NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2462512085|ref|XP_054193973|]
View 

exopolyphosphatase PRUNE1 isoform X4 [Homo sapiens]

Protein Classification

DHHA2 domain-containing protein( domain architecture ID 10500739)

DHHA2 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DHHA2 pfam02833
DHHA2 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ...
 27-157 1.53e-17

DHHA2 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members. The domain is about 120 residues long and contains a conserved DXK motif at its amino terminus.


:

Pssm-ID: 460719  Cd Length: 124  Bit Score: 76.08  E-value: 1.53e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462512085  27 LTTEQMLRKDQKTIYRQGVKVAISAIYMDLEAFLQR--SNLLADLHAFCQAHSYDVLVAMTIFFNTHNEpvrqLAIFCPh 104
Cdd:pfam02833  11 LSAEEILRKDYKEFTMGGVKVGISQVETVDEEWLLErkDELLAALEKFAERKGLDLLVLMTTDILREGS----LLLVAG- 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462512085 105 VALQTTICEVLERSHSPPlkltpassthpnlHAYLQgNTQVSRKKLLPLLQEA 157
Cdd:pfam02833  86 GEAEELVEKAFGVALEDE-------------SLGLE-GVVSRKKQVVPLLREA 124
 
Name Accession Description Interval E-value
DHHA2 pfam02833
DHHA2 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ...
 27-157 1.53e-17

DHHA2 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members. The domain is about 120 residues long and contains a conserved DXK motif at its amino terminus.


Pssm-ID: 460719  Cd Length: 124  Bit Score: 76.08  E-value: 1.53e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462512085  27 LTTEQMLRKDQKTIYRQGVKVAISAIYMDLEAFLQR--SNLLADLHAFCQAHSYDVLVAMTIFFNTHNEpvrqLAIFCPh 104
Cdd:pfam02833  11 LSAEEILRKDYKEFTMGGVKVGISQVETVDEEWLLErkDELLAALEKFAERKGLDLLVLMTTDILREGS----LLLVAG- 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462512085 105 VALQTTICEVLERSHSPPlkltpassthpnlHAYLQgNTQVSRKKLLPLLQEA 157
Cdd:pfam02833  86 GEAEELVEKAFGVALEDE-------------SLGLE-GVVSRKKQVVPLLREA 124
 
Name Accession Description Interval E-value
DHHA2 pfam02833
DHHA2 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ...
 27-157 1.53e-17

DHHA2 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members. The domain is about 120 residues long and contains a conserved DXK motif at its amino terminus.


Pssm-ID: 460719  Cd Length: 124  Bit Score: 76.08  E-value: 1.53e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462512085  27 LTTEQMLRKDQKTIYRQGVKVAISAIYMDLEAFLQR--SNLLADLHAFCQAHSYDVLVAMTIFFNTHNEpvrqLAIFCPh 104
Cdd:pfam02833  11 LSAEEILRKDYKEFTMGGVKVGISQVETVDEEWLLErkDELLAALEKFAERKGLDLLVLMTTDILREGS----LLLVAG- 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2462512085 105 VALQTTICEVLERSHSPPlkltpassthpnlHAYLQgNTQVSRKKLLPLLQEA 157
Cdd:pfam02833  86 GEAEELVEKAFGVALEDE-------------SLGLE-GVVSRKKQVVPLLREA 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH