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Conserved domains on  [gi|2462622953|ref|XP_054218105|]
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FRAS1-related extracellular matrix protein 1 isoform X13 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Cadherin_3 pfam16184
Cadherin-like;
405-511 1.23e-34

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 128.49  E-value: 1.23e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  405 RSAPMTVHISIRTADTNAPRVSWNTGLSLLEGQSRAITWEQFQLVDNDDI-GAVRLVTVGGLQHGWLTLRGGKGFL---F 480
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPGLPvtnF 80
                           90       100       110
                   ....*....|....*....|....*....|.
gi 2462622953  481 TVADLQAGVVRYHHDDSDSTKDFVVFRIFDG 511
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1267-1383 4.52e-29

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 112.70  E-value: 4.52e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953 1267 HKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKiGRDWVPLSp 1346
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALK-GAPGLPVT- 78
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2462622953 1347 gmKCTQEEVDLNLLRYTHTGamDSQNQDSFTFYLWDG 1383
Cdd:pfam16184   79 --NFTQADIDSGLVVYVHDG--SESTSDGFTFQVTDG 111
Frem_N super family cl44740
Frem protein N-terminal domain; This entry represents a presumed domain found at the ...
29-269 3.57e-28

Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.


The actual alignment was detected with superfamily member pfam19309:

Pssm-ID: 466034  Cd Length: 202  Bit Score: 113.19  E-value: 3.57e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953   29 NRGVRVMKGHSAFLSG-DDLKFAIPKeKDACKVEVVMNEPITQRVGKLTPQVFDCHFLPNEVKYVHNGCPILDEDTVKLR 107
Cdd:pfam19309    5 NRGLRVPFGRSVWLDPlRDLVIQVQP-GDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRVRLQ 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  108 LYRFTERDTFIETFILWVYLLEPDCNIIhMSNNVLEVPEFNGLSQAIDKNLLRFDYDRmASLECTVSLDTARTRLPAHGQ 187
Cdd:pfam19309   84 LRYDAPTDTLVLPFTLEVEVVFSQLEIV-TRNLPLTVEKLLGTSNPIDRRVLEFAYDP-GTERCKVTVLPGAGGLPRYGR 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  188 MVlgeprpeeprgdqphsffpesrmmsfNAflelraklkcpggsctPGLkkigSLKVSCEEFLLMGLRYQHL-DPPSPNI 266
Cdd:pfam19309  162 LV--------------------------NA----------------TGA----PLMVDCEAFLRAGVRYQHTaTTSSPNR 195

                   ...
gi 2462622953  267 DYI 269
Cdd:pfam19309  196 DYV 198
Cadherin_3 pfam16184
Cadherin-like;
513-625 2.77e-27

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 107.30  E-value: 2.77e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  513 HSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITKPPQAGEIMKKPGPGLigyPV 592
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL---PV 77
                           90       100       110
                   ....*....|....*....|....*....|...
gi 2462622953  593 HGFLQRDLFNGIIYYRHFGGEIFEDSFQFVLWD 625
Cdd:pfam16184   78 TNFTQADIDSGLVVYVHDGSESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
775-878 1.72e-23

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 96.52  E-value: 1.72e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  775 FNITILPVDNQVPEAFTN-PLKVTEGGQSIISTEHILIYDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLH 853
Cdd:pfam16184    7 FNITIIPVNDEAPVLTTNtGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQADID 86
                           90       100
                   ....*....|....*....|....*
gi 2462622953  854 TLKVRYQHDGTEVLQDDLLLEVTDG 878
Cdd:pfam16184   87 SGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1140-1265 5.50e-23

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 94.98  E-value: 5.50e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953 1140 HSLEIPFSIIINPTNDEAPDfVVQN--ITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLidrgfskdfsen 1217
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPV-LTTNtgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHL------------ 67
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2462622953 1218 kqpANPHQKHAPVHSFSMELLKTGmRLTYMHDDSESLADDFTIQLSDG 1265
Cdd:pfam16184   68 ---ALKGAPGLPVTNFTQADIDSG-LVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1016-1137 6.30e-23

Cadherin-like;


:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 94.98  E-value: 6.30e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953 1016 SFPVYdLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENilpsvgfeKSN 1095
Cdd:pfam16184    2 SVPFT-FNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGA 72
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 2462622953 1096 IGISIDSFQWKDMNAFHINYVqsrHLRIEPTADQFTVYVTDG 1137
Cdd:pfam16184   73 PGLPVTNFTQADIDSGLVVYV---HDGSESTSDGFTFQVTDG 111
Cadherin_3 super family cl28802
Cadherin-like;
880-993 2.45e-18

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 81.88  E-value: 2.45e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  880 NSAEFVLHVEVFPVNDEPPVLKADlmPVMNCSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHG---VVRRAGVTVD 956
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTN--TGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGhlaLKGAPGLPVT 78
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2462622953  957 QFSQRDVISEAVTYKHTGGEiglmPCFDTITLVVSDG 993
Cdd:pfam16184   79 NFTQADIDSGLVVYVHDGSE----STSDGFTFQVTDG 111
Cadherin_3 super family cl28802
Cadherin-like;
633-764 3.53e-10

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 58.77  E-value: 3.53e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  633 SVPQVATIHITPVDDqlpkEAPGVSRH--LVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPffsfSHRHLdagklf 710
Cdd:pfam16184    2 SVPFTFNITIIPVND----EAPVLTTNtgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP----SHGHL------ 67
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622953  711 mvdsipkVVKNPTALELRSFTQHAVNYMKVAYM----PPMQDigphcrdvQFTFSVSN 764
Cdd:pfam16184   68 -------ALKGAPGLPVTNFTQADIDSGLVVYVhdgsESTSD--------GFTFQVTD 110
Cadherin_3 super family cl28802
Cadherin-like;
324-400 8.47e-07

Cadherin-like;


The actual alignment was detected with superfamily member pfam16184:

Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 49.14  E-value: 8.47e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462622953  324 LTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTWKDLSDMQIAYQppnSSHSERRHDEVELEVYD 400
Cdd:pfam16184   37 ITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV---HDGSESTSDGFTFQVTD 110
 
Name Accession Description Interval E-value
Cadherin_3 pfam16184
Cadherin-like;
405-511 1.23e-34

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 128.49  E-value: 1.23e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  405 RSAPMTVHISIRTADTNAPRVSWNTGLSLLEGQSRAITWEQFQLVDNDDI-GAVRLVTVGGLQHGWLTLRGGKGFL---F 480
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPGLPvtnF 80
                           90       100       110
                   ....*....|....*....|....*....|.
gi 2462622953  481 TVADLQAGVVRYHHDDSDSTKDFVVFRIFDG 511
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1267-1383 4.52e-29

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 112.70  E-value: 4.52e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953 1267 HKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKiGRDWVPLSp 1346
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALK-GAPGLPVT- 78
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2462622953 1347 gmKCTQEEVDLNLLRYTHTGamDSQNQDSFTFYLWDG 1383
Cdd:pfam16184   79 --NFTQADIDSGLVVYVHDG--SESTSDGFTFQVTDG 111
Frem_N pfam19309
Frem protein N-terminal domain; This entry represents a presumed domain found at the ...
29-269 3.57e-28

Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.


Pssm-ID: 466034  Cd Length: 202  Bit Score: 113.19  E-value: 3.57e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953   29 NRGVRVMKGHSAFLSG-DDLKFAIPKeKDACKVEVVMNEPITQRVGKLTPQVFDCHFLPNEVKYVHNGCPILDEDTVKLR 107
Cdd:pfam19309    5 NRGLRVPFGRSVWLDPlRDLVIQVQP-GDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRVRLQ 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  108 LYRFTERDTFIETFILWVYLLEPDCNIIhMSNNVLEVPEFNGLSQAIDKNLLRFDYDRmASLECTVSLDTARTRLPAHGQ 187
Cdd:pfam19309   84 LRYDAPTDTLVLPFTLEVEVVFSQLEIV-TRNLPLTVEKLLGTSNPIDRRVLEFAYDP-GTERCKVTVLPGAGGLPRYGR 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  188 MVlgeprpeeprgdqphsffpesrmmsfNAflelraklkcpggsctPGLkkigSLKVSCEEFLLMGLRYQHL-DPPSPNI 266
Cdd:pfam19309  162 LV--------------------------NA----------------TGA----PLMVDCEAFLRAGVRYQHTaTTSSPNR 195

                   ...
gi 2462622953  267 DYI 269
Cdd:pfam19309  196 DYV 198
Cadherin_3 pfam16184
Cadherin-like;
513-625 2.77e-27

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 107.30  E-value: 2.77e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  513 HSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITKPPQAGEIMKKPGPGLigyPV 592
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL---PV 77
                           90       100       110
                   ....*....|....*....|....*....|...
gi 2462622953  593 HGFLQRDLFNGIIYYRHFGGEIFEDSFQFVLWD 625
Cdd:pfam16184   78 TNFTQADIDSGLVVYVHDGSESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
775-878 1.72e-23

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 96.52  E-value: 1.72e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  775 FNITILPVDNQVPEAFTN-PLKVTEGGQSIISTEHILIYDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLH 853
Cdd:pfam16184    7 FNITIIPVNDEAPVLTTNtGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQADID 86
                           90       100
                   ....*....|....*....|....*
gi 2462622953  854 TLKVRYQHDGTEVLQDDLLLEVTDG 878
Cdd:pfam16184   87 SGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1140-1265 5.50e-23

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 94.98  E-value: 5.50e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953 1140 HSLEIPFSIIINPTNDEAPDfVVQN--ITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLidrgfskdfsen 1217
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPV-LTTNtgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHL------------ 67
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2462622953 1218 kqpANPHQKHAPVHSFSMELLKTGmRLTYMHDDSESLADDFTIQLSDG 1265
Cdd:pfam16184   68 ---ALKGAPGLPVTNFTQADIDSG-LVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1016-1137 6.30e-23

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 94.98  E-value: 6.30e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953 1016 SFPVYdLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENilpsvgfeKSN 1095
Cdd:pfam16184    2 SVPFT-FNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGA 72
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 2462622953 1096 IGISIDSFQWKDMNAFHINYVqsrHLRIEPTADQFTVYVTDG 1137
Cdd:pfam16184   73 PGLPVTNFTQADIDSGLVVYV---HDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
880-993 2.45e-18

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 81.88  E-value: 2.45e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  880 NSAEFVLHVEVFPVNDEPPVLKADlmPVMNCSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHG---VVRRAGVTVD 956
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTN--TGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGhlaLKGAPGLPVT 78
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2462622953  957 QFSQRDVISEAVTYKHTGGEiglmPCFDTITLVVSDG 993
Cdd:pfam16184   79 NFTQADIDSGLVVYVHDGSE----STSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
633-764 3.53e-10

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 58.77  E-value: 3.53e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  633 SVPQVATIHITPVDDqlpkEAPGVSRH--LVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPffsfSHRHLdagklf 710
Cdd:pfam16184    2 SVPFTFNITIIPVND----EAPVLTTNtgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP----SHGHL------ 67
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622953  711 mvdsipkVVKNPTALELRSFTQHAVNYMKVAYM----PPMQDigphcrdvQFTFSVSN 764
Cdd:pfam16184   68 -------ALKGAPGLPVTNFTQADIDSGLVVYVhdgsESTSD--------GFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
324-400 8.47e-07

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 49.14  E-value: 8.47e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462622953  324 LTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTWKDLSDMQIAYQppnSSHSERRHDEVELEVYD 400
Cdd:pfam16184   37 ITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV---HDGSESTSDGFTFQVTD 110
 
Name Accession Description Interval E-value
Cadherin_3 pfam16184
Cadherin-like;
405-511 1.23e-34

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 128.49  E-value: 1.23e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  405 RSAPMTVHISIRTADTNAPRVSWNTGLSLLEGQSRAITWEQFQLVDNDDI-GAVRLVTVGGLQHGWLTLRGGKGFL---F 480
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPGLPvtnF 80
                           90       100       110
                   ....*....|....*....|....*....|.
gi 2462622953  481 TVADLQAGVVRYHHDDSDSTKDFVVFRIFDG 511
Cdd:pfam16184   81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1267-1383 4.52e-29

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 112.70  E-value: 4.52e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953 1267 HKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKiGRDWVPLSp 1346
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALK-GAPGLPVT- 78
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2462622953 1347 gmKCTQEEVDLNLLRYTHTGamDSQNQDSFTFYLWDG 1383
Cdd:pfam16184   79 --NFTQADIDSGLVVYVHDG--SESTSDGFTFQVTDG 111
Frem_N pfam19309
Frem protein N-terminal domain; This entry represents a presumed domain found at the ...
29-269 3.57e-28

Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.


Pssm-ID: 466034  Cd Length: 202  Bit Score: 113.19  E-value: 3.57e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953   29 NRGVRVMKGHSAFLSG-DDLKFAIPKeKDACKVEVVMNEPITQRVGKLTPQVFDCHFLPNEVKYVHNGCPILDEDTVKLR 107
Cdd:pfam19309    5 NRGLRVPFGRSVWLDPlRDLVIQVQP-GDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRVRLQ 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  108 LYRFTERDTFIETFILWVYLLEPDCNIIhMSNNVLEVPEFNGLSQAIDKNLLRFDYDRmASLECTVSLDTARTRLPAHGQ 187
Cdd:pfam19309   84 LRYDAPTDTLVLPFTLEVEVVFSQLEIV-TRNLPLTVEKLLGTSNPIDRRVLEFAYDP-GTERCKVTVLPGAGGLPRYGR 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  188 MVlgeprpeeprgdqphsffpesrmmsfNAflelraklkcpggsctPGLkkigSLKVSCEEFLLMGLRYQHL-DPPSPNI 266
Cdd:pfam19309  162 LV--------------------------NA----------------TGA----PLMVDCEAFLRAGVRYQHTaTTSSPNR 195

                   ...
gi 2462622953  267 DYI 269
Cdd:pfam19309  196 DYV 198
Cadherin_3 pfam16184
Cadherin-like;
513-625 2.77e-27

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 107.30  E-value: 2.77e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  513 HSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITKPPQAGEIMKKPGPGLigyPV 592
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL---PV 77
                           90       100       110
                   ....*....|....*....|....*....|...
gi 2462622953  593 HGFLQRDLFNGIIYYRHFGGEIFEDSFQFVLWD 625
Cdd:pfam16184   78 TNFTQADIDSGLVVYVHDGSESTSDGFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
775-878 1.72e-23

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 96.52  E-value: 1.72e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  775 FNITILPVDNQVPEAFTN-PLKVTEGGQSIISTEHILIYDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLH 853
Cdd:pfam16184    7 FNITIIPVNDEAPVLTTNtGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQADID 86
                           90       100
                   ....*....|....*....|....*
gi 2462622953  854 TLKVRYQHDGTEVLQDDLLLEVTDG 878
Cdd:pfam16184   87 SGLVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1140-1265 5.50e-23

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 94.98  E-value: 5.50e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953 1140 HSLEIPFSIIINPTNDEAPDfVVQN--ITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLidrgfskdfsen 1217
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPV-LTTNtgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHL------------ 67
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2462622953 1218 kqpANPHQKHAPVHSFSMELLKTGmRLTYMHDDSESLADDFTIQLSDG 1265
Cdd:pfam16184   68 ---ALKGAPGLPVTNFTQADIDSG-LVVYVHDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
1016-1137 6.30e-23

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 94.98  E-value: 6.30e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953 1016 SFPVYdLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENilpsvgfeKSN 1095
Cdd:pfam16184    2 SVPFT-FNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGA 72
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 2462622953 1096 IGISIDSFQWKDMNAFHINYVqsrHLRIEPTADQFTVYVTDG 1137
Cdd:pfam16184   73 PGLPVTNFTQADIDSGLVVYV---HDGSESTSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
880-993 2.45e-18

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 81.88  E-value: 2.45e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  880 NSAEFVLHVEVFPVNDEPPVLKADlmPVMNCSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHG---VVRRAGVTVD 956
Cdd:pfam16184    1 RSVPFTFNITIIPVNDEAPVLTTN--TGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGhlaLKGAPGLPVT 78
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2462622953  957 QFSQRDVISEAVTYKHTGGEiglmPCFDTITLVVSDG 993
Cdd:pfam16184   79 NFTQADIDSGLVVYVHDGSE----STSDGFTFQVTDG 111
Cadherin_3 pfam16184
Cadherin-like;
633-764 3.53e-10

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 58.77  E-value: 3.53e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462622953  633 SVPQVATIHITPVDDqlpkEAPGVSRH--LVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPffsfSHRHLdagklf 710
Cdd:pfam16184    2 SVPFTFNITIIPVND----EAPVLTTNtgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP----SHGHL------ 67
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2462622953  711 mvdsipkVVKNPTALELRSFTQHAVNYMKVAYM----PPMQDigphcrdvQFTFSVSN 764
Cdd:pfam16184   68 -------ALKGAPGLPVTNFTQADIDSGLVVYVhdgsESTSD--------GFTFQVTD 110
Cadherin_3 pfam16184
Cadherin-like;
324-400 8.47e-07

Cadherin-like;


Pssm-ID: 465048 [Multi-domain]  Cd Length: 111  Bit Score: 49.14  E-value: 8.47e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462622953  324 LTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTWKDLSDMQIAYQppnSSHSERRHDEVELEVYD 400
Cdd:pfam16184   37 ITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV---HDGSESTSDGFTFQVTD 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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