVKTPEtvVPTAP-ELQPSTSTDQPV 1465
Cdd:PHA03255 160 ATKTTAE--LPTVPdERQPSLSYGLPL 184
|
|
| PHA03255 |
PHA03255 |
BDLF3; Provisional |
1391-1547 |
5.15e-03 |
|
BDLF3; Provisional
Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 40.66 E-value: 5.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1391 ATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPelqpstSTDQPVTPEPT 1470
Cdd:PHA03255 30 STASAGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPVP------TTSNASTINVT 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1471 SQATRgrtdrSSVKTPETVVPTAPELQASASTDqpvTSEPTSRTTRGRKNRSSVKTPETV-----------VPAAP-ELQ 1538
Cdd:PHA03255 104 TKVTA-----QNITATEAGTGTSTGVTSNVTTR---SSSTTSATTRITNATTLAPTLSSKgtsnatkttaeLPTVPdERQ 175
|
....*....
gi 2462492653 1539 PSTSTDQPV 1547
Cdd:PHA03255 176 PSLSYGLPL 184
|
|
| FHA_RAD53-like_rpt2 |
cd22690 |
second forkhead associated (FHA) domain found in Saccharomyces cerevisiae Serine ... |
32-127 |
5.97e-03 |
|
second forkhead associated (FHA) domain found in Saccharomyces cerevisiae Serine/threonine-protein kinase RAD53 and similar proteins; RAD53, also called CHEK2 homolog, or serine-protein kinase 1 (Spk1), is a nuclear protein kinase that phosphorylates proteins on serine, threonine, and tyrosine. It controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints and prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. It may be involved in the phosphorylation of RPH1. RAD53 contains two FHA domains. This model corresponds to the second one. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438742 [Multi-domain] Cd Length: 105 Bit Score: 38.43 E-value: 5.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 32 GRLHIFSGAHgpeKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPI---LRDCgSLNGTQILRppKVLS 108
Cdd:cd22690 2 GRLKSLNPSY---PDIELTQNTTFIGRSKDCDEEITDPRISKHHCIITRKRSGKGLDdvyVTDT-STNGTFINN--NRLG 75
|
90 100
....*....|....*....|
gi 2462492653 109 PGVSHRLRD-QELILFADLL 127
Cdd:cd22690 76 KGSQSLLQDgDEIVLIWDKN 95
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
1434-1718 |
6.32e-03 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 41.52 E-value: 6.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1434 RGRTNRSSVKTPETVVPTAPeLQPSTSTDQPVTPEPTSQAT---RGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1510
Cdd:PHA03369 340 GLKAHNEILKTASLTAPSRV-LAAAAKVAVIAAPQTHTGPAdrqRPQRPDGIPYSVPARSPMTAYPPVPQFCGDPGLVSP 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1511 TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRAT-RGRTNRSSVKtpESIVPIAPELQPSTSRNQLVT 1589
Cdd:PHA03369 419 YNPQSPGTSYGPEPVGPVPPQPTNPYVMPISMANMVYPGHPQEHGHeRKRKRGGELK--EELIETLKLVKKLKEEQESLA 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1590 PEPTSRATRCRTNRSS--------VKTPEPVV---PTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAAS 1658
Cdd:PHA03369 497 KELEATAHKSEIKKIAesefknagAKTAAANIepnCSADAAAPATKRARPETKTELEAVVRFPYQIRNMESPAFVHSFTS 576
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462492653 1659 DLEPFTPTDQSVTPEAIAqgGQSKTLrSSTVRAMPVPTTPEFQ-------SPVTTDQPISPEPITQP 1718
Cdd:PHA03369 577 TTLAAAAGQGSDTAEALA--GAIETL-LTQASAQPAGLSLPAPavpvnasTPASTPPPLAPQEPPQP 640
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1096-1268 |
6.77e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 41.48 E-value: 6.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1096 SELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTD 1175
Cdd:pfam17823 294 NPAAPMGAQAQGPIIQVSTDQPVHNTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSMIPE 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1176 QPVTSePTSQvtrgrksrssvktPETVVPTALELQPST--STDRPVTSEPTSQATRGRKNRSSvktPEPVVPTAPELQPS 1253
Cdd:pfam17823 374 VEATS-PTTQ-------------PSPLLPTQGAAGPGIllAPEQVATEATAGTASAGPTPRSS---GDPKTLAMASCQLS 436
|
170
....*....|....*.
gi 2462492653 1254 TSTDQ-PVTSEPTYQA 1268
Cdd:pfam17823 437 TQGQYlVVTTDPLTPA 452
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1428-1667 |
7.57e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 41.37 E-value: 7.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1428 PTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1507
Cdd:PRK07003 381 PAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASAD 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1508 SEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPvtPEPTSRATRGRTNRSSVKTPESIVPIAPElQPSTSRNQL 1587
Cdd:PRK07003 461 SRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAP--SAATPAAVPDARAPAAASREDAPAAAAPP-APEARPPTP 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1588 VTPEPTSRAT--------------RCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTpKPV 1653
Cdd:PRK07003 538 AAAAPAARAGgaaaaldvlrnagmRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGA-ARA 616
|
250
....*....|....
gi 2462492653 1654 EPAASDLEPFTPTD 1667
Cdd:PRK07003 617 EQAAESRGAPPPWE 630
|
|
| FHA_Rv1747-like_rpt2 |
cd22737 |
second forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ... |
56-98 |
7.76e-03 |
|
second forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ATP-binding/permease protein Rv1747 and similar proteins; Rv1747 is a putative ATP-binding cassette (ABC) transporter involved in the translocation of an unknown substrate across the membrane. It is required for normal virulent infection by M. tuberculosis. Rv1747 has a cytoplasmic regulatory module consisting of two pThr-interacting forkhead-associated (FHA) domains connected by a conformationally disordered linker with two phospho-acceptor threonines (pThr). Recruitment and phosphorylation of Rv1747 depend on the interaction between its two non-redundant FHA domains and the autophosphorylated form of serine/threonine protein kinase PknF. This model corresponds to the second FHA domain, which has a circularly permuted FHA domain fold with a conserved pThr-binding interface.
Pssm-ID: 439356 [Multi-domain] Cd Length: 93 Bit Score: 37.86 E-value: 7.76e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 2462492653 56 VGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGT 98
Cdd:cd22737 25 IGRASDNDIVIPEGSVSRHHATLVPT--PGGTQIRDLRSTNGT 65
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1538-1880 |
7.99e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.31 E-value: 7.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1538 QPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPvvptAP 1617
Cdd:PHA03307 40 QGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSS----PD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1618 EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAiaqggqsktlrsSTVRAMPVPTT 1697
Cdd:PHA03307 116 PPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQA------------ALPLSSPEETA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1698 PEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPK-SQASRNQRWGAVRAAESLTAIPEPaSP 1776
Cdd:PHA03307 184 RAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASsSDSSSSESSGCGWGPENECPLPRP-AP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1777 QLLETPIHASQIQKVE-----PAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQ--PQRGEVSQKTVIIKEEEEDTAEK 1849
Cdd:PHA03307 263 ITLPTRIWEASGWNGPssrpgPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSssSSRESSSSSTSSSSESSRGAAVS 342
|
330 340 350
....*....|....*....|....*....|.
gi 2462492653 1850 PGKEEDvvtpKPGKRKRDQAEEEPNRIPSRS 1880
Cdd:PHA03307 343 PGPSPS----RSPSPSRPPPPADPSSPRKRP 369
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
1222-1377 |
8.33e-03 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 40.80 E-value: 8.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1222 EPTSQATRGRKNRSSVKTPEPVVPT--APELQPSTSTDQPVTSEPTYQAT--RGRKNRSSVKTPEPVVPTAPELRPSTST 1297
Cdd:pfam05539 167 EPKTAVTTSKTTSWPTEVSHPTYPSqvTPQSQPATQGHQTATANQRLSSTepVGTQGTTTSSNPEPQTEPPPSQRGPSGS 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1298 DR--PVTPKPTSRTTRSrtnmSSVKTPETVVPTAPELQ---ISTSTDQPVTPKPTSR--TTRSRTNMSSVKNPESTVPIA 1370
Cdd:pfam05539 247 PQhpPSTTSQDQSTTGD----GQEHTQRRKTPPATSNRrspHSTATPPPTTKRQETGrpTPRPTATTQSGSSPPHSSPPG 322
|
....*..
gi 2462492653 1371 PELPPST 1377
Cdd:pfam05539 323 VQANPTT 329
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1369-1611 |
9.37e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 41.07 E-value: 9.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1369 IAPELPPSTSTEQPVTPEPTSRATRgrKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRG---RTNRSSVKTP 1445
Cdd:PLN03209 306 IAETTAPLTPMEELLAKIPSQRVPP--KESDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPlspYTAYEDLKPP 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1446 ETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSvKTPETVVPTAPELQA---SASTDQPVTSEPTSRTTRGRKNRS 1522
Cdd:PLN03209 384 TSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSPGSAS-NVPEVEPAQVEAKKTrplSPYARYEDLKPPTSPSPTAPTGVS 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1523 SVKTPETVVPAAPELQPSTS-TDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRT 1601
Cdd:PLN03209 463 PSVSSTSSVPAVPDTAPATAaTDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALA 542
|
250
....*....|
gi 2462492653 1602 NRSSVKTPEP 1611
Cdd:PLN03209 543 DEQHHAQPKP 552
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1042-1350 |
9.53e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 40.71 E-value: 9.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1042 VPEAPA--PPQKPLNSQSQKHLAPPPLLSPLLPsikpTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFP 1119
Cdd:pfam17823 149 ACRANAsaAPRAAIAAASAPHAASPAPRTAASS----TTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAA 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1120 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRG---------R 1190
Cdd:pfam17823 225 GTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNpaapmgaqaQ 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1191 KSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQA--------TRGRKNRSSVKTPEPVVPTA--PELQPSTSTDQPV 1260
Cdd:pfam17823 305 GPIIQVSTDQPVHNTAGEPTPSPSNTTLEPNTPKSVAstnlavvtTTKAQAKEPSASPVPVLHTSmiPEVEATSPTTQPS 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1261 TSEPTyQATRGrknrssvktpePVVPTAPELRPSTSTDRPVTPKPTSRTTrsrtnmSSVKTPETV-VPTAPELQISTSTD 1339
Cdd:pfam17823 385 PLLPT-QGAAG-----------PGILLAPEQVATEATAGTASAGPTPRSS------GDPKTLAMAsCQLSTQGQYLVVTT 446
|
330
....*....|.
gi 2462492653 1340 QPVTPKPTSRT 1350
Cdd:pfam17823 447 DPLTPALVDKM 457
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
1304-1466 |
9.64e-03 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 40.80 E-value: 9.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1304 KPTSRTTRSRTNMSSVKTPETVVPT--APELQISTSTDQPVTPKPTSRTT----RSRTNMSSVKNPESTVPIAPELPPST 1377
Cdd:pfam05539 167 EPKTAVTTSKTTSWPTEVSHPTYPSqvTPQSQPATQGHQTATANQRLSSTepvgTQGTTTSSNPEPQTEPPPSQRGPSGS 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462492653 1378 STEQPVTPEPTSrATRGRKNRSsgkTPETLVPTAPklEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQP 1457
Cdd:pfam05539 247 PQHPPSTTSQDQ-STTGDGQEH---TQRRKTPPAT--SNRRSPHSTATPPPTTKRQETGRPTPRPTATTQSGSSPPHSSP 320
|
....*....
gi 2462492653 1458 STSTDQPVT 1466
Cdd:pfam05539 321 PGVQANPTT 329
|
|
| |
