|
Name |
Accession |
Description |
Interval |
E-value |
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
89-325 |
1.70e-101 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 299.21 E-value: 1.70e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 89 LDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDvpge 168
Cdd:cd19491 1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQLALTVQLPRELGGLGGGAVYICTESSFPSKRLQQLASSLPKRYHL---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 169 lLQKLRFGSQIFIEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFD--SQASAPRARHLQSLGAMLRELS 246
Cdd:cd19491 77 -EKAKNFLDNIFVEHVADLETLEHCLNYQLPALLERGPIRLVVIDSIAALFRSEFDtsRSDLVERAKYLRRLADHLKRLA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 247 SAFQSPVLCINQVTEAMEEQGAA-------------HGPLGFWDERVSPALGITWANQLLVRLLADRLREE---EAALGC 310
Cdd:cd19491 156 DKYNLAVVVVNQVTDRFDSSSDAsglgvldylsqfsSFSGGVSGNRKVPALGLTWANLVNTRLMLSRTPKRitdSSAASI 235
|
250
....*....|....*
gi 2462541566 311 PARTLRVLSAPHLPP 325
Cdd:cd19491 236 SVRRLEVVFSPHLPP 250
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
100-300 |
1.82e-54 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 176.77 E-value: 1.82e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 100 DGITELAGRSSAGKTQLALQLCLAVQFprqhggLEAGAVYICTEDAFPHKRLQQLMAQqprlrtdVPGELLQKLRFGSQI 179
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALL------LGGGVVWIDTEGAFPPSRLVQILEA-------SPSSELELAEALSRL 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 180 FIEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQ-----ASAPRARHLQSLGAMLRELSSAFQSPVL 254
Cdd:cd01393 68 LYFRPPDTLAHLLALDSLPESLFPPPNTSLVVVDSVSALFRKAFPRGgdgdsSSSLRARLLSQLARALQKLAAQFNLAVV 147
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2462541566 255 CINQVTEAMEEqgaahgplGFWDERVSPALGITWANQLLVRLLADR 300
Cdd:cd01393 148 VTNQVTTKIRG--------GSGASLVPPALGNTWEHSVSTRLLLYR 185
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
90-305 |
9.63e-35 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 126.67 E-value: 9.63e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 90 DALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQlMAQQPRLRTD----- 164
Cdd:cd19493 1 DTALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKGGLDGGVLYIDTESKFSAERLAE-IAEARFPEAFsgfme 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 165 ---VPGELLQKLRfgsqifIEHVADVDTLLECV-NKKVPVLLSRgmARLVVIDSVAAPFRCEFDSQASAPRARH--LQSL 238
Cdd:cd19493 80 eneRAEEMLKRVA------VVRVTTLAQLLERLpNLEEHILSSG--VRLVVIDSIAALVRREFGGSDGEVTERHnaLARE 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462541566 239 GAMLRELSSAFQSPVLCINQVTEAMEEQGAAHGPLGfwdervsPALGITWANQLLVRLLADRLREEE 305
Cdd:cd19493 152 ASSLKRLAEEFRIAVLVTNQATTHFGDAGDGSSGVT-------AALGDAWAHAVNTRLRLERCLLQL 211
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
64-337 |
2.35e-33 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 123.95 E-value: 2.35e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 64 TALQLHQQKERFptqhQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTE 143
Cdd:pfam08423 5 TATELHQRRSEL----IQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 144 DAFPHKRLQQLmAQqpRLRTDvPGELLQKLRFGSQIFIEHVADvdtLLEcvnkKVPVLLSRGMARLVVIDSVAAPFRCEF 223
Cdd:pfam08423 81 GTFRPERLVAI-AE--RYGLD-PEDVLDNVAYARAYNSEHQMQ---LLQ----QAAAMMSESRFALLIVDSATALYRTDF 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 224 DSQAS-APRARHLQSLGAMLRELSSAFQSPVLCINQVTEAMEEQGAAHGPlgfwDERvSPALGITWANQLLVRLLADRLR 302
Cdd:pfam08423 150 SGRGElAERQQHLAKFLRTLQRLADEFGVAVVITNQVVAQVDGAAGMFSG----DPK-KPIGGHIMAHASTTRLSLRKGR 224
|
250 260 270
....*....|....*....|....*....|....*
gi 2462541566 303 EEEaalgcpaRTLRVLSAPHLPPSSCSYTISAEGV 337
Cdd:pfam08423 225 GEQ-------RICKIYDSPCLPESEAVFAIGSGGI 252
|
|
| recomb_radA |
TIGR02236 |
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
81-338 |
7.74e-31 |
|
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 118.69 E-value: 7.74e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 81 RLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQlMAQQPR 160
Cdd:TIGR02236 76 KITTGSKELDELLGGGIETQAITEVFGEFGSGKTQICHQLAVNVQLPEEKGGLGGKAVYIDTENTFRPERIMQ-MAEARG 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 161 LRTDvpgELLQKLRFGSQIFIEH-VADVDTLLECVNK-KVPVllsrgmaRLVVIDSVAAPFRCEFDSQAS-APRARHLQS 237
Cdd:TIGR02236 155 LDPD---EVLKNIYVARAYNSNHqMLLVEKAEDLIKElNNPV-------KLLIVDSLTSHFRAEYVGRGAlAERQQKLNK 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 238 LGAMLRELSSAFQSPVLCINQVTEAmeeqgaahgPLGFWDERVSPALGITWANQLLVRLLADRLREEEaalgcpaRTLRV 317
Cdd:TIGR02236 225 HLHDLLRLADLYNAAVVVTNQVMAR---------PDAFFGDPTRPIGGHILGHAATFRVYLRKGKGDK-------RIARL 288
|
250 260
....*....|....*....|.
gi 2462541566 318 LSAPHLPPSSCSYTISAEGVR 338
Cdd:TIGR02236 289 VDSPHLPEGEAVFRITEKGIE 309
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
64-338 |
6.38e-30 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 116.13 E-value: 6.38e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 64 TALQLHQQKErfptQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTE 143
Cdd:PRK04301 70 TALEVLERRK----NVGKITTGSKELDELLGGGIETQSITEFYGEFGSGKTQICHQLAVNVQLPEEKGGLEGKAVYIDTE 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 144 DAFPHKRLQQlMAQqpRLRTDvPGELLQKLR----FGS--QIFIehvadVDTLLECVNKKVPVllsrgmaRLVVIDSVAA 217
Cdd:PRK04301 146 GTFRPERIEQ-MAE--ALGLD-PDEVLDNIHvaraYNSdhQMLL-----AEKAEELIKEGENI-------KLVIVDSLTA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 218 PFRCEFDSQAS-APR----ARHLqslgAMLRELSSAFQSPVLCINQVteameeqgaAHGPLGFWDERVSPALGITWANQL 292
Cdd:PRK04301 210 HFRAEYVGRGNlAERqqklNKHL----HDLLRLADLYNAAVVVTNQV---------MARPDAFFGDPTQPIGGHILGHTA 276
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 2462541566 293 LVRLLADRLREEEaalgcpaRTLRVLSAPHLPPSSCSYTISAEGVR 338
Cdd:PRK04301 277 TFRIYLRKSKGNK-------RIARLVDSPHLPEGEAVFRITEEGIR 315
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
102-297 |
1.74e-29 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 111.16 E-value: 1.74e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 102 ITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFphkrlqqlmaqqprlrtdvpgellqklrfgsQIFI 181
Cdd:cd19492 3 ITEICGVPGVGKTQLCMQLAVNVQIPKCFGGLAGEAIYIDTEGSF-------------------------------NIHY 51
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 182 EHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSqaSAPRARHLQSLGAMLRELSSAFQSPVLCINQVTE 261
Cdd:cd19492 52 FRVHDYVELLALINSLPKFLEDHPKVKLIVVDSIAFPFRHDFDD--LAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTT 129
|
170 180 190
....*....|....*....|....*....|....*.
gi 2462541566 262 AMEEQGAAHgplgfwderVSPALGITWANQLLVRLL 297
Cdd:cd19492 130 KISEDGQSQ---------LVPALGESWSHACTTRLF 156
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
82-338 |
8.81e-28 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 108.60 E-value: 8.81e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 82 LSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQlMAQQPRL 161
Cdd:cd19515 1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPPEEGGLNGKAVYIDTENTFRPERIMQ-MAKALGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 162 RtdvPGELLQKLRFGSQIFIEH-VADVDTLLECVNKKVPVllsrgmaRLVVIDSVAAPFRCEFDSQAS-APRARHLQSLG 239
Cdd:cd19515 80 D---PDEVLDNIYVARAYNSNHqMLLVEKAEDLIKEGNNI-------KLLIVDSLTSHFRAEYVGRGTlAERQQKLNKHL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 240 AMLRELSSAFQSPVLCINQVTEAmeeqgaahgPLGFWDERVSPALGITWANQLLVRLLadrLREEEAALgcpaRTLRVLS 319
Cdd:cd19515 150 HDLHRLADLYNIAVLVTNQVMAK---------PDAFFGDPTQAIGGHILGHAATFRVY---LRKGKGGK----RIARLVD 213
|
250
....*....|....*....
gi 2462541566 320 APHLPPSSCSYTISAEGVR 338
Cdd:cd19515 214 SPHLPEGEAVFRITEKGIE 232
|
|
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
2-337 |
7.23e-26 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 105.25 E-value: 7.23e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 2 DLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASlHLRGSSILTALQLHQQKERFptqhQR 81
Cdd:TIGR02238 3 KLQAHGINAADIKKLKSAGICTVNGVIMTTRRALCKIKGLSEAKVDKIKEAAS-KIINPGFITAFEISQKRKKV----LK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 82 LSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLmaqQPRL 161
Cdd:TIGR02238 78 ITTGSQALDGILGGGIESMSITEVFGEFRCGKTQLSHTLCVTAQLPREMGGGNGKVAYIDTEGTFRPDRIRAI---AERF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 162 RTDvPGELLQKLRFGSQIFIEHvaDVDTLLECVNKkvpvlLSRGMARLVVIDSVAAPFRCEFDSQAS-APRARHLQSLGA 240
Cdd:TIGR02238 155 GVD-PDAVLDNILYARAYTSEH--QMELLDYLAAK-----FSEEPFRLLIVDSIMALFRVDFSGRGElSERQQKLAQMLS 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 241 MLRELSSAFQSPVLCINQVteaMEEQGAAhgpLGFWDERVSPALGITWANQLLVRLLADRLREEEaalgcpaRTLRVLSA 320
Cdd:TIGR02238 227 RLNKISEEFNVAVFVTNQV---QADPGAT---MTFIADPKKPIGGHVLAHASTTRILLRKGRGEE-------RVAKLYDS 293
|
330
....*....|....*..
gi 2462541566 321 PHLPPSSCSYTISAEGV 337
Cdd:TIGR02238 294 PDMPEAEASFQITEGGI 310
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
82-337 |
3.33e-24 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 98.97 E-value: 3.33e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 82 LSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLmAQqpRL 161
Cdd:cd19514 1 ISTGSTELDKLLGGGIESMSITEVFGEFRTGKTQLSHTLCVTAQLPGSMGGGGGKVAYIDTEGTFRPDRIRPI-AE--RF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 162 RTDvPGELLQKLRFGSQIFIEHVADvdtLLECVNKKvpvLLSRGMARLVVIDSVAAPFRCEFDSQAS-APRARHLQSLGA 240
Cdd:cd19514 78 GVD-HDAVLDNILYARAYTSEHQME---LLDYVAAK---FHEEAVFRLLIIDSIMALFRVDFSGRGElAERQQKLAQMLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 241 MLRELSSAFQSPVLCINQVTE----AMEEQGAAHGPLGfwdervspalGITWANQLLVRLLADRLREEEaalgcpaRTLR 316
Cdd:cd19514 151 RLQKISEEYNVAVFITNQVTAdpgaAMTFQADPKKPIG----------GHILAHASTTRISLRKGRGEE-------RIAK 213
|
250 260
....*....|....*....|.
gi 2462541566 317 VLSAPHLPPSSCSYTISAEGV 337
Cdd:cd19514 214 IYDSPDLPENEATFAITAGGI 234
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
13-338 |
5.76e-24 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 100.58 E-value: 5.76e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 13 IAA--IKK---AKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASlHLRGSSILTALQLHQQKErfptQHQRLSLGCP 87
Cdd:PLN03186 36 IAAldIKKlkdAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEAAS-KLVPLGFTTASQLHAQRQ----EIIQITTGSR 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 88 VLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAqqprlrtdvpg 167
Cdd:PLN03186 111 ELDKILEGGIETGSITEIYGEFRTGKTQLCHTLCVTCQLPLDQGGGEGKAMYIDTEGTFRPQRLIQIAE----------- 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 168 ellqklRFG--SQIFIEHVA-----DVDTLLECVNKKVPVLLSRGMArLVVIDSVAAPFRCEFDSQAS-APRARHLQSLG 239
Cdd:PLN03186 180 ------RFGlnGADVLENVAyarayNTDHQSELLLEAASMMAETRFA-LMIVDSATALYRTEFSGRGElSARQMHLGKFL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 240 AMLRELSSAFQSPVLCINQVTEAMEeqGAAHgplgFWDERVSPALGITWANQLLVRLLADRLREEEaalgcpaRTLRVLS 319
Cdd:PLN03186 253 RSLQRLADEFGVAVVITNQVVAQVD--GSAF----FAGPQLKPIGGNIMAHASTTRLALRKGRGEN-------RICKVIS 319
|
330
....*....|....*....
gi 2462541566 320 APHLPPSSCSYTISAEGVR 338
Cdd:PLN03186 320 SPCLPEAEARFSISSEGVT 338
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
82-337 |
1.24e-23 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 97.22 E-value: 1.24e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 82 LSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLmAQQPRL 161
Cdd:cd01123 1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAIYIDTEGTFRPERLRAI-AQRFGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 162 RtdvPGELLQKLRFGSQIFIEHVADvdtLLECVNKKvpvlLSRGMARLVVIDSVAAPFRCEFDSQAS-APRARHLQSLGA 240
Cdd:cd01123 80 D---PDDVLDNVAYARAFNSDHQTQ---LLDQAAAM----MVESRFKLLIVDSATALYRTDYSGRGElSARQMHLAKFLR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 241 MLRELSSAFQSPVLCINQVTEAMEeqgaahGPLGFWDERVSPALGITWANQLLVRLLADRLREEEaalgcpaRTLRVLSA 320
Cdd:cd01123 150 MLQRLADEFGVAVVVTNQVVAQVD------GAMMFAADPKKPIGGNILAHASTTRLYLRKGRGET-------RICKIYDS 216
|
250
....*....|....*..
gi 2462541566 321 PHLPPSSCSYTISAEGV 337
Cdd:cd01123 217 PCLPEAEAVFAITADGV 233
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
8-337 |
1.29e-23 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 99.30 E-value: 1.29e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 8 LNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASlHLRGSSILTALQLHQQKERFptqhQRLSLGCP 87
Cdd:PTZ00035 31 INAADIKKLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAAS-KLVPMGFISATEYLEARKNI----IRITTGST 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 88 VLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLmAQqprlrtdvpg 167
Cdd:PTZ00035 106 QLDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDTEGTFRPERIVQI-AE---------- 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 168 ellqklRFG-------SQIFIEHVADVDTLLECVNkKVPVLLSRGMARLVVIDSVAAPFRCEFDSQAS-APRARHLQSLG 239
Cdd:PTZ00035 175 ------RFGldpedvlDNIAYARAYNHEHQMQLLS-QAAAKMAEERFALLIVDSATALFRVDYSGRGElAERQQHLGKFL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 240 AMLRELSSAFQSPVLCINQVteaMEEQGAAhgpLGFWDERVSPALGITWANQLLVRLLADRLREEEaalgcpaRTLRVLS 319
Cdd:PTZ00035 248 RALQKLADEFNVAVVITNQV---MADVDGA---SMFVADPKKPIGGHIIAHASTTRLSLRKGRGEQ-------RICKIYD 314
|
330
....*....|....*...
gi 2462541566 320 APHLPPSSCSYTISAEGV 337
Cdd:PTZ00035 315 SPNLPESEAVFAISEGGI 332
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
13-337 |
2.70e-23 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 98.70 E-value: 2.70e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 13 IAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHLRGSSILTALQLHQQKERFptqhqRLSLGCPVLDAL 92
Cdd:PLN03187 44 VKKLQDAGIYTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAEKLLNQGFITGSDALLKRKSVV-----RITTGSQALDEL 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 93 LRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAqqpRLRTDvPGELLQK 172
Cdd:PLN03187 119 LGGGIETRCITEAFGEFRSGKTQLAHTLCVTTQLPTEMGGGNGKVAYIDTEGTFRPDRIVPIAE---RFGMD-ADAVLDN 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 173 LRFGSQIFIEHVADVDTLLECVNKKVPVllsrgmaRLVVIDSVAAPFRCEFDSQAS-APRARHLQSLGAMLRELSSAFQS 251
Cdd:PLN03187 195 IIYARAYTYEHQYNLLLGLAAKMAEEPF-------RLLIVDSVIALFRVDFTGRGElAERQQKLAQMLSRLTKIAEEFNV 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 252 PVLCINQVTeameeqgAAHGPLGFWDERVSPALGITWANQLLVRLLADRLREEeaalgcpARTLRVLSAPHLPPSSCSYT 331
Cdd:PLN03187 268 AVYMTNQVI-------ADPGGGMFISDPKKPAGGHVLAHAATIRLMLRKGKGE-------QRVCKVFDAPNLPEAEAEFQ 333
|
....*.
gi 2462541566 332 ISAEGV 337
Cdd:PLN03187 334 ITSGGI 339
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
94-301 |
1.22e-19 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 85.77 E-value: 1.22e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 94 RGGLPLDGITELAGRSSAGKTQLAlqLCLAVQFPRQHGgleAGAVYICTEDAFPHKRLQQlMAQQPRLRTDVPGELLQKL 173
Cdd:cd19489 1 GGGLRTGEITELVGESSSGKTQLC--LTAAANVASRSG---QNVLYIDTKSSFSARRLAQ-ILKSRAQDAEEIDKALQRI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 174 RFgSQIF-IEHVAD-VDTLLECVNKKVPVLLSRgmARLVVIDSVAAPFRCEFDS-QASAPRArHLQSLGAMLRELSSAFQ 250
Cdd:cd19489 75 RV-VRVFdPYELLDlLEELRNTLSQQQENLYSR--LKLVIIDSLSALISPLLGGsKHSEGHA-LLASLARLLKKLAAEYQ 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2462541566 251 SPVLCINQVTeameeqgaaHGPLGFWDERVSPALGITWANQLLVRLLADRL 301
Cdd:cd19489 151 IAVLVTNLTV---------RGGDGGQQGSTKPALGEYWESVPSTRLLLSRD 192
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
82-337 |
1.32e-19 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 86.22 E-value: 1.32e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 82 LSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLmAQQPRL 161
Cdd:cd19513 1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAI-AERYGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 162 RtdvPGELLQKLRFGSQIFIEHVADVdtLLECVNkkvpvLLSRGMARLVVIDSVAAPFRCEFDSQAS-APRARHLQSLGA 240
Cdd:cd19513 80 N---GEDVLDNVAYARAYNTDHQMQL--LIQASA-----MMAESRYALLIVDSATALYRTDYSGRGElSARQMHLAKFLR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 241 MLRELSSAFQSPVLCINQVTE----AMEEQGAAHGPLGfwdervspalGITWANQLLVRLLADRLREEEaalgcpaRTLR 316
Cdd:cd19513 150 MLQRLADEFGVAVVITNQVVAqvdgAAMFAGDPKKPIG----------GNIMAHASTTRLYLRKGRGET-------RICK 212
|
250 260
....*....|....*....|.
gi 2462541566 317 VLSAPHLPPSSCSYTISAEGV 337
Cdd:cd19513 213 IYDSPCLPEAEAVFAITEDGI 233
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
8-337 |
3.60e-19 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 86.70 E-value: 3.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 8 LNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASlHLRGSSILTALQLHQQKERFPTqhqrLSLGCP 87
Cdd:TIGR02239 9 ITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAA-KLVPMGFTTATEFHQRRQEVIQ----LTTGSK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 88 VLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFphkRLQQLMAQQPRLRTDvPG 167
Cdd:TIGR02239 84 ELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTF---RPERLLAIAERYGLN-PE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 168 ELLQKLRFGSQIFIEHvaDVDTLLECVNkkvpvLLSRGMARLVVIDSVAAPFRCEFDSQAS-APRARHLQSLGAMLRELS 246
Cdd:TIGR02239 160 DVLDNVAYARAYNTDH--QLQLLQQAAA-----MMSESRFALLIVDSATALYRTDFSGRGElSARQMHLARFLRSLQRLA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 247 SAFQSPVLCINQVTEAMEEQGAAhgplgFWDERVSPALGITWANQLLVRLLADRLREEEaalgcpaRTLRVLSAPHLPPS 326
Cdd:TIGR02239 233 DEFGVAVVITNQVVAQVDGAGSM-----FAGDPKKPIGGNIMAHASTTRLSLRKGRGEQ-------RICKIYDSPCLPES 300
|
330
....*....|.
gi 2462541566 327 SCSYTISAEGV 337
Cdd:TIGR02239 301 EAMFAIYEDGI 311
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
82-259 |
9.34e-13 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 66.57 E-value: 9.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 82 LSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQlcLAVQFPRQHGgleaGAVYICTEdAFPHKRLQQLMAqqprl 161
Cdd:cd01394 1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKTNICLQ--LAVEAAKQGK----KVVYIDTE-GLSPERFQQIAG----- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 162 rtDVPGELLqklrfgSQIFIEHVADVDTLLECVNkKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASAPR--ARHLQSLG 239
Cdd:cd01394 69 --ERFESIA------SNIIVFEPYSFDEQGVAIQ-EAEKLLKSDKVDLVVVDSATALYRLELGDDSEANRelSRQMSKLL 139
|
170 180
....*....|....*....|
gi 2462541566 240 AMLRElssaFQSPVLCINQV 259
Cdd:cd01394 140 SIARK----YDIPVVITNQV 155
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
81-338 |
7.24e-11 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 61.08 E-value: 7.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 81 RLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAvqfprqhgGLEAG--AVYICTEDafphkRLQQLMAQQ 158
Cdd:COG0467 1 RVPTGIPGLDELLGGGLPRGSSTLLSGPPGTGKTTLALQFLAE--------GLRRGekGLYVSFEE-----SPEQLLRRA 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 159 PRLRTDVpGELLQ--KLRFGSQIFIEHVADVDTLLEcvnkKVPVLLSRGMARLVVIDSVAApFRCEFDSQASAprARHLQ 236
Cdd:COG0467 68 ESLGLDL-EEYIEsgLLRIIDLSPEELGLDLEELLA----RLREAVEEFGAKRVVIDSLSG-LLLALPDPERL--REFLH 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 237 SLGAMLRELssafQSPVLCINQVTEAMEEqgAAHGPLGFwdervspalgitwanqllvrlLAD---RLREEEAAlGCPAR 313
Cdd:COG0467 140 RLLRYLKKR----GVTTLLTSETGGLEDE--ATEGGLSY---------------------LADgviLLRYVELG-GELRR 191
|
250 260
....*....|....*....|....*...
gi 2462541566 314 TLRVL---SAPHlPPSSCSYTISAEGVR 338
Cdd:COG0467 192 ALSVLkmrGSAH-DRTIREFEITDGGIE 218
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
81-259 |
3.32e-10 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 59.49 E-value: 3.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 81 RLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQlcLAVQFPRQhGGLeagAVYICTEDAFPhKRLQQLMAQQPR 160
Cdd:PRK09361 4 RLPTGCKMLDELLGGGFERGTITQIYGPPGSGKTNICLQ--LAVEAAKN-GKK---VIYIDTEGLSP-ERFKQIAGEDFE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 161 lrtdvpgELLQKlrfgsqIFIEHVADVDTLLECVNKKVPVLLSRgmARLVVIDSVAAPFRCEFDSQASAPRA-RHLQSLG 239
Cdd:PRK09361 77 -------ELLSN------IIIFEPSSFEEQSEAIRKAEKLAKEN--VGLIVLDSATSLYRLELEDEEDNSKLnRELGRQL 141
|
170 180
....*....|....*....|
gi 2462541566 240 AMLRELSSAFQSPVLCINQV 259
Cdd:PRK09361 142 THLLKLARKHDLAVVITNQV 161
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
87-256 |
3.21e-08 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 53.15 E-value: 3.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 87 PVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAV----QFPRQHGGLEAGAV-YICTEDAFP--HKRLQQLMAQQP 159
Cdd:pfam13481 20 PPRRWLIKGLLPAGGLGLLAGAPGTGKTTLALDLAAAVatgkPWLGGPRVPEQGKVlYVSAEGPADelRRRLRAAGADLD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 160 RLR----TDVPGEL-LQKLRFGSQIFIEHVADVDTLLEcvnkkvpvllSRGMARLVVIDSVAAPFRcefdsqASAPRARH 234
Cdd:pfam13481 100 LPArllfLSLVESLpLFFLDRGGPLLDADVDALEAALE----------EVEDPDLVVIDPLARALG------GDENSNSD 163
|
170 180
....*....|....*....|..
gi 2462541566 235 LQSLGAMLRELSSAFQSPVLCI 256
Cdd:pfam13481 164 VGRLVKALDRLARRTGATVLLV 185
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
89-217 |
5.35e-07 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 50.67 E-value: 5.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 89 LDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAV-------QFPRQHGgleaGAVYICTEDAFP--HKRLQQLMAQQP 159
Cdd:COG3598 2 RRWLVPGLLPEGGVTLLAGPPGTGKSFLALQLAAAVaaggpwlGRRVPPG----KVLYLAAEDDRGelRRRLKALGADLG 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462541566 160 RLRTDVPGELLqkLRFGSQIFIeHVADVDTLLEcvnkkvpvLLSRGMARLVVIDSVAA 217
Cdd:COG3598 78 LPFADLDGRLR--LLSLAGDLD-DTDDLEALER--------AIEEEGPDLVVIDPLAR 124
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
82-261 |
1.03e-06 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 49.09 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 82 LSLGCPVLDALLR-GGLPLDGITELAGRSSAGKTQLALQLCLAVQfprQHGGLeagAVYICTEDAF-PH--KRL----QQ 153
Cdd:cd00983 5 IPTGSLSLDIALGiGGLPRGRIIEIYGPESSGKTTLALHAIAEAQ---KLGGT---AAFIDAEHALdPEyaKKLgvdiDN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 154 LMAQQPrlrtdvpgellqklRFGSQifiehvadvdtLLECVNkkvpVLLSRGMARLVVIDSVAA--PfRCEFDSQASApR 231
Cdd:cd00983 79 LLVSQP--------------DTGEQ-----------ALEIAD----TLIRSGAVDLIVVDSVAAlvP-KAEIEGEMGD-S 127
|
170 180 190
....*....|....*....|....*....|....*
gi 2462541566 232 ARHLQS--LGAMLRELSSAF---QSPVLCINQVTE 261
Cdd:cd00983 128 HVGLQArlMSQALRKLTGSLsksKTTVIFINQLRE 162
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
102-258 |
1.43e-06 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 48.50 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 102 ITELAGRSSAGKTQLALQLCLAVQFPRQH-----GGLEAGAVYICTEDAFPHKRLQQLMAQqpRLRTDVPGELLQKLRFG 176
Cdd:cd19490 3 VIEITGPSGSGKTELLYHLAARCILPSSWggvplGGLEAAVVFIDTDGRFDILRLRSILEA--RIRAAIQAANSSDDEED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 177 SQIFIE------HVADVDTLLE--CVNKKVPVLLSRGMA----RLVVIDSVAAPF---RCEFDSQASAPRARH--LQSLG 239
Cdd:cd19490 81 VEEIAReclqrlHIFRCHSSLQllATLLSLENYLLSLSAnpelGLLLIDSISAFYwqdRFSAELARAAPLLQEaaLRAIL 160
|
170
....*....|....*....
gi 2462541566 240 AMLRELSSAFQSPVLCINQ 258
Cdd:cd19490 161 RELRRLRRRFQLVVIATKQ 179
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
82-245 |
5.88e-06 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 46.87 E-value: 5.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 82 LSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLClavqfprqHGGLEAG--AVYICTEDafphkRLQQLMAQQP 159
Cdd:cd01124 1 VKTGIPGLDELLGGGIPKGSVTLLTGGPGTGKTLFGLQFL--------YAGAKNGepGLFFTFEE-----SPERLLRNAK 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 160 RLRTDV-PGELLQKLRFGSQIFIEHV-ADVDTLLECVNKKVPvllSRGMARlVVIDSVAAPFRcefdSQASAPRAR-HLQ 236
Cdd:cd01124 68 SFGWDFdEMEDEGKLIIVDAPPTEAGrFSLDELLSRILSIIK---SFKAKR-VVIDSLSGLRR----AKEDQMRARrIVI 139
|
....*....
gi 2462541566 237 SLGAMLREL 245
Cdd:cd01124 140 ALLNELRAA 148
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
85-217 |
2.57e-05 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 45.55 E-value: 2.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 85 GCPVLDALL-RGGLPLDGITELAGRSSAGKTQLALQLCLAVQfprQHGGLeagAVYICTEDAFPHKRlqqlmAQqpRLRT 163
Cdd:COG0468 47 GSLALDIALgVGGLPRGRIVEIYGPESSGKTTLALHAIAEAQ---KAGGI---AAFIDAEHALDPEY-----AK--KLGV 113
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462541566 164 DVpGELLqklrfgsqifiehVADVDT---LLECVNKkvpvLLSRGMARLVVIDSVAA 217
Cdd:COG0468 114 DI-DNLL-------------VSQPDTgeqALEIAET----LVRSGAVDLIVVDSVAA 152
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
85-217 |
4.65e-03 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 38.00 E-value: 4.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 85 GCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQlcLAVQFPRQHGglEAGaVYICTEDafPHKRLQQLMAQQprlrtd 164
Cdd:pfam06745 4 GIPGLDEILKGGFPEGRVVLITGGPGTGKTIFGLQ--FLYNGALKYG--EPG-VFVTLEE--PPEDLRENARSF------ 70
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462541566 165 vpGELLQKLRFGSQIFIEHVADVDTLLECV--NKKVPVLLSRGM-------ARLVVIDSVAA 217
Cdd:pfam06745 71 --GWDLEKLEEEGKLAIIDASTSGIGIAEVedRFDLEELIERLReaireigAKRVVIDSITT 130
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
77-215 |
4.68e-03 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 38.28 E-value: 4.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 77 TQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQfprQHGGLeagAVYICTEDAfphkrlqqlmA 156
Cdd:cd01121 59 EEEERISTGIGELDRVLGGGLVPGSVVLIGGDPGIGKSTLLLQVAARLA---QRGGK---VLYVSGEES----------L 122
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462541566 157 QQPRLRTDvpgellqklRFG---SQIFIEHVADVDTLLECVNKKVPvllsrgmaRLVVIDSV 215
Cdd:cd01121 123 SQIKLRAE---------RLGlgsDNLYLLAETNLEAILAEIEELKP--------SLVVIDSI 167
|
|
| RepA_RSF1010_like |
cd01125 |
Hexameric Replicative Helicase RepA of plasmid RSF1010 and related proteins; This family ... |
101-232 |
5.06e-03 |
|
Hexameric Replicative Helicase RepA of plasmid RSF1010 and related proteins; This family includes the homo-hexameric replicative helicase RepA encoded by plasmid RSF1010. RSF1010 is found in most Gram-negative bacteria and some Gram-positive bacteria . The RepA protein of Plasmid RSF1010 is a 5'-3' DNA helicase which can utilize ATP, dATP, GTP and dGTP (and CTP and dCTP to a lesser extent).
Pssm-ID: 410870 Cd Length: 238 Bit Score: 38.13 E-value: 5.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462541566 101 GITELAGRSSAGKTQLALQLCLAVQ-------FPRQHGGleaGAVYICTEDAFP--HKRLQQLMAQQPRLRTDVPGELLQ 171
Cdd:cd01125 2 TLGMLVGPPGSGKSFLALDLAVAVAtgrdwlgERRVKQG---RVVYLAAEDPRDglRRRLKAIGAHLGDEDAALAENLVI 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462541566 172 K-LRFGSQIFIEHVADVDTLLECVnkkvpvllsrGMARLVVIDSVAapfRCEFDSQASAPRA 232
Cdd:cd01125 79 EnLRGKPVSIDAEAPELERIIEEL----------EGVRLIIIDTLA---RVLHGGDENDAAD 127
|
|
| |
