NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2462545239|ref|XP_054234464|]
View 

protein FAM219B isoform X2 [Homo sapiens]

Protein Classification

FAM219A domain-containing protein( domain architecture ID 10633719)

FAM219A domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FAM219A super family cl21117
Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This ...
 72-197 6.55e-60

Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This protein family has been found in eukaryotes. Proteins in this family are typically between 144 and 191 amino acids in length. There are two conserved sequence motifs: QLL and LDE.


The actual alignment was detected with superfamily member pfam15260:

Pssm-ID: 464600  Cd Length: 124  Bit Score: 183.10  E-value: 6.55e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462545239  72 QKHRDLAKAVLRRKGML-GASPNRPDSSGKRSVKFNKGYTALSQSPDENLVSLDSDSDGELGSRYSSGYSSAEVNQDVSR 150
Cdd:pfam15260   1 QKHRELAKAALRKKGLLgGAVLQQPRSGAKRSVKFNKGYTALSQSPEENLVSLDSDSDGELESRYSSGYSSAEVNQDLSR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2462545239 151 QLLQDGYHLDEIPDDEDLDLIPPKPMAsstCSCCWCCLGDSSSCTLQ 197
Cdd:pfam15260  81 QLLQDGYHLDEIPDDEDLDLIPPKPMG---SSTCACCLGESSSCTIQ 124
 
Name Accession Description Interval E-value
FAM219A pfam15260
Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This ...
 72-197 6.55e-60

Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This protein family has been found in eukaryotes. Proteins in this family are typically between 144 and 191 amino acids in length. There are two conserved sequence motifs: QLL and LDE.


Pssm-ID: 464600  Cd Length: 124  Bit Score: 183.10  E-value: 6.55e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462545239  72 QKHRDLAKAVLRRKGML-GASPNRPDSSGKRSVKFNKGYTALSQSPDENLVSLDSDSDGELGSRYSSGYSSAEVNQDVSR 150
Cdd:pfam15260   1 QKHRELAKAALRKKGLLgGAVLQQPRSGAKRSVKFNKGYTALSQSPEENLVSLDSDSDGELESRYSSGYSSAEVNQDLSR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2462545239 151 QLLQDGYHLDEIPDDEDLDLIPPKPMAsstCSCCWCCLGDSSSCTLQ 197
Cdd:pfam15260  81 QLLQDGYHLDEIPDDEDLDLIPPKPMG---SSTCACCLGESSSCTIQ 124
 
Name Accession Description Interval E-value
FAM219A pfam15260
Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This ...
 72-197 6.55e-60

Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This protein family has been found in eukaryotes. Proteins in this family are typically between 144 and 191 amino acids in length. There are two conserved sequence motifs: QLL and LDE.


Pssm-ID: 464600  Cd Length: 124  Bit Score: 183.10  E-value: 6.55e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462545239  72 QKHRDLAKAVLRRKGML-GASPNRPDSSGKRSVKFNKGYTALSQSPDENLVSLDSDSDGELGSRYSSGYSSAEVNQDVSR 150
Cdd:pfam15260   1 QKHRELAKAALRKKGLLgGAVLQQPRSGAKRSVKFNKGYTALSQSPEENLVSLDSDSDGELESRYSSGYSSAEVNQDLSR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2462545239 151 QLLQDGYHLDEIPDDEDLDLIPPKPMAsstCSCCWCCLGDSSSCTLQ 197
Cdd:pfam15260  81 QLLQDGYHLDEIPDDEDLDLIPPKPMG---SSTCACCLGESSSCTIQ 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH