NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2466818105|ref|XP_054502455|]
View 

adenylate kinase isoenzyme 1 isoform X2 [Agelaius phoeniceus]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11492279)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 51-238 6.29e-139

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


:

Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 387.25  E-value: 6.29e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  51 KQHKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVAKAD 130
Cdd:TIGR01360   1 AKCKIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 131 VSKGFLIDGYPREVKQGEEFEKKIAPPTLLLYVDAGKDTMVKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYK 210
Cdd:TIGR01360  81 TSKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYE 160

                         170       180
                  ....*....|....*....|....*...
gi 2466818105 211 SRGIVRQLNAEGSVEEVFQQVCTHLDCL 238
Cdd:TIGR01360 161 TKGKLRKINAEGTVDDVFLQVCTAIDKL 188
 
Name Accession Description Interval E-value
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 51-238 6.29e-139

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 387.25  E-value: 6.29e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  51 KQHKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVAKAD 130
Cdd:TIGR01360   1 AKCKIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 131 VSKGFLIDGYPREVKQGEEFEKKIAPPTLLLYVDAGKDTMVKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYK 210
Cdd:TIGR01360  81 TSKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYE 160

                         170       180
                  ....*....|....*....|....*...
gi 2466818105 211 SRGIVRQLNAEGSVEEVFQQVCTHLDCL 238
Cdd:TIGR01360 161 TKGKLRKINAEGTVDDVFLQVCTAIDKL 188
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 55-227 4.08e-80

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 238.68  E-value: 4.08e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  55 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSKG 134
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERL-KKPDCKKG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 135 FLIDGYPREVKQGEEFEKKI---APPTLLLYVDAGKDTMVKRLLKRGET-------------------SGRVDDNEETIK 192
Cdd:cd01428    80 FILDGFPRTVDQAEALDELLdegIKPDKVIELDVPDEVLIERILGRRICpvsgrvyhlgkddvtgeplSQRSDDNEETIK 159

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2466818105 193 KRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEEV 227
Cdd:cd01428   160 KRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
58-212 8.95e-75

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 224.50  E-value: 8.95e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  58 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSKGFLI 137
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERL-EQNDCKNGFLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 138 DGYPREVKQGEEFE---KKIAPPTLLLYVDAGKDTMVKRLLKRGET---------------------------SGRVDDN 187
Cdd:pfam00406  80 DGFPRTVPQAEALEellERGIKLDYVIEFDVPDEVLVERLTGRRIHpnsgrsyhlefnppkvpgkddvtgeplVQRSDDN 159

                         170       180
                  ....*....|....*....|....*
gi 2466818105 188 EETIKKRLETYYKATEPVIAFYKSR 212
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 54-235 3.02e-72

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 219.23  E-value: 3.02e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSK 133
Cdd:COG0563     2 RIILL-GPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERL-AQPDCAN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFLIDGYPREVKQGEEFEKKIA----PPTLLLYVDAGKDTMVKRLLKR---------------------------GETSG 182
Cdd:COG0563    80 GFILDGFPRTVAQAEALDELLAelgiKLDAVIELDVDDEELVERLSGRrvcpncgatyhvkfnppkvegvcdkcgGELVQ 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2466818105 183 RVDDNEETIKKRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEEVFQQVCTHL 235
Cdd:COG0563   160 RADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk PRK00279
adenylate kinase; Reviewed
 54-236 1.69e-69

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 212.32  E-value: 1.69e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSK 133
Cdd:PRK00279    2 RLILL-GPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERL-AQPDCKN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFLIDGYPREVKQGEEFEKKIA----PPTLLLYVDAGKDTMVKRLLKR---------------------------GETSG 182
Cdd:PRK00279   80 GFLLDGFPRTIPQAEALDEMLKelgiKLDAVIEIDVPDEELVERLSGRricpacgrtyhvkfnppkvegkcdvcgEELIQ 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2466818105 183 RVDDNEETIKKRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEEVFQQVCTHLD 236
Cdd:PRK00279  160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALG 213
 
Name Accession Description Interval E-value
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 51-238 6.29e-139

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 387.25  E-value: 6.29e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  51 KQHKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVAKAD 130
Cdd:TIGR01360   1 AKCKIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 131 VSKGFLIDGYPREVKQGEEFEKKIAPPTLLLYVDAGKDTMVKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYK 210
Cdd:TIGR01360  81 TSKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYE 160

                         170       180
                  ....*....|....*....|....*...
gi 2466818105 211 SRGIVRQLNAEGSVEEVFQQVCTHLDCL 238
Cdd:TIGR01360 161 TKGKLRKINAEGTVDDVFLQVCTAIDKL 188
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 55-227 4.08e-80

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 238.68  E-value: 4.08e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  55 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSKG 134
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERL-KKPDCKKG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 135 FLIDGYPREVKQGEEFEKKI---APPTLLLYVDAGKDTMVKRLLKRGET-------------------SGRVDDNEETIK 192
Cdd:cd01428    80 FILDGFPRTVDQAEALDELLdegIKPDKVIELDVPDEVLIERILGRRICpvsgrvyhlgkddvtgeplSQRSDDNEETIK 159

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2466818105 193 KRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEEV 227
Cdd:cd01428   160 KRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
58-212 8.95e-75

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 224.50  E-value: 8.95e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  58 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSKGFLI 137
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERL-EQNDCKNGFLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 138 DGYPREVKQGEEFE---KKIAPPTLLLYVDAGKDTMVKRLLKRGET---------------------------SGRVDDN 187
Cdd:pfam00406  80 DGFPRTVPQAEALEellERGIKLDYVIEFDVPDEVLVERLTGRRIHpnsgrsyhlefnppkvpgkddvtgeplVQRSDDN 159

                         170       180
                  ....*....|....*....|....*
gi 2466818105 188 EETIKKRLETYYKATEPVIAFYKSR 212
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 54-235 3.02e-72

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 219.23  E-value: 3.02e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSK 133
Cdd:COG0563     2 RIILL-GPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERL-AQPDCAN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFLIDGYPREVKQGEEFEKKIA----PPTLLLYVDAGKDTMVKRLLKR---------------------------GETSG 182
Cdd:COG0563    80 GFILDGFPRTVAQAEALDELLAelgiKLDAVIELDVDDEELVERLSGRrvcpncgatyhvkfnppkvegvcdkcgGELVQ 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2466818105 183 RVDDNEETIKKRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEEVFQQVCTHL 235
Cdd:COG0563   160 RADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 55-231 1.00e-70

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 214.54  E-value: 1.00e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  55 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVS-SGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVAKADvSK 133
Cdd:TIGR01359   1 VVFVLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKrEGSENGSLIESYIKEGKIVPSEVTVELLKKAIQEDGS-SK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFLIDGYPREVKQGEEFEKKI---APPTLLLYVDAGKDTMVKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYK 210
Cdd:TIGR01359  80 KFLIDGFPRNEENLEAWEKLMdnkVNFKFVLFFDCPEETMIKRLLKRGQTSGRVDDNIETLKKRFRTYNEETLPIIEHFE 159

                         170       180
                  ....*....|....*....|.
gi 2466818105 211 SRGIVRQLNAEGSVEEVFQQV 231
Cdd:TIGR01359 160 NKGKVKEINAEGSVEEVFEDV 180
adk PRK00279
adenylate kinase; Reviewed
 54-236 1.69e-69

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 212.32  E-value: 1.69e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSK 133
Cdd:PRK00279    2 RLILL-GPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERL-AQPDCKN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFLIDGYPREVKQGEEFEKKIA----PPTLLLYVDAGKDTMVKRLLKR---------------------------GETSG 182
Cdd:PRK00279   80 GFLLDGFPRTIPQAEALDEMLKelgiKLDAVIEIDVPDEELVERLSGRricpacgrtyhvkfnppkvegkcdvcgEELIQ 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2466818105 183 RVDDNEETIKKRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEEVFQQVCTHLD 236
Cdd:PRK00279  160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALG 213
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 54-231 2.72e-61

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 191.29  E-value: 2.72e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVAKADVSK 133
Cdd:TIGR01351   1 RLVLL-GPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDNEN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFLIDGYPREVKQGEEFEKKIA-PPTLLLYVDAGKDTMVKRLLKRG--ETSGRV-------------------------D 185
Cdd:TIGR01351  80 GFILDGFPRTLSQAEALDALLEePIDAVIELDVPDEELVERLSGRRicPSCGRVyhlkfnppkvpgcddctgellvqreD 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2466818105 186 DNEETIKKRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEEVFQQV 231
Cdd:TIGR01351 160 DTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRI 205
PLN02200 PLN02200
adenylate kinase family protein
 47-231 7.19e-54

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 173.15  E-value: 7.19e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  47 PEKLKQHKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMv 126
Cdd:PLN02200   37 SSKEKTPFITFVLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEM- 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 127 AKADVSKgFLIDGYPREVKQGEEFEKKI-APPTLLLYVDAGKDTMVKRLLKRGEtsGRVDDNEETIKKRLETYYKATEPV 205
Cdd:PLN02200  116 ESSDNNK-FLIDGFPRTEENRIAFERIIgAEPNVVLFFDCPEEEMVKRVLNRNQ--GRVDDNIDTIKKRLKVFNALNLPV 192

                         170       180
                  ....*....|....*....|....*.
gi 2466818105 206 IAFYKSRGIVRQLNAEGSVEEVFQQV 231
Cdd:PLN02200  193 IDYYSKKGKLYTINAVGTVDEIFEQV 218
PRK14531 PRK14531
adenylate kinase; Provisional
 52-236 2.44e-51

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 164.98  E-value: 2.44e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  52 QHKIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvaKADV 131
Cdd:PRK14531    2 KQRLLFL-GPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQL--KALN 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 132 SKGFLIDGYPREVKQGEEFE------KKIAPPTLLLYVDagKDTMVKRLLKRgetsGRVDDNEETIKKRLETYYKATEPV 205
Cdd:PRK14531   79 SGGWLLDGFPRTVAQAEALEplleelKQPIEAVVLLELD--DAVLIERLLAR----GRADDNEAVIRNRLEVYREKTAPL 152

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2466818105 206 IAFYKSRGIVRQLNAEGSVEEVFQQVCTHLD 236
Cdd:PRK14531  153 IDHYRQRGLLQSVEAQGSIEAITERIEKVLA 183
PRK14527 PRK14527
adenylate kinase; Provisional
 54-231 5.94e-51

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 164.19  E-value: 5.94e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVAKADVSK 133
Cdd:PRK14527    7 KVVIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPVRV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFliDGYPREVKQGEEFEKKI----APPTLLLYVDAGKDTMVKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFY 209
Cdd:PRK14527   87 IF--DGFPRTLAQAEALDRLLeelgARLLAVVLLEVPDEELIRRIVERARQEGRSDDNEETVRRRQQVYREQTQPLVDYY 164

                         170       180
                  ....*....|....*....|..
gi 2466818105 210 KSRGIVRQLNAEGSVEEVFQQV 231
Cdd:PRK14527  165 EARGHLKRVDGLGTPDEVYARI 186
PRK14528 PRK14528
adenylate kinase; Provisional
 54-227 2.48e-47

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 154.78  E-value: 2.48e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVaKADVSK 133
Cdd:PRK14528    3 NIIFM-GPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIR-EADCKN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFLIDGYPREVKQGEEFEKKIAPPTL----LLYVDAGKDTMVKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFY 209
Cdd:PRK14528   81 GFLLDGFPRTVEQADALDALLKNEGKsidkAINLEVPDGELLKRLLGRAEIEGRADDNEATIKNRLDNYNKKTLPLLDFY 160

                         170
                  ....*....|....*...
gi 2466818105 210 KSRGIVRQLNAEGSVEEV 227
Cdd:PRK14528  161 AAQKKLSQVNGVGSLEEV 178
PRK14532 PRK14532
adenylate kinase; Provisional
 55-227 3.36e-46

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 151.90  E-value: 3.36e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  55 IIFvvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSKG 134
Cdd:PRK14532    4 ILF--GPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERL-PEAEAAGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 135 FLIDGYPREVKQGEEFEKKIAP------PTLLLYVDagKDTMVKRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAF 208
Cdd:PRK14532   81 AIFDGFPRTVAQAEALDKMLASrgqkidVVIRLKVD--DEALIERIVKRFEEQGRPDDNPEVFVTRLDAYNAQTAPLLPY 158

                         170
                  ....*....|....*....
gi 2466818105 209 YKSRGIVRQLNAEGSVEEV 227
Cdd:PRK14532  159 YAGQGKLTEVDGMGSIEAV 177
AAA_17 pfam13207
AAA domain;
59-192 9.05e-46

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 148.93  E-value: 9.05e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  59 VGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSerGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSKGFLID 138
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERI-AEEAGEGGVIVD 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 139 GYPREVKQGEEFEK------KIAPPTLLLYVDAGKDTMVKRLLKRgETSGRVDDNEETIK 192
Cdd:pfam13207  78 GHPRIKTPAGYLPGlpvevlRELKPDAIILLEADPEEILERRLKD-RTRGRDDDSEEEIR 136
adk PRK02496
adenylate kinase; Provisional
 54-227 3.79e-44

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 146.43  E-value: 3.79e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKADVSK 133
Cdd:PRK02496    3 RLIFL-GPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERL-QQPDAAN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFLIDGYPREVKQGEEFEK---KIAPPT-LLLYVDAGKDTMVKRLLKRgetsGRVDDNEETIKKRLETYYKATEPVIAFY 209
Cdd:PRK02496   81 GWILDGFPRKVTQAAFLDEllqEIGQSGeRVVNLDVPDDVVVERLLAR----GRKDDTEEVIRRRLEVYREQTAPLIDYY 156

                         170
                  ....*....|....*...
gi 2466818105 210 KSRGIVRQLNAEGSVEEV 227
Cdd:PRK02496  157 RDRQKLLTIDGNQSVEAV 174
PLN02842 PLN02842
nucleotide kinase
 58-236 1.32e-38

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 140.00  E-value: 1.32e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  58 VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVAKADVSKGFLI 137
Cdd:PLN02842    2 ISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDAKEKGWLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 138 DGYPREVKQGEEFEKKIAPPTLLLYVDAGKDTMVKRLLKR-------------------GETSGRV----DDNEETIKKR 194
Cdd:PLN02842   82 DGYPRSFAQAQSLEKLKIRPDIFILLDVPDEILIDRCVGRrldpvtgkiyhiknfppesEEIKARLitrpDDTEEKVKAR 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2466818105 195 LETYYKATEPVIAFYKSrgIVRQLNAEGSVEEVFQQVCTHLD 236
Cdd:PLN02842  162 LQIYKKNAEAILSTYSD--IMVKIDGNRPKEVVFEEISSLLS 201
PRK14530 PRK14530
adenylate kinase; Provisional
 53-236 2.05e-37

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 130.29  E-value: 2.05e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  53 HKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRA---------EVSSGSERgkklqAIMEKGELVPlDTVLDMLRD 123
Cdd:PRK14530    3 QPRILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRAnkqmdisdmDTEYDTPG-----EYMDAGELVP-DAVVNEIVE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 124 AMVAKADvskGFLIDGYPREVKQGEEFEKkIAPPTLLLYVDAGKDTMVKRLLKR-------------------------- 177
Cdd:PRK14530   77 EALSDAD---GFVLDGYPRNLEQAEYLES-ITDLDVVLYLDVSEEELVDRLTGRrvcpdcganyhvefnqpeeegvcdec 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 178 -GETSGRVDDNEETIKKRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEEVFQQVCTHLD 236
Cdd:PRK14530  153 gGELIQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQDAID 212
PLN02674 PLN02674
adenylate kinase
 51-231 4.93e-34

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 122.30  E-value: 4.93e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  51 KQHKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvAKAD 130
Cdd:PLN02674   29 KPDKRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAM-KKPS 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 131 VSKGFLIDGYPREV-----------KQGEEFEK------------------------------KIAPPTLllyvdAGKDT 169
Cdd:PLN02674  108 CQKGFILDGFPRTVvqaqkldemlaKQGAKIDKvlnfaiddaileeritgrwihpssgrtyhtKFAPPKV-----PGVDD 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2466818105 170 MVKRLLKRgetsgRVDDNEETIKKRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEEVFQQV 231
Cdd:PLN02674  183 VTGEPLIQ-----RKDDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAEKPPKEVTAEV 239
PRK13808 PRK13808
adenylate kinase; Provisional
 56-231 2.07e-31

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 117.68  E-value: 2.07e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  56 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDaMVAKADVSKGF 135
Cdd:PRK13808    3 LILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISD-RIEQPDAANGF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 136 LIDGYPREVKQGEEF-----EKKIAPPTLL-LYVDAGK-----DTMVKRLLKRGETSgRVDDNEETIKKRLETYYKATEP 204
Cdd:PRK13808   82 ILDGFPRTVPQAEALdallkDKQLKLDAVVeLRVNEGAllarvETRVAEMRARGEEV-RADDTPEVLAKRLASYRAQTEP 160

                         170       180
                  ....*....|....*....|....*..
gi 2466818105 205 VIAFYKSRGIVRQLNAEGSVEEVFQQV 231
Cdd:PRK13808  161 LVHYYSEKRKLLTVDGMMTIDEVTREI 187
PLN02459 PLN02459
probable adenylate kinase
 60-226 2.32e-29

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 110.71  E-value: 2.32e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  60 GGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVA-KADVSKGFLID 138
Cdd:PLN02459   36 GCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEAgEEEGESGFILD 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 139 GYPREVKQGEEFEkKIAPPTLLLYVDAGKDTMVKRLLKR---GETSG--------------------------------- 182
Cdd:PLN02459  116 GFPRTVRQAEILE-GVTDIDLVVNLKLREEVLVEKCLGRricSECGKnfnvadidlkgedgrpgivmppllpppecaskl 194

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2466818105 183 --RVDDNEETIKKRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEE 226
Cdd:PLN02459  195 itRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEFELPGGIPE 240
PRK14526 PRK14526
adenylate kinase; Provisional
 54-227 2.37e-26

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 101.47  E-value: 2.37e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVvGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVAKADvSK 133
Cdd:PRK14526    2 KLVFL-GPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKN-ND 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFLIDGYPREVKQGEEFEkKIAPPTLLLYVDAGKDTMVKRLLKR---------------------------GETSGRVDD 186
Cdd:PRK14526   80 NFILDGFPRNINQAKALD-KFLPNIKIINFLIDEELLIKRLSGRrickscnnifniytlptkekgicdvckGDLYQRKDD 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2466818105 187 NEETIKKRLETYYKATEPVIAFYKSRGIVRQLNAEGSVEEV 227
Cdd:PRK14526  159 KEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKDIDEV 199
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 49-214 8.62e-26

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 100.26  E-value: 8.62e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  49 KLKQHKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVAK 128
Cdd:PTZ00088    2 KLKGPLKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 129 AD-VSKGFLIDGYPREVKQGEEFeKKIAPPTLLLYVDAGKDTMVKRLLKR----------------------------GE 179
Cdd:PTZ00088   82 TDdCFKGFILDGFPRNLKQCKEL-GKITNIDLFVNIYLPRNILIKKLLGRricntcnrnfniahirsdpydmppilppAD 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2466818105 180 TSG---------RVDDNEETIKKRLETYYKATEPVIAFYKSRGI 214
Cdd:PTZ00088  161 CEGckgnpklqkRSDDTEEIVAHRLNTYESTNSPIIQFFKNENC 204
PRK14529 PRK14529
adenylate kinase; Provisional
 56-227 8.97e-23

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 92.47  E-value: 8.97e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  56 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMvaKADVSKGF 135
Cdd:PRK14529    3 ILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETL--KQDGKNGW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 136 LIDGYPREVKQGEEFEKKIAPPTLLL-YV-------DAGKD-TMVKRLLKR------------------------GETSG 182
Cdd:PRK14529   81 LLDGFPRNKVQAEKLWEALQKEGMKLdYVieillprEVAKNrIMGRRLCKNdnnhpnnifidaikpdgdvcrvcgGELST 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2466818105 183 RVDD-NEETIKKRLETYYKATEPVIA---FYK---SRGIVR--QLNAEGSVEEV 227
Cdd:PRK14529  161 RADDqDEEAINKRHDIYYDTETGTLAaayFFKdlaAKGSTKyiELDGEGSIDEI 214
TMPK cd01672
Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the ...
 54-236 4.59e-09

Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step in either de novo or salvage biosynthesis of thymidine triphosphate (TTP).


Pssm-ID: 238835  Cd Length: 200  Bit Score: 54.58  E-value: 4.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVVGGPGSGKGTQCEKIVQ---KYGYTHLSTGDLlraevsSGSERGKKLQAIMEKGELVPLDTVLDML-----RDAM 125
Cdd:cd01672     1 MFIVFEGIDGAGKTTLIELLAErleARGYEVVLTREP------GGTPIGEAIRELLLDPEDEKMDPRAELLlfaadRAQH 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 126 VA---KADVSKGFLI--D----------GYPR-----EVKQGEEFEKKIAPPTLLLYVDAGKDTMVKRLLKRGETSGRVD 185
Cdd:cd01672    75 VEeviKPALARGKIVlsDrfvdsslayqGAGRglgeaLIEALNDLATGGLKPDLTILLDIDPEVGLARIEARGRDDRDEQ 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2466818105 186 DNEETIKKRLETYYKatepVIAFYKSRGIVrqLNAEGSVEEVFQQVCTHLD 236
Cdd:cd01672   155 EGLEFHERVREGYLE----LAAQEPERIIV--IDASQPLEEVLAEILKAIL 199
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 56-198 4.98e-07

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 47.69  E-value: 4.98e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  56 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAImekGELVPlDTVLDMLRDAMVAKADVskgf 135
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEELGAVRLSSDDERKRLFGEGRPSISYYTDA---TDRTY-ERLHELARIALRAGRPV---- 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2466818105 136 LIDG---YPREVKQGEEFEKKIAPPTLLLYVDAGKDTMVKRLLKRGETSG-RVDDNEETIKKRLETY 198
Cdd:pfam13671  74 ILDAtnlRRDERARLLALAREYGVPVRIVVFEAPEEVLRERLAARARAGGdPSDVPEEVLDRQKARF 140
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
55-227 7.02e-07

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 47.60  E-value: 7.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  55 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTgDLLRAEVssgseRGKKLQAIMEKGELVPL--DTVLDMLRDAMVAKADVs 132
Cdd:COG0645     1 LILVCGLPGSGKSTLARALAERLGAVRLRS-DVVRKRL-----FGAGLAPLERSPEATARtyARLLALARELLAAGRSV- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 133 kgfLIDG---YPREVKQGEEFEKKIAPPTLLLYVDAGKDTMVKRLLKRGETSGRVDDNEETIKKRLETYykatEPVIAFY 209
Cdd:COG0645    74 ---ILDAtflRRAQREAFRALAEEAGAPFVLIWLDAPEEVLRERLEARNAEGGDSDATWEVLERQLAFE----EPLTEDE 146

                         170
                  ....*....|....*...
gi 2466818105 210 KSRGIVRQLNAEGSVEEV 227
Cdd:COG0645   147 GFLLVVDTSGLEEALAAL 164
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
54-194 9.29e-07

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 47.63  E-value: 9.29e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVVGGPGSGKGtQCEKIVQKYGYTHLSTGDLLRAEVssgSERGkklqaimekgeLVPLDTVLDM----LR-----DA 124
Cdd:PRK01184    2 KIIGVVGMPGSGKG-EFSKIAREMGIPVVVMGDVIREEV---KKRG-----------LEPTDENIGKvaidLRkelgmDA 66

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2466818105 125 mVAKADVSK-------GFLIDGYpREVKQGEEFEKKIAPPTLLLYVDAGKDTMVKRLLKRgetsGRVDDNE--ETIKKR 194
Cdd:PRK01184   67 -VAKRTVPKirekgdeVVVIDGV-RGDAEVEYFRKEFPEDFILIAIHAPPEVRFERLKKR----GRSDDPKswEELEER 139
PRK04182 PRK04182
cytidylate kinase; Provisional
 55-194 1.13e-06

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 47.49  E-value: 1.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  55 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLR--AEvssgsERGKKLQAIMEKGELVP-LDTVLD-MLRDAMVAKAD 130
Cdd:PRK04182    2 IITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRelAK-----ERGMSLEEFNKYAEEDPeIDKEIDrRQLEIAEKEDN 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2466818105 131 V---SK--GFLIDGYprevkqgeefekkiapPTLLLYVDAGKDTMVKRLLKRGETSgrVDDNEETIKKR 194
Cdd:PRK04182   77 VvleGRlaGWMAKDY----------------ADLKIWLKAPLEVRAERIAEREGIS--VEEALEETIER 127
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 55-98 1.78e-05

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 43.24  E-value: 1.78e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2466818105  55 IIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSER 98
Cdd:cd02020     1 IIAIDGPAGSGKSTVAKLLAKKLGLPYLDTGGIRTEEVGKLASE 44
Thymidylate_kin pfam02223
Thymidylate kinase;
60-231 2.95e-04

Thymidylate kinase;


Pssm-ID: 396690  Cd Length: 184  Bit Score: 40.36  E-value: 2.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  60 GGPGSGKGTQCEKIVQKYGYTHLSTgdLLRAEvSSGSERGKKL-QAIMEKGELVPLDTVLDMLRD-----AMVAKADVSK 133
Cdd:pfam02223   3 GLDGAGKTTQAELLKERLKEQGIKV--VFTRE-PGGTPIGEKIrELLLRNEELSPLTEALLFAADriqhlEQKIKPALKQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105 134 GFLIDG---------YPREVKQGEEFEKKIAP-----PTLLLYVDAGKDTMVKRLLKRGEtsgrvddNEETIKKRLETYY 199
Cdd:pfam02223  80 GKTVIVdrylfsgiaYQGAKGGDLDLVLSLNPdvpgkPDLTFLLDVDPEVALKRLRRRGE-------LEKTEFEQLDFLR 152

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2466818105 200 KATEPVIAFYKSRGIVRQLNAEGSVEEVFQQV 231
Cdd:pfam02223 153 KVRERYLELAKFDERIKIIDASLSIEEVHEEI 184
AAA_18 pfam13238
AAA domain;
56-189 3.79e-04

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 39.33  E-value: 3.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  56 IFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLQAIMEKGELVPLDTVLDMLRDAMVAKADVSKGF 135
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSKRLGFGDNVRDLALENGLVLGDDPETRESKRLDEDKLDRLLDLLEENAALEEGGNLIIDGH 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2466818105 136 LIDGYPREVKQGEEFekkiapptlllYVDAGKDTMVKRLLKRGETSGRVDDNEE 189
Cdd:pfam13238  81 LAELEPERAKDLVGI-----------VLRASPEELLERLEKRGYEEAKIKENEE 123
Gmk COG0194
Guanylate kinase [Nucleotide transport and metabolism];
154-200 1.71e-03

Guanylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 439964  Cd Length: 190  Bit Score: 38.13  E-value: 1.71e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2466818105 154 IAPPTLllyvdagkDTMVKRLLKRGetsgrvDDNEETIKKRLETYYK 200
Cdd:COG0194   119 ILPPSL--------EELERRLRGRG------TDSEEVIERRLAKARE 151
pseT PHA02530
polynucleotide kinase; Provisional
 54-201 8.60e-03

polynucleotide kinase; Provisional


Pssm-ID: 222856 [Multi-domain]  Cd Length: 300  Bit Score: 36.54  E-value: 8.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2466818105  54 KIIFVVGGPGSGKGTQCEKIVQK-YGYTHLSTGDL---LRAEVSSGSERGKKlqaimEKGELVpldTVldMLRDAMVAKA 129
Cdd:PHA02530    3 KIILTVGVPGSGKSTWAREFAAKnPKAVNVNRDDLrqsLFGHGEWGEYKFTK-----EKEDLV---TK--AQEAAALAAL 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2466818105 130 DVSKGFLIDG---YPREVKQGEEFEKKIAPPTLLLYVDAGKDTMVKRLLKRGETSGRVDdneetIKKRLETYYKA 201
Cdd:PHA02530   73 KSGKSVIISDtnlNPERRRKWKELAKELGAEFEEKVFDVPVEELVKRNRKRGERAVPED-----VLRSMFKQMKE 142
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH