NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2462598869|ref|XP_054206804|]
View 

DNA transposase THAP9 isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Tnp_P_element super family cl20443
Transposase protein; Protein in this family are transposases found in insects. This region is ...
72-244 4.61e-03

Transposase protein; Protein in this family are transposases found in insects. This region is about 230 amino acids in length and is found associated with pfam05485.


The actual alignment was detected with superfamily member pfam12017:

Pssm-ID: 288840  Cd Length: 219  Bit Score: 39.40  E-value: 4.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462598869  72 ACTLYLCSSKVYDYVRKILK--LPHSSILRTWLSKCQPSPGFNSNIFSFLQRRVENGDQLYQYCSLLIKSIPLKQQLQWD 149
Cdd:pfam12017  63 AFTLRYFSKRAYVYLKNELNypLPGLSTLQRWAKTIEMRNGILEDVLNLMKLKGDQLNDYEKLTVLMFDEVKISNTMEYD 142
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462598869 150 PSSHSFQGfmdfglgkldadetpLASETVLLMAVGIFGHWRTPLGYFFVNRasgyLQAQLLRLTIGKLSDIGITVLAVTS 229
Cdd:pfam12017 143 KLRDEVIG---------------PHNQMQVVMARGVASNWKQPIFVDFDKK----MTKEILFDIIEKLDKIGFKVISCVS 203
                         170
                  ....*....|....*
gi 2462598869 230 DATAHSVQMAKALGI 244
Cdd:pfam12017 204 DMGGGNVSLWKALDI 218
 
Name Accession Description Interval E-value
Tnp_P_element pfam12017
Transposase protein; Protein in this family are transposases found in insects. This region is ...
72-244 4.61e-03

Transposase protein; Protein in this family are transposases found in insects. This region is about 230 amino acids in length and is found associated with pfam05485.


Pssm-ID: 288840  Cd Length: 219  Bit Score: 39.40  E-value: 4.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462598869  72 ACTLYLCSSKVYDYVRKILK--LPHSSILRTWLSKCQPSPGFNSNIFSFLQRRVENGDQLYQYCSLLIKSIPLKQQLQWD 149
Cdd:pfam12017  63 AFTLRYFSKRAYVYLKNELNypLPGLSTLQRWAKTIEMRNGILEDVLNLMKLKGDQLNDYEKLTVLMFDEVKISNTMEYD 142
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462598869 150 PSSHSFQGfmdfglgkldadetpLASETVLLMAVGIFGHWRTPLGYFFVNRasgyLQAQLLRLTIGKLSDIGITVLAVTS 229
Cdd:pfam12017 143 KLRDEVIG---------------PHNQMQVVMARGVASNWKQPIFVDFDKK----MTKEILFDIIEKLDKIGFKVISCVS 203
                         170
                  ....*....|....*
gi 2462598869 230 DATAHSVQMAKALGI 244
Cdd:pfam12017 204 DMGGGNVSLWKALDI 218
 
Name Accession Description Interval E-value
Tnp_P_element pfam12017
Transposase protein; Protein in this family are transposases found in insects. This region is ...
72-244 4.61e-03

Transposase protein; Protein in this family are transposases found in insects. This region is about 230 amino acids in length and is found associated with pfam05485.


Pssm-ID: 288840  Cd Length: 219  Bit Score: 39.40  E-value: 4.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462598869  72 ACTLYLCSSKVYDYVRKILK--LPHSSILRTWLSKCQPSPGFNSNIFSFLQRRVENGDQLYQYCSLLIKSIPLKQQLQWD 149
Cdd:pfam12017  63 AFTLRYFSKRAYVYLKNELNypLPGLSTLQRWAKTIEMRNGILEDVLNLMKLKGDQLNDYEKLTVLMFDEVKISNTMEYD 142
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462598869 150 PSSHSFQGfmdfglgkldadetpLASETVLLMAVGIFGHWRTPLGYFFVNRasgyLQAQLLRLTIGKLSDIGITVLAVTS 229
Cdd:pfam12017 143 KLRDEVIG---------------PHNQMQVVMARGVASNWKQPIFVDFDKK----MTKEILFDIIEKLDKIGFKVISCVS 203
                         170
                  ....*....|....*
gi 2462598869 230 DATAHSVQMAKALGI 244
Cdd:pfam12017 204 DMGGGNVSLWKALDI 218
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH