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Conserved domains on  [gi|2462544982|ref|XP_054234342|]
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protein Lines homolog 1 isoform X4 [Homo sapiens]

Protein Classification

BLUF domain-containing protein( domain architecture ID 10631370)

BLUF domain-containing protein similar to Rhodobacter sphaeroides transcriptional antirepressor AppA that senses both the light climate and the intracellular redox state

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LINES_N pfam14694
Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this ...
1-293 0e+00

Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this protein is involved in embryonic segmentation and may function as a transcriptional regulator.


:

Pssm-ID: 464266  Cd Length: 351  Bit Score: 524.57  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544982   1 MCFLDLLELLIASRIHLKLHFTCQRILFLKPSCMLEVITWPIQAFVKRKVIIFLKKCLLCKVGEDLCRGSVPALMPPDHH 80
Cdd:pfam14694  58 ISFLDLLELLIASRINLSLHFICQRPLFLKLSCFLDLLNSPVPYFVKKKLILLLKKCLLYKSGEDLCRGSVPATLALDDM 137
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544982  81 VAVDMLALANAVLQAVNSGLLKTLSVYEKHSFFGGDEVQPECELITSPDHVILRAASLVIMKSLEIKFQNYSSASEMKVD 160
Cdd:pfam14694 138 LDEDMLALAHAVLQAVDLGLLDSLPVRGKPSRFGGSEVQPGCGGRGGPDHVLLRAASLLVLKSLEIKVQETRSASEIKRS 217
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544982 161 LQRFMSELLTFLKPHLQPSLQ-LHNPCKWLSRVFIEQDDDMLEAAKASLGIYLTLTRGCEATESLTQGKEMWDHHTHENG 239
Cdd:pfam14694 218 LQRVMSELLTFLKQHLPPQFHpETHPCEWLSRVFIEQDDDMLEAAKALLDIYLGLTRRHEATPSLSQEKESWNHHTHENG 297
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2462544982 240 YNPHCIFLFFLKNIGFDSTVLLDFLISSETCFLEYFVRYLKLLQKDWDNFFTIC 293
Cdd:pfam14694 298 CNPHCIFLFFLKNVAFDSTVLLDFLISSETCFLEYFVRYLKLLRENWDEFVSIC 351
LINES_C pfam14695
Lines C-terminus; This family represents the C-terminus of protein lines. In Drosophila this ...
463-498 1.05e-12

Lines C-terminus; This family represents the C-terminus of protein lines. In Drosophila this protein is involved in embryonic segmentation and may function as a transcriptional regulator.


:

Pssm-ID: 464267  Cd Length: 37  Bit Score: 62.22  E-value: 1.05e-12
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462544982 463 IVKCFQELQDAICRLQKKNLFPYNPTALLKLLKYIE 498
Cdd:pfam14695   1 AMSCLIRLRLAIDRLHRKNLFPYNPSPLLKLLEQCE 36
 
Name Accession Description Interval E-value
LINES_N pfam14694
Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this ...
1-293 0e+00

Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this protein is involved in embryonic segmentation and may function as a transcriptional regulator.


Pssm-ID: 464266  Cd Length: 351  Bit Score: 524.57  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544982   1 MCFLDLLELLIASRIHLKLHFTCQRILFLKPSCMLEVITWPIQAFVKRKVIIFLKKCLLCKVGEDLCRGSVPALMPPDHH 80
Cdd:pfam14694  58 ISFLDLLELLIASRINLSLHFICQRPLFLKLSCFLDLLNSPVPYFVKKKLILLLKKCLLYKSGEDLCRGSVPATLALDDM 137
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544982  81 VAVDMLALANAVLQAVNSGLLKTLSVYEKHSFFGGDEVQPECELITSPDHVILRAASLVIMKSLEIKFQNYSSASEMKVD 160
Cdd:pfam14694 138 LDEDMLALAHAVLQAVDLGLLDSLPVRGKPSRFGGSEVQPGCGGRGGPDHVLLRAASLLVLKSLEIKVQETRSASEIKRS 217
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544982 161 LQRFMSELLTFLKPHLQPSLQ-LHNPCKWLSRVFIEQDDDMLEAAKASLGIYLTLTRGCEATESLTQGKEMWDHHTHENG 239
Cdd:pfam14694 218 LQRVMSELLTFLKQHLPPQFHpETHPCEWLSRVFIEQDDDMLEAAKALLDIYLGLTRRHEATPSLSQEKESWNHHTHENG 297
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2462544982 240 YNPHCIFLFFLKNIGFDSTVLLDFLISSETCFLEYFVRYLKLLQKDWDNFFTIC 293
Cdd:pfam14694 298 CNPHCIFLFFLKNVAFDSTVLLDFLISSETCFLEYFVRYLKLLRENWDEFVSIC 351
LINES_C pfam14695
Lines C-terminus; This family represents the C-terminus of protein lines. In Drosophila this ...
463-498 1.05e-12

Lines C-terminus; This family represents the C-terminus of protein lines. In Drosophila this protein is involved in embryonic segmentation and may function as a transcriptional regulator.


Pssm-ID: 464267  Cd Length: 37  Bit Score: 62.22  E-value: 1.05e-12
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462544982 463 IVKCFQELQDAICRLQKKNLFPYNPTALLKLLKYIE 498
Cdd:pfam14695   1 AMSCLIRLRLAIDRLHRKNLFPYNPSPLLKLLEQCE 36
 
Name Accession Description Interval E-value
LINES_N pfam14694
Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this ...
1-293 0e+00

Lines N-terminus; This family represents the N-terminus of protein lines. In Drosophila this protein is involved in embryonic segmentation and may function as a transcriptional regulator.


Pssm-ID: 464266  Cd Length: 351  Bit Score: 524.57  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544982   1 MCFLDLLELLIASRIHLKLHFTCQRILFLKPSCMLEVITWPIQAFVKRKVIIFLKKCLLCKVGEDLCRGSVPALMPPDHH 80
Cdd:pfam14694  58 ISFLDLLELLIASRINLSLHFICQRPLFLKLSCFLDLLNSPVPYFVKKKLILLLKKCLLYKSGEDLCRGSVPATLALDDM 137
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544982  81 VAVDMLALANAVLQAVNSGLLKTLSVYEKHSFFGGDEVQPECELITSPDHVILRAASLVIMKSLEIKFQNYSSASEMKVD 160
Cdd:pfam14694 138 LDEDMLALAHAVLQAVDLGLLDSLPVRGKPSRFGGSEVQPGCGGRGGPDHVLLRAASLLVLKSLEIKVQETRSASEIKRS 217
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544982 161 LQRFMSELLTFLKPHLQPSLQ-LHNPCKWLSRVFIEQDDDMLEAAKASLGIYLTLTRGCEATESLTQGKEMWDHHTHENG 239
Cdd:pfam14694 218 LQRVMSELLTFLKQHLPPQFHpETHPCEWLSRVFIEQDDDMLEAAKALLDIYLGLTRRHEATPSLSQEKESWNHHTHENG 297
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2462544982 240 YNPHCIFLFFLKNIGFDSTVLLDFLISSETCFLEYFVRYLKLLQKDWDNFFTIC 293
Cdd:pfam14694 298 CNPHCIFLFFLKNVAFDSTVLLDFLISSETCFLEYFVRYLKLLRENWDEFVSIC 351
LINES_C pfam14695
Lines C-terminus; This family represents the C-terminus of protein lines. In Drosophila this ...
463-498 1.05e-12

Lines C-terminus; This family represents the C-terminus of protein lines. In Drosophila this protein is involved in embryonic segmentation and may function as a transcriptional regulator.


Pssm-ID: 464267  Cd Length: 37  Bit Score: 62.22  E-value: 1.05e-12
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462544982 463 IVKCFQELQDAICRLQKKNLFPYNPTALLKLLKYIE 498
Cdd:pfam14695   1 AMSCLIRLRLAIDRLHRKNLFPYNPSPLLKLLEQCE 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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