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Conserved domains on  [gi|2462515701|ref|XP_054195729|]
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rootletin isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
156-332 3.58e-53

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 184.86  E-value: 3.58e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRL-------------RDTEHSQDLESALIRL 222
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELllrkltleprlqrLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  223 EEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQ 302
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 2462515701  303 VVGFRRLVSEVKMFTERDLLQLGGELARTS 332
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 555-1057 2.42e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 118.12  E-value: 2.42e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  555 QLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQE 634
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  635 ELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAE 714
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  715 AGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 794
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  795 LEQEVARQGLEGSLRVAEQAQEALEQQL--------PTLRHERSQLQEQLAQLSRQLSGREQELEQARREA------QRQ 860
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEadyegfleGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAlaaalqNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  861 VEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE--GQALL 938
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtlVAARL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  939 LAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 1018
Cdd:COG1196    633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 2462515701 1019 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAE 1057
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 816-1368 1.02e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.09  E-value: 1.02e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  816 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTL 895
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  896 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEkaSLDKELMAQKLVQ 975
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE--ELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  976 AEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLL 1055
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1056 AESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEV 1135
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1136 RRLQEQArdlgKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREAL 1215
Cdd:COG1196    553 VEDDEVA----AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1216 RRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSE 1295
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462515701 1296 NTRLGRELAELQgRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLG 1368
Cdd:COG1196    709 LAEAEEERLEEE-LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1135-1927 7.37e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.52  E-value: 7.37e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1135 VRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREA 1214
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1215 LRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAV-------GKEAGELRTGLQEVERSRLEARRELQELRR 1287
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeaeleelEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1288 QMKMLDSENTRLGRELAELQGRLA-LGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRL 1366
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1367 LGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQ---RRAAEAQLGGLRSALrrg 1443
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyEAAIEAALGGRLQAV--- 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1444 lglgrapspaprpvpgspardapaegsgEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQR 1523
Cdd:TIGR02168  551 ----------------------------VVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1524 ERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARR-SVDGRLSGVQAELALQEESVRRsererratldqv 1602
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIvTLDGDLVRPGGVITGGSAKTNS------------ 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1603 atlerSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQAL 1682
Cdd:TIGR02168  671 -----SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1683 QDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHD 1762
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1763 RQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRL 1842
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1843 LQERLGSLQRALAQLEAekrEVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEkgrLDRTLTGAELELAEAQR 1922
Cdd:TIGR02168  906 LESKRSELRRELEELRE---KLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENK---IEDDEEEARRRLKRLEN 979


                   ....*
gi 2462515701 1923 QIQQL 1927
Cdd:TIGR02168  980 KIKEL 984
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 76-672 5.20e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 5.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   76 LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQAlrlepgeletqeprglvrqsVELRRQLQEEQASY 155
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL--------------------ELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQV 235
Cdd:COG1196    294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  236 NAMLREQLDQAGSANQALSEDIRKVTNDwtrcRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKM 315
Cdd:COG1196    374 LAEAEEELEELAEELLEALRAAAELAAQ----LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  316 FTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADL 395
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  396 SARVTELGLAV-----KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQL 470
Cdd:COG1196    530 IGVEAAYEAALeaalaAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  471 SGSERTADASNGSLrglsgqrtpspprrsspgrgrsprrgpspacSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLG 550
Cdd:COG1196    610 EADARYYVLGDTLL-------------------------------GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  551 TLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQ 630
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2462515701  631 AAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLE 672
Cdd:COG1196    739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
156-332 3.58e-53

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 184.86  E-value: 3.58e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRL-------------RDTEHSQDLESALIRL 222
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELllrkltleprlqrLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  223 EEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQ 302
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 2462515701  303 VVGFRRLVSEVKMFTERDLLQLGGELARTS 332
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 555-1057 2.42e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 118.12  E-value: 2.42e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  555 QLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQE 634
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  635 ELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAE 714
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  715 AGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 794
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  795 LEQEVARQGLEGSLRVAEQAQEALEQQL--------PTLRHERSQLQEQLAQLSRQLSGREQELEQARREA------QRQ 860
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEadyegfleGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAlaaalqNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  861 VEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE--GQALL 938
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtlVAARL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  939 LAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 1018
Cdd:COG1196    633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 2462515701 1019 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAE 1057
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 613-1426 8.37e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.61  E-value: 8.37e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  613 QVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQdgarvrreLERSHRQLEQLEgkRSVLAKELVEVREALSRA 692
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKAER--------YKELKAELRELE--LALLVLRLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  693 TLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGR 772
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  773 QRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQ 852
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  853 ARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGR-----TLSEEATRLRLEKEALEGSLFEVQRQLAQLEARR 927
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELeeeleELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  928 EQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASlreqrAAHEEDLQRLQREKEAAWR 1007
Cdd:TIGR02168  485 AQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIE-----AALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1008 elEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLL----AESEKQQALS-------LKESEKTALsE 1076
Cdd:TIGR02168  560 --KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkFDPKLRKALSyllggvlVVDDLDNAL-E 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1077 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNAL--TSELRDLraqreeaaaahAQEVRRLQEQARDLGKQRDSCLR 1154
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerRREIEEL-----------EEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1155 EAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERI 1234
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1235 SLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGE 1314
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1315 RAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAA 1394
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK-RSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          810       820       830
                   ....*....|....*....|....*....|..
gi 2462515701 1395 RAEAAELGLRLSAAEGRAQGLEAELARVEVQR 1426
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 816-1368 1.02e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.09  E-value: 1.02e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  816 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTL 895
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  896 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEkaSLDKELMAQKLVQ 975
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE--ELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  976 AEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLL 1055
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1056 AESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEV 1135
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1136 RRLQEQArdlgKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREAL 1215
Cdd:COG1196    553 VEDDEVA----AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1216 RRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSE 1295
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462515701 1296 NTRLGRELAELQgRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLG 1368
Cdd:COG1196    709 LAEAEEERLEEE-LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 699-1441 6.61e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 6.61e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  699 LQAEKAEVAEALtKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQ 778
Cdd:TIGR02168  207 RQAEKAERYKEL-KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  779 eatvareeqerleelrleqevarqgLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQ 858
Cdd:TIGR02168  286 -------------------------LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  859 RQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEkealegsLFEVQRQLAQLEARREQLEAEgqall 938
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSK-------VAQLELQIASLNNEIERLEAR----- 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  939 laKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 1018
Cdd:TIGR02168  409 --LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1019 QLQREqeELLARLEAEKEELSEEIAALQQERdEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRD 1098
Cdd:TIGR02168  487 LQARL--DSLERLQENLEGFSEGVKALLKNQ-SGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1099 AQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRL-------QEQARDLGKQRDSCLREAEELRTQLRLL----- 1166
Cdd:TIGR02168  564 FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVakdlvkfDPKLRKALSYLLGGVLVVDDLDNALELAkklrp 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1167 -------------------------EDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 1221
Cdd:TIGR02168  644 gyrivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1222 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGR 1301
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1302 ELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKL------QEQEGEFRTRERRLLGSLEEARG 1375
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIeslaaeIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462515701 1376 TEKQQLDHARgleLKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALR 1441
Cdd:TIGR02168  884 SLEEALALLR---SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1135-1927 7.37e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.52  E-value: 7.37e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1135 VRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREA 1214
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1215 LRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAV-------GKEAGELRTGLQEVERSRLEARRELQELRR 1287
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeaeleelEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1288 QMKMLDSENTRLGRELAELQGRLA-LGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRL 1366
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1367 LGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQ---RRAAEAQLGGLRSALrrg 1443
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyEAAIEAALGGRLQAV--- 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1444 lglgrapspaprpvpgspardapaegsgEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQR 1523
Cdd:TIGR02168  551 ----------------------------VVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1524 ERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARR-SVDGRLSGVQAELALQEESVRRsererratldqv 1602
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIvTLDGDLVRPGGVITGGSAKTNS------------ 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1603 atlerSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQAL 1682
Cdd:TIGR02168  671 -----SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1683 QDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHD 1762
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1763 RQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRL 1842
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1843 LQERLGSLQRALAQLEAekrEVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEkgrLDRTLTGAELELAEAQR 1922
Cdd:TIGR02168  906 LESKRSELRRELEELRE---KLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENK---IEDDEEEARRRLKRLEN 979


                   ....*
gi 2462515701 1923 QIQQL 1927
Cdd:TIGR02168  980 KIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-944 3.08e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.59  E-value: 3.08e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   87 QQELSRVEDLLAQSRAERD------ELAIKYNAVSERLEQ------ALRLEPGELETQEPRGLVRQSVELRRQLQEEQAS 154
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKslerqaEKAERYKELKAELRElelallVLRLEELREELEELQEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  155 YRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLL---ERSGELEQQRLRDTEHSQDLESALIRLEEE----QQ 227
Cdd:TIGR02168  265 LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQilrERLANLERQLEELEAQLEELESKLDELAEElaelEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  228 RSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELehreAAWRREEESFNAYFSNEHSRLlllwrqvvgfR 307
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV----AQLELQIASLNNEIERLEARL----------E 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  308 RLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 387
Cdd:TIGR02168  411 RLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  388 SDLDKaDLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRlqeqAALETEDGEGLQQTLRDLAQAVLSDSESG 467
Cdd:TIGR02168  491 LDSLE-RLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE----AAIEAALGGRLQAVVVENLNAAKKAIAFL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  468 VQLSgsertadasngslrglSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIH-SALHKRQLQVQDMRGRYEASQ 546
Cdd:TIGR02168  566 KQNE----------------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLvKFDPKLRKALSYLLGGVLVVD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  547 DLLGTLRKQLSDSESERRALEE--------QLQRLRDKTDGAMQAHedaQREVQRLRSANELLSREKSNLAHSLQVAQQQ 618
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDgdlvrpggVITGGSAKTNSSILER---RREIEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  619 AEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDM 698
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  699 LQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQ 778
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  779 EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQarreaq 858
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN------ 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  859 rqveALERAAREKEALAKEHAGLAVQLVAAEREGRtlsEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALL 938
Cdd:TIGR02168  941 ----LQERLSEEYSLTLEEAEALENKIEDDEEEAR---RRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLT 1013


                   ....*.
gi 2462515701  939 LAKETL 944
Cdd:TIGR02168 1014 EAKETL 1019
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1136-1694 1.83e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 92.69  E-value: 1.83e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1136 RRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSL-------GEG 1208
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIarleerrREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1209 AKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQ 1288
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1289 MKMLDSENTRLGRELAELQGRLalgERAEKEsrretlglRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLG 1368
Cdd:COG1196    395 AAELAAQLEELEEAEEALLERL---ERLEEE--------LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1369 SLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGleaelarveVQRRAAEAQLGGLRSALRRGLGLGR 1448
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG---------VKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1449 APSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRERDEL 1528
Cdd:COG1196    535 AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1529 RTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERS 1608
Cdd:COG1196    615 YYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1609 LQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQrrsLEGELQRSRLGLSDREAQAQALQDRVDS 1688
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE---EEELLEEEALEELPEPPDLEELERELER 771


                   ....*.
gi 2462515701 1689 LQRQVA 1694
Cdd:COG1196    772 LEREIE 777
PTZ00121 PTZ00121
MAEBL; Provisional
 560-1252 9.81e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.04  E-value: 9.81e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  560 ESERRALEEQLQRLRDKTDGAMQAHE----------DAQREVQRLRSANELLSREKSNLAHslqvAQQQAEELRQEREKL 629
Cdd:PTZ00121  1143 EEARKAEDAKRVEIARKAEDARKAEEarkaedakkaEAARKAEEVRKAEELRKAEDARKAE----AARKAEEERKAEEAR 1218

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  630 QAAQEELRRQRDRLEEEQEDAVQdgARvRRELERSHRQLEQLEGKRSVLAKELVEVREAlSRATLQRDMLQAEKAEVAEA 709
Cdd:PTZ00121  1219 KAEDAKKAEAVKKAEEAKKDAEE--AK-KAEEERNNEEIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKADE 1294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  710 LTKAEAGRVELELsmtKLRAEEASLQDSLSKLSalneslAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQER 789
Cdd:PTZ00121  1295 AKKAEEKKKADEA---KKKAEEAKKADEAKKKA------EEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK 1365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  790 LEELRLEQEVARQGLEGSLRVAEQAQEALEQQlptlrhERSQLQEQLAQLSRQLSGREQELEQARREAQ--RQVEALERA 867
Cdd:PTZ00121  1366 AEAAEKKKEEAKKKADAAKKKAEEKKKADEAK------KKAEEDKKKADELKKAAAAKKKADEAKKKAEekKKADEAKKK 1439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  868 AREKEAlAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEG-SLFEVQRQLAQLEARREQLEAEGQALLLAKETLTG 946
Cdd:PTZ00121  1440 AEEAKK-ADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAkKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  947 ELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQAslrEQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEE 1026
Cdd:PTZ00121  1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA---EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIE 1595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1027 LLARLEAEKeelseeiaalQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRhslatislEMERQKRDAQSRQEQD 1106
Cdd:PTZ00121  1596 EVMKLYEEE----------KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKK--------EAEEKKKAEELKKAEE 1657

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1107 RSTVNAltselrdlrAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQlrlledarDGLRRELLEAQRKLRE 1186
Cdd:PTZ00121  1658 ENKIKA---------AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA--------EELKKKEAEEKKKAEE 1720

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462515701 1187 SQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRsavKKAESERISLKLANEDKEQKLALLEE 1252
Cdd:PTZ00121  1721 LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK---KIAHLKKEEEKKAEEIRKEKEAVIEE 1783
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 87-704 1.10e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.45  E-value: 1.10e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   87 QQELSRVEDLLAQSRAERDEL------AIKYNAVSERLEQALrlepgeletqeprglVRQSVELRRQLQEEQASYRRKLQ 160
Cdd:COG1196    185 EENLERLEDILGELERQLEPLerqaekAERYRELKEELKELE---------------AELLLLKLRELEAELEELEAELE 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  161 AYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLR 240
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  241 EQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAyfsnEHSRLLLLWRQVVGFRRLVSEVKMFTERD 320
Cdd:COG1196    330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE----AEEELEELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  321 LLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVT 400
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  401 ELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLqqTLRDLAQAVLSDSESGVQLSGSERTADAS 480
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA--AYEAALEAALAAALQNIVVEDDEVAAAAI 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  481 NGSLRGLSGQRTPSPPRRSSPGRGRSPRRgpspacsdssTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSE 560
Cdd:COG1196    564 EYLKAAKAGRATFLPLDKIRARAALAAAL----------ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  561 SERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQR 640
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462515701  641 DRLEEEQEDAVQdgARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 704
Cdd:COG1196    714 EERLEEELEEEA--LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 76-672 5.20e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 5.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   76 LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQAlrlepgeletqeprglvrqsVELRRQLQEEQASY 155
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL--------------------ELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQV 235
Cdd:COG1196    294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  236 NAMLREQLDQAGSANQALSEDIRKVTNDwtrcRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKM 315
Cdd:COG1196    374 LAEAEEELEELAEELLEALRAAAELAAQ----LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  316 FTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADL 395
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  396 SARVTELGLAV-----KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQL 470
Cdd:COG1196    530 IGVEAAYEAALeaalaAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  471 SGSERTADASNGSLrglsgqrtpspprrsspgrgrsprrgpspacSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLG 550
Cdd:COG1196    610 EADARYYVLGDTLL-------------------------------GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  551 TLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQ 630
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2462515701  631 AAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLE 672
Cdd:COG1196    739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 543-1010 4.83e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 61.78  E-value: 4.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  543 EASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSL-QVAQQQAEE 621
Cdd:pfam12128  467 ENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLlHFLRKEAPD 546

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  622 LRQEREKLQAAQEELRRQRD-RLEEEQEDAVQDGARVRRELER-----SHRQLEQLEGKRSVLAKELVEVREALSRATLQ 695
Cdd:pfam12128  547 WEQSIGKVISPELLHRTDLDpEVWDGSVGGELNLYGVKLDLKRidvpeWAASEEELRERLDKAEEALQSAREKQAAAEEQ 626

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  696 RDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDslsklsALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQ 775
Cdd:pfam12128  627 LVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKD------KKNKALAERKDSANERLNSLEAQLKQLDKKHQA 700

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  776 AEQEatvareEQERLEELRLEQEVARQGLEGSLRVAE-QAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQAR 854
Cdd:pfam12128  701 WLEE------QKEQKREARTEKQAYWQVVEGALDAQLaLLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLK 774

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  855 REAQRQVEALERAAREKEALAKEHAGLAvqlvaaeregRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEA----RREQL 930
Cdd:pfam12128  775 REIRTLERKIERIAVRRQEVLRYFDWYQ----------ETWLQRRPRLATQLSNIERAISELQQQLARLIAdtklRRAKL 844

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  931 EAEGQALLLAKETLTGELAGLRQQIiatqekasldKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELE 1010
Cdd:pfam12128  845 EMERKASEKQQVRLSENLRGLRCEM----------SKLATLKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVE 914
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1505-1995 2.20e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 2.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1505 EAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARrsvdgrlSGVQAELALq 1584
Cdd:PRK02224   233 RETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER-------DDLLAEAGL- 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1585 eesvrrSERERRATLDQVATLERSLQATESELRASQEKIskmkaneTKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:PRK02224   305 ------DDADAEAVEARREELEDRDEELRDRLEECRVAA-------QAHNEEAESLREDADDLEERAEELREEAAELESE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSA---- 1740
Cdd:PRK02224   372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAllea 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1741 -----------------SLNSTRDKNLHLQKALTACEHDRQVLQERLDAArQALSEARKQSSSLGEQVQTLRGEVADLEL 1803
Cdd:PRK02224   452 gkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1804 QRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEK---------- 1873
Cdd:PRK02224   531 TIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAiadaedeier 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1874 --DRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRtLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAqqqQ 1951
Cdd:PRK02224   611 lrEKREALAELNDERRERLAEKRERKRELEAEFDEAR-IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGA---V 686

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2462515701 1952 LELQQEVERLRSAQAQTERTLEARERAHRQ--RVSTLKGQLQQELR 1995
Cdd:PRK02224   687 ENELEELEELRERREALENRVEALEALYDEaeELESMYGDLRAELR 732
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
979-1380 1.75e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 1.75e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  979 EAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEelLARLEAEKEELSEEIAALQQERDEgLLLAES 1058
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE--LETLEAEIEDLRETIAETEREREE-LAEEVR 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1059 EKQQALSLKESEKTALSEKLMGTRHSLATISL---EMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAqev 1135
Cdd:PRK02224   283 DLRERLEELEEERDDLLAEAGLDDADAEAVEArreELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAE--- 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1136 rRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREAL 1215
Cdd:PRK02224   360 -ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1216 R---RSNEELRSA-------------------------VKKAESERISLKLANEDKEQKLALLEEARTAvGKEAGELRTG 1267
Cdd:PRK02224   439 RervEEAEALLEAgkcpecgqpvegsphvetieedrerVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEER 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1268 LQEVE------RSRLEARRE-LQELRRQMKMLDSEN-------TRLGRELAELQGRLAL--GERAEKESRRETLGLRQRL 1331
Cdd:PRK02224   518 REDLEeliaerRETIEEKRErAEELRERAAELEAEAeekreaaAEAEEEAEEAREEVAElnSKLAELKERIESLERIRTL 597

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462515701 1332 LKGEASLEVMRQELQVAQRKLQEQE-------GEFRTRERRLLGSLEEARGTEKQQ 1380
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNderrerlAEKRERKRELEAEFDEARIEEARE 653
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 965-1299 2.87e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.43  E-value: 2.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  965 DKELMAQKLVQAEREAQASLREQRAAHEE-DLQRLQREKEAAWRELEAERAQLQSQLQREQEellaRLEAEKEELSEEIA 1043
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERRRKLEEAEKARQAE----MDRQAAIYAEQERM 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1044 ALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHslatisLEMERQKRDAQSRQEQDRSTVNALTSELRDlraq 1123
Cdd:pfam17380  343 AMERERELERIRQEERKRELERIRQEEIAMEISRMRELER------LQMERQQKNERVRQELEAARKVKILEEERQ---- 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1124 reeaaaahaqevRRLQEQARDLGKQRdsclREAEELRT-QLRLLEDARDglrRELLEAQRKLRESQEGREVQRQEAGELR 1202
Cdd:pfam17380  413 ------------RKIQQQKVEMEQIR----AEQEEARQrEVRRLEEERA---REMERVRLEEQERQQQVERLRQQEEERK 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1203 RSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLAL-LEEARTAVGKEAGELRTGLQEVERSRLEARRE 1281
Cdd:pfam17380  474 RKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKeMEERQKAIYEEERRREAEEERRKQQEMEERRR 553

                          330
                   ....*....|....*...
gi 2462515701 1282 LQElrrQMKMLDSENTRL 1299
Cdd:pfam17380  554 IQE---QMRKATEERSRL 568
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1517-1939 6.10e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 6.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1517 ELRSAQRERDELRTQTSALNRQLAEMEAE---RDSATSRARQLQKAVAESEEA--------RRSVDGR----------LS 1575
Cdd:pfam15921  357 ELTEARTERDQFSQESGNLDDQLQKLLADlhkREKELSLEKEQNKRLWDRDTGnsitidhlRRELDDRnmevqrlealLK 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1576 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMK----ANETKLEGDKRRLKEVLDASESRT 1651
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKmtleSSERTVSDLTASLQEKERAIEATN 516

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1652 VKLELQRRSLEGELQRSRlGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGL 1731
Cdd:pfam15921  517 AEITKLRSRVDLKLQELQ-HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL 595

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1732 TEALAQSSASLNS---TRDKNLHLQKALTACEHDRQVLQ--------ERLDAAR-------QALSE---ARKQSSSLGEQ 1790
Cdd:pfam15921  596 EKEINDRRLELQEfkiLKDKKDAKIRELEARVSDLELEKvklvnagsERLRAVKdikqerdQLLNEvktSRNELNSLSED 675

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1791 VQTLRGEVAD-----------LELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERR-------LLQERLGSLQR 1852
Cdd:pfam15921  676 YEVLKRNFRNkseemetttnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITakrgqidALQSKIQFLEE 755

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1853 ALAQLEAEKR--EVERSALRLEKDRVALRRTLDKVEREKLRSHEDtvRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQ 1930
Cdd:pfam15921  756 AMTNANKEKHflKEEKNKLSQELSTVATEKNKMAGELEVLRSQER--RLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833


                   ....*....
gi 2462515701 1931 VVVLEQSHS 1939
Cdd:pfam15921  834 SVRLKLQHT 842
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 80-630 3.22e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 3.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   80 QEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELET--QEPRGLVRQSVELRRQLQEEQASYRR 157
Cdd:pfam15921  309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEarTERDQFSQESGNLDDQLQKLLADLHK 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  158 KLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLE--RSGELEQQRLRDTEHSQDLESALIR-----LEEEQQRSA 230
Cdd:pfam15921  389 REKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEvqRLEALLKAMKSECQGQMERQMAAIQgknesLEKVSSLTA 468

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  231 SLAQVNAMLREQLDQAGSANQALSEDIRKVTnDWTRCRKELEhreaawrREEESFNAYFSNEHSRLLLLWRQVVGFRRLV 310
Cdd:pfam15921  469 QLESTKEMLRKVVEELTAKKMTLESSERTVS-DLTASLQEKE-------RAIEATNAEITKLRSRVDLKLQELQHLKNEG 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  311 SEVK-MFTERDLLQLggELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQaLLQAQLEEQLRDKVLREKDLAQQQMQSD 389
Cdd:pfam15921  541 DHLRnVQTECEALKL--QMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQ-VEKAQLEKEINDRRLELQEFKILKDKKD 617

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  390 LDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE--TEDGEGLQQTLRDLAQAV-LSDSES 466
Cdd:pfam15921  618 AKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNslSEDYEVLKRNFRNKSEEMeTTTNKL 697

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  467 GVQLSGSERTADASNGSLRGLSGqrtpspprrsspgrgrsprrgpspacSDSSTLALIHSAlhkrQLQVQDMRGRYEASQ 546
Cdd:pfam15921  698 KMQLKSAQSELEQTRNTLKSMEG--------------------------SDGHAMKVAMGM----QKQITAKRGQIDALQ 747

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  547 DLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNL-----AHSLQVAQQQAEE 621
Cdd:pfam15921  748 SKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMevaldKASLQFAECQDII 827


                   ....*....
gi 2462515701  622 LRQEREKLQ 630
Cdd:pfam15921  828 QRQEQESVR 836
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 74-874 4.24e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 4.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   74 ASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQ--EPRGLVRQSVELRRQLQEE 151
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEiaSLERSIAEKERELEDAEER 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  152 QA-------SYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGEL---------EQQRLRDTEHS-QD 214
Cdd:TIGR02169  324 LAkleaeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrdelkdYREKLEKLKREiNE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  215 LESALIRLEEE-QQRSASLAQVNAML---REQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFS 290
Cdd:TIGR02169  404 LKRELDRLQEElQRLSEELADLNAAIagiEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEK 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  291 NEHSRLLLL---------WRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAgLGLSTGLRLaesrAEAALEKQA 361
Cdd:TIGR02169  484 ELSKLQRELaeaeaqaraSEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATA-IEVAAGNRL----NNVVVEDDA 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  362 LLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVkrlekqnlekdqvnkDLTEKLEALESLrlqeqaal 441
Cdd:TIGR02169  559 VAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAV---------------DLVEFDPKYEPA-------- 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  442 etedgegLQQTLRDlaQAVLSDSESGVQLSGSERTAdASNGSLRGLSGQRTpspprrsspGRGRSPRRGPSPACSDSStl 521
Cdd:TIGR02169  616 -------FKYVFGD--TLVVEDIEAARRLMGKYRMV-TLEGELFEKSGAMT---------GGSRAPRGGILFSRSEPA-- 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  522 alihsalhkrqlQVQDMRGRyeasqdlLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELL 601
Cdd:TIGR02169  675 ------------ELQRLRER-------LEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  602 SREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRreLERSHRQLEQLEGKRSVLAKE 681
Cdd:TIGR02169  736 KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEIQAELSKLEEEVSRIEAR 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  682 LVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQ 761
Cdd:TIGR02169  814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  762 LEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRvAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 841
Cdd:TIGR02169  894 LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKG-EDEEIPEEELSLEDVQAELQRVEEEIRALEP 972

                          810       820       830
                   ....*....|....*....|....*....|...
gi 2462515701  842 QLSGREQELEQARREAQRQVEALERAAREKEAL 874
Cdd:TIGR02169  973 VNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 544-918 9.06e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 9.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  544 ASQDLLGTLRKQLSDSESERRALEEQlqrlrdktdgaMQAHEDAQRevqrlrsanelLSREKSNLAHSLQVAQQQAEELR 623
Cdd:NF012221  1539 ESSQQADAVSKHAKQDDAAQNALADK-----------ERAEADRQR-----------LEQEKQQQLAAISGSQSQLESTD 1596

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  624 QereklQAAQEELRRQRDRLEEEQEDavqdgarVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRdmlqaek 703
Cdd:NF012221  1597 Q-----NALETNGQAQRDAILEESRA-------VTKELTTLAQGLDALDSQATYAGESGDQWRNPFAGGLLDR------- 1657

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  704 aeVAEAL--TKAEAGrVELELSMTKLRAEEASLQDSLSKLSAlneslAQDKLDLNRLVAQLEEEKSALQGRQRQaeQEAT 781
Cdd:NF012221  1658 --VQEQLddAKKISG-KQLADAKQRHVDNQQKVKDAVAKSEA-----GVAQGEQNQANAEQDIDDAKADAEKRK--DDAL 1727

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  782 VAREEqerleelrleqevARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQlAQLSRQLSGREQEleqaRREAQRQV 861
Cdd:NF012221  1728 AKQNE-------------AQQAESDANAAANDAQSRGEQDASAAENKANQAQAD-AKGAKQDESDKPN----RQGAAGSG 1789

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462515701  862 EALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEatrlrlEKEALEGSLFEVQR 918
Cdd:NF012221  1790 LSGKAYSVEGVAEPGSHINPDSPAAADGRFSEGLTEQ------EQEALEGATNAVNR 1840
PRK11281 PRK11281
mechanosensitive channel MscK;
17-257 1.01e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   17 TVIQTLESS--VLCQEKGLGARDLAQDAQITSLPALIREIVTR--NLSQPESPVL---LPATEMASLLSLQEE--NQL-- 85
Cdd:PRK11281    60 LVQQDLEQTlaLLDKIDRQKEETEQLKQQLAQAPAKLRQAQAEleALKDDNDEETretLSTLSLRQLESRLAQtlDQLqn 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   86 LQQELSRVEDLL--AQSRAERDELAIKYNavSERLEQALRLEPGELETQEPrglvrQSVELRRQLQEEQA------SYRR 157
Cdd:PRK11281   140 AQNDLAEYNSQLvsLQTQPERAQAALYAN--SQRLQQIRNLLKGGKVGGKA-----LRPSQRVLLQAEQAllnaqnDLQR 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  158 KLQA--------YQ-------EGQQRQAQLVQRLQGKILQykKRCSELEQQLLE-RSGELEQQRLRDTEHSQDLESALI- 220
Cdd:PRK11281   213 KSLEgntqlqdlLQkqrdyltARIQRLEHQLQLLQEAINS--KRLTLSEKTVQEaQSQDEAARIQANPLVAQELEINLQl 290

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2462515701  221 --RLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDI 257
Cdd:PRK11281   291 sqRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQI 329
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
156-332 3.58e-53

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 184.86  E-value: 3.58e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRL-------------RDTEHSQDLESALIRL 222
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEKTSELEKTELllrkltleprlqrLEREHSADLEEALIRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  223 EEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQ 302
Cdd:pfam15035   81 EEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWRE 160

                          170       180       190
                   ....*....|....*....|....*....|
gi 2462515701  303 VVGFRRLVSEVKMFTERDLLQLGGELARTS 332
Cdd:pfam15035  161 VVAVRRQFTELKTATERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 555-1057 2.42e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 118.12  E-value: 2.42e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  555 QLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQE 634
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  635 ELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAE 714
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  715 AGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 794
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  795 LEQEVARQGLEGSLRVAEQAQEALEQQL--------PTLRHERSQLQEQLAQLSRQLSGREQELEQARREA------QRQ 860
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEadyegfleGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAlaaalqNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  861 VEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE--GQALL 938
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtlVAARL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  939 LAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 1018
Cdd:COG1196    633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 2462515701 1019 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAE 1057
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 613-1426 8.37e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.61  E-value: 8.37e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  613 QVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQdgarvrreLERSHRQLEQLEgkRSVLAKELVEVREALSRA 692
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKAER--------YKELKAELRELE--LALLVLRLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  693 TLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGR 772
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  773 QRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQ 852
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  853 ARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGR-----TLSEEATRLRLEKEALEGSLFEVQRQLAQLEARR 927
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELeeeleELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  928 EQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASlreqrAAHEEDLQRLQREKEAAWR 1007
Cdd:TIGR02168  485 AQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIE-----AALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1008 elEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLL----AESEKQQALS-------LKESEKTALsE 1076
Cdd:TIGR02168  560 --KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkFDPKLRKALSyllggvlVVDDLDNAL-E 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1077 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNAL--TSELRDLraqreeaaaahAQEVRRLQEQARDLGKQRDSCLR 1154
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerRREIEEL-----------EEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1155 EAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERI 1234
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1235 SLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGE 1314
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1315 RAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAA 1394
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK-RSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          810       820       830
                   ....*....|....*....|....*....|..
gi 2462515701 1395 RAEAAELGLRLSAAEGRAQGLEAELARVEVQR 1426
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 634-1233 1.60e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 109.26  E-value: 1.60e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  634 EELRRQRDRLEEEQEDAVQdGARVRRELERshRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 713
Cdd:COG1196    196 GELERQLEPLERQAEKAER-YRELKEELKE--LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  714 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEatvareeqerLEEL 793
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE----------LEEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  794 RLEQEVA---RQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAARE 870
Cdd:COG1196    343 EEELEEAeeeLEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  871 KEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAG 950
Cdd:COG1196    423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  951 LRQQIIATQEKASLDKELMAQKLVQAEREAQAslREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELlaR 1030
Cdd:COG1196    503 YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA--AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--P 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1031 LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTV 1110
Cdd:COG1196    579 LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1111 NALTSELRdlraqREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEG 1190
Cdd:COG1196    659 GGSLTGGS-----RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 2462515701 1191 REVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESER 1233
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1310 7.08e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.06  E-value: 7.08e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  530 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLA 609
Cdd:TIGR02168  222 LRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  610 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQedavqdgARVRRELErshRQLEQLEGKRSVLAKELVEVREAL 689
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELESKLDELAEEL-------AELEEKLE---ELKEELESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  690 SRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLA-QDKLDLNRLVAQLEEEKSA 768
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  769 LQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALE---QQLPTLRHERSQLQEQLAQLSRQLS- 844
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsEGVKALLKNQSGLSGILGVLSELISv 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  845 --GREQELEQARREAQRQ--VEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQL 920
Cdd:TIGR02168  532 deGYEAAIEAALGGRLQAvvVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  921 AQLEARREQLeaegQALLLAKETLTGELAgLRQQIIATQEKASLDKELMAQK--LVQAEREAQASLREQRAAHEEdLQRL 998
Cdd:TIGR02168  612 PKLRKALSYL----LGGVLVVDDLDNALE-LAKKLRPGYRIVTLDGDLVRPGgvITGGSAKTNSSILERRREIEE-LEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  999 QREKEAAWRELEAERAQL---QSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES--EKTA 1073
Cdd:TIGR02168  686 IEELEEKIAELEKALAELrkeLEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELeaEIEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1074 LSEKLMGTRHSLATISLEMERQKRDAQSRQEQ---DRSTVNALTSELRDLRAQREEAAAAHAQEVRRL---QEQARDLGK 1147
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEElkaLREALDELRAELTLLNEEAANLRERLESLERRIaatERRLEDLEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1148 QRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVK 1227
Cdd:TIGR02168  846 QIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1228 KAESERISLKLanedkeQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQ 1307
Cdd:TIGR02168  926 QLELRLEGLEV------RIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELK 999


                   ...
gi 2462515701 1308 GRL 1310
Cdd:TIGR02168 1000 ERY 1002
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 546-1147 8.88e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.56  E-value: 8.88e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  546 QDLLGTLRKQLSDSESER------RALEEQLQRLrdktdgamqaheDAQREVQRLRSANELLSREKSNLAHSLQVAQQQA 619
Cdd:COG1196    192 EDILGELERQLEPLERQAekaeryRELKEELKEL------------EAELLLLKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  620 EELRQEREKLQAAQEELRRQRDRLEEEQEDAvqdgARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDML 699
Cdd:COG1196    260 AELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  700 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQE 779
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  780 ATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQR 859
Cdd:COG1196    416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  860 QVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQL--EAEGQAL 937
Cdd:COG1196    496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkaAKAGRAT 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  938 LLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ 1017
Cdd:COG1196    576 FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1018 SQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKlmgtRHSLATISLEMERQKR 1097
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE----RLEEELEEEALEEQLE 731

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1098 DAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGK 1147
Cdd:COG1196    732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 816-1368 1.02e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.09  E-value: 1.02e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  816 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTL 895
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  896 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEkaSLDKELMAQKLVQ 975
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE--ELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  976 AEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLL 1055
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1056 AESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEV 1135
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1136 RRLQEQArdlgKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREAL 1215
Cdd:COG1196    553 VEDDEVA----AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1216 RRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSE 1295
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462515701 1296 NTRLGRELAELQgRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLG 1368
Cdd:COG1196    709 LAEAEEERLEEE-LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 829-1421 1.99e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 102.32  E-value: 1.99e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  829 RSQLQEQLAQLSRQ----LSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRL 904
Cdd:COG1196    195 LGELERQLEPLERQaekaERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  905 EKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKlvQAEREAQASL 984
Cdd:COG1196    275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL--EEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  985 REQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQqeRDEGLLLAESEKQQAL 1064
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE--RLERLEEELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1065 SLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARD 1144
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1145 LGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRS 1224
Cdd:COG1196    511 KAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAA 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1225 AVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRElqELRRQMKMLDSENTRLGRELA 1304
Cdd:COG1196    591 ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR--EVTLEGEGGSAGGSLTGGSRR 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1305 ELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEeargtekQQLDHA 1384
Cdd:COG1196    669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE-------ELLEEL 741

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 2462515701 1385 RGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELAR 1421
Cdd:COG1196    742 LEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 699-1441 6.61e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 6.61e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  699 LQAEKAEVAEALtKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQ 778
Cdd:TIGR02168  207 RQAEKAERYKEL-KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  779 eatvareeqerleelrleqevarqgLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQ 858
Cdd:TIGR02168  286 -------------------------LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  859 RQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEkealegsLFEVQRQLAQLEARREQLEAEgqall 938
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSK-------VAQLELQIASLNNEIERLEAR----- 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  939 laKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 1018
Cdd:TIGR02168  409 --LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1019 QLQREqeELLARLEAEKEELSEEIAALQQERdEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRD 1098
Cdd:TIGR02168  487 LQARL--DSLERLQENLEGFSEGVKALLKNQ-SGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1099 AQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRL-------QEQARDLGKQRDSCLREAEELRTQLRLL----- 1166
Cdd:TIGR02168  564 FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVakdlvkfDPKLRKALSYLLGGVLVVDDLDNALELAkklrp 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1167 -------------------------EDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 1221
Cdd:TIGR02168  644 gyrivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1222 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGR 1301
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1302 ELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKL------QEQEGEFRTRERRLLGSLEEARG 1375
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIeslaaeIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462515701 1376 TEKQQLDHARgleLKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALR 1441
Cdd:TIGR02168  884 SLEEALALLR---SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1135-1927 7.37e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.52  E-value: 7.37e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1135 VRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREA 1214
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1215 LRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAV-------GKEAGELRTGLQEVERSRLEARRELQELRR 1287
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeaeleelEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1288 QMKMLDSENTRLGRELAELQGRLA-LGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRL 1366
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1367 LGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQ---RRAAEAQLGGLRSALrrg 1443
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyEAAIEAALGGRLQAV--- 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1444 lglgrapspaprpvpgspardapaegsgEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQR 1523
Cdd:TIGR02168  551 ----------------------------VVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1524 ERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARR-SVDGRLSGVQAELALQEESVRRsererratldqv 1602
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIvTLDGDLVRPGGVITGGSAKTNS------------ 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1603 atlerSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQAL 1682
Cdd:TIGR02168  671 -----SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1683 QDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHD 1762
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1763 RQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRL 1842
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1843 LQERLGSLQRALAQLEAekrEVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEkgrLDRTLTGAELELAEAQR 1922
Cdd:TIGR02168  906 LESKRSELRRELEELRE---KLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENK---IEDDEEEARRRLKRLEN 979


                   ....*
gi 2462515701 1923 QIQQL 1927
Cdd:TIGR02168  980 KIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-944 3.08e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.59  E-value: 3.08e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   87 QQELSRVEDLLAQSRAERD------ELAIKYNAVSERLEQ------ALRLEPGELETQEPRGLVRQSVELRRQLQEEQAS 154
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKslerqaEKAERYKELKAELRElelallVLRLEELREELEELQEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  155 YRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLL---ERSGELEQQRLRDTEHSQDLESALIRLEEE----QQ 227
Cdd:TIGR02168  265 LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQilrERLANLERQLEELEAQLEELESKLDELAEElaelEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  228 RSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELehreAAWRREEESFNAYFSNEHSRLlllwrqvvgfR 307
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV----AQLELQIASLNNEIERLEARL----------E 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  308 RLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 387
Cdd:TIGR02168  411 RLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  388 SDLDKaDLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRlqeqAALETEDGEGLQQTLRDLAQAVLSDSESG 467
Cdd:TIGR02168  491 LDSLE-RLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE----AAIEAALGGRLQAVVVENLNAAKKAIAFL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  468 VQLSgsertadasngslrglSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIH-SALHKRQLQVQDMRGRYEASQ 546
Cdd:TIGR02168  566 KQNE----------------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLvKFDPKLRKALSYLLGGVLVVD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  547 DLLGTLRKQLSDSESERRALEE--------QLQRLRDKTDGAMQAHedaQREVQRLRSANELLSREKSNLAHSLQVAQQQ 618
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDgdlvrpggVITGGSAKTNSSILER---RREIEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  619 AEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDM 698
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  699 LQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQ 778
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  779 EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQarreaq 858
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN------ 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  859 rqveALERAAREKEALAKEHAGLAVQLVAAEREGRtlsEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALL 938
Cdd:TIGR02168  941 ----LQERLSEEYSLTLEEAEALENKIEDDEEEAR---RRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLT 1013


                   ....*.
gi 2462515701  939 LAKETL 944
Cdd:TIGR02168 1014 EAKETL 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1179-1992 4.86e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 94.74  E-value: 4.86e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1179 EAQRKLRESQEGREVQRQEAGELRR---SLGEGAKEREALRRSNEELRSAvkkaesERISLKLANEDKEQKLALLEEART 1255
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERqlkSLERQAEKAERYKELKAELREL------ELALLVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1256 AVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGE 1335
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1336 ASLEVMRQELQVAQRKLQEQEGEFRtrerRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGL 1415
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELE----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1416 EAELARVEVQRRAAEAQLGGLRSALRRglglgrapspaprpvpgsPARDAPAEGSGEGLNSPSTLECSPGSQPPSPgpat 1495
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKLEE------------------AELKELQAELEELEEELEELQEELERLEEAL---- 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1496 spaspdldpEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSAtsrarqlqKAVAESEEARRSVDGRLS 1575
Cdd:TIGR02168  464 ---------EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV--------KALLKNQSGLSGILGVLS 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1576 ---------GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDA 1646
Cdd:TIGR02168  527 elisvdegyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1647 SESRTVKLelqRRSLEGELQRSRLglSDREAQAQALQDRVDSLQRQVadseVKAGTLQLTVERLNGALAKVEESEGALRD 1726
Cdd:TIGR02168  607 LVKFDPKL---RKALSYLLGGVLV--VDDLDNALELAKKLRPGYRIV----TLDGDLVRPGGVITGGSAKTNSSILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1727 KVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRV 1806
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1807 EAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVE 1886
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1887 REKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQevERLRSAQA 1966
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE--SKRSELRR 915

                          810       820
                   ....*....|....*....|....*.
gi 2462515701 1967 QTERtLEARERAHRQRVSTLKGQLQQ 1992
Cdd:TIGR02168  916 ELEE-LREKLAQLELRLEGLEVRIDN 940
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1136-1694 1.83e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 92.69  E-value: 1.83e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1136 RRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSL-------GEG 1208
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIarleerrREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1209 AKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQ 1288
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1289 MKMLDSENTRLGRELAELQGRLalgERAEKEsrretlglRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLG 1368
Cdd:COG1196    395 AAELAAQLEELEEAEEALLERL---ERLEEE--------LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1369 SLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGleaelarveVQRRAAEAQLGGLRSALRRGLGLGR 1448
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG---------VKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1449 APSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRERDEL 1528
Cdd:COG1196    535 AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1529 RTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERS 1608
Cdd:COG1196    615 YYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1609 LQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQrrsLEGELQRSRLGLSDREAQAQALQDRVDS 1688
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE---EEELLEEEALEELPEPPDLEELERELER 771


                   ....*.
gi 2462515701 1689 LQRQVA 1694
Cdd:COG1196    772 LEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 518-1187 1.83e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 1.83e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  518 SSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSA 597
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  598 NELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSV 677
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  678 LAKE-------------------LVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSL 738
Cdd:TIGR02168  419 LQQEieellkkleeaelkelqaeLEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  739 SKLSALNESLAQDKLDLNRL-------------------------------------------VAQLEEEKS-------- 767
Cdd:TIGR02168  499 ENLEGFSEGVKALLKNQSGLsgilgvlselisvdegyeaaieaalggrlqavvvenlnaakkaIAFLKQNELgrvtflpl 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  768 ------ALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHER------------ 829
Cdd:TIGR02168  579 dsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpg 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  830 ---------------------SQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAA 888
Cdd:TIGR02168  659 gvitggsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL 738

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  889 EREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKEL 968
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  969 MAQKlvqaeREAQASLREQRAAHEEDLQRLQREKEAAwRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQE 1048
Cdd:TIGR02168  819 AANL-----RERLESLERRIAATERRLEDLEEQIEEL-SEDIESLAAEIEELEELIEELESELEALLNERASLEEALALL 892

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1049 RDEglllaESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAA 1128
Cdd:TIGR02168  893 RSE-----LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE 967

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462515701 1129 AAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDglrrELLEAQRKLRES 1187
Cdd:TIGR02168  968 EEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKE----DLTEAKETLEEA 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 854-1428 7.79e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.38  E-value: 7.79e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  854 RREAQRQVEALER---AAREKEALAKEHAGLAVQLVAAERegRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQL 930
Cdd:COG1196    195 LGELERQLEPLERqaeKAERYRELKEELKELEAELLLLKL--RELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  931 EAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAER--EAQASLREQRAAHEEDLQRLQREKEAAWRE 1008
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEleEELAELEEELEELEEELEELEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1009 LEAERAQLQSQLQreqeellarleaekeELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATI 1088
Cdd:COG1196    353 LEEAEAELAEAEE---------------ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1089 SLEMERQKRDAQSRQ-EQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLE 1167
Cdd:COG1196    418 RLEEELEELEEALAElEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1168 DARDGLRRELLEAQRKLRESQEGREVQ----------RQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLK 1237
Cdd:COG1196    498 EAEADYEGFLEGVKAALLLAGLRGLAGavavligveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1238 LANEDKEQKLALLEEARTAVG----------KEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQ 1307
Cdd:COG1196    578 PLDKIRARAALAAALARGAIGaavdlvasdlREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGS 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1308 GRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGL 1387
Cdd:COG1196    658 AGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 2462515701 1388 ELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRA 1428
Cdd:COG1196    738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 617-1383 1.06e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 87.05  E-value: 1.06e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  617 QQAEELRQEREKLQAAQEELRRQRDR----LEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRA 692
Cdd:TIGR02169  198 QQLERLRREREKAERYQALLKEKREYegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  693 TLQRDML--------QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEE 764
Cdd:TIGR02169  278 NKKIKDLgeeeqlrvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  765 EKSALQGRQRQAEQEAtvareeqerleelrleqevarQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLS 844
Cdd:TIGR02169  358 EYAELKEELEDLRAEL---------------------EEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQ 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  845 GREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE 924
Cdd:TIGR02169  417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAE 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  925 ARREQLEAEGQALLLAKETL----------TGELAGLRQQIIATQEKAS--------LDKELMAQKLVQAEREAQAS--- 983
Cdd:TIGR02169  497 AQARASEERVRGGRAVEEVLkasiqgvhgtVAQLGSVGERYATAIEVAAgnrlnnvvVEDDAVAKEAIELLKRRKAGrat 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  984 ---LREQRAAHEE--------------DLQRLQREKEAAWRELeaeraqLQSQLQREQEELLARLEAEKEELSEeiaalq 1046
Cdd:TIGR02169  577 flpLNKMRDERRDlsilsedgvigfavDLVEFDPKYEPAFKYV------FGDTLVVEDIEAARRLMGKYRMVTL------ 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1047 qerdEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLraqree 1126
Cdd:TIGR02169  645 ----EGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA------ 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1127 aaaahAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLG 1206
Cdd:TIGR02169  715 -----SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1207 EgaKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARtavgkeagelrtglqeversrlearrelQELR 1286
Cdd:TIGR02169  790 H--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI----------------------------QELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1287 RQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRL 1366
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ-IEKKRKR 918

                          810
                   ....*....|....*..
gi 2462515701 1367 LGSLEEARGTEKQQLDH 1383
Cdd:TIGR02169  919 LSELKAKLEALEEELSE 935
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1517-1999 1.07e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.91  E-value: 1.07e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1517 ELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERR 1596
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1597 ATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDRE 1676
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1677 AQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKAL 1756
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1757 TACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVAD-LELQRVEAEGQLQQLREVLRQRQEGEAAALNTVqk 1835
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA-- 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1836 lqDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKvEREKLRSHEDTVRLSAEKGRLDRTLTGAEL 1915
Cdd:COG1196    544 --LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAA-ALARGAIGAAVDLVASDLREADARYYVLGD 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1916 ELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVSTLKGQLQQELR 1995
Cdd:COG1196    621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700


                   ....
gi 2462515701 1996 RSSA 1999
Cdd:COG1196    701 AEEE 704
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 913-1442 1.59e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 1.59e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  913 LFEVQRQLAQLEARREQLE-----------AEGQALLLAKETLTGELAGLRQQIIATQEKAsldkelmaQKLVQAEREAQ 981
Cdd:COG1196    195 LGELERQLEPLERQAEKAEryrelkeelkeLEAELLLLKLRELEAELEELEAELEELEAEL--------EELEAELAELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  982 ASLREQRAAHEEDLQRLQrEKEAAWRELEAERAQLQSQLQREQEELlarleaekEELSEEIAALQQERDEGLLLAESEKQ 1061
Cdd:COG1196    267 AELEELRLELEELELELE-EAQAEEYELLAELARLEQDIARLEERR--------RELEERLEELEEELAELEEELEELEE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1062 QALSLKESEKTALSEKLmgtrhslatislEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQ 1141
Cdd:COG1196    338 ELEELEEELEEAEEELE------------EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1142 ARdlgkQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 1221
Cdd:COG1196    406 EE----AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1222 LRSAVKKAESERISLKLANEDKEQK----LALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENT 1297
Cdd:COG1196    482 LLEELAEAAARLLLLLEAEADYEGFlegvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1298 RLGRELAELQGRLAL--GERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARG 1375
Cdd:COG1196    562 AIEYLKAAKAGRATFlpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVT 641

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462515701 1376 TEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRR 1442
Cdd:COG1196    642 LAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 992-1758 1.67e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 1.67e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  992 EEDLQRLQREKEAA--WRELEAERAQLQSQLQREQeelLARLEAEKEELSEEIAALQQERDEgLLLAESEKQQALSLKES 1069
Cdd:TIGR02168  199 ERQLKSLERQAEKAerYKELKAELRELELALLVLR---LEELREELEELQEELKEAEEELEE-LTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1070 EKTALSEK---LMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAqevrRLQEQARDLG 1146
Cdd:TIGR02168  275 EVSELEEEieeLQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA----ELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1147 KQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAV 1226
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1227 KKAESERISLKLANEDKEQKLALLEEARtavgkeageLRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAEL 1306
Cdd:TIGR02168  431 EEAELKELQAELEELEEELEELQEELER---------LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1307 QGrLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRK-LQEQEGEFRTRERRLLGSLEEARgtekqqLDHAR 1385
Cdd:TIGR02168  502 EG-FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrLQAVVVENLNAAKKAIAFLKQNE------LGRVT 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1386 GLELKLEAARAEAAELGLRLSAAEGrAQGLEAELARVEVQ-RRAAEAQLGGLRSA--LRRGLGLGRAPSPAPRPVP--GS 1460
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDREILKNIEG-FLGVAKDLVKFDPKlRKALSYLLGGVLVVddLDNALELAKKLRPGYRIVTldGD 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1461 PARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPAspdlDPEAVRGALREFLQELRSAQRERDELRTQTSALNRQLA 1540
Cdd:TIGR02168  654 LVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEE----KIAELEKALAELRKELEELEEELEQLRKELEELSRQIS 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1541 EM-------EAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATE 1613
Cdd:TIGR02168  730 ALrkdlarlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1614 SELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQV 1693
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462515701 1694 ADSEVKAGTLQLTVERLNGALakveeseGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTA 1758
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKR-------SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE 947
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1505-1996 2.07e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.76  E-value: 2.07e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1505 EAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQ 1584
Cdd:COG1196    249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1585 EESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:COG1196    329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNS 1744
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1745 TRDKNLHLQKALTACEH-DRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQR--VEAEGQLQQLREVLRQ 1821
Cdd:COG1196    489 AAARLLLLLEAEADYEGfLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNivVEDDEVAAAAIEYLKA 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1822 RQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSA 1901
Cdd:COG1196    569 AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1902 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQ 1981
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                          490
                   ....*....|....*
gi 2462515701 1982 RVSTLKGQLQQELRR 1996
Cdd:COG1196    729 QLEAEREELLEELLE 743
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1654-1983 2.13e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.76  E-value: 2.13e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1654 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTE 1733
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1734 ALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQ 1813
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1814 QLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSH 1893
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1894 EDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQ------LEVDAQQQQLELQQEVERLRSAQAQ 1967
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330
                   ....*....|....*.
gi 2462515701 1968 TERTLEARERAHRQRV 1983
Cdd:COG1196    536 YEAALEAALAAALQNI 551
PTZ00121 PTZ00121
MAEBL; Provisional
 560-1252 9.81e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.04  E-value: 9.81e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  560 ESERRALEEQLQRLRDKTDGAMQAHE----------DAQREVQRLRSANELLSREKSNLAHslqvAQQQAEELRQEREKL 629
Cdd:PTZ00121  1143 EEARKAEDAKRVEIARKAEDARKAEEarkaedakkaEAARKAEEVRKAEELRKAEDARKAE----AARKAEEERKAEEAR 1218

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  630 QAAQEELRRQRDRLEEEQEDAVQdgARvRRELERSHRQLEQLEGKRSVLAKELVEVREAlSRATLQRDMLQAEKAEVAEA 709
Cdd:PTZ00121  1219 KAEDAKKAEAVKKAEEAKKDAEE--AK-KAEEERNNEEIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKADE 1294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  710 LTKAEAGRVELELsmtKLRAEEASLQDSLSKLSalneslAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQER 789
Cdd:PTZ00121  1295 AKKAEEKKKADEA---KKKAEEAKKADEAKKKA------EEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK 1365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  790 LEELRLEQEVARQGLEGSLRVAEQAQEALEQQlptlrhERSQLQEQLAQLSRQLSGREQELEQARREAQ--RQVEALERA 867
Cdd:PTZ00121  1366 AEAAEKKKEEAKKKADAAKKKAEEKKKADEAK------KKAEEDKKKADELKKAAAAKKKADEAKKKAEekKKADEAKKK 1439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  868 AREKEAlAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEG-SLFEVQRQLAQLEARREQLEAEGQALLLAKETLTG 946
Cdd:PTZ00121  1440 AEEAKK-ADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAkKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  947 ELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQAslrEQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEE 1026
Cdd:PTZ00121  1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA---EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIE 1595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1027 LLARLEAEKeelseeiaalQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRhslatislEMERQKRDAQSRQEQD 1106
Cdd:PTZ00121  1596 EVMKLYEEE----------KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKK--------EAEEKKKAEELKKAEE 1657

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1107 RSTVNAltselrdlrAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQlrlledarDGLRRELLEAQRKLRE 1186
Cdd:PTZ00121  1658 ENKIKA---------AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA--------EELKKKEAEEKKKAEE 1720

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462515701 1187 SQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRsavKKAESERISLKLANEDKEQKLALLEE 1252
Cdd:PTZ00121  1721 LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK---KIAHLKKEEEKKAEEIRKEKEAVIEE 1783
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 87-704 1.10e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.45  E-value: 1.10e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   87 QQELSRVEDLLAQSRAERDEL------AIKYNAVSERLEQALrlepgeletqeprglVRQSVELRRQLQEEQASYRRKLQ 160
Cdd:COG1196    185 EENLERLEDILGELERQLEPLerqaekAERYRELKEELKELE---------------AELLLLKLRELEAELEELEAELE 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  161 AYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLR 240
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  241 EQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAyfsnEHSRLLLLWRQVVGFRRLVSEVKMFTERD 320
Cdd:COG1196    330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE----AEEELEELAEELLEALRAAAELAAQLEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  321 LLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVT 400
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  401 ELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLqqTLRDLAQAVLSDSESGVQLSGSERTADAS 480
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA--AYEAALEAALAAALQNIVVEDDEVAAAAI 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  481 NGSLRGLSGQRTPSPPRRSSPGRGRSPRRgpspacsdssTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSE 560
Cdd:COG1196    564 EYLKAAKAGRATFLPLDKIRARAALAAAL----------ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  561 SERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQR 640
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462515701  641 DRLEEEQEDAVQdgARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 704
Cdd:COG1196    714 EERLEEELEEEA--LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1505-1974 1.47e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.06  E-value: 1.47e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1505 EAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQ 1584
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1585 EESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:COG1196    378 EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEES-----------EGALRDKVRGLTE 1733
Cdd:COG1196    458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAlllaglrglagAVAVLIGVEAAYE 537

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1734 ALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQ 1813
Cdd:COG1196    538 AALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1814 QLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSH 1893
Cdd:COG1196    618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1894 EDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLE 1973
Cdd:COG1196    698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777


                   .
gi 2462515701 1974 A 1974
Cdd:COG1196    778 A 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1511-1996 1.57e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.06  E-value: 1.57e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1511 LREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRR 1590
Cdd:COG1196    227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1591 SERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRL 1670
Cdd:COG1196    307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1671 GLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNL 1750
Cdd:COG1196    387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1751 HLQKALTACEHDRQVLQERLDAARQ---ALSEARKQSSSLGEQV-------------QTLRGEVADLELQRVEAEGQLQQ 1814
Cdd:COG1196    467 ELLEEAALLEAALAELLEELAEAAArllLLLEAEADYEGFLEGVkaalllaglrglaGAVAVLIGVEAAYEAALEAALAA 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1815 LREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHE 1894
Cdd:COG1196    547 ALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1895 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEA 1974
Cdd:COG1196    627 LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE 706

                          490       500
                   ....*....|....*....|..
gi 2462515701 1975 RERAHRQRVSTLKGQLQQELRR 1996
Cdd:COG1196    707 RELAEAEEERLEEELEEEALEE 728
PTZ00121 PTZ00121
MAEBL; Provisional
 597-1281 1.67e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 83.27  E-value: 1.67e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  597 ANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQ-----EELRRQRD--RLEEE---QEDAVQDGARVRRELERSHR 666
Cdd:PTZ00121  1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEdarkaEEARKAEDarKAEEArkaEDAKRVEIARKAEDARKAEE 1168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  667 QLEQLEGKRSVLAKELVEVREAlsratlqRDMLQAEKAEVAEALTKAEAGRvelelsmtklRAEEASLQDSLSKLSALNE 746
Cdd:PTZ00121  1169 ARKAEDAKKAEAARKAEEVRKA-------EELRKAEDARKAEAARKAEEER----------KAEEARKAEDAKKAEAVKK 1231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  747 SLAQDKldlnrlvaQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEgsLRVAEQAQEALEqqlptLR 826
Cdd:PTZ00121  1232 AEEAKK--------DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE--LKKAEEKKKADE-----AK 1296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  827 HERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREK----EALAKEHAGLAVQLVAAEREGRTLSEEATRL 902
Cdd:PTZ00121  1297 KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAkkaaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEA 1376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  903 RLEKEALEGSLFEVQRQLaqlEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKElMAQKLVQAErEAQA 982
Cdd:PTZ00121  1377 KKKADAAKKKAEEKKKAD---EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK-KAEEAKKAD-EAKK 1451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  983 SLREQRAAHE-----EDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAE 1057
Cdd:PTZ00121  1452 KAEEAKKAEEakkkaEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1058 sEKQQALSLKESEKTALSEKLMGTRHslatISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRR 1137
Cdd:PTZ00121  1532 -EAKKADEAKKAEEKKKADELKKAEE----LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKK 1606

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1138 LQ-EQAR-----------------------DLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREV 1193
Cdd:PTZ00121  1607 MKaEEAKkaeeakikaeelkkaeeekkkveQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEED 1686

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1194 QRQEAGELRRSLGEGAKEREALRRSNEELRSA--VKKAESER-ISLKLANEDKEQKLALLEEARTAVGkEAGELRTGLQE 1270
Cdd:PTZ00121  1687 EKKAAEALKKEAEEAKKAEELKKKEAEEKKKAeeLKKAEEENkIKAEEAKKEAEEDKKKAEEAKKDEE-EKKKIAHLKKE 1765

                          730
                   ....*....|.
gi 2462515701 1271 VERSRLEARRE 1281
Cdd:PTZ00121  1766 EEKKAEEIRKE 1776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 521-1255 3.52e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 82.04  E-value: 3.52e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  521 LALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESER--------RALEEQLQRLRDKTDGAMQAHEDAQREVQ 592
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEqlrvkekiGELEAEIASLERSIAEKERELEDAEERLA 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  593 RLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLE 672
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELK 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  673 GKRSVLAKELVEVREALsratlqrdmlqaekAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDK 752
Cdd:TIGR02169  406 RELDRLQEELQRLSEEL--------------ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  753 LDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSL----RVAEQAQEALEQQLPTLRHE 828
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVaqlgSVGERYATAIEVAAGNRLNN 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  829 RSQLQEQLAQLSRQLSGReqelEQARREAQRQVEALERAAREKEALAKEHA-GLAVQLVAAERE---------GRTLS-- 896
Cdd:TIGR02169  552 VVVEDDAVAKEAIELLKR----RKAGRATFLPLNKMRDERRDLSILSEDGViGFAVDLVEFDPKyepafkyvfGDTLVve 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  897 --EEATRL--RLEKEALEGSLFEVQ-------RQLAQLEARREQLEAEGQALLLAKETLTGELAGLRqqiiatQEKASLD 965
Cdd:TIGR02169  628 diEAARRLmgKYRMVTLEGELFEKSgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ------SELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  966 KELMAqkLVQAEREAQASLREQraahEEDLQRLQREKEAAWRELEAERAQLQSqLQREQEELLARLEAEKEELSEEIAAL 1045
Cdd:TIGR02169  702 NRLDE--LSQELSDASRKIGEI----EKEIEQLEQEEEKLKERLEELEEDLSS-LEQEIENVKSELKELEARIEELEEDL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1046 QQERDEgllLAESEKQQALSlKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQRE 1125
Cdd:TIGR02169  775 HKLEEA---LNDLEARLSHS-RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK 850

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1126 EaaaahaqevrrLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSL 1205
Cdd:TIGR02169  851 S-----------IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1206 GEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEART 1255
Cdd:TIGR02169  920 SELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRA 969
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
547-1027 2.30e-14

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 78.93  E-value: 2.30e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  547 DLLGTLRKQLSDSESERRALEEQ---LQRLRDKTDGAMQAHEDAQREVQRLRSANELLS-------REKSNLAHSLQVAQ 616
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELETLEAEIEDLRetiaeteREREELAEEVRDLR 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  617 QQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQR 696
Cdd:PRK02224   286 ERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  697 DMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQA 776
Cdd:PRK02224   366 AELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEA 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  777 EQeatvareeqerlEELRLEQEVARQGLEGSLRV-----AEQAQEALEQQLPTLRHERSQLQEQLAQLSrQLSGREQELE 851
Cdd:PRK02224   446 EA------------LLEAGKCPECGQPVEGSPHVetieeDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIE 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  852 QARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLE 931
Cdd:PRK02224   513 RLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  932 AEgQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKlvqAEREAQASLREQRAAHEEDLQRLQREKEA------A 1005
Cdd:PRK02224   593 RI-RTLLAAIADAEDEIERLREKREALAELNDERRERLAEK---RERKRELEAEFDEARIEEAREDKERAEEYleqveeK 668

                          490       500
                   ....*....|....*....|..
gi 2462515701 1006 WRELEAERAQLQSQLQREQEEL 1027
Cdd:PRK02224   669 LDELREERDDLQAEIGAVENEL 690
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 79-877 5.80e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 5.80e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   79 LQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRlepgeletqeprglvrqsveLRRQLQEEQASYRRK 158
Cdd:TIGR02168  286 LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES--------------------KLDELAEELAELEEK 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  159 LQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAM 238
Cdd:TIGR02168  346 LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEE 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  239 LREQLDQAGSANQALSEDIRKvtndwtRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVvgfRRLVSEVKMFte 318
Cdd:TIGR02168  426 LLKKLEEAELKELQAELEELE------EELEELQEELERLEEALEELREELEEAEQALDAAEREL---AQLQARLDSL-- 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  319 RDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKAdlSAR 398
Cdd:TIGR02168  495 ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNE--LGR 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  399 VTELGLAVKRlekqnlekdqVNKDLTEKLEALESLRLQEQAALETEdgeglqqTLRDLAQAVLSDSESGVQLSGSERTAD 478
Cdd:TIGR02168  573 VTFLPLDSIK----------GTEIQGNDREILKNIEGFLGVAKDLV-------KFDPKLRKALSYLLGGVLVVDDLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  479 ASNGSLRGLSGQRTPSpprrsspgrGRSPRRGPSPACSDSSTlalIHSALHKRQlQVQDMRGRYEASQDLLGTLRKQLSD 558
Cdd:TIGR02168  636 ELAKKLRPGYRIVTLD---------GDLVRPGGVITGGSAKT---NSSILERRR-EIEELEEKIEELEEKIAELEKALAE 702

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  559 SESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRR 638
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  639 QRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRV 718
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  719 ELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSAL-QGRQRQAEQEATVAREEQERLEELRLEQ 797
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELrRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  798 EVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS----------RQLSGREQELEQARREAQRQVEALERA 867
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGpvnlaaieeyEELKERYDFLTAQKEDLTEAKETLEEA 1022

                          810
                   ....*....|
gi 2462515701  868 AREKEALAKE 877
Cdd:TIGR02168 1023 IEEIDREARE 1032
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 984-1868 2.29e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.87  E-value: 2.29e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  984 LREQRAaHEEDLQRLQREKE--------AAWRELEAERAQLQSQLQREQEELlARLEAEKEELSEEIAALQQERDEglll 1055
Cdd:TIGR02169  203 LRRERE-KAERYQALLKEKReyegyellKEKEALERQKEAIERQLASLEEEL-EKLTEEISELEKRLEEIEQLLEE---- 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1056 aESEKQQALSLKESektalseklmgtrhslatisLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEV 1135
Cdd:TIGR02169  277 -LNKKIKDLGEEEQ--------------------LRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1136 RRLQEQARDLGKQRdsclREAEELRTQLRLLEDARDGLRRELLEAQRKLRESqegrevqRQEAGELRRSLGEGAKEREAL 1215
Cdd:TIGR02169  336 AEIEELEREIEEER----KRRDKLTEEYAELKEELEDLRAELEEVDKEFAET-------RDELKDYREKLEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1216 RRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSE 1295
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1296 NTRLGRELAELQGRLALGERAEKESRRETLGLRQRLlkgEASLEVMRQELQVaqrklqeqegefrtrERRLLGSLEEARG 1375
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASI---QGVHGTVAQLGSV---------------GERYATAIEVAAG 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1376 TEKQ------QLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAE-------LARVEVQRRAAEAQLGGLRSAL-- 1440
Cdd:TIGR02169  547 NRLNnvvvedDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEdgvigfaVDLVEFDPKYEPAFKYVFGDTLvv 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1441 ------RRGLGLGRAPSPAPRPVPGSPARDAPA-EGSGEGLNSPSTLECSPGSQPpspgpatspaspdlDPEAVRGALRE 1513
Cdd:TIGR02169  627 edieaaRRLMGKYRMVTLEGELFEKSGAMTGGSrAPRGGILFSRSEPAELQRLRE--------------RLEGLKRELSS 692

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1514 FLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSER 1593
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEE 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1594 ERRATLDQVATLERSLqateselraSQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLS 1673
Cdd:TIGR02169  773 DLHKLEEALNDLEARL---------SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1674 DREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQ 1753
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1754 KALtacehdrQVLQERLDaarqALSEARKQSSSLGEQVQTLRgevaDLELQRVEAEGQLQQLREVLRQRQEGEAAALNTV 1833
Cdd:TIGR02169  924 AKL-------EALEEELS----EIEDPKGEDEEIPEEELSLE----DVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRL 988

                          890       900       910
                   ....*....|....*....|....*....|....*
gi 2462515701 1834 QKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1868
Cdd:TIGR02169  989 DELKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 794-1565 3.11e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.48  E-value: 3.11e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  794 RLEQEVARQGLEGSLRVAEQAQEaLEQQLPTLRHERS-----QLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAA 868
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKE-LKAELRELELALLvlrleELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  869 REKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGEL 948
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  949 AGLRQQIIATQEK--ASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEaeraqlqsQLQREQEE 1026
Cdd:TIGR02168  354 ESLEAELEELEAEleELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE--------RLQQEIEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1027 LLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDaQSRQEQD 1106
Cdd:TIGR02168  426 LLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERL-QENLEGF 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1107 RSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDS-CLREAEELRTQLRLLEDARDGLRRELLEAQRKLR 1185
Cdd:TIGR02168  505 SEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAvVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1186 ESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKeaGELR 1265
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPG--GVIT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1266 TGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1345
Cdd:TIGR02168  663 GGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1346 QVAQRKLQEQEGE---FRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARV 1422
Cdd:TIGR02168  743 EQLEERIAQLSKElteLEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1423 EVQRRAAEAQLGGLRSALRRglglgrapspaprpvpgSPARDAPAEGSGEGLN-SPSTLECSPGSQPPSPGPAT-SPASP 1500
Cdd:TIGR02168  823 RERLESLERRIAATERRLED-----------------LEEQIEELSEDIESLAaEIEELEELIEELESELEALLnERASL 885

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462515701 1501 DLDPEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEE 1565
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950
PTZ00121 PTZ00121
MAEBL; Provisional
 558-1109 3.37e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.56  E-value: 3.37e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  558 DSESERRALEEQLQRLRDKTDGAMQAH---EDAQREVQRLRSANELLSREKSNLAHSLQVAQQ--QAEELRQEREKLQAA 632
Cdd:PTZ00121  1238 DAEEAKKAEEERNNEEIRKFEEARMAHfarRQAAIKAEEARKADELKKAEEKKKADEAKKAEEkkKADEAKKKAEEAKKA 1317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  633 Q------EELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR----EALSRATLQRDMLQAE 702
Cdd:PTZ00121  1318 DeakkkaEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKkkadAAKKKAEEKKKADEAK 1397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  703 K-----AEVAEALTKAEAGRVELElsMTKLRAEEASLQDSLSKlsalnesLAQDKLDLNRLVAQLEEEKSALQGRQRQAE 777
Cdd:PTZ00121  1398 KkaeedKKKADELKKAAAAKKKAD--EAKKKAEEKKKADEAKK-------KAEEAKKADEAKKKAEEAKKAEEAKKKAEE 1468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  778 QEATvarEEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQElEQARREA 857
Cdd:PTZ00121  1469 AKKA---DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAD-EAKKAEE 1544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  858 QRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQAL 937
Cdd:PTZ00121  1545 KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE 1624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  938 LLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ 1017
Cdd:PTZ00121  1625 LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA 1704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1018 SQLQREQEELLARLEAEKEELSEEIAALQQERDEglllAESEKQQALSLK--ESEKTALSEKLMGTRHSLATISLEMER- 1094
Cdd:PTZ00121  1705 EELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE----AEEDKKKAEEAKkdEEEKKKIAHLKKEEEKKAEEIRKEKEAv 1780

                          570       580
                   ....*....|....*....|
gi 2462515701 1095 -----QKRDAQSRQEQDRST 1109
Cdd:PTZ00121  1781 ieeelDEEDEKRRMEVDKKI 1800
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1000-1865 3.61e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.49  E-value: 3.61e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1000 REKEAAWRELEaeraqlqsqlqrEQEELLARLEAEKEELSEEIAALQQERDEglllaeSEKQQALS--LKESEKTALSEK 1077
Cdd:TIGR02169  170 RKKEKALEELE------------EVEENIERLDLIIDEKRQQLERLRREREK------AERYQALLkeKREYEGYELLKE 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1078 LMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEqardlgkqrdsclrEAE 1157
Cdd:TIGR02169  232 KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKE--------------KIG 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1158 ELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALrrsneelrsavkkaESERISLK 1237
Cdd:TIGR02169  298 ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKL--------------TEEYAELK 363

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1238 LANEDKEQKLAlleeartAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAE 1317
Cdd:TIGR02169  364 EELEDLRAELE-------EVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKI 436

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1318 KESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQldhargleLKLEAARAE 1397
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA--------RASEERVRG 508

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1398 AAELGLRLSAAEGRAQGLEAELARVEVQRRAA-EAQLGG-LRSALRRGLGLGRAPSPAPRPVPGSPARDAPaegsgegLN 1475
Cdd:TIGR02169  509 GRAVEEVLKASIQGVHGTVAQLGSVGERYATAiEVAAGNrLNNVVVEDDAVAKEAIELLKRRKAGRATFLP-------LN 581

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1476 SPSTLECSPGSQPPSPGPATSPASPDLDPE---AVRGALREFL--QELRSAQRERDELRTQTsaLNRQLAEMEAERDSAT 1550
Cdd:TIGR02169  582 KMRDERRDLSILSEDGVIGFAVDLVEFDPKyepAFKYVFGDTLvvEDIEAARRLMGKYRMVT--LEGELFEKSGAMTGGS 659

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1551 SRARQLQKAVAESEEARRSVDGRLSGVQAELAlqeesvrrsererrATLDQVATLERSLQATESELRASQEKISKMKANE 1630
Cdd:TIGR02169  660 RAPRGGILFSRSEPAELQRLRERLEGLKRELS--------------SLQSELRRIENRLDELSQELSDASRKIGEIEKEI 725

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1631 TKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKagtlqltverl 1710
Cdd:TIGR02169  726 EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIP----------- 794

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1711 ngalaKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQ 1790
Cdd:TIGR02169  795 -----EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE 869

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462515701 1791 VQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVE 1865
Cdd:TIGR02169  870 LEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
530-1012 1.95e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 73.03  E-value: 1.95e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  530 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAH--------EDAQREVQRLRSANELL 601
Cdd:COG4913    278 RAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIrgnggdrlEQLEREIERLERELEER 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  602 SREKSNLAHSLQVAQQQ----AEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSV 677
Cdd:COG4913    358 ERRRARLEALLAALGLPlpasAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  678 LAKELVEVREALSRAtlqrdmLQAEKAE---VAEALTKAEAGR-----VELELSMTKLR--AEEASLQDSLS-------- 739
Cdd:COG4913    438 IPARLLALRDALAEA------LGLDEAElpfVGELIEVRPEEErwrgaIERVLGGFALTllVPPEHYAAALRwvnrlhlr 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  740 ------KLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGL--EGSLRVA 811
Cdd:COG4913    512 grlvyeRVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRFDYVCVDSPEELRRHPRAITRAGQvkGNGTRHE 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  812 EQAQEAL----------EQQLPTLRHERSQLQEQLAQLSRQLSGREQELE--QARREAQRQVEALERAAREKEALAKEHA 879
Cdd:COG4913    592 KDDRRRIrsryvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDalQERREALQRLAEYSWDEIDVASAEREIA 671

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  880 GLAVQLVAAER---EGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLtGELAGLRQQII 956
Cdd:COG4913    672 ELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA-EDLARLELRAL 750

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462515701  957 ATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAE 1012
Cdd:COG4913    751 LEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETAD 806
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1578-2001 1.38e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.97  E-value: 1.38e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1578 QAELALQEESVRRSERErratldqvatleRSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQ 1657
Cdd:COG1196    208 QAEKAERYRELKEELKE------------LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1658 RRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQ 1737
Cdd:COG1196    276 LEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1738 SSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLRE 1817
Cdd:COG1196    356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1818 VLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAekrevERSALRLEKDRVALRRTLDKVEREKLRSHEDTV 1897
Cdd:COG1196    436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA-----ALAELLEELAEAAARLLLLLEAEADYEGFLEGV 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1898 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARER 1977
Cdd:COG1196    511 KAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAA 590

                          410       420
                   ....*....|....*....|....
gi 2462515701 1978 AHRQRVSTLKGQLQQELRRSSAPF 2001
Cdd:COG1196    591 ALARGAIGAAVDLVASDLREADAR 614
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1521-1983 2.82e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 69.17  E-value: 2.82e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1521 AQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDG-RLSGVQAELALQEESVRRSERERRATL 1599
Cdd:COG4913    286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGdRLEQLEREIERLERELEERERRRARLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1600 DQVATLERSLQATESELRASQEKIskmKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSD----- 1674
Cdd:COG4913    366 ALLAALGLPLPASAEEFAALRAEA---AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNiparl 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1675 ---REAQAQALQDRVDSLQ-----RQVADSEVK------------AGTLQLTVERLNGALAKVEESEGALR---DKVRGL 1731
Cdd:COG4913    443 lalRDALAEALGLDEAELPfvgelIEVRPEEERwrgaiervlggfALTLLVPPEHYAAALRWVNRLHLRGRlvyERVRTG 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1732 TEALAQSSASLNSTRDKnlhlqkaLTACEHD-----RQVLQERLDAA-----------RQALSEA--RKQSSSLGE---- 1789
Cdd:COG4913    523 LPDPERPRLDPDSLAGK-------LDFKPHPfrawlEAELGRRFDYVcvdspeelrrhPRAITRAgqVKGNGTRHEkddr 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1790 ---------------QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEgEAAALNTVQKLQDErrllQERLGSLQRAL 1854
Cdd:COG4913    596 rrirsryvlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQE-RREALQRLAEYSWD----EIDVASAEREI 670

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1855 AQLEAEKREVERSALRLEkdrvALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVl 1934
Cdd:COG4913    671 AELEAELERLDASSDDLA----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL- 745

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 2462515701 1935 eqshsPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRV 1983
Cdd:COG4913    746 -----ELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 76-672 5.20e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 5.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   76 LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQAlrlepgeletqeprglvrqsVELRRQLQEEQASY 155
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL--------------------ELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQV 235
Cdd:COG1196    294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  236 NAMLREQLDQAGSANQALSEDIRKVTNDwtrcRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKM 315
Cdd:COG1196    374 LAEAEEELEELAEELLEALRAAAELAAQ----LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  316 FTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADL 395
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  396 SARVTELGLAV-----KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQL 470
Cdd:COG1196    530 IGVEAAYEAALeaalaAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  471 SGSERTADASNGSLrglsgqrtpspprrsspgrgrsprrgpspacSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLG 550
Cdd:COG1196    610 EADARYYVLGDTLL-------------------------------GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  551 TLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQ 630
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2462515701  631 AAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLE 672
Cdd:COG1196    739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 564-931 1.29e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 1.29e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  564 RALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRL 643
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  644 EEEQEDAVQDGARVRRELERSHRQLEQLEgkrsvlakelvevreaLSRATLQRDMLQAEKAEVAEALTKAEAGRVELELS 723
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLE----------------EALNDLEARLSHSRIPEIQAELSKLEEEVSRIEAR 813

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  724 MTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQG 803
Cdd:TIGR02169  814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  804 LEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSgreqELEQARREAQRQVEALERAAREKEalakehaglav 883
Cdd:TIGR02169  894 LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS----EIEDPKGEDEEIPEEELSLEDVQA----------- 958

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 2462515701  884 QLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLE 931
Cdd:TIGR02169  959 ELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
534-1027 1.40e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 66.86  E-value: 1.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  534 QVQDMRGRYEASQDLLGTLRKQLsdsESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQ 613
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQI---ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  614 VAQQQAEELRQEREKLQAAQEELRRQR--------DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEV 685
Cdd:COG4913    306 RLEAELERLEARLDALREELDELEAQIrgnggdrlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  686 REALSRAtlqRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQ--------DSLSKLSALNESLAQDKLDLnR 757
Cdd:COG4913    386 RAEAAAL---LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLErrksnipaRLLALRDALAEALGLDEAEL-P 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  758 LVAQL----EEEKS-------ALQGRQR----QAEQEATVAR-------------EEQERLEELRLEQEVARQGLEGSLR 809
Cdd:COG4913    462 FVGELievrPEEERwrgaierVLGGFALtllvPPEHYAAALRwvnrlhlrgrlvyERVRTGLPDPERPRLDPDSLAGKLD 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  810 VAE-QAQEALEQQL------------PTLRHERSQL-------------------------------QEQLAQLSRQLsg 845
Cdd:COG4913    542 FKPhPFRAWLEAELgrrfdyvcvdspEELRRHPRAItragqvkgngtrhekddrrrirsryvlgfdnRAKLAALEAEL-- 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  846 reQELEQARREAQRQVEALERAAREKEALAKEHAGLAvQLVAAEREGRTLSEEATRLRLEKEALEGSlfevQRQLAQLEA 925
Cdd:COG4913    620 --AELEEELAEAEERLEALEAELDALQERREALQRLA-EYSWDEIDVASAEREIAELEAELERLDAS----SDDLAALEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  926 RREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRlqrekEAA 1005
Cdd:COG4913    693 QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVE-----REL 767

                          570       580
                   ....*....|....*....|..
gi 2462515701 1006 WRELEAERAQLQSQLQREQEEL 1027
Cdd:COG4913    768 RENLEERIDALRARLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
831-1367 3.03e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 65.71  E-value: 3.03e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  831 QLQEQLAQLSRqlsgreqeLEQARREAQRQVEALERAAREKEALAKEHAGLAVQlvAAEREGRTLSEEATRLRLEKEALE 910
Cdd:COG4913    229 ALVEHFDDLER--------AHEALEDAREQIELLEPIRELAERYAAARERLAEL--EYLRAALRLWFAQRRLELLEAELE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  911 gslfEVQRQLAQLEARREQLEAEgqalllaKETLTGELAGLRQQI--IATQEKASLDKELMAQKLVQAEREAQ------- 981
Cdd:COG4913    299 ----ELRAELARLEAELERLEAR-------LDALREELDELEAQIrgNGGDRLEQLEREIERLERELEERERRrarleal 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  982 -ASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQsQLQREQEELLARLEAEKEELSEEIAALQQER---DEGLLLAE 1057
Cdd:COG4913    368 lAALGLPLPASAEEFAALRAEAAALLEALEEELEALE-EALAEAEAALRDLRRELRELEAEIASLERRKsniPARLLALR 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1058 SEKQQALSLKESEKTALSEkLM--------------GTRHSLATISLEMERQKRDAQS--RQEQDRSTVNalTSELRDLR 1121
Cdd:COG4913    447 DALAEALGLDEAELPFVGE-LIevrpeeerwrgaieRVLGGFALTLLVPPEHYAAALRwvNRLHLRGRLV--YERVRTGL 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1122 AQREEAAAAHAQEVRRLQEQA--------RDLGKQRD-SCLREAEELRTQLRLL--------------EDARDGLRRELL 1178
Cdd:COG4913    524 PDPERPRLDPDSLAGKLDFKPhpfrawleAELGRRFDyVCVDSPEELRRHPRAItragqvkgngtrheKDDRRRIRSRYV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1179 ---EAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANE--DKEQKLALLEEA 1253
Cdd:COG4913    604 lgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREiaELEAELERLDAS 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1254 RTAVgkeaGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLK 1333
Cdd:COG4913    684 SDDL----AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL 759

                          570       580       590
                   ....*....|....*....|....*....|....
gi 2462515701 1334 GEASLEVMRQELQVAQRKLQEQEGEFRTRERRLL 1367
Cdd:COG4913    760 GDAVERELRENLEERIDALRARLNRAEEELERAM 793
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1602-1937 3.47e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.47  E-value: 3.47e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1602 VATLERSLQATESELRASQEKISKmkaNETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQA 1681
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIER---LDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1682 LQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKV--------EESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQ 1753
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkikdlgEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1754 KALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTV 1833
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1834 QKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGA 1913
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340
                   ....*....|....*....|....
gi 2462515701 1914 ELELAEAQRQIQQLEAQVVVLEQS 1937
Cdd:TIGR02169  482 EKELSKLQRELAEAEAQARASEER 505
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1555-1867 3.47e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 3.47e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1555 QLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELrasQEKISKMKANETKLE 1634
Cdd:TIGR02169  199 QLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEI---SELEKRLEEIEQLLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1635 GDKRRLKEvLDASESRTVK-----LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVER 1709
Cdd:TIGR02169  276 ELNKKIKD-LGEEEQLRVKekigeLEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDK 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1710 LNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGE 1789
Cdd:TIGR02169  355 LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA 434

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462515701 1790 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEgeaaalnTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERS 1867
Cdd:TIGR02169  435 KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ-------ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
PTZ00121 PTZ00121
MAEBL; Provisional
 560-1189 3.72e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 3.72e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  560 ESERRALEEQLQRLRDKTDGAMQAheDAQREVQRLRSANELLSREKSNLAHSLQvaqqQAEELRQEREKLQAAQEELRRQ 639
Cdd:PTZ00121  1179 EAARKAEEVRKAEELRKAEDARKA--EAARKAEEERKAEEARKAEDAKKAEAVK----KAEEAKKDAEEAKKAEEERNNE 1252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  640 RDRLEEEQEDA--VQDGARVRRELERSHRQLEQLEGKRSvlAKELVEVREALSRATLQRDMLQAEKAEVA-----EALTK 712
Cdd:PTZ00121  1253 EIRKFEEARMAhfARRQAAIKAEEARKADELKKAEEKKK--ADEAKKAEEKKKADEAKKKAEEAKKADEAkkkaeEAKKK 1330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  713 AEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLdlnrlvaQLEEEKSALQGRQRQAEQ-----EATVAREEQ 787
Cdd:PTZ00121  1331 ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK-------KKEEAKKKADAAKKKAEEkkkadEAKKKAEED 1403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  788 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALE-R 866
Cdd:PTZ00121  1404 KKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEaK 1483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  867 AAREKEALAKEHAGLAVQLVAAErEGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEgqalllaketltg 946
Cdd:PTZ00121  1484 KADEAKKKAEEAKKKADEAKKAA-EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD------------- 1549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  947 ELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWREL-EAERAQLQSQLQREQE 1025
Cdd:PTZ00121  1550 ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAkKAEEAKIKAEELKKAE 1629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1026 EL---LARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSR 1102
Cdd:PTZ00121  1630 EEkkkVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1103 QEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQAR-DLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQ 1181
Cdd:PTZ00121  1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKkDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEED 1789


                   ....*...
gi 2462515701 1182 RKLRESQE 1189
Cdd:PTZ00121  1790 EKRRMEVD 1797
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
680-1311 4.75e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.85  E-value: 4.75e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  680 KELVEVREALSRATLQRDMLQAEKaEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLsklsalnesLAQDKLDLNRLV 759
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEPIR-ELAERYAAARERLAELEYLRAALRLWFAQRRLEL---------LEAELEELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  760 AQLEEEKSALQGRQRQAEQEATVAREeqerleelrleqevARQGLEGS-LRVAEQAQEALEQQLPTLRHERSQLQEQLAQ 838
Cdd:COG4913    305 ARLEAELERLEARLDALREELDELEA--------------QIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  839 LSRQLSGREQELEQARREAQrqvEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQR 918
Cdd:COG4913    371 LGLPLPASAEEFAALRAEAA---ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRD 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  919 QLAQ---------------LEARREQLEAE--------GQALLLA--------------KETLTGELAGLR-QQIIATQE 960
Cdd:COG4913    448 ALAEalgldeaelpfvgelIEVRPEEERWRgaiervlgGFALTLLvppehyaaalrwvnRLHLRGRLVYERvRTGLPDPE 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  961 KASLDKELMAQKLVQAEREAQASLRE---QRAAHE--EDLQRLQREKEAAWRE----LEAERAQLQSQLQREQEELLARl 1031
Cdd:COG4913    528 RPRLDPDSLAGKLDFKPHPFRAWLEAelgRRFDYVcvDSPEELRRHPRAITRAgqvkGNGTRHEKDDRRRIRSRYVLGF- 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1032 eaekeELSEEIAALQQERDEglllAESEKQQALSLKESEKTALseKLMGTRHSLATISLEMERQKRDAQSRQEQdrstVN 1111
Cdd:COG4913    607 -----DNRAKLAALEAELAE----LEEELAEAEERLEALEAEL--DALQERREALQRLAEYSWDEIDVASAERE----IA 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1112 ALTSELRDLraqreeaaAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE-SQEG 1190
Cdd:COG4913    672 ELEAELERL--------DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLA 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1191 REVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISL-KLANEDKEQKLALLEEARTAVGkEAGELRTGLQ 1269
Cdd:COG4913    744 RLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELeRAMRAFNREWPAETADLDADLE-SLPEYLALLD 822

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|..
gi 2462515701 1270 EVERSRLEARRElqelrrqmKMLDSENTRLGRELAELQGRLA 1311
Cdd:COG4913    823 RLEEDGLPEYEE--------RFKELLNENSIEFVADLLSKLR 856
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 543-1010 4.83e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 61.78  E-value: 4.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  543 EASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSL-QVAQQQAEE 621
Cdd:pfam12128  467 ENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLlHFLRKEAPD 546

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  622 LRQEREKLQAAQEELRRQRD-RLEEEQEDAVQDGARVRRELER-----SHRQLEQLEGKRSVLAKELVEVREALSRATLQ 695
Cdd:pfam12128  547 WEQSIGKVISPELLHRTDLDpEVWDGSVGGELNLYGVKLDLKRidvpeWAASEEELRERLDKAEEALQSAREKQAAAEEQ 626

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  696 RDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDslsklsALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQ 775
Cdd:pfam12128  627 LVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKD------KKNKALAERKDSANERLNSLEAQLKQLDKKHQA 700

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  776 AEQEatvareEQERLEELRLEQEVARQGLEGSLRVAE-QAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQAR 854
Cdd:pfam12128  701 WLEE------QKEQKREARTEKQAYWQVVEGALDAQLaLLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLK 774

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  855 REAQRQVEALERAAREKEALAKEHAGLAvqlvaaeregRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEA----RREQL 930
Cdd:pfam12128  775 REIRTLERKIERIAVRRQEVLRYFDWYQ----------ETWLQRRPRLATQLSNIERAISELQQQLARLIAdtklRRAKL 844

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  931 EAEGQALLLAKETLTGELAGLRQQIiatqekasldKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELE 1010
Cdd:pfam12128  845 EMERKASEKQQVRLSENLRGLRCEM----------SKLATLKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVE 914
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 592-1358 6.64e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 61.29  E-value: 6.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  592 QRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREklqaAQEELRRQRDRLEEEQEDAVQ------DGARVRRE--LER 663
Cdd:pfam15921   92 RRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERD----AMADIRRRESQSQEDLRNQLQntvhelEAAKCLKEdmLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  664 SHRQLEQL-------EGKRSVLAKELVEVREALSRATLQRDMLQAEK-AEVAEALTKAEAgrvELELSMTKLRAEEASLQ 735
Cdd:pfam15921  168 SNTQIEQLrkmmlshEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHfRSLGSAISKILR---ELDTEISYLKGRIFPVE 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  736 DSLSKLSALNES-----LAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVA---------- 800
Cdd:pfam15921  245 DQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMymrqlsdles 324

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  801 -----RQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALA 875
Cdd:pfam15921  325 tvsqlRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLW 404

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  876 KEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSL-FEVQRQLAQLEARREQLEaegqalllAKETLTGELAGLRQQ 954
Cdd:pfam15921  405 DRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQGKNESLE--------KVSSLTAQLESTKEM 476

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  955 IIATQEkasldkELMAQKLVQAEREAQASlreqraaheeDLQRLQREKEAAWRELEAERAQLQSQLQREQEEllarleae 1034
Cdd:pfam15921  477 LRKVVE------ELTAKKMTLESSERTVS----------DLTASLQEKERAIEATNAEITKLRSRVDLKLQE-------- 532

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1035 keelseeiaaLQQERDEGLLLAESEKQ-QALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNAL 1113
Cdd:pfam15921  533 ----------LQHLKNEGDHLRNVQTEcEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDR 602

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1114 TSELRDLraqrEEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREV 1193
Cdd:pfam15921  603 RLELQEF----KILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEV 678

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1194 qrqeageLRRSLGEGAKERE-ALRRSNEELRSAVKKAESERISLKL--ANEDKEQKLAL-LEEARTAVGKEAGELRTGLQ 1269
Cdd:pfam15921  679 -------LKRNFRNKSEEMEtTTNKLKMQLKSAQSELEQTRNTLKSmeGSDGHAMKVAMgMQKQITAKRGQIDALQSKIQ 751

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1270 EVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLalgERAEKESRRetlgLRQRLLKGEASLEVMRQELQVAQ 1349
Cdd:pfam15921  752 FLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGEL---EVLRSQERR----LKEKVANMEVALDKASLQFAECQ 824


                   ....*....
gi 2462515701 1350 RKLQEQEGE 1358
Cdd:pfam15921  825 DIIQRQEQE 833
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 550-1374 6.95e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.14  E-value: 6.95e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  550 GTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQ-------VAQQQAEEL 622
Cdd:pfam02463  142 GKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQakkaleyYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  623 RQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAE 702
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  703 KAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATV 782
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  783 AREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVE 862
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  863 ALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKE 942
Cdd:pfam02463  462 KDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  943 TLTGELAGLRQQIIATQEKASLDKE--------LMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERA 1014
Cdd:pfam02463  542 KVAISTAVIVEVSATADEVEERQKLvraltelpLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1015 QLQSQLQREQEELLARLEAEKEELSEEIAALQQERdeglLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 1094
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEE----GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRR 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1095 QKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLR 1174
Cdd:pfam02463  698 QLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1175 RELLEAQRKLRESQEGREVQRQEagELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEAR 1254
Cdd:pfam02463  778 EEREKTEKLKVEEEKEEKLKAQE--EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1255 TAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETlgLRQRLLKG 1334
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE--EAEILLKY 933

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 2462515701 1335 EASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEAR 1374
Cdd:pfam02463  934 EEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1505-1995 2.20e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 2.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1505 EAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARrsvdgrlSGVQAELALq 1584
Cdd:PRK02224   233 RETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER-------DDLLAEAGL- 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1585 eesvrrSERERRATLDQVATLERSLQATESELRASQEKIskmkaneTKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:PRK02224   305 ------DDADAEAVEARREELEDRDEELRDRLEECRVAA-------QAHNEEAESLREDADDLEERAEELREEAAELESE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSA---- 1740
Cdd:PRK02224   372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAllea 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1741 -----------------SLNSTRDKNLHLQKALTACEHDRQVLQERLDAArQALSEARKQSSSLGEQVQTLRGEVADLEL 1803
Cdd:PRK02224   452 gkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1804 QRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEK---------- 1873
Cdd:PRK02224   531 TIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAiadaedeier 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1874 --DRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRtLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAqqqQ 1951
Cdd:PRK02224   611 lrEKREALAELNDERRERLAEKRERKRELEAEFDEAR-IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGA---V 686

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 2462515701 1952 LELQQEVERLRSAQAQTERTLEARERAHRQ--RVSTLKGQLQQELR 1995
Cdd:PRK02224   687 ENELEELEELRERREALENRVEALEALYDEaeELESMYGDLRAELR 732
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
534-1031 4.08e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.51  E-value: 4.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  534 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQ 613
Cdd:PRK02224   238 EADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARRE 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  614 VAQQQAEELRQEREKLQAAQEELRRQRDRLEE-------EQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 686
Cdd:PRK02224   318 ELEDRDEELRDRLEECRVAAQAHNEEAESLREdaddleeRAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELR 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  687 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELElsmTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEk 766
Cdd:PRK02224   398 ERFGDAPVDLGNAEDFLEELREERDELREREAELE---ATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEED- 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  767 salqgRQRQAEQEATVAREEQERLEELRL-EQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSG 845
Cdd:PRK02224   474 -----RERVEELEAELEDLEEEVEEVEERlERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAE 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  846 REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS------EEATRLRLEKEALEGSLFEVQRQ 919
Cdd:PRK02224   549 LEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAaiadaeDEIERLREKREALAELNDERRER 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  920 LAQLEARREQLEAE--GQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQ-KLVQAEREAQASLREQRAAHEEDLQ 996
Cdd:PRK02224   629 LAEKRERKRELEAEfdEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEiGAVENELEELEELRERREALENRVE 708

                          490       500       510
                   ....*....|....*....|....*....|....*
gi 2462515701  997 RLQREKEAAwRELEAERAQLQSQLQREQEELLARL 1031
Cdd:PRK02224   709 ALEALYDEA-EELESMYGDLRAELRQRNVETLERM 742
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 608-859 6.25e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.08  E-value: 6.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  608 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVRE 687
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  688 ALSRATLQRDMLQAEKAEVAEALTKAEagrvelELSMTKLRAEEASLQDSLSKLSALNESLAQDKldlnRLVAQLEEEKS 767
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLG------RQPPLALLLSPEDFLDAVRRLQYLKYLAPARR----EQAEELRADLA 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  768 ALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 847
Cdd:COG4942    161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240

                          250
                   ....*....|..
gi 2462515701  848 QELEQARREAQR 859
Cdd:COG4942    241 ERTPAAGFAALK 252
mukB PRK04863
chromosome partition protein MukB;
561-1256 6.98e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 58.04  E-value: 6.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  561 SERRALEEQLQRLRdktdgamQAHEDAQREVQRLRSANELLSReksnlahslqvAQQQAEELRQEREKLQAAQEELRRQR 640
Cdd:PRK04863   506 REQRHLAEQLQQLR-------MRLSELEQRLRQQQRAERLLAE-----------FCKRLGKNLDDEDELEQLQEELEARL 567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  641 DRLEEEQEDAVQDGARVRRELErshrQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVEL 720
Cdd:PRK04863   568 ESLSESVSEARERRMALRQQLE----QLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLEREREL 643

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  721 ELSMTKLRAEEASLQDSLSKLSALN----ESLAQDKLDLN-RLVAQLEE--------EKSALQGRQRQA----------E 777
Cdd:PRK04863   644 TVERDELAARKQALDEEIERLSQPGgsedPRLNALAERFGgVLLSEIYDdvsledapYFSALYGPARHAivvpdlsdaaE 723

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  778 Q--------------EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEAL------EQQLPTLRHERSQLQEQLA 837
Cdd:PRK04863   724 QlagledcpedlyliEGDPDSFDDSVFSVEELEKAVVVKIADRQWRYSRFPEVPLfgraarEKRIEQLRAEREELAERYA 803

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  838 QLSRQlsgreqeleqaRREAQRQVEALERaarekeaLAKEHAGLAVQlVAAEREGRTLSEEATRLRLEKEALEGSLFEVQ 917
Cdd:PRK04863   804 TLSFD-----------VQKLQRLHQAFSR-------FIGSHLAVAFE-ADPEAELRQLNRRRVELERALADHESQEQQQR 864

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  918 RQLAQLEARREQLEA-EGQALLLAKETLTGELAGLRQQIIATQE-KASLDKElmAQKLVQAEREAqASLREQraahEEDL 995
Cdd:PRK04863   865 SQLEQAKEGLSALNRlLPRLNLLADETLADRVEEIREQLDEAEEaKRFVQQH--GNALAQLEPIV-SVLQSD----PEQF 937

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  996 QRLQREKEAAwrelEAERAQLQSQLqREQEELLARLeaekeelseeiAALQQERDEGLLLAESEKQQALSLK----ESEK 1071
Cdd:PRK04863   938 EQLKQDYQQA----QQTQRDAKQQA-FALTEVVQRR-----------AHFSYEDAAEMLAKNSDLNEKLRQRleqaEQER 1001

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1072 TALSEKLMGTRHSLAtislEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAhaqevrRLQEQARDLGKQRDS 1151
Cdd:PRK04863  1002 TRAREQLRQAQAQLA----QYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEE------RARARRDELHARLSA 1071

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1152 CLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRR-----SNEELRSAV 1226
Cdd:PRK04863  1072 NRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNGVERRLHRRelaylSADELRSMS 1151

                          730       740       750
                   ....*....|....*....|....*....|...
gi 2462515701 1227 KKAESeriSLKLA---NEDKEQKLALLEEARTA 1256
Cdd:PRK04863  1152 DKALG---ALRLAvadNEHLRDVLRLSEDPKRP 1181
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 566-1239 2.89e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.89  E-value: 2.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  566 LEEQLQRLR----DKTDGAMQAHEDaqrEVQRLRSANELlsrEKSNLAHSLQVAQQQAEELRQErekLQAAQEELRRQRD 641
Cdd:pfam15921  243 VEDQLEALKsesqNKIELLLQQHQD---RIEQLISEHEV---EITGLTEKASSARSQANSIQSQ---LEIIQEQARNQNS 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  642 RLEEEQEDAVQDGARVRRELERSHRQLEQlegKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTK--AEAGRVE 719
Cdd:pfam15921  314 MYMRQLSDLESTVSQLRSELREAKRMYED---KIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKllADLHKRE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  720 LELSMTKLRAEEASLQDSLSKLSA--LNESLAQDKLDLNRLVAQLEEEKSALQGRQRQaeqeatvareeqerleelrleQ 797
Cdd:pfam15921  391 KELSLEKEQNKRLWDRDTGNSITIdhLRRELDDRNMEVQRLEALLKAMKSECQGQMER---------------------Q 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  798 EVARQGLEGSLrvaeqaqealeQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKE 877
Cdd:pfam15921  450 MAAIQGKNESL-----------EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAE 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  878 HAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQalLLAKEtltGELAGLRQQiia 957
Cdd:pfam15921  519 ITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQ--LVGQH---GRTAGAMQV--- 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  958 tqEKASLDKELMAQKLvqaereaqaslreqraaHEEDLQRLQREKEAAWRELEAERAQLQSQLQReqeellarleaekee 1037
Cdd:pfam15921  591 --EKAQLEKEINDRRL-----------------ELQEFKILKDKKDAKIRELEARVSDLELEKVK--------------- 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1038 lseeiaalqqerdegLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSEL 1117
Cdd:pfam15921  637 ---------------LVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQL 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1118 RdlraqreeaaaAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQE 1197
Cdd:pfam15921  702 K-----------SAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEE 770

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|..
gi 2462515701 1198 AGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLA 1239
Cdd:pfam15921  771 KNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVA 812
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 552-1365 5.70e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.98  E-value: 5.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  552 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQA 631
Cdd:pfam02463  197 LQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  632 AQEELRRQRDRLEEEQEDAvqdgARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALT 711
Cdd:pfam02463  277 EEKEKKLQEEELKLLAKEE----EELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKRE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  712 KAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLE 791
Cdd:pfam02463  353 AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEIL 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  792 ELRLEQEVARQGLEGSLRVAEQAQEALEQ-------QLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 864
Cdd:pfam02463  433 EEEEESIELKQGKLTEEKEELEKQELKLLkdelelkKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  865 ERAAREKEAL-------AKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEvqRQLAQLEARREQLEAEGQAL 937
Cdd:pfam02463  513 LALIKDGVGGriisahgRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL--TELPLGARKLRLLIPKLKLP 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  938 LLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ 1017
Cdd:pfam02463  591 LKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSE 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1018 SQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKL-MGTRHSLATISLEMERQK 1096
Cdd:pfam02463  671 LTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQdKINEELKLLKQKIDEEEE 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1097 RDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRE 1176
Cdd:pfam02463  751 EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKI 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1177 LLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTA 1256
Cdd:pfam02463  831 KEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLN 910

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1257 VGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEA 1336
Cdd:pfam02463  911 LLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERY 990

                          810       820
                   ....*....|....*....|....*....
gi 2462515701 1337 SLEVMRQELQVAQRKLQEQEGEFRTRERR 1365
Cdd:pfam02463  991 NKDELEKERLEEEKKKLIRAIIEETCQRL 1019
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 554-772 6.70e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.00  E-value: 6.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  554 KQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAaq 633
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA-- 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  634 eELRRQRDRLEEEQEDAVQDGARVRREL-------ERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEV 706
Cdd:COG4942     98 -ELEAQKEELAELLRALYRLGRQPPLALllspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462515701  707 AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGR 772
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 535-1202 6.97e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 54.96  E-value: 6.97e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  535 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDG--AMQAHEDAQREVQRLRSANELLSR--------- 603
Cdd:COG3096    443 LAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEveRSQAWQTARELLRRYRSQQALAQRlqqlraqla 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  604 EKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELV 683
Cdd:COG3096    523 ELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAP 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  684 EVREALSRATLQRDMLQAE---KAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDL-NRLV 759
Cdd:COG3096    603 AWLAAQDALERLREQSGEAladSQEVTAAMQQLLEREREATVERDELAARKQALESQIERLSQPGGAEDPRLLALaERLG 682

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  760 AQLEEEK------------SALQGRQRQA---EQEATVAREEQERLEELRLEQEVAR--QGLEGSLRVAEQAQEAL---- 818
Cdd:COG3096    683 GVLLSEIyddvtledapyfSALYGPARHAivvPDLSAVKEQLAGLEDCPEDLYLIEGdpDSFDDSVFDAEELEDAVvvkl 762

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  819 ---------------------EQQLPTLRHERSQLQEQLAQLSRqlsgreqeleqARREAQRQVEALERAAREKEALAKE 877
Cdd:COG3096    763 sdrqwrysrfpevplfgraarEKRLEELRAERDELAEQYAKASF-----------DVQKLQRLHQAFSQFVGGHLAVAFA 831

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  878 haglavqlVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEA-EGQALLLAKETLTGELAGLRQQII 956
Cdd:COG3096    832 --------PDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKlLPQANLLADETLADRLEELREELD 903

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  957 ATQEkasldkelmAQKLVQAEREAQASLREQRAAHEEDLQRLQrEKEAAWRELEAERAQLQSQLQrEQEELLARLEAEKE 1036
Cdd:COG3096    904 AAQE---------AQAFIQQHGKALAQLEPLVAVLQSDPEQFE-QLQADYLQAKEQQRRLKQQIF-ALSEVVQRRPHFSY 972

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1037 ELSEEIAALQQERDEGLllaesekQQALSLKESEKTALSEKLMGTRHSLATISLEMErqkrDAQSRQEQDRSTVNALTSE 1116
Cdd:COG3096    973 EDAVGLLGENSDLNEKL-------RARLEQAEEARREAREQLRQAQAQYSQYNQVLA----SLKSSRDAKQQTLQELEQE 1041

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1117 LRDLR-AQREEAAAAHAQEVRRLQEQAR-------DLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA-------Q 1181
Cdd:COG3096   1042 LEELGvQADAEAEERARIRRDELHEELSqnrsrrsQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAkagwcavL 1121

                          730       740
                   ....*....|....*....|....*.
gi 2462515701 1182 RKLRESQEGREVQR-----QEAGELR 1202
Cdd:COG3096   1122 RLARDNDVERRLHRrelayLSADELR 1147
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 825-1565 7.08e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.69  E-value: 7.08e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  825 LRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAvqlvaaEREGRTLSEEATRLRL 904
Cdd:TIGR02169  228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG------EEEQLRVKEKIGELEA 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  905 EKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQ--A 982
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKefA 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  983 SLREQRAAHEEDLQRLQREKEaawrELEAERAQLQSQLQREQEELlARLEAEKEELSEEIAALQQERDEglllaeseKQQ 1062
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREIN----ELKRELDRLQEELQRLSEEL-ADLNAAIAGIEAKINELEEEKED--------KAL 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1063 ALSLKESEKTALSEKLMGTRHSLATISLEMER-QKRDAQSRQEQDRstVNALTSELRDLRAQREEAAAAHAQEVRRLQEQ 1141
Cdd:TIGR02169  449 EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRvEKELSKLQRELAE--AEAQARASEERVRGGRAVEEVLKASIQGVHGT 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1142 ARDLGK---QRDSCLREAEELRTQLRLLEDARDGLRR-ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREA-LR 1216
Cdd:TIGR02169  527 VAQLGSvgeRYATAIEVAAGNRLNNVVVEDDAVAKEAiELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVdLV 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1217 RSNEELRSAVKKAeserISLKLANEDKEQKLALLEEARTAV--------------GKEAGELRTGLQEVERSRLEA-RRE 1281
Cdd:TIGR02169  607 EFDPKYEPAFKYV----FGDTLVVEDIEAARRLMGKYRMVTlegelfeksgamtgGSRAPRGGILFSRSEPAELQRlRER 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1282 LQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRT 1361
Cdd:TIGR02169  683 LEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1362 RERRLlGSLEEARGTEKQQLD--HARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSA 1439
Cdd:TIGR02169  763 LEARI-EELEEDLHKLEEALNdlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ 841

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1440 LRrglglgrapspaprpvpgspardapaegsgeglnspSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELR 1519
Cdd:TIGR02169  842 RI------------------------------------DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG 885

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*.
gi 2462515701 1520 SAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEE 1565
Cdd:TIGR02169  886 DLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE 931
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 602-824 9.42e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 9.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  602 SREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKE 681
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  682 LVEVREALSR--ATLQRDMLQAEKAEV--AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNR 757
Cdd:COG4942     99 LEAQKEELAEllRALYRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462515701  758 LVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPT 824
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 846-1080 9.75e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 9.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  846 REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEAtrlrlekEALEGSLFEVQRQLAQLEA 925
Cdd:COG4942     25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL-------AALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  926 RREQLEAEGQALLLAKETLtGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRA---AHEEDLQRLQREK 1002
Cdd:COG4942     98 ELEAQKEELAELLRALYRL-GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAelaALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462515701 1003 EAAWRELEAERAQLQsQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMG 1080
Cdd:COG4942    177 EALLAELEEERAALE-ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
979-1380 1.75e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 1.75e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  979 EAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEelLARLEAEKEELSEEIAALQQERDEgLLLAES 1058
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE--LETLEAEIEDLRETIAETEREREE-LAEEVR 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1059 EKQQALSLKESEKTALSEKLMGTRHSLATISL---EMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAqev 1135
Cdd:PRK02224   283 DLRERLEELEEERDDLLAEAGLDDADAEAVEArreELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAE--- 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1136 rRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREAL 1215
Cdd:PRK02224   360 -ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1216 R---RSNEELRSA-------------------------VKKAESERISLKLANEDKEQKLALLEEARTAvGKEAGELRTG 1267
Cdd:PRK02224   439 RervEEAEALLEAgkcpecgqpvegsphvetieedrerVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEER 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1268 LQEVE------RSRLEARRE-LQELRRQMKMLDSEN-------TRLGRELAELQGRLAL--GERAEKESRRETLGLRQRL 1331
Cdd:PRK02224   518 REDLEeliaerRETIEEKRErAEELRERAAELEAEAeekreaaAEAEEEAEEAREEVAElnSKLAELKERIESLERIRTL 597

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462515701 1332 LKGEASLEVMRQELQVAQRKLQEQE-------GEFRTRERRLLGSLEEARGTEKQQ 1380
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNderrerlAEKRERKRELEAEFDEARIEEARE 653
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
645-1290 1.83e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 1.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  645 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELElsm 724
Cdd:PRK03918   158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE--- 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  725 tKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQErleelrleqevarqgL 804
Cdd:PRK03918   235 -ELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK---------------L 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  805 EGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSrQLSGREQELEQARREAQRQVEALERAAREKEalakehaglavq 884
Cdd:PRK03918   299 SEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE-EKEERLEELKKKLKELEKRLEELEERHELYE------------ 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  885 lvaaerEGRTLSEEATRLRLEKEALEgsLFEVQRQLAQLEARREQLEAEgqalllaKETLTGELAGLRqqiiatQEKASL 964
Cdd:PRK03918   366 ------EAKAKKEELERLKKRLTGLT--PEKLEKELEELEKAKEEIEEE-------ISKITARIGELK------KEIKEL 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  965 DKELMaqKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAA 1044
Cdd:PRK03918   425 KKAIE--ELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELA 502

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1045 LQQERDEglllaesEKQQALSLKESEKTAlsEKLMGTRHSLATISLEMERQKRDAQSRQEqdrstvnaLTSELRDLRAQR 1124
Cdd:PRK03918   503 EQLKELE-------EKLKKYNLEELEKKA--EEYEKLKEKLIKLKGEIKSLKKELEKLEE--------LKKKLAELEKKL 565

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1125 EEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELleaqRKLRESQEGREVQRQEAGELRRS 1204
Cdd:PRK03918   566 DELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREE----KELKKLEEELDKAFEELAETEKR 641

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1205 LGEGAKEREALRRSNEELRSAVKKAESERISLKLANedKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLE------A 1278
Cdd:PRK03918   642 LEELRKELEELEKKYSEEEYEELREEYLELSRELAG--LRAELEELEKRREEIKKTLEKLKEELEEREKAKKEleklekA 719

                          650
                   ....*....|..
gi 2462515701 1279 RRELQELRRQMK 1290
Cdd:PRK03918   720 LERVEELREKVK 731
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 528-1377 1.93e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.13  E-value: 1.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  528 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHE---------------DAQREVQ 592
Cdd:TIGR00606  250 LKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYhnhqrtvrekerelvDCQRELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  593 RLRSANELLSREKSNLahslqVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQeDAVQDGARVRRELERSHR-QLEQL 671
Cdd:TIGR00606  330 KLNKERRLLNQEKTEL-----LVEQGRLQLQADRHQEHIRARDSLIQSLATRLEL-DGFERGPFSERQIKNFHTlVIERQ 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  672 EGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEAL----TKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNES 747
Cdd:TIGR00606  404 EDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIelkkEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  748 LAQ-DKLDLNRLVAQLEEEKSALQGRQ----RQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQA-------- 814
Cdd:TIGR00606  484 ERElSKAEKNSLTETLKKEVKSLQNEKadldRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKsrhsdelt 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  815 --------QEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQvealeraaREKEALAKEHAGLAVQLV 886
Cdd:TIGR00606  564 sllgyfpnKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESK--------EEQLSSYEDKLFDVCGSQ 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  887 AAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQI-IATQEKASLD 965
Cdd:TIGR00606  636 DEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLrLAPDKLKSTE 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  966 KELmaqKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQrEQEELLARLEAEKEELSEEIAAL 1045
Cdd:TIGR00606  716 SEL---KKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIE-EQETLLGTIMPEEESAKVCLTDV 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1046 QQERDEGLLLAESEKQQALSLKESEK-------TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD---RSTVNALTS 1115
Cdd:TIGR00606  792 TIMERFQMELKDVERKIAQQAAKLQGsdldrtvQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIqhlKSKTNELKS 871

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1116 ELRDLRAQREEAAAahaqevrrLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQR 1195
Cdd:TIGR00606  872 EKLQIGTNLQRRQQ--------FEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKV 943

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1196 QEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKlalleeartavgKEAGELRTGLQEVERSR 1275
Cdd:TIGR00606  944 NDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQE------------KINEDMRLMRQDIDTQK 1011

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1276 LEARRELQELRRQMKmlDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQ---ELQVAQRKL 1352
Cdd:TIGR00606 1012 IQERWLQDNLTLRKR--ENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQkgyEKEIKHFKK 1089

                          890       900
                   ....*....|....*....|....*
gi 2462515701 1353 QEQEGEFRTRERRLLGSLEEARGTE 1377
Cdd:TIGR00606 1090 ELREPQFRDAEEKYREMMIVMRTTE 1114
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
615-1223 2.03e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  615 AQQQAEELRQEREKLqaaqEELRRQRDRLEEEQEDA-VQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRAT 693
Cdd:COG4913    240 AHEALEDAREQIELL----EPIRELAERYAAARERLaELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  694 LQRDMLQAEKAEVAEALTKAEAGRVElelsmtKLRAEEASLQDSLSKLSALNESLAQDkldLNRLVAQLEEEKSALQGRQ 773
Cdd:COG4913    316 ARLDALREELDELEAQIRGNGGDRLE------QLEREIERLERELEERERRRARLEAL---LAALGLPLPASAEEFAALR 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  774 RQAEQeatvareeqerleelrleqevARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 853
Cdd:COG4913    387 AEAAA---------------------LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLAL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  854 RREAQRQVEALERAA---------REKEA------------------LAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 906
Cdd:COG4913    446 RDALAEALGLDEAELpfvgelievRPEEErwrgaiervlggfaltllVPPEHYAAALRWVNRLHLRGRLVYERVRTGLPD 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  907 E----ALEGSLFE------------VQRQLAQLEARR-----EQLEAEGQALllakeTLTGELAG-------------LR 952
Cdd:COG4913    526 PerprLDPDSLAGkldfkphpfrawLEAELGRRFDYVcvdspEELRRHPRAI-----TRAGQVKGngtrhekddrrriRS 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  953 QQII---ATQEKASLDKEL-MAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ-SQLQREQEEL 1027
Cdd:COG4913    601 RYVLgfdNRAKLAALEAELaELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREiAELEAELERL 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1028 ------LARLEAEKEELSEEIAALQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQS 1101
Cdd:COG4913    681 dassddLAALEEQLEELEAELEELEEELDE-LKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1102 RQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDardglrRELLEAQ 1181
Cdd:COG4913    760 GDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEE------DGLPEYE 833

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 2462515701 1182 RKLRESQEGREVQRQE--AGELRRSLGEGakeREALRRSNEELR 1223
Cdd:COG4913    834 ERFKELLNENSIEFVAdlLSKLRRAIREI---KERIDPLNDSLK 874
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
810-1332 2.48e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 2.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  810 VAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQlsgREQElEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAE 889
Cdd:PRK02224   196 IEEKEEKDLHERLNGLESELAELDEEIERYEEQ---REQA-RETRDEADEVLEEHEERREELETLEAEIEDLRETIAETE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  890 REGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKAsldkELM 969
Cdd:PRK02224   272 REREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEA----ESL 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  970 AQKLVQAEREAqASLREQRAAHEEDLQrlqrEKEAAWRELEAERAQLQSQLqREQEELLARLEAEKEELSEEIAALQQER 1049
Cdd:PRK02224   348 REDADDLEERA-EELREEAAELESELE----EAREAVEDRREEIEELEEEI-EELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1050 DEgllLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRdaQSRQEQDRSTVNALTSELRDLRAQREEAAA 1129
Cdd:PRK02224   422 DE---LREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPH--VETIEEDRERVEELEAELEDLEEEVEEVEE 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1130 ---------AHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGE 1200
Cdd:PRK02224   497 rleraedlvEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAE 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1201 LRRSLGEGAKEREALRRSnEELRSAVKKAESERISLklaNEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLE-AR 1279
Cdd:PRK02224   577 LNSKLAELKERIESLERI-RTLLAAIADAEDEIERL---REKREALAELNDERRERLAEKRERKRELEAEFDEARIEeAR 652

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462515701 1280 RELQELRRQMKMLDSENTRLGRELAELQGRL-----ALGERAEKESRRETLGLRQRLL 1332
Cdd:PRK02224   653 EDKERAEEYLEQVEEKLDELREERDDLQAEIgavenELEELEELRERREALENRVEAL 710
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 965-1299 2.87e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.43  E-value: 2.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  965 DKELMAQKLVQAEREAQASLREQRAAHEE-DLQRLQREKEAAWRELEAERAQLQSQLQREQEellaRLEAEKEELSEEIA 1043
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERRRKLEEAEKARQAE----MDRQAAIYAEQERM 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1044 ALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHslatisLEMERQKRDAQSRQEQDRSTVNALTSELRDlraq 1123
Cdd:pfam17380  343 AMERERELERIRQEERKRELERIRQEEIAMEISRMRELER------LQMERQQKNERVRQELEAARKVKILEEERQ---- 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1124 reeaaaahaqevRRLQEQARDLGKQRdsclREAEELRT-QLRLLEDARDglrRELLEAQRKLRESQEGREVQRQEAGELR 1202
Cdd:pfam17380  413 ------------RKIQQQKVEMEQIR----AEQEEARQrEVRRLEEERA---REMERVRLEEQERQQQVERLRQQEEERK 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1203 RSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLAL-LEEARTAVGKEAGELRTGLQEVERSRLEARRE 1281
Cdd:pfam17380  474 RKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKeMEERQKAIYEEERRREAEEERRKQQEMEERRR 553

                          330
                   ....*....|....*...
gi 2462515701 1282 LQElrrQMKMLDSENTRL 1299
Cdd:pfam17380  554 IQE---QMRKATEERSRL 568
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 809-1423 3.15e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 3.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  809 RVAEQAQEALEQQLPTLRHERSQLQ-----------EQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKE 877
Cdd:pfam15921  134 RRESQSQEDLRNQLQNTVHELEAAKclkedmledsnTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTM 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  878 HaglavqlvaAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEA---------------RREQL----EAEGQALL 938
Cdd:pfam15921  214 H---------FRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSesqnkielllqqhqdRIEQLisehEVEITGLT 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  939 LAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAE---REAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQ 1015
Cdd:pfam15921  285 EKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLEstvSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTE 364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1016 lQSQLQREQEELLARLeaekeelseeiaalqqerdEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQ 1095
Cdd:pfam15921  365 -RDQFSQESGNLDDQL-------------------QKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDR 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1096 KRDAQSRQeqdrSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDArdglRR 1175
Cdd:pfam15921  425 NMEVQRLE----ALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESS----ER 496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1176 ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAvkKAESERISLKLANEDK-----EQKLALL 1250
Cdd:pfam15921  497 TVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNV--QTECEALKLQMAEKDKvieilRQQIENM 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1251 EEARTAVGKEAGELRTGLQEVERSRLEARRELQELR-------RQMKMLDSENTRLGRELAELQGRLALGERAEKESRRE 1323
Cdd:pfam15921  575 TQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKilkdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQE 654

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1324 TLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGL 1403
Cdd:pfam15921  655 RDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQK 734

                          650       660
                   ....*....|....*....|
gi 2462515701 1404 RLSAAEGRAQGLEAELARVE 1423
Cdd:pfam15921  735 QITAKRGQIDALQSKIQFLE 754
PTZ00121 PTZ00121
MAEBL; Provisional
 1207-1965 3.53e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 3.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1207 EGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARtavgkeagELRTGLQEVERSRLEARRELQELR 1286
Cdd:PTZ00121  1057 EGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAK--------KTETGKAEEARKAEEAKKKAEDAR 1128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1287 RQMKMLDSENTRLGREL--AELQGRLALGERAEKESRRETLGLRQRLLKGEAS---LEVMR-QELQVAQRKLQEQEGEFR 1360
Cdd:PTZ00121  1129 KAEEARKAEDARKAEEArkAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAArkaEEVRKaEELRKAEDARKAEAARKA 1208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1361 TRERRLlgslEEARGTEkqqlDHARGLELKleaaraeaaelglrlSAAEGRAQGLEAElaRVEVQRRAAEAqlgglrsal 1440
Cdd:PTZ00121  1209 EEERKA----EEARKAE----DAKKAEAVK---------------KAEEAKKDAEEAK--KAEEERNNEEI--------- 1254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1441 rRGLGLGRAPSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRS 1520
Cdd:PTZ00121  1255 -RKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADA 1333

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1521 AQRERDELRTQTSAlnrQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGrlSGVQAELALQEESVRRSERERRATLD 1600
Cdd:PTZ00121  1334 AKKKAEEAKKAAEA---AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA--AKKKAEEKKKADEAKKKAEEDKKKAD 1408

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1601 QVATLERSLQATESELRASQEKiskMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQaq 1680
Cdd:PTZ00121  1409 ELKKAAAAKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK-- 1483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1681 alqdRVDSLQRQVADSEVKAGTLQLTVERLNGA--LAKVEESEGAlrDKVRGLTEALAQSSASLNSTRDKNLHLQKA--L 1756
Cdd:PTZ00121  1484 ----KADEAKKKAEEAKKKADEAKKAAEAKKKAdeAKKAEEAKKA--DEAKKAEEAKKADEAKKAEEKKKADELKKAeeL 1557

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1757 TACEHDRQVLQ-----ERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALN 1831
Cdd:PTZ00121  1558 KKAEEKKKAEEakkaeEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQ 1637

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1832 TVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLT 1911
Cdd:PTZ00121  1638 LKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK 1717

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462515701 1912 GAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQ 1965
Cdd:PTZ00121  1718 AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771
mukB PRK04863
chromosome partition protein MukB;
523-1308 4.26e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 52.27  E-value: 4.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  523 LIHSALHKRQlQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLS 602
Cdd:PRK04863   284 HLEEALELRR-ELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  603 ReksnLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQE-------------DAVQDGARVRRELERSHRQLE 669
Cdd:PRK04863   363 R----LEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQaldvqqtraiqyqQAVQALERAKQLCGLPDLTAD 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  670 QLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA--EVAEALTKAEAGRV----------ELELSMTKLRAEEASLQDS 737
Cdd:PRK04863   439 NAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSqfEQAYQLVRKIAGEVsrseawdvarELLRRLREQRHLAEQLQQL 518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  738 LSKLSALNESLAQDKlDLNRLVAQLE-----EEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAE 812
Cdd:PRK04863   519 RMRLSELEQRLRQQQ-RAERLLAEFCkrlgkNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQR 597

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  813 ---------QAQEALEQqLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREkeaLAKEHAGLAV 883
Cdd:PRK04863   598 laarapawlAAQDALAR-LREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIER---LSQPGGSEDP 673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  884 QLVA-AER-EGRTLSEEATRLRLEK----EALEG---------SLFEVQRQLAQLEARREQL---------------EAE 933
Cdd:PRK04863   674 RLNAlAERfGGVLLSEIYDDVSLEDapyfSALYGparhaivvpDLSDAAEQLAGLEDCPEDLyliegdpdsfddsvfSVE 753

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  934 GQALLLAKETLTGELAGLRQQIIATQEKASLDKELmaqKLVQAEREAQASLREQRAAHEEDLQRL--------------- 998
Cdd:PRK04863   754 ELEKAVVVKIADRQWRYSRFPEVPLFGRAAREKRI---EQLRAEREELAERYATLSFDVQKLQRLhqafsrfigshlava 830

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  999 -QREKEAAWRELEAERAQLQSQLQREQEELLaRLEAEKEELSEEIAALQQERDE-GLLLAESEKQQALSLKESEKTALSE 1076
Cdd:PRK04863   831 fEADPEAELRQLNRRRVELERALADHESQEQ-QQRSQLEQAKEGLSALNRLLPRlNLLADETLADRVEEIREQLDEAEEA 909

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1077 KLMGTRHSLATISLE---------------MERQKRDAQSRQEQDRSTVNALTSELRdlraqreeaaaahaqevRRL--- 1138
Cdd:PRK04863   910 KRFVQQHGNALAQLEpivsvlqsdpeqfeqLKQDYQQAQQTQRDAKQQAFALTEVVQ-----------------RRAhfs 972

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1139 -QEQARDLGKQRDSclreAEELRTQLRLLEDARDGLRRELLEAQRKLRES-------QEGREVQRQEAGELRRSLG---- 1206
Cdd:PRK04863   973 yEDAAEMLAKNSDL----NEKLRQRLEQAEQERTRAREQLRQAQAQLAQYnqvlaslKSSYDAKRQMLQELKQELQdlgv 1048

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1207 ---EGAKEREALRRsnEELRSAVKKAESERISLklanedkEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQ 1283
Cdd:PRK04863  1049 padSGAEERARARR--DELHARLSANRSRRNQL-------EKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAGWC 1119

                          890       900
                   ....*....|....*....|....*
gi 2462515701 1284 ELRRQMKMLDSENTRLGRELAELQG 1308
Cdd:PRK04863  1120 AVLRLVKDNGVERRLHRRELAYLSA 1144
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 542-1358 4.38e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.97  E-value: 4.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  542 YEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAmqahEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEE 621
Cdd:TIGR00606  212 LKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPL----KNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  622 LRQEREKLQAAQEElrrqrdRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQ- 700
Cdd:TIGR00606  288 LELKMEKVFQGTDE------QLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQe 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  701 ---AEKAEVAEALTKAEAGRVE----LELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 773
Cdd:TIGR00606  362 hirARDSLIQSLATRLELDGFErgpfSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRT 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  774 RQAEQEATVAREEQERLEELRLEQEVARQG----LEGSLRVAEQAQEALEQQ--LPTLRHERSQLQEQLAQLSRQLSGRE 847
Cdd:TIGR00606  442 IELKKEILEKKQEELKFVIKELQQLEGSSDrileLDQELRKAERELSKAEKNslTETLKKEVKSLQNEKADLDRKLRKLD 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  848 QELEQARRE--AQRQVEALERAAREKEA----LAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLA 921
Cdd:TIGR00606  522 QEMEQLNHHttTRTQMEMLTKDKMDKDEqirkIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELA 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  922 QLEARREQLEAEgqalllaKETLTGELAGLRQQIIATQEKASLDKEL-MAQKLVQAEREAQASLREQRAAHEEDLQRLQR 1000
Cdd:TIGR00606  602 SLEQNKNHINNE-------LESKEEQLSSYEDKLFDVCGSQDEESDLeRLKEEIEKSSKQRAMLAGATAVYSQFITQLTD 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1001 EKEAAWR------ELEAERAQLQSQLQreqeELLARLEAEKEELSEEIAALQQERDEGLLLAESeKQQALSLKESEKTAL 1074
Cdd:TIGR00606  675 ENQSCCPvcqrvfQTEAELQEFISDLQ----SKLRLAPDKLKSTESELKKKEKRRDEMLGLAPG-RQSIIDLKEKEIPEL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1075 SEKLMgtrhslaTISLEMERQKRDAqSRQEQDRSTVNALTSELRDLRAQ---REEAAAAHAQEVRRLQEQARDLgkQRDS 1151
Cdd:TIGR00606  750 RNKLQ-------KVNRDIQRLKNDI-EEQETLLGTIMPEEESAKVCLTDvtiMERFQMELKDVERKIAQQAAKL--QGSD 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1152 CLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGEL---RRSLGEGAKEREALRRSNEELRS---- 1224
Cdd:TIGR00606  820 LDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELkseKLQIGTNLQRRQQFEEQLVELSTevqs 899

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1225 ---AVKKAESERISLKLANED----KEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQE-LRRQMKMLDSEN 1296
Cdd:TIGR00606  900 lirEIKDAKEQDSPLETFLEKdqqeKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDgKDDYLKQKETEL 979

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462515701 1297 TRLGRELAELQGRLALGERAEKESRR--ETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGE 1358
Cdd:TIGR00606  980 NTVNAQLEECEKHQEKINEDMRLMRQdiDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKE 1043
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1511-1977 4.41e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.99  E-value: 4.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1511 LREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQaELALQEESVRR 1590
Cdd:PRK03918   219 LREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIK 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1591 SERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLEL--QRRSLEGELQRS 1668
Cdd:PRK03918   298 LSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeEAKAKKEELERL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1669 RLGLSDR-----EAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEA-----LAQS 1738
Cdd:PRK03918   378 KKRLTGLtpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEhrkelLEEY 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1739 SASLNSTRDKnlhlQKALTACEHDRQVLQERLDAARQALSEARKQsSSLGEQVQTLRGEVADLELQRVEAEGQ----LQQ 1814
Cdd:PRK03918   458 TAELKRIEKE----LKEIEEKERKLRKELRELEKVLKKESELIKL-KELAEQLKELEEKLKKYNLEELEKKAEeyekLKE 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1815 LREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRValrRTLDKVEREKLRSHE 1894
Cdd:PRK03918   533 KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL---KELEPFYNEYLELKD 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1895 DTVRLSAEKGRLDR---TLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLE------VDAQQQQLELQQEVERLRSAQ 1965
Cdd:PRK03918   610 AEKELEREEKELKKleeELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEelreeyLELSRELAGLRAELEELEKRR 689

                          490
                   ....*....|..
gi 2462515701 1966 AQTERTLEARER 1977
Cdd:PRK03918   690 EEIKKTLEKLKE 701
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
534-822 4.52e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 51.06  E-value: 4.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  534 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREksnlahsLQ 613
Cdd:COG4372     32 QLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEE-------LE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  614 VAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRAT 693
Cdd:COG4372    105 SLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQA 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  694 LQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 773
Cdd:COG4372    185 LDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 2462515701  774 RQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQL 822
Cdd:COG4372    265 LAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGAL 313
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1508-1941 5.59e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.88  E-value: 5.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1508 RGALRE---FLQELRSAQRERDELRTQTSALNRQLA----EMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAE 1580
Cdd:COG3096    235 EAALREnrmTLEAIRVTQSDRDLFKHLITEATNYVAadymRHANERRELSERALELRRELFGARRQLAEEQYRLVEMARE 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1581 LALQEESVRRSERERRATLDQVATLERSLQAteselrasQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS 1660
Cdd:COG3096    315 LEELSARESDLEQDYQAASDHLNLVQTALRQ--------QEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEA 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1661 LEGELQRSRLGLSDREAQAQALQDRVDSLQRQV---ADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQ 1737
Cdd:COG3096    387 AEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVqalEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSV 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1738 SSASLNStRDKNLHLQKALTAcEHDRqvlQERLDAARQALSEARKQsSSLGEQVQTLRGEVADLElQRVEAEGQLQQLRE 1817
Cdd:COG3096    467 ADAARRQ-FEKAYELVCKIAG-EVER---SQAWQTARELLRRYRSQ-QALAQRLQQLRAQLAELE-QRLRQQQNAERLLE 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1818 VLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQR----ALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSH 1893
Cdd:COG3096    540 EFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAeaveQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSG 619

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462515701 1894 E---DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPA 1941
Cdd:COG3096    620 EalaDSQEVTAAMQQLLEREREATVERDELAARKQALESQIERLSQPGGAE 670
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1213-1858 8.03e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 8.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1213 EALRRSNEELRSAVKKAES-ERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKM 1291
Cdd:COG4913    255 EPIRELAERYAAARERLAElEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1292 LDsentrlGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEqegefrtrerrLLGSLE 1371
Cdd:COG4913    335 NG------GDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA-----------LLEALE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1372 EARGTEKQQLDHARGlelkleaaraeaaelglRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLgrapS 1451
Cdd:COG4913    398 EELEALEEALAEAEA-----------------ALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGL----D 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1452 PAPRPVPGS----PARDAPAEGSGEG-LNSpstlecspgsqppspgPATSPASPDLDPEAVRGA-----LREFLQELRSA 1521
Cdd:COG4913    457 EAELPFVGElievRPEEERWRGAIERvLGG----------------FALTLLVPPEHYAAALRWvnrlhLRGRLVYERVR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1522 QRERDELRTQTSAlNRQLAEMEAERDSATSRARQL---QKAVA--ESEEARRSVD--------GRLSGVQAELALQEESV 1588
Cdd:COG4913    521 TGLPDPERPRLDP-DSLAGKLDFKPHPFRAWLEAElgrRFDYVcvDSPEELRRHPraitragqVKGNGTRHEKDDRRRIR 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1589 RRSERERRATlDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRS 1668
Cdd:COG4913    600 SRYVLGFDNR-AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1669 RLGLSDR-----EAQAQALQDRVDSLQRQVADSEVKAGTLQltvERLNGALAKVEESEGALRDKVRGLTEALAQSSASLN 1743
Cdd:COG4913    679 RLDASSDdlaalEEQLEELEAELEELEEELDELKGEIGRLE---KELEQAEEELDELQDRLEAAEDLARLELRALLEERF 755

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1744 STRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQ-SSSLGEQVQTLRGEVADLE-----LQRVEAEG---QLQQ 1814
Cdd:COG4913    756 AAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAfNREWPAETADLDADLESLPeylalLDRLEEDGlpeYEER 835

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 2462515701 1815 LREVLRQRQEGEAAALNtvQKLQDERRLLQERLGSLQRALAQLE 1858
Cdd:COG4913    836 FKELLNENSIEFVADLL--SKLRRAIREIKERIDPLNDSLKRIP 877
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 549-1050 8.03e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.38  E-value: 8.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  549 LGTLRKQLSDSESERRALEEQLQRLRDktDGAMQAHEDAQREVQrLRSANELLSREKSNLAHSLQVAQQQAEELRQEREK 628
Cdd:pfam12128  310 LSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLPS-WQSELENLEERLKALTGKHQDVTAKYNRRRSKIKE 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  629 LQAAqeELRRQRDRLEEEQEDAVQDGARVRRELERSHRQL-EQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKaeva 707
Cdd:pfam12128  387 QNNR--DIAGIKDKLAKIREARDRQLAVAEDDLQALESELrEQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATP---- 460

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  708 EALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA------- 780
Cdd:pfam12128  461 ELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAgtllhfl 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  781 -TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE------------------------------ALEQQLPTLRHER 829
Cdd:pfam12128  541 rKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGElnlygvkldlkridvpewaaseeelrerldKAEEALQSAREKQ 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  830 SQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALA----------KEHAGLAVQLVAAEREGRTLSEEA 899
Cdd:pfam12128  621 AAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKdkknkalaerKDSANERLNSLEAQLKQLDKKHQA 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  900 TRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAqKLVQAERE 979
Cdd:pfam12128  701 WLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIA-KLKREIRT 779

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462515701  980 AQASLrEQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERD 1050
Cdd:pfam12128  780 LERKI-ERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERK 849
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
897-1316 8.81e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 8.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  897 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQA 976
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  977 EREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEgLLLA 1056
Cdd:COG4717    154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE-LEQL 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1057 ESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQkrdaqsrqeqdRSTVNALTSELRDLRAQREEAAAAHAQEVR 1136
Cdd:COG4717    233 ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSL-----------ILTIAGVLFLVLGLLALLFLLLAREKASLG 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1137 RLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE-----SQEGREVQRQEAGELRRSLGE--GA 1209
Cdd:COG4717    302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQEllreaEELEEELQLEELEQEIAALLAeaGV 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1210 KEREALRRSNEELRSAVK-KAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQ 1288
Cdd:COG4717    382 EDEEELRAALEQAEEYQElKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAE 461

                          410       420       430
                   ....*....|....*....|....*....|
gi 2462515701 1289 MKMLDSENT--RLGRELAELQGRLALGERA 1316
Cdd:COG4717    462 LEQLEEDGElaELLQELEELKAELRELAEE 491
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
553-770 9.43e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 9.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  553 RKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAE------------ 620
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAElerldassddla 688

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  621 ELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSV-LAKELVEVREALSRATLQRDML 699
Cdd:COG4913    689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFAAALGDAVERELR 768

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462515701  700 QAEKAEVAEALTKAEAGRVELELSMTKLRAE-EASLQDSLSKLSALNESLAQ-DKLDLNRLVAQLEEEKSALQ 770
Cdd:COG4913    769 ENLEERIDALRARLNRAEEELERAMRAFNREwPAETADLDADLESLPEYLALlDRLEEDGLPEYEERFKELLN 841
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
626-1051 1.00e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 1.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  626 REKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAe 705
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ- 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  706 vaealtkaeagrvelelsmtklraeeasLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVARE 785
Cdd:COG4717    127 ----------------------------LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEE 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  786 EQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSG--REQELEQARREAQRQVEA 863
Cdd:COG4717    179 LEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAaaLEERLKEARLLLLIAAAL 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  864 LERAAREKEALAKEHAGLAVQLVAAEregrTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET 943
Cdd:COG4717    259 LALLGLGGSLLSLILTIAGVLFLVLG----LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDL 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  944 LTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 1023
Cdd:COG4717    335 SPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEEL 414

                          410       420
                   ....*....|....*....|....*....
gi 2462515701 1024 QEELLARLEAEKEEL-SEEIAALQQERDE 1051
Cdd:COG4717    415 LGELEELLEALDEEElEEELEELEEELEE 443
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 811-1355 1.10e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.74  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  811 AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAglavqlVAAER 890
Cdd:TIGR00618  210 TPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAV------LEETQ 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  891 EGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEgqalllaketLTGELAGLRQQIIATQEKASLDKELMA 970
Cdd:TIGR00618  284 ERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL----------LMKRAAHVKQQSSIEEQRRLLQTLHSQ 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  971 QKLVQAEREAQASLREQRAAHEEDLQRL--QREKEAAWRELEAERAQLQSQLQREQEELLARLeaekeelseeiaalQQE 1048
Cdd:TIGR00618  354 EIHIRDAHEVATSIREISCQQHTLTQHIhtLQQQKTTLTQKLQSLCKELDILQREQATIDTRT--------------SAF 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1049 RDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAA 1128
Cdd:TIGR00618  420 RDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLEL 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1129 AAHA------------------------QEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL 1184
Cdd:TIGR00618  500 QEEPcplcgscihpnparqdidnpgpltRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCD 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1185 RESQEGREVQRQEAGELRRSLGEGAKEREALR-RSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGE 1263
Cdd:TIGR00618  580 NRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAcEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQER 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1264 LRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQ 1343
Cdd:TIGR00618  660 VREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARED 739

                          570
                   ....*....|..
gi 2462515701 1344 ELQVAQRKLQEQ 1355
Cdd:TIGR00618  740 ALNQSLKELMHQ 751
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1731-1937 1.19e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1731 LTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEG 1810
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1811 QLQQLREVLRQRQEGEAAALNTVQKLQDERRLL----QERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVE 1886
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462515701 1887 REKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQS 1937
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
904-1442 1.29e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 1.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  904 LEKEALEGSLFEVQRQLAQL-EARREQLEAEGQALLLAketltgELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQA 982
Cdd:COG4913    218 LEEPDTFEAADALVEHFDDLeRAHEALEDAREQIELLE------PIRELAERYAAARERLAELEYLRAALRLWFAQRRLE 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  983 SLREQRAAHEEDLQRLQREK---EAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEgllLAESE 1059
Cdd:COG4913    292 LLEAELEELRAELARLEAELerlEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRAR---LEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1060 KQQALSLKESEK--TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRR 1137
Cdd:COG4913    369 AALGLPLPASAEefAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1138 LqeqARDLGKQRDSC--------LREAEE---------LRTQ-LRLLEDARDglRRELLEA--QRKLRESQEGREVQRQE 1197
Cdd:COG4913    449 L---AEALGLDEAELpfvgelieVRPEEErwrgaiervLGGFaLTLLVPPEH--YAAALRWvnRLHLRGRLVYERVRTGL 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1198 AGELRRSLGEGA-------KEREALRRSNEEL--RSAVKKAESERislKLANEDKeqklALLEEARTAVGKEAGELRTGL 1268
Cdd:COG4913    524 PDPERPRLDPDSlagkldfKPHPFRAWLEAELgrRFDYVCVDSPE---ELRRHPR----AITRAGQVKGNGTRHEKDDRR 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1269 QEVE--------RSRLEA-RRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEK------------ESRRETLGL 1327
Cdd:COG4913    597 RIRSryvlgfdnRAKLAAlEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeidvasaeREIAELEAE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1328 RQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRlLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSA 1407
Cdd:COG4913    677 LERLDASSDDLAALEEQLEELEAELEELEEELDELKGE-IGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF 755

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 2462515701 1408 AEGRAQGLEAELAR-VEVQRRAAEAQLGGLRSALRR 1442
Cdd:COG4913    756 AAALGDAVERELREnLEERIDALRARLNRAEEELER 791
PTZ00121 PTZ00121
MAEBL; Provisional
 970-1729 1.31e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 1.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  970 AQKLVQAEREAQASLREQRAAHEEDLQRLQ--REKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQ 1047
Cdd:PTZ00121  1096 AFGKAEEAKKTETGKAEEARKAEEAKKKAEdaRKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDA 1175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1048 ERDEGLLLAEsEKQQALSLKESEKTalseklmgtRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEA 1127
Cdd:PTZ00121  1176 KKAEAARKAE-EVRKAEELRKAEDA---------RKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKA 1245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1128 AAAHAQEVRRLQEQARDLGKQRDSCLREAEELRT--QLRLLEDARDGLRRELLEAQRKLRESQEGREvQRQEAGELRRSL 1205
Cdd:PTZ00121  1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKadELKKAEEKKKADEAKKAEEKKKADEAKKKAE-EAKKADEAKKKA 1324

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1206 GEGAKEREALRRSNEELRSA--VKKAESERISLKLANEDKEQKLAllEEARTAVGKEAGELRTGLQEVERSRlEARRELQ 1283
Cdd:PTZ00121  1325 EEAKKKADAAKKKAEEAKKAaeAAKAEAEAAADEAEAAEEKAEAA--EKKKEEAKKKADAAKKKAEEKKKAD-EAKKKAE 1401

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1284 ELRRQMKmldsentRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1363
Cdd:PTZ00121  1402 EDKKKAD-------ELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1364 rrLLGSLEEARGTEkqqldharglELKLEAARAEAAELGLRLSAAEGRAQgleAELARVEVQRRAAEAQlgglrsalrrg 1443
Cdd:PTZ00121  1475 --AKKKAEEAKKAD----------EAKKKAEEAKKKADEAKKAAEAKKKA---DEAKKAEEAKKADEAK----------- 1528

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1444 lglgrapsPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATspaspdldpEAVRGALREFLQELRSAQR 1523
Cdd:PTZ00121  1529 --------KAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA---------EEDKNMALRKAEEAKKAEE 1591

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1524 ERDElrtqtsalnrqlAEMEAERDSATSRARQLQKAvaesEEARRSVDGRLSGVQAELALQEESVRRSERERRAtlDQVA 1603
Cdd:PTZ00121  1592 ARIE------------EVMKLYEEEKKMKAEEAKKA----EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKA--EELK 1653

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1604 TLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRS---RLGLSDREAQAQ 1680
Cdd:PTZ00121  1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAeelKKAEEENKIKAE 1733

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2462515701 1681 ALQDRVDSLQRQV----ADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVR 1729
Cdd:PTZ00121  1734 EAKKEAEEDKKKAeeakKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 542-1100 1.38e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.49  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  542 YEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSReksnlahSLQVAQQQAEE 621
Cdd:pfam05483  221 HEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDE-------NLKELIEKKDH 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  622 LRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRaTLQRDMLQA 701
Cdd:pfam05483  294 LTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEE-LLRTEQQRL 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  702 EKAEVAEALTKAEAGRVELELS-MTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 780
Cdd:pfam05483  373 EKNEDQLKIITMELQKKSSELEeMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEI 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  781 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQR- 859
Cdd:pfam05483  453 HDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERm 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  860 --QVEALERAARE--------KEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQ 929
Cdd:pfam05483  533 lkQIENLEEKEMNlrdelesvREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEE 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  930 LEAEGQALllaKETLTGELAGLRQQIIATQeKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAwrel 1009
Cdd:pfam05483  613 LHQENKAL---KKKGSAENKQLNAYEIKVN-KLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIA---- 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1010 eAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSE---KLMGTRHSLA 1086
Cdd:pfam05483  685 -DEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNikaELLSLKKQLE 763

                          570
                   ....*....|....
gi 2462515701 1087 TISLEMERQKRDAQ 1100
Cdd:pfam05483  764 IEKEEKEKLKMEAK 777
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
76-258 1.60e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.02  E-value: 1.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   76 LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASY 155
Cdd:COG3206    207 LVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARY 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  156 RRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQV 235
Cdd:COG3206    287 TPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVAREL 366

                          170       180
                   ....*....|....*....|...
gi 2462515701  236 NAMLREQLDQAGSANQALSEDIR 258
Cdd:COG3206    367 YESLLQRLEEARLAEALTVGNVR 389
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 559-1031 1.77e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 50.18  E-value: 1.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  559 SESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELlSREKSNLAHSLQVAQQQAEELRQEREKLQAAQ--EEL 636
Cdd:PRK10246   214 TPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDEL-QQEASRRQQALQQALAAEEKAQPQLAALSLAQpaRQL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  637 RRQRDRLEEeQEDAVqdgARVRRELERSHRQLEQLEGKRSvlakelvEVREALSRatlQRDMLQAEKAEVAEALTKAEAG 716
Cdd:PRK10246   293 RPHWERIQE-QSAAL---AHTRQQIEEVNTRLQSTMALRA-------RIRHHAAK---QSAELQAQQQSLNTWLAEHDRF 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  717 RVeLELSMTKLRAEEASLQDSLSKLSALNESLAQDKldlnrlvaqleeeksalqgRQRQAEQEATVAREEQERLeelrle 796
Cdd:PRK10246   359 RQ-WNNELAGWRAQFSQQTSDREQLRQWQQQLTHAE-------------------QKLNALPAITLTLTADEVA------ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  797 qevARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARRE--AQRQVEALERAAREKEAL 874
Cdd:PRK10246   413 ---AALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRykEKTQQLADVKTICEQEAR 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  875 AK---------------------EHAGL----AVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQ 929
Cdd:PRK10246   490 IKdleaqraqlqagqpcplcgstSHPAVeayqALEPGVNQSRLDALEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQS 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  930 LEAEGQALLLAKETLTGELAGLR-----------------QQIIATQEKASLDKELMAQKlvQAEREAQASLREQRAAHE 992
Cdd:PRK10246   570 LRQEEQALTQQWQAVCASLNITLqpqddiqpwldaqeeheRQLRLLSQRHELQGQIAAHN--QQIIQYQQQIEQRQQQLL 647

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 2462515701  993 EDLQRL-----QREKEAAWRELEAERAQLQSQLQREQEELLARL 1031
Cdd:PRK10246   648 TALAGYaltlpQEDEEASWLATRQQEAQSWQQRQNELTALQNRI 691
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 528-843 2.17e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.63  E-value: 2.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  528 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSN 607
Cdd:TIGR04523  365 LEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKD 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  608 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQdgarvrrELERSHRQLEQLEGKRSVLAKELVEVRE 687
Cdd:TIGR04523  445 LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK-------ELKSKEKELKKLNEEKKELEEKVKDLTK 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  688 ALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTK--LRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEE 765
Cdd:TIGR04523  518 KISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKenLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKE 597

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462515701  766 KSALqgRQRQAEQEATVAReeqerleelrleqevarqgLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQL 843
Cdd:TIGR04523  598 KKDL--IKEIEEKEKKISS-------------------LEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1516-1744 2.72e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1516 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERER 1595
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1596 RATLDQVATLERSLQATES----ELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLG 1671
Cdd:COG4942    100 EAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462515701 1672 LSDREAQAQALQDRVDSLQRQVADsevkagtLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNS 1744
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLAR-------LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1768-1999 3.24e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.28  E-value: 3.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1768 ERLDAARQALSEARKqsSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERL 1847
Cdd:TIGR02168  213 ERYKELKAELRELEL--ALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1848 GSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQL 1927
Cdd:TIGR02168  291 YALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462515701 1928 EAQVVVLEQSHSPAQLEV-DAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVSTLKGQLQQELRRSSA 1999
Cdd:TIGR02168  371 ESRLEELEEQLETLRSKVaQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELE 443
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1505-1976 3.29e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.30  E-value: 3.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1505 EAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQ 1584
Cdd:TIGR02169  304 ASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAET 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1585 EESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAD 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTV-----------ERLNGAL--------------AKVEE 1719
Cdd:TIGR02169  464 LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVrggraveevlkASIQGVHgtvaqlgsvgeryaTAIEV 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1720 SEGALRDKVRGLTEALAQSSAS--------------LNSTRDKNLHLQK---------ALTACEHDRQ------------ 1764
Cdd:TIGR02169  544 AAGNRLNNVVVEDDAVAKEAIEllkrrkagratflpLNKMRDERRDLSIlsedgvigfAVDLVEFDPKyepafkyvfgdt 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1765 VLQERLDAARQALSEARkqssslgeqVQTLRGEVadLELQRVEAEGQLQQLREVLRQRQEGEAAAL--NTVQKLQDERRL 1842
Cdd:TIGR02169  624 LVVEDIEAARRLMGKYR---------MVTLEGEL--FEKSGAMTGGSRAPRGGILFSRSEPAELQRlrERLEGLKRELSS 692

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1843 LQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQR 1922
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEE 772

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2462515701 1923 QIQQLEAQVVVLEQSHSPAQLEvDAQQQQLELQQEVERLRSAQAQTERTLEARE 1976
Cdd:TIGR02169  773 DLHKLEEALNDLEARLSHSRIP-EIQAELSKLEEEVSRIEARLREIEQKLNRLT 825
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 527-873 3.42e-05

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 48.53  E-value: 3.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  527 ALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKS 606
Cdd:pfam19220    7 LLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  607 NLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 686
Cdd:pfam19220   87 ELVARLAKLEAALREAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATAR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  687 EALSRATLQRDMLQAEKAEVAEALTKAEAgrvelelsmtKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 766
Cdd:pfam19220  167 ERLALLEQENRRLQALSEEQAAELAELTR----------RLAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEAV 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  767 SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLsgr 846
Cdd:pfam19220  237 EAHRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQF--- 313

                          330       340
                   ....*....|....*....|....*..
gi 2462515701  847 eQELEQARREAQRQVEALERAAREKEA 873
Cdd:pfam19220  314 -QEMQRARAELEERAEMLTKALAAKDA 339
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 801-1011 3.72e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 3.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  801 RQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEhag 880
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE--- 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  881 LAVQLVAAEREGRT-------LSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQ 953
Cdd:COG4942    106 LAELLRALYRLGRQpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  954 QIIATQEKASLDKELMAQ--KLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEA 1011
Cdd:COG4942    186 ERAALEALKAERQKLLARleKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 552-852 3.93e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.86  E-value: 3.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  552 LRKQLSDSESERRALEEQLQRLRDKTdgamqahEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQA 631
Cdd:TIGR04523  347 LKKELTNSESENSEKQRELEEKQNEI-------EKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQ 419

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  632 AQEELRRQRDRLEEEQEDAVQDGARVRRE----------LERSHRQLEQ----LEGKRSVLAKELVEVREALSRATLQRD 697
Cdd:TIGR04523  420 EKELLEKEIERLKETIIKNNSEIKDLTNQdsvkeliiknLDNTRESLETqlkvLSRSINKIKQNLEQKQKELKSKEKELK 499

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  698 MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQdslSKLSALNESLAQDKLDLNRlvAQLEEEKSALQGRQRQAE 777
Cdd:TIGR04523  500 KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKE---SKISDLEDELNKDDFELKK--ENLEKEIDEKNKEIEELK 574

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462515701  778 QEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQ 852
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1608-1829 4.20e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 4.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1608 SLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVD 1687
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1688 SLQRQVADSEVKAGTLQLTVERLngALAKVEESEGALR--DKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQV 1765
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLA--LLLSPEDFLDAVRrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462515701 1766 LQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAA 1829
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
527-653 4.53e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 4.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  527 ALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKS 606
Cdd:COG4913    665 SAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR 744

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462515701  607 NLAHSL---QVAQQQAEELRQE-REKLQAAQEELRRQRDRLEEEQEDAVQD 653
Cdd:COG4913    745 LELRALleeRFAAALGDAVERElRENLEERIDALRARLNRAEEELERAMRA 795
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1135-1697 5.06e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 5.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1135 VRRLQEQARDLGKQRDSClREAEELRTQLRLLEDARDGLRreLLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREA 1214
Cdd:COG4913    244 LEDAREQIELLEPIRELA-ERYAAARERLAELEYLRAALR--LWFAQRRLELLEAELEELRAELARLEAELERLEARLDA 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1215 LRRSNEELRSAVKKAESERI-SLKLANEDKEQKLALLEEARTAVGKEAGELR----TGLQEVERSRLEARRELQELRRQM 1289
Cdd:COG4913    321 LREELDELEAQIRGNGGDRLeQLEREIERLERELEERERRRARLEALLAALGlplpASAEEFAALRAEAAALLEALEEEL 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1290 KMLDSENTRLGRELAELQGRLA--LGERAEKESRRETLGLRQRLLKGE--ASLEVMRQELQVAQRKLQEQEGE------- 1358
Cdd:COG4913    401 EALEEALAEAEAALRDLRRELRelEAEIASLERRKSNIPARLLALRDAlaEALGLDEAELPFVGELIEVRPEEerwrgai 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1359 ------FRTR-------ERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQG-LEAELA-RVE 1423
Cdd:COG4913    481 ervlggFALTllvppehYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwLEAELGrRFD 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1424 VQRRAAEAQLGGLRSAL-RRGLG--------LGRAPSPAPRPVPGSPARDApaegsgeglnspstlecspgsqppspgpa 1494
Cdd:COG4913    561 YVCVDSPEELRRHPRAItRAGQVkgngtrheKDDRRRIRSRYVLGFDNRAK----------------------------- 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1495 tspaspdldpeavrgaLREFLQELRSAQRERDELRTQTSALNRQLAEMEAERdsatsRARQLQKAVAESEEARRSVDGRL 1574
Cdd:COG4913    612 ----------------LAALEAELAELEEELAEAEERLEALEAELDALQERR-----EALQRLAEYSWDEIDVASAEREI 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1575 SGVQAELAlqeesvrrserERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESR---T 1651
Cdd:COG4913    671 AELEAELE-----------RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRleaA 739

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 2462515701 1652 VKLELQRRSLEGELQRSRLGLSDREAQ-AQALQDRVDSLQRQVADSE 1697
Cdd:COG4913    740 EDLARLELRALLEERFAAALGDAVERElRENLEERIDALRARLNRAE 786
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
603-1031 5.17e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.23  E-value: 5.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  603 REKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQE--DAVQDGARVRRELERSHRQLEQLEGKRsvlaK 680
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEELEERL----E 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  681 ELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVE-LELSMTKLRAEEASLQDSLSKLSALNESLAQDkldlnrlV 759
Cdd:COG4717    157 ELRELEEELEELEAELAELQEELEELLEQLSLATEEELQdLAEELEELQQRLAELEEELEEAQEELEELEEE-------L 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  760 AQLEEEKSALQGRQRQAEQEAT-VAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQ 838
Cdd:COG4717    230 EQLENELEAAALEERLKEARLLlLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQA 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  839 LSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQR 918
Cdd:COG4717    310 LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRA 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  919 QLAQLEARREQLEAegqaLLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRL 998
Cdd:COG4717    390 ALEQAEEYQELKEE----LEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL 465

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462515701  999 Q-------------------REKEAAWRELEAERAQLQSQLQREQEELLARL 1031
Cdd:COG4717    466 EedgelaellqeleelkaelRELAEEWAALKLALELLEEAREEYREERLPPV 517
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 867-1068 5.50e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 5.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  867 AAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTG 946
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  947 ELAGLRQQI---IATQEKASLDKELM----AQKLVQAEREAQ--ASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ 1017
Cdd:COG4942     98 ELEAQKEELaelLRALYRLGRQPPLAlllsPEDFLDAVRRLQylKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462515701 1018 SQLQrEQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKE 1068
Cdd:COG4942    178 ALLA-ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1517-1939 6.10e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 6.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1517 ELRSAQRERDELRTQTSALNRQLAEMEAE---RDSATSRARQLQKAVAESEEA--------RRSVDGR----------LS 1575
Cdd:pfam15921  357 ELTEARTERDQFSQESGNLDDQLQKLLADlhkREKELSLEKEQNKRLWDRDTGnsitidhlRRELDDRnmevqrlealLK 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1576 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMK----ANETKLEGDKRRLKEVLDASESRT 1651
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKmtleSSERTVSDLTASLQEKERAIEATN 516

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1652 VKLELQRRSLEGELQRSRlGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGL 1731
Cdd:pfam15921  517 AEITKLRSRVDLKLQELQ-HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL 595

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1732 TEALAQSSASLNS---TRDKNLHLQKALTACEHDRQVLQ--------ERLDAAR-------QALSE---ARKQSSSLGEQ 1790
Cdd:pfam15921  596 EKEINDRRLELQEfkiLKDKKDAKIRELEARVSDLELEKvklvnagsERLRAVKdikqerdQLLNEvktSRNELNSLSED 675

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1791 VQTLRGEVAD-----------LELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERR-------LLQERLGSLQR 1852
Cdd:pfam15921  676 YEVLKRNFRNkseemetttnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITakrgqidALQSKIQFLEE 755

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1853 ALAQLEAEKR--EVERSALRLEKDRVALRRTLDKVEREKLRSHEDtvRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQ 1930
Cdd:pfam15921  756 AMTNANKEKHflKEEKNKLSQELSTVATEKNKMAGELEVLRSQER--RLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833


                   ....*....
gi 2462515701 1931 VVVLEQSHS 1939
Cdd:pfam15921  834 SVRLKLQHT 842
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 546-1294 7.30e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.86  E-value: 7.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  546 QDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQE 625
Cdd:pfam01576  221 QEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEE 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  626 REKLQ----------AAQEELRRQRDRLEEEQEDAVQDGARVR------------RELERSHRQLEQ------------- 670
Cdd:pfam01576  301 LEALKteledtldttAAQQELRSKREQEVTELKKALEEETRSHeaqlqemrqkhtQALEELTEQLEQakrnkanlekakq 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  671 -LEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLA 749
Cdd:pfam01576  381 aLESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLS 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  750 QDkldLNRLVAQLEEEKSALQGRQRQAEQEATvareeqerleeLRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHER 829
Cdd:pfam01576  461 KD---VSSLESQLQDTQELLQEETRQKLNLST-----------RLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQL 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  830 SQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEAL 909
Cdd:pfam01576  527 SDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKF 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  910 EGSLFEVQRQLAQLEARREQLEAEgqalllAKETLTGELAGLRQQIIATQEKASLDKelmAQKLVQAEREAQASlreqra 989
Cdd:pfam01576  607 DQMLAEEKAISARYAEERDRAEAE------AREKETRALSLARALEEALEAKEELER---TNKQLRAEMEDLVS------ 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  990 aHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELlarleaekeelseeiaalqQERDEGLLLAESEKQQALSLKES 1069
Cdd:pfam01576  672 -SKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL-------------------QATEDAKLRLEVNMQALKAQFER 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1070 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEV---RRLQEQARDLG 1146
Cdd:pfam01576  732 DLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVkqlKKLQAQMKDLQ 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1147 KQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAV 1226
Cdd:pfam01576  812 RELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARI 891

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462515701 1227 KKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDS 1294
Cdd:pfam01576  892 AQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEG 959
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 551-1078 7.48e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.71  E-value: 7.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  551 TLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANE---LLSREKSNLAHSLQVAQQQAEELRQERE 627
Cdd:TIGR04523  163 DLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEIN 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  628 KLQAAQEELRRQRDRLEEEQEdavqdgaRVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRatlqrdmLQAEKAEVA 707
Cdd:TIGR04523  243 EKTTEISNTQTQLNQLKDEQN-------KIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISD-------LNNQKEQDW 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  708 EALTKAEagrvelelsmtkLRAEEASLQDSLSKLSALNESLAQdkldLNRLVAQLEEEKSAL----QGRQRQAEQEatva 783
Cdd:TIGR04523  309 NKELKSE------------LKNQEKKLEEIQNQISQNNKIISQ----LNEQISQLKKELTNSesenSEKQRELEEK---- 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  784 reeqerleelrleqevarqglegslrvaeqaqealEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEA 863
Cdd:TIGR04523  369 -----------------------------------QNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQ 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  864 LERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET 943
Cdd:TIGR04523  414 IKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKS 493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  944 LTGELAGLrqqiiaTQEKASLDKELmaQKLVQaereAQASLREQraahEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 1023
Cdd:TIGR04523  494 KEKELKKL------NEEKKELEEKV--KDLTK----KISSLKEK----IEKLESEKKEKESKISDLEDELNKDDFELKKE 557

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2462515701 1024 QeellarLEAEKEELSEEIAALQQERDEgLLLAESEKQQALSLKESEKTALSEKL 1078
Cdd:TIGR04523  558 N------LEKEIDEKNKEIEELKQTQKS-LKKKQEEKQELIDQKEKEKKDLIKEI 605
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
849-1364 7.76e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 7.76e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  849 ELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEeatrlrlEKEALEGSLFEVQRQLAQLEARRE 928
Cdd:PRK03918   211 EISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEE-------KIRELEERIEELKKEIEELEEKVK 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  929 QLEAegqalLLAKETLTGELAGLRQQIiaTQEKASLDKELmaqklvqaereaqASLREQRAAHEEDLQRLQrEKEAAWRE 1008
Cdd:PRK03918   284 ELKE-----LKEKAEEYIKLSEFYEEY--LDELREIEKRL-------------SRLEEEINGIEERIKELE-EKEERLEE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1009 LEAERAQLQSQLQREQE-----ELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRH 1083
Cdd:PRK03918   343 LKKKLKELEKRLEELEErhelyEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1084 SLATISLEMERQKRD-----AQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDscLREAEE 1158
Cdd:PRK03918   423 ELKKAIEELKKAKGKcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE--LIKLKE 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1159 LRTQLRLLEDARDGLRRELLEaqRKLRESQEGREVQRQEAGELrRSLGEGAKEREALRRSNEELRSAVKKAESERISLK- 1237
Cdd:PRK03918   501 LAEQLKELEEKLKKYNLEELE--KKAEEYEKLKEKLIKLKGEI-KSLKKELEKLEELKKKLAELEKKLDELEEELAELLk 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1238 -------LANEDKEQKLALLEEARtavgKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGR---ELAELQ 1307
Cdd:PRK03918   578 eleelgfESVEELEERLKELEPFY----NEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEElrkELEELE 653

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462515701 1308 GRLAlgERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRER 1364
Cdd:PRK03918   654 KKYS--EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1549-1788 9.17e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1549 ATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKA 1628
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1629 NETKLEGDKRRLKEVLdasESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVE 1708
Cdd:COG4942     91 EIAELRAELEAQKEEL---AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1709 RLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLG 1788
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
700-1231 9.43e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 9.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  700 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQE 779
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  780 ATVAREEQERLEELRLeqevARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAqr 859
Cdd:PRK02224   278 AEEVRDLRERLEELEE----ERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDA-- 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  860 qvEALERAAREKEALAKEhagLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEgqalll 939
Cdd:PRK02224   352 --DDLEERAEELREEAAE---LESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE------ 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  940 aKETLTGELAGLRQQIIATQEKASLDKELMA--------QKLVQAER-EAQASLREQRAAHEEDLQRLQREKEAawRELE 1010
Cdd:PRK02224   421 -RDELREREAELEATLRTARERVEEAEALLEagkcpecgQPVEGSPHvETIEEDRERVEELEAELEDLEEEVEE--VEER 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1011 AERAQLQSQLQREQEELLARleaekeelSEEIAALQQERDEGLllaeSEKQQALSLKESEKTALSEKLMGTRHSLATISL 1090
Cdd:PRK02224   498 LERAEDLVEAEDRIERLEER--------REDLEELIAERRETI----EEKRERAEELRERAAELEAEAEEKREAAAEAEE 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1091 EMERqKRDAQSRQEQDRSTVNALTSELRDLrAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDAR 1170
Cdd:PRK02224   566 EAEE-AREEVAELNSKLAELKERIESLERI-RTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462515701 1171 DGLRRELLEAQR------------KLRESQEGREVQRQEAGELRRSLgegaKEREALRRSNEELRSAVKKAES 1231
Cdd:PRK02224   644 DEARIEEAREDKeraeeyleqveeKLDELREERDDLQAEIGAVENEL----EELEELRERREALENRVEALEA 712
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 511-750 1.21e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  511 PSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQRE 590
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  591 VQRLRSAnelLSREKSNLAHSLQVAQQQAeelRQEREKLQAAQEELRRQRDRLEEEQEDAVQDgarvRRELERSHRQLEQ 670
Cdd:COG4942     92 IAELRAE---LEAQKEELAELLRALYRLG---RQPPLALLLSPEDFLDAVRRLQYLKYLAPAR----REQAEELRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  671 LEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 750
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1505-1994 1.22e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.53  E-value: 1.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1505 EAVRGALREFLQELRSAQRE----RDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSvdgRLSGVQAE 1580
Cdd:pfam12128  279 EERQETSAELNQLLRTLDDQwkekRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQE---QLPSWQSE 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1581 LALQEESVRRSERERRatlDQVATLERSLQATESELRASQEKISKMKANETklEGDKRRLKEVLDASESRTVKLELQRRS 1660
Cdd:pfam12128  356 LENLEERLKALTGKHQ---DVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIR--EARDRQLAVAEDDLQALESELREQLEA 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1661 LEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKagtlqltVERLNGALAKVEESEGALRDKVRGLTEALAQSSA 1740
Cdd:pfam12128  431 GKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENF-------DERIERAREEQEAANAEVERLQSELRQARKRRDQ 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1741 SLNSTRDKNLHLQKALTACEHdrqvLQERLDAARQAL-----SEARKQSSSLGEQVQT-------LRGEVAD-------- 1800
Cdd:pfam12128  504 ASEALRQASRRLEERQSALDE----LELQLFPQAGTLlhflrKEAPDWEQSIGKVISPellhrtdLDPEVWDgsvggeln 579

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1801 -----LELQRVEAEGQLQQLREVLRQRQEGEAAalntvqkLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDR 1875
Cdd:pfam12128  580 lygvkLDLKRIDVPEWAASEEELRERLDKAEEA-------LQSAREKQAAAEEQLVQANGELEKASREETFARTALKNAR 652

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1876 VALRRTLDKVEREKLRSHEDTVRlsaekgrldrtltgaelELAEAQRQIQQLEAQVVVLEQSHSPAQLEVD-----AQQQ 1950
Cdd:pfam12128  653 LDLRRLFDEKQSEKDKKNKALAE-----------------RKDSANERLNSLEAQLKQLDKKHQAWLEEQKeqkreARTE 715

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 2462515701 1951 QLELQQEVERLRSAQ-AQTERTLEARERAHRQRVSTLKGQLQQEL 1994
Cdd:pfam12128  716 KQAYWQVVEGALDAQlALLKAAIAARRSGAKAELKALETWYKRDL 760
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
620-1075 1.26e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 46.82  E-value: 1.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  620 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVevreALSRATLQRDML 699
Cdd:COG5278     79 EPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALV----RSGEGKALMDEI 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  700 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQE 779
Cdd:COG5278    155 RARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALEL 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  780 ATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQR 859
Cdd:COG5278    235 LAALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAA 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  860 QVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLL 939
Cdd:COG5278    315 AAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  940 AKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQ 1019
Cdd:COG5278    395 IAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAAL 474

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462515701 1020 LQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALS 1075
Cdd:COG5278    475 AALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASAEL 530
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 560-877 1.28e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.81  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  560 ESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQ 639
Cdd:pfam07888   72 ERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETE 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  640 RDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVE 719
Cdd:pfam07888  152 LERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAE 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  720 LELSMTKLRAEEASLQDSLSKLSALNESLAQdkLDLNRLVAQLEEEKSALQGRQRQAeQEATVAREEQERLEELRLEQEV 799
Cdd:pfam07888  232 NEALLEELRSLQERLNASERKVEGLGEELSS--MAAQRDRTQAELHQARLQAAQLTL-QLADASLALREGRARWAQERET 308

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462515701  800 ARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKE 877
Cdd:pfam07888  309 LQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
811-1106 1.64e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 46.05  E-value: 1.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  811 AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAER 890
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  891 EGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMA 970
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  971 QKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERD 1050
Cdd:COG4372    189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462515701 1051 EGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD 1106
Cdd:COG4372    269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLEL 324
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1501-1942 1.65e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1501 DLDPEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVA----ESEEARRSVDGRlSG 1576
Cdd:PRK02224   306 DADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAelesELEEAREAVEDR-RE 384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1577 VQAELALQEESVRRSERERRATLDQVATLERSLQATESELRasqEKISKMKANETKLEGDKRRLKEVLDASESRTVKLEL 1656
Cdd:PRK02224   385 EIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELR---EREAELEATLRTARERVEEAEALLEAGKCPECGQPV 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1657 QRRSLEGELQRSRlglsdreaqaqalqDRVDSLQRQVADSEVKAGTLQLTVERLNgALAKVEESEGALRDKVRGLTEALA 1736
Cdd:PRK02224   462 EGSPHVETIEEDR--------------ERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIA 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1737 QSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLrgevaDLELQRVEAEGQLQQLR 1816
Cdd:PRK02224   527 ERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL-----KERIESLERIRTLLAAI 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1817 EVLRQRQEGEAAALNTVQKLQDERRllqERLGSLQRALAQLEAEKREVERSALRLEKDRVAlrRTLDKVEREKLRSHEDT 1896
Cdd:PRK02224   602 ADAEDEIERLREKREALAELNDERR---ERLAEKRERKRELEAEFDEARIEEAREDKERAE--EYLEQVEEKLDELREER 676

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 2462515701 1897 VRLSAEKGRLDRTLTgaelELAEAQRQIQQLEAQVVVLEQSHSPAQ 1942
Cdd:PRK02224   677 DDLQAEIGAVENELE----ELEELRERREALENRVEALEALYDEAE 718
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 897-1023 2.24e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 46.23  E-value: 2.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  897 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKetltgeLAGLRQQIIATQEKASldkELMAQklVQA 976
Cdd:COG0542    397 EAAARVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFER------LAELRDELAELEEELE---ALKAR--WEA 465

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 2462515701  977 EREAQASLREQRAAHEEDLQRLQrEKEAAWRELEAERAQLQSQLQRE 1023
Cdd:COG0542    466 EKELIEEIQELKEELEQRYGKIP-ELEKELAELEEELAELAPLLREE 511
mukB PRK04863
chromosome partition protein MukB;
1599-1936 2.49e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 2.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1599 LDQVATLERSLQATESELRASQEKISKM-------KANETKLEGD-------------KRRLKEVLDASESRTVKLELQR 1658
Cdd:PRK04863   285 LEEALELRRELYTSRRQLAAEQYRLVEMarelaelNEAESDLEQDyqaasdhlnlvqtALRQQEKIERYQADLEELEERL 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1659 RSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVAD-------SEVKAGTLQLTVERLNGA----------LAKVEESE 1721
Cdd:PRK04863   365 EEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADyqqaldvQQTRAIQYQQAVQALERAkqlcglpdltADNAEDWL 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1722 GALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALT-----ACEHDRQVLQerlDAARQALSEARKQsSSLGEQVQTLRG 1796
Cdd:PRK04863   445 EEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiAGEVSRSEAW---DVARELLRRLREQ-RHLAEQLQQLRM 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1797 EVADLElQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQ----LEAEKREVERSALRLE 1872
Cdd:PRK04863   521 RLSELE-QRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARErrmaLRQQLEQLQARIQRLA 599

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462515701 1873 KDRVALRRTLDKVERekLRSH-----EDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQ 1936
Cdd:PRK04863   600 ARAPAWLAAQDALAR--LREQsgeefEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIERLSQ 666
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 355-1027 3.05e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.12  E-value: 3.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  355 AALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNK--DLTEKLEALES 432
Cdd:TIGR00618  225 EKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKaaPLAAHIKAVTQ 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  433 LRLQEQAAL-ETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASNGSLRGLSGQRTPsppRRSSPGRGRSPRRGP 511
Cdd:TIGR00618  305 IEQQAQRIHtELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATS---IREISCQQHTLTQHI 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  512 SPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREV 591
Cdd:TIGR00618  382 HTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHL 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  592 QRLRSAnellSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGArvrrELERSHRQLEQL 671
Cdd:TIGR00618  462 QESAQS----LKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDID----NPGPLTRRMQRG 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  672 EGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLA-- 749
Cdd:TIGR00618  534 EQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAce 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  750 QDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQeALEQQLPTLRHER 829
Cdd:TIGR00618  614 QHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQ-LALQKMQSEKEQL 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  830 SQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREkealakehagLAVQLVAAEREGRTLSEEATRLRLEKEAL 909
Cdd:TIGR00618  693 TYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSD----------LAAREDALNQSLKELMHQARTVLKARTEA 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  910 EGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRA 989
Cdd:TIGR00618  763 HFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSA 842

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 2462515701  990 AHEEdlQRLQREKEAAWRELEAERAQLQSQLQREQEEL 1027
Cdd:TIGR00618  843 TLGE--ITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1767-1996 3.07e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.08  E-value: 3.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1767 QERLDAARQALSEARKQSSSLGEQV-QTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAAlntvQKLQDERRLLQE 1845
Cdd:COG1196    185 EENLERLEDILGELERQLEPLERQAeKAERYRELKEELKELEAELLLLKLRELEAELEELEAEL----EELEAELEELEA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1846 RLGSLQralAQLEAEKREVERSALRLE---KDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQR 1922
Cdd:COG1196    261 ELAELE---AELEELRLELEELELELEeaqAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462515701 1923 QIQQLEAQVVVLEQSHSPAQLEVD----AQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVSTLKGQLQQELRR 1996
Cdd:COG1196    338 ELEELEEELEEAEEELEEAEAELAeaeeALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1093-1311 3.14e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1093 ERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDG 1172
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1173 LRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEE 1252
Cdd:COG4942    106 LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462515701 1253 ARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLA 1311
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 80-630 3.22e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 3.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   80 QEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELET--QEPRGLVRQSVELRRQLQEEQASYRR 157
Cdd:pfam15921  309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEarTERDQFSQESGNLDDQLQKLLADLHK 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  158 KLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLE--RSGELEQQRLRDTEHSQDLESALIR-----LEEEQQRSA 230
Cdd:pfam15921  389 REKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEvqRLEALLKAMKSECQGQMERQMAAIQgknesLEKVSSLTA 468

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  231 SLAQVNAMLREQLDQAGSANQALSEDIRKVTnDWTRCRKELEhreaawrREEESFNAYFSNEHSRLLLLWRQVVGFRRLV 310
Cdd:pfam15921  469 QLESTKEMLRKVVEELTAKKMTLESSERTVS-DLTASLQEKE-------RAIEATNAEITKLRSRVDLKLQELQHLKNEG 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  311 SEVK-MFTERDLLQLggELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQaLLQAQLEEQLRDKVLREKDLAQQQMQSD 389
Cdd:pfam15921  541 DHLRnVQTECEALKL--QMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQ-VEKAQLEKEINDRRLELQEFKILKDKKD 617

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  390 LDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE--TEDGEGLQQTLRDLAQAV-LSDSES 466
Cdd:pfam15921  618 AKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNslSEDYEVLKRNFRNKSEEMeTTTNKL 697

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  467 GVQLSGSERTADASNGSLRGLSGqrtpspprrsspgrgrsprrgpspacSDSSTLALIHSAlhkrQLQVQDMRGRYEASQ 546
Cdd:pfam15921  698 KMQLKSAQSELEQTRNTLKSMEG--------------------------SDGHAMKVAMGM----QKQITAKRGQIDALQ 747

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  547 DLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNL-----AHSLQVAQQQAEE 621
Cdd:pfam15921  748 SKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMevaldKASLQFAECQDII 827


                   ....*....
gi 2462515701  622 LRQEREKLQ 630
Cdd:pfam15921  828 QRQEQESVR 836
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 688-1031 3.80e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 45.82  E-value: 3.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  688 ALSRATLQRDMLQAE------KAEVAEALTKAEAGRVELELSMTKLRAEEASLqDSLSKLSA------LNESLAQDKLDL 755
Cdd:PRK10929    22 APDEKQITQELEQAKaaktpaQAEIVEALQSALNWLEERKGSLERAKQYQQVI-DNFPKLSAelrqqlNNERDEPRSVPP 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  756 NRLVAQLEEE----KSALQGRQRQAEQEATVAREEQERLEELRLEQEVAR----------QGLEGSLRVAEQAQEALEQQ 821
Cdd:PRK10929   101 NMSTDALEQEilqvSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARrqlneierrlQTLGTPNTPLAQAQLTALQA 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  822 LPTLRheRSQLQE-QLAQLS---RQ-LSGREQELEQARRE--------------AQRQVEAlERAAREKEALAKEHAGLA 882
Cdd:PRK10929   181 ESAAL--KALVDElELAQLSannRQeLARLRSELAKKRSQqldaylqalrnqlnSQRQREA-ERALESTELLAEQSGDLP 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  883 VQLVAAEREGRTLSEEatrlrLEKEALEGSLF-EVQRQLAQ--LEARREQLEAEGQALLLAKETLTGElaGLRQQIIATQ 959
Cdd:PRK10929   258 KSIVAQFKINRELSQA-----LNQQAQRMDLIaSQQRQAASqtLQVRQALNTLREQSQWLGVSNALGE--ALRAQVARLP 330

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462515701  960 EKAsldkelmaqKLVQAEREaQASLREQRAAHEEDLQRLQRE---KEAAWRELEAERAQLQSQLQREQEELLARL 1031
Cdd:PRK10929   331 EMP---------KPQQLDTE-MAQLRVQRLRYEDLLNKQPQLrqiRQADGQPLTAEQNRILDAQLRTQRELLNSL 395
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 959-1298 4.18e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.50  E-value: 4.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  959 QEKASLDKEL-MAQKLVQAEREAQASLREQRAAHEEdlqrlqREKEAAWRELEAERAQLQSQlQREQEELlarleaekee 1037
Cdd:pfam17380  303 QEKEEKAREVeRRRKLEEAEKARQAEMDRQAAIYAE------QERMAMERERELERIRQEER-KRELERI---------- 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1038 lseeiaalqqerdeglllaeseKQQALSLKESEKTALSEklmgtrhslatisLEMERQKRDAQSRQEQDRSTVNALTSEL 1117
Cdd:pfam17380  366 ----------------------RQEEIAMEISRMRELER-------------LQMERQQKNERVRQELEAARKVKILEEE 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1118 RdlrAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLR-RELLEAQRKLRESQEGREVQRQ 1196
Cdd:pfam17380  411 R---QRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERlRQQEEERKRKKLELEKEKRDRK 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1197 EAGELRRSLGEgaKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAvgKEAGELRTGLQEV----- 1271
Cdd:pfam17380  488 RAEEQRRKILE--KELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQ--QEMEERRRIQEQMrkate 563

                          330       340
                   ....*....|....*....|....*..
gi 2462515701 1272 ERSRLEARRELQELRRQMKmlDSENTR 1298
Cdd:pfam17380  564 ERSRLEAMEREREMMRQIV--ESEKAR 588
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 74-874 4.24e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 4.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   74 ASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQ--EPRGLVRQSVELRRQLQEE 151
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEiaSLERSIAEKERELEDAEER 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  152 QA-------SYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGEL---------EQQRLRDTEHS-QD 214
Cdd:TIGR02169  324 LAkleaeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrdelkdYREKLEKLKREiNE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  215 LESALIRLEEE-QQRSASLAQVNAML---REQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFS 290
Cdd:TIGR02169  404 LKRELDRLQEElQRLSEELADLNAAIagiEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEK 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  291 NEHSRLLLL---------WRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAgLGLSTGLRLaesrAEAALEKQA 361
Cdd:TIGR02169  484 ELSKLQRELaeaeaqaraSEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATA-IEVAAGNRL----NNVVVEDDA 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  362 LLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVkrlekqnlekdqvnkDLTEKLEALESLrlqeqaal 441
Cdd:TIGR02169  559 VAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAV---------------DLVEFDPKYEPA-------- 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  442 etedgegLQQTLRDlaQAVLSDSESGVQLSGSERTAdASNGSLRGLSGQRTpspprrsspGRGRSPRRGPSPACSDSStl 521
Cdd:TIGR02169  616 -------FKYVFGD--TLVVEDIEAARRLMGKYRMV-TLEGELFEKSGAMT---------GGSRAPRGGILFSRSEPA-- 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  522 alihsalhkrqlQVQDMRGRyeasqdlLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELL 601
Cdd:TIGR02169  675 ------------ELQRLRER-------LEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  602 SREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRreLERSHRQLEQLEGKRSVLAKE 681
Cdd:TIGR02169  736 KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEIQAELSKLEEEVSRIEAR 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  682 LVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQ 761
Cdd:TIGR02169  814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  762 LEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRvAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 841
Cdd:TIGR02169  894 LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKG-EDEEIPEEELSLEDVQAELQRVEEEIRALEP 972

                          810       820       830
                   ....*....|....*....|....*....|...
gi 2462515701  842 QLSGREQELEQARREAQRQVEALERAAREKEAL 874
Cdd:TIGR02169  973 VNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1644-1882 4.54e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1644 LDASESRTVKLELQRRSLEG--ELQRSRLGLSDREAQAQAL---------QDRVDSLQRQVADsevkagtLQLTVERLNG 1712
Cdd:COG4913    237 LERAHEALEDAREQIELLEPirELAERYAAARERLAELEYLraalrlwfaQRRLELLEAELEE-------LRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1713 ALAKVEESEGALRDKVRGLTEALAQSSAslnstrdknlhlqKALTACEHDRQVLQERLDAARQALSEARKQssslgeqvq 1792
Cdd:COG4913    310 ELERLEARLDALREELDELEAQIRGNGG-------------DRLEQLEREIERLERELEERERRRARLEAL--------- 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1793 tlrgeVADLELQRVEAEGQLQQLREVLRQRQEGEAAALntvQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLE 1872
Cdd:COG4913    368 -----LAALGLPLPASAEEFAALRAEAAALLEALEEEL---EALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIP 439

                          250
                   ....*....|
gi 2462515701 1873 KDRVALRRTL 1882
Cdd:COG4913    440 ARLLALRDAL 449
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 527-779 4.94e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 4.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  527 ALHKRQLQVQDMRGRYEASQdlLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKS 606
Cdd:TIGR02169  773 DLHKLEEALNDLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK 850

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  607 NLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEqedavqdgarvRRELErshRQLEQLEGKRSVLAKELVEVR 686
Cdd:TIGR02169  851 SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE-----------RDELE---AQLRELERKIEELEAQIEKKR 916

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  687 EALSRATLQRDMLQAEKAEVaEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALN-------ESLAQDKLDLNRLV 759
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEI-EDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNmlaiqeyEEVLKRLDELKEKR 995

                          250       260
                   ....*....|....*....|
gi 2462515701  760 AQLEEEKSALQGRQRQAEQE 779
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKK 1015
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1772-1945 4.97e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 45.23  E-value: 4.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1772 AARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVL---RQRQEGEAAALNTVQKLQDERRLLQERLG 1848
Cdd:COG2433    403 HEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELseaRSEERREIRKDREISRLDREIERLERELE 482

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1849 SLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEaqrQIQQLE 1928
Cdd:COG2433    483 EERERIEELKRKLERLKELWKLEHSGELVPVKVVEKFTKEAIRRLEEEYGLKEGDVVYLRDASGAGRSTAE---LLAEAG 559

                          170
                   ....*....|....*..
gi 2462515701 1929 AQVVVLEQSHSPAQLEV 1945
Cdd:COG2433    560 PRAVIVPGELSEAADEV 576
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1511-1850 5.05e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.89  E-value: 5.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1511 LREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRR 1590
Cdd:pfam07888   47 LQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAA 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1591 SERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESrtvklelQRRSLEGELQRSRL 1670
Cdd:pfam07888  127 HEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEE-------ELRSLSKEFQELRN 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1671 GLSDREAQAQALQDRVDSL-------QRQVADSEVKAGTLQLTVERLNGALAKVE------ESEGALRDKVRG-LTEALA 1736
Cdd:pfam07888  200 SLAQRDTQVLQLQDTITTLtqklttaHRKEAENEALLEELRSLQERLNASERKVEglgeelSSMAAQRDRTQAeLHQARL 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1737 QSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLE-----------LQR 1805
Cdd:pfam07888  280 QAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEvelgrekdcnrVQL 359

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 2462515701 1806 VEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSL 1850
Cdd:pfam07888  360 SESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETV 404
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1514-1986 5.93e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 5.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1514 FLQELRSAQRERDELRTQtsalNRQLAEMEAERDSATSRARQLQKAVAESEEARRsvdgrlsgvQAELALQEESVRRSER 1593
Cdd:COG4717     69 NLKELKELEEELKEAEEK----EEEYAELQEELEELEEELEELEAELEELREELE---------KLEKLLQLLPLYQELE 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1594 ERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVK-LELQRRSLEGELQRSRLGL 1672
Cdd:COG4717    136 ALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQdLAEELEELQQRLAELEEEL 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1673 SDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLnstrdknlhL 1752
Cdd:COG4717    216 EEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL---------L 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1753 QKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALnt 1832
Cdd:COG4717    287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ-- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1833 VQKLQDERRLLQERLGSLQRALAQLEAEKREvERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTG 1912
Cdd:COG4717    365 LEELEQEIAALLAEAGVEDEEELRAALEQAE-EYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEE 443

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462515701 1913 AELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVSTL 1986
Cdd:COG4717    444 LEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPV 517
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
527-954 5.98e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 5.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  527 ALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANEllsREKS 606
Cdd:COG4717    119 EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQ 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  607 NLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDgarvrrelershRQLEQLEGKRSVLAKELVEVR 686
Cdd:COG4717    196 DLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE------------ERLKEARLLLLIAAALLALLG 263

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  687 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 766
Cdd:COG4717    264 LGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELL 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  767 SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQlptlrhersQLQEQLAQLSRQLSGR 846
Cdd:COG4717    344 DRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQ---------ELKEELEELEEQLEEL 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  847 EQELEQarreaqrqvealERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALE--GSLFEVQRQLAQLE 924
Cdd:COG4717    415 LGELEE------------LLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEedGELAELLQELEELK 482

                          410       420       430
                   ....*....|....*....|....*....|
gi 2462515701  925 ARREQLEAEGQALLLAKETLTGELAGLRQQ 954
Cdd:COG4717    483 AELRELAEEWAALKLALELLEEAREEYREE 512
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
528-1010 6.49e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 6.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  528 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRdKTDGAMQAHEDAQREVQRLRSANELLSREKSN 607
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  608 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDA--VQDGARVRRELER-----SHRQLEQLEGKRSVLAK 680
Cdd:PRK03918   319 LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHelYEEAKAKKEELERlkkrlTGLTPEKLEKELEELEK 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  681 ELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEE---------ASLQDSLSKLSALNESLAQD 751
Cdd:PRK03918   399 AKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkelleeytAELKRIEKELKEIEEKERKL 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  752 KLDLNRLVAQLEEEKSALQGRQ-----RQAEQEATVAREEQERLEELRLEQEVAR-QGLEGSLRVAE---QAQEALEQQL 822
Cdd:PRK03918   479 RKELRELEKVLKKESELIKLKElaeqlKELEEKLKKYNLEELEKKAEEYEKLKEKlIKLKGEIKSLKkelEKLEELKKKL 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  823 PTLRHERSQLQEQLAQLSRQLsgreqeleqaRREAQRQVEALERAAREKEALAKEHaglaVQLVAAEREgrtLSEEATRL 902
Cdd:PRK03918   559 AELEKKLDELEEELAELLKEL----------EELGFESVEELEERLKELEPFYNEY----LELKDAEKE---LEREEKEL 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  903 RLEKEALEGSLFEVQRQLAQLEARREQLEAegqallLAKETLTGELAGLRqqiiatQEKASLDKELMAqklVQAEREAQA 982
Cdd:PRK03918   622 KKLEEELDKAFEELAETEKRLEELRKELEE------LEKKYSEEEYEELR------EEYLELSRELAG---LRAELEELE 686

                          490       500
                   ....*....|....*....|....*...
gi 2462515701  983 SLREQRAAHEEDLQRLQREKEAAWRELE 1010
Cdd:PRK03918   687 KRREEIKKTLEKLKEELEEREKAKKELE 714
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1068-1430 7.56e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 7.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1068 ESEKTALSEKLMGTRHSLATISLEMER---QKRDAQSRQE-------------QDRSTVNALTSELRDLRAQREEAAAAH 1131
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERyeeQREQARETRDeadevleeheerrEELETLEAEIEDLRETIAETEREREEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1132 AQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLREsqegrevQRQEAGELRRSLGEGAKE 1211
Cdd:PRK02224   278 AEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEE-------CRVAAQAHNEEAESLRED 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1212 REALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKM 1291
Cdd:PRK02224   351 ADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1292 LDSENTRLGRELAELQGRLA------LGERAEKESRRETLG-LRQRLLKGEASLEVMRQELQVAQRKLQEQEgEFRTRER 1364
Cdd:PRK02224   431 LEATLRTARERVEEAEALLEagkcpeCGQPVEGSPHVETIEeDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAED 509

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462515701 1365 RLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELG-LRLSAAEGRAQGLEAELARVEVQRRAAE 1430
Cdd:PRK02224   510 RIERLEERREDLEELIAERRETIEEKRERAEELRERAAeLEAEAEEKREAAAEAEEEAEEAREEVAE 576
mukB PRK04863
chromosome partition protein MukB;
642-1030 7.89e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 7.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  642 RLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEA-GRVEL 720
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKiERYQA 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  721 ELSMTKLRAEEAS--LQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATvAREEQERLEELRLEQE 798
Cdd:PRK04863   356 DLEELEERLEEQNevVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQ-AVQALERAKQLCGLPD 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  799 VARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQ------EQLAQLSRQLSGreqelEQARREAQRQVEALERAAREKE 872
Cdd:PRK04863   435 LTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQaahsqfEQAYQLVRKIAG-----EVSRSEAWDVARELLRRLREQR 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  873 ALAKEHAGLAVQLVAAEREgrtLSEEATRLRLEKEALEGSLFEVQRQlAQLEARREQLEAEGQALLLAKETLTGELAGLR 952
Cdd:PRK04863   510 HLAEQLQQLRMRLSELEQR---LRQQQRAERLLAEFCKRLGKNLDDE-DELEQLQEELEARLESLSESVSEARERRMALR 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  953 QQIiatQEKASLDKELMAQKLV-QAEREAQASLREQRAAHEEDLQRL------QREKEAAWRELEAERAQLQSQLQREQE 1025
Cdd:PRK04863   586 QQL---EQLQARIQRLAARAPAwLAAQDALARLREQSGEEFEDSQDVteymqqLLERERELTVERDELAARKQALDEEIE 662


                   ....*
gi 2462515701 1026 ELLAR 1030
Cdd:PRK04863   663 RLSQP 667
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 544-918 9.06e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 9.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  544 ASQDLLGTLRKQLSDSESERRALEEQlqrlrdktdgaMQAHEDAQRevqrlrsanelLSREKSNLAHSLQVAQQQAEELR 623
Cdd:NF012221  1539 ESSQQADAVSKHAKQDDAAQNALADK-----------ERAEADRQR-----------LEQEKQQQLAAISGSQSQLESTD 1596

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  624 QereklQAAQEELRRQRDRLEEEQEDavqdgarVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRdmlqaek 703
Cdd:NF012221  1597 Q-----NALETNGQAQRDAILEESRA-------VTKELTTLAQGLDALDSQATYAGESGDQWRNPFAGGLLDR------- 1657

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  704 aeVAEAL--TKAEAGrVELELSMTKLRAEEASLQDSLSKLSAlneslAQDKLDLNRLVAQLEEEKSALQGRQRQaeQEAT 781
Cdd:NF012221  1658 --VQEQLddAKKISG-KQLADAKQRHVDNQQKVKDAVAKSEA-----GVAQGEQNQANAEQDIDDAKADAEKRK--DDAL 1727

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  782 VAREEqerleelrleqevARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQlAQLSRQLSGREQEleqaRREAQRQV 861
Cdd:NF012221  1728 AKQNE-------------AQQAESDANAAANDAQSRGEQDASAAENKANQAQAD-AKGAKQDESDKPN----RQGAAGSG 1789

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462515701  862 EALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEatrlrlEKEALEGSLFEVQR 918
Cdd:NF012221  1790 LSGKAYSVEGVAEPGSHINPDSPAAADGRFSEGLTEQ------EQEALEGATNAVNR 1840
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 830-1072 9.29e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.15  E-value: 9.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  830 SQLQE----QLAQLSRQLSGreQELEQARREAQRQVEALE--RAAREKEALAKEhaglavqlVAAEREGRTLSEEATRLR 903
Cdd:PRK05771    23 EALHElgvvHIEDLKEELSN--ERLRKLRSLLTKLSEALDklRSYLPKLNPLRE--------EKKKVSVKSLEELIKDVE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  904 LEKEALEGSLFEVQRQLAQLEARREQLEAEGQAL------------LLAKETLTGELAGL------RQQIIATQEKASLD 965
Cdd:PRK05771    93 EELEKIEKEIKELEEEISELENEIKELEQEIERLepwgnfdldlslLLGFKYVSVFVGTVpedkleELKLESDVENVEYI 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  966 KELMAQK--LVQAEREAQASLREQRAAHEEDLQRLQREKEAAwRELEAERAQLqSQLQREQEELLARLEAEKEELSEEIA 1043
Cdd:PRK05771   173 STDKGYVyvVVVVLKELSDEVEEELKKLGFERLELEEEGTPS-ELIREIKEEL-EEIEKERESLLEELKELAKKYLEELL 250

                          250       260       270
                   ....*....|....*....|....*....|
gi 2462515701 1044 ALqqerdEGLLLAESEKQQALS-LKESEKT 1072
Cdd:PRK05771   251 AL-----YEYLEIELERAEALSkFLKTDKT 275
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
541-1071 9.58e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.28  E-value: 9.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  541 RYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAmqahEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAE 620
Cdd:PRK03918   187 RTENIEELIKEKEKELEEVLREINEISSELPELREELEKL----EKEVKELEELKEEIEELEKELESLEGSKRKLEEKIR 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  621 ELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGA--RVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDM 698
Cdd:PRK03918   263 ELEERIEELKKEIEELEEKVKELKELKEKAEEYIKlsEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  699 LQAEKAEVAEALTKAEAGRVELElsmtKLRAEEASLQDSLSKLSALN-ESLAQDKLDLNRLVAQLEEEKSALQGRQRQAE 777
Cdd:PRK03918   343 LKKKLKELEKRLEELEERHELYE----EAKAKKEELERLKKRLTGLTpEKLEKELEELEKAKEEIEEEISKITARIGELK 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  778 QEATVAREEQERLEELRLEQEVARQGLEGSLRvaEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARR-- 855
Cdd:PRK03918   419 KEIKELKKAIEELKKAKGKCPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEli 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  856 ---EAQRQVEALERA-----AREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLrlekEALEGSLFEVQRQLAQLEARR 927
Cdd:PRK03918   497 klkELAEQLKELEEKlkkynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDELEEEL 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  928 EQLEAEGQALLLAK-ETLTGELAGLRQQIIATQEKASLDKELmaqklvQAEREAQASLREQRAAHEEDLQRLQREKEAAW 1006
Cdd:PRK03918   573 AELLKELEELGFESvEELEERLKELEPFYNEYLELKDAEKEL------EREEKELKKLEEELDKAFEELAETEKRLEELR 646

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462515701 1007 RELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEK 1071
Cdd:PRK03918   647 KELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKK 711
PRK11281 PRK11281
mechanosensitive channel MscK;
17-257 1.01e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   17 TVIQTLESS--VLCQEKGLGARDLAQDAQITSLPALIREIVTR--NLSQPESPVL---LPATEMASLLSLQEE--NQL-- 85
Cdd:PRK11281    60 LVQQDLEQTlaLLDKIDRQKEETEQLKQQLAQAPAKLRQAQAEleALKDDNDEETretLSTLSLRQLESRLAQtlDQLqn 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   86 LQQELSRVEDLL--AQSRAERDELAIKYNavSERLEQALRLEPGELETQEPrglvrQSVELRRQLQEEQA------SYRR 157
Cdd:PRK11281   140 AQNDLAEYNSQLvsLQTQPERAQAALYAN--SQRLQQIRNLLKGGKVGGKA-----LRPSQRVLLQAEQAllnaqnDLQR 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  158 KLQA--------YQ-------EGQQRQAQLVQRLQGKILQykKRCSELEQQLLE-RSGELEQQRLRDTEHSQDLESALI- 220
Cdd:PRK11281   213 KSLEgntqlqdlLQkqrdyltARIQRLEHQLQLLQEAINS--KRLTLSEKTVQEaQSQDEAARIQANPLVAQELEINLQl 290

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 2462515701  221 --RLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDI 257
Cdd:PRK11281   291 sqRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQI 329
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
727-1044 1.15e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  727 LRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQgleg 806
Cdd:COG4372     33 LRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE---- 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  807 SLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHA--GLAVQ 884
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAeqALDEL 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  885 LVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASL 964
Cdd:COG4372    189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  965 DKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAA 1044
Cdd:COG4372    269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLV 348
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 547-954 1.26e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.17  E-value: 1.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  547 DLLGTLRKQLSDSESERRALEEQLQRLRDKtdgaMQAHEDAQREV-QRLRSANELLSReksnlahsLQVAQQQAEELRQE 625
Cdd:COG3096    285 ERALELRRELFGARRQLAEEQYRLVEMARE----LEELSARESDLeQDYQAASDHLNL--------VQTALRQQEKIERY 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  626 REKLQAAQEELRRQRDRLEEEQEdavqdgarvrrELERSHRQLEQLEGKRSVLAKELVEVREAL----SRATLQRDMLQA 701
Cdd:COG3096    353 QEDLEELTERLEEQEEVVEEAAE-----------QLAEAEARLEAAEEEVDSLKSQLADYQQALdvqqTRAIQYQQAVQA 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  702 -EKAEVAEALTKAEAGRVELELSMTKLRAEEA-----SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ-- 773
Cdd:COG3096    422 lEKARALCGLPDLTPENAEDYLAAFRAKEQQAteevlELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAWQTAREll 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  774 -------RQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQ--AQEALEQQLPTLRHERSQLQEQLAQLSRQLS 844
Cdd:COG3096    502 rryrsqqALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQldAAEELEELLAELEAQLEELEEQAAEAVEQRS 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  845 GREQELEQ--ARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRtlseeATRLRLEKEAlegslfEVQRQlaQ 922
Cdd:COG3096    582 ELRQQLEQlrARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAM-----QQLLEREREA------TVERD--E 648

                          410       420       430
                   ....*....|....*....|....*....|..
gi 2462515701  923 LEARREQLEAEGQALLLAKETLTGELAGLRQQ 954
Cdd:COG3096    649 LAARKQALESQIERLSQPGGAEDPRLLALAER 680
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 816-1290 1.35e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.86  E-value: 1.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  816 EALEQQLPTLRHERSQLQEQLAQLSRQLSGRE------QELEQARREAQRQVEALERA----AREKEALAKEHAGLAVQL 885
Cdd:TIGR04523  169 EELENELNLLEKEKLNIQKNIDKIKNKLLKLElllsnlKKKIQKNKSLESQISELKKQnnqlKDNIEKKQQEINEKTTEI 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  886 VAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKE-----TLTGELAGLRQQIIATQE 960
Cdd:TIGR04523  249 SNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQN 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  961 KASLDKELMAQ---KLVQAEREAQ------ASLREQRAAHEEDLQRLQREKEAAWRE---LEAERAQLQSQLQrEQEELL 1028
Cdd:TIGR04523  329 QISQNNKIISQlneQISQLKKELTnsesenSEKQRELEEKQNEIEKLKKENQSYKQEiknLESQINDLESKIQ-NQEKLN 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1029 ARLEAEKEELSEEIAALQQERDEglLLAESEKQQA----LSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQE 1104
Cdd:TIGR04523  408 QQKDEQIKKLQQEKELLEKEIER--LKETIIKNNSeikdLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1105 QDRSTVNALTSELRDLRAQreeaaaahaqeVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL 1184
Cdd:TIGR04523  486 QKQKELKSKEKELKKLNEE-----------KKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFEL 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1185 RESQEGREVQrqeagELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGEL 1264
Cdd:TIGR04523  555 KKENLEKEID-----EKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKL 629

                          490       500
                   ....*....|....*....|....*.
gi 2462515701 1265 RTGLQEVERSRLEARRELQELRRQMK 1290
Cdd:TIGR04523  630 SSIIKNIKSKKNKLKQEVKQIKETIK 655
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 566-928 1.39e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 43.35  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  566 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEE 645
Cdd:pfam07888   36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  646 EQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMT 725
Cdd:pfam07888  116 EKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  726 KLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLE 805
Cdd:pfam07888  196 ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELH 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  806 GSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEA----LAKEHAGL 881
Cdd:pfam07888  276 QARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKleveLGREKDCN 355

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 2462515701  882 AVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 928
Cdd:pfam07888  356 RVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1715-1998 1.44e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1715 AKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTL 1794
Cdd:COG4372      6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1795 RGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKD 1874
Cdd:COG4372     86 NEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEE 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1875 RVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLEL 1954
Cdd:COG4372    166 LAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELE 245

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 2462515701 1955 QQEVERLRSAQAQTERTLEARERAHRQRVSTLKGQLQQELRRSS 1998
Cdd:COG4372    246 EDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALE 289
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 855-1031 1.55e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  855 REAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEG 934
Cdd:COG1579      3 PEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQL 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  935 QALLLAKE--TLTGELAGLRQQIIATQEKAsldKELMAQklVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAE 1012
Cdd:COG1579     83 GNVRNNKEyeALQKEIESLKRRISDLEDEI---LELMER--IEELEEELAELEAELAELEAELEEKKAELDEELAELEAE 157

                          170
                   ....*....|....*....
gi 2462515701 1013 RAQLQSQLQREQEELLARL 1031
Cdd:COG1579    158 LEELEAEREELAAKIPPEL 176
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1135-1351 1.72e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1135 VRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELrrslgegakerea 1214
Cdd:COG4942     43 LAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL------------- 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1215 lrrsneeLRSAVKKAESERISLKLANEDKEQ---KLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKM 1291
Cdd:COG4942    110 -------LRALYRLGRQPPLALLLSPEDFLDavrRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1292 LDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRK 1351
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
522-849 1.80e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.97  E-value: 1.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  522 ALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELL 601
Cdd:COG4372     27 AALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESL 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  602 SREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEgkrsvlAKE 681
Cdd:COG4372    107 QEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALS------EAE 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  682 LVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQ 761
Cdd:COG4372    181 AEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEI 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  762 LEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 841
Cdd:COG4372    261 EELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELA 340


                   ....*...
gi 2462515701  842 QLSGREQE 849
Cdd:COG4372    341 DLLQLLLV 348
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 560-1285 1.85e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.63  E-value: 1.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  560 ESERRALEEQLQRLRDKtdgamqaHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQ 639
Cdd:pfam01576    4 EEEMQAKEEELQKVKER-------QQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEI 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  640 RDRLEeeqedavqdgARVRRELERShrqlEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVE 719
Cdd:pfam01576   77 LHELE----------SRLEEEEERS----QQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILL 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  720 LELSMTKLRAEEASLQDSLSKLSAlneslaqdkldlnrlvAQLEEEKSALQGRQRQAEQEATVAReeqerleelrleqev 799
Cdd:pfam01576  143 LEDQNSKLSKERKLLEERISEFTS----------------NLAEEEEKAKSLSKLKNKHEAMISD--------------- 191

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  800 arqgLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHA 879
Cdd:pfam01576  192 ----LEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIR 267

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  880 GLAVQL------VAAEREGRTLSEEATR-LRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALllaKETLTGELAGLR 952
Cdd:pfam01576  268 ELEAQIselqedLESERAARNKAEKQRRdLGEELEALKTELEDTLDTTAAQQELRSKREQEVTEL---KKALEEETRSHE 344

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  953 QQIIATQEKASLDKELMAQKLVQAEReAQASLREQRAAHEEDLQRLQREK---EAAWRELEAERAQLQSQLQreqeELLA 1029
Cdd:pfam01576  345 AQLQEMRQKHTQALEELTEQLEQAKR-NKANLEKAKQALESENAELQAELrtlQQAKQDSEHKRKKLEGQLQ----ELQA 419

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1030 RLEAEKEELSEEiaalqqerdeglllaeSEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRST 1109
Cdd:pfam01576  420 RLSESERQRAEL----------------AEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQ 483

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1110 VNALTSELRDLRAQREEAAAAHAQEV---RRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE 1186
Cdd:pfam01576  484 KLNLSTRLRQLEDERNSLQEQLEEEEeakRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEE 563

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1187 SQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKK-----AESERISLKLANE-DKEQKLALLEEART-AVGK 1259
Cdd:pfam01576  564 KAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKfdqmlAEEKAISARYAEErDRAEAEAREKETRAlSLAR 643

                          730       740
                   ....*....|....*....|....*.
gi 2462515701 1260 EAGELRTGLQEVERSRLEARRELQEL 1285
Cdd:pfam01576  644 ALEEALEAKEELERTNKQLRAEMEDL 669
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 580-743 1.92e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  580 AMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVR- 658
Cdd:COG1579      1 AMPEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEe 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  659 --------RELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAgrvELELSMTKLRAE 730
Cdd:COG1579     81 qlgnvrnnKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKA---ELDEELAELEAE 157

                          170
                   ....*....|...
gi 2462515701  731 EASLQDSLSKLSA 743
Cdd:COG1579    158 LEELEAEREELAA 170
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 583-1300 1.97e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 1.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  583 AHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQedavqdgaRVRRELE 662
Cdd:TIGR00618  192 LHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL--------KKQQLLK 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  663 RSHRQLEQLEGkrsvLAKELVEVREALSRATlQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLraeeaslqdslSKLS 742
Cdd:TIGR00618  264 QLRARIEELRA----QEAVLEETQERINRAR-KAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSR-----------AKLL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  743 ALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEelrleqevarqgLEGSLRVAEQAQEALEQQL 822
Cdd:TIGR00618  328 MKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHT------------LTQHIHTLQQQKTTLTQKL 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  823 PTLRHERSQLQEQLAQLSRQLSgREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRL 902
Cdd:TIGR00618  396 QSLCKELDILQREQATIDTRTS-AFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQ 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  903 RLEKEAL-----------EGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELmaq 971
Cdd:TIGR00618  475 LQTKEQIhlqetrkkavvLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQL--- 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  972 klvQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDE 1051
Cdd:TIGR00618  552 ---TSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQ 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1052 GLLLAESEKQQALSLKESEKTALSEKLM--GTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDL---RAQREE 1126
Cdd:TIGR00618  629 DVRLHLQQCSQELALKLTALHALQLTLTqeRVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLaqcQTLLRE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1127 AAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLG 1206
Cdd:TIGR00618  709 LETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQ 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1207 EGAKEREALRRSNEELRSAVK-KAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVErsrlEARRELQEL 1285
Cdd:TIGR00618  789 FFNRLREEDTHLLKTLEAEIGqEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYE----ECSKQLAQL 864

                          730
                   ....*....|....*
gi 2462515701 1286 RRQMKMLDSENTRLG 1300
Cdd:TIGR00618  865 TQEQAKIIQLSDKLN 879
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
585-920 1.98e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.58  E-value: 1.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  585 EDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERS 664
Cdd:COG4372     34 RKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEEL 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  665 HRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSAL 744
Cdd:COG4372    114 QEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEAN 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  745 NESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPT 824
Cdd:COG4372    194 RNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDT 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  825 LRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRL 904
Cdd:COG4372    274 EEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDN 353

                          330
                   ....*....|....*.
gi 2462515701  905 EKEALEGSLFEVQRQL 920
Cdd:COG4372    354 DVLELLSKGAEAGVAD 369
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 826-1299 2.66e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 42.81  E-value: 2.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  826 RHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAERE-GRTLSEEATRLRL 904
Cdd:pfam05557    1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEaEEALREQAELNRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  905 EKEALEGslfevqrqLAQLEARREQLEAEGQALLLAketLTGELAGLRQQI-IATQEKASLDKELMAQKLVQAEREAQAS 983
Cdd:pfam05557   81 KKKYLEA--------LNKKLNEKESQLADAREVISC---LKNELSELRRQIqRAELELQSTNSELEELQERLDLLKAKAS 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  984 LREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS---QLQREQEEL--LARLEAEKEELSEEIAALQQERDEGLLLAES 1058
Cdd:pfam05557  150 EAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQdseIVKNSKSELarIPELEKELERLREHNKHLNENIENKLLLKEE 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1059 ekqqalslKESEKTALsEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTS---------ELRDLRAQREEAAA 1129
Cdd:pfam05557  230 --------VEDLKRKL-EREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSpedlsrrieQLQQREIVLKEENS 300

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1130 AHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQ------RKLRESQEGREVQRQEAGELRR 1203
Cdd:pfam05557  301 SLTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTkerdgyRAILESYDKELTMSNYSPQLLE 380

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1204 SLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEeaRTAVGKEAGELRTGLQEVERSRLEARRELQ 1283
Cdd:pfam05557  381 RIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALR--QQESLADPSYSKEEVDSLRRKLETLELERQ 458

                          490
                   ....*....|....*.
gi 2462515701 1284 ELRRQMKMLDSENTRL 1299
Cdd:pfam05557  459 RLREQKNELEMELERR 474
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 18-271 2.98e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.73  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   18 VIQTLESSVLCQEKGLGARDLAQDAQ--ITSLPALIREIVTRNLSQPESPVLLPATEMASLLS---LQEENQLL------ 86
Cdd:PRK10929    46 IVEALQSALNWLEERKGSLERAKQYQqvIDNFPKLSAELRQQLNNERDEPRSVPPNMSTDALEqeiLQVSSQLLeksrqa 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701   87 QQELSR---VEDLLAQSRAERDELAIKYNAVSERLeQALrlepgeletqePRGLVRQSVELRRQLQEEQASYRRKLQAYQ 163
Cdd:PRK10929   126 QQEQDRareISDSLSQLPQQQTEARRQLNEIERRL-QTL-----------GTPNTPLAQAQLTALQAESAALKALVDELE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  164 EGQ--QRQAQLVQRLQGKIlqYKKRCSELEQQLLERSGELEQQRLRDTehsqdlESALIRLEEEQQRSASLA-------Q 234
Cdd:PRK10929   194 LAQlsANNRQELARLRSEL--AKKRSQQLDAYLQALRNQLNSQRQREA------ERALESTELLAEQSGDLPksivaqfK 265

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 2462515701  235 VNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKEL 271
Cdd:PRK10929   266 INRELSQALNQQAQRMDLIASQQRQAASQTLQVRQAL 302
PTZ00121 PTZ00121
MAEBL; Provisional
 527-741 3.12e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 3.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  527 ALHKRQLQVQDMRGRYEASQDLLGTLRKQlsDSESERRALEEQL--QRLRDKTDGAMQAHEDAQREVQRLRSANELLSRE 604
Cdd:PTZ00121  1579 ALRKAEEAKKAEEARIEEVMKLYEEEKKM--KAEEAKKAEEAKIkaEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE 1656

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  605 KSNLAHSLQVAQQQAEELRQErEKLQAAQEELRRQRDRLEEEQEDAvQDGARVRRELERSHRQLEQL---EGKRSVLAKE 681
Cdd:PTZ00121  1657 EENKIKAAEEAKKAEEDKKKA-EEAKKAEEDEKKAAEALKKEAEEA-KKAEELKKKEAEEKKKAEELkkaEEENKIKAEE 1734

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  682 LVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKL 741
Cdd:PTZ00121  1735 AKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRM 1794
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
1760-1868 3.68e-03

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 41.76  E-value: 3.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1760 EHDRQVLQERLDAARQALSEARKQSS--SLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEgeaaalnTVQKLQ 1837
Cdd:COG3524    183 EEEVERAEERLRDAREALLAFRNRNGilDPEATAEALLQLIATLEGQLAELEAELAALRSYLSPNSP-------QVRQLR 255

                           90       100       110
                   ....*....|....*....|....*....|.
gi 2462515701 1838 DERRLLQERLGSLQRALAQLEAEKREVERSA 1868
Cdd:COG3524    256 RRIAALEKQIAAERARLTGASGGDSLASLLA 286
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1209-1443 3.70e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1209 AKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQ 1288
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1289 MKMLDSENTRLGR-----------ELAELQGRLALGERAEKESRRETLGLRQRLlkgeASLEVMRQELQVAQRKLQEQEG 1357
Cdd:COG4942    106 LAELLRALYRLGRqpplalllspeDFLDAVRRLQYLKYLAPARREQAEELRADL----AELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1358 EFRTRERRLlgsleEARGTEKQQLdharglelkLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLR 1437
Cdd:COG4942    182 ELEEERAAL-----EALKAERQKL---------LARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247


                   ....*.
gi 2462515701 1438 SALRRG 1443
Cdd:COG4942    248 FAALKG 253
mukB PRK04863
chromosome partition protein MukB;
1507-2000 4.58e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 4.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1507 VRGALREF---LQELRSAQRERDELR----TQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQA 1579
Cdd:PRK04863   235 MEAALRENrmtLEAIRVTQSDRDLFKhlitESTNYVAADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMAR 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1580 ELAlqeesvrrsererratldqvaTLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASEsrtvKLELQRR 1659
Cdd:PRK04863   315 ELA---------------------ELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEE----RLEEQNE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1660 SLEGelqrSRLGLSDREAQAQALQDRVDSLQRQVAD-------SEVKAGTLQLTVERLNGA----------LAKVEESEG 1722
Cdd:PRK04863   370 VVEE----ADEQQEENEARAEAAEEEVDELKSQLADyqqaldvQQTRAIQYQQAVQALERAkqlcglpdltADNAEDWLE 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1723 ALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALT-----ACEHDRQVLQerlDAARQALSEARKQSSsLGEQVQTLRGE 1797
Cdd:PRK04863   446 EFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiAGEVSRSEAW---DVARELLRRLREQRH-LAEQLQQLRMR 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1798 VADLElQRVEAEGQLQQLREVLRQRQEgeaaalntvQKLQDErrllqerlgslqrALAQLEAEKREVERSALRLEKDRVA 1877
Cdd:PRK04863   522 LSELE-QRLRQQQRAERLLAEFCKRLG---------KNLDDE-------------DELEQLQEELEARLESLSESVSEAR 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1878 LRRTLDKVEREKLRShedtvrlsaekgrLDRTLTGAELELAEAQRQIQQLEAQvvvleqshSPAQLEvDAQQQQLELQQE 1957
Cdd:PRK04863   579 ERRMALRQQLEQLQA-------------RIQRLAARAPAWLAAQDALARLREQ--------SGEEFE-DSQDVTEYMQQL 636

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 2462515701 1958 VERLRSAqaqtertleareRAHRQRVSTLKGQLQQELRRSSAP 2000
Cdd:PRK04863   637 LEREREL------------TVERDELAARKQALDEEIERLSQP 667
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1516-1931 4.65e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 4.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1516 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERER 1595
Cdd:pfam01576   12 EELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERS 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1596 RATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDR 1675
Cdd:pfam01576   92 QQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEE 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1676 EAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK------- 1748
Cdd:pfam01576  172 EEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEElqaalar 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1749 -------NLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVAD-LELQRVEAEGQLQQLREVLR 1820
Cdd:pfam01576  252 leeetaqKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDtLDTTAAQQELRSKREQEVTE 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1821 QRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLS 1900
Cdd:pfam01576  332 LKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLE 411

                          410       420       430
                   ....*....|....*....|....*....|.
gi 2462515701 1901 AEKGRLDRTLTGAELELAEAQRQIQQLEAQV 1931
Cdd:pfam01576  412 GQLQELQARLSESERQRAELAEKLSKLQSEL 442
COG4995 COG4995
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
532-944 4.72e-03

Uncharacterized conserved protein, contains CHAT domain [Function unknown];


Pssm-ID: 444019 [Multi-domain]  Cd Length: 711  Bit Score: 41.88  E-value: 4.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  532 QLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHS 611
Cdd:COG4995     55 AAALAAAALALALLAAAALALLLLALALAALALALLAAALALALAAAALAALALLAALLALAAAAALLALLAALALLALL 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  612 LQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSR 691
Cdd:COG4995    135 AALAAALAAAAAAALAAALAAAAAAAAAAALLALALALAAAALALLALLLAALAAALAAAAAALALLLALLLLAALAAAL 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  692 ATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQG 771
Cdd:COG4995    215 AAALAALLLALLALAAALLALLLLALLALAAAAAALAAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALA 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  772 RQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELE 851
Cdd:COG4995    295 AAALALALLLAAAAAAALAALALLLLAALLLLLAALALLALLLLLAAAALLAAALAAALALAAALALALLAALLLLLAAL 374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  852 QARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSL--FEVQRQLAQLEARREQ 929
Cdd:COG4995    375 LALLLEALLLLLLALLAALLLLAAALLALAAAQLLRLLLAALALLLALAAYAAARLALLALIeyIILPDRLYAFVQLYQL 454

                          410
                   ....*....|....*
gi 2462515701  930 LEAEGQALLLAKETL 944
Cdd:COG4995    455 LIAPIEAELPGIKRL 469
PTZ00121 PTZ00121
MAEBL; Provisional
 555-775 4.79e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.05  E-value: 4.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  555 QLSDSESERRALEEQLQRLRDKTDGAMQAH-----------EDAQREVQR----LRSANELLSREKSNLAHSLQVAQQ-- 617
Cdd:PTZ00121  1526 EAKKAEEAKKADEAKKAEEKKKADELKKAEelkkaeekkkaEEAKKAEEDknmaLRKAEEAKKAEEARIEEVMKLYEEek 1605

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  618 --QAEELRQ-EREKLQAAQ----EELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR---- 686
Cdd:PTZ00121  1606 kmKAEEAKKaEEAKIKAEElkkaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKkaee 1685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  687 ------EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSmtKLRAEEASLQDSLSKLSAlnESLAQDKLDLNRlVA 760
Cdd:PTZ00121  1686 dekkaaEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEEN--KIKAEEAKKEAEEDKKKA--EEAKKDEEEKKK-IA 1760

                          250
                   ....*....|....*..
gi 2462515701  761 QL--EEEKSALQGRQRQ 775
Cdd:PTZ00121  1761 HLkkEEEKKAEEIRKEK 1777
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
613-941 4.99e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 4.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  613 QVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEdavqdgarvrrELERSHRQLEQLEGKRSVLAKELVEVREALSRA 692
Cdd:COG4372     24 ILIAALSEQLRKALFELDKLQEELEQLREELEQARE-----------ELEQLEEELEQARSELEQLEEELEELNEQLQAA 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  693 TLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGR 772
Cdd:COG4372     93 QAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  773 QRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQ 852
Cdd:COG4372    173 LQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELL 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  853 ARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEA 932
Cdd:COG4372    253 EEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELAL 332


                   ....*....
gi 2462515701  933 EGQALLLAK 941
Cdd:COG4372    333 AILLAELAD 341
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1767-1990 5.01e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 5.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1767 QERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQER 1846
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1847 LGSLQRALAQLEA------------------EKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDR 1908
Cdd:COG4942     99 LEAQKEELAELLRalyrlgrqpplalllspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1909 TLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQeverlRSAQAQTERTLEARERAHRQRVSTLKG 1988
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE-----ALIARLEAEAAAAAERTPAAGFAALKG 253


                   ..
gi 2462515701 1989 QL 1990
Cdd:COG4942    254 KL 255
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1517-1874 5.41e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 5.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1517 ELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERR 1596
Cdd:pfam01576  216 ESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRR 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1597 ATLDQVATLERSLQATESELRASQEKISKMKANETKL-----EGDKRRLKEVLDASESRTVKLELQRRSLEgELQRSRLG 1671
Cdd:pfam01576  296 DLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELkkaleEETRSHEAQLQEMRQKHTQALEELTEQLE-QAKRNKAN 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1672 LSDR----EAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRD 1747
Cdd:pfam01576  375 LEKAkqalESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEG 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1748 KNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEA 1827
Cdd:pfam01576  455 KNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLE 534

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 2462515701 1828 AALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKD 1874
Cdd:pfam01576  535 EDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQE 581
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 825-947 5.74e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.61  E-value: 5.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  825 LRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEalERAAREKEALAKEHAGLAvQLVAAEREGRTLSEEATRLRL 904
Cdd:COG0542    402 VRMEIDSKPEELDELERRLEQLEIEKEALKKEQDEASF--ERLAELRDELAELEEELE-ALKARWEAEKELIEEIQELKE 478

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 2462515701  905 EKEALEGSLFEVQRQLAQLEARREQLEAegqallLAKETLTGE 947
Cdd:COG0542    479 ELEQRYGKIPELEKELAELEEELAELAP------LLREEVTEE 515
COG1754 COG1754
Uncharacterized C-terminal domain of topoisomerase IA [Function unknown];
1153-1498 5.81e-03

Uncharacterized C-terminal domain of topoisomerase IA [Function unknown];


Pssm-ID: 441360 [Multi-domain]  Cd Length: 892  Bit Score: 41.73  E-value: 5.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1153 LREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESE 1232
Cdd:COG1754    137 LLRRRLVLRRLVRRLLVRLLLLRLVLLLLRLLVARRAARRRRRRRRRRARRRELERRRERARAAEAEEAAAAAAAAADAG 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1233 RISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMldSENTRLGRELAELQGRLAL 1312
Cdd:COG1754    217 RAAAARDGKGGGKLAAGGAAAAAAAAAAAAAAAAALAEAAAAAAVREPPTPTTTTTAQA--ATTTTTRAAAARTTRSAQQ 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1313 GERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLE 1392
Cdd:COG1754    295 AARRTRLGGEGTYTTTTTTTTTTSAAAAAAAAAAAALAAAAAAAYAPPPPYYYKKKAAAAAAAAAAAAAAAARRPPAARA 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1393 AARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLR----SALRRGLGLGRAPSPAPRPVPGSPARDAPAE 1468
Cdd:COG1754    375 ALLSDDRLLLELLLLRRTAAAAAAAAAATATTTAAAAAAGAGAVGtaaaGAVFFFGGFLLFAEEEDDDEEDDDDDDLPAL 454

                          330       340       350
                   ....*....|....*....|....*....|
gi 2462515701 1469 GSGEGLNSPSTLECSPGSQPPSPGPATSPA 1498
Cdd:COG1754    455 EEGLPLLKEGVLADQHFTQPPPRYTEAPLV 484
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1511-1946 6.25e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 6.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1511 LREFLQELRSAQRERDELRTQTSALNRQLAEMEAErdsaTSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRR 1590
Cdd:TIGR04523  175 LNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKK----IQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISN 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1591 SERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELqrRSLEGELQRSRL 1670
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSEL--KNQEKKLEEIQN 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1671 GLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTealaqssaslNSTRDKNL 1750
Cdd:TIGR04523  329 QISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE----------SQINDLES 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1751 HLQKAltacEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAAL 1830
Cdd:TIGR04523  399 KIQNQ----EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLS 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1831 NTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTL 1910
Cdd:TIGR04523  475 RSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFEL 554

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 2462515701 1911 TGAELE--LAEAQRQIQQLEAQVVVLEQSHSPAQLEVD 1946
Cdd:TIGR04523  555 KKENLEkeIDEKNKEIEELKQTQKSLKKKQEEKQELID 592
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1658-1850 6.76e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.58  E-value: 6.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1658 RRSLEGELQRSRLGLSDREAQAQAlqdRVDSLQRQVADSEVKagtLQLTVERLNGAlaKVEESEGALRDkvrglTEALAQ 1737
Cdd:PRK10929   185 LKALVDELELAQLSANNRQELARL---RSELAKKRSQQLDAY---LQALRNQLNSQ--RQREAERALES-----TELLAE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1738 SSASLNSTRDKNLHLQKALT------ACEHDRQVLQERLDAA-----RQALSEARKQ------SSSLGE----QV----- 1791
Cdd:PRK10929   252 QSGDLPKSIVAQFKINRELSqalnqqAQRMDLIASQQRQAASqtlqvRQALNTLREQsqwlgvSNALGEalraQVarlpe 331

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462515701 1792 ----QTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGeAAALNTVQK--LQDERRLLQERLGSL 1850
Cdd:PRK10929   332 mpkpQQLDTEMAQLRVQRLRYEDLLNKQPQLRQIRQAD-GQPLTAEQNriLDAQLRTQRELLNSL 395
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
744-1083 7.30e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.04  E-value: 7.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  744 LNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLP 823
Cdd:COG4372      4 LGEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELE 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  824 TLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLR 903
Cdd:COG4372     84 ELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQ 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  904 LEKEALEGSLfeVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQAS 983
Cdd:COG4372    164 EELAALEQEL--QALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDA 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  984 LREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA 1063
Cdd:COG4372    242 LELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAAL 321

                          330       340
                   ....*....|....*....|
gi 2462515701 1064 LSLKESEKTALSEKLMGTRH 1083
Cdd:COG4372    322 LELAKKLELALAILLAELAD 341
PRK09039 PRK09039
peptidoglycan -binding protein;
839-960 7.96e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 40.72  E-value: 7.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  839 LSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGrtlseeaTRLRLEKEALEGSLFEVQR 918
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAER-------SRLQALLAELAGAGAAAEG 116

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 2462515701  919 QLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQE 960
Cdd:PRK09039   117 RAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEA 158
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
808-1016 8.61e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 40.83  E-value: 8.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  808 LRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR-QLS-GREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQL 885
Cdd:COG0497    167 WRALKKELEELRADEAERARELDLLRFQLEELEAaALQpGEEEELEEERRRLSNAEKLREALQEALEALSGGEGGALDLL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  886 VAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALllakETLTGELAGLRQ----------QI 955
Cdd:COG0497    247 GQALRALERLAEYDPSLAELAERLESALIELEEAASELRRYLDSLEFDPERL----EEVEERLALLRRlarkygvtveEL 322

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462515701  956 IATQEKasldkelMAQKLVQAEreaqaslreqraAHEEDLQRLQREKEAAWRELEAERAQL 1016
Cdd:COG0497    323 LAYAEE-------LRAELAELE------------NSDERLEELEAELAEAEAELLEAAEKL 364
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 560-1310 9.68e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 40.93  E-value: 9.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  560 ESERRALEEQLQRLRDKTDGAMQAH----EDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEE 635
Cdd:pfam01576  337 EEETRSHEAQLQEMRQKHTQALEELteqlEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQE 416

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  636 LRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRAtlqRDMLQAEKAEVAEALTKAEA 715
Cdd:pfam01576  417 LQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDT---QELLQEETRQKLNLSTRLRQ 493

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  716 GRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEeeksALQGRQRQAEQEATVAREEQERLEELRL 795
Cdd:pfam01576  494 LEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLE----ALEEGKKRLQRELEALTQQLEEKAAAYD 569

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  796 EQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAqrqvealeraaREKEALA 875
Cdd:pfam01576  570 KLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEA-----------REKETRA 638

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  876 kehAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGEL-----AG 950
Cdd:pfam01576  639 ---LSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELqatedAK 715

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701  951 LRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWR-ELEAERAQLQSQL------QRE 1023
Cdd:pfam01576  716 LRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKkKLELDLKELEAQIdaankgREE 795

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1024 QEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLkESEKTALSEKLMGTRHSLATISLEMErQKRDAQSRQ 1103
Cdd:pfam01576  796 AVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNL-EAELLQLQEDLAASERARRQAQQERD-ELADEIASG 873

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1104 EQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRK 1183
Cdd:pfam01576  874 ASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAK 953

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462515701 1184 LRE-SQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAG 1262
Cdd:pfam01576  954 LQEmEGTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAEKGNSRMK 1033

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 2462515701 1263 ELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRL 1310
Cdd:pfam01576 1034 QLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSKL 1081
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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