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Conserved domains on  [gi|2462499481|ref|XP_054189238|]
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protein sel-1 homolog 2 isoform X2 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11434433)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
300-457 9.57e-43

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 154.32  E-value: 9.57e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 300 QKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYF 379
Cdd:COG0790    84 EKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWY 162

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462499481 380 QKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 457
Cdd:COG0790   163 RKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
124-247 5.42e-17

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 80.74  E-value: 5.42e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 124 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 203
Cdd:COG0790   116 PQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKAL 195

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462499481 204 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:COG0790   196 EWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAE 239
TPR COG0790
TPR repeat [General function prediction only];
479-606 2.73e-13

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 69.96  E-value: 2.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 479 SLVQYALLAEMGYEVAQSNSAFILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATH 558
Cdd:COG0790    10 AAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEW 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2462499481 559 YSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAA-QTSPDA 606
Cdd:COG0790    90 FEKAAEQ-GDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAeQGDADA 137
Mplasa_alph_rch super family cl37461
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 18-128 6.90e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


The actual alignment was detected with superfamily member TIGR04523:

Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.17  E-value: 6.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481  18 IKTIKAEEHNKRQKERNVTTQVS-----VNEIKQYLSHILEQRTSSNV--------INKRENLLEKKKNQRKIRIKGIQN 84
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISqnnkiISQLNEQISQLKKELTNSESensekqreLEEKQNEIEKLKKENQSYKQEIKN 388

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462499481  85 kdiLKRNKNHLQKQAEKNftDEGDQLFKMGIKVLQQSKSQKQKE 128
Cdd:TIGR04523 389 ---LESQINDLESKIQNQ--EKLNQQKDEQIKKLQQEKELLEKE 427
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
300-457 9.57e-43

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 154.32  E-value: 9.57e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 300 QKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYF 379
Cdd:COG0790    84 EKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWY 162

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462499481 380 QKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 457
Cdd:COG0790   163 RKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
124-247 5.42e-17

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 80.74  E-value: 5.42e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 124 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 203
Cdd:COG0790   116 PQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKAL 195

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462499481 204 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:COG0790   196 EWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAE 239
TPR COG0790
TPR repeat [General function prediction only];
479-606 2.73e-13

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 69.96  E-value: 2.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 479 SLVQYALLAEMGYEVAQSNSAFILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATH 558
Cdd:COG0790    10 AAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEW 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2462499481 559 YSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAA-QTSPDA 606
Cdd:COG0790    90 FEKAAEQ-GDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAeQGDADA 137
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 569-601 1.43e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 45.21  E-value: 1.43e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2462499481 569 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 601
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAE 33
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 569-601 1.62e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 44.86  E-value: 1.62e-06
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2462499481  569 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 601
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 388-422 2.32e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 44.47  E-value: 2.32e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 2462499481  388 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 422
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 352-386 6.61e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 43.28  E-value: 6.61e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462499481 352 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 386
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 18-128 6.90e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.17  E-value: 6.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481  18 IKTIKAEEHNKRQKERNVTTQVS-----VNEIKQYLSHILEQRTSSNV--------INKRENLLEKKKNQRKIRIKGIQN 84
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISqnnkiISQLNEQISQLKKELTNSESensekqreLEEKQNEIEKLKKENQSYKQEIKN 388

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462499481  85 kdiLKRNKNHLQKQAEKNftDEGDQLFKMGIKVLQQSKSQKQKE 128
Cdd:TIGR04523 389 ---LESQINDLESKIQNQ--EKLNQQKDEQIKKLQQEKELLEKE 427
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 216-247 8.69e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 34.46  E-value: 8.69e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2462499481  216 MSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
300-457 9.57e-43

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 154.32  E-value: 9.57e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 300 QKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYF 379
Cdd:COG0790    84 EKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWY 162

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462499481 380 QKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 457
Cdd:COG0790   163 RKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
282-459 1.34e-39

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 145.84  E-value: 1.34e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 282 WDIYQYYKFLAERGDVQIQKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLL 361
Cdd:COG0790    30 AAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRG-VPKDYEKALEWFEKAAEQGDAEAQYNLGLM 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 362 YFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVV 441
Cdd:COG0790   109 YEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVP 188

                         170
                  ....*....|....*...
gi 2462499481 442 RSCRTAVELYKGVCELGH 459
Cdd:COG0790   189 KDPAKALEWYRKAAEQGD 206
TPR COG0790
TPR repeat [General function prediction only];
307-601 1.48e-37

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 140.06  E-value: 1.48e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 307 LKAAKAGSANAMAFIGKMYLEGNAAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 386
Cdd:COG0790    18 LAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 387 WPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKgvcelghwaekflt 466
Cdd:COG0790    98 DAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYR-------------- 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 467 ayfaykdgdidsslvqyallaemgyevaqsnsafileskkanilekekmypmalllwnRAAIQGNAFARVKIGDYHYYGY 546
Cdd:COG0790   164 ----------------------------------------------------------KAAEQGDADAQYNLGVLYENGR 185

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2462499481 547 GTKKDYQTAATHYSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 601
Cdd:COG0790   186 GVPKDPAKALEWYRKAAEQ-GDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAE 239
TPR COG0790
TPR repeat [General function prediction only];
128-418 2.81e-34

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 130.82  E-value: 2.81e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 128 EEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKALIYYT 207
Cdd:COG0790    12 AAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFE 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 208 FGSAGGNMMSQMILGYRYLSGINVLQNcevalsyykkvadyiadtfeksegvpvekvrlterpenlssnseildwdiyqy 287
Cdd:COG0790    92 KAAEQGDAEAQYNLGLMYEEGLGVPQD----------------------------------------------------- 118

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 288 ykflaergdvqIQKALHYFLKAAKAGSANAMAFIGKMYLEGNaAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKG 367
Cdd:COG0790   119 -----------YAKALEWYEKAAEQGDADAQYNLGLLYLNGE-GVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRG 186

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2462499481 368 VPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLA 418
Cdd:COG0790   187 VPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKA 237
TPR COG0790
TPR repeat [General function prediction only];
124-247 5.42e-17

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 80.74  E-value: 5.42e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 124 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 203
Cdd:COG0790   116 PQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKAL 195

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462499481 204 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:COG0790   196 EWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAE 239
TPR COG0790
TPR repeat [General function prediction only];
479-606 2.73e-13

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 69.96  E-value: 2.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 479 SLVQYALLAEMGYEVAQSNSAFILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATH 558
Cdd:COG0790    10 AAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEW 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2462499481 559 YSIAANKyHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAA-QTSPDA 606
Cdd:COG0790    90 FEKAAEQ-GDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAeQGDADA 137
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 569-601 1.43e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 45.21  E-value: 1.43e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2462499481 569 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 601
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAE 33
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 569-601 1.62e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 44.86  E-value: 1.62e-06
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2462499481  569 AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQ 601
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 388-422 2.32e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 44.47  E-value: 2.32e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 2462499481  388 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 422
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 352-386 3.51e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 44.09  E-value: 3.51e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 2462499481  352 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 386
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 352-386 6.61e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 43.28  E-value: 6.61e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462499481 352 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 386
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
TPR COG0790
TPR repeat [General function prediction only];
512-601 4.21e-05

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 45.69  E-value: 4.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481 512 KEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATHYSIAANKYHNAQAMFNLAYMYEHGLGITKDIHL 591
Cdd:COG0790     6 AAAAAAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEK 85

                          90
                  ....*....|
gi 2462499481 592 ARRLYDMAAQ 601
Cdd:COG0790    86 ALEWFEKAAE 95
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 18-128 6.90e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.17  E-value: 6.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462499481  18 IKTIKAEEHNKRQKERNVTTQVS-----VNEIKQYLSHILEQRTSSNV--------INKRENLLEKKKNQRKIRIKGIQN 84
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISqnnkiISQLNEQISQLKKELTNSESensekqreLEEKQNEIEKLKKENQSYKQEIKN 388

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2462499481  85 kdiLKRNKNHLQKQAEKNftDEGDQLFKMGIKVLQQSKSQKQKE 128
Cdd:TIGR04523 389 ---LESQINDLESKIQNQ--EKLNQQKDEQIKKLQQEKELLEKE 427
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 424-459 1.04e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 39.85  E-value: 1.04e-04
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 2462499481  424 PLAIYYLAKMYATGTGVVRSCRTAVELYKGVCELGH 459
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 388-422 1.81e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 39.04  E-value: 1.81e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462499481 388 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 422
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 315-351 2.97e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 35.61  E-value: 2.97e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2462499481  315 ANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGN 351
Cdd:smart00671   1 AEAQYNLGQMYEYGLG-VPKDLEKALEYYKKAAELGN 36
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 532-567 4.11e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 35.23  E-value: 4.11e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 2462499481  532 AFARVKIGDYHYYGYGTKKDYQTAATHYSIAANKYH 567
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 216-247 8.69e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 34.46  E-value: 8.69e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2462499481  216 MSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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