|
Name |
Accession |
Description |
Interval |
E-value |
| BRCT_MDC1_rpt2 |
cd18441 |
second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; ... |
1752-1832 |
1.52e-43 |
|
second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the second BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is not conserved in this family.
Pssm-ID: 349394 Cd Length: 81 Bit Score: 152.92 E-value: 1.52e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1752 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEA 1831
Cdd:cd18441 1 LLEGYEIHVTPGVKPEPPQMKDIITCAGGTFLPSMPKTYKPQTVVISCPEDFPHCSPALKAGLPVVSAEFLLTGILRQEA 80
|
.
gi 2462611565 1832 K 1832
Cdd:cd18441 81 D 81
|
|
| FHA_MDC1 |
cd22665 |
forkhead associated (FHA) domain found in mediator of DNA damage checkpoint protein 1 (MDC1) ... |
53-152 |
9.91e-38 |
|
forkhead associated (FHA) domain found in mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also called nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438717 [Multi-domain] Cd Length: 97 Bit Score: 136.98 E-value: 9.91e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 53 GRLHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAwdKAPILRDCGSLNGTQIlRPPKVLSPGV 132
Cdd:cd22665 1 GRLKVFSQAHGPEKDFPLYEGENVIGRDPSCSVVLPDKSVSKQHACIEVDG--GTHLIEDLGSTNGTRI-GNKVRLKPNV 77
|
90 100
....*....|....*....|
gi 2462611565 133 SHRLRDQELILFADLLCQYH 152
Cdd:cd22665 78 RYELIDGDLLLFGDVKCQYV 97
|
|
| BRCT_MDC1_rpt1 |
cd17744 |
first BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; ... |
1650-1720 |
1.85e-27 |
|
first BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the first BRCT domain.
Pssm-ID: 349375 [Multi-domain] Cd Length: 72 Bit Score: 106.93 E-value: 1.85e-27
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462611565 1650 PKVLFTGVVD-ARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1720
Cdd:cd17744 1 PRVLFTGVSDkEEGEKIIKKLGGSVVDSVEDCTHLVTDKVRRTVKFLCALARGIPIVSPDWLEASIKANKFL 72
|
|
| BRCT_PAXIP1_rpt6_like |
cd18432 |
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1), second BRCT domain of mediator of DNA ... |
1752-1830 |
1.34e-26 |
|
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1), second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the sixth BRCT domain of PAXIP1 and the second BRCT domain of MDC1.
Pssm-ID: 349385 [Multi-domain] Cd Length: 85 Bit Score: 104.97 E-value: 1.34e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1752 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMP----RSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVL 1827
Cdd:cd18432 1 LFEGYTFYVTPNVKPPPEELKEIIEAAGGKVLKKLPtkriEDDDPDTIVISCEEDRKLWKPLKKKGIPIYSVEFILTGIL 80
|
...
gi 2462611565 1828 KQE 1830
Cdd:cd18432 81 RQK 83
|
|
| BRCT_PAXIP1_rpt5 |
cd17712 |
fifth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also ... |
1649-1720 |
1.92e-20 |
|
fifth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. This family corresponds to the fifth BRCT domain.
Pssm-ID: 349344 Cd Length: 75 Bit Score: 86.91 E-value: 1.92e-20
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462611565 1649 APKVLFTGVVDARGER---AVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1720
Cdd:cd17712 1 TPRVLFTGFDPVQVRKltkKVTILGGEVVESPQECTHLVAPKVSRTVKFLTAISVCKHIVTPEWLEESFKQGKFL 75
|
|
| BRCT_PAXIP1_rpt6 |
cd18440 |
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also ... |
1752-1830 |
7.74e-20 |
|
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. This family corresponds to the sixth BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is not conserved in this family.
Pssm-ID: 349393 Cd Length: 90 Bit Score: 85.73 E-value: 7.74e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1752 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSmPRSYKPQR----------VVITCPQDFPHCSIPLRVGLPLLSPEF 1821
Cdd:cd18440 1 LFKGKYFYITPGVKPSPSVLKEIIESAGGKVEKK-RPSLKKIMeknnqgppsyIIITCENDLHLCRDLFRKNIDVYNAEF 79
|
....*....
gi 2462611565 1822 LLTGVLKQE 1830
Cdd:cd18440 80 ILTGVLRQK 88
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
984-1514 |
1.62e-17 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 90.00 E-value: 1.62e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 984 ATRGRKNRSSVKTPEPVVPTAP-ELQPSTSTDQPVtSEPTYQAT----RGRKNRSSVKTPEPVVPTAPELRPSTsTDRPV 1058
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPsRLAPAILPDEPV-GEPVHPRMltwiRGLEELASDDAGDPPPPLPPAAPPAA-PDRSV 2568
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1059 -TPKPTSRttrsrtnmssvktpetvvPTAPELQiSTSTDQPVTPKPTsrttRSRTNMSSVKNPESTVPIAPeLPPSTSTE 1137
Cdd:PHA03247 2569 pPPRPAPR------------------PSEPAVT-SRARRPDAPPQSA----RPRAPVDDRGDPRGPAPPSP-LPPDTHAP 2624
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1138 QPVTPEPTSRATRGRKNRSSGKTP---ETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSvktPETVVPTAPELQP 1214
Cdd:PHA03247 2625 DPPPPSPSPAANEPDPHPPPTVPPperPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAA---RPTVGSLTSLADP 2701
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1215 StstDQPVTPEPTSQATrgrtdrsSVKTPETVVPTAPELQASASTDQPVTSEP--TSRTTRGRKNRSSVKTPETVVPAAP 1292
Cdd:PHA03247 2702 P---PPPPTPEPAPHAL-------VSATPLPPGPAAARQASPALPAAPAPPAVpaGPATPGGPARPARPPTTAGPPAPAP 2771
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1293 ELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESivPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPT 1372
Cdd:PHA03247 2772 PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPAD--PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPS 2849
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1373 AP-----EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVR 1447
Cdd:PHA03247 2850 LPlggsvAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQP 2929
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462611565 1448 AMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQR 1514
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPL 2996
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
777-1397 |
1.06e-14 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 80.37 E-value: 1.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 777 IRAAEKVSRGDQESPDACLPPTVPeAPAPPQKPLNSQSQKHLAPPPLlspllpsikpTVRKTRqdgsqeaPEAPlsseLE 856
Cdd:PHA03247 2537 IRGLEELASDDAGDPPPPLPPAAP-PAAPDRSVPPPRPAPRPSEPAV----------TSRARR-------PDAP----PQ 2594
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 857 PFHPKPKIRTRKSSRMTPfPATSAAPEPHPststaqpvtPKPTSQATRSRTNRSSVKTPepvVPTAPELQPSTSTDQPVT 936
Cdd:PHA03247 2595 SARPRAPVDDRGDPRGPA-PPSPLPPDTHA---------PDPPPPSPSPAANEPDPHPP---PTVPPPERPRDDPAPGRV 2661
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 937 SEPTSQVTRGRKSRSSvKTPETVVPTALE--LQPSTSTDRPVTSEPTSQAtrgRKNRSSVKTPEPVVPTAPELQPSTSTD 1014
Cdd:PHA03247 2662 SRPRRARRLGRAAQAS-SPPQRPRRRAARptVGSLTSLADPPPPPPTPEP---APHALVSATPLPPGPAAARQASPALPA 2737
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1015 QPVT-SEPTYQATRGRKNRssvkTPEPVVPTAPElRPSTSTDRPVTPKPtsRTTRSRTNMSSVKTPETVVPTAPelqist 1093
Cdd:PHA03247 2738 APAPpAVPAGPATPGGPAR----PARPPTTAGPP-APAPPAAPAAGPPR--RLTRPAVASLSESRESLPSPWDP------ 2804
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1094 STDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSteQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEP 1173
Cdd:PHA03247 2805 ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPP--PPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPP 2882
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1174 STSTDQPVTPEPTSqatrgrtnrssvktPETVVPTAPELQPSTSTDQPVTPEPTSQAtrgrtdrSSVKTPETVVPTAPEL 1253
Cdd:PHA03247 2883 VRRLARPAVSRSTE--------------SFALPPDQPERPPQPQAPPPPQPQPQPPP-------PPQPQPPPPPPPRPQP 2941
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1254 QASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSvktpESIVPIAP 1333
Cdd:PHA03247 2942 PLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWAS----SLALHEET 3017
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462611565 1334 ELQPSTSRNQLVTPEPT--SRATRCRTNRSSVKTPEPVVPTAPEPH-PTTSTDQPVTPKLTSRATRR 1397
Cdd:PHA03247 3018 DPPPVSLKQTLWPPDDTedSDADSLFDSDSERSDLEALDPLPPEPHdPFAHEPDPATPEAGARESPS 3084
|
|
| FHA |
cd00060 |
forkhead associated (FHA) domain superfamily; Forkhead-associated (FHA) domains are small ... |
54-131 |
9.12e-14 |
|
forkhead associated (FHA) domain superfamily; Forkhead-associated (FHA) domains are small phosphopeptide recognition modules mostly found in eubacteria and eukaryotes. It is about 95-120 residues long that fold into an 11-stranded beta-sandwich. FHA domains can mediate the recognition of phosphorylated and non-phosphorylated substrates, as well as protein oligomerization. They specifically recognize threonine phosphorylation (pThr) accompanying activation of protein serine/threonine kinases. FHA domains show diverse ligand specificity. They may recognize the pTXXD motif, the pTXXI/L motif, and TQ clusters (singly and multiply phosphorylated). In eukaryotes, FHA superfamily members include forkhead-type transcription factors, as well as other signaling proteins, such as many regulatory proteins, kinases, phosphatases, motor proteins called kinesins, and metabolic enzymes. Many of them localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. FHA domains play important roles in human diseases, particularly in relation to DNA damage responses and cancers. In bacteria, FHA domain-containing proteins may participate in injection of viral proteins into host cells, transmembrane transporters, and cell division. FHA domain-containing proteins rarely include more than one copy of the domain. The only exception in eukaryotes is the checkpoint kinase Rad53 from Saccharomyces cerevisiae, which harbors two FHA domains (FHA1 and FHA2) flanking a central kinase domain. The two FHA domains recognize different phosphorylated targets and function independently from one another. In contrast, Mycobacterium tuberculosis ABC transporter Rv1747 contains two FHA domains but only one of them is essential for protein function.
Pssm-ID: 438714 [Multi-domain] Cd Length: 92 Bit Score: 68.46 E-value: 9.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 54 RLHIFSGAHGPEKdFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQI----LRPPKVLS 129
Cdd:cd00060 1 RLIVLDGDGGGRE-FPLTKGVVTIGRSPDCDIVLDDPSVSRRHARIEVD--GGGVYLEDLGSTNGTFVngkrITPPVPLQ 77
|
..
gi 2462611565 130 PG 131
Cdd:cd00060 78 DG 79
|
|
| FHA |
COG1716 |
Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]; |
53-131 |
1.96e-13 |
|
Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms];
Pssm-ID: 441322 [Multi-domain] Cd Length: 96 Bit Score: 67.68 E-value: 1.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 53 GRLHIFSGAHGpEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEilAWDKAPILRDCGSLNGTQI----LRPPKVL 128
Cdd:COG1716 2 ARLVVLEGPLA-GRRFPLDGGPLTIGRAPDNDIVLDDPTVSRRHARIR--RDGGGWVLEDLGSTNGTFVngqrVTEPAPL 78
|
...
gi 2462611565 129 SPG 131
Cdd:COG1716 79 RDG 81
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1119-1587 |
3.42e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 75.75 E-value: 3.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1119 NPESTVPIAPELPPSTSTEQP--VTPEPTSRATRGR-----------KNRSSGKTPETLVPTAPKLEPSTSTDQP-VTPE 1184
Cdd:PHA03247 2497 DPGGGGPPDPDAPPAPSRLAPaiLPDEPVGEPVHPRmltwirgleelASDDAGDPPPPLPPAAPPAAPDRSVPPPrPAPR 2576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1185 PTSQATRGRTNRSSVKtPETVVPTAPeLQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1264
Cdd:PHA03247 2577 PSEPAVTSRARRPDAP-PQSARPRAP-VDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRD 2654
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1265 SEPTSRTTRGRKNRSSVKTPEtvvPAAPELQPSTSTDQPVTPEPTSRATrgrtnrssvktpesivPIAPELQPSTSRNQL 1344
Cdd:PHA03247 2655 DPAPGRVSRPRRARRLGRAAQ---ASSPPQRPRRRAARPTVGSLTSLAD----------------PPPPPPTPEPAPHAL 2715
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1345 VTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPV-TPKLTSRATRRKTNRSSVKTPKP--VEPAASDLEPFT 1421
Cdd:PHA03247 2716 VSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPaRPPTTAGPPAPAPPAAPAAGPPRrlTRPAVASLSESR 2795
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1422 PTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSA 1501
Cdd:PHA03247 2796 ESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKP 2875
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1502 PLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSrkrSLATMDSPPHQ 1581
Cdd:PHA03247 2876 AAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQP---PLAPTTDPAGA 2952
|
....*.
gi 2462611565 1582 KQPQRG 1587
Cdd:PHA03247 2953 GEPSGA 2958
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
768-1313 |
1.00e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.20 E-value: 1.00e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 768 MPPAEKASRirAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAP 847
Cdd:PHA03247 2568 VPPPRPAPR--PSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPT 2645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 848 EAPLSSELEPFHPkPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQP 927
Cdd:PHA03247 2646 VPPPERPRDDPAP-GRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 928 STSTDQPVTSEPTSQVtrgrksrssvkTPETVVPTALELQPSTSTDRPVTSEPtsqatrgrknrssvktPEPVVPTAPEL 1007
Cdd:PHA03247 2725 PAAARQASPALPAAPA-----------PPAVPAGPATPGGPARPARPPTTAGP----------------PAPAPPAAPAA 2777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1008 QPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPET----VV 1083
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlggsVA 2857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1084 PTAPELQISTStdQPVTPKPTSRTTRSRTNMSSVKNPESTVPIApeLPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPET 1163
Cdd:PHA03247 2858 PGGDVRRRPPS--RSPAAKPAAPARPPVRRLARPAVSRSTESFA--LPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1164 LVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKT- 1242
Cdd:PHA03247 2934 PPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLAl 3013
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462611565 1243 -PETVVPTAPELQASASTDQPVTSEPTSRttrgRKNRSSVKTPETVVPAAPELQ-PSTSTDQPVTPEPTSRAT 1313
Cdd:PHA03247 3014 hEETDPPPVSLKQTLWPPDDTEDSDADSL----FDSDSERSDLEALDPLPPEPHdPFAHEPDPATPEAGARES 3082
|
|
| BRCT_BRC1_like_rpt5 |
cd17743 |
fifth BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar ... |
1651-1717 |
1.77e-12 |
|
fifth BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins; Schizosaccharomyces pombe BRC1 is required for mitotic fidelity, specifically in the G2 phase of the cell cycle. It plays a role in chromatin organization. The family also includes Cryptococcus neoformans DNA ligase 4 (LIG4, also known as DNA ligase IV or polydeoxyribonucleotide synthase [ATP] 4), which is involved in dsDNA break repair, and plays a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologus end-joining. Members in this family contain six BRCT domains. This family corresponds to the fifth one.
Pssm-ID: 349374 Cd Length: 70 Bit Score: 64.19 E-value: 1.77e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462611565 1651 KVLFTGVVDARGE--RAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1717
Cdd:cd17743 2 RLLFTGYKLWTEKeiKKLKKLGISIVEDPDECTHLVAPKIVRTEKFLCALAYAPVIVTTDWLEACLKAG 70
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
877-1217 |
2.57e-12 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 72.26 E-value: 2.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 877 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTApelQPSTSTDQPVTSEPTSQVTR---GRKSRSSV 953
Cdd:pfam05109 471 ADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTP---TPNATSPTPAVTTPTPNATSptlGKTSPTSA 547
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 954 KTPETvvPTALELQPSTSTDRPVTSEPTSQATrgrKNRSSVKTPEP--VVPTAPELQPSTST---------DQPVTSEP- 1021
Cdd:pfam05109 548 VTTPT--PNATSPTPAVTTPTPNATIPTLGKT---SPTSAVTTPTPnaTSPTVGETSPQANTtnhtlggtsSTPVVTSPp 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1022 ---TYQATRGRKNRSSVKTpepvvpTAPELRPStSTDRPVTPKPTSRTTRSRTNMSSVKTP--ETVVPTAPElqiSTSTD 1096
Cdd:pfam05109 623 knaTSAVTTGQHNITSSST------SSMSLRPS-SISETLSPSTSDNSTSHMPLLTSAHPTggENITQVTPA---STSTH 692
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1097 QPVT----PKPTSRTTRSRTNMSSVKNPESTVPIAPELPP--STSTEQPV---TPEPTSRATRGRKNRSSGKTPETLVPT 1167
Cdd:pfam05109 693 HVSTsspaPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPknATSPQAPSgqkTAVPTVTSTGGKANSTTGGKHTTGHGA 772
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462611565 1168 APKLEPST----STDQPVT--------PEPTSQATRGRTNRSS--VKTPETVVPTAPELQPSTS 1217
Cdd:pfam05109 773 RTSTEPTTdyggDSTTPRTrynattylPPSTSSKLRPRWTFTSppVTTAQATVPVPPTSQPRFS 836
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1079-1440 |
2.35e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 69.17 E-value: 2.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1079 PETVVPTAPELQISTSTDQPVTPK-PTSRTTRSRTNMSSVKNPESTVPiapeLPPSTSTEQPVTPEPtsratrgrknrSS 1157
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKVIFSKaPESTTTSPTLNTTGFAAPNTTTG----LPSSTHVPTNLTAPA-----------ST 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1158 GKTPETLVPTAPKLEPSTSTDQPVTPEPTSqatrgRTNRSSVKTPETVVPTAPELQPSTSTDQP----VTPEPTSQA-TR 1232
Cdd:pfam05109 465 GPTVSTADVTSPTPAGTTSGASPVTPSPSP-----RDNGTESKAPDMTSPTSAVTTPTPNATSPtpavTTPTPNATSpTL 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1233 GRTDRSSVKTPETvvPTAPELQASASTDQPVTSEPTSRTTrGRKNRSSVKTPETVVPAAPELQPSTST---------DQP 1303
Cdd:pfam05109 540 GKTSPTSAVTTPT--PNATSPTPAVTTPTPNATIPTLGKT-SPTSAVTTPTPNATSPTVGETSPQANTtnhtlggtsSTP 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1304 VTPEP----TSRATRGRTNRSSVKTPE-SIVP--IAPELQPSTSRNQ------LVTPEPTSRATRCRTNRSSVKTpEPVV 1370
Cdd:pfam05109 617 VVTSPpknaTSAVTTGQHNITSSSTSSmSLRPssISETLSPSTSDNStshmplLTSAHPTGGENITQVTPASTST-HHVS 695
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462611565 1371 PTAPEPHPTTsTDQPVTPKLTSRATrrKTNRSSVKTPKPVEPAASdlePFTPTDQ-SVTPEAIAQGGQSKT 1440
Cdd:pfam05109 696 TSSPAPRPGT-TSQASGPGNSSTST--KPGEVNVTKGTPPKNATS---PQAPSGQkTAVPTVTSTGGKANS 760
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1037-1475 |
2.76e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 68.79 E-value: 2.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1037 TPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPElqiSTSTDQPVTPKPTSRTTRSRTNMSS 1116
Cdd:pfam05109 429 TTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTPAG---TTSGASPVTPSPSPRDNGTESKAPD 505
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1117 VKNPESTVPIApelPPSTSTEQPVTPEPTSRATrgrkNRSSGKTPETLVPTAPKlePSTSTDQPVTPEPTSQATRGRTNR 1196
Cdd:pfam05109 506 MTSPTSAVTTP---TPNATSPTPAVTTPTPNAT----SPTLGKTSPTSAVTTPT--PNATSPTPAVTTPTPNATIPTLGK 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1197 SSvktpetvvPTAPELQPSTSTDQPVTPEPTSQA-TRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGR 1275
Cdd:pfam05109 577 TS--------PTSAVTTPTPNATSPTVGETSPQAnTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRP 648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1276 KNRSSVKTPETVVPAAPELqPSTSTDQPVTPEPTSRATRGRTNRSSVKTPesivpiAPELQPSTsrnqlvtpepTSRATR 1355
Cdd:pfam05109 649 SSISETLSPSTSDNSTSHM-PLLTSAHPTGGENITQVTPASTSTHHVSTS------SPAPRPGT----------TSQASG 711
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1356 CRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKL---TSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAI 1432
Cdd:pfam05109 712 PGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTavpTVTSTGGKANSTTGGKHTTGHGARTSTEPTTDYGGDSTTPRT 791
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2462611565 1433 AQGGQSKTLRSSTVRAMPVPTTPefQSPVTTDQPISP-EPITQP 1475
Cdd:pfam05109 792 RYNATTYLPPSTSSKLRPRWTFT--SPPVTTAQATVPvPPTSQP 833
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
860-1267 |
4.44e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 68.02 E-value: 4.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 860 PKPKIRTRKSSRMTPFPAT---SAAPEPHPSTST------AQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPS-- 928
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKvifSKAPESTTTSPTlnttgfAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTpa 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 929 --TSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTAlelQPSTSTDRPVTSEPTSQATRGRKNRSS----VKTPepvVP 1002
Cdd:pfam05109 480 gtTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTP---TPNATSPTPAVTTPTPNATSPTLGKTSptsaVTTP---TP 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1003 TAPELQPSTSTDQPVTSEPTYQATrgrKNRSSVKTPEP--VVPTAPELRPSTSTDRPVTPKPTSR---TTRSRTNMSSVK 1077
Cdd:pfam05109 554 NATSPTPAVTTPTPNATIPTLGKT---SPTSAVTTPTPnaTSPTVGETSPQANTTNHTLGGTSSTpvvTSPPKNATSAVT 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1078 TPETVVPTAPELQIS---TSTDQPVTPKpTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEP------TSRA 1148
Cdd:pfam05109 631 TGQHNITSSSTSSMSlrpSSISETLSPS-TSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPaprpgtTSQA 709
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1149 TRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPV---TPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTS-TDQPVTP 1224
Cdd:pfam05109 710 SGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSgqkTAVPTVTSTGGKANSTTGGKHTTGHGARTSTEPTTDyGGDSTTP 789
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2462611565 1225 EPTSQATRGRTDRSSVK-TPETVVPTAPELQASASTDQPVTSEP 1267
Cdd:pfam05109 790 RTRYNATTYLPPSTSSKlRPRWTFTSPPVTTAQATVPVPPTSQP 833
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1107-1493 |
7.15e-11 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 66.91 E-value: 7.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1107 TTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTStdqPVTPEPT 1186
Cdd:pfam17823 53 KSSEQ*NFCAATAAPAPVTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSS---PSSAAQS 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1187 SQATRGRTNRSSVKTPETVVPTAP-ELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTS 1265
Cdd:pfam17823 130 LPAAIAALPSEAFSAPRAAACRANaSAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1266 EPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSR-ATRGRTNRSSVKTPESIVPIAPELQPST---SR 1341
Cdd:pfam17823 210 RGISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATlAAAAGTVASAAGTINMGDPHARRLSPAKhmpSD 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1342 NQLVTPEPTSRAtRCRTNRSSVKTPEPVVPTAPEPHPTtstdqpvtpkltsratrrktnrssvktpkpvePAASDLEPFT 1421
Cdd:pfam17823 290 TMARNPAAPMGA-QAQGPIIQVSTDQPVHNTAGEPTPS--------------------------------PSNTTLEPNT 336
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462611565 1422 PTDQSVTPEAIAQGGQSKTLRSStvrAMPVPTTPEFQSPVTTdqpiSPEPITQPSCIKRQRAAGNPGSLAAP 1493
Cdd:pfam17823 337 PKSVASTNLAVVTTTKAQAKEPS---ASPVPVLHTSMIPEVE----ATSPTTQPSPLLPTQGAAGPGILLAP 401
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1230-1678 |
7.59e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 67.66 E-value: 7.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1230 ATRGRTDRSSVKTPETVVPTAPELQASAS-TDQPVTSEPTSRT---TRGRKNRSSVKTPETVVPAAPELQPSTsTDQPV- 1304
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPSRLAPAIlPDEPVGEPVHPRMltwIRGLEELASDDAGDPPPPLPPAAPPAA-PDRSVp 2569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1305 ----TPEPTSRATRGRTNRSSVKtPESIVPIAPELQPSTSRNQLvTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTT 1380
Cdd:PHA03247 2570 pprpAPRPSEPAVTSRARRPDAP-PQSARPRAPVDDRGDPRGPA-PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1381 STDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEP-FTPTDQSVTPEA--IAQGGQSKTLRSSTVRAMPVPTTPEF 1457
Cdd:PHA03247 2648 PPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRaARPTVGSLTSLAdpPPPPPTPEPAPHALVSATPLPPGPAA 2727
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1458 ---QSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLE-PKSQASRNQRWGAVRAAESLTAIPEPASP 1533
Cdd:PHA03247 2728 arqASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAgPPRRLTRPAVASLSESRESLPSPWDPADP 2807
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1534 QLLETPIHASQIQKVEPAGRSRFTPELQPKAS-----------------------QSRKRSLATMDSPPHQKQPQRGEVS 1590
Cdd:PHA03247 2808 PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPppppgppppslplggsvapggdvRRRPPSRSPAAKPAAPARPPVRRLA 2887
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1591 QKTViiKEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALG 1670
Cdd:PHA03247 2888 RPAV--SRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLG 2965
|
....*...
gi 2462611565 1671 GSLAGSAA 1678
Cdd:PHA03247 2966 ALVPGRVA 2973
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
747-1231 |
9.05e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 67.66 E-value: 9.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 747 PPQELGPSHCSFQTTGLLNCKMPPAEKASRIRAAEKVSRgdqeSPDACLPPTVPEAPAPPQKPlnsqsqkhlapppllsp 826
Cdd:PHA03247 2625 DPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR----PRRARRLGRAAQASSPPQRP----------------- 2683
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 827 LLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPS-TSTAQPVTPkptsqaTRS 905
Cdd:PHA03247 2684 RRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVpAGPATPGGP------ARP 2757
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 906 RTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQAT 985
Cdd:PHA03247 2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 986 RGRKNRSSVKTPEP----VVPTAPelqpsTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPK 1061
Cdd:PHA03247 2838 APPPPPGPPPPSLPlggsVAPGGD-----VRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQ 2912
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1062 PTSR-TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPV 1140
Cdd:PHA03247 2913 APPPpQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASS 2992
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1141 TPEPTSRATRGRKNRSSGKTPEtlVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQ-PSTSTD 1219
Cdd:PHA03247 2993 TPPLTGHSLSRVSSWASSLALH--EETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHdPFAHEP 3070
|
490
....*....|..
gi 2462611565 1220 QPVTPEPTSQAT 1231
Cdd:PHA03247 3071 DPATPEAGARES 3082
|
|
| FHA |
pfam00498 |
FHA domain; The FHA (Forkhead-associated) domain is a phosphopeptide binding motif. |
76-131 |
1.20e-10 |
|
FHA domain; The FHA (Forkhead-associated) domain is a phosphopeptide binding motif.
Pssm-ID: 459831 [Multi-domain] Cd Length: 66 Bit Score: 58.74 E-value: 1.20e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462611565 76 VVGRMPDCSVALPFPSISKQHAEIEILAwDKAPILRDCGSLNGT-----QILRPPKVLSPG 131
Cdd:pfam00498 2 TIGRSPDCDIVLDDPSVSRRHAEIRYDG-GGRFYLEDLGSTNGTfvngqRLGPEPVRLKDG 61
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
868-1306 |
3.26e-10 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 64.98 E-value: 3.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 868 KSSRMTPFPATSAAPEPHPSTstaqpvtpKPTSQATRSRTNRSSVKTPEpvvptapelqpSTSTDQPVTSEPTSQVTRGR 947
Cdd:pfam17823 53 KSSEQ*NFCAATAAPAPVTLT--------KGTSAAHLNSTEVTAEHTPH-----------GTDLSEPATREGAADGAASR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 948 ----KSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGrknrSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1023
Cdd:pfam17823 114 alaaAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAA----PRAAIAAASAPHAASPAPRTAASSTTAASSTT 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1024 QATRGrKNRSSVKTPEPVVPTAPELRPSTSTdrpVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKP 1103
Cdd:pfam17823 190 AASSA-PTTAASSAPATLTPARGISTAATAT---GHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVAS 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1104 TSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPeTLVPTAPKLEPSTSTDQPVTP 1183
Cdd:pfam17823 266 AAGTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQAQGPIIQVSTDQPVHNTAGEP-TPSPSNTTLEPNTPKSVASTN 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1184 EPTSQATRGRTNRSSVkTPETVVPTA--PELQPSTSTDQPvTPEPTSQATRGRTdrssvktpetvVPTAPELQASASTDQ 1261
Cdd:pfam17823 345 LAVVTTTKAQAKEPSA-SPVPVLHTSmiPEVEATSPTTQP-SPLLPTQGAAGPG-----------ILLAPEQVATEATAG 411
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 2462611565 1262 PVTSEPTSRTTRGRKnrssvktpetvVPAAPELQPSTS------TDQPVTP 1306
Cdd:pfam17823 412 TASAGPTPRSSGDPK-----------TLAMASCQLSTQgqylvvTTDPLTP 451
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1081-1469 |
1.12e-09 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 63.06 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1081 TVVPTAP-ELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTV-PIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSG 1158
Cdd:pfam17823 63 ATAAPAPvTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAAdGAASRALAAAASSSPSSAAQSLPAAIAALPSEAF 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1159 KTPETLVPTAP-KLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPST--STDQPVTPEPTSQATRGRT 1235
Cdd:pfam17823 143 SAPRAAACRANaSAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSapATLTPARGISTAATATGHP 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1236 DRSSVKTPETVVPTAPELQASASTDQPVTSEPTSrTTRGRKNRSSVKTPETVVPAAPELQPSTST---DQPVTPEPTSRA 1312
Cdd:pfam17823 223 AAGTALAAVGNSSPAAGTVTAAVGTVTPAALATL-AAAAGTVASAAGTINMGDPHARRLSPAKHMpsdTMARNPAAPMGA 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1313 -TRGRTNRSSVKTPesIVPIAPELQPSTSRNQLVTPEPTSRATRCRT--NRSSVKTPEPVVPTAPEPH----PTTSTDQP 1385
Cdd:pfam17823 302 qAQGPIIQVSTDQP--VHNTAGEPTPSPSNTTLEPNTPKSVASTNLAvvTTTKAQAKEPSASPVPVLHtsmiPEVEATSP 379
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1386 VTPKLTSRATRRKTNRSSVKTPKPVEPAAsdlepfTPTDQSVTPEAIAQGGqSKTLRSSTVRampvPTTpEFQSPVTTDQ 1465
Cdd:pfam17823 380 TTQPSPLLPTQGAAGPGILLAPEQVATEA------TAGTASAGPTPRSSGD-PKTLAMASCQ----LST-QGQYLVVTTD 447
|
....
gi 2462611565 1466 PISP 1469
Cdd:pfam17823 448 PLTP 451
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
876-1429 |
1.36e-09 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 63.57 E-value: 1.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 876 PATSAAPEPHPSTSTAQPVTPKPTSQAtrsrtnrssVKTPEPVVPTAPE---LQPSTSTDQPVTSEPTSQVTRGRKSRSS 952
Cdd:PRK10263 339 PVTQTPPVASVDVPPAQPTVAWQPVPG---------PQTGEPVIAPAPEgypQQSQYAQPAVQYNEPLQQPVQPQQPYYA 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 953 VKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGrkNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNR 1032
Cdd:PRK10263 410 PAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAG--NAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQ 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1033 SSVKtPEPVVPTAPELRPSTSTDRPVtpkpTSRTTRSRTNMSS--------VKTPETVVPTAPELqiSTSTDQPVTPKPT 1104
Cdd:PRK10263 488 PVVE-PEPVVEETKPARPPLYYFEEV----EEKRAREREQLAAwyqpipepVKEPEPIKSSLKAP--SVAAVPPVEAAAA 560
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1105 SRTTRSRTNMSSVKNPESTVPIAPELPPSTSTeqpvTPEPTSRATRG----RKNRSSGKTPETLVPTAPKLePStstdQP 1180
Cdd:PRK10263 561 VSPLASGVKKATLATGAAATVAAPVFSLANSG----GPRPQVKEGIGpqlpRPKRIRVPTRRELASYGIKL-PS----QR 631
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1181 VTPEPTSQATRGRTNRSSVKTPETVVPTAPE---LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA 1257
Cdd:PRK10263 632 AAEEKAREAQRNQYDSGDQYNDDEIDAMQQDelaRQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRY 711
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1258 STDQPVTSEPTSRTTRgrkNRSSVKTPETVVPAAPELQPS-----TSTDQPVTPEPTSRATRGRTNRSSVKTPESivPIA 1332
Cdd:PRK10263 712 SGEQPAGANPFSLDDF---EFSPMKALLDDGPHEPLFTPIvepvqQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQ--PVA 786
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1333 PELQPSTSRnQLVTPEPTSRATRcRTNRSSVKTPEPVVPTAPEPhPTTSTDQPVTPKLTSRATRRKTNRSSVKTP--KPV 1410
Cdd:PRK10263 787 PQPQYQQPQ-QPVAPQPQYQQPQ-QPVAPQPQYQQPQQPVAPQP-QYQQPQQPVAPQPQDTLLHPLLMRNGDSRPlhKPT 863
|
570
....*....|....*....
gi 2462611565 1411 EPAASdLEPFTPTDQSVTP 1429
Cdd:PRK10263 864 TPLPS-LDLLTPPPSEVEP 881
|
|
| BRCT_BRC1_like_rpt6 |
cd18439 |
sixth (C-terminal) BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) ... |
1733-1830 |
2.54e-09 |
|
sixth (C-terminal) BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins; Schizosaccharomyces pombe BRC1 is required for mitotic fidelity, specifically in the G2 phase of the cell cycle. It plays a role in chromatin organization. The family also includes Cryptococcus neoformans DNA ligase 4 (LIG4, also known as DNA ligase IV or polydeoxyribonucleotide synthase [ATP] 4), which is involved in dsDNA break repair, and plays a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologus end-joining. Members in this family contains six BRCT domains. This family corresponds to the sixth repeat.
Pssm-ID: 349392 Cd Length: 116 Bit Score: 56.54 E-value: 2.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1733 EKNFGFSLQDALSRARERR--LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKP--------QRVVITCPQD 1802
Cdd:cd18439 1 EKKYGCTLAESLARAKANKgkLLKGYTVYLTPKVKGGVETFKSIVEANGGICNLLRAAKGKLgdgiaekgPVVLISTTKE 80
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2462611565 1803 ------------FPHCSIPLRvglpllSPEFLLTGVLKQE 1830
Cdd:cd18439 81 kklwpkflknarEGGKEPRVY------STDWLLDVVLRQE 114
|
|
| BRCT |
cd00027 |
C-terminal domain of the breast cancer suppressor protein (BRCA1) and related domains; The ... |
1650-1713 |
1.63e-08 |
|
C-terminal domain of the breast cancer suppressor protein (BRCA1) and related domains; The BRCT (BRCA1 C-terminus) domain is found within many DNA damage repair and cell cycle checkpoint proteins. BRCT domains interact with each other forming homo/hetero BRCT multimers, but are also involved in BRCT-non-BRCT interactions and interactions within DNA strand breaks. BRCT tandem repeats bind to phosphopeptides; it has been shown that the repeats in human BRCA1 bind specifically to pS-X-X-F motifs, mediating the interaction between BRCA1 and the DNA helicase BACH1, or BRCA1 and CtIP, a transcriptional corepressor. It is assumed that BRCT repeats play similar roles in many signaling pathways associated with the response to DNA damage.
Pssm-ID: 349339 [Multi-domain] Cd Length: 68 Bit Score: 52.75 E-value: 1.63e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462611565 1650 PKVLFTGVVDARGE---RAVLALGGSLAGS-AAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQS 1713
Cdd:cd00027 1 LVICFSGLDDEEREelkKLIEALGGKVSESlSSKVTHLIAKSPSGEKYYLAALAWGIPIVSPEWLLDC 68
|
|
| FHA |
smart00240 |
Forkhead associated domain; Found in eukaryotic and prokaryotic proteins. Putative nuclear ... |
76-121 |
2.84e-08 |
|
Forkhead associated domain; Found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain.
Pssm-ID: 214578 [Multi-domain] Cd Length: 52 Bit Score: 51.41 E-value: 2.84e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 2462611565 76 VVGRMP-DCSVALPFPSISKQHAEIEILAWDKApILRDCGSLNGTQI 121
Cdd:smart00240 2 TIGRSSeDCDIQLDGPSISRRHAVIVYDGGGRF-YLIDLGSTNGTFV 47
|
|
| BRCT_TopBP1_rpt7 |
cd17738 |
seventh BRCT domain of DNA topoisomerase 2-binding protein 1; TopBP1, also termed DNA ... |
1650-1717 |
1.04e-07 |
|
seventh BRCT domain of DNA topoisomerase 2-binding protein 1; TopBP1, also termed DNA topoisomerase II-beta-binding protein 1, or DNA topoisomerase II-binding protein 1, functions in DNA replication and damage response. It binds double-stranded DNA breaks and nicks as well as single-stranded DNA. TopBP1 contains six copies of BRCT domain. The family corresponds to the seventh BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is missing in this group.
Pssm-ID: 349370 [Multi-domain] Cd Length: 75 Bit Score: 50.64 E-value: 1.04e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462611565 1650 PKVLFTGVVDArgERA-----VLALGGSLAGSA---AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1717
Cdd:cd17738 2 PVFLLSGFSED--EKKelisiIEKLGGKVLDSDefdPKCTHLICGKPSRSEKFLAACAAGKWILHPSYIEASAKAG 75
|
|
| FHA_DgcB-like |
cd22682 |
forkhead associated (FHA) domain found in Bdellovibrio bacteriovorus GGDEF domain protein DgcB ... |
59-152 |
1.15e-07 |
|
forkhead associated (FHA) domain found in Bdellovibrio bacteriovorus GGDEF domain protein DgcB and similar proteins; DgcB is a GGDEF enzyme that produces cyclic-di-GMP in response to an unknown stimulus. It appends the C-terminal GGDEF enzymatic domain with an N-terminal forkhead-associated (FHA) domain that acts as a consensus phosphopeptide sensor. The GGDEF and sensory FHA domains form an asymmetrical dimer.
Pssm-ID: 438734 [Multi-domain] Cd Length: 96 Bit Score: 51.37 E-value: 1.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 59 SGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAwdKAPILRDCGSLNGTQIlrPPKVLSPGVSHRLRD 138
Cdd:cd22682 6 IGPPGVGKQFPITESTIVIGRSVESQVQIDDDSVSRYHAKLAVNP--SAVSIIDLGSTNGTIV--NGKKIPKLASCDLQN 81
|
90
....*....|....
gi 2462611565 139 QELILFADLLCQYH 152
Cdd:cd22682 82 GDQIKIGNTIFKFH 95
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
1078-1381 |
1.20e-07 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 56.93 E-value: 1.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1078 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPeSTVPIAPELPPSTSTEQPV---TPEPTSRATRGRKN 1154
Cdd:TIGR00927 103 TPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTP-ATPSRALNHYISTSGRQRVksyTPKPRGEVKSSSPT 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1155 RSSGK----TPETLVPTAPKLEPSTSTDQPvtpeptsqATRGRTNRSSVKTPETvvpTAPELQPSTSTDQPVTPEPTSQA 1230
Cdd:TIGR00927 182 QTREKvrkyTPSPLGRMVNSYAPSTFMTMP--------RSHGITPRTTVKDSEI---TATYKMLETNPSKRTAGKTTPTP 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1231 TRGRTDRSS---VKTPETVVPTAPELQASAST-DQPVTSEPTSRTT-RGRKNRSSVKTPETVV----PAAPELQPSTSTD 1301
Cdd:TIGR00927 251 LKGMTDNTPtflTREVETDLLTSPRSVVEKNTlTTPRRVESNSSTNhWGLVGKNNLTTPQGTVlehtPATSEGQVTISIM 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1302 QPVTPEPTSRATRGRTNRS-SVKTPESIVPIAP------ELQPSTSRNQLVTPE----PTSRATRCrtnrsSVKTPEPVV 1370
Cdd:TIGR00927 331 TGSSPAETKASTAAWKIRNpLSRTSAPAVRIASatfrglEKNPSTAPSTPATPRvravLTTQVHHC-----VVVKPAPAV 405
|
330
....*....|.
gi 2462611565 1371 PTAPEPHPTTS 1381
Cdd:TIGR00927 406 PTTPSPSLTTA 416
|
|
| BRCT_microcephalin_rpt2 |
cd17736 |
second BRCT domain of microcephalin and similar proteins; Microcephalin is a DNA damage ... |
1652-1720 |
1.31e-07 |
|
second BRCT domain of microcephalin and similar proteins; Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. It has been implicated in chromosome condensation and DNA damage induced cellular responses. It may play a role in neurogenesis and regulation of the size of the cerebral cortex. Microcephalin contains three BRCT repeats. This family corresponds to the second repeat.
Pssm-ID: 349368 [Multi-domain] Cd Length: 76 Bit Score: 50.67 E-value: 1.31e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462611565 1652 VLFTGVVDARGE---RAVLALGG-SLAGSAAE-ASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1720
Cdd:cd17736 3 LVMTSVHSEEQElleSVVKKLGGfRVEDSVTEkTTHVVVGSPRRTLNVLLGIARGCWILSPDWVLESLEAGKWL 76
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1028-1436 |
1.36e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 57.10 E-value: 1.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1028 GRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRT 1107
Cdd:PHA03307 38 GSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPP 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1108 TRSrtnMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRgrknrSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTS 1187
Cdd:PHA03307 118 PPT---PPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGA-----SPAAVASDAASSRQAALPLSSPEETARAPSSP 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1188 QATRGrTNRSSVKTPETVVPTAPELQPSTSTDQPVtPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1267
Cdd:PHA03307 190 PAEPP-PSTPPAAASPRPPRRSSPISASASSPAPA-PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPT 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1268 TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRatrgRTNRSSVKTPESIVPIAPELQPSTSRNQLVTP 1347
Cdd:PHA03307 268 RIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSS----PRASSSSSSSRESSSSSTSSSSESSRGAAVSP 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1348 EPTSRATRCRTNRSSVKTPEPVvPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPvEPAASDLEPFTPTDQSV 1427
Cdd:PHA03307 344 GPSPSRSPSPSRPPPPADPSSP-RKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDAT-GRFPAGRPRPSPLDAGA 421
|
....*....
gi 2462611565 1428 TPEAIAQGG 1436
Cdd:PHA03307 422 ASGAFYARY 430
|
|
| BRCT_nibrin |
cd17741 |
BRCT domain of nibrin and similar proteins; Nibrin (NBN), also termed Nijmegen breakage ... |
1665-1716 |
1.47e-07 |
|
BRCT domain of nibrin and similar proteins; Nibrin (NBN), also termed Nijmegen breakage syndrome protein 1 (NBS1), or cell cycle regulatory protein p95, is a novel DNA double-strand break repair protein that is mutated in Nijmegen breakage syndrome. It is a component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The BRCT (Breast Cancer Suppressor Protein BRCA1, carboxy-terminal) domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo/hetero BRCT multimers, BRCT-non-BRCT interactions, and interactions within DNA strand breaks. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is absent in this group.
Pssm-ID: 349372 [Multi-domain] Cd Length: 74 Bit Score: 50.29 E-value: 1.47e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 2462611565 1665 AVLALGGSLAGSAAEAS-HLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKA 1716
Cdd:cd17741 21 IIAKLGGKVVNEWTEECtHLVMSKIKVTVKVICALISGKPIVTPEYLDALLEA 73
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
975-1524 |
1.78e-07 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 56.63 E-value: 1.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 975 PVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSeptYQATRGrknrssVKTPEPVVPTAPELRPstst 1054
Cdd:PRK10263 315 PITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVA---WQPVPG------PQTGEPVIAPAPEGYP---- 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1055 drpvtPKPTSRTTRSRTNMSSVKtpetvvPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPST 1134
Cdd:PRK10263 382 -----QQSQYAQPAVQYNEPLQQ------PVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAE 450
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1135 STEQPVTPEPTSRATrgrknrssgKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPT-APELQ 1213
Cdd:PRK10263 451 EQQSTFAPQSTYQTE---------QTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKrARERE 521
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1214 PSTSTDQPVtPEPtsqatrgrtdrssVKTPETVVPTAPELQASASTdqPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPE 1293
Cdd:PRK10263 522 QLAAWYQPI-PEP-------------VKEPEPIKSSLKAPSVAAVP--PVEAAAAVSPLASGVKKATLATGAAATVAAPV 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1294 LQPSTSTdqpvTPEPTSRATRG----RTNRSSVKTPESIVPIAPELqPStsrnQLVTPEPTSRATRCRTNRSSVKTPEPV 1369
Cdd:PRK10263 586 FSLANSG----GPRPQVKEGIGpqlpRPKRIRVPTRRELASYGIKL-PS----QRAAEEKAREAQRNQYDSGDQYNDDEI 656
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1370 VPTAPE----------------------PHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQ-- 1425
Cdd:PRK10263 657 DAMQQDelarqfaqtqqqrygeqyqhdvPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKAll 736
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1426 -----------SVTPEAIAQgGQSKTLRSSTVRAMPVPTTPEFQSPvttDQPISPEPITQ--PSCIKRQRAAGNPGSLAA 1492
Cdd:PRK10263 737 ddgpheplftpIVEPVQQPQ-QPVAPQQQYQQPQQPVAPQPQYQQP---QQPVAPQPQYQqpQQPVAPQPQYQQPQQPVA 812
|
570 580 590
....*....|....*....|....*....|...
gi 2462611565 1493 P-IDHKPCSAPLEPKSQASRNQRWGAVRAAESL 1524
Cdd:PRK10263 813 PqPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTL 845
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
773-1133 |
2.18e-07 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 56.24 E-value: 2.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 773 KASRIRAAEKVSRG--DQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKT----RQDGSQEA 846
Cdd:PTZ00449 568 KPSKIPTLSKKPEFpkDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRppppQRPSSPER 647
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 847 PEAPLS--SELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPe 924
Cdd:PTZ00449 648 PEGPKIikSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLP- 726
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 925 lqpstsTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTsqatrgRKNRSSVKTPEPVVPTA 1004
Cdd:PTZ00449 727 ------RDEEFPFEPIGDPDAEQPDDIEFFTPPEEERTFFHETPADTPLPDILAEEF------KEEDIHAETGEPDEAMK 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1005 PELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEpvVPTAPELRPSTSTDRPVTPKptsrTTRSRTNMSSVKTPETVVP 1084
Cdd:PTZ00449 795 RPDSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTD--LESDAGRIAKDASGKIVKLK----RSKSFDDLTTVEEAEEMGA 868
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 2462611565 1085 TAPELQIS---TSTD----QPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPS 1133
Cdd:PTZ00449 869 EARKIVVDddgTEADdedtHPPEEKHKSEVRRRRPPKKPSKPKKPSKPKKPKKPDS 924
|
|
| RTT107_BRCT_5 |
pfam16770 |
Regulator of Ty1 transposition protein 107 BRCT domain; This is the fifth BRCT domain of ... |
1669-1725 |
6.70e-07 |
|
Regulator of Ty1 transposition protein 107 BRCT domain; This is the fifth BRCT domain of regulator of Ty1 transposition protein 107 (RTT107). It is involved in binding phosphorylated histone H2A.
Pssm-ID: 465266 Cd Length: 91 Bit Score: 49.05 E-value: 6.70e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462611565 1669 LGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEY 1725
Cdd:pfam16770 33 LGIKIVQDPSKCNHLIAPKILRTEKFLCALAFAPYILSPDFITDCLKEGKLPDEEDY 89
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1131-1539 |
8.03e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 54.41 E-value: 8.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1131 PPSTSTEQPVTPeptsraTRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAP 1210
Cdd:PHA03307 24 PPATPGDAADDL------LSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1211 ELQPSTSTDQPVTPEPTSqaTRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPA 1290
Cdd:PHA03307 98 ASPAREGSPTPPGPSSPD--PPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1291 APELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPvv 1370
Cdd:PHA03307 176 LSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPEN-- 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1371 pTAPEPHPTTST-----DQPVTPKLTSRATRRKTNRSSV--KTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRS 1443
Cdd:PHA03307 254 -ECPLPRPAPITlptriWEASGWNGPSSRPGPASSSSSPreRSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSS 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1444 S-TVRAMPVPTTPEFQSPVTTDQPisPEPITQPSCIKRQRAAGNPGSLAAPIDHKPC----SAPLEPKSQASRNQRWGAV 1518
Cdd:PHA03307 333 SeSSRGAAVSPGPSPSRSPSPSRP--PPPADPSSPRKRPRPSRAPSSPAASAGRPTRrrarAAVAGRARRRDATGRFPAG 410
|
410 420
....*....|....*....|.
gi 2462611565 1519 RAAESLTAIPEPASPQLLETP 1539
Cdd:PHA03307 411 RPRPSPLDAGAASGAFYARYP 431
|
|
| FHA_Ki67 |
cd22673 |
forkhead associated (FHA) domain found in proliferation marker protein Ki-67 and similar ... |
53-146 |
9.42e-07 |
|
forkhead associated (FHA) domain found in proliferation marker protein Ki-67 and similar proteins; Ki-67, also called antigen identified by monoclonal antibody Ki-67, antigen KI-67, or antigen Ki67, acts as a biological surfactant to disperse mitotic chromosomes. It is required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Ki-67 binds DNA with a preference for supercoiled DNA and AT-rich DNA. It may also play a role in chromatin organization. Ki-67 contains an FHA domain at its N-terminus. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438725 [Multi-domain] Cd Length: 95 Bit Score: 48.75 E-value: 9.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 53 GRLHIF--SGAHGPEkdFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKApILRDCGSLNGTQiLRPPKVLSP 130
Cdd:cd22673 1 GKLVVIkkDGTDGSR--FPLTKKSCTFGRDLSCDIRIQLPGVSREHCRIEVDENGKA-YLENLSTTNPTL-VNGKAIEKS 76
|
90
....*....|....*.
gi 2462611565 131 gvsHRLRDQELILFAD 146
Cdd:cd22673 77 ---AELKDGDVITIGG 89
|
|
| FHA_FhaA-like |
cd22668 |
forkhead associated (FHA) domain found in Mycobacterium tuberculosis FHA domain-containing ... |
62-121 |
1.53e-06 |
|
forkhead associated (FHA) domain found in Mycobacterium tuberculosis FHA domain-containing protein FhaA and similar proteins; FhaA regulates cell growth and peptidoglycan synthesis by binding to MviN. It may inhibit the late stages of peptidoglycan synthesis. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438720 [Multi-domain] Cd Length: 91 Bit Score: 47.85 E-value: 1.53e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462611565 62 HGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIeilAWD-KAPILRDCGSLNGTQI 121
Cdd:cd22668 7 DGSGRVYQLREGSNIIGRGSDADFRLPDTGVSRRHAEI---RWDgQVAHLTDLGSTNGTTV 64
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1015-1595 |
1.71e-06 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 53.17 E-value: 1.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1015 QPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTsrttrsrtnMSSVKTPETVVPTAPElqisTS 1094
Cdd:PRK10263 314 APITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQP---------VPGPQTGEPVIAPAPE----GY 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1095 TDQPVTPKPTSRttrsrtnmssvKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPS 1174
Cdd:PRK10263 381 PQQSQYAQPAVQ-----------YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1175 TSTDQPVTPEPTSQATRgrtnrssvKTPETVVPTAPELQPStSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPT-APEL 1253
Cdd:PRK10263 450 EEQQSTFAPQSTYQTEQ--------TYQQPAAQEPLYQQPQ-PVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKrARER 520
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1254 QASASTDQPVtSEPtsrttrgrknrssVKTPETVVPAAPelQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAP 1333
Cdd:PRK10263 521 EQLAAWYQPI-PEP-------------VKEPEPIKSSLK--APSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAP 584
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1334 ELQPSTSRnqlvTPEPtsratrcrtnrssvKTPEPVVPTAPEPH----PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKP 1409
Cdd:PRK10263 585 VFSLANSG----GPRP--------------QVKEGIGPQLPRPKrirvPTRRELASYGIKLPSQRAAEEKAREAQRNQYD 646
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1410 VEPAASDLEpftpTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEfqspvTTDQPISPEPITQPSCIKRQRAAG---- 1485
Cdd:PRK10263 647 SGDQYNDDE----IDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAE-----DADAAAEAELARQFAQTQQQRYSGeqpa 717
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1486 --NPGSLA----APID-------HKPCSAP-LEPKSQASRNQRWGAVRAAESLTAIPEPA--SPQLLETPIHASQIQKVE 1549
Cdd:PRK10263 718 gaNPFSLDdfefSPMKallddgpHEPLFTPiVEPVQQPQQPVAPQQQYQQPQQPVAPQPQyqQPQQPVAPQPQYQQPQQP 797
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 2462611565 1550 PAGRSRFTPELQPKASQSRKRSLATMDSPP---HQKQPQRGEVSQKTVI 1595
Cdd:PRK10263 798 VAPQPQYQQPQQPVAPQPQYQQPQQPVAPQpqyQQPQQPVAPQPQDTLL 846
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
928-1286 |
2.10e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 52.87 E-value: 2.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 928 STSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEP----VVPT 1003
Cdd:PHA03307 61 ACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPdlseMLRP 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1004 APELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRtnmssvktpetvv 1083
Cdd:PHA03307 141 VGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPP------------- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1084 PTAPELQISTSTDQPVTPKpTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPET 1163
Cdd:PHA03307 208 RRSSPISASASSPAPAPGR-SAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPAS 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1164 LVPTAPKLEPSTSTDQPVTPEPTSQAT--RGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVK 1241
Cdd:PHA03307 287 SSSSPRERSPSPSPSSPGSGPAPSSPRasSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPR 366
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 2462611565 1242 TPETVVPTAPELQASAST-----------DQPVTSEPTSRTTRGRKNRSSVKTPET 1286
Cdd:PHA03307 367 KRPRPSRAPSSPAASAGRptrrraraavaGRARRRDATGRFPAGRPRPSPLDAGAA 422
|
|
| FHA_PP2C70-like |
cd22678 |
forkhead associated (FHA) domain found in Arabidopsis thaliana protein phosphatase 2C 70 ... |
77-143 |
3.97e-06 |
|
forkhead associated (FHA) domain found in Arabidopsis thaliana protein phosphatase 2C 70 (AtPP2C70) and similar proteins; AtPP2C70, also called kinase-associated protein phosphatase, or protein ROOT ATTENUATED GROWTH 1, dephosphorylates the serine/threonine receptor-like kinase RLK5. It may function as a signaling component in a pathway involving RLK5. It acts as a negative regulator of the CLAVATA1 signaling in plant development by binding and dephosphorylating CLAVATA1. It is also a component of a signaling pathway which mediates adaptation to NaCl stress. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438730 [Multi-domain] Cd Length: 102 Bit Score: 46.97 E-value: 3.97e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462611565 77 VGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQI-LRPPKVlsPGVSHRLRDQELIL 143
Cdd:cd22678 27 IGRIQRGDIALKDDEVSGKHARIEWNSTGSKWELVDLGSLNGTLVnGESISP--NGRPVVLSSGDVIT 92
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
796-1170 |
4.18e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 52.00 E-value: 4.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 796 PPTVPEAPA-PPQKPLNSQSQ-KHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAP-------EAPLSSEL-----EPFHPK 861
Cdd:PTZ00449 510 PPEGPEASGlPPKAPGDKEGEeGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPakehkpsKIPTLSKKpefpkDPKHPK 589
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 862 PKIRTRKSSRmtpfPATSAAPEPHPSTSTAQPVT-PKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTS-EP 939
Cdd:PTZ00449 590 DPEEPKKPKR----PRSAQRPTRPKSPKLPELLDiPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSpKP 665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 940 TSQVTRGRK-----SRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGR-------KNRSSVKTPePVVPTAPEL 1007
Cdd:PTZ00449 666 PFDPKFKEKfyddyLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRplppklpRDEEFPFEP-IGDPDAEQP 744
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1008 QPSTSTDQPVTSEPTYQATRGRKNRSSV-----KTP----EPVVPTAPELRPSTST---DRPVTPKPTSRTTRSRTNMSS 1075
Cdd:PTZ00449 745 DDIEFFTPPEEERTFFHETPADTPLPDIlaeefKEEdihaETGEPDEAMKRPDSPSeheDKPPGDHPSLPKKRHRLDGLA 824
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1076 VKTPEtvVPTAPELQISTSTDQPVTPKptsrttRSRTNmssvkNPESTVPIAPELPPSTS--------TE------QPVT 1141
Cdd:PTZ00449 825 LSTTD--LESDAGRIAKDASGKIVKLK------RSKSF-----DDLTTVEEAEEMGAEARkivvdddgTEaddedtHPPE 891
|
410 420
....*....|....*....|....*....
gi 2462611565 1142 PEPTSRATRGRKNRSSGKTPETLVPTAPK 1170
Cdd:PTZ00449 892 EKHKSEVRRRRPPKKPSKPKKPSKPKKPK 920
|
|
| FHA_Kanadaptin |
cd22677 |
forkhead associated (FHA) domain found in kanadaptin and similar proteins; Kanadaptin, also ... |
76-137 |
5.34e-06 |
|
forkhead associated (FHA) domain found in kanadaptin and similar proteins; Kanadaptin, also called human lung cancer oncogene 3 protein (HLC-3), kidney anion exchanger adapter protein, or solute carrier family 4 anion exchanger member 1 adapter protein (SLC4A1AP), is a nuclear protein widely expressed in mammalian tissues. It was originally isolated as a kidney Cl-/HCO3- anion exchanger 1 (kAE1)-binding protein. It is a highly mobile nucleocytoplasmic shuttling and multilocalizing protein. Its role in mammalian cells remains unclear. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438729 [Multi-domain] Cd Length: 106 Bit Score: 46.78 E-value: 5.34e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462611565 76 VVGRMPDCSVALPFPSISKQHAeieILAWDKAPI-------LRDCGSLNGTQILRPPkvLSPGVSHRLR 137
Cdd:cd22677 25 VFGRLPGCDVVLEHPSISRYHA---VLQYRGDADdhdggfyLYDLGSTHGTFLNKQR--IPPKQYYRLR 88
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
890-1116 |
5.58e-06 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 50.96 E-value: 5.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 890 TAQPVTPKP-------TSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRS-SVKTPETVVP 961
Cdd:PRK13914 144 TSTPVAPTQevkkettTQQAAPAAETKTEVKQTTQATTPAPKVAETKETPVVDQNATTHAVKSGDTIWAlSVKYGVSVQD 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 962 TALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVP--TAPELQPSTSTDQPVTSeptyqatrgrknRSSVKTPE 1039
Cdd:PRK13914 224 IMSWNNLSSSSIYVGQKLAIKQTANTATPKAEVKTEAPAAEkqAAPVVKENTNTNTATTE------------KKETTTQQ 291
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462611565 1040 PVVPTAPelrpsTSTDRPvTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS 1116
Cdd:PRK13914 292 QTAPKAP-----TEAAKP-APAPSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGSSNNNS 362
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1204-1507 |
6.69e-06 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 50.73 E-value: 6.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1204 TVVPTAP-ELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPE-TVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSV 1281
Cdd:pfam17823 63 ATAAPAPvTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREgAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAF 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1282 KTPETVVPAAP-ELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNR 1360
Cdd:pfam17823 143 SAPRAAACRANaSAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHP 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1361 SSVKTPEPVVPTAPEPHPTTSTDQPVTP-KLTSRATRRKTNRSSVKTPKPVEPAASDLEP--FTPTDQSVTPEAIAQGGQ 1437
Cdd:pfam17823 223 AAGTALAAVGNSSPAAGTVTAAVGTVTPaALATLAAAAGTVASAAGTINMGDPHARRLSPakHMPSDTMARNPAAPMGAQ 302
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462611565 1438 SKTLRSSTVRAMPVPTT---PEFQSPVTTDQPISPEPITQPS---CIKRQRAAGNPGSLAAPIDHKPCSAPLEPKS 1507
Cdd:pfam17823 303 AQGPIIQVSTDQPVHNTagePTPSPSNTTLEPNTPKSVASTNlavVTTTKAQAKEPSASPVPVLHTSMIPEVEATS 378
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
999-1433 |
7.18e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 51.23 E-value: 7.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 999 PVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAP----ELRPS---TSTDRPVTPKPTsrttrsrt 1071
Cdd:PTZ00449 514 PEASGLPPKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPgpakEHKPSkipTLSKKPEFPKDP-------- 585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1072 nmssvKTPETvvPTAPElqistSTDQPVTP-KPTSRttrsrtnmSSVKNPEST-VPIAPELPPSTSTeqPVTPEPTSRAT 1149
Cdd:PTZ00449 586 -----KHPKD--PEEPK-----KPKRPRSAqRPTRP--------KSPKLPELLdIPKSPKRPESPKS--PKRPPPPQRPS 643
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1150 RGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSq 1229
Cdd:PTZ00449 644 SPERPEGPKIIKSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLP- 722
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1230 ATRGRTDRSSVKTPETvvPTAPElqasaSTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPept 1309
Cdd:PTZ00449 723 PKLPRDEEFPFEPIGD--PDAEQ-----PDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEEDIHAETGEPDEA--- 792
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1310 srATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATR---------CRTNRSSVKTPEPVVPTAPEPHP-- 1378
Cdd:PTZ00449 793 --MKRPDSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTDLESDAGRiakdasgkiVKLKRSKSFDDLTTVEEAEEMGAea 870
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462611565 1379 ---------TTSTDQPVTP---KLTSRATRRKTNRSSVKTPKPVEPAasdlEPFTPtDQSVTPEAIA 1433
Cdd:PTZ00449 871 rkivvdddgTEADDEDTHPpeeKHKSEVRRRRPPKKPSKPKKPSKPK----KPKKP-DSAFIPSIIA 932
|
|
| BRCT_p53bp1_rpt1 |
cd17745 |
first (central) BRCT domain in p53-binding protein 1 (p53BP1) and similar proteins; p53BP1, ... |
1683-1717 |
7.62e-06 |
|
first (central) BRCT domain in p53-binding protein 1 (p53BP1) and similar proteins; p53BP1, also termed 53BP1, or TP53-binding protein 1 (TP53BP1) , is a double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. TP53BP1 contains two tandem BRCT repeats. This family also includes Schizosaccharomyces pombe Crb2, which is a checkpoint mediator required for the cellular response to DNA damage. This model corresponds to the first BRCT domain.
Pssm-ID: 349376 [Multi-domain] Cd Length: 99 Bit Score: 46.15 E-value: 7.62e-06
10 20 30
....*....|....*....|....*....|....*
gi 2462611565 1683 LVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1717
Cdd:cd17745 64 LIADSPSRTPKYLQALALGIPCVSHKWILDCIEAG 98
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
1172-1299 |
7.74e-06 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 51.25 E-value: 7.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1172 EPSTSTDQPVTPEPTSQATrgrtnrssvkTPETVVPTAPELQPSTsTDQPVTPEPTSQATRGrTDRSSVKTPETVVPTAP 1251
Cdd:NF033875 49 QPGTTTVQPDNPDPQSGSE----------TPKTAVSEEATVQKDT-TSQPTKVEEVASEKNG-AEQSSATPNDTTNAQQP 116
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2462611565 1252 ELQASAST-DQPVTSEPTSRTTRGRknrssvktPETVVPAAPELQPSTS 1299
Cdd:NF033875 117 TVGAEKSAqEQPVVSPETTNEPLGQ--------PTEVAPAENEANKSTS 157
|
|
| FHA_PS1-like |
cd22691 |
forkhead associated (FHA) domain found in Arabidopsis thaliana Protein PARALLEL SPINDLE 1 (PS1) ... |
76-119 |
9.15e-06 |
|
forkhead associated (FHA) domain found in Arabidopsis thaliana Protein PARALLEL SPINDLE 1 (PS1) and similar proteins; PS1 is an FHA domain-containing protein required for normal spindle orientation at male meiosis II and normal formation of tetrad of microspores. It is not involved in female meiosis. Mutations in PS1 lead to the production of diploid pollen grains. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438743 [Multi-domain] Cd Length: 113 Bit Score: 46.26 E-value: 9.15e-06
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 2462611565 76 VVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGT 119
Cdd:cd22691 32 VVGRHPDCDIVLDHPSISRFHLEIRIIPSRRKITLTDLSSVHGT 75
|
|
| FHA_ArnA-like |
cd22680 |
forkhead associated (FHA) domain found in Sulfolobus Acidocaldarius FHA domain-containing ... |
55-131 |
1.24e-05 |
|
forkhead associated (FHA) domain found in Sulfolobus Acidocaldarius FHA domain-containing protein ArnA and similar proteins; ArnA is an FHA domain-containing protein from Sulfolobus acidocaldarius that was shown to strongly interact with ArnB, a von Willebrand domain-containing protein. They act synergistically and negatively to modulate motility. ArnA is involved in regulating archaella expression in S. acidocaldarius. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438732 [Multi-domain] Cd Length: 96 Bit Score: 45.41 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 55 LHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQI-----LRPPKVLS 129
Cdd:cd22680 3 LEILSSPNLTGKKFPFDFSSVSIGRDPENVIVIPDPFVSRNHARITVD--SNEIYIEDLGSTNGTFVndfkrIKGPAKLH 80
|
..
gi 2462611565 130 PG 131
Cdd:cd22680 81 PN 82
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
946-1314 |
1.67e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.17 E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 946 GRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTyqA 1025
Cdd:PHA03307 38 GSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSP--D 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1026 TRGRKNRSSVKTPEPVVPTAPELR---PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPElqistSTDQPVTPK 1102
Cdd:PHA03307 116 PPPPTPPPASPPPSPAPDLSEMLRpvgSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEE-----TARAPSSPP 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1103 PTSRTTRSRTNMSSVKNPEStVPIAPELPPSTSTeqpvtPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVT 1182
Cdd:PHA03307 191 AEPPPSTPPAAASPRPPRRS-SPISASASSPAPA-----PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPIT 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1183 PEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQAtrgRTDRSSVKTPETVvpTAPELQASASTDQP 1262
Cdd:PHA03307 265 LPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP---RASSSSSSSRESS--SSSTSSSSESSRGA 339
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 2462611565 1263 VTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATR 1314
Cdd:PHA03307 340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
778-1161 |
1.71e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.17 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 778 RAAEKVSRGDQESPDACLPPTVPEAPAP-PQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELE 856
Cdd:PHA03307 46 DSAELAAVTVVAGAAACDRFEPPTGPPPgPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPAS 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 857 PFHPkpkirtrkssrmTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTdqPVT 936
Cdd:PHA03307 126 PPPS------------PAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSS--PPA 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 937 SEPTSQVTRGRKSRSSVKTPetvvptalELQPSTSTDRPVtSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQP 1016
Cdd:PHA03307 192 EPPPSTPPAAASPRPPRRSS--------PISASASSPAPA-PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1017 VTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRttrsRTNMSSVKTPETVVPTAPELQISTSTD 1096
Cdd:PHA03307 263 ITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSS----PRASSSSSSSRESSSSSTSSSSESSRG 338
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462611565 1097 QPVTPKPTSRT--TRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTP 1161
Cdd:PHA03307 339 AAVSPGPSPSRspSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATG 405
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
843-1189 |
1.74e-05 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 49.99 E-value: 1.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 843 SQEAPEAPLSSELEPFHPKPkirTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPePVVPTA 922
Cdd:TIGR00927 76 SSDPPKSSSEMEGEMLAPQA---TVGRDEATPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTP-ATPSRA 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 923 PELQPSTSTDQPVTSepTSQVTRG-RKSRSSVKTPETVvptalelqpststdRPVTSEPtsqatRGRKNRSSVKTPEPVV 1001
Cdd:TIGR00927 152 LNHYISTSGRQRVKS--YTPKPRGeVKSSSPTQTREKV--------------RKYTPSP-----LGRMVNSYAPSTFMTM 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1002 PTAPELQP-STSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTD---------RPVTPKPTSRTTRSRT 1071
Cdd:TIGR00927 211 PRSHGITPrTTVKDSEITATYKMLETNPSKRTAGKTTPTPLKGMTDNTPTFLTREvetdlltspRSVVEKNTLTTPRRVE 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1072 NMSS-----------VKTPETVV----PTAPELQISTSTDQPVTPKptsrTTRSRTNMSSVKNPES-----TVPIAP--- 1128
Cdd:TIGR00927 291 SNSStnhwglvgknnLTTPQGTVlehtPATSEGQVTISIMTGSSPA----ETKASTAAWKIRNPLSrtsapAVRIASatf 366
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462611565 1129 ---ELPPSTSTEQPVTPEPTSRATRgRKNRSSGKTPETLVPTAPklEPS-TSTDQPVTPEPTSQA 1189
Cdd:TIGR00927 367 rglEKNPSTAPSTPATPRVRAVLTT-QVHHCVVVKPAPAVPTTP--SPSlTTALFPEAPSPSPSA 428
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
869-1176 |
2.99e-05 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 48.84 E-value: 2.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 869 SSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPStSTDQPVTSEPTSQVTRGRK 948
Cdd:PHA03369 349 KTASLTAPSRVLAAAAKVAVIAAPQTHTGPADRQRPQRPDGIPYSVPARSPMTAYPPVPQ-FCGDPGLVSPYNPQSPGTS 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 949 SRSSVKTPETVVPTALELQPSTSTDRPVTSEPT-SQATRGRKNRSSVKtpEPVVPTAPELQPSTSTDQPVTSEPTYQATR 1027
Cdd:PHA03369 428 YGPEPVGPVPPQPTNPYVMPISMANMVYPGHPQeHGHERKRKRGGELK--EELIETLKLVKKLKEEQESLAKELEATAHK 505
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1028 GRKNRSS--------VKTPEPVV---PTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVP----TAPELQIS 1092
Cdd:PHA03369 506 SEIKKIAesefknagAKTAAANIepnCSADAAAPATKRARPETKTELEAVVRFPYQIRNMESPAFVHSftstTLAAAAGQ 585
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1093 TSTDQPVTPKPTSRTTrsrTNMSSVKNPESTVpiAPELPPSTSTEQPvTPEPTSRATRGRKNRSSGKTpETLVPTAPKLE 1172
Cdd:PHA03369 586 GSDTAEALAGAIETLL---TQASAQPAGLSLP--APAVPVNASTPAS-TPPPLAPQEPPQPGTSAPSL-ETSLPQQKPVL 658
|
....
gi 2462611565 1173 PSTS 1176
Cdd:PHA03369 659 SKGA 662
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
876-1321 |
3.14e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.83 E-value: 3.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 876 PATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSsvkt 955
Cdd:PRK07764 390 GAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ---- 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 956 petvvPTALELQPSTSTDRPVTSEPTSQATrgrknrssvkTPEPVVPTAPELQPSTSTDQPVTSE-PTYQATRGRKNRSS 1034
Cdd:PRK07764 466 -----PAPAPAAAPEPTAAPAPAPPAAPAP----------AAAPAAPAAPAAPAGADDAATLRERwPEILAAVPKRSRKT 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1035 --VKTPEPVVPtapELRPSTSTdrpvtpkPTSRTTRSRTNMSSVKTPETVVpTApelqISTSTDQPVTPKPTSRTTRSRT 1112
Cdd:PRK07764 531 waILLPEATVL---GVRGDTLV-------LGFSTGGLARRFASPGNAEVLV-TA----LAEELGGDWQVEAVVGPAPGAA 595
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1113 NMSSVKNPESTVPI--APELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQAT 1190
Cdd:PRK07764 596 GGEGPPAPASSGPPeeAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG 675
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1191 RGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPePTSQATRGRTDRSSVKTpetvvpTAPELQASASTDQPVTSEPTSR 1270
Cdd:PRK07764 676 AAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATP-PAGQADDPAAQPPQAAQ------GASAPSPAADDPVPLPPEPDDP 748
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 2462611565 1271 TTRGRKNRSSVKTPETVVPAAP--ELQPSTSTDQPVTPEPTSRATRGRTNRSS 1321
Cdd:PRK07764 749 PDPAGAPAQPPPPPAPAPAAAPaaAPPPSPPSEEEEMAEDDAPSMDDEDRRDA 801
|
|
| FHA_MEK1-like |
cd22670 |
forkhead associated (FHA) domain found in Saccharomyces cerevisiae meiosis-specific serine ... |
52-131 |
3.24e-05 |
|
forkhead associated (FHA) domain found in Saccharomyces cerevisiae meiosis-specific serine/threonine-protein kinase MEK1 and similar proteins; MEK1 (EC 2.7.11.1), also known as MRE4, is a meiosis-specific protein kinase required for chromosome synapsis and meiotic recombination. The recruitment and activation of MEK1 require the phosphorylation of the chromosome axis protein Hop1 at Thr318 (pT318), which is necessary for recognition by the MEK1 FHA domain. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438722 [Multi-domain] Cd Length: 105 Bit Score: 44.53 E-value: 3.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 52 VGRLHIFSGAhGPEKDFPLHLGKNV-VGRMPDCSVALPFPSISKQHAEIEILAWDK--API--LRDCgSLNGTQI----- 121
Cdd:cd22670 1 VGKLEVSSPG-STDIVLPIYKNQVItIGRSPSCDIVINDPFVSRTHCRIYSVQFDEssAPLvyVEDL-SSNGTYLngkli 78
|
90
....*....|.
gi 2462611565 122 -LRPPKVLSPG 131
Cdd:cd22670 79 gRNNTVLLSDG 89
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
777-1069 |
8.72e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.86 E-value: 8.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 777 IRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEA--PLSSE 854
Cdd:PHA03307 100 PAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAalPLSSP 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 855 LEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQP---VTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTST 931
Cdd:PHA03307 180 EETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASspaPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPR 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 932 DQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATrgrkNRSSVKTPEPVVPTAPELQPST 1011
Cdd:PHA03307 260 PAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPR----ASSSSSSSRESSSSSTSSSSES 335
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462611565 1012 STDQPVTSEPTYQATRGRKNRSSVKTPEPvVPTAPELRPSTSTDRPVTPKPTSRTTRS 1069
Cdd:PHA03307 336 SRGAAVSPGPSPSRSPSPSRPPPPADPSS-PRKRPRPSRAPSSPAASAGRPTRRRARA 392
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
1127-1418 |
2.34e-04 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 45.82 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1127 APELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAP-KLEPSTSTDQPVTPEPTSQAT--RGRTNRSSVKTPE 1203
Cdd:pfam04747 189 APAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAAPaSVEQVVEQPKVVTEEPHQQAApqEKKNKKNKRKSES 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1204 TVVPTAPE--LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTsrTTRGRKNRSSV 1281
Cdd:pfam04747 269 ENVPAASEtpVEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLDFV--TAKEEPKDEPA 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1282 KTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKT------PESIVPIAPELQPSTSRNQLVTPEPTSRATR 1355
Cdd:pfam04747 347 ETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDKKKSESekvteqPVESAPAPPQVEQVVETTPPASENKKKNKKD 426
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462611565 1356 CRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLE 1418
Cdd:pfam04747 427 KKKSESEKAVEEPVQAAPSSKKPTADDNMDFLDFVTAKPDKSESVEEHIAAPMIVEPAHADEE 489
|
|
| FHA_AGGF1 |
cd22686 |
forkhead associated (FHA) domain found in angiogenic factor with G patch and FHA domains 1 ... |
46-153 |
2.36e-04 |
|
forkhead associated (FHA) domain found in angiogenic factor with G patch and FHA domains 1 (AGGF1) and similar proteins; AGGF1, also called angiogenic factor VG5Q, or G patch domain-containing protein 7 (GPATC7), or vasculogenesis gene on 5q protein, is an angiogenic factor involved in vascular development, angiogenesis, specification of hemangioblasts, and differentiation of veins. It promotes angiogenesis and the proliferation of endothelial cells. It inhibits inflammatory effect and preserve vascular integrity in non-nervous system diseases. Mutated AGGF1 causes susceptibility to Klippel-Trenaunay syndrome, a vascular disorder. Increased AGGF1 expression is associated with tumor angiogenesis. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438738 [Multi-domain] Cd Length: 123 Bit Score: 42.65 E-value: 2.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 46 RCNVEPVGRLHIFS--GAhgpekdfplhlgknVVGRMPDCSVALPFP--SISKQHAEIEILAWDKAPILRDCGS-----L 116
Cdd:cd22686 11 ESPSLQVGSLFIVTatGA--------------TIGREKDHGHTIRIPelGVSKFHAEIYYDDDEQSYTIVDLGSqngtyL 76
|
90 100 110
....*....|....*....|....*....|....*...
gi 2462611565 117 NGTQILRPPKVLSP-GVSHrlRDQELILFADLLCQYHR 153
Cdd:cd22686 77 NGVRISQPKEKSDPyPLTH--GDELKIGETTLLFHIHP 112
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
869-1060 |
3.88e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 869 SSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRtnrssvktpEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRK 948
Cdd:PRK07764 600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPA---------EASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 949 SRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTD--QPVTSEPTYQAT 1026
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADdpVPLPPEPDDPPD 750
|
170 180 190
....*....|....*....|....*....|....*.
gi 2462611565 1027 RGRKNRSSVKTPEPVVPTAP--ELRPSTSTDRPVTP 1060
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPaaAPPPSPPSEEEEMA 786
|
|
| Yop-YscD_cpl |
pfam16697 |
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain ... |
57-140 |
4.54e-04 |
|
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain of Yop proteins like YscD from Proteobacteria. YscD forms part of the inner membrane component of the bacterial type III secretion injectosome apparatus.
Pssm-ID: 465238 [Multi-domain] Cd Length: 94 Bit Score: 41.09 E-value: 4.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 57 IFSGAH-GpeKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILA--WdkapILRDCGSLNGT-----------QIL 122
Cdd:pfam16697 2 VLSGPHaG--AEFPLEGGRYRIGSDPDCDIVLSDKEVSRVHLKLEVDDegW----RLDDLGSGNGTlvngqrvtelgIAL 75
|
90
....*....|....*....
gi 2462611565 123 RPPKVLSPGVSH-RLRDQE 140
Cdd:pfam16697 76 RPGDRIELGQTEfCLVPAD 94
|
|
| DUF4775 |
pfam16001 |
Domain of unknown function (DUF4775); This family of proteins is functionally uncharacterized. ... |
946-1324 |
4.65e-04 |
|
Domain of unknown function (DUF4775); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 308 and 484 amino acids in length.
Pssm-ID: 406411 [Multi-domain] Cd Length: 456 Bit Score: 44.73 E-value: 4.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 946 GRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRS-SVKTPEPVVPTAPELQPSTSTDQPV-----TS 1019
Cdd:pfam16001 30 GRRTRSSTRGTPTRSAETVTPPPSKKARTSPATATKSSGGKGRGARKlDVGAEEPVEQETKKKKKVQNEPEAKeekekVS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1020 EPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPET-VVPTAPEL-QISTSTDQ 1097
Cdd:pfam16001 110 EPVKGKPAAKKEKKEEKKQKKKEADEKEVVEEKEKEDKEEEKTETKETDAKTAESKDQPDGVgQLPAVAEEkQNHVDEDK 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1098 PVTPKPTSR------TTRSRTNMSSVKNPEST-VPIAPELPPST------STEQPVTPEPTSRATRGRKNRSSGKTPETL 1164
Cdd:pfam16001 190 PETEEPEEKektpeeVAKAEEPPKTSENGAATdTPAAVPESESAmevdeeEKLQENTPQATADAPSDDKAVPDIKVEEKV 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1165 VPTAPKLEPSTSTDQPV---TPEPTSQATrgrTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVK 1241
Cdd:pfam16001 270 AAVSESSEEPKETSEPAkepTPEPMEVDS---SSKGSSDTAQVDTPVKEVVPAAPATESAVAAESTEASNSNNEVVEVAT 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1242 TPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPeLQPSTSTDQPVTPEPTSRATRGRTNRSS 1321
Cdd:pfam16001 347 EVKEDVPEVPPKEAESSEEPAKEAESTTAENSTPVADEVATAPASNDVSKP-VAPVAVIDTTLVETPESPVKEPQVICEV 425
|
...
gi 2462611565 1322 VKT 1324
Cdd:pfam16001 426 NKS 428
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
897-1065 |
4.71e-04 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 44.65 E-value: 4.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 897 KPTSQATRSRTNRSSVKTPEPVVPT--APELQPSTSTDQPVTSEPTSQVT---RGRKSRSSVKTPETVVPTALELQPSTS 971
Cdd:pfam05539 167 EPKTAVTTSKTTSWPTEVSHPTYPSqvTPQSQPATQGHQTATANQRLSSTepvGTQGTTTSSNPEPQTEPPPSQRGPSGS 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 972 TDRPVTSEPTSQATRGRKNRSsvkTPEPVVPTAPElqPSTSTDQPVTSEPTYQATRGRKnrssvKTPEPVVPTAPELRPS 1051
Cdd:pfam05539 247 PQHPPSTTSQDQSTTGDGQEH---TQRRKTPPATS--NRRSPHSTATPPPTTKRQETGR-----PTPRPTATTQSGSSPP 316
|
170
....*....|....
gi 2462611565 1052 TSTDRPVTPKPTSR 1065
Cdd:pfam05539 317 HSSPPGVQANPTTQ 330
|
|
| FHA_EspA-like |
cd22698 |
forkhead associated (FHA) domain found in Myxococcus xanthus EspA and similar proteins; EspA ... |
63-121 |
5.13e-04 |
|
forkhead associated (FHA) domain found in Myxococcus xanthus EspA and similar proteins; EspA is a histidine protein kinase with a fork head-associated (FHA) domain at the N-terminus and a receiver domain at the C-terminus. It functions as an inhibitor of sporulation during early fruiting body development while cells are aggregating into raised mounds. EspA is part of a two-component signal transduction system that regulates the timing of sporulation initiation. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438750 [Multi-domain] Cd Length: 93 Bit Score: 40.86 E-value: 5.13e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462611565 63 GPEKDFPLHL--GKNVVGRMPDCSVALPFPSISKQHAEIEiLAWDKApILRDCGSLNGTQI 121
Cdd:cd22698 9 GSEEGKDYELdqDEFTIGRSSNNDIRLNDHSVSRHHARIV-RQGDKC-NLTDLGSTNGTFL 67
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1090-1229 |
7.51e-04 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 43.94 E-value: 7.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1090 QISTSTDQPVTPKPTSrttrSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAP 1169
Cdd:PRK12799 292 QIDTHGTVPVAAVTPS----SAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALP 367
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1170 KLEPSTSTDQPVTPEPTSQATRGRTNRSSvKTPETVVPTAPelqpststDQPVTPEPTSQ 1229
Cdd:PRK12799 368 AAEPVNMQPQPMSTTETQQSSTGNITSTA-NGPTTSLPAAP--------ASNIPVSPTSR 418
|
|
| FHA_Cep170 |
cd22704 |
forkhead associated (FHA) domain found in the centrosomal protein of 170 kDa protein (Cep170) ... |
77-119 |
1.16e-03 |
|
forkhead associated (FHA) domain found in the centrosomal protein of 170 kDa protein (Cep170) family; The Cep170 family includes Cep170 and Cep170B. Cep170, also called Cep170A, KARP-1-binding protein, or KARP1-binding protein, is a protein that localizes to centrosomes as well as spindle microtubules and plays a role in microtubule organization and microtubule assembly. It is required for centriole subdistal appendage assembly. Cep170 is phosphorylated during M phase and interacts with Polo-like kinase 1 (Plk1). Cep170B, also called centrosomal protein 170B, plays a role in microtubule organization. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438756 [Multi-domain] Cd Length: 102 Bit Score: 40.00 E-value: 1.16e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 2462611565 77 VGRmPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGT 119
Cdd:cd22704 21 VGR-EDCDLILQSRSVDKQHAVITYDQIDNEFKIKDLGSLNGT 62
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1200-1421 |
1.18e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 43.76 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1200 KTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSS---VKTPETVVPTAPELQASASTDQPVTSEPTSRTTrgrk 1276
Cdd:PLN03209 337 DGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPLSPYTAyedLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDV---- 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1277 nrSSVKTPETVVPAAPELQPSTSTDQPVTP--------EPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPE 1348
Cdd:PLN03209 413 --VPSPGSASNVPEVEPAQVEAKKTRPLSPyaryedlkPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPP 490
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462611565 1349 PT-SRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPvepaaSDLEPFT 1421
Cdd:PLN03209 491 PAnMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQPKP-----RPLSPYT 559
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
833-1239 |
1.23e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.82 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 833 PTVRKTRQDGSQEAPEAPlsselEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSV 912
Cdd:PRK07764 418 AAAAAPAPAAAPQPAPAP-----APAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA 492
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 913 KTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVV----PTALELQPSTSTDR-----PVTSEPTSQ 983
Cdd:PRK07764 493 APAAPAAPAAPAGADDAATLRERWPEILAAVPKRSRKTWAILLPEATVlgvrGDTLVLGFSTGGLArrfasPGNAEVLVT 572
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 984 ATRGRKNRssVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRgrknrssvktpepvvPTAPElrpstSTDRPVTPKPT 1063
Cdd:PRK07764 573 ALAEELGG--DWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAAR---------------PAAPA-----APAAPAAPAPA 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1064 SRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSrtnmssvknPESTVPIAPELPPSTSTEQPVTPE 1143
Cdd:PRK07764 631 GAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAA---------PAAPPPAPAPAAPAAPAGAAPAQP 701
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1144 PTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTD--QPVTPEPTSQATRGRTNRSSVKTPETVVPTAP--ELQPSTSTD 1219
Cdd:PRK07764 702 APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADdpVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPaaAPPPSPPSE 781
|
410 420
....*....|....*....|
gi 2462611565 1220 QPVTPEPTSQATRGRTDRSS 1239
Cdd:PRK07764 782 EEEMAEDDAPSMDDEDRRDA 801
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
793-1304 |
1.30e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.92 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 793 ACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELE-PFHPKPKIRTRKSSR 871
Cdd:PRK10263 335 APVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQqPVQPQQPYYAPAAEQ 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 872 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTP-----------EPVVPTAPELQPStSTDQPVTSEPT 940
Cdd:PRK10263 415 PAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPqstyqteqtyqQPAAQEPLYQQPQ-PVEQQPVVEPE 493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 941 SQVTRGRKSRSSVKTPETVVPT-ALELQPSTSTDRPVtSEPtsqatrgrknrssVKTPEPVVPTAPelQPSTSTDQPVTS 1019
Cdd:PRK10263 494 PVVEETKPARPPLYYFEEVEEKrAREREQLAAWYQPI-PEP-------------VKEPEPIKSSLK--APSVAAVPPVEA 557
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1020 EPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTS-TDRPVT--------PKPTSRTTRSRTNMSS--VKTPETVV----- 1083
Cdd:PRK10263 558 AAAVSPLASGVKKATLATGAAATVAAPVFSLANSgGPRPQVkegigpqlPRPKRIRVPTRRELASygIKLPSQRAaeeka 637
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1084 ------PTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSS 1157
Cdd:PRK10263 638 reaqrnQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPA 717
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1158 GKTPETL--------------VPTAPKLEPS-----TSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQpstST 1218
Cdd:PRK10263 718 GANPFSLddfefspmkallddGPHEPLFTPIvepvqQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQ---QP 794
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1219 DQPVTPEPTSQATRGRT-DRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSS-VKTPETVVPAAPELQP 1296
Cdd:PRK10263 795 QQPVAPQPQYQQPQQPVaPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRpLHKPTTPLPSLDLLTP 874
|
....*...
gi 2462611565 1297 STSTDQPV 1304
Cdd:PRK10263 875 PPSEVEPV 882
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1170-1311 |
1.45e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 43.17 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1170 KLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPT 1249
Cdd:PRK12799 286 KATGLKQIDTHGTVPVAAVTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVA 365
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462611565 1250 APELQASASTDQPVTSEPTSRTTRGRKNRSSvKTPETVVPAAPelqpststDQPVTPEPTSR 1311
Cdd:PRK12799 366 LPAAEPVNMQPQPMSTTETQQSSTGNITSTA-NGPTTSLPAAP--------ASNIPVSPTSR 418
|
|
| COG3456 |
COG3456 |
Predicted component of the type VI protein secretion system, contains a FHA domain [Signal ... |
76-147 |
1.52e-03 |
|
Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442679 [Multi-domain] Cd Length: 402 Bit Score: 43.21 E-value: 1.52e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462611565 76 VVGRMPDCSVALPFPS--ISKQHAEIEILawDKAPILRDCgSLNGTQILRPPKVLSPGVSHRLRDQELILFADL 147
Cdd:COG3456 29 TIGRSADCDWVLPDPDrsVSRRHAEIRFR--DGAFCLTDL-STNGTFLNGSDHPLGPGRPVRLRDGDRLRIGDY 99
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
1009-1209 |
1.76e-03 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 42.87 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1009 PSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPelRPSTSTDRPVTPK-PTSRTTRSR----------------- 1070
Cdd:PRK13914 147 PVAPTQEVKKETTTQQAAPAAETKTEVKQTTQATTPAP--KVAETKETPVVDQnATTHAVKSGdtiwalsvkygvsvqdi 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1071 ---TNMSS--------VKTPETVVPTAPELQisTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE-- 1137
Cdd:PRK13914 225 mswNNLSSssiyvgqkLAIKQTANTATPKAE--VKTEAPAAEKQAAPVVKENTNTNTATTEKKETTTQQQTAPKAPTEaa 302
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462611565 1138 QPvTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTA 1209
Cdd:PRK13914 303 KP-APAPSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGSSNNNSNSSASAIIAEA 373
|
|
| PHA03255 |
PHA03255 |
BDLF3; Provisional |
1227-1388 |
1.77e-03 |
|
BDLF3; Provisional
Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 42.20 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1227 TSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPelqpstSTDQPVTP 1306
Cdd:PHA03255 27 SGSSTASAGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPVP------TTSNASTI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1307 EPTSRATRGRTNRSSVKTpesivpiapELQPSTSRNQLVTPEPTSRATRCRTNrSSVKTPEPVVPTAPEPHPTTStDQPV 1386
Cdd:PHA03255 101 NVTTKVTAQNITATEAGT---------GTSTGVTSNVTTRSSSTTSATTRITN-ATTLAPTLSSKGTSNATKTTA-ELPT 169
|
..
gi 2462611565 1387 TP 1388
Cdd:PHA03255 170 VP 171
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
860-974 |
1.82e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.78 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 860 PKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEP 939
Cdd:PRK12799 304 VTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQPQPMSTTE 383
|
90 100 110
....*....|....*....|....*....|....*.
gi 2462611565 940 TSQVTRGrKSRSSVKTPETVVPTALELQ-PSTSTDR 974
Cdd:PRK12799 384 TQQSSTG-NITSTANGPTTSLPAAPASNiPVSPTSR 418
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
858-1047 |
2.00e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.93 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 858 FHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQatrsrtnrssvktPEPVVPTAPELQPSTSTDQPvtS 937
Cdd:PRK07994 359 FHPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPP-------------PASAPQQAPAVPLPETTSQL--L 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 938 EPTSQVTRgRKSRSSVKTPETVVPTALELQPStSTDRPVTSEPTSQATrgrknrssvkTPEPVVPTAPELQPSTSTDQPV 1017
Cdd:PRK07994 424 AARQQLQR-AQGATKAKKSEPAAASRARPVNS-ALERLASVRPAPSAL----------EKAPAKKEAYRWKATNPVEVKK 491
|
170 180 190
....*....|....*....|....*....|
gi 2462611565 1018 TSEPTYQATrgRKNRSSVKTPEPVVPTAPE 1047
Cdd:PRK07994 492 EPVATPKAL--KKALEHEKTPELAAKLAAE 519
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1139-1270 |
2.02e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.78 E-value: 2.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1139 PVTPEPTSRATrgrkNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTST 1218
Cdd:PRK12799 300 PVAAVTPSSAV----TQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQ 375
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2462611565 1219 DQPVTPEPTSQATRGRTDRSSvKTPETVVPTAPELQASAStdqpvtsePTSR 1270
Cdd:PRK12799 376 PQPMSTTETQQSSTGNITSTA-NGPTTSLPAAPASNIPVS--------PTSR 418
|
|
| FHA_SNIP1_DDL-like |
cd22676 |
forkhead associated (FHA) domain found in Smad nuclear-interacting protein 1 (SNIP1), FHA ... |
54-145 |
2.03e-03 |
|
forkhead associated (FHA) domain found in Smad nuclear-interacting protein 1 (SNIP1), FHA domain-containing protein DDL, and similar proteins; SNIP1 is an FHA domain-containing protein required for pre-mRNA splicing as a component of the spliceosome. It inhibits NF-kappaB signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. It is involved in microRNA (miRNA) biogenesis. SNIP1 is a regulator of the cell cycle and cyclin D1 expression and may be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. This family also includes Arabidopsis thaliana FHA domain-containing protein DDL and similar proteins. DDL, also called protein DAWDLE, is involved in the microRNA (miRNA) and short interfering RNA (siRNA) biogenesis. It may facilitate DCL1 to access or recognize primary miRNAs. DDL binds RNA non-specifically. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438728 [Multi-domain] Cd Length: 111 Bit Score: 39.59 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 54 RLHIFSGAHGPEkdfPLHLGKN---VVGRMPD-CSVALPFPSISKQHAEIEILAWDK----------APILRDCGSLNGT 119
Cdd:cd22676 2 RLYVFKGGEQLE---TIDIHRQsayLIGRDRRvADIPLDHPSCSKQHAVIQFREVEKrnegdvieniRPYIIDLGSTNGT 78
|
90 100
....*....|....*....|....*.
gi 2462611565 120 QILRPPkvLSPGVSHRLRDQELILFA 145
Cdd:cd22676 79 FLNGEK--IEPRRYYELREKDVLKFG 102
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
1209-1340 |
2.22e-03 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 43.16 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1209 APEL--QPSTSTDQPVTPEPTSQATrgrtdrssvkTPETVVPTAPELQASaSTDQPVTSEPTSRTTRGRKNRSSVKTPET 1286
Cdd:NF033875 43 AAELdtQPGTTTVQPDNPDPQSGSE----------TPKTAVSEEATVQKD-TTSQPTKVEEVASEKNGAEQSSATPNDTT 111
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2462611565 1287 VVPAAPELQPSTSTDQPVTPEPTSRATRGRtnrssvktPESIVPIAPELQPSTS 1340
Cdd:NF033875 112 NAQQPTVGAEKSAQEQPVVSPETTNEPLGQ--------PTEVAPAENEANKSTS 157
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
898-1471 |
2.47e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.83 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 898 PTSQATRS--RTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRP 975
Cdd:pfam03154 34 PTNEDLRSsgRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSAKRQREKGASDTEEPERATAKKSKTQEISRPNSP 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 976 VTSEPTSQATRGRKNRSSvKTPEPVVPTAPELQPSTST--DQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTS 1053
Cdd:pfam03154 114 SEGEGESSDGRSVNDEGS-SDPKDIDQDNRSTSPSIPSpqDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTT 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1054 TDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSrttrsrtnmssvknPESTVPIAPELPPS 1133
Cdd:pfam03154 193 QAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPS--------------PHPPLQPMTQPPPP 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1134 TSTEQPVTPEPTSRATRGRKNRSSGKTPETL---VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPEtvvPTAP 1210
Cdd:pfam03154 259 SQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMqhpVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQ---SQLQ 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1211 ELQPstSTDQPVTPEPTSQatrgrtdrssvktpetvvptaPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPA 1290
Cdd:pfam03154 336 SQQP--PREQPLPPAPLSM---------------------PHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPP 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1291 APELQP--STSTDQPVTPEPtsratrgrtnrssvkTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEP 1368
Cdd:pfam03154 393 PPALKPlsSLSTHHPPSAHP---------------PPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVP 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1369 VVPTAPEPHPTTSTDQPVTPKLTsratrrktnrssvkTPKPVEPAASDLEPftPTDQSVTPEAIAQGGQSKTLRSSTVRA 1448
Cdd:pfam03154 458 SQSPFPQHPFVPGGPPPITPPSG--------------PPTSTSSAMPGIQP--PSSASVSSSGPVPAAVSCPLPPVQIKE 521
|
570 580
....*....|....*....|...
gi 2462611565 1449 MPVPTTPEFQSPVTTDQPISPEP 1471
Cdd:pfam03154 522 EALDEAEEPESPPPPPRSPSPEP 544
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1050-1299 |
2.69e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 42.61 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1050 PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTS-RTTRSRTNMSSVKNPESTVPIap 1128
Cdd:PLN03209 312 PLTPMEELLAKIPSQRVPPKESDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVpRPLSPYTAYEDLKPPTSPIPT-- 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1129 elPPSTSTEQPVTPEPTSRATRGRKNRSSGKT---PETLVPTAPK-----LEPSTSTDQ---PVTPEPTSQATRGRTNRS 1197
Cdd:PLN03209 390 --PPSSSPASSKSVDAVAKPAEPDVVPSPGSAsnvPEVEPAQVEAkktrpLSPYARYEDlkpPTSPSPTAPTGVSPSVSS 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1198 S---VKTPETVVPTA--PELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTT 1272
Cdd:PLN03209 468 TssvPAVPDTAPATAatDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHH 547
|
250 260
....*....|....*....|....*..
gi 2462611565 1273 RGRKNRssvktPETVVPAAPELQPSTS 1299
Cdd:PLN03209 548 AQPKPR-----PLSPYTMYEDLKPPTS 569
|
|
| FHA_ZEP-like |
cd22702 |
forkhead associated (FHA) domain found in chloroplastic zeaxanthin epoxidase (ZEP) and similar ... |
69-144 |
3.02e-03 |
|
forkhead associated (FHA) domain found in chloroplastic zeaxanthin epoxidase (ZEP) and similar proteins; ZEP, also called protein ABA DEFICIENT 1, ABA1, protein IMPAIRED IN BABA-INDUCED STERILITY 3, protein LOW EXPRESSION OF OSMOTIC STRESS-RESPONSIVE GENES 6, or protein NON-PHOTOCHEMICAL QUENCHING 2, plays an important role in the xanthophyll cycle and abscisic acid (ABA) biosynthesis. It converts zeaxanthin into antheraxanthin and subsequently violaxanthin. ZEP is required for resistance to osmotic and drought stresses, ABA-dependent stomatal closure, seed development and dormancy, modulation of defense gene expression, and disease resistance and non-photochemical quencing (NPQ). The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438754 [Multi-domain] Cd Length: 123 Bit Score: 39.33 E-value: 3.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 69 PLHLGKN-----VVGRMPDC-----SVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQILRPP---KVLSPGVSHR 135
Cdd:cd22702 23 PIRLTRDekqpcIIGSDPHQaisgiSVVIPSPQVSELHARITCK--NGAFFLTDLGSEHGTWINDNEgrrYRAPPNFPVR 100
|
....*....
gi 2462611565 136 LRDQELILF 144
Cdd:cd22702 101 LHPSDVIEF 109
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1073-1340 |
4.15e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 41.84 E-value: 4.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1073 MSSVKTPETVVPTAPELqisTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPvtpePTSRATRGR 1152
Cdd:PLN03209 297 LSYCKVVEVIAETTAPL---TPMEELLAKIPSQRVPPKESDAADGPKPVPTKPVTPEAPSPPIEEEP----PQPKAVVPR 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1153 KNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPeLQPSTSTDQPVTP-------- 1224
Cdd:PLN03209 370 PLSPYTAYEDLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEP-AQVEAKKTRPLSPyaryedlk 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1225 EPTSQATRGRTDRSSVKTPETVVPTAPELQ-ASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQP 1303
Cdd:PLN03209 449 PPTSPSPTAPTGVSPSVSSTSSVPAVPDTApATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNE 528
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2462611565 1304 VTP----EPTSRATRGRTNRSSVKTPESIVPIAPELQPSTS 1340
Cdd:PLN03209 529 VVKvgnsAPPTALADEQHHAQPKPRPLSPYTMYEDLKPPTS 569
|
|
| Chi1 |
COG3469 |
Chitinase [Carbohydrate transport and metabolism]; |
877-1106 |
4.58e-03 |
|
Chitinase [Carbohydrate transport and metabolism];
Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 41.66 E-value: 4.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 877 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTP 956
Cdd:COG3469 1 SSSVSTAASPTAGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 957 ETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNrSSVK 1036
Cdd:COG3469 81 TATAAAAAATSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSG-TETA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1037 TPEPVVPTAPELRPSTSTDRPVTPKPTsrttrsrtnmssvkTPETVVPTAPELQISTSTDQPVTPKPTSR 1106
Cdd:COG3469 160 TGGTTTTSTTTTTTSASTTPSATTTAT--------------ATTASGATTPSATTTATTTGPPTPGLPKH 215
|
|
| FHA_RAD53-like_rpt2 |
cd22690 |
second forkhead associated (FHA) domain found in Saccharomyces cerevisiae Serine ... |
53-148 |
5.26e-03 |
|
second forkhead associated (FHA) domain found in Saccharomyces cerevisiae Serine/threonine-protein kinase RAD53 and similar proteins; RAD53, also called CHEK2 homolog, or serine-protein kinase 1 (Spk1), is a nuclear protein kinase that phosphorylates proteins on serine, threonine, and tyrosine. It controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints and prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. It may be involved in the phosphorylation of RPH1. RAD53 contains two FHA domains. This model corresponds to the second one. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438742 [Multi-domain] Cd Length: 105 Bit Score: 38.43 E-value: 5.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 53 GRLHIFSGAHgpeKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPI---LRDCgSLNGTQILRppKVLS 129
Cdd:cd22690 2 GRLKSLNPSY---PDIELTQNTTFIGRSKDCDEEITDPRISKHHCIITRKRSGKGLDdvyVTDT-STNGTFINN--NRLG 75
|
90 100
....*....|....*....|
gi 2462611565 130 PGVSHRLRD-QELILFADLL 148
Cdd:cd22690 76 KGSQSLLQDgDEIVLIWDKN 95
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
879-1147 |
5.31e-03 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 41.59 E-value: 5.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 879 SAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAP-ELQPSTSTDQPVTSEPTSQVTRGRK--SRSSVKT 955
Cdd:pfam04747 187 SAAPAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAAPaSVEQVVEQPKVVTEEPHQQAAPQEKknKKNKRKS 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 956 PETVVPTALE--LQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQpvTSEPTYQATRGRKNRS 1033
Cdd:pfam04747 267 ESENVPAASEtpVEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDN--MDFLDFVTAKEEPKDE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1034 SVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETvvptapelqistsTDQPV--TPKPTSRTTRSR 1111
Cdd:pfam04747 345 PAETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDKKKSESEKV-------------TEQPVesAPAPPQVEQVVE 411
|
250 260 270
....*....|....*....|....*....|....*.
gi 2462611565 1112 TNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSR 1147
Cdd:pfam04747 412 TTPPASENKKKNKKDKKKSESEKAVEEPVQAAPSSK 447
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
1191-1475 |
5.91e-03 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 41.52 E-value: 5.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1191 RGRTNRSSVKTPETVVPTAPeLQPSTSTDQPVTPEPTSQAT---RGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1267
Cdd:PHA03369 340 GLKAHNEILKTASLTAPSRV-LAAAAKVAVIAAPQTHTGPAdrqRPQRPDGIPYSVPARSPMTAYPPVPQFCGDPGLVSP 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1268 TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRAT-RGRTNRSSVKtpESIVPIAPELQPSTSRNQLVT 1346
Cdd:PHA03369 419 YNPQSPGTSYGPEPVGPVPPQPTNPYVMPISMANMVYPGHPQEHGHeRKRKRGGELK--EELIETLKLVKKLKEEQESLA 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1347 PEPTSRATRCRTNRSS--------VKTPEPVV---PTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAAS 1415
Cdd:PHA03369 497 KELEATAHKSEIKKIAesefknagAKTAAANIepnCSADAAAPATKRARPETKTELEAVVRFPYQIRNMESPAFVHSFTS 576
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462611565 1416 DLEPFTPTDQSVTPEAIAqgGQSKTLrSSTVRAMPVPTTPEFQ-------SPVTTDQPISPEPITQP 1475
Cdd:PHA03369 577 TTLAAAAGQGSDTAEALA--GAIETL-LTQASAQPAGLSLPAPavpvnasTPASTPPPLAPQEPPQP 640
|
|
| FHA_Rv1747-like_rpt2 |
cd22737 |
second forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ... |
77-119 |
7.04e-03 |
|
second forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ATP-binding/permease protein Rv1747 and similar proteins; Rv1747 is a putative ATP-binding cassette (ABC) transporter involved in the translocation of an unknown substrate across the membrane. It is required for normal virulent infection by M. tuberculosis. Rv1747 has a cytoplasmic regulatory module consisting of two pThr-interacting forkhead-associated (FHA) domains connected by a conformationally disordered linker with two phospho-acceptor threonines (pThr). Recruitment and phosphorylation of Rv1747 depend on the interaction between its two non-redundant FHA domains and the autophosphorylated form of serine/threonine protein kinase PknF. This model corresponds to the second FHA domain, which has a circularly permuted FHA domain fold with a conserved pThr-binding interface.
Pssm-ID: 439356 [Multi-domain] Cd Length: 93 Bit Score: 37.47 E-value: 7.04e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 2462611565 77 VGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGT 119
Cdd:cd22737 25 IGRASDNDIVIPEGSVSRHHATLVPT--PGGTQIRDLRSTNGT 65
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1295-1637 |
7.35e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.31 E-value: 7.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1295 QPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPvvptAP 1374
Cdd:PHA03307 40 QGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSS----PD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1375 EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAiaqggqsktlrsSTVRAMPVPTT 1454
Cdd:PHA03307 116 PPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQA------------ALPLSSPEETA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1455 PEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPK-SQASRNQRWGAVRAAESLTAIPEPaSP 1533
Cdd:PHA03307 184 RAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASsSDSSSSESSGCGWGPENECPLPRP-AP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1534 QLLETPIHASQIQKVE-----PAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQ--PQRGEVSQKTVIIKEEEEDTAEK 1606
Cdd:PHA03307 263 ITLPTRIWEASGWNGPssrpgPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSssSSRESSSSSTSSSSESSRGAAVS 342
|
330 340 350
....*....|....*....|....*....|.
gi 2462611565 1607 PGKEEDvvtpKPGKRKRDQAEEEPNRIPSRS 1637
Cdd:PHA03307 343 PGPSPS----RSPSPSRPPPPADPSSPRKRP 369
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1185-1424 |
7.77e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 41.37 E-value: 7.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1185 PTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1264
Cdd:PRK07003 381 PAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASAD 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1265 SEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPvtPEPTSRATRGRTNRSSVKTPESIVPIAPElQPSTSRNQL 1344
Cdd:PRK07003 461 SRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAP--SAATPAAVPDARAPAAASREDAPAAAAPP-APEARPPTP 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1345 VTPEPTSRAT--------------RCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTpKPV 1410
Cdd:PRK07003 538 AAAAPAARAGgaaaaldvlrnagmRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGA-ARA 616
|
250
....*....|....
gi 2462611565 1411 EPAASDLEPFTPTD 1424
Cdd:PRK07003 617 EQAAESRGAPPPWE 630
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
1129-1419 |
8.00e-03 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 40.82 E-value: 8.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1129 ELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLV--------PTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVK 1200
Cdd:pfam04747 142 KLQAEKKKEKAVKAEKAEKAEKTKKASTPAPVEEEIVvkkvandrSAAPAPEPKTPTNTPAEPAEQVQEITGKKNKKNKK 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1201 TPETVVPTAP-ELQPSTSTDQPVTPEPTSQAT--RGRTDRSSVKTPETVVPTAPELQASASTD-QPVTSEPTSRTTRGRK 1276
Cdd:pfam04747 222 KSESEATAAPaSVEQVVEQPKVVTEEPHQQAApqEKKNKKNKRKSESENVPAASETPVEPVVEtTPPASENQKKNKKDKK 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1277 NRSSVKTPETVVPA-APELQPSTSTDQPVTPEPTSraTRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATR 1355
Cdd:pfam04747 302 KSESEKVVEEPVQAeAPKSKKPTADDNMDFLDFVT--AKEEPKDEPAETPAAPVEEVVENVVENVVEKSTTPPATENKKK 379
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1356 CRTNR----SSVKTPEPV--VPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEP 1419
Cdd:pfam04747 380 NKKDKkkseSEKVTEQPVesAPAPPQVEQVVETTPPASENKKKNKKDKKKSESEKAVEEPVQAAPSSKKP 449
|
|
| FHA_Rv1747-like_rpt1 |
cd22694 |
first forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ... |
76-119 |
9.42e-03 |
|
first forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ATP-binding/permease protein Rv1747 and similar proteins; Rv1747 is a putative ATP-binding cassette (ABC) transporter involved in the translocation of an unknown substrate across the membrane. It is required for normal virulent infection by M. tuberculosis. Rv1747 has a cytoplasmic regulatory module consisting of two pThr-interacting forkhead-associated (FHA) domains connected by a conformationally disordered linker with two phospho-acceptor threonines (pThr). Recruitment and phosphorylation of Rv1747 depend on the interaction between its two non-redundant FHA domains and the autophosphorylated form of serine/threonine protein kinase PknF. This model corresponds to the first FHA domain. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438746 [Multi-domain] Cd Length: 93 Bit Score: 37.31 E-value: 9.42e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 2462611565 76 VVGRMPDCSVALPFPSISKQHAEIEIL--AWdkapILRDCGSLNGT 119
Cdd:cd22694 19 RIGRDPDADVRLDDPRVSRRHALLEFDgdGW----VYTDLGSRNGT 60
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
796-996 |
9.59e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.01 E-value: 9.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 796 PPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPkiRTRKSSRMTPF 875
Cdd:PRK12323 374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQAS--ARGPGGAPAPA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 876 PATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEP-VVPTAPELQPSTSTDQPVTSEPT-SQVTRGRKSRSSV 953
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADdDPPPWEELPPEFASPAPAQPDAApAGWVAESIPDPAT 531
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2462611565 954 KTPETVVPTALELQPSTSTDRP-VTSEPTSQATRGRKNRSSVKT 996
Cdd:PRK12323 532 ADPDDAFETLAPAPAAAPAPRAaAATEPVVAPRPPRASASGLPD 575
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1126-1368 |
9.97e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 40.68 E-value: 9.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1126 IAPELPPSTSTEQPVTPEPTSRATRgrKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRG---RTNRSSVKTP 1202
Cdd:PLN03209 306 IAETTAPLTPMEELLAKIPSQRVPP--KESDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPlspYTAYEDLKPP 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1203 ETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSvKTPETVVPTAPELQA---SASTDQPVTSEPTSRTTRGRKNRS 1279
Cdd:PLN03209 384 TSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSPGSAS-NVPEVEPAQVEAKKTrplSPYARYEDLKPPTSPSPTAPTGVS 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462611565 1280 SVKTPETVVPAAPELQPSTS-TDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRT 1358
Cdd:PLN03209 463 PSVSSTSSVPAVPDTAPATAaTDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALA 542
|
250
....*....|
gi 2462611565 1359 NRSSVKTPEP 1368
Cdd:PLN03209 543 DEQHHAQPKP 552
|
|
| |
