|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1375-2063 |
4.43e-29 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 128.72 E-value: 4.43e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1375 QEGEPVSIDEEATR-------------EEVTGQEEMPEAGKQRLEKEEGLQEAEEETQEKDKEKEVAFLESEDVVKGKRR 1441
Cdd:PTZ00121 1104 KKTETGKAEEARKAeeakkkaedarkaEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARK 1183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1442 P---------RKGRKTRKTVKQEKMEKDERIEETISAEE---LAVTLKPEEV---AEEGEGRSKKRKGTWEEEEGAEKRE 1506
Cdd:PTZ00121 1184 AeevrkaeelRKAEDARKAEAARKAEEERKAEEARKAEDakkAEAVKKAEEAkkdAEEAKKAEEERNNEEIRKFEEARMA 1263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1507 KEEEEEQMIEPKEAITEAVERKlswVEWKSHWDEWQKAQTQRAVlwEDWKKQCDKKHFEEEARLRVEGKLQPSEEV---- 1582
Cdd:PTZ00121 1264 HFARRQAAIKAEEARKADELKK---AEEKKKADEAKKAEEKKKA--DEAKKKAEEAKKADEAKKKAEEAKKKADAAkkka 1338
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1583 EEPKKMltwDEWREVWENilhtKSEKELDLGEMFKEGEEEEEEEEEEIGEEEEEEEeeiyeeeaegrKERRQIRMAQKQA 1662
Cdd:PTZ00121 1339 EEAKKA---AEAAKAEAE----AAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA-----------EEKKKADEAKKKA 1400
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1663 RADWRQARGERRRAREKK----LLAHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHIEMTLGEK----ETFLSQQ 1734
Cdd:PTZ00121 1401 EEDKKKADELKKAAAAKKkadeAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAkkadEAKKKAE 1480
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1735 EEILSREAEFLAQKKKKLARKLEKMAHEKEKiAKKINKVEEV-KAVLAQKTEtmmekEKNLASEEKKVREEAKNQELDGQ 1813
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAKKKADEAKKAAEAKKK-ADEAKKAEEAkKADEAKKAE-----EAKKADEAKKAEEKKKADELKKA 1554
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1814 ELALKEDEL--YEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREK 1891
Cdd:PTZ00121 1555 EELKKAEEKkkAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKK 1634
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1892 LREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKL-SLEKERLTERGKAlhDKEKKLLKGKEQLQDIKGKLE 1970
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAeEAKKAEEDEKKAA--EALKKEAEEAKKAEELKKKEA 1712
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1971 TYREKlinlSKKLMEEKTVFVAKKEKLtvteKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETE-IIKEA 2049
Cdd:PTZ00121 1713 EEKKK----AEELKKAEEENKIKAEEA----KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEaVIEEE 1784
|
730
....*....|....
gi 2482565915 2050 EELTSEMKRVAREK 2063
Cdd:PTZ00121 1785 LDEEDEKRRMEVDK 1798
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1384-2048 |
6.54e-24 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 111.77 E-value: 6.54e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1384 EEATREEVTGQEEMPEAGKQRLEKEEGLQEAEeetQEKDKEKEVAFLESEDVVKGKRRPR-KGRKTRKTVKQEKMEKDER 1462
Cdd:PTZ00121 1215 EEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE---EERNNEEIRKFEEARMAHFARRQAAiKAEEARKADELKKAEEKKK 1291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1463 IEETISAEELAvtlKPEEVAEEGEGRSK----KRKGTWEEEEGAEKREKEEEEEQMIEPKEAITEAVERKLSWVEWKSHW 1538
Cdd:PTZ00121 1292 ADEAKKAEEKK---KADEAKKKAEEAKKadeaKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEA 1368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1539 DEWQKAQTQRAVlwEDWKKQCDKKHFEEEARLRVEGKLQPSEEV----EEPKKMltwDEwrevweniLHTKSEKELDLGE 1614
Cdd:PTZ00121 1369 AEKKKEEAKKKA--DAAKKKAEEKKKADEAKKKAEEDKKKADELkkaaAAKKKA---DE--------AKKKAEEKKKADE 1435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1615 MFKEGEEEEEEEEEEIGEEEEEEEEEIYEEEAEGRKERRQIRMAQKQARADWRQARGERRRAREKKLLAHEEEKLAQEER 1694
Cdd:PTZ00121 1436 AKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA 1515
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1695 RLAqEEGKLAHEYVKS--ATKGGKLAHIEMTLGEKEtfLSQQEEILSREAEFLAQKKKKlARKLEKMAHEKEKIAKKINK 1772
Cdd:PTZ00121 1516 KKA-EEAKKADEAKKAeeAKKADEAKKAEEKKKADE--LKKAEELKKAEEKKKAEEAKK-AEEDKNMALRKAEEAKKAEE 1591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1773 VEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQEldgQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSL 1852
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA---EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK 1668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1853 EEEmlaqEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERH 1932
Cdd:PTZ00121 1669 KAE----EDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK 1744
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1933 KLSLEKERLTERGKALHdkekkllkgkEQLQDIKGKLETYREKLINLSKKLMEEKTVFVAKKEKlTVTEKKIEMEDMLLA 2012
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAH----------LKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK-KIKDIFDNFANIIEG 1813
|
650 660 670
....*....|....*....|....*....|....*...
gi 2482565915 2013 EKQGKLAVEKVK--LAKEITEVIQNSQLIREETEIIKE 2048
Cdd:PTZ00121 1814 GKEGNLVINDSKemEDSAIKEVADSKNMQLEEADAFEK 1851
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1378-2003 |
1.23e-22 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 107.53 E-value: 1.23e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1378 EPVSIDEEATR--EEVTGQEEMPEAGKQRLEKEEGLQEAEE-----------ETQEKDKEKEVAFLE----SEDVVKGKR 1440
Cdd:PTZ00121 1233 EEAKKDAEEAKkaEEERNNEEIRKFEEARMAHFARRQAAIKaeearkadelkKAEEKKKADEAKKAEekkkADEAKKKAE 1312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1441 RPRKGRKTRKTVKQEKMEKDE---RIEETISAEELAvTLKPEEVAEEGEGRSKKRKGTweeeeGAEKREKEEEEEQMIEP 1517
Cdd:PTZ00121 1313 EAKKADEAKKKAEEAKKKADAakkKAEEAKKAAEAA-KAEAEAAADEAEAAEEKAEAA-----EKKKEEAKKKADAAKKK 1386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1518 KEAITEAVERKLSWVEWKSHWDEWQKAQTQRAVLwEDWKKQCDKKHFEEEARLRVEGKLQPSE---EVEEPKKMltwdew 1594
Cdd:PTZ00121 1387 AEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA-DEAKKKAEEKKKADEAKKKAEEAKKADEakkKAEEAKKA------ 1459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1595 revwENiLHTKSEKELDLGEMFKEGEEEEEEEEEEIGEEEEEEEEEIYEEEAEGRKERRQIRMAQKQARADwrQARGERR 1674
Cdd:PTZ00121 1460 ----EE-AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAD--EAKKAEE 1532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1675 RAREKKLLAHEEEKLAQEERRlaQEEGKLAHEyVKSATKGGKLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKKLAR 1754
Cdd:PTZ00121 1533 AKKADEAKKAEEKKKADELKK--AEELKKAEE-KKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1755 KLEKMAHEKEKIAKKINKVEEVKavlaQKTETMMEKEknlaSEEKKVREEAKNQEldgQELALKEDELYEEAEKLEDKRE 1834
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEELKKAEEEK----KKVEQLKKKE----AEEKKKAEELKKAE---EENKIKAAEEAKKAEEDKKKAE 1678
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1835 ALAKEEEmlalyEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELK 1914
Cdd:PTZ00121 1679 EAKKAEE-----DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDE 1753
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1915 VKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDkEKKLLKGKEQLQDIKGKLETYREK------LINLSKKLMEEKT 1988
Cdd:PTZ00121 1754 EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEED-EKRRMEVDKKIKDIFDNFANIIEGgkegnlVINDSKEMEDSAI 1832
|
650
....*....|....*
gi 2482565915 1989 VFVAKKEKLTVTEKK 2003
Cdd:PTZ00121 1833 KEVADSKNMQLEEAD 1847
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1684-2254 |
1.20e-21 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 103.61 E-value: 1.20e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1684 HEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKKLaRKLEKMAHEK 1763
Cdd:PRK03918 207 REINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEI-EELEEKVKEL 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1764 EKIAKKINKVEEVKAVLAQKTETMMEKEKNLAseekKVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEEEML 1843
Cdd:PRK03918 286 KELKEKAEEYIKLSEFYEEYLDELREIEKRLS----RLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERH 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1844 ALYEKNLSLEEEMlaqeakhqmeeEKrlaLEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQM 1923
Cdd:PRK03918 362 ELYEEAKAKKEEL-----------ER---LKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKA 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1924 EESLSQERHKLSLEKERLTE--RGKALHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLMEEKTVFVAKK--EKLTV 1999
Cdd:PRK03918 428 IEELKKAKGKCPVCGRELTEehRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKE 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2000 TEKKIEMEDMLLAEKQGKLAVE-KVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMKRVAREKMELVGELEEPPKTEI 2078
Cdd:PRK03918 508 LEEKLKKYNLEELEKKAEEYEKlKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2079 KEAILRRRRLamhevdlmkkrvsieEKIlaYEDRLlatEEKDAARghlELTREQRICAHEERKLAKATRKLDREKGVSKK 2158
Cdd:PRK03918 588 EELEERLKEL---------------EPF--YNEYL---ELKDAEK---ELEREEKELKKLEEELDKAFEELAETEKRLEE 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2159 PAESRKTLKVLINliskVRKVTQKESKMTKMNRSLLIKEAELSMEEKRLD--IKELEDTEEQPEIIMEERK-LAKMERRL 2235
Cdd:PRK03918 645 LRKELEELEKKYS----EEEYEELREEYLELSRELAGLRAELEELEKRREeiKKTLEKLKEELEEREKAKKeLEKLEKAL 720
|
570 580
....*....|....*....|.
gi 2482565915 2236 AR--QMRRLSTEEKRMAEEEG 2254
Cdd:PRK03918 721 ERveELREKVKKYKALLKERA 741
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1731-2242 |
3.98e-21 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 101.94 E-value: 3.98e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1731 LSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKIN----KVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAK 1806
Cdd:COG1196 237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEelelELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1807 NQEldgqELALKEDELYEEAEKLEDKREALAKEEEMLalyEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQ 1886
Cdd:COG1196 317 RLE----ELEEELAELEEELEELEEELEELEEELEEA---EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1887 ERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIK 1966
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1967 GKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEM-EDMLLAEKQGKLA---------VEKVKLAKEITEVIQNS 2036
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAgavavligvEAAYEAALEAALAAALQ 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2037 QLIREETEIIKEAEELTSEMK--RVAREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAY----- 2109
Cdd:COG1196 550 NIVVEDDEVAAAAIEYLKAAKagRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGrtlva 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2110 --------------EDRLLATEEKDAARGHLELTREQRICAHEERKLAKATRKLDREKGVSKKPAESRKTLKVLINLISK 2175
Cdd:COG1196 630 arleaalrravtlaGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2176 VRKVTQK---ESKMTKMNRSLLIKEAELSMEEKRLDIKELEDTEEQPEIIMEERKLAKMERRLARQMRRL 2242
Cdd:COG1196 710 AEAEEERleeELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1685-2460 |
1.49e-20 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 100.60 E-value: 1.49e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1685 EEEKLAQEERRlaQEEGKLAHEYVKSatkggklahIEMTLGEKetfLSQQEEILSREAeflAQKKKKLARKLEKMAHEKE 1764
Cdd:PTZ00121 1161 EDARKAEEARK--AEDAKKAEAARKA---------EEVRKAEE---LRKAEDARKAEA---ARKAEEERKAEEARKAEDA 1223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1765 KIAKKINKVEEVKavlaQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELY--EEAEKLEDKREA--LAKEE 1840
Cdd:PTZ00121 1224 KKAEAVKKAEEAK----KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARkaDELKKAEEKKKAdeAKKAE 1299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1841 EMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQE---RREKLREQKQRLAQEKERIAQRKTELKVKK 1917
Cdd:PTZ00121 1300 EKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEaakAEAEAAADEAEAAEEKAEAAEKKKEEAKKK 1379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1918 TRLAQMEeslsQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLETYReKLINLSKKLMEEKTVFVAKK--- 1994
Cdd:PTZ00121 1380 ADAAKKK----AEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKK-KADEAKKKAEEAKKADEAKKkae 1454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1995 EKLTVTEKKIEMEDMLLAEKQGKLAVEKVK---LAKEITEVIQNSQLIREETEIIKEAEEL-TSEMKRVARE--KMELVG 2068
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKadeAKKKAEEAKKKADEAKKAAEAKKKADEAkKAEEAKKADEakKAEEAK 1534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2069 ELEEPPKTEIKEAILRRRRlaMHEVDLMKKRVSIEEKILAYEDRLLATEEKDAARGHLELTREQRICAHEERKLAKA--T 2146
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELKK--AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAeeA 1612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2147 RKLDREKGVSKKPAESRKTLKVLINLISKVRKVTQKESKMTKMNRSLLIKEAELSM--EEKRLDIKELEDTEEQPEIIME 2224
Cdd:PTZ00121 1613 KKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKkaEEDKKKAEEAKKAEEDEKKAAE 1692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2225 ERKLAKMERRLARQMRRLSTEEKRMAEEEGQFDWESKQDSEEEVEEEEVEEEEVGEEKVEEEEVGEEEEDLETEKGalff 2304
Cdd:PTZ00121 1693 ALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEK---- 1768
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2305 KRLRIRRKGFMEILPGMEK--FYNLLEQVGHKENFFQDMESLLVEVDKESLSEGEREEAEKDTEAEVEEEEGEEKEEEGE 2382
Cdd:PTZ00121 1769 KAEEIRKEKEAVIEEELDEedEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADA 1848
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2383 EKEEEGEEGEKKEEEGKKEEKGKkegekkeeeekkegekkeeewkeekeqvegeeREKKGKE--IEEWKREKEMEEIEKK 2460
Cdd:PTZ00121 1849 FEKHKFNKNNENGEDGNKEADFN--------------------------------KEKDLKEddEEEIEEADEIEKIDKD 1896
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1727-2398 |
6.58e-18 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 91.74 E-value: 6.58e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1727 KETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKveevKAVLAQKTETMMEKEKNLASEEKKVREEAK 1806
Cdd:PTZ00121 1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKK----KAEDARKAEEARKAEDARKAEEARKAEDAK 1152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1807 NQELDGQelaLKEDELYEEAEKLEDKR--EALAKEEEMLALYEknLSLEEEMLAQEAKHQMEEEKRLA----LEKDRRPE 1880
Cdd:PTZ00121 1153 RVEIARK---AEDARKAEEARKAEDAKkaEAARKAEEVRKAEE--LRKAEDARKAEAARKAEEERKAEearkAEDAKKAE 1227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1881 EVKHLQERREKLREQKQ----------------RLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTER 1944
Cdd:PTZ00121 1228 AVKKAEEAKKDAEEAKKaeeernneeirkfeeaRMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1945 GKALHDKEkkllkgkeQLQDIKGKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMedmllAEKQGKLAVEKVK 2024
Cdd:PTZ00121 1308 KKKAEEAK--------KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEA-----AEEKAEAAEKKKE 1374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2025 LAKEITEVIqnsqliREETEIIKEAEELtsemKRVAREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVsiEE 2104
Cdd:PTZ00121 1375 EAKKKADAA------KKKAEEKKKADEA----KKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA--EE 1442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2105 KILAYEDRLLATEEKDAArgHLELTREQRICAHEERKLAKATRKLDREKgvsKKPAESRKTLKvlinlisKVRKVTQKES 2184
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAE--EAKKKAEEAKKADEAKKKAEEAKKADEAK---KKAEEAKKKAD-------EAKKAAEAKK 1510
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2185 KMTKMNRSLLIKEA-ELSMEEKRLDIKELEDTEEQPEiiMEERKLAKmERRLARQMRRlsTEEKRMAEEEGQFDWESKQD 2263
Cdd:PTZ00121 1511 KADEAKKAEEAKKAdEAKKAEEAKKADEAKKAEEKKK--ADELKKAE-ELKKAEEKKK--AEEAKKAEEDKNMALRKAEE 1585
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2264 SEEEVEEEEVEEEEVGEEKVEEEEVGEEEEDLETEKGALFFKRLRIRRKgfMEILPGMEKfynllEQVGHKENFFQDMES 2343
Cdd:PTZ00121 1586 AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKK--VEQLKKKEA-----EEKKKAEELKKAEEE 1658
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*
gi 2482565915 2344 llVEVDKESLSEGEREEAEKDTEAEveeeegeekeEEGEEKEEEGEEGEKKEEEG 2398
Cdd:PTZ00121 1659 --NKIKAAEEAKKAEEDKKKAEEAK----------KAEEDEKKAAEALKKEAEEA 1701
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1650-2367 |
3.11e-17 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 89.26 E-value: 3.11e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1650 KERRQIRMAQKQARADWRQARGERRRAREKKLLAHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHI-EMTLGEKE 1728
Cdd:pfam02463 279 KEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIkREAEEEEE 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1729 TFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAK-- 1806
Cdd:pfam02463 359 EELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEes 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1807 ---------NQELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNL-SLEEEMLAQEAKHQMEEEKRLALEKD 1876
Cdd:pfam02463 439 ielkqgkltEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSrQKLEERSQKESKARSGLKVLLALIKD 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1877 RRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKV------KKTRLAQMEESLSQERHKLSLEKERLTERGKALHD 1950
Cdd:pfam02463 519 GVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATAdeveerQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLE 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1951 KEKKLLKGKEQLQDIKGKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEIT 2030
Cdd:pfam02463 599 IDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEI 678
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2031 EVIQNSQLIREETEIIKEAEELTSEMKRVAREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYE 2110
Cdd:pfam02463 679 QELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLK 758
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2111 DRllaTEEKDAARGHLELTREQRICAHEErKLAKATRKLDREKGVSKKPAESRKTLKVLINLISKVRKVTQKESKMTKMN 2190
Cdd:pfam02463 759 KE---EKEEEKSELSLKEKELAEEREKTE-KLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEE 834
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2191 RSLLIKEAELSMEEKRLDIKELEDTEEQPEIIMEERKLAKMERRLARQMRRLSTEEKRMAEEEGQFDWESKQDSEEEVEE 2270
Cdd:pfam02463 835 LEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEE 914
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2271 EEVEEEEVGEEKVEEEEVGEEEEDLETEKGALffkrlrirRKGFMEILPGMEKFYNLLEQVGHKENFFQDMESLLVEVDK 2350
Cdd:pfam02463 915 KENEIEERIKEEAEILLKYEEEPEELLLEEAD--------EKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEK 986
|
730
....*....|....*..
gi 2482565915 2351 ESLSEGEREEAEKDTEA 2367
Cdd:pfam02463 987 EERYNKDELEKERLEEE 1003
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1739-2110 |
5.34e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 85.50 E-value: 5.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1739 SREAEFLAQKKKKLARKLEKMAHEKEKIAKKIN----KVEEVKAVLAQKTETMMEkeknlasEEKKVREEAKNQELDGQE 1814
Cdd:TIGR02169 659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSslqsELRRIENRLDELSQELSD-------ASRKIGEIEKEIEQLEQE 731
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1815 LALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEakhqmeEEKRLALEKDRRPEEVKHLQERREKLRE 1894
Cdd:TIGR02169 732 EEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL------EEALNDLEARLSHSRIPEIQAELSKLEE 805
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1895 QKQRlaqekerIAQRKTELKVKKTRLAQMEESLSQERHKLSLE----KERLTERGKALHDKEKKLLKGKEQLQDIKGKLE 1970
Cdd:TIGR02169 806 EVSR-------IEARLREIEQKLNRLTLEKEYLEKEIQELQEQridlKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1971 TYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVekvkLAKEITEVIQNSQLIREETEIIKEAE 2050
Cdd:TIGR02169 879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA----LEEELSEIEDPKGEDEEIPEEELSLE 954
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2051 ELTSEMKRVAREkMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYE 2110
Cdd:TIGR02169 955 DVQAELQRVEEE-IRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYE 1013
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1772-2262 |
1.31e-15 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 83.86 E-value: 1.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1772 KVEEVKAVLAQKTETmmEKEKNLASEEKKVREEAKNQ-ELDGQELALKEDELYEEAEKLEDKREALAKEEEMLalyeknl 1850
Cdd:TIGR00618 161 KSKEKKELLMNLFPL--DQYTQLALMEFAKKKSLHGKaELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHL------- 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1851 sLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRK-------------------- 1910
Cdd:TIGR00618 232 -REALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARkaaplaahikavtqieqqaq 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1911 ---TELKVKKTRLAQ--MEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKK--- 1982
Cdd:TIGR00618 311 rihTELQSKMRSRAKllMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQktt 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1983 LMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMKRVARE 2062
Cdd:TIGR00618 391 LTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKE 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2063 KMELVGELEEPPK--TEIKEAILRRRRLAMHEVDLMKKRVS--IEEKILAYED-----RLLATEEKDAARGH-LELTREQ 2132
Cdd:TIGR00618 471 REQQLQTKEQIHLqeTRKKAVVLARLLELQEEPCPLCGSCIhpNPARQDIDNPgpltrRMQRGEQTYAQLETsEEDVYHQ 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2133 RICAHEERKL--AKATRKLDREKGVSKKPAESRKTLKVLINLISKVRKVTQKESKMTKMNRSLLIKEAELSMEEKRLDIK 2210
Cdd:TIGR00618 551 LTSERKQRASlkEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDV 630
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 2482565915 2211 ELEDTEEQPEIIMEERKLAKMERRLARQMRRLSTEEKRMAEEEgqfDWESKQ 2262
Cdd:TIGR00618 631 RLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKE---LLASRQ 679
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1599-2253 |
1.96e-15 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 83.48 E-value: 1.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1599 ENILHTKSEKELDLGEMFKEGEEEEEEEEEEIGEEEEEEEEEIYEEEAEGRKERRQIRMAQKQARAD----WRQARGERR 1674
Cdd:pfam02463 145 EIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEyyqlKEKLELEEE 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1675 RAREKKLLAHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKKLAR 1754
Cdd:pfam02463 225 YLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLK 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1755 KLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKK---VREEAKNQELDGQELALKEDELYEEAEKLED 1831
Cdd:pfam02463 305 LERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKreaEEEEEEELEKLQEKLEQLEEELLAKKKLESE 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1832 KREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQErREKLREQKQRLAQEKERIAQRKT 1911
Cdd:pfam02463 385 RLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIE-LKQGKLTEEKEELEKQELKLLKD 463
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1912 ELKVKKTRLAQMEESLSQERHKLSLEKER-----LTERGKALHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLMEE 1986
Cdd:pfam02463 464 ELELKKSEDLLKETQLVKLQEQLELLLSRqkleeRSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1987 KTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMKRVAREKMEL 2066
Cdd:pfam02463 544 AISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAK 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2067 VGELEEPPKTEIK--EAILRRRRLAMHEVDLMKKRVSIEEKI---LAYEDRLLATEEKDAARGHLELTREQRICAHE-ER 2140
Cdd:pfam02463 624 VVEGILKDTELTKlkESAKAKESGLRKGVSLEEGLAEKSEVKaslSELTKELLEIQELQEKAESELAKEEILRRQLEiKK 703
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2141 KLAKATRKLDREKGVSKKPAESRKTLKV------LINLISKVRKVTQKESKMTKMNRSLLIKEAELSMEEKRLdIKELED 2214
Cdd:pfam02463 704 KEQREKEELKKLKLEAEELLADRVQEAQdkineeLKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL-AEEREK 782
|
650 660 670
....*....|....*....|....*....|....*....
gi 2482565915 2215 TEEQPEIIMEERKLAKMERRLARQMRRLSTEEKRMAEEE 2253
Cdd:pfam02463 783 TEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQ 821
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1731-2036 |
1.25e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 80.88 E-value: 1.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1731 LSQQEEILSREAE----FLAQKKKK-------LARKLEKMAHEKEKIAKKINKVEEVkavLAQKTETMMEKEKNLASEEK 1799
Cdd:TIGR02169 196 KRQQLERLRREREkaerYQALLKEKreyegyeLLKEKEALERQKEAIERQLASLEEE---LEKLTEEISELEKRLEEIEQ 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1800 KVREEAK--NQELDGQELALKED--ELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEK 1875
Cdd:TIGR02169 273 LLEELNKkiKDLGEEEQLRVKEKigELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1876 DRRPEEVKhlqERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEE---SLSQERHKLSLEKERLTERGKALHDKE 1952
Cdd:TIGR02169 353 DKLTEEYA---ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKReinELKRELDRLQEELQRLSEELADLNAAI 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1953 KKLLKGKEQLQ----DIKGKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIE--MEDMLLAEKQGKLAVEKVKLA 2026
Cdd:TIGR02169 430 AGIEAKINELEeekeDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSklQRELAEAEAQARASEERVRGG 509
|
330
....*....|
gi 2482565915 2027 KEITEVIQNS 2036
Cdd:TIGR02169 510 RAVEEVLKAS 519
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1714-2460 |
1.85e-13 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 76.93 E-value: 1.85e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1714 GGKLAHIEMTlgeKETFLSQQEEILSReaeflAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAvlaQKTETMMEKEKN 1793
Cdd:pfam02463 141 GGKIEIIAMM---KPERRLEIEEEAAG-----SRLKRKKKEALKKLIEETENLAELIIDLEELKL---QELKLKEQAKKA 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1794 LASEEKKVREEAKNQELdgqelaLKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLAL 1873
Cdd:pfam02463 210 LEYYQLKEKLELEEEYL------LYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKL 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1874 EKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEK 1953
Cdd:pfam02463 284 QEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEK 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1954 KLLKGKEQLQDIKGKLETYREKLINlSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVI 2033
Cdd:pfam02463 364 LQEKLEQLEEELLAKKKLESERLSS-AAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELK 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2034 QNSQLIREETEIIKEA--EELTSEMKRVAREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYED 2111
Cdd:pfam02463 443 QGKLTEEKEELEKQELklLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGG 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2112 RLLATEEKDAARGHLELTREQRIC-------------AHEERKLAKATRKLDREKGVSKKPAESRKTLKVLI-------- 2170
Cdd:pfam02463 523 RIISAHGRLGDLGVAVENYKVAIStavivevsatadeVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIavleidpi 602
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2171 -NLISKVRKVTQKESKMTKMNRSLLI----KEAELSMEEKRLDIKELEDTEEQPEIIMEERKLAKMErrLARQMRRLSTE 2245
Cdd:pfam02463 603 lNLAQLDKATLEADEDDKRAKVVEGIlkdtELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLS--ELTKELLEIQE 680
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2246 EKRMAEEEGQFDWESKQDsEEEVEEEEVEEEEVGEEKVEEEEVGEEEEDLETEKGALFFKRLRIRRKGFMEILpgmEKFY 2325
Cdd:pfam02463 681 LQEKAESELAKEEILRRQ-LEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEE---EKSR 756
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2326 NLLEQVGHKENFFQDMESLLVEVDKESLSEGEREEAEKDTEAEVEEEEGEEKEEEGEEKEEEGEEGEKKEEEGKKEEKGK 2405
Cdd:pfam02463 757 LKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELE 836
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*
gi 2482565915 2406 KEGEKKEEEEKKEGEKKEEEWKEEKEQVEGEEREKKGKEIEEWKREKEMEEIEKK 2460
Cdd:pfam02463 837 ELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESK 891
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1796-2122 |
1.14e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 74.33 E-value: 1.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1796 SEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKREalaKEEEMLALYEKNLSLEEEMLAQEaKHQMEEEKRlALEK 1875
Cdd:TIGR02169 170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERE---KAERYQALLKEKREYEGYELLKE-KEALERQKE-AIER 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1876 DRRPEEvKHLQERREKLREQKQRLAQEKERIAQRKTELKVK--------KTRLAQMEESLSQERHKLSLEKERLTERGKA 1947
Cdd:TIGR02169 245 QLASLE-EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeqlrvKEKIGELEAEIASLERSIAEKERELEDAEER 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1948 LHDKEKKLLKGKEQLQDIKGKLETYREKLInlskKLMEEktvFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAK 2027
Cdd:TIGR02169 324 LAKLEAEIDKLLAEIEELEREIEEERKRRD----KLTEE---YAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2028 ---EITEVIQN-SQLIREETEIIKEAEELTSEMKRVAREKMELVGELEEPPKtEIKEAILRRRRLAMHEVDLMKKRVSIE 2103
Cdd:TIGR02169 397 lkrEINELKRElDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL-EIKKQEWKLEQLAADLSKYEQELYDLK 475
|
330
....*....|....*....
gi 2482565915 2104 EKILAYEDRLLATEEKDAA 2122
Cdd:TIGR02169 476 EEYDRVEKELSKLQRELAE 494
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1736-2256 |
1.41e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.94 E-value: 1.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1736 EILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKIN----KVEEVKAVLAQKTETMMEKEKNLAS-----EEKKVREEAK 1806
Cdd:TIGR02168 228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQeleeKLEELRLEVSELEEEIEELQKELYAlaneiSRLEQQKQIL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1807 NQELDG--QELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNL-SLEEEMLAQEAKHQMEEEKRLALEK--DRRPEE 1881
Cdd:TIGR02168 308 RERLANleRQLEELEAQLEELESKLDELAEELAELEEKLEELKEELeSLEAELEELEAELEELESRLEELEEqlETLRSK 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1882 VKHLQERREKLREQKQRLAQEKERIAQRKTELK------VKKTRLAQMEE------SLSQERHKLSLEKERLTERGKALH 1949
Cdd:TIGR02168 388 VAQLELQIASLNNEIERLEARLERLEDRRERLQqeieelLKKLEEAELKElqaeleELEEELEELQEELERLEEALEELR 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1950 DKEKKLLKGKEQ--------------LQDIKGKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEK-KIEMEdMLLAEK 2014
Cdd:TIGR02168 468 EELEEAEQALDAaerelaqlqarldsLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyEAAIE-AALGGR 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2015 QGKLAVEKVKLAKEITEVIQNSQLIR---------EETEIIKEAEELTSEMKRVAREKMELVGELEEPPK---------- 2075
Cdd:TIGR02168 547 LQAVVVENLNAAKKAIAFLKQNELGRvtflpldsiKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvl 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2076 --TEIKEAILRRRRLAMHEV------DLMKKRVSI-------EEKILAYEDRLL-ATEEKDAARGHLELTREQRICAHEE 2139
Cdd:TIGR02168 627 vvDDLDNALELAKKLRPGYRivtldgDLVRPGGVItggsaktNSSILERRREIEeLEEKIEELEEKIAELEKALAELRKE 706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2140 -RKLAKATRKLDREKgvSKKPAESRKTLKVLINLISKVRKVTQKESkmtkmNRSLLIKEAELSMEEKRLDIkeledTEEQ 2218
Cdd:TIGR02168 707 lEELEEELEQLRKEL--EELSRQISALRKDLARLEAEVEQLEERIA-----QLSKELTELEAEIEELEERL-----EEAE 774
|
570 580 590
....*....|....*....|....*....|....*...
gi 2482565915 2219 PEIIMEERKLAKMERRLARQMRRLSTEEKRMAEEEGQF 2256
Cdd:TIGR02168 775 EELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL 812
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1652-2252 |
3.56e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.78 E-value: 3.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1652 RRQIRMAQKQAR-ADWRQARGERRRAREKKLLAHEEEKLAQEERRLAQEEGKLAHEYVKSAT----KGGKLAHIEMTLGE 1726
Cdd:TIGR02168 199 ERQLKSLERQAEkAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAelqeLEEKLEELRLEVSE 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1727 KE--------TFLSQQEEI--LSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTEtmmEKEKNLAS 1796
Cdd:TIGR02168 279 LEeeieelqkELYALANEIsrLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE---ELKEELES 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1797 EEKKVreEAKNQELDGQELALKEDElyeeaEKLEDKREALAKEEEMLALYEKNLS-LEEEMLAQEAKHQMEEEKRLALEK 1875
Cdd:TIGR02168 356 LEAEL--EELEAELEELESRLEELE-----EQLETLRSKVAQLELQIASLNNEIErLEARLERLEDRRERLQQEIEELLK 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1876 DRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEK---ERLTERGKALHDKE 1952
Cdd:TIGR02168 429 KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLdslERLQENLEGFSEGV 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1953 KKLLKGKEQLQDIKG----------KLETYREKLI--NLSKKLMEEKTV------FVAKKEKLTVT--------EKKIEM 2006
Cdd:TIGR02168 509 KALLKNQSGLSGILGvlselisvdeGYEAAIEAALggRLQAVVVENLNAakkaiaFLKQNELGRVTflpldsikGTEIQG 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2007 EDMLLAEKQGK---LAVEKVKLAKEITEVIQN------------------SQLIREETEIIKEAE--------------- 2050
Cdd:TIGR02168 589 NDREILKNIEGflgVAKDLVKFDPKLRKALSYllggvlvvddldnalelaKKLRPGYRIVTLDGDlvrpggvitggsakt 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2051 -----ELTSEMKRVaREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRLLATE------EK 2119
Cdd:TIGR02168 669 nssilERRREIEEL-EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEaeveqlEE 747
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2120 DAARGHLELTREQRICAHEERKLAKATRKLDREKGVSKKPAESRKTLKVLINLISkvRKVTQKESKMTKMNRSLLIKEAE 2199
Cdd:TIGR02168 748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR--EALDELRAELTLLNEEAANLRER 825
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*
gi 2482565915 2200 LSMEEKRLD--IKELEDTEEQPEIIMEERKlakmerRLARQMRRLSTEEKRMAEE 2252
Cdd:TIGR02168 826 LESLERRIAatERRLEDLEEQIEELSEDIE------SLAAEIEELEELIEELESE 874
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1750-2183 |
5.10e-12 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 71.72 E-value: 5.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1750 KKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLasEEKKVREEAKNQELDGQELALKEDELYEEAEKL 1829
Cdd:COG4717 60 KPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL--EELEAELEELREELEKLEKLLQLLPLYQELEAL 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1830 EDKREALAKE-EEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQ 1908
Cdd:COG4717 138 EAELAELPERlEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEE 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1909 RKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKA-LHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLMEEK 1987
Cdd:COG4717 218 AQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREK 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1988 TVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQN----SQLIREETEIIKEAEELTSEMKRVA--- 2060
Cdd:COG4717 298 ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRieelQELLREAEELEEELQLEELEQEIAAlla 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2061 -----------------REKMELVGELEEppkteiKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRLLATEEKdaar 2123
Cdd:COG4717 378 eagvedeeelraaleqaEEYQELKEELEE------LEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEE---- 447
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2482565915 2124 gHLELTREQRICAHE------ERKLAKATRKLDREKGVSKKPAESRKTLKVLINLISKVRKVTQKE 2183
Cdd:COG4717 448 -LEELREELAELEAEleqleeDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1682-1917 |
5.63e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 72.02 E-value: 5.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1682 LAHEEEKLAQEERRLAQEEGKLAHEYVKsaTKGGKLAHIEMTLGEKETFLSQQEEILSR---EAEFLAQKKKKLARKLEK 1758
Cdd:TIGR02169 767 IEELEEDLHKLEEALNDLEARLSHSRIP--EIQAELSKLEEEVSRIEARLREIEQKLNRltlEKEYLEKEIQELQEQRID 844
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1759 MAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDK----RE 1834
Cdd:TIGR02169 845 LKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRlselKA 924
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1835 ALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRR---------PEEVKHLQERREKLREQKQRLAQEKER 1905
Cdd:TIGR02169 925 KLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRalepvnmlaIQEYEEVLKRLDELKEKRAKLEEERKA 1004
|
250
....*....|..
gi 2482565915 1906 IAQRKTELKVKK 1917
Cdd:TIGR02169 1005 ILERIEEYEKKK 1016
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1726-1948 |
3.19e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 69.30 E-value: 3.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1726 EKETFLSQQEEILSREAEflAQKKKKLARKLEKMAHEKEKIAKKInkvEEVKAVLAQKTETMMEKEKN---LASEEKKVR 1802
Cdd:PRK02224 483 ELEDLEEEVEEVEERLER--AEDLVEAEDRIERLEERREDLEELI---AERRETIEEKRERAEELRERaaeLEAEAEEKR 557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1803 EEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEEEMLAL---YEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRP 1879
Cdd:PRK02224 558 EAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAiadAEDEIERLREKREALAELNDERRERLAEKRERKR 637
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2482565915 1880 E-EVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQ---MEESLSQERHKLSLEKERLTERGKAL 1948
Cdd:PRK02224 638 ElEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAeigAVENELEELEELRERREALENRVEAL 710
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1716-2256 |
6.57e-11 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 68.53 E-value: 6.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1716 KLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLaQKTETMMEKEKNLA 1795
Cdd:TIGR00606 190 TLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRL-KEIEHNLSKIMKLD 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1796 SEEKKVREEAKNQELDGQELALKEDELY----EEAEKLED--KREALAKEEEMLALYEK--NLSLEEEMLAQEAKHQMEE 1867
Cdd:TIGR00606 269 NEIKALKSRKKQMEKDNSELELKMEKVFqgtdEQLNDLYHnhQRTVREKERELVDCQREleKLNKERRLLNQEKTELLVE 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1868 EKRLALEKDRRPEEVKHLQERREKLREQ-----------------------KQRLAQEKERIAQRKTEL----KVKKTRL 1920
Cdd:TIGR00606 349 QGRLQLQADRHQEHIRARDSLIQSLATRleldgfergpfserqiknfhtlvIERQEDEAKTAAQLCADLqskeRLKQEQA 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1921 AQMEESLSQERHKLSLEKERLTERGKALhdkekklLKGKEQLQDIKGKLETYREKLINLSKKLMEektvfVAKKEKLTVT 2000
Cdd:TIGR00606 429 DEIRDEKKGLGRTIELKKEILEKKQEEL-------KFVIKELQQLEGSSDRILELDQELRKAERE-----LSKAEKNSLT 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2001 EKKIeMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMKRV-AREKMELVGELEEPPKTEIK 2079
Cdd:TIGR00606 497 ETLK-KEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIkSRHSDELTSLLGYFPNKKQL 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2080 EAILRRRRlamHEVDLMKKRV----------------------SIEEKILAYEDRLLATEEKDAARGHLELTREQRICAH 2137
Cdd:TIGR00606 576 EDWLHSKS---KEINQTRDRLaklnkelasleqnknhinneleSKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSS 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2138 EERKLAKATRKLdREKGVSKKPAESRKTLKVLINLISKVRKVTQKESKMTKMNRSLLIK----EAELSMEEKRLDIKELE 2213
Cdd:TIGR00606 653 KQRAMLAGATAV-YSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKlkstESELKKKEKRRDEMLGL 731
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 2482565915 2214 DTEEQPEIIMEERKLAKMERRLARQMRRLSTEEKRMAEEEGQF 2256
Cdd:TIGR00606 732 APGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL 774
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1406-2153 |
9.12e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 68.07 E-value: 9.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1406 EKEEGLQEAEEETQEKDKEKEVAFLESEDVVKGK-RRPRKGRKTRKTVKQEKMEKDERIEETISAEELAVTLKPEEVAEE 1484
Cdd:pfam02463 278 EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDdEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEE 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1485 GEgrSKKRKGTWEEEEGAEKREKEEEEEQMIEPKEAITEAVERKLSwVEWKSHWDEWQKAQTQRAVLWEDWKKQCDKKHF 1564
Cdd:pfam02463 358 EE--ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS-EEEKEAQLLLELARQLEDLLKEEKKEELEILEE 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1565 EEEARLRVEGKLQpSEEVEEPKKMLTWDEWREVWENILHTKSEKELDLGEMFKEGEEEEEEEEEEIGEEEEEEEEEIYEE 1644
Cdd:pfam02463 435 EEESIELKQGKLT-EEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLL 513
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1645 EAEGRKE-RRQIRMAQKQARADWRQARGERRRAREKKLLAHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHIEMT 1723
Cdd:pfam02463 514 ALIKDGVgGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS 593
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1724 LGEKETFLSQQEEILSREA--EFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKV 1801
Cdd:pfam02463 594 IAVLEIDPILNLAQLDKATleADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTK 673
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1802 REEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALyEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEE 1881
Cdd:pfam02463 674 ELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKL-EAEELLADRVQEAQDKINEELKLLKQKIDEEEEEE 752
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1882 VKHLQERREKLREQKQRLAQEKERIAQRKTELKV-----KKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLL 1956
Cdd:pfam02463 753 EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLkveeeKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKE 832
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1957 KGKEQLQDIKGKLETYREKLINLSKKLMEEKTVfvaKKEKLTVTEKKIEMEDMLLAEKqgklavEKVKLAKEITEVIQNS 2036
Cdd:pfam02463 833 EELEELALELKEEQKLEKLAEEELERLEEEITK---EELLQELLLKEEELEEQKLKDE------LESKEEKEKEEKKELE 903
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2037 QLIREETEIIKEAEELTSEMKRVAREKMELVGELEEPPKTEIKEAILRR--RRLAMHEVDLMKKRVSIEEKILAYEDRLL 2114
Cdd:pfam02463 904 EESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEEnnKEEEEERNKRLLLAKEELGKVNLMAIEEF 983
|
730 740 750
....*....|....*....|....*....|....*....
gi 2482565915 2115 ATEEKDAARGHLELTREQRicahEERKLAKATRKLDREK 2153
Cdd:pfam02463 984 EEKEERYNKDELEKERLEE----EKKKLIRAIIEETCQR 1018
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1816-2131 |
1.56e-10 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 67.07 E-value: 1.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1816 ALKEDELYEEAEKLEDKREALAKEEEMLALyEKNLSLEEEMLAQEAKHQME-----EEKRLALEKDRRPEEVKHLQERRE 1890
Cdd:pfam17380 283 AVSERQQQEKFEKMEQERLRQEKEEKAREV-ERRRKLEEAEKARQAEMDRQaaiyaEQERMAMERERELERIRQEERKRE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1891 KLREQKQRLAQEKERIaqRKTElkvkktRLaQMEESLSQERHKLSLE---KERLTERgkalhDKEKKLLKGKEQLQDIKG 1967
Cdd:pfam17380 362 LERIRQEEIAMEISRM--RELE------RL-QMERQQKNERVRQELEaarKVKILEE-----ERQRKIQQQKVEMEQIRA 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1968 KLETYREKLInlsKKLMEEKtvfvaKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEviQNSQLIREETEII- 2046
Cdd:pfam17380 428 EQEEARQREV---RRLEEER-----AREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEK--RDRKRAEEQRRKIl 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2047 -KEAEELTSEMKRVAREKMELVGELEEPPKTEIKEailRRRRLAMHEvdlMKKRVSIEEKILAYEDRLLATEEK---DAA 2122
Cdd:pfam17380 498 eKELEERKQAMIEEERKRKLLEKEMEERQKAIYEE---ERRREAEEE---RRKQQEMEERRRIQEQMRKATEERsrlEAM 571
|
....*....
gi 2482565915 2123 RGHLELTRE 2131
Cdd:pfam17380 572 EREREMMRQ 580
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1682-1995 |
1.57e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.39 E-value: 1.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1682 LAHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHIEMTLGEKETFLSQQEEILSREaeflaqkKKKLARKLEKMAH 1761
Cdd:TIGR02168 679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL-------EAEVEQLEERIAQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1762 EKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEEE 1841
Cdd:TIGR02168 752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1842 MLALYEKNLsleeEMLAQEAKHQMEEEKRLAlekdrrpEEVKHLQERREKLREQKQRLAQEKERIAQRkteLKVKKTRLA 1921
Cdd:TIGR02168 832 RIAATERRL----EDLEEQIEELSEDIESLA-------AEIEELEELIEELESELEALLNERASLEEA---LALLRSELE 897
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 1922 QMEESLSQERHKLSLEKERLTERGKALHDKEKkllkgkeQLQDIKGKLETYREKLINLSKKLMEEKTVFVAKKE 1995
Cdd:TIGR02168 898 ELSEELRELESKRSELRRELEELREKLAQLEL-------RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIE 964
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1737-1970 |
2.74e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 65.17 E-value: 2.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1737 ILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMmekEKNLASEEKKVREEAKNQELDGQELA 1816
Cdd:COG4942 10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL---ERRIAALARRIRALEQELAALEAELA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1817 LKEDELYEEAEKLEDKREALAkeeEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKdrrpEEVKHLQERREKLREQK 1896
Cdd:COG4942 87 ELEKEIAELRAELEAQKEELA---ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLK----YLAPARREQAEELRADL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 1897 QRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLE 1970
Cdd:COG4942 160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1712-2214 |
3.04e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 66.20 E-value: 3.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1712 TKGGKLAHIEMTLGEKETFLSQQEEilsrEAEFLAQKKKKLARKLEKmahEKEKIAKKINKVEEVKAVLAQKTETMMEKE 1791
Cdd:TIGR04523 51 NKEKELKNLDKNLNKDEEKINNSNN----KIKILEQQIKDLNDKLKK---NKDKINKLNSDLSKINSEIKNDKEQKNKLE 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1792 KNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQeAKHQMEEEKRL 1871
Cdd:TIGR04523 124 VELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDK-IKNKLLKLELL 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1872 ALEKDRRPEEVKHLQERREKLREQKQRLaqeKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDK 1951
Cdd:TIGR04523 203 LSNLKKKIQKNKSLESQISELKKQNNQL---KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1952 EKKLLKGKEQLQDIKGKLETYR-EKLINLSKKLMEEKTvfvAKKEKLTVTEKKI--------EMEDML--LAEKQGKLAV 2020
Cdd:TIGR04523 280 NKKIKELEKQLNQLKSEISDLNnQKEQDWNKELKSELK---NQEKKLEEIQNQIsqnnkiisQLNEQIsqLKKELTNSES 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2021 EKVKLAKEITE-VIQNSQLIREETEIIKEAEELTSEmKRVAREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKR 2099
Cdd:TIGR04523 357 ENSEKQRELEEkQNEIEKLKKENQSYKQEIKNLESQ-INDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETI 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2100 VSIEEKI--LAYEDRLLATEEKDaarghLELTREQricahEERKLAKATRKLDREK-GVSKKPAESRKTLKVLINLISKV 2176
Cdd:TIGR04523 436 IKNNSEIkdLTNQDSVKELIIKN-----LDNTRES-----LETQLKVLSRSINKIKqNLEQKQKELKSKEKELKKLNEEK 505
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 2482565915 2177 RKVTQKESKMTKMNRSLLIKEAELSME--EKRLDIKELED 2214
Cdd:TIGR04523 506 KELEEKVKDLTKKISSLKEKIEKLESEkkEKESKISDLED 545
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
275-634 |
3.32e-10 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 63.89 E-value: 3.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 275 SLHSFRAHPTVVVCIQSRAEPHTLLTAGKEGIIKEWNLTSGDLLRHLKLgeelyalqfidnttffcqttHQFSLRRlpgf 354
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKG--------------------HTGPVRD---- 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 355 yslfnicgsipqqlrrIRCGNNWYRILCATEDGLLRFVSPVTGDLLlitwpFSVLDHA---VDWAYDPNKEeLFVATGT- 430
Cdd:cd00200 57 ----------------VAASADGTYLASGSSDKTIRLWDLETGECV-----RTLTGHTsyvSSVAFSPDGR-ILSSSSRd 114
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 431 SEVLVFDASRNPCpvKYLLctsPDIQDYVQCLAYgnfhlgRGLEGLMFSGHQSGMIRV--LSQHSC-ARIEKnvHFGAVL 507
Cdd:cd00200 115 KTIKVWDVETGKC--LTTL---RGHTDWVNSVAF------SPDGTFVASSSQDGTIKLwdLRTGKCvATLTG--HTGEVN 181
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 508 ALSIfygglmtSRENSLLCSYGVDDYIQLSEaVLTGArlQLKTL------ACILSSCPLKHLVllpkAVGAITSTncLRL 581
Cdd:cd00200 182 SVAF-------SPDGEKLLSSSSDGTIKLWD-LSTGK--CLGTLrghengVNSVAFSPDGYLL----ASGSEDGT--IRV 245
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 2482565915 582 WKLREFisfgssqgiKFIETLPLHQCPITSFDVCLSLNVFATGGSDGTVRLWD 634
Cdd:cd00200 246 WDLRTG---------ECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1820-2032 |
3.72e-10 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 66.09 E-value: 3.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1820 DELYEEAEKLEDKREALakeEEMLALYEKNLSLEEEMLAQEAkhqmeEEKRLALEKDRRpeEVKHLQERREKLREQKQRL 1899
Cdd:COG4913 238 ERAHEALEDAREQIELL---EPIRELAERYAAARERLAELEY-----LRAALRLWFAQR--RLELLEAELEELRAELARL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1900 AQEKERIAQRKTELKVKKTRL-AQMEESLSQERHKLSLEKERLTErgkalhdkekkllkgkeQLQDIKGKLETYREKLIN 1978
Cdd:COG4913 308 EAELERLEARLDALREELDELeAQIRGNGGDRLEQLEREIERLER-----------------ELEERERRRARLEALLAA 370
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 1979 LSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEV 2032
Cdd:COG4913 371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL 424
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1821-2364 |
5.08e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 65.47 E-value: 5.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1821 ELYEEAEK--LEDKREALAKEEEmlalYEKNLSLEEEMlaQEAKHQMEEEKRLALEK-DRRPEEVKHLQERREKLREQKQ 1897
Cdd:PRK03918 158 DDYENAYKnlGEVIKEIKRRIER----LEKFIKRTENI--EELIKEKEKELEEVLREiNEISSELPELREELEKLEKEVK 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1898 RLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTErgkalhdkekkLLKGKEQLQDIKGKLETYReKLI 1977
Cdd:PRK03918 232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEE-----------LEEKVKELKELKEKAEEYI-KLS 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1978 NLSKKLMEEKTVFVAKKEKLT-----VTEKKIEMEDMllAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIKEAEEL 2052
Cdd:PRK03918 300 EFYEEYLDELREIEKRLSRLEeeingIEERIKELEEK--EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERL 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2053 TSEMKRVAREKMELVGELEEPPKTEIKEAILRrrrlamhevdLMKKRVSIEEKIlayEDRLLATEEKDAARGHLELTREQ 2132
Cdd:PRK03918 378 KKRLTGLTPEKLEKELEELEKAKEEIEEEISK----------ITARIGELKKEI---KELKKAIEELKKAKGKCPVCGRE 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2133 RICAHEERKLAKATRKLdreKGVSKKPAESRKTLKVLINLISKVRKVTQKESKMTKMnRSLLIKEAELSMEEKRLDIKEL 2212
Cdd:PRK03918 445 LTEEHRKELLEEYTAEL---KRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL-KELAEQLKELEEKLKKYNLEEL 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2213 EDTEEQPEIIMEE-RKLAKMERRLARQMRRLSTEEKRMAEEEGQFDWESKQDSEEEVeeeeveeeevgeekveeeevgee 2291
Cdd:PRK03918 521 EKKAEEYEKLKEKlIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLK----------------------- 577
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2482565915 2292 eedletekgalffkrlRIRRKGFmeilpgmEKFYNLLEQVGHKENFFQDMESLlvevdKESLSEGEREEAEKD 2364
Cdd:PRK03918 578 ----------------ELEELGF-------ESVEELEERLKELEPFYNEYLEL-----KDAEKELEREEKELK 622
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1827-2161 |
7.95e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.09 E-value: 7.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1827 EKLEDKREALAKEEEMLalyEKNLSLEEEMLAQEAKHQMEEEKRL---ALEKDRRPEEVKHLQERREKLREQKQRLAQEK 1903
Cdd:TIGR02169 170 RKKEKALEELEEVEENI---ERLDLIIDEKRQQLERLRREREKAEryqALLKEKREYEGYELLKEKEALERQKEAIERQL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1904 ERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTErgkalhdkeKKLLKGKEQLQDIKGKLETYREKlINLSKKL 1983
Cdd:TIGR02169 247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE---------EEQLRVKEKIGELEAEIASLERS-IAEKERE 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1984 MEEKTVFVAKKEKLtVTEKKIEMEDmlLAEKQGKLAVEKVKLAKEITEviqnsqLIREETEIIKEAEELTSEMKRVAREK 2063
Cdd:TIGR02169 317 LEDAEERLAKLEAE-IDKLLAEIEE--LEREIEEERKRRDKLTEEYAE------LKEELEDLRAELEEVDKEFAETRDEL 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2064 MELVGELEEPpKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRL--LATEEKD------AARGHLELTREQRic 2135
Cdd:TIGR02169 388 KDYREKLEKL-KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIneLEEEKEDkaleikKQEWKLEQLAADL-- 464
|
330 340
....*....|....*....|....*..
gi 2482565915 2136 AHEERKLAKATRKLDR-EKGVSKKPAE 2161
Cdd:TIGR02169 465 SKYEQELYDLKEEYDRvEKELSKLQRE 491
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
1649-1905 |
1.04e-09 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 64.12 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1649 RKERRQIRMAQKQARAdwrqARGERRRAREKKLLAHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHIEMTLGEKE 1728
Cdd:pfam02029 71 REERRQKRLQEALERQ----KEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWS 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1729 TFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQ 1808
Cdd:pfam02029 147 TEVRQAEEEGEEEEDKSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLKVTTKRR 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1809 ELDGQELALKEDE---LYEEAEKLEDKREALAK--EEEMLALYEKNLSLEEEMlaQEAKHQMEEEKRLALEKDRRPEEVK 1883
Cdd:pfam02029 227 QGGLSQSQEREEEaevFLEAEQKLEELRRRRQEkeSEEFEKLRQKQQEAELEL--EELKKKREERRKLLEEEEQRRKQEE 304
|
250 260
....*....|....*....|..
gi 2482565915 1884 HLQERREKlrEQKQRLAQEKER 1905
Cdd:pfam02029 305 AERKLREE--EEKRRMKEEIER 324
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1389-2256 |
1.18e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 64.61 E-value: 1.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1389 EEVTGQEEMPEAGKQRLEKEEGlqeaeeeTQEKDKEKEVAFLESEDVVK--GKRRPRKGRKTRKTVKQEKMEKDERIEET 1466
Cdd:pfam02463 159 EEEAAGSRLKRKKKEALKKLIE-------ETENLAELIIDLEELKLQELklKEQAKKALEYYQLKEKLELEEEYLLYLDY 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1467 ISAEELAVTLKPEEVAEEGEGRSKKRKGTWEEEEGAEKREKEEEEEQMIEP--------KEAITEAVERKLSWVEWKSHW 1538
Cdd:pfam02463 232 LKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKlqeeelklLAKEEEELKSELLKLERRKVD 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1539 DEWQKAQTQRAVLWEDWKKQCDKKHFEEEARLRVEGKLQPSEEVEEPKKMLtwdEWREVWENILHTKSEKELDLGEMFKE 1618
Cdd:pfam02463 312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELE---KLQEKLEQLEEELLAKKKLESERLSS 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1619 GEEEEEEEEEEIGEEEEEEEEEIYEEEaegRKERRQIRMAQKQARADWRQARGERRRAREKKLLAHEEEKLAQEERRLAQ 1698
Cdd:pfam02463 389 AAKLKEEELELKSEEEKEAQLLLELAR---QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1699 EEGKLAHEYVKSATKGGKLAHIEMTLGEKETFLSQQE-EILSREAEFLAQKKKKLARKLEKMAHEKEKIA---------- 1767
Cdd:pfam02463 466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKEsKARSGLKVLLALIKDGVGGRIISAHGRLGDLGvavenykvai 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1768 --KKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLE--------DKREALA 1837
Cdd:pfam02463 546 stAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKatleadedDKRAKVV 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1838 KEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKK 1917
Cdd:pfam02463 626 EGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKE 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1918 TRLAQMEESLSQERHKL-----SLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLMEEKTVFVA 1992
Cdd:pfam02463 706 QREKEELKKLKLEAEELladrvQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEK 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1993 KKEKLTVTEKKIEMEDMLLAEKQGKLAVEKvklAKEITEVIQNSQLIREETEIIKEAEELTSEMKRvareKMELVGELEE 2072
Cdd:pfam02463 786 LKVEEEKEEKLKAQEEELRALEEELKEEAE---LLEEEQLLIEQEEKIKEEELEELALELKEEQKL----EKLAEEELER 858
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2073 PPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRLLAtEEKDAARGHLELTREQRICAHEERKLAKATRKLDRE 2152
Cdd:pfam02463 859 LEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKE-LEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEP 937
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2153 KGVSKKPAESRKTLKVLI--NLISKVRKVTQKESKMTKMNRSLLIKEAELSMEEKR---LDIKELEDTEEQPEIIMEERK 2227
Cdd:pfam02463 938 EELLLEEADEKEKEENNKeeEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDeleKERLEEEKKKLIRAIIEETCQ 1017
|
890 900
....*....|....*....|....*....
gi 2482565915 2228 LAKMERRLARQMRRLSTEEKRMAEEEGQF 2256
Cdd:pfam02463 1018 RLKEFLELFVSINKGWNKVFFYLELGGSA 1046
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1824-2127 |
1.20e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.31 E-value: 1.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1824 EEAE-KLEDKREALAKEEEMLALYEKNL-SLEEEM-LAQEAKHQMEEEKRLAL------------EKDRRPEEVKHLQER 1888
Cdd:TIGR02168 175 KETErKLERTRENLDRLEDILNELERQLkSLERQAeKAERYKELKAELRELELallvlrleelreELEELQEELKEAEEE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1889 REKLREQKQRLAQE-----------KERIAQRKTELKvkktrlaqmeeSLSQERHKLSLEKERLTERGKALHDkekKLLK 1957
Cdd:TIGR02168 255 LEELTAELQELEEKleelrlevselEEEIEELQKELY-----------ALANEISRLEQQKQILRERLANLER---QLEE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1958 GKEQLQDIKGKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMedmlLAEKQGKLAVEKVKLAKEITEVIQNSQ 2037
Cdd:TIGR02168 321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE----LESRLEELEEQLETLRSKVAQLELQIA 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2038 LIREETEIIKeaEELTSEMKRVAREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRL-LAT 2116
Cdd:TIGR02168 397 SLNNEIERLE--ARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELeEAE 474
|
330
....*....|.
gi 2482565915 2117 EEKDAARGHLE 2127
Cdd:TIGR02168 475 QALDAAERELA 485
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1649-1945 |
9.19e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.61 E-value: 9.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1649 RKERRQIRMAQKQARADWRQARGERRRAreKKLLAHEEEKLAQEERRLAQEEGKLAHeyvksatkggklahiemtLGEKE 1728
Cdd:TIGR02168 704 RKELEELEEELEQLRKELEELSRQISAL--RKDLARLEAEVEQLEERIAQLSKELTE------------------LEAEI 763
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1729 TFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVE----EVKAVLAQKTETMMEKEKNLASEEKKVREE 1804
Cdd:TIGR02168 764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRaeltLLNEEAANLRERLESLERRIAATERRLEDL 843
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1805 AknqeldgQELALKEDELYEEAEKLEDKREALAKEEEML-ALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRP--EE 1881
Cdd:TIGR02168 844 E-------EQIEELSEDIESLAAEIEELEELIEELESELeALLNERASLEEALALLRSELEELSEELRELESKRSElrRE 916
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2482565915 1882 VKHLQERREKLREQKQRLAQEKERIAQR-----KTELKVKKTRLAQMEESLSQERHKLSLEKERLTERG 1945
Cdd:TIGR02168 917 LEELREKLAQLELRLEGLEVRIDNLQERlseeySLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1384-1868 |
1.03e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 61.70 E-value: 1.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1384 EEATR--EEVTGQEEMPEAG--KQRLEKEEGLQEAEEETQEKDKEKEVAFLESEDVVKGKRRPRKGRKTRKTVKQEKMEK 1459
Cdd:PTZ00121 1447 DEAKKkaEEAKKAEEAKKKAeeAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1460 DERIEETISAEELAvtlKPEEVAEEGEGRSKKRKGTWEEEEGAEKREKEEEEEQMIEPKEAITEAVERKlSWVEWKSHWD 1539
Cdd:PTZ00121 1527 AKKAEEAKKADEAK---KAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA-RIEEVMKLYE 1602
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1540 EWQKAQTQRAVLWEDWKKQCDKKHFEEEARLRVEG-KLQPSEEVEEPKKMLTWDEWREVWENILHTKSEKELDLGEMFKE 1618
Cdd:PTZ00121 1603 EEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK 1682
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1619 GEEEEEEeeeeigeeeeeeeeeiyeeeaegrKERRQIRMAQKQARADWRQARGERRRAREKKLLAHEEEKL--AQEERRL 1696
Cdd:PTZ00121 1683 AEEDEKK------------------------AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKikAEEAKKE 1738
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1697 AQEEGKLAHEYVKSATKGGKLAHIEMTLGEKETFLSQQEEILSREAefLAQKKKKLARKLEKMAHE-KEKIAKKINKVEE 1775
Cdd:PTZ00121 1739 AEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE--LDEEDEKRRMEVDKKIKDiFDNFANIIEGGKE 1816
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1776 VKAVLAQKTETMMEKEKNLASEEKKVREEAKNQEldgQELALKEDELYEEAEKLEDkreaLAKEEEMLALYEKNLsLEEE 1855
Cdd:PTZ00121 1817 GNLVINDSKEMEDSAIKEVADSKNMQLEEADAFE---KHKFNKNNENGEDGNKEAD----FNKEKDLKEDDEEEI-EEAD 1888
|
490
....*....|...
gi 2482565915 1856 MLAQEAKHQMEEE 1868
Cdd:PTZ00121 1889 EIEKIDKDDIERE 1901
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1685-1910 |
1.23e-08 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 60.91 E-value: 1.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1685 EEEKLAQE-ER---RLAQEEGKLAHEYVKS---ATKGGKLAHIEMTLGEKEtflsQQEEILSREAEflAQKKKKL----- 1752
Cdd:pfam17380 338 EQERMAMErEReleRIRQEERKRELERIRQeeiAMEISRMRELERLQMERQ----QKNERVRQELE--AARKVKIleeer 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1753 ARKLEKMAHEKEKIAKKINKVEEVKA-VLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELAL-KEDELYEEAEKLE 1830
Cdd:pfam17380 412 QRKIQQQKVEMEQIRAEQEEARQREVrRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLeLEKEKRDRKRAEE 491
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1831 DKREALAKEEE-----MLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRP---EEVKHLQERREKLREQKQRL-AQ 1901
Cdd:pfam17380 492 QRRKILEKELEerkqaMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQqemEERRRIQEQMRKATEERSRLeAM 571
|
....*....
gi 2482565915 1902 EKERIAQRK 1910
Cdd:pfam17380 572 EREREMMRQ 580
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
242-637 |
1.57e-08 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 59.92 E-value: 1.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 242 SPITCCFTSLEENLLYAGNKVGEVYVWTFPQSQSLHSFRAHPTVVVCIQSRAEPHTLLTAGKEGIIKEWNLTSGDLLRHL 321
Cdd:COG2319 79 AAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 322 KLGEE-LYALQFIDNttffcqtthqfslrrlpgfyslfnicGSipqqlrrircgnnwyRILCATEDGLLRFVSPVTGDLL 400
Cdd:COG2319 159 TGHSGaVTSVAFSPD--------------------------GK---------------LLASGSDDGTVRLWDLATGKLL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 401 litWPFSVLDHAV-DWAYDPNKEELFVATGTSEVLVFDASRNPCpvkylLCTSPDIQDYVQCLAygnFHL-GRglegLMF 478
Cdd:COG2319 198 ---RTLTGHTGAVrSVAFSPDGKLLASGSADGTVRLWDLATGKL-----LRTLTGHSGSVRSVA---FSPdGR----LLA 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 479 SGHQSGMIRV--LSQHSCARIEKNvHFGAVLALSIfygglmtSRENSLLCSYGVDDYIQL-------SEAVLTGARLQLK 549
Cdd:COG2319 263 SGSADGTVRLwdLATGELLRTLTG-HSGGVNSVAF-------SPDGKLLASGSDDGTVRLwdlatgkLLRTLTGHTGAVR 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 550 TLAciLSscPLKHLVllpkAVGAITSTncLRLWKLrefisfgssQGIKFIETLPLHQCPITSfdVCLSLN--VFATGGSD 627
Cdd:COG2319 335 SVA--FS--PDGKTL----ASGSDDGT--VRLWDL---------ATGELLRTLTGHTGAVTS--VAFSPDgrTLASGSAD 393
|
410
....*....|
gi 2482565915 628 GTVRLWDFQG 637
Cdd:COG2319 394 GTVRLWDLAT 403
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1804-1985 |
3.69e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 59.54 E-value: 3.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1804 EAKNQELdgQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDrrPEEVK 1883
Cdd:COG4913 613 AALEAEL--AELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDAS--SDDLA 688
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1884 HLQERREKLREQKQRLAQEKERIAQRKTELkvkKTRLAQMEESLSQERHKL----SLEKERLTERGKALHDKEKKLLKGK 1959
Cdd:COG4913 689 ALEEQLEELEAELEELEEELDELKGEIGRL---EKELEQAEEELDELQDRLeaaeDLARLELRALLEERFAAALGDAVER 765
|
170 180
....*....|....*....|....*.
gi 2482565915 1960 EQLQDIKGKLETYREKLINLSKKLME 1985
Cdd:COG4913 766 ELRENLEERIDALRARLNRAEEELER 791
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1720-2065 |
3.95e-08 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 58.38 E-value: 3.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1720 IEMTLGEKETFLsqqEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEK 1799
Cdd:COG4372 4 LGEKVGKARLSL---FGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1800 KVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKeeemlalyeknLSLEEEMLAQEAKHQMEEEKRLALEKDRRP 1879
Cdd:COG4372 81 ELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEE-----------LQKERQDLEQQRKQLEAQIAELQSEIAERE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1880 EEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGK 1959
Cdd:COG4372 150 EELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEA 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1960 EQLQDIKGKLETYREklINLSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLI 2039
Cdd:COG4372 230 KLGLALSALLDALEL--EEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAAL 307
|
330 340
....*....|....*....|....*.
gi 2482565915 2040 REETEIIKEAEELTSEMKRVAREKME 2065
Cdd:COG4372 308 SLIGALEDALLAALLELAKKLELALA 333
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1679-1940 |
3.97e-08 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 59.37 E-value: 3.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1679 KKLLAHEEEKLAQEERRLAQEEGKLAH--EYVKSATKGGKLAHIEMTLgEKETFLSQQEEilsREAEFLAQKKKKLARKL 1756
Cdd:pfam17380 299 ERLRQEKEEKAREVERRRKLEEAEKARqaEMDRQAAIYAEQERMAMER-ERELERIRQEE---RKRELERIRQEEIAMEI 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1757 EKMAHEKEKIAKKINKVEEVKAVL-AQKTETMMEKEKNLASEEKKVREE---AKNQELDGQELALKEDELYEEAEKLedK 1832
Cdd:pfam17380 375 SRMRELERLQMERQQKNERVRQELeAARKVKILEEERQRKIQQQKVEMEqirAEQEEARQREVRRLEEERAREMERV--R 452
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1833 REALAKEEEMLALYEKnlslEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREK-LREQKQRLAQEKE------- 1904
Cdd:pfam17380 453 LEEQERQQQVERLRQQ----EEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAmIEEERKRKLLEKEmeerqka 528
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 2482565915 1905 -------RIA--QRKTELKV-KKTRLAQMEESLSQERHKL-SLEKER 1940
Cdd:pfam17380 529 iyeeerrREAeeERRKQQEMeERRRIQEQMRKATEERSRLeAMERER 575
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
412-674 |
5.51e-08 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 57.34 E-value: 5.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 412 AVDWAYDPNKeeLFVATGTSEVLVFDASRNPCpvKYLLCTSPDIQDYVQCLAYGNFhlgrgleglMFSGHQSGMIRVLSQ 491
Cdd:cd00200 14 CVAFSPDGKL--LATGSGDGTIKVWDLETGEL--LRTLKGHTGPVRDVAASADGTY---------LASGSSDKTIRLWDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 492 HSCARIEK-NVHFGAVLALSIfygglmtSRENSLLCSYGVDDYIQLSEaVLTGarLQLKTLACIlsSCPLKHLVLLP--K 568
Cdd:cd00200 81 ETGECVRTlTGHTSYVSSVAF-------SPDGRILSSSSRDKTIKVWD-VETG--KCLTTLRGH--TDWVNSVAFSPdgT 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 569 AVGAITSTNCLRLWKLREFisfgssqgiKFIETLPLHQCPITSFDVCLSLNVFATGGSDGTVRLWDFQ-GRLIAMLDSsl 647
Cdd:cd00200 149 FVASSSQDGTIKLWDLRTG---------KCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLStGKCLGTLRG-- 217
|
250 260
....*....|....*....|....*..
gi 2482565915 648 HFGPLCFandrgdllVTFNQSIYLVSC 674
Cdd:cd00200 218 HENGVNS--------VAFSPDGYLLAS 236
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1649-2255 |
1.87e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 57.29 E-value: 1.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1649 RKERRQIRMAQKQARADWRQARGERRRAREKKL--------LAHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHI 1720
Cdd:TIGR00618 247 QKREAQEEQLKKQQLLKQLRARIEELRAQEAVLeetqerinRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1721 EMtlgEKETFLSQQEEI--LSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAvLAQKTETMMEKEKNLASEE 1798
Cdd:TIGR00618 327 LM---KRAAHVKQQSSIeeQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHT-LQQQKTTLTQKLQSLCKEL 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1799 KKVREEAKNQE-LDGQELALKEDELYEEAE-KLEDKREAL---AKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLAL 1873
Cdd:TIGR00618 403 DILQREQATIDtRTSAFRDLQGQLAHAKKQqELQQRYAELcaaAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIH 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1874 EKDRR--PEEVKHLQERREKLREQKQRLAqEKERIAQRKTELKVKKTRL-------AQMEESLSQERHKLSLEKERLTER 1944
Cdd:TIGR00618 483 LQETRkkAVVLARLLELQEEPCPLCGSCI-HPNPARQDIDNPGPLTRRMqrgeqtyAQLETSEEDVYHQLTSERKQRASL 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1945 GKALHDKEKKLLKGKEQLQDIKGKLETYREKLINL----SKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAV 2020
Cdd:TIGR00618 562 KEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLqdltEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQEL 641
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2021 EKVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMKRVAREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRv 2100
Cdd:TIGR00618 642 ALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF- 720
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2101 siEEKILAYEDRLLATEEKDAARGHL--ELTREQR-ICAHEERKLAKATRKLDREKGVSKKPAESRKTLKVLINLI-SKV 2176
Cdd:TIGR00618 721 --NEIENASSSLGSDLAAREDALNQSlkELMHQARtVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLReEDT 798
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2177 RKVTQKESKM-TKMNRSLLIKEAE---LSMEEKRLDIKELEDTEEQPEIIMEERKLAKMERRLARQMRrlstEEKRMAEE 2252
Cdd:TIGR00618 799 HLLKTLEAEIgQEIPSDEDILNLQcetLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQ----EQAKIIQL 874
|
...
gi 2482565915 2253 EGQ 2255
Cdd:TIGR00618 875 SDK 877
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1749-2249 |
2.03e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 57.05 E-value: 2.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1749 KKKLARKLEKMAHEKEKIAKKINKVEEV---------KAVLAQKT---ETMMEKEK--NLASEEKKVREEAKNQ------ 1808
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELhekqkfylrQSVIDLQTklqEMQMERDAmaDIRRRESQSQEDLRNQlqntvh 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1809 ELDGQElALKEDELYEEAEKLEDKREALAKEEEMLALYeKNLSLEEEMLAQEAKHQMEEEKRL-------ALEKDRRP-- 1879
Cdd:pfam15921 153 ELEAAK-CLKEDMLEDSNTQIEQLRKMMLSHEGVLQEI-RSILVDFEEASGKKIYEHDSMSTMhfrslgsAISKILREld 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1880 EEVKHLQER-------REKLREQKQR-----LAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGK- 1946
Cdd:pfam15921 231 TEISYLKGRifpvedqLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARn 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1947 -------ALHDKEKKLLKGKEQLQDIKgklETYREKLINLSKKLMEEKTVFV-AKKEKLTVTEKKIEMEDML------LA 2012
Cdd:pfam15921 311 qnsmymrQLSDLESTVSQLRSELREAK---RMYEDKIEELEKQLVLANSELTeARTERDQFSQESGNLDDQLqklladLH 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2013 EKQGKLAVEKVKLAKEITEVIQNSQLI---REETEI----IKEAEELTSEMKRVAREKME-----LVGELEEPPKTEIKE 2080
Cdd:pfam15921 388 KREKELSLEKEQNKRLWDRDTGNSITIdhlRRELDDrnmeVQRLEALLKAMKSECQGQMErqmaaIQGKNESLEKVSSLT 467
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2081 AILRRRRLAMHEV--DLMKKRVSIEEKILAYEDRLLATEEKDAA-------------RGHLELTREQRIcAHEERKLAKA 2145
Cdd:pfam15921 468 AQLESTKEMLRKVveELTAKKMTLESSERTVSDLTASLQEKERAieatnaeitklrsRVDLKLQELQHL-KNEGDHLRNV 546
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2146 TRKLDrekGVSKKPAESRKTLKVLINlisKVRKVTQKESKMTKMNRSLLIKEAELSME--EKRLDIKELEdteeqpeiIM 2223
Cdd:pfam15921 547 QTECE---ALKLQMAEKDKVIEILRQ---QIENMTQLVGQHGRTAGAMQVEKAQLEKEinDRRLELQEFK--------IL 612
|
570 580
....*....|....*....|....*.
gi 2482565915 2224 EERKLAKMeRRLARQMRRLSTEEKRM 2249
Cdd:pfam15921 613 KDKKDAKI-RELEARVSDLELEKVKL 637
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1686-1909 |
2.07e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.93 E-value: 2.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1686 EEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEK 1765
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1766 IAK------KINKVEEVKAVLAQKtetmmekeknlaSEEKKVREEAKNQELdGQELALKEDELYEEAEKLEDKREALAKE 1839
Cdd:COG4942 106 LAEllralyRLGRQPPLALLLSPE------------DFLDAVRRLQYLKYL-APARREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1840 EEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQR 1909
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1683-2262 |
2.47e-07 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 56.77 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1683 AHEEEKLAQEERRLAQEEGKLAHeyvksaTKGGKLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHE 1762
Cdd:pfam12128 240 RPEFTKLQQEFNTLESAELRLSH------LHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAA 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1763 KEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQEldgQELALKEDELYEEAEKLeDKREALAKEEEM 1842
Cdd:pfam12128 314 DAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLE---ERLKALTGKHQDVTAKY-NRRRSKIKEQNN 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1843 LALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQ------RKTELKVK 1916
Cdd:pfam12128 390 RDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQatatpeLLLQLENF 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1917 KTRLAQMEESLSQERHK-LSLEKERLTERGKAlHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLM----------E 1985
Cdd:pfam12128 470 DERIERAREEQEAANAEvERLQSELRQARKRR-DQASEALRQASRRLEERQSALDELELQLFPQAGTLLhflrkeapdwE 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1986 EKTVFVAKKEKLTVTEKKIEMEDmllAEKQGKLAVEKVKL---AKEITEVIQNSQLIREETEIIKEAeeLTSEMKRVARE 2062
Cdd:pfam12128 549 QSIGKVISPELLHRTDLDPEVWD---GSVGGELNLYGVKLdlkRIDVPEWAASEEELRERLDKAEEA--LQSAREKQAAA 623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2063 KMELV---GELEEPPKTE------IKEAILRRRRLA-MHEVDLMKKRVSIEEKILAYEDRL--LATEEKDAARGHLELTR 2130
Cdd:pfam12128 624 EEQLVqanGELEKASREEtfartaLKNARLDLRRLFdEKQSEKDKKNKALAERKDSANERLnsLEAQLKQLDKKHQAWLE 703
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2131 EQRICAHEERKLAKATRKldrekgvskkpaESRKTLKVLINLISkvrkvTQKESKMTKMNRSLLIKEAELSMEEKRLDIk 2210
Cdd:pfam12128 704 EQKEQKREARTEKQAYWQ------------VVEGALDAQLALLK-----AAIAARRSGAKAELKALETWYKRDLASLGV- 765
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 2482565915 2211 eledteeqpeiimEERKLAKMERRLARQMRRLSTEEKRMAEEEGQFDWESKQ 2262
Cdd:pfam12128 766 -------------DPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQET 804
|
|
| TolA |
COG3064 |
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis]; |
1753-2118 |
2.65e-07 |
|
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 56.20 E-value: 2.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1753 ARKLEKMAHEKEKIAKKINKVEEVKAVLAQKtetmmEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDK 1832
Cdd:COG3064 1 AQEALEEKAAEAAAQERLEQAEAEKRAAAEA-----EQKAKEEAEEERLAELEAKRQAEEEAREAKAEAEQRAAELAAEA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1833 REALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTE 1912
Cdd:COG3064 76 AKKLAEAEKAAAEAEKKAAAEKAKAAKEAEAAAAAEKAAAAAEKEKAEEAKRKAEEEAKRKAEEERKAAEAEAAAKAEAE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1913 LKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLMEEKTVFVA 1992
Cdd:COG3064 156 AARAAAAAAAAAAAAAARAAAGAAAALVAAAAAAVEAADTAAAAAAALAAAAAAAAADAALLALAVAARAAAASREAALA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1993 KKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMKRVAREKMELVGELEE 2072
Cdd:COG3064 236 AVEATEEAALGGAEEAADLAAVGVLGAALAAAAAGAAALSSGLVVVAAALAGLAAAAAGLVLDDSAALAAELLGAVAAEE 315
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 2482565915 2073 PPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRLLATEE 2118
Cdd:COG3064 316 AVLAAAAAAGALVVRGGGAASLEAALSLLAAGAAAAAAGAGALATG 361
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1720-2252 |
8.67e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 55.12 E-value: 8.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1720 IEMT-LGEKETFLSQQEEILSREAEFLA-QKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMmEKEKNLA-S 1796
Cdd:pfam15921 278 VEITgLTEKASSARSQANSIQSQLEIIQeQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEEL-EKQLVLAnS 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1797 EEKKVREEAK--NQE---LDGQ------ELALKEDELYEEAEKLE-----DKREALAKEEEMLALYEKNLSLEE-----E 1855
Cdd:pfam15921 357 ELTEARTERDqfSQEsgnLDDQlqkllaDLHKREKELSLEKEQNKrlwdrDTGNSITIDHLRRELDDRNMEVQRleallK 436
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1856 MLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQekeriaqrktELKVKKTRLAQMEESLSQERHKLS 1935
Cdd:pfam15921 437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVE----------ELTAKKMTLESSERTVSDLTASLQ 506
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1936 lEKERLTERGKAlhDKEKKLLKGKEQLQDIKgKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAE-- 2013
Cdd:pfam15921 507 -EKERAIEATNA--EITKLRSRVDLKLQELQ-HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQhg 582
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2014 -KQGKLAVEKVKLAKEITEviqnSQLIREETEIIKEAE-----ELTSEMKRVAREKMELVGELEEPpkteikeaiLRRRR 2087
Cdd:pfam15921 583 rTAGAMQVEKAQLEKEIND----RRLELQEFKILKDKKdakirELEARVSDLELEKVKLVNAGSER---------LRAVK 649
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2088 lamhevDLMKKRvsieekilayeDRLLatEEKDAARGHL-ELTRE----QRICAHEERKLAKATRKLDRE-KGVSKKPAE 2161
Cdd:pfam15921 650 ------DIKQER-----------DQLL--NEVKTSRNELnSLSEDyevlKRNFRNKSEEMETTTNKLKMQlKSAQSELEQ 710
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2162 SRKTLKVLIN--------LISKVRKVTQKESKMTKMNRSL-LIKEAELSMEEKRLDIKeledtEEQPEIIMEERKLAKME 2232
Cdd:pfam15921 711 TRNTLKSMEGsdghamkvAMGMQKQITAKRGQIDALQSKIqFLEEAMTNANKEKHFLK-----EEKNKLSQELSTVATEK 785
|
570 580
....*....|....*....|
gi 2482565915 2233 RRLARQMRRLSTEEKRMAEE 2252
Cdd:pfam15921 786 NKMAGELEVLRSQERRLKEK 805
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1821-1986 |
8.95e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.92 E-value: 8.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1821 ELYEEAEKLEDKREALAKEEEMLALYEKNLSLEeemLAQEAKHQMEEEK-RLALEKDRRPEEVKHLQERREKLREQK--- 1896
Cdd:COG4913 259 ELAERYAAARERLAELEYLRAALRLWFAQRRLE---LLEAELEELRAELaRLEAELERLEARLDALREELDELEAQIrgn 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1897 --QRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLETYRE 1974
Cdd:COG4913 336 ggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALR 415
|
170
....*....|..
gi 2482565915 1975 KLINLSKKLMEE 1986
Cdd:COG4913 416 DLRRELRELEAE 427
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
1731-2024 |
9.39e-07 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 53.38 E-value: 9.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1731 LSQQEEILSREAEFLAQKKKKLARKLEKMAHEK-EKIAKKINKVEEVKAVLAQKTEtMMEKEKNLASEEKKVREEAKnqe 1809
Cdd:COG1340 13 LEEKIEELREEIEELKEKRDELNEELKELAEKRdELNAQVKELREEAQELREKRDE-LNEKVKELKEERDELNEKLN--- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1810 ldgqELALKEDELYEEAEKLEDKREALAKEEEMLAlyeknlSLEEEMlaQEAKHQMEEEKRLAL---EKDRRPEEVKHLQ 1886
Cdd:COG1340 89 ----ELREELDELRKELAELNKAGGSIDKLRKEIE------RLEWRQ--QTEVLSPEEEKELVEkikELEKELEKAKKAL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1887 ERREKLREQKQRLAQEKERIAqrktELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHdkekkllkgkEQLQDIK 1966
Cdd:COG1340 157 EKNEKLKELRAELKELRKEAE----EIHKKIKELAEEAQELHEEMIELYKEADELRKEADELH----------KEIVEAQ 222
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2482565915 1967 GKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMllaEKQGKLAVEKVK 2024
Cdd:COG1340 223 EKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEEL---EEKAEEIFEKLK 277
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1859-2034 |
1.16e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 54.01 E-value: 1.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1859 QEAKHQMEEEKRLAlekdrrpEEVKHLQERREKLREQKQRLAQEKErIAQRKTELKVKKTRLAQMEESLSQERHKLSLEK 1938
Cdd:PRK12704 38 EEAKRILEEAKKEA-------EAIKKEALLEAKEEIHKLRNEFEKE-LRERRNELQKLEKRLLQKEENLDRKLELLEKRE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1939 ERLTERGKALhdkEKKLLKGKEQLQDIKGKLETYREKLINLSKKLMEEktvfvAKKEKLTVTEKKIEMEDMLL---AEKQ 2015
Cdd:PRK12704 110 EELEKKEKEL---EQKQQELEKKEEELEELIEEQLQELERISGLTAEE-----AKEILLEKVEEEARHEAAVLikeIEEE 181
|
170 180
....*....|....*....|
gi 2482565915 2016 GKLAVEkvKLAKEI-TEVIQ 2034
Cdd:PRK12704 182 AKEEAD--KKAKEIlAQAIQ 199
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
1788-1949 |
1.16e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 54.33 E-value: 1.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1788 MEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEEEmlalyeknLSLEEEMLAQEAKHQMEE 1867
Cdd:PRK12705 25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREE--------LQREEERLVQKEEQLDAR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1868 EKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRkTELKVKKTRLAQMEESLSQE---RHKLSLEKERLTER 1944
Cdd:PRK12705 97 AEKLDNLENQLEEREKALSARELELEELEKQLDNELYRVAGL-TPEQARKLLLKLLDAELEEEkaqRVKKIEEEADLEAE 175
|
....*
gi 2482565915 1945 GKALH 1949
Cdd:PRK12705 176 RKAQN 180
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1679-1943 |
1.34e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 54.46 E-value: 1.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1679 KKLLAHEEEKLAQEERRLAQEEGKLAHeyvksatkggklAHIEMTLGekETFLSQQEEILSReaefLAQKKKKLARKLEK 1758
Cdd:pfam12128 610 EEALQSAREKQAAAEEQLVQANGELEK------------ASREETFA--RTALKNARLDLRR----LFDEKQSEKDKKNK 671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1759 -MAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKnQELDGqELALKEDELYEEAEKLEDKREALA 1837
Cdd:pfam12128 672 aLAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYW-QVVEG-ALDAQLALLKAAIAARRSGAKAEL 749
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1838 KE-EEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVK 1916
Cdd:pfam12128 750 KAlETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQ 829
|
250 260 270
....*....|....*....|....*....|.
gi 2482565915 1917 KTRLAQMEE----SLSQERHKLSLEKERLTE 1943
Cdd:pfam12128 830 LARLIADTKlrraKLEMERKASEKQQVRLSE 860
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1736-1902 |
1.37e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 52.23 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1736 EILSREAEfLAQKKKKLARKLEKMaheKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVreeAKNQELDGQEL 1815
Cdd:COG1579 14 ELDSELDR-LEHRLKELPAELAEL---EDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI---KKYEEQLGNVR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1816 ALKE-DELYEEAEKLEDKREALakEEEMLALYEKNLSLEEEMLAQEAKHQmEEEKRLALEKDRRPEEVKHLQERREKLRE 1894
Cdd:COG1579 87 NNKEyEALQKEIESLKRRISDL--EDEILELMERIEELEEELAELEAELA-ELEAELEEKKAELDEELAELEAELEELEA 163
|
....*...
gi 2482565915 1895 QKQRLAQE 1902
Cdd:COG1579 164 EREELAAK 171
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1755-2446 |
1.37e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 54.30 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1755 KLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKRE 1834
Cdd:PRK03918 159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1835 ALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLAL--EKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTE 1912
Cdd:PRK03918 239 EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEEleEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1913 LKvkkTRLAQMEESLSqERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGK---LETYREKLINLSKKLMEEKtV 1989
Cdd:PRK03918 319 LE---EEINGIEERIK-ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKkeeLERLKKRLTGLTPEKLEKE-L 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1990 FVAKKEKLTVTEKKIEMEDMLLA----EKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIkeaEELTSEMKRVAREKME 2065
Cdd:PRK03918 394 EELEKAKEEIEEEISKITARIGElkkeIKELKKAIEELKKAKGKCPVCGRELTEEHRKELL---EEYTAELKRIEKELKE 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2066 LVGELEEppkteikeaiLRRRRLAMHEVDLMKKRVSIEEKILayeDRLLATEEKDAARGHLELTREQRicahEERKLAKA 2145
Cdd:PRK03918 471 IEEKERK----------LRKELRELEKVLKKESELIKLKELA---EQLKELEEKLKKYNLEELEKKAE----EYEKLKEK 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2146 TRKLDREKGVSKKPAESRKTL-KVLINLISKVRKVTQKESKMTKMNRSLLIKeaelSMEEKRLDIKELEDT-EEQPEIIM 2223
Cdd:PRK03918 534 LIKLKGEIKSLKKELEKLEELkKKLAELEKKLDELEEELAELLKELEELGFE----SVEELEERLKELEPFyNEYLELKD 609
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2224 EERKLAKMERRLARQMRRLSTEEKRMAEEEGQFDWESKQdseeeveeeeveeeevgeekveeeevgeeeedletekgalf 2303
Cdd:PRK03918 610 AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE----------------------------------------- 648
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2304 fkrlrirrkgfmeiLPGMEKFYNLlEQVGHKENFFQDMESLL--VEVDKESLsEGEREEAEKDTEaeveeeegeekeeeg 2381
Cdd:PRK03918 649 --------------LEELEKKYSE-EEYEELREEYLELSRELagLRAELEEL-EKRREEIKKTLE--------------- 697
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2482565915 2382 eekeeegeegekkeeegkkeekgkkegekkeeeekkegekkeeEWKEEkeqveGEEREKKGKEIE 2446
Cdd:PRK03918 698 -------------------------------------------KLKEE-----LEEREKAKKELE 714
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1731-1936 |
1.39e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 53.61 E-value: 1.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1731 LSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREE------ 1804
Cdd:COG4942 32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEElaellr 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1805 --AKNQELDGQELALKEDELYEEA----------EKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLA 1872
Cdd:COG4942 112 alYRLGRQPPLALLLSPEDFLDAVrrlqylkylaPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALE 191
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 1873 LEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSL 1936
Cdd:COG4942 192 ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
242-531 |
1.45e-06 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 52.72 E-value: 1.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 242 SPITCCFTSLEENLLYAGNKVGEVYVWTFPQSQSLHSFRAHPTVVVCIQSRAEPHTLLTAGKEGIIKEWNLTSGDLLRHL 321
Cdd:cd00200 10 GGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 322 KlG--EELYALQFIDNTTFFCQTTHQFSLRrlpgfysLFNIcgSIPQQLRRIRCGNNWYRILCATEDGllRFVSPVTGDL 399
Cdd:cd00200 90 T-GhtSYVSSVAFSPDGRILSSSSRDKTIK-------VWDV--ETGKCLTTLRGHTDWVNSVAFSPDG--TFVASSSQDG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 400 LLITW------PFSVLDHAVDW----AYDPNKEELFVATGTSEVLVFDASRNPCpvkylLCTSPDIQDYVQCLAygnFHL 469
Cdd:cd00200 158 TIKLWdlrtgkCVATLTGHTGEvnsvAFSPDGEKLLSSSSDGTIKLWDLSTGKC-----LGTLRGHENGVNSVA---FSP 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2482565915 470 GRgleGLMFSGHQSGMIRV---LSQHSCARIEKnvHFGAVLALSIfygglmtSRENSLLCSYGVD 531
Cdd:cd00200 230 DG---YLLASGSEDGTIRVwdlRTGECVQTLSG--HTNSVTSLAW-------SPDGKRLASGSAD 282
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1762-1947 |
1.61e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 53.30 E-value: 1.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1762 EKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQEldgQELALKEDELYEEAEKLEDKREALAKEee 1841
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQ---AEIDKLQAEIAEAEAEIEERREELGER-- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1842 MLALYEK--NLSLEEEML----AQEAKHQMEEEKRLAlEKDRrpEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKV 1915
Cdd:COG3883 92 ARALYRSggSVSYLDVLLgsesFSDFLDRLSALSKIA-DADA--DLLEELKADKAELEAKKAELEAKLAELEALKAELEA 168
|
170 180 190
....*....|....*....|....*....|....*....
gi 2482565915 1916 KKTRL-AQMEE------SLSQERHKLSLEKERLTERGKA 1947
Cdd:COG3883 169 AKAELeAQQAEqeallaQLSAEEAAAEAQLAELEAELAA 207
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1686-1942 |
1.92e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 53.82 E-value: 1.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1686 EEKLAQEERRLAQEEGKLAHEYVKSATKGGKlaHIEMTLGEKETFLSQQEEilsREAEFLAQKKKKLARKLEKMAHEKEK 1765
Cdd:TIGR00618 638 SQELALKLTALHALQLTLTQERVREHALSIR--VLPKELLASRQLALQKMQ---SEKEQLTYWKEMLAQCQTLLRELETH 712
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1766 IAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEA----KNQELDGQELALKE-------DELYEEAEKLEDKRE 1834
Cdd:TIGR00618 713 IEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQArtvlKARTEAHFNNNEEVtaalqtgAELSHLAAEIQFFNR 792
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1835 ALAKEEEMLALYEKNL-----SLEEEMLAQEAKHQMEEEKRLAL--EKDRRPEEVKHLQERREKLREQKQRLAQEKERIA 1907
Cdd:TIGR00618 793 LREEDTHLLKTLEAEIgqeipSDEDILNLQCETLVQEEEQFLSRleEKSATLGEITHQLLKYEECSKQLAQLTQEQAKII 872
|
250 260 270
....*....|....*....|....*....|....*.
gi 2482565915 1908 QRKTELKVKKTRLAQMEE-SLSQERHKLSLEKERLT 1942
Cdd:TIGR00618 873 QLSDKLNGINQIKIQFDGdALIKFLHEITLYANVRL 908
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1679-2057 |
1.99e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 53.57 E-value: 1.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1679 KKLLAhEEEKLAQEER---RLAQEEGKLAHEYVKSATKGGKLAH-----IEMTLGEKETFLSQQEEI------------- 1737
Cdd:pfam05483 411 KKILA-EDEKLLDEKKqfeKIAEELKGKEQELIFLLQAREKEIHdleiqLTAIKTSEEHYLKEVEDLktelekeklknie 489
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1738 LSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQeldGQELAL 1817
Cdd:pfam05483 490 LTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQK---GDEVKC 566
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1818 KEDELYEEAEKLEdkREALAKEEEMLALYEKNLSLEEEMlaqEAKHQMEEEKRlalekdrrpEEVKHLQERREKlrEQKQ 1897
Cdd:pfam05483 567 KLDKSEENARSIE--YEVLKKEKQMKILENKCNNLKKQI---ENKNKNIEELH---------QENKALKKKGSA--ENKQ 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1898 RLAQEKeRIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERL---TERGKALHDKEKKLLkgkeqlQDIKGKLETYRE 1974
Cdd:pfam05483 631 LNAYEI-KVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLleeVEKAKAIADEAVKLQ------KEIDKRCQHKIA 703
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1975 KLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMEDmllAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIK-EAEELT 2053
Cdd:pfam05483 704 EMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQ---SSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKmEAKENT 780
|
....
gi 2482565915 2054 SEMK 2057
Cdd:pfam05483 781 AILK 784
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1724-1835 |
2.04e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 53.24 E-value: 2.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1724 LGEKETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEvkavLAQKTETMMEKEKNLASEE----- 1798
Cdd:PRK12704 84 LQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEE----LIEEQLQELERISGLTAEEakeil 159
|
90 100 110
....*....|....*....|....*....|....*...
gi 2482565915 1799 -KKVREEAKnqeldgQELALKEDELYEEAeKLEDKREA 1835
Cdd:PRK12704 160 lEKVEEEAR------HEAAVLIKEIEEEA-KEEADKKA 190
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1817-2677 |
2.33e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 53.82 E-value: 2.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1817 LKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRL---ALEKDRRPEEVKHLQERREKLR 1893
Cdd:pfam02463 156 LEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALeyyQLKEKLELEEEYLLYLDYLKLN 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1894 EQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKAlhdkekkllkgkeQLQDIKGKLETYR 1973
Cdd:pfam02463 236 EERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELK-------------LLAKEEEELKSEL 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1974 EKLINLSKKLMEEKTVFVAKKEKLtvtEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQL----IREETEIIKEA 2049
Cdd:pfam02463 303 LKLERRKVDDEEKLKESEKEKKKA---EKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLqeklEQLEEELLAKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2050 EELTSEMKRVAREKmELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKIlayedrllaTEEKDAARGHLElt 2129
Cdd:pfam02463 380 KLESERLSSAAKLK-EEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEE---------EESIELKQGKLT-- 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2130 reqrICAHEERKLAKATRKLDREKGVSKKPAESRKTLKVLINLISKVRKVTQKESKMT-KMNRSLLIKEAELSMEEKRLD 2208
Cdd:pfam02463 448 ----EEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKeSKARSGLKVLLALIKDGVGGR 523
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2209 IKELEDTEEQPEIIMEERKLAKMERRLARQMRRLSTEEKRmaEEEGQFDWESKQDseEEVEEEEVEEEEVGEEKVEEEEV 2288
Cdd:pfam02463 524 IISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER--QKLVRALTELPLG--ARKLRLLIPKLKLPLKSIAVLEI 599
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2289 GEEEEDLETEKGALFFKRLRIRRKGFMEILPGMEKFYNLLEQVGHKENFFQDMESLLVEVDKESLSEGEREEAEKDTEAE 2368
Cdd:pfam02463 600 DPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2369 VEEEEGEEKEEEGEEKEEEGEEGEKKEEEGKKEEKGKKEGEKKEEEEKKEGEKKEEEWKEEKEQVEGEEREKKGKEIEEW 2448
Cdd:pfam02463 680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2449 KREKEMEEIEKKEKEKEREAGWEEEEEE----------GEEEEEEEEQKEEKEQVEGEEREKKGEEKGEEKGEEKGEEKG 2518
Cdd:pfam02463 760 EEKEEEKSELSLKEKELAEEREKTEKLKveeekeeklkAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELA 839
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2519 EEEIEKEEKKMEKKVHEEEEEKEEEKKEEEIEESSSEEEVKSVGHIEEEEEKHLWEEERKEEAVLKREKPKIQVERKKVI 2598
Cdd:pfam02463 840 LELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEI 919
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2482565915 2599 QRRAMLPQEIPVLKGSAMRLSSPLGKLVPFPEGMEPEEKQISGEEEARVFKIPTMTPMISLRAKVMDKERELLDKSKLE 2677
Cdd:pfam02463 920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
1733-1904 |
2.57e-06 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 52.50 E-value: 2.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1733 QQEEILSREAEFL-AQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTEtmmekEKNLASEEKKVREEAKNQELD 1811
Cdd:PRK09510 99 EQERLKQLEKERLaAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAKAKAEAE-----AKRAAAAAKKAAAEAKKKAEA 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1812 GQELALKEDELYEEAEKLEDKREALAKeeemlalyEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREK 1891
Cdd:PRK09510 174 EAAKKAAAEAKKKAEAEAAAKAAAEAK--------KKAEAEAKKKAAAEAKKKAAAEAKAAAAKAAAEAKAAAEKAAAAK 245
|
170
....*....|...
gi 2482565915 1892 LREQKQRLAQEKE 1904
Cdd:PRK09510 246 AAEKAAAAKAAAE 258
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
152-322 |
2.77e-06 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 52.61 E-value: 2.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 152 ISCLCFNPETKMLLSGILGGVVT-WNIeQTGKGLRMLQispiSGDEVVQNIALNgPNGCILALCES--TLRVLEHQGqGQ 228
Cdd:COG2319 207 VRSVAFSPDGKLLASGSADGTVRlWDL-ATGKLLRTLT----GHSGSVRSVAFS-PDGRLLASGSAdgTVRLWDLAT-GE 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 229 LeeskRFVATNCCSPITCCFTSLEENLLYAGNKVGEVYVWTFPQSQSLHSFRAHPTVVVCIQSRAEPHTLLTAGKEGIIK 308
Cdd:COG2319 280 L----LRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVR 355
|
170
....*....|....
gi 2482565915 309 EWNLTSGDLLRHLK 322
Cdd:COG2319 356 LWDLATGELLRTLT 369
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
597-634 |
3.42e-06 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 46.15 E-value: 3.42e-06
10 20 30
....*....|....*....|....*....|....*...
gi 2482565915 597 KFIETLPLHQCPITSFDVCLSLNVFATGGSDGTVRLWD 634
Cdd:smart00320 3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
1746-2063 |
6.06e-06 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 51.07 E-value: 6.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1746 AQKKKKLARKLEKMAHEKEKiakkinkveevkavlaqktETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEE 1825
Cdd:pfam13868 26 AQIAEKKRIKAEEKEEERRL-------------------DEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEERE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1826 AEKLEDKREALAKEEEMLALYEKNLslEEEMLAQEAKHQMEEEKRlalekdrrpEEVKHLQERREKLREQKQRLAQEKER 1905
Cdd:pfam13868 87 QKRQEEYEEKLQEREQMDEIVERIQ--EEDQAEAEEKLEKQRQLR---------EEIDEFNEEQAEWKELEKEEEREEDE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1906 IAQRKTELKvkktrlAQMEESLSQERHKLSLEKERLTERgkalhdkekkllkGKEQLQDIKGKLETyREKLINlsKKLME 1985
Cdd:pfam13868 156 RILEYLKEK------AEREEEREAEREEIEEEKEREIAR-------------LRAQQEKAQDEKAE-RDELRA--KLYQE 213
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2482565915 1986 EKTVFVAKKEKLTVtEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMKRVAREK 2063
Cdd:pfam13868 214 EQERKERQKEREEA-EKKARQRQELQQAREEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLE 290
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
1870-2004 |
7.13e-06 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 52.01 E-value: 7.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1870 RLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKteLKVKKTRLAQMEESLSQERHKLSLEKERLTErgkalh 1949
Cdd:COG0542 401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFER--LAELRDELAELEEELEALKARWEAEKELIEE------ 472
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2482565915 1950 dkekkllkgkeqLQDIKGKLETYREKLINLSKKL--MEEKTVFVAKKEKLTVTEKKI 2004
Cdd:COG0542 473 ------------IQELKEELEQRYGKIPELEKELaeLEEELAELAPLLREEVTEEDI 517
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1745-1947 |
7.58e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 50.98 E-value: 7.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1745 LAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVreEAKNQELDGQELALKED--EL 1822
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEI--AEAEAEIEERREELGERarAL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1823 YE------------EAEKLEDkreALAKEEEMLALYEKNLSLEEEmlAQEAKHQMEEEKrlalekdrrpeevKHLQERRE 1890
Cdd:COG3883 96 YRsggsvsyldvllGSESFSD---FLDRLSALSKIADADADLLEE--LKADKAELEAKK-------------AELEAKLA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2482565915 1891 KLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKA 1947
Cdd:COG3883 158 ELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1794-1944 |
7.60e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.92 E-value: 7.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1794 LASEEKKVREEAKNQEldgQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQ-----EAKHQMEEE 1868
Cdd:COG1579 22 LEHRLKELPAELAELE---DELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrnnkEYEALQKEI 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2482565915 1869 KRLALEKDRRPEEVKHLQERREKLREQkqrLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTER 1944
Cdd:COG1579 99 ESLKRRISDLEDEILELMERIEELEEE---LAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
1748-2221 |
7.92e-06 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 52.00 E-value: 7.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1748 KKKKLARKLEKMAhEKEKIAKKINKVE--EVKAVLAQK--------TETMMEKEKNLASEEKKVREEAKNQELDGQELAL 1817
Cdd:COG5022 814 SYLACIIKLQKTI-KREKKLRETEEVEfsLKAEVLIQKfgrslkakKRFSLLKKETIYLQSAQRVELAERQLQELKIDVK 892
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1818 KEDELYEEAEKLEDKREALAKEEEMLALyeKNLSLEEEMLAQEAKHQMEEEKRLALEKDrrpeevKHLQERREKLREQKQ 1897
Cdd:COG5022 893 SISSLKLVNLELESEIIELKKSLSSDLI--ENLEFKTELIARLKKLLNNIDLEEGPSIE------YVKLPELNKLHEVES 964
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1898 RL---AQEKERIAQRKTELKV-KKTRLAQMeESLSQERHKLSLEKERLTERGKALHDKEKK----------------LLK 1957
Cdd:COG5022 965 KLketSEEYEDLLKKSTILVReGNKANSEL-KNFKKELAELSKQYGALQESTKQLKELPVEvaelqsaskiissestELS 1043
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1958 GKEQLQDIKGKLE--------------TYREKLINLSKKLMEEKTVFVAKKeklTVTEKKIEMEDMLLAEKQGKL----- 2018
Cdd:COG5022 1044 ILKPLQKLKGLLLlennqlqarykalkLRRENSLLDDKQLYQLESTENLLK---TINVKDLEVTNRNLVKPANVLqfiva 1120
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2019 AVEKVKLAKEITEVI-QNSQLIREETEIIKEAEELTSEMKRVAREKMELVGE--LEEPPKTEIKEAILRRRRLAMHEVDL 2095
Cdd:COG5022 1121 QMIKLNLLQEISKFLsQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPpfAALSEKRLYQSALYDEKSKLSSSEVN 1200
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2096 MKKRVSIEEKILAYEDRLLATEEKDAAR----GHLELTREQRICAHEERKLAKATRKLDREKGVSKKPAESRKTLKVLIN 2171
Cdd:COG5022 1201 DLKNELIALFSKIFSGWPRGDKLKKLISegwvPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEE 1280
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 2482565915 2172 LISKVRKVTQKESKMTKMNrSLLIKEAELSME---EKRLDIKELEDTEEQPEI 2221
Cdd:COG5022 1281 VLPATINSLLQYINVGLFN-ALRTKASSLRWKsatEVNYNSEELDDWCREFEI 1332
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1679-2251 |
8.65e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 51.76 E-value: 8.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1679 KKLLAHEEEKLAQEERRLAQEEGKLAHEyvKSATKGG---KLAHIEMTLGEKETFLSQQEEILSREAEFLAQkkkkLARK 1755
Cdd:pfam12128 282 QETSAELNQLLRTLDDQWKEKRDELNGE--LSAADAAvakDRSELEALEDQHGAFLDADIETAAADQEQLPS----WQSE 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1756 LEKMAHEKEKIAKKINKVEE------VKAVLAQKTETMMEKEKNLASEEKKVRE-EAKNQELDGQELALKED------EL 1822
Cdd:pfam12128 356 LENLEERLKALTGKHQDVTAkynrrrSKIKEQNNRDIAGIKDKLAKIREARDRQlAVAEDDLQALESELREQleagklEF 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1823 YEEAEKLEDKRE--------ALAKEEEMLALYEKNLSLEEEMLAQEA--KHQMEEEKRLALEKDRRPEEVKHLQERREKL 1892
Cdd:pfam12128 436 NEEEYRLKSRLGelklrlnqATATPELLLQLENFDERIERAREEQEAanAEVERLQSELRQARKRRDQASEALRQASRRL 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1893 REQKQRLAQEKER-IAQRKTELKVKKTRLAQMEESL-----SQERHKLSLEKERLTERGK-ALHDKEKKLLKGKEQLQDI 1965
Cdd:pfam12128 516 EERQSALDELELQlFPQAGTLLHFLRKEAPDWEQSIgkvisPELLHRTDLDPEVWDGSVGgELNLYGVKLDLKRIDVPEW 595
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1966 KGKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIE-----MEDMLLA-----EKQGKLAVEKVKLAKEITEVIqn 2035
Cdd:pfam12128 596 AASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEkasreETFARTAlknarLDLRRLFDEKQSEKDKKNKAL-- 673
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2036 sqlireeTEIIKEAEEltsEMKRVAREKMELVGELEeppktEIKEAIlrRRRLAMHEVDLMKKRVSIEEKILAYEDRLla 2115
Cdd:pfam12128 674 -------AERKDSANE---RLNSLEAQLKQLDKKHQ-----AWLEEQ--KEQKREARTEKQAYWQVVEGALDAQLALL-- 734
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2116 TEEKDAARGHLEltREQRICaHEERKLAKATRKLDREKgVSKKPAEsRKTLKVLINLISKVR-KVTQKESKMT------K 2188
Cdd:pfam12128 735 KAAIAARRSGAK--AELKAL-ETWYKRDLASLGVDPDV-IAKLKRE-IRTLERKIERIAVRRqEVLRYFDWYQetwlqrR 809
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2482565915 2189 MNRSLLIKEAELSMEEKRLDIKEL-EDTEEQPEIIMEERK-LAKMERRLARQMRRLSTEEKRMAE 2251
Cdd:pfam12128 810 PRLATQLSNIERAISELQQQLARLiADTKLRRAKLEMERKaSEKQQVRLSENLRGLRCEMSKLAT 874
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1733-2065 |
9.36e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 51.71 E-value: 9.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1733 QQEEILSREAEFlaQKKKKLARKLEKMAHEkekIAKKINKVEEVKAVLAQKTETmmEKEKNLASEEKKVREEAKNQELD- 1811
Cdd:pfam01576 3 QEEEMQAKEEEL--QKVKERQQKAESELKE---LEKKHQQLCEEKNALQEQLQA--ETELCAEAEEMRARLAARKQELEe 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1812 ---GQELALKEDE-------------------LYEEAEKLEDKREAL--------AK----EEEMLALYEKNLSLE---- 1853
Cdd:pfam01576 76 ilhELESRLEEEEersqqlqnekkkmqqhiqdLEEQLDEEEAARQKLqlekvtteAKikklEEDILLLEDQNSKLSkerk 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1854 --EEMLAQEAKHQMEEE---KRLALEKDRRPEEVKHLQERREKlrEQKQRLAQEK-------------ERIAQRKTELKV 1915
Cdd:pfam01576 156 llEERISEFTSNLAEEEekaKSLSKLKNKHEAMISDLEERLKK--EEKGRQELEKakrklegestdlqEQIAELQAQIAE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1916 KKTRLAQMEESLSQ----------------------ERHKLSLEKERLTERG------KALHDKEKKLLKGKEQLQD--- 1964
Cdd:pfam01576 234 LRAQLAKKEEELQAalarleeetaqknnalkkirelEAQISELQEDLESERAarnkaeKQRRDLGEELEALKTELEDtld 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1965 ---IKGKLETYREK-LINLSKKLMEEKTVFVAKKEKLTV--TEKKIEMEDMLLAEKQGKLAVEKVKLAKEiteviqnsql 2038
Cdd:pfam01576 314 ttaAQQELRSKREQeVTELKKALEEETRSHEAQLQEMRQkhTQALEELTEQLEQAKRNKANLEKAKQALE---------- 383
|
410 420
....*....|....*....|....*..
gi 2482565915 2039 ireeteiiKEAEELTSEMKRVAREKME 2065
Cdd:pfam01576 384 --------SENAELQAELRTLQQAKQD 402
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1860-2253 |
1.18e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 51.19 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1860 EAKHQMEEEKRL-ALEKDRRP--EEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQErhklsl 1936
Cdd:PRK02224 197 EEKEEKDLHERLnGLESELAEldEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAET------ 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1937 EKERltergkalhdkekkllkgkeqlQDIKGKLETYREKLINLSkklmEEKTVFVAKKEkltVTEKKIEMedmlLAEKQG 2016
Cdd:PRK02224 271 ERER----------------------EELAEEVRDLRERLEELE----EERDDLLAEAG---LDDADAEA----VEARRE 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2017 KLAVEKVKLAKEITEVIQNSQLIREETEIIKE-AEELTSEMKRVAREKMELVGELEEppkteiKEAILRRRRLAMHEVDl 2095
Cdd:PRK02224 318 ELEDRDEELRDRLEECRVAAQAHNEEAESLREdADDLEERAEELREEAAELESELEE------AREAVEDRREEIEELE- 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2096 mkkrVSIEEKILAYEDrllATEEKDAARGHLELTREQRICAHEERKLAKATRKLDREkgvskKPAESRKTLKV------- 2168
Cdd:PRK02224 391 ----EEIEELRERFGD---APVDLGNAEDFLEELREERDELREREAELEATLRTARE-----RVEEAEALLEAgkcpecg 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2169 -LINLISKVRKVTQKESKMTKMNRSLLIKEAELSMEEKRLD-IKELEDTEEQPEIIMEERKLAkmERRLARqmRRLSTEE 2246
Cdd:PRK02224 459 qPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLErAEDLVEAEDRIERLEERREDL--EELIAE--RRETIEE 534
|
....*..
gi 2482565915 2247 KRMAEEE 2253
Cdd:PRK02224 535 KRERAEE 541
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1686-1998 |
1.87e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 50.28 E-value: 1.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1686 EEKLAQEERRLAQEEGKlaHEYVKSATKGGKLAHIEMTlGEKETFLSQQEEILSREAEF------LAQKKKKLARKLEKM 1759
Cdd:pfam07888 79 ESRVAELKEELRQSREK--HEELEEKYKELSASSEELS-EEKDALLAQRAAHEARIRELeediktLTQRVLERETELERM 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1760 AHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELalkEDELYEEAEKLEdkrEALAKE 1839
Cdd:pfam07888 156 KERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQL---QDTITTLTQKLT---TAHRKE 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1840 EEMLALYEKNLSLEEEMLAQEAKHQM--EEEKRLALEKDRRPEEVK-----------HLQERREKLREQKQRLAQEKERI 1906
Cdd:pfam07888 230 AENEALLEELRSLQERLNASERKVEGlgEELSSMAAQRDRTQAELHqarlqaaqltlQLADASLALREGRARWAQERETL 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1907 AQRKTELKVKKTRLA----QMEESLSQERhklsLEKERL-TERGKALHDKEKKLLKGKEQLQDIKGKLETY---REKLIN 1978
Cdd:pfam07888 310 QQSAEADKDRIEKLSaelqRLEERLQEER----MEREKLeVELGREKDCNRVQLSESRRELQELKASLRVAqkeKEQLQA 385
|
330 340
....*....|....*....|
gi 2482565915 1979 LSKKLMEEKTVFVAKKEKLT 1998
Cdd:pfam07888 386 EKQELLEYIRQLEQRLETVA 405
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1421-2005 |
2.32e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.45 E-value: 2.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1421 KDKEKEVAFLESEDVVKGKRRPRKGRKTRKtVKQEKMEKDERIEETISAEElavtlkpEEVAEEGEGRSKKRKGTWEEEE 1500
Cdd:PRK03918 196 KEKEKELEEVLREINEISSELPELREELEK-LEKEVKELEELKEEIEELEK-------ELESLEGSKRKLEEKIRELEER 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1501 GAEKREKEEEEeqmiepkeaitEAVERKLSWVEWKshwdewqkaqtqravlwedwkkqcdKKHFEEEARLRVEGKlqpSE 1580
Cdd:PRK03918 268 IEELKKEIEEL-----------EEKVKELKELKEK-------------------------AEEYIKLSEFYEEYL---DE 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1581 EVEEPKKMLTWDEWREVWENILHTKSEKELDLGEMFKEGEEEEEEEEEEIGEEEEEEEEEIYEEEAEGRKERRQIRMAQK 1660
Cdd:PRK03918 309 LREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1661 QARadwrqarGERRRAREKKLLAHEEEKLAQEERRLAQEEG--KLAHEYVKSATKGGKLAHIEMTLGEKETFLSQQEEIL 1738
Cdd:PRK03918 389 LEK-------ELEELEKAKEEIEEEISKITARIGELKKEIKelKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAEL 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1739 SReaefLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKavlaqKTETMMEKEKNLASEEKKVR-EEAKNQELDGQELAL 1817
Cdd:PRK03918 462 KR----IEKELKEIEEKERKLRKELRELEKVLKKESELI-----KLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKE 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1818 KEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAqEAKHQMEEEKRLALEK-DRRPEEVKHLQERREKLREQK 1896
Cdd:PRK03918 533 KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELA-ELLKELEELGFESVEElEERLKELEPFYNEYLELKDAE 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1897 QRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLS-LEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLETYREK 1975
Cdd:PRK03918 612 KELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEeLEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREE 691
|
570 580 590
....*....|....*....|....*....|
gi 2482565915 1976 LINLSKKLMEEKTVFVAKKEKLTVTEKKIE 2005
Cdd:PRK03918 692 IKKTLEKLKEELEEREKAKKELEKLEKALE 721
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
1733-2028 |
2.53e-05 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 49.15 E-value: 2.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1733 QQEEILSREAEFLAQKKKKLARKLEKMAHEKEKiaKKINKVEEV---KAVLAQKTETMMEKEKnlasEEKKVREEAKNQE 1809
Cdd:pfam13868 55 RALEEEEEKEEERKEERKRYRQELEEQIEEREQ--KRQEEYEEKlqeREQMDEIVERIQEEDQ----AEAEEKLEKQRQL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1810 LDGQELALKEDELYEEAEKLEDKREalakeEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERR 1889
Cdd:pfam13868 129 REEIDEFNEEQAEWKELEKEEEREE-----DERILEYLKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAER 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1890 EKLReqkQRLAQEKERIAQRKTELKVKKTRLAQMEEsLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKL 1969
Cdd:pfam13868 204 DELR---AKLYQEEQERKERQKEREEAEKKARQRQE-LQQAREEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQE 279
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 1970 ETYREKLINLS-----KKLMEEKTvfVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKE 2028
Cdd:pfam13868 280 EAEKRRMKRLEhrrelEKQIEERE--EQRAAEREEELEEGERLREEEAERRERIEEERQKKLKE 341
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1682-1848 |
2.92e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 48.00 E-value: 2.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1682 LAHEEEKLAQEERRLAQEEGKLAHEYVKSATKggkLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKklARKLEKMAH 1761
Cdd:COG1579 22 LEHRLKELPAELAELEDELAALEARLEAAKTE---LEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN--NKEYEALQK 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1762 EKEKIAKKIN-----------KVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQEldgqelalkedelyEEAEKLE 1830
Cdd:COG1579 97 EIESLKRRISdledeilelmeRIEELEEELAELEAELAELEAELEEKKAELDEELAELE--------------AELEELE 162
|
170 180
....*....|....*....|
gi 2482565915 1831 DKREALAK--EEEMLALYEK 1848
Cdd:COG1579 163 AEREELAAkiPPELLALYER 182
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1380-1945 |
2.97e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.06 E-value: 2.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1380 VSIDEEATREEVtgqeEMPEAGKQRLEKEEGLQEAEEEtQEKDKEKEVAFLESEdvVKGKRRPRKGRKTRKTVKQEKMEK 1459
Cdd:PRK03918 212 ISSELPELREEL----EKLEKEVKELEELKEEIEELEK-ELESLEGSKRKLEEK--IRELEERIEELKKEIEELEEKVKE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1460 DERIEEtiSAEELAVTLKPEEVAEEGEGRSKKRKGTWeeeegaekrekeeeeeqmiepkEAITEAVERKLSWVEWKSHWD 1539
Cdd:PRK03918 285 LKELKE--KAEEYIKLSEFYEEYLDELREIEKRLSRL----------------------EEEINGIEERIKELEEKEERL 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1540 EWQKAQTQravlwedwKKQCDKKHFEEEARL--RVEGKLQPSEEVEEPKKMLTWDEWREVWENILHTKSEKELDLGEMfk 1617
Cdd:PRK03918 341 EELKKKLK--------ELEKRLEELEERHELyeEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKI-- 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1618 egeeeeeeeeeeigeeeeeeeEEIYEEEAEGRKERRQIRMAQKQARADWRQARGERRRAREKKLLAH---EEEKLAQEER 1694
Cdd:PRK03918 411 ---------------------TARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEytaELKRIEKELK 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1695 RLAQEEGKLAHEYVKSAT---KGGKLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKIN 1771
Cdd:PRK03918 470 EIEEKERKLRKELRELEKvlkKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1772 KVEEVKAVLAQKTETMMEKEKNLASEEKKVRE---------EAKNQELDG-----QELALKEDELYEEAEKLEDKREALA 1837
Cdd:PRK03918 550 KLEELKKKLAELEKKLDELEEELAELLKELEElgfesveelEERLKELEPfyneyLELKDAEKELEREEKELKKLEEELD 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1838 KEEEMLALYEKNL-SLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVK 1916
Cdd:PRK03918 630 KAFEELAETEKRLeELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKA 709
|
570 580 590
....*....|....*....|....*....|..
gi 2482565915 1917 KTRLAQME---ESLSQERHKLSLEKERLTERG 1945
Cdd:PRK03918 710 KKELEKLEkalERVEELREKVKKYKALLKERA 741
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
1683-1905 |
3.10e-05 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 49.15 E-value: 3.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1683 AHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKKLARK---LEKM 1759
Cdd:pfam13868 110 IQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAEREEIEEEKereIARL 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1760 AHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKE 1839
Cdd:pfam13868 190 RAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAREEQIELKERRLAEEAEREEEEFERMLRK 269
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2482565915 1840 EEMLAlyeknlslEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKER 1905
Cdd:pfam13868 270 QAEDE--------EIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERLREEEAER 327
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
1713-2217 |
3.20e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 49.82 E-value: 3.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1713 KGGKLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAK--KINKVEEVKAVLAQKTEtMMEK 1790
Cdd:pfam10174 183 RTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKdtKISSLERNIRDLEDEVQ-MLKT 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1791 EKNLASEEKkvREEAKNQELD--------------GQELALKEDELYEEAEKLE-------DKREALAKEEEMLALYEKN 1849
Cdd:pfam10174 262 NGLLHTEDR--EEEIKQMEVYkshskfmknkidqlKQELSKKESELLALQTKLEtltnqnsDCKQHIEVLKESLTAKEQR 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1850 LS-LEEEM----LAQEAKHQMEEEK-----RLALEKDRRPEEVKHLQ------ERR------------EKLREQKQRLAQ 1901
Cdd:pfam10174 340 AAiLQTEVdalrLRLEEKESFLNKKtkqlqDLTEEKSTLAGEIRDLKdmldvkERKinvlqkkienlqEQLRDKDKQLAG 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1902 EKERIAQRKTELKVKKTRLAQMEESLSqerhklslEKERLTERGKALHDkeKKLLKGKEQLQDIKGKLETYREKLINLSK 1981
Cdd:pfam10174 420 LKERVKSLQTDSSNTDTALTTLEEALS--------EKERIIERLKEQRE--REDRERLEELESLKKENKDLKEKVSALQP 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1982 KLMEEKTVFVAKKEKLTVTEKKIEMEDMLLaeKQGKLAVEKVKlaKEITEVIQNSQLIREETEIIKEAEELTSEMK---- 2057
Cdd:pfam10174 490 ELTEKESSLIDLKEHASSLASSGLKKDSKL--KSLEIAVEQKK--EECSKLENQLKKAHNAEEAVRTNPEINDRIRlleq 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2058 RVAREKmelvgelEEPPKTeikEAILRRRRLAMHEVDLMKKrvSIEEKIlayedrllATEEKDAARGHLELTREQRICAH 2137
Cdd:pfam10174 566 EVARYK-------EESGKA---QAEVERLLGILREVENEKN--DKDKKI--------AELESLTLRQMKEQNKKVANIKH 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2138 ---EERKLAKATRKLDREKGVSKKPAESRKTLKVLINLISKVR-KVTQKESKMTKMNRSLLIKEAELS--MEEKRldiKE 2211
Cdd:pfam10174 626 gqqEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRqELDATKARLSSTQQSLAEKDGHLTnlRAERR---KQ 702
|
....*.
gi 2482565915 2212 LEDTEE 2217
Cdd:pfam10174 703 LEEILE 708
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
1861-1996 |
3.22e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 49.32 E-value: 3.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1861 AKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKER 1940
Cdd:PRK12705 27 KRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDNLENQ 106
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2482565915 1941 LTERGKALHDKEKKLLKGKEQLQDIKGKLETYREKLIN------LSKKLMEEKTVFVAKKEK 1996
Cdd:PRK12705 107 LEEREKALSARELELEELEKQLDNELYRVAGLTPEQARklllklLDAELEEEKAQRVKKIEE 168
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1686-1993 |
3.45e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 49.74 E-value: 3.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1686 EEKLAQEERRLAQEEGKLAheyvKSATKGGKLAHIEMTLGE-KETFLSQQEEI-----LSREAEFLAQKKKKL------- 1752
Cdd:pfam05557 227 KEEVEDLKRKLEREEKYRE----EAATLELEKEKLEQELQSwVKLAQDTGLNLrspedLSRRIEQLQQREIVLkeenssl 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1753 ---ARKLEKMAHEKE-KIAKKINKVEEVKAVLAQKTETM--MEKEKNLASEEKK-VREEAKN--QELDGQELALKEDELY 1823
Cdd:pfam05557 303 tssARQLEKARRELEqELAQYLKKIEDLNKKLKRHKALVrrLQRRVLLLTKERDgYRAILESydKELTMSNYSPQLLERI 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1824 EEAEKLEDK--------REALAKEEEMLALYEKNLS-LEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLRE 1894
Cdd:pfam05557 383 EEAEDMTQKmqahneemEAQLSVAEEELGGYKQQAQtLERELQALRQQESLADPSYSKEEVDSLRRKLETLELERQRLRE 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1895 QKQRLAQEKERIAQRKTeLKVKKTRLAQM--------EESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIK 1966
Cdd:pfam05557 463 QKNELEMELERRCLQGD-YDPKKTKVLHLsmnpaaeaYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMN 541
|
330 340
....*....|....*....|....*...
gi 2482565915 1967 GK-LETYREKLINLSKKLMEEKTVFVAK 1993
Cdd:pfam05557 542 FKeVLDLRKELESAELKNQRLKEVFQAK 569
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1748-2051 |
3.72e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 49.57 E-value: 3.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1748 KKKKLARK--LEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELAlkedELYEE 1825
Cdd:COG5185 225 AKEIINIEeaLKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTK----EKIAE 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1826 AEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKrlaLEKDRRPeevkhLQERREKLREQKQRLAQEkER 1905
Cdd:COG5185 301 YTKSIDIKKATESLEEQLAAAEAEQELEESKRETETGIQNLTAE---IEQGQES-----LTENLEAIKEEIENIVGE-VE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1906 IAQRKTELKVKKTRLAQMEESLSQERHKLsleKERLTERGKALHDKEKKLLKGKEQLQ-DIKGKLETYREKlINLSKKLM 1984
Cdd:COG5185 372 LSKSSEELDSFKDTIESTKESLDEIPQNQ---RGYAQEILATLEDTLKAADRQIEELQrQIEQATSSNEEV-SKLLNELI 447
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2482565915 1985 EEKtVFVAKKEKLTVTEKKIEMEDMLLAEKQgklaVEKVKLAKEITEVIQNSQLIREETEIIKEAEE 2051
Cdd:COG5185 448 SEL-NKVMREADEESQSRLEEAYDEINRSVR----SKKEDLNEELTQIESRVSTLKATLEKLRAKLE 509
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1857-2178 |
3.86e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 48.75 E-value: 3.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1857 LAQEAKHQMEEEKRLALEKDRRPEEVKHLQER----REKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERH 1932
Cdd:COG4372 29 LSEQLRKALFELDKLQEELEQLREELEQAREEleqlEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1933 KLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLME-EKTVFVAKKEKLTVTEKKIEMEdmll 2011
Cdd:COG4372 109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESlQEELAALEQELQALSEAEAEQA---- 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2012 AEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMKRVAREKMELVGELEEPPKTEIKEAILRRRRLAMH 2091
Cdd:COG4372 185 LDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2092 EVDLMKKRVSIEEKILAYEDRLLATEEKDAARGHLELTREQRICAHEERKLAKATRKLDREKGVSKKPAESRKTLKVLIN 2171
Cdd:COG4372 265 LAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQ 344
|
....*..
gi 2482565915 2172 LISKVRK 2178
Cdd:COG4372 345 LLLVGLL 351
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1729-1947 |
4.07e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.99 E-value: 4.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1729 TFLSQQEEILSREAEfLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKV-----RE 1803
Cdd:COG4942 14 AAAAQADAAAEAEAE-LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELaelekEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1804 EAKNQELDGQELALKE--DELY--EEAEKLE-----DKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALE 1874
Cdd:COG4942 93 AELRAELEAQKEELAEllRALYrlGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2482565915 1875 KDRRPEEVKHLQERREKLR----EQKQRLAQEKERIAQRKTELKvkktRLAQMEESLSQERHKLSLEKERLTERGKA 1947
Cdd:COG4942 173 RAELEALLAELEEERAALEalkaERQKLLARLEKELAELAAELA----ELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| ERM_helical |
pfam20492 |
Ezrin/radixin/moesin, alpha-helical domain; The ERM family consists of three closely-related ... |
1782-1894 |
4.61e-05 |
|
Ezrin/radixin/moesin, alpha-helical domain; The ERM family consists of three closely-related proteins, ezrin, radixin and moesin. Ezrin was first identified as a constituent of microvilli, radixin as a barbed, end-capping actin-modulating protein from isolated junctional fractions, and moesin as a heparin binding protein. A tumour suppressor molecule responsible for neurofibromatosis type 2 (NF2) is highly similar to ERM proteins and has been designated merlin (moesin-ezrin-radixin-like protein). ERM molecules contain 3 domains, an N-terminal globular domain, an extended alpha-helical domain and a charged C-terminal domain (pfam00769). Ezrin, radixin and merlin also contain a polyproline linker region between the helical and C-terminal domains. The N-terminal domain is highly conserved and is also found in merlin, band 4.1 proteins and members of the band 4.1 superfamily, designated the FERM domain. ERM proteins crosslink actin filaments with plasma membranes. They co-localize with CD44 at actin filament plasma membrane interaction sites, associating with CD44 via their N-terminal domains and with actin filaments via their C-terminal domains. This is the alpha-helical domain, which is involved in intramolecular masking of protein-protein interaction sites, regulating the activity of this proteins.
Pssm-ID: 466641 [Multi-domain] Cd Length: 120 Bit Score: 45.29 E-value: 4.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1782 QKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALyEKNLSLEE-EMLAQE 1860
Cdd:pfam20492 6 REKQELEERLKQYEEETKKAQEELEESEETAEELEEERRQAEEEAERLEQKRQEAEEEKERLEE-SAEMEAEEkEQLEAE 84
|
90 100 110
....*....|....*....|....*....|....
gi 2482565915 1861 AKHQMEEEKRLALEKDRRPEEVKHLQERREKLRE 1894
Cdd:pfam20492 85 LAEAQEEIARLEEEVERKEEEARRLQEELEEARE 118
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1824-2206 |
4.97e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 48.74 E-value: 4.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1824 EEAEKLEDKREALAKEEEMLALYEKNLSLE---EEMLAQEAK-HQMEEEKRLALEKDRRPEEVKHLQ--ERREKLREQKQ 1897
Cdd:pfam07888 4 DELVTLEEESHGEEGGTDMLLVVPRAELLQnrlEECLQERAElLQAQEAANRQREKEKERYKRDREQweRQRRELESRVA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1898 RLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDkekKLLKGKEQLQDIKGKLETYREKLI 1977
Cdd:pfam07888 84 ELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEE---DIKTLTQRVLERETELERMKERAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1978 NLSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMk 2057
Cdd:pfam07888 161 KAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEEL- 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2058 RVAREKMELVGELEEPPKTEIKEAILRRRRLamhEVDLMKKRVSIEEKILAYEDRLLATEEkDAARGHLELTREQRICAH 2137
Cdd:pfam07888 240 RSLQERLNASERKVEGLGEELSSMAAQRDRT---QAELHQARLQAAQLTLQLADASLALRE-GRARWAQERETLQQSAEA 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 2138 EERKLAKATRKLDR-EKGVSKKPAEsRKTLKVLINLISKVRKVTQKESK--MTKMNRSL--LIKEAELSMEEKR 2206
Cdd:pfam07888 316 DKDRIEKLSAELQRlEERLQEERME-REKLEVELGREKDCNRVQLSESRreLQELKASLrvAQKEKEQLQAEKQ 388
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
1716-1950 |
4.98e-05 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 49.13 E-value: 4.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1716 KLAHIEMTLGEKETFLSQQEEILSREAEFLAQKKKKLARKLEKMahEKEKIAKKINKVEEVKAVLAQKTETMME----KE 1791
Cdd:PRK01156 466 KSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYL--ESEEINKSINEYNKIESARADLEDIKIKinelKD 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1792 KNLASEEKKVRE--------EAKNQE----------LDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNL--S 1851
Cdd:PRK01156 544 KHDKYEEIKNRYkslkledlDSKRTSwlnalavislIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSirE 623
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1852 LEEEMLAQEAKHQMEEEKRLALEKDRrpEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQER 1931
Cdd:PRK01156 624 IENEANNLNNKYNEIQENKILIEKLR--GKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLE 701
|
250
....*....|....*....
gi 2482565915 1932 HKLSLEKERLTERGKALHD 1950
Cdd:PRK01156 702 STIEILRTRINELSDRIND 720
|
|
| TolA |
COG3064 |
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis]; |
1649-2124 |
5.08e-05 |
|
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 48.88 E-value: 5.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1649 RKERRQIRMAQKQARADWRQARGERRRAREKKLLAHEEEKLAQEERRLAQEEGKLAHEYVKSatkggklahiemtlgEKE 1728
Cdd:COG3064 12 AAAQERLEQAEAEKRAAAEAEQKAKEEAEEERLAELEAKRQAEEEAREAKAEAEQRAAELAA---------------EAA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1729 TFLSQQEEILSREAEFLAQKKKKLARKLEKMAH-EKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKN 1807
Cdd:COG3064 77 KKLAEAEKAAAEAEKKAAAEKAKAAKEAEAAAAaEKAAAAAEKEKAEEAKRKAEEEAKRKAEEERKAAEAEAAAKAEAEA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1808 QELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQE 1887
Cdd:COG3064 157 ARAAAAAAAAAAAAAARAAAGAAAALVAAAAAAVEAADTAAAAAAALAAAAAAAAADAALLALAVAARAAAASREAALAA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1888 RREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKG 1967
Cdd:COG3064 237 VEATEEAALGGAEEAADLAAVGVLGAALAAAAAGAAALSSGLVVVAAALAGLAAAAAGLVLDDSAALAAELLGAVAAEEA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1968 KLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIK 2047
Cdd:COG3064 317 VLAAAAAAGALVVRGGGAASLEAALSLLAAGAAAAAAGAGALATGALGDALAAEAAGALLLGKLADVEEAAGAGILAAAG 396
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2482565915 2048 EAEELTSEMKRVAREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRLLATEEKDAARG 2124
Cdd:COG3064 397 GGGLLGLRLDLGAALLEAASAVELRVLLALAGAAGAVVALLVKLVADLAGGLVGIGKALTGDADALLGILKAVALDG 473
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1680-1976 |
5.22e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 49.35 E-value: 5.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1680 KLLAHEEEKLaQEERRLAQEEGKLAHeyVKSATKGGKLahiemTLGEKETFLsqqeEILSREAEFLAQKKKKLARKLEKM 1759
Cdd:pfam15921 521 KLRSRVDLKL-QELQHLKNEGDHLRN--VQTECEALKL-----QMAEKDKVI----EILRQQIENMTQLVGQHGRTAGAM 588
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1760 AHEKEKIAKKIN----KVEEVKAVLAQKTETMMEKEKNLASEE-KKVR-EEAKNQELDG-QELALKEDELYEEAEKLEDK 1832
Cdd:pfam15921 589 QVEKAQLEKEINdrrlELQEFKILKDKKDAKIRELEARVSDLElEKVKlVNAGSERLRAvKDIKQERDQLLNEVKTSRNE 668
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1833 REALAKEEEMLALYEKNLSLEEEMLAQEAKHQME------EEKRLALEK--------------------------DRRPE 1880
Cdd:pfam15921 669 LNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKsaqselEQTRNTLKSmegsdghamkvamgmqkqitakrgqiDALQS 748
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1881 EVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLA-QMEESLSQERhklslekeRLTERGKALHDKEKKLLKGK 1959
Cdd:pfam15921 749 KIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAgELEVLRSQER--------RLKEKVANMEVALDKASLQF 820
|
330
....*....|....*....
gi 2482565915 1960 EQLQDI--KGKLETYREKL 1976
Cdd:pfam15921 821 AECQDIiqRQEQESVRLKL 839
|
|
| YkyA |
pfam10368 |
Putative cell-wall binding lipoprotein; YkyA is a family of proteins containing a lipoprotein ... |
1719-1860 |
5.32e-05 |
|
Putative cell-wall binding lipoprotein; YkyA is a family of proteins containing a lipoprotein signal and a hydrolase domain. It is similar to cell wall binding proteins and might also be recognisable by a host immune defence system. It is thus likely to belong to pathways important for pathogenicity.
Pssm-ID: 431235 [Multi-domain] Cd Length: 185 Bit Score: 46.43 E-value: 5.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1719 HIEMTLGEKETFLSQQEEILSREaeflaQKKKKLARK-LEKMAHEKEKIAKKINKVEEvkavLAQKTETMMEKEKNLASE 1797
Cdd:pfam10368 9 HLEEAVELEKPFEEQQEPLVELE-----KKEQELYEEiIELGMDEFDEIKKLSDEALE----NVEEREELLEKEKESIEE 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2482565915 1798 EKKVREEAKNQELDgqelaLKEDELYEEAEKLEDKREALAKE-EEMLALYEKNLSLEEE---MLAQE 1860
Cdd:pfam10368 80 AKEEFKKIKEIIEE-----IEDEELKKEAEELIDAMEERYEAyDELYDAYKKALELDKElyeMLKDE 141
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
1726-1977 |
5.66e-05 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 48.27 E-value: 5.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1726 EKETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINkveevkAVLAQKTETmmekEKNLASEEKKVREEA 1805
Cdd:pfam15905 66 QKNLKESKDQKELEKEIRALVQERGEQDKRLQALEEELEKVEAKLN------AAVREKTSL----SASVASLEKQLLELT 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1806 KNQEL---------DGQELALKEDELYEEAEKLEDK-REALAKEEEM---LALYEKNLSLEEEMLAQEAKHQMEEEKRLA 1872
Cdd:pfam15905 136 RVNELlkakfsedgTQKKMSSLSMELMKLRNKLEAKmKEVMAKQEGMegkLQVTQKNLEHSKGKVAQLEEKLVSTEKEKI 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1873 LEKdrrpEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKAL-HDK 1951
Cdd:pfam15905 216 EEK----SETEKLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQIKDLNEKCKLLeSEK 291
|
250 260
....*....|....*....|....*.
gi 2482565915 1952 EKKLLKGKEQLQDIKGKLETYREKLI 1977
Cdd:pfam15905 292 EELLREYEEKEQTLNAELEELKEKLT 317
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
1685-2024 |
7.25e-05 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 48.60 E-value: 7.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1685 EEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHIEMTLGEKETFLSQQEEI-LSREAEFLAQKKKKLARKLEKMAHEK 1763
Cdd:pfam09731 86 KKQVKIPRQSGVSSEVAEEEKEATKDAAEAKAQLPKSEQEKEKALEEVLKEAIsKAESATAVAKEAKDDAIQAVKAHTDS 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1764 EK---IAKKINKVEEVkAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEdeLYEEAEKLEDKREALAKEE 1840
Cdd:pfam09731 166 LKeasDTAEISREKAT-DSALQKAEALAEKLKEVINLAKQSEEEAAPPLLDAAPETPPK--LPEHLDNVEEKVEKAQSLA 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1841 EMLALYEKNLSLEEEMLAQEAKHQMEE-----EKRLALEKDRRPEEVKHLQERREKLREQKQRL-AQEKERI-----AQR 1909
Cdd:pfam09731 243 KLVDQYKELVASERIVFQQELVSIFPDiipvlKEDNLLSNDDLNSLIAHAHREIDQLSKKLAELkKREEKHIeraleKQK 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1910 KTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQ------LQD--IKGKLETYREKLINLSK 1981
Cdd:pfam09731 323 EELDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTELERQAeaheehLKDvlVEQEIELQREFLQDIKE 402
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 2482565915 1982 KLMEEKTVFVAKKEKLTVTEKKIEM--------EDMLLAEKQGKLAVEKVK 2024
Cdd:pfam09731 403 KVEEERAGRLLKLNELLANLKGLEKatsshsevEDENRKAQQLWLAVEALR 453
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1880-2213 |
7.34e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.97 E-value: 7.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1880 EEVKHLQERREKLREQKQRLAQEKER----IAQRKTELKVKKTRLAQMEESLSQERHKLSLEKErltergkalhdkekkl 1955
Cdd:COG4372 38 FELDKLQEELEQLREELEQAREELEQleeeLEQARSELEQLEEELEELNEQLQAAQAELAQAQE---------------- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1956 lkgkeQLQDIKGKLETYREKLinlsKKLMEEKTVFVAKKEKLTVTEKKIEmEDMLLAEKQGKLAVEKVKLAKEITEVIQN 2035
Cdd:COG4372 102 -----ELESLQEEAEELQEEL----EELQKERQDLEQQRKQLEAQIAELQ-SEIAEREEELKELEEQLESLQEELAALEQ 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2036 SQLIREETEIIKEAEELTSEMKRVAREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRLLA 2115
Cdd:COG4372 172 ELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEEL 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2116 TEEKDAARGHLELTREQRICAHEERKLAKATRKLDREKgVSKKPAESRKTLKVLINLISKVRKVTQKESKMTKMNRSLLI 2195
Cdd:COG4372 252 LEEVILKEIEELELAILVEKDTEEEELEIAALELEALE-EAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLEL 330
|
330
....*....|....*...
gi 2482565915 2196 KEAELSMEEKRLDIKELE 2213
Cdd:COG4372 331 ALAILLAELADLLQLLLV 348
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
1649-1854 |
8.26e-05 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 47.88 E-value: 8.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1649 RKERRQIRMAQKQA---RADWRQARGERRRAREKKLLAHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAhiemtlG 1725
Cdd:PRK09510 76 RAEEQRKKKEQQQAeelQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAKAK------A 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1726 EKEtflSQQEEILSREAEflAQKKKKLARKLEKMAHEKEKiaKKINKVEEVKAV-LAQKTETMMEKEKNLASEEKKVREE 1804
Cdd:PRK09510 150 EAE---AKRAAAAAKKAA--AEAKKKAEAEAAKKAAAEAK--KKAEAEAAAKAAaEAKKKAEAEAKKKAAAEAKKKAAAE 222
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1805 AKnqeldgqelalKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEE 1854
Cdd:PRK09510 223 AK-----------AAAAKAAAEAKAAAEKAAAAKAAEKAAAAKAAAEVDD 261
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
1866-2119 |
8.62e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.21 E-value: 8.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1866 EEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERG 1945
Cdd:COG1340 8 SSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1946 KALHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLM-------EEKTVFvakkEKLTVTEKKIEmedmlLAEKQGKL 2018
Cdd:COG1340 88 NELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQtevlspeEEKELV----EKIKELEKELE-----KAKKALEK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2019 AVEKVKLAKEITEV-IQNSQLIREETEIIKEAEELTSEMKRVAREKMELVGELEEpPKTEIKEAILRRRRLAMHEVDLMK 2097
Cdd:COG1340 159 NEKLKELRAELKELrKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADE-LHKEIVEAQEKADELHEEIIELQK 237
|
250 260
....*....|....*....|..
gi 2482565915 2098 KRVSIEEKILAYEDRLLATEEK 2119
Cdd:COG1340 238 ELRELRKELKKLRKKQRALKRE 259
|
|
| MAP7 |
pfam05672 |
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ... |
1789-1909 |
8.99e-05 |
|
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.
Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 45.42 E-value: 8.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1789 EKEKNLASEEKKVREEAKNQEldgqelalKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEE 1868
Cdd:pfam05672 11 EAARILAEKRRQAREQREREE--------QERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEERQRKAE 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2482565915 1869 KRLALEKDRRPEEVKHLQERRE----KLREQKQRLAQEKERIAQR 1909
Cdd:pfam05672 83 EEAEEREQREQEEQERLQKQKEeaeaKAREEAERQRQEREKIMQQ 127
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1722-2206 |
9.52e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 48.36 E-value: 9.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1722 MTLGEKETFLSQQEEILSREAEFLAQKKKKLA-----RKLEKMAHEKEKIAKKINK-VEEVKAVLAQKTETMMEKEKNLA 1795
Cdd:PLN02939 1 AAAAESAALLSHGCGPIRSRAPFYLPSRRRLAvscraRRRGFSSQQKKKRGKNIAPkQRSSNSKLQSNTDENGQLENTSL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1796 SEEKKVREEAKNQELDGQELALKEDElyeEAEKLEDKREALAKEEE------------MLALYEKNLsleeeMLAQEAKH 1863
Cdd:PLN02939 81 RTVMELPQKSTSSDDDHNRASMQRDE---AIAAIDNEQQTNSKDGEqlsdfqledlvgMIQNAEKNI-----LLLNQARL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1864 Q-MEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLT 1942
Cdd:PLN02939 153 QaLEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1943 ERGKALHDkekkllkgkeqlqDIkgklETYREKLINLSKKlmeEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEK 2022
Cdd:PLN02939 233 EENMLLKD-------------DI----QFLKAELIEVAET---EERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSP 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2023 VKLaKEITEVIQNSQLIREETEIIKEAEELTSEMKRVAREKmelVGELEEppktEIKEAILrrRRLAMHEVDLMkkrvsi 2102
Cdd:PLN02939 293 LQY-DCWWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDK---VDKLEA----SLKEANV--SKFSSYKVELL------ 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2103 EEKILAYEDRLLATEEKdaARGHLELTREQRICAHEE-RKLAKATRKLDREKGVSKKPAESRKTLKVLINLISKVRKVTQ 2181
Cdd:PLN02939 357 QQKLKLLEERLQASDHE--IHSYIQLYQESIKEFQDTlSKLKEESKKRSLEHPADDMPSEFWSRILLLIDGWLLEKKISN 434
|
490 500
....*....|....*....|....*...
gi 2482565915 2182 KESKMTK---MNRSLLIKEAELSMEEKR 2206
Cdd:PLN02939 435 NDAKLLRemvWKRDGRIREAYLSCKGKN 462
|
|
| Borrelia_P83 |
pfam05262 |
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins. |
1720-1902 |
1.02e-04 |
|
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
Pssm-ID: 114011 [Multi-domain] Cd Length: 489 Bit Score: 47.69 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1720 IEMTLGEKETFLSQQEEIL---SREAEFLAQKKKKLARKLEKMAHEKEKIAKKinkveevkavlAQKTETMMEKEKNLAS 1796
Cdd:pfam05262 183 VEALREDNEKGVNFRRDMTdlkERESQEDAKRAQQLKEELDKKQIDADKAQQK-----------ADFAQDNADKQRDEVR 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1797 EEKKvreEAKNQELDGQELALKEDELYEEAEKLEDKR---EALAKEEEMLalyeKNLSLEEEMLAQEAKhqmEEEKRL-- 1871
Cdd:pfam05262 252 QKQQ---EAKNLPKPADTSSPKEDKQVAENQKREIEKaqiEIKKNDEEAL----KAKDHKAFDLKQESK---ASEKEAed 321
|
170 180 190
....*....|....*....|....*....|...
gi 2482565915 1872 -ALEKDRRPEEV-KHLQERREKLREQKQRLAQE 1902
Cdd:pfam05262 322 kELEAQKKREPVaEDLQKTKPQVEAQPTSLNED 354
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1743-1909 |
1.07e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 1.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1743 EFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEkEKNLASEEKKVRE--------EAKNQELDGQE 1814
Cdd:COG4913 613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWD-EIDVASAEREIAEleaelerlDASSDDLAALE 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1815 LALKE-----DELYEEAEKLEDKREALAKE----EEMLALYEKNLSlEEEMLAQEAKHQMEEEKRLALEKDRRPEEV-KH 1884
Cdd:COG4913 692 EQLEEleaelEELEEELDELKGEIGRLEKEleqaEEELDELQDRLE-AAEDLARLELRALLEERFAAALGDAVERELrEN 770
|
170 180
....*....|....*....|....*
gi 2482565915 1885 LQERREKLREQKQRLAQEKERIAQR 1909
Cdd:COG4913 771 LEERIDALRARLNRAEEELERAMRA 795
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
597-634 |
1.11e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 41.56 E-value: 1.11e-04
10 20 30
....*....|....*....|....*....|....*...
gi 2482565915 597 KFIETLPLHQCPITSFDVCLSLNVFATGGSDGTVRLWD 634
Cdd:pfam00400 2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1601-2052 |
1.50e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 47.71 E-value: 1.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1601 ILHTKSEKELDLGEMFKEGEeeeeeeeeeigeeeeeeeeeiyeeeaegRKERRQIRMAQKQaradwrqargerrrarekk 1680
Cdd:TIGR04523 297 ISDLNNQKEQDWNKELKSEL----------------------------KNQEKKLEEIQNQ------------------- 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1681 lLAHEEEKLAQEERRLAQeegklaheyvksatkggklahIEMTLGEKET-FLSQQEEILSREAEFLAQKKKKLARK--LE 1757
Cdd:TIGR04523 330 -ISQNNKIISQLNEQISQ---------------------LKKELTNSESeNSEKQRELEEKQNEIEKLKKENQSYKqeIK 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1758 KMAHEKEKIAKKINKVEEVKAVLAQKTETmMEKEKNLASEE-KKVREEAKNQELDGQELALKEDELYEEAEKLEDKREAL 1836
Cdd:TIGR04523 388 NLESQINDLESKIQNQEKLNQQKDEQIKK-LQQEKELLEKEiERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1837 AKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIaqrKTELKVK 1916
Cdd:TIGR04523 467 ETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEK---ESKISDL 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1917 KTRLAQMEESLSQErhKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLETYREKLInlskKLMEEKTVFVAKKEK 1996
Cdd:TIGR04523 544 EDELNKDDFELKKE--NLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLI----KEIEEKEKKISSLEK 617
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1997 -LTVTEK---KIEMEDMLLAEKQGKLaVEKVKLAKEITEVIQNSqlireETEIIKEAEEL 2052
Cdd:TIGR04523 618 eLEKAKKeneKLSSIIKNIKSKKNKL-KQEVKQIKETIKEIRNK-----WPEIIKKIKES 671
|
|
| CAF-1_p150 |
pfam11600 |
Chromatin assembly factor 1 complex p150 subunit, N-terminal; CAF-1_p150 is a polypeptide ... |
1824-1942 |
1.52e-04 |
|
Chromatin assembly factor 1 complex p150 subunit, N-terminal; CAF-1_p150 is a polypeptide subunit of CAF-1, which functions in depositing newly synthesized and acetylated histones H3/H4 into chromatin during DNA replication and repair. CAF-1_p150 includes the HP1 interaction site, the PEST, KER and ED interacting sites. CAF-1_p150 interacts directly with newly synthesized and acetylated histones through the acidic KER and ED domains. The PEST domain is associated with proteins that undergo rapid proteolysis.
Pssm-ID: 402959 [Multi-domain] Cd Length: 164 Bit Score: 45.06 E-value: 1.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1824 EEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEK 1903
Cdd:pfam11600 13 KEKQRLEKDKERLRRQLKLEAEKEEKERLKEEAKAEKERAKEEARRKKEEEKELKEKERREKKEKDEKEKAEKLRLKEEK 92
|
90 100 110
....*....|....*....|....*....|....*....
gi 2482565915 1904 ERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLT 1942
Cdd:pfam11600 93 RKEKQEALEAKLEEKRKKEEEKRLKEEEKRIKAEKAEIT 131
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
1733-1926 |
1.58e-04 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 47.11 E-value: 1.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1733 QQEEILSREAEFLAQKKKKLARKLEKMAHEKEKiAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDG 1812
Cdd:PRK09510 80 QRKKKEQQQAEELQQKQAAEQERLKQLEKERLA-AQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAKAKAEAEAKRAAA 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1813 QELALKEDELYEEAEKLEDKREALAKEEEMLALYEKnlsleeemLAQEAKHQMEEEkrlALEKDRRPEEVKHLQERREKl 1892
Cdd:PRK09510 159 AAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAK--------AAAEAKKKAEAE---AKKKAAAEAKKKAAAEAKAA- 226
|
170 180 190
....*....|....*....|....*....|....
gi 2482565915 1893 reqKQRLAQEKERIAQRKTELKVKKTRLAQMEES 1926
Cdd:PRK09510 227 ---AAKAAAEAKAAAEKAAAAKAAEKAAAAKAAA 257
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
1751-1949 |
1.59e-04 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 46.98 E-value: 1.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1751 KLARKLEKMAHEKEKiAKkiNKVEEVKAVLAQKTEtmmekeknlasEEKKVREEAKNQELDGQELALKEDELYEEAEKLE 1830
Cdd:pfam19220 31 QLIEPIEAILRELPQ-AK--SRLLELEALLAQERA-----------AYGKLRRELAGLTRRLSAAEGELEELVARLAKLE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1831 DK-REA-LAKEEEMLALYEKNLSLE--EEMLAQEAKHQ---MEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEK 1903
Cdd:pfam19220 97 AAlREAeAAKEELRIELRDKTAQAEalERQLAAETEQNralEEENKALREEAQAAEKALQRAEGELATARERLALLEQEN 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2482565915 1904 eRIAQRKTELKVKKT-----RLAQMEESLSQERHKLSLEKERL----TERGKALH 1949
Cdd:pfam19220 177 -RRLQALSEEQAAELaeltrRLAELETQLDATRARLRALEGQLaaeqAERERAEA 230
|
|
| PspA_IM30 |
pfam04012 |
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ... |
1750-1937 |
1.63e-04 |
|
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.
Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 45.83 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1750 KKLARKLEKMAHEKekiakkINKVEEVKAVLAQKTETMmekeknlASEEKKVREEAKNQELDGQELALKEDELYEEAEKL 1829
Cdd:pfam04012 3 KRLGRLVRANIHEG------LDKAEDPEKMLEQAIRDM-------QSELVKARQALAQTIARQKQLERRLEQQTEQAKKL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1830 EDK-REALAKEEEMLAlyeknlsleEEMLAQEAKHqmeeEKRLALEKdrrpEEVKHLQERREKLREQKQRLAQekeRIAQ 1908
Cdd:pfam04012 70 EEKaQAALTKGNEELA---------REALAEKKSL----EKQAEALE----TQLAQQRSAVEQLRKQLAALET---KIQQ 129
|
170 180 190
....*....|....*....|....*....|.
gi 2482565915 1909 RKTELKVKKTRL--AQMEESLSQERHKLSLE 1937
Cdd:pfam04012 130 LKAKKNLLKARLkaAKAQEAVQTSLGSLSTS 160
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
1721-1902 |
2.15e-04 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 46.87 E-value: 2.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1721 EMTLGEKETFLSQQEEILSREAEFLaQKKKKLARKLEKmahEKEKIAKKINKVeevKAVLAQKTETMMEKEKNLASEEKK 1800
Cdd:pfam15709 344 EMRRLEVERKRREQEEQRRLQQEQL-ERAEKMREELEL---EQQRRFEEIRLR---KQRLEEERQRQEEEERKQRLQLQA 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1801 VREEAKNQ--ELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLS--LEEEMLAQEAKHQMEEEKRLALEKD 1876
Cdd:pfam15709 417 AQERARQQqeEFRRKLQELQRKKQQEEAERAEAEKQRQKELEMQLAEEQKRLMemAEEERLEYQRQKQEAEEKARLEAEE 496
|
170 180
....*....|....*....|....*.
gi 2482565915 1877 RRPEEVKHLQERREKLREQKQRLAQE 1902
Cdd:pfam15709 497 RRQKEEEAARLALEEAMKQAQEQARQ 522
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1766-1934 |
2.26e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.69 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1766 IAKKINkveEVKAVLAQKtetmmEKEKNLASEEKKVREEAKNQELDGQELALKedeLYEEAEK-LEDKREALAKEEemla 1844
Cdd:PRK12704 24 VRKKIA---EAKIKEAEE-----EAKRILEEAKKEAEAIKKEALLEAKEEIHK---LRNEFEKeLRERRNELQKLE---- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1845 lyeKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTElKVKKTRLAQME 1924
Cdd:PRK12704 89 ---KRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAE-EAKEILLEKVE 164
|
170
....*....|
gi 2482565915 1925 ESLSQERHKL 1934
Cdd:PRK12704 165 EEARHEAAVL 174
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
1750-2133 |
2.52e-04 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 46.64 E-value: 2.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1750 KKLARKLEKMAHEKEKIAKKINKVEEVkAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKL 1829
Cdd:COG2770 241 RRLAEAARRIAAGDLDVRIPVSRKDEI-GELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLA 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1830 EDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQR 1909
Cdd:COG2770 320 LLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALA 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1910 KTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLMEEKTV 1989
Cdd:COG2770 400 AALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALL 479
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1990 FVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMKRVAREKMELVGE 2069
Cdd:COG2770 480 LLAALGALELLLLEEEEEAGAAAEELAEELLLLEGLLLLLLLEAEALEVAEELLELEEAALLLAAAAELAALLALLLALA 559
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 2070 LEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRLLATEEKDAARGHLELTREQR 2133
Cdd:COG2770 560 AVEAAALLLAALLLAAVAALLELAALLLLLLAAAEALAALELELAAAAEAALAEAELLEVAAAA 623
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1649-1983 |
2.68e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.68 E-value: 2.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1649 RKERRQIRMAQKQARADWRQARGERRRAREKKLLAHEEEKLAQEERRLAQEEGKLaheyvksatkggklahiemtlgekE 1728
Cdd:COG4717 101 EEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERL------------------------E 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1729 TFLSQQEEILSREAEfLAQKKKKLARKLEKMAHEKEKIAKKI--------NKVEEVKAVLAQKTETMMEKEKNLASEEKK 1800
Cdd:COG4717 157 ELRELEEELEELEAE-LAELQEELEELLEQLSLATEEELQDLaeeleelqQRLAELEEELEEAQEELEELEEELEQLENE 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1801 VREEAKNQELDGQE-----------LALKEDELYEEAE------------------KLEDKREALAKEEEMLALYEKNLS 1851
Cdd:COG4717 236 LEAAALEERLKEARlllliaaallaLLGLGGSLLSLILtiagvlflvlgllallflLLAREKASLGKEAEELQALPALEE 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1852 LEEEMLAQEAKHQM---EEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKER---IAQRKTELKVKKTRLAQMEE 1925
Cdd:COG4717 316 LEEEELEELLAALGlppDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIaalLAEAGVEDEEELRAALEQAE 395
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1926 SLSQERHKLSLEKERLTERGKALHDKEKKLLKGK--EQLQDIKGKLETYREKLINLSKKL 1983
Cdd:COG4717 396 EYQELKEELEELEEQLEELLGELEELLEALDEEEleEELEELEEELEELEEELEELREEL 455
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1734-1881 |
2.80e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.98 E-value: 2.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1734 QEEILSREAEfLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVkAVLAQKT--------------------------ETM 1787
Cdd:COG3883 50 NEEYNELQAE-LEALQAEIDKLQAEIAEAEAEIEERREELGER-ARALYRSggsvsyldvllgsesfsdfldrlsalSKI 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1788 MEKEKNLASEEKKVREEAKNQEldgQELALKEDELYEEAEKLEDKREAL-AKEEEMLALYEKnLSLEEEMlAQEAKHQME 1866
Cdd:COG3883 128 ADADADLLEELKADKAELEAKK---AELEAKLAELEALKAELEAAKAELeAQQAEQEALLAQ-LSAEEAA-AEAQLAELE 202
|
170
....*....|....*
gi 2482565915 1867 EEKRLALEKDRRPEE 1881
Cdd:COG3883 203 AELAAAEAAAAAAAA 217
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
1727-1924 |
3.10e-04 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 46.48 E-value: 3.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1727 KETFLSQQEEILSREAEFLAQKKKKlaRKLEKMAHEKEKIAKKINKVEEVKAvlAQKTETMMEKEKNLASEEKKVREEAK 1806
Cdd:pfam15709 321 SKALLEKREQEKASRDRLRAERAEM--RRLEVERKRREQEEQRRLQQEQLER--AEKMREELELEQQRRFEEIRLRKQRL 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1807 NQELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLAlekdrrpEEVKHLQ 1886
Cdd:pfam15709 397 EEERQRQEEEERKQRLQLQAAQERARQQQEEFRRKLQELQRKKQQEEAERAEAEKQRQKELEMQLA-------EEQKRLM 469
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2482565915 1887 ERREKLREQKQRLAQEKERIAQRKTELKVKK----TRLAQME 1924
Cdd:pfam15709 470 EMAEEERLEYQRQKQEAEEKARLEAEERRQKeeeaARLALEE 511
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1824-2038 |
3.12e-04 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 46.36 E-value: 3.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1824 EEAEKLED---KREALAKEEEmlalyEKNLSLEEEMLAQEAKHQMEEEKrlaLEKdrrpeevkhLQERREKLREQKQRLA 1900
Cdd:PRK00409 513 EDKEKLNEliaSLEELERELE-----QKAEEAEALLKEAEKLKEELEEK---KEK---------LQEEEDKLLEEAEKEA 575
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1901 QEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQ--DiKGKLETYREKLIN 1978
Cdd:PRK00409 576 QQAIKEAKKEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELKvgD-EVKYLSLGQKGEV 654
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1979 LSKKLMEEKTVFVAKKeKLTVTEKKIemedmllaEKQGKLAVEKVKLAKEITEVIQNSQL 2038
Cdd:PRK00409 655 LSIPDDKEAIVQAGIM-KMKVPLSDL--------EKIQKPKKKKKKKPKTVKPKPRTVSL 705
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
379-664 |
3.77e-04 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 45.67 E-value: 3.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 379 RILCATEDGLLRFVSPVTGDLLLITWPFSVLDHAVdwAYDPNKEELFVATGTSEVLVFDASRNPCpvkylLCTSPDIQDY 458
Cdd:COG2319 92 LLASASADGTVRLWDLATGLLLRTLTGHTGAVRSV--AFSPDGKTLASGSADGTVRLWDLATGKL-----LRTLTGHSGA 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 459 VQCLAY---GNfhlgrglegLMFSGHQSGMIRVLSQHSCARIEK-NVHFGAVLALSIfygglmtSRENSLLCSYGVDDYI 534
Cdd:COG2319 165 VTSVAFspdGK---------LLASGSDDGTVRLWDLATGKLLRTlTGHTGAVRSVAF-------SPDGKLLASGSADGTV 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 535 QLSEaVLTGARLQLKTL--ACILSscplkhLVLLPK----AVGAITSTncLRLWKLrefisfgssQGIKFIETLPLHQCP 608
Cdd:COG2319 229 RLWD-LATGKLLRTLTGhsGSVRS------VAFSPDgrllASGSADGT--VRLWDL---------ATGELLRTLTGHSGG 290
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2482565915 609 ITSfdVCLSLN--VFATGGSDGTVRLWDFQ-GRLIAMLDSslHFGP---LCFANDrGDLLVT 664
Cdd:COG2319 291 VNS--VAFSPDgkLLASGSDDGTVRLWDLAtGKLLRTLTG--HTGAvrsVAFSPD-GKTLAS 347
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1887-2272 |
4.43e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 4.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1887 ERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLslekeRLTERGKALHDKEKKLLKGKEQLQDIK 1966
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEL-----EKLEKLLQLLPLYQELEALEAELAELP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1967 GKLETYREKLINLSKKLMEEKtvfvAKKEKLTVTEKKIEMedmllAEKQGKLAVEK--VKLAKEITEVIQNSQLIREETE 2044
Cdd:COG4717 146 ERLEELEERLEELRELEEELE----ELEAELAELQEELEE-----LLEQLSLATEEelQDLAEELEELQQRLAELEEELE 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2045 IIK-EAEELTSEMKRVaREKMELVGELEEPPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRLLATEEKDAAR 2123
Cdd:COG4717 217 EAQeELEELEEELEQL-ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAR 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2124 GHLELTREQRICAHEERKLAKATRKLDREKGVSKKPAESRKTLkvLINLISKVRKVTQKESKMTKMNRSLLIKEAELSME 2203
Cdd:COG4717 296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEE--LLELLDRIEELQELLREAEELEEELQLEELEQEIA 373
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2482565915 2204 EKrLDIKELEDTEEQPEIIMEERKLAKMERRLARQMRRLSTEEKRMAEEEGQFDWESKQDSEEEVEEEE 2272
Cdd:COG4717 374 AL-LAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEEL 441
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1733-1994 |
4.57e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 46.10 E-value: 4.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1733 QQEEILSREAEFLAQKKKKLARKLEKM----AHEKEKIAKKINKVEEV--KAVLAQKTETMMEKEKNLA---SEEKKVRE 1803
Cdd:PRK04863 786 KRIEQLRAEREELAERYATLSFDVQKLqrlhQAFSRFIGSHLAVAFEAdpEAELRQLNRRRVELERALAdheSQEQQQRS 865
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1804 EAKN--------QELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLA----------------Q 1859
Cdd:PRK04863 866 QLEQakeglsalNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSvlqsdpeqfeqlkqdyQ 945
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1860 EAKHQMEEEKRLA---------------------LEKD--------RRPEEVKHLQER-REKLREQKQRLAQEKERIAQR 1909
Cdd:PRK04863 946 QAQQTQRDAKQQAfaltevvqrrahfsyedaaemLAKNsdlneklrQRLEQAEQERTRaREQLRQAQAQLAQYNQVLASL 1025
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1910 KTELKVKKTRLAQMEESLSQ--------ERHKLSLEKERLTERgkaLHDKEKKLLKGKEQLQDIKGKLETYREKLINLSK 1981
Cdd:PRK04863 1026 KSSYDAKRQMLQELKQELQDlgvpadsgAEERARARRDELHAR---LSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLER 1102
|
330
....*....|...
gi 2482565915 1982 KLMEEKTVFVAKK 1994
Cdd:PRK04863 1103 DYHEMREQVVNAK 1115
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
119-311 |
4.82e-04 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 45.02 E-value: 4.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 119 HLIVAYCGDMILRLFgdHFKAFKPTGTVPCRFD-ISCLCFNPETKMLLSGILGGVVT-WNIEqTGKGLRMLQISpisgDE 196
Cdd:cd00200 106 RILSSSSRDKTIKVW--DVETGKCLTTLRGHTDwVNSVAFSPDGTFVASSSQDGTIKlWDLR-TGKCVATLTGH----TG 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 197 VVQNIALNgPNGCILALC--ESTLRVLEHQgqgqleeSKRFVATN--CCSPITCCFTSLEENLLYAGNKVGEVYVWTFPQ 272
Cdd:cd00200 179 EVNSVAFS-PDGEKLLSSssDGTIKLWDLS-------TGKCLGTLrgHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRT 250
|
170 180 190
....*....|....*....|....*....|....*....
gi 2482565915 273 SQSLHSFRAHPTVVVCIQSRAEPHTLLTAGKEGIIKEWN 311
Cdd:cd00200 251 GECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1766-1920 |
4.85e-04 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 45.97 E-value: 4.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1766 IAKKI----NKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEee 1841
Cdd:PRK00409 493 IAKRLglpeNIIEEAKKLIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEE-- 570
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2482565915 1842 mlalyeknlsLEEEmlAQEAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRL 1920
Cdd:PRK00409 571 ----------AEKE--AQQAIKEAKKEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEEL 637
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1723-1894 |
5.25e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.78 E-value: 5.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1723 TLGEKETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKiakkiNKVEEVKAVLAQKTETMMEKEKNLASEEKKVR 1802
Cdd:TIGR04523 514 DLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKK-----ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ 588
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1803 EEAKNQELDGQELaLKEDELYEE-AEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLaleKDRRPEE 1881
Cdd:TIGR04523 589 ELIDQKEKEKKDL-IKEIEEKEKkISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEI---RNKWPEI 664
|
170
....*....|...
gi 2482565915 1882 VKHLQERREKLRE 1894
Cdd:TIGR04523 665 IKKIKESKTKIDD 677
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1890-2165 |
5.25e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.14 E-value: 5.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1890 EKLREQKQRLAQEKERIAQRKTELKvkktRLAQMEESLSQERHKLSLEKERLTERGKALHDkekkllkgkeQLQDIKGKL 1969
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELA----ALKKEEKALLKQLAALERRIAALARRIRALEQ----------ELAALEAEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1970 ETYREKLINLSKKLMEEKTvfvakkekltvtekkiEMEDML-LAEKQGKLAVEKVKL-AKEITEVIQNSQLIREETEIIK 2047
Cdd:COG4942 86 AELEKEIAELRAELEAQKE----------------ELAELLrALYRLGRQPPLALLLsPEDFLDAVRRLQYLKYLAPARR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2048 E-AEELTSEMKRVAREKMELVGELEEpPKTEIKEAILRRRRLAMHEVDLMKKRVSIEEKILAYEDRLlatEEKDAARGHL 2126
Cdd:COG4942 150 EqAEELRADLAELAALRAELEAERAE-LEALLAELEEERAALEALKAERQKLLARLEKELAELAAEL---AELQQEAEEL 225
|
250 260 270
....*....|....*....|....*....|....*....
gi 2482565915 2127 ELTREQRICAHEERKLAKATRKLDREKGVSKKPAESRKT 2165
Cdd:COG4942 226 EALIARLEAEAAAAAERTPAAGFAALKGKLPWPVSGRVV 264
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
1795-1940 |
5.69e-04 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 45.22 E-value: 5.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1795 ASEEKKVREEAKNQELDGQElalKEDELYEEAEKLEDKREAlakEEEMLAlyeknlSLEEEMLAQEAKHQMEEEKRLALE 1874
Cdd:TIGR02794 49 AQQANRIQQQKKPAAKKEQE---RQKKLEQQAEEAEKQRAA---EQARQK------ELEQRAAAEKAAKQAEQAAKQAEE 116
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2482565915 1875 KDRRPEEVKHLQERREKLREQKQRLAQEKERiAQRKTELKVKKTrlAQMEESLSQERHKLSLEKER 1940
Cdd:TIGR02794 117 KQKQAEEAKAKQAAEAKAKAEAEAERKAKEE-AAKQAEEEAKAK--AAAEAKKKAEEAKKKAEAEA 179
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
1731-1886 |
6.03e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 45.47 E-value: 6.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1731 LSQQEEILSREAEFLAQKKKKLARklekmahEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEaKNQEL 1810
Cdd:PRK12705 24 LLKKRQRLAKEAERILQEAQKEAE-------EKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKE-EQLDA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1811 DGQELALKEDELYEEAEKLEDKREALAKEEEMLA--LYEK-NLSLEE------EMLAQEAKHQ-------MEEEKRLALE 1874
Cdd:PRK12705 96 RAEKLDNLENQLEEREKALSARELELEELEKQLDneLYRVaGLTPEQarklllKLLDAELEEEkaqrvkkIEEEADLEAE 175
|
170
....*....|..
gi 2482565915 1875 KDRRPEEVKHLQ 1886
Cdd:PRK12705 176 RKAQNILAQAMQ 187
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
1691-2255 |
6.26e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 45.58 E-value: 6.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1691 QEERRLAQEEGKLAHEYVKSATKGGKLAHIEMTLGEKETFLSQQE-EILSREAEFL------------AQKKKKLAR--- 1754
Cdd:pfam10174 80 QDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEhERQAKELFLLrktleemelrieTQKQTLGARdes 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1755 --KLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEK---KVREEAKnqeldgqelalKEDELYEEAEKL 1829
Cdd:pfam10174 160 ikKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKeniHLREELH-----------RRNQLQPDPAKT 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1830 EDKREALAKEEEMLALYEKN---LSLEEEMLAQEAKHQMEEekrlalekdrRPEEVKHLQERREKLREQKQRLAQEKERI 1906
Cdd:pfam10174 229 KALQTVIEMKDTKISSLERNirdLEDEVQMLKTNGLLHTED----------REEEIKQMEVYKSHSKFMKNKIDQLKQEL 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1907 AQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLT---ERGKALH---DKEKKLLKGKEQLQDIKGK-LETYREKLINL 1979
Cdd:pfam10174 299 SKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTakeQRAAILQtevDALRLRLEEKESFLNKKTKqLQDLTEEKSTL 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1980 SKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLA--VEKVKLAKEITEVIQNSQLIREETEIIKE--AEELTSE 2055
Cdd:pfam10174 379 AGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAglKERVKSLQTDSSNTDTALTTLEEALSEKEriIERLKEQ 458
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2056 MKRVAREKMElvgELEEPpKTEIKEAilrRRRLAMHEVDLMKKRVSIEEkiLAYEDRLLATE--EKDAARGHLELTREQR 2133
Cdd:pfam10174 459 REREDRERLE---ELESL-KKENKDL---KEKVSALQPELTEKESSLID--LKEHASSLASSglKKDSKLKSLEIAVEQK 529
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2134 I--CAHEERKLAKATrklDREKGVSKKPAESRKtLKVLINLISKVRKVTQKeskmtkmnrslliKEAELsmeEKRLDIke 2211
Cdd:pfam10174 530 KeeCSKLENQLKKAH---NAEEAVRTNPEINDR-IRLLEQEVARYKEESGK-------------AQAEV---ERLLGI-- 587
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 2212 LEDTEEqpEIIMEERKLAKMERRLARQMRRLST----------EEKRMAEEEGQ 2255
Cdd:pfam10174 588 LREVEN--EKNDKDKKIAELESLTLRQMKEQNKkvanikhgqqEMKKKGAQLLE 639
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
1744-2051 |
6.42e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 45.30 E-value: 6.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1744 FLAQKKKKLARKLEK--MAH----EKEKIAKKINKVEEvkavLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELAL 1817
Cdd:PRK05771 13 TLKSYKDEVLEALHElgVVHiedlKEELSNERLRKLRS----LLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELI 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1818 KE-----DELYEEAEKLEDKREALakeEEMLALYE---------KNLSLEEEMLAqeakhqmeEEKRLALEKDRRPEEvk 1883
Cdd:PRK05771 89 KDveeelEKIEKEIKELEEEISEL---ENEIKELEqeierlepwGNFDLDLSLLL--------GFKYVSVFVGTVPED-- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1884 hlqerreKLREQKQRLAQEKEriaqrkTELKVKKTR-------LAQMEESLSQERHKLSLEKERLTERGKAlhdkEKKLL 1956
Cdd:PRK05771 156 -------KLEELKLESDVENV------EYISTDKGYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTP----SELIR 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1957 KGKEQLQDIKGKLETYREKLINLSKKLMEEKtvfVAKKEKLTVTEKKIEMEDMLLAEK-----QGKLAVEKVKLAKEITE 2031
Cdd:PRK05771 219 EIKEELEEIEKERESLLEELKELAKKYLEEL---LALYEYLEIELERAEALSKFLKTDktfaiEGWVPEDRVKKLKELID 295
|
330 340
....*....|....*....|
gi 2482565915 2032 VIQNSQLIREETEIIKEAEE 2051
Cdd:PRK05771 296 KATGGSAYVEFVEPDEEEEE 315
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1731-1910 |
6.42e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.68 E-value: 6.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1731 LSQQEEILSR-EAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKtetmmekeknlaseekkvREEAKNQ- 1808
Cdd:COG4913 271 LAELEYLRAAlRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREE------------------LDELEAQi 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1809 -ELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEML------AQEAKHQMEEEKRLALEKDRRpee 1881
Cdd:COG4913 333 rGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFaalraeAAALLEALEEELEALEEALAE--- 409
|
170 180
....*....|....*....|....*....
gi 2482565915 1882 vkhLQERREKLREQKQRLAQEKERIAQRK 1910
Cdd:COG4913 410 ---AEAALRDLRRELRELEAEIASLERRK 435
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
1650-1862 |
6.65e-04 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 44.84 E-value: 6.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1650 KERRQIRMAQKQARADwrqarGERRRAREKKLLAHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAhiemtlgeket 1729
Cdd:TIGR02794 72 KLEQQAEEAEKQRAAE-----QARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAK----------- 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1730 flsqqeeilsREAEFLAQKKKKLARKLEKMAHEKEK-IAKKinKVEEVKAVLAQKTetmmeKEKNLAsEEKKVREEAKNQ 1808
Cdd:TIGR02794 136 ----------AEAEAERKAKEEAAKQAEEEAKAKAAaEAKK--KAEEAKKKAEAEA-----KAKAEA-EAKAKAEEAKAK 197
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 1809 ELDGQELALKEDELYEEAEKlEDKREALAKEEEMLALYEKNLSLEEEMLAQEAK 1862
Cdd:TIGR02794 198 AEAAKAKAAAEAAAKAEAEA-AAAAAAEAERKADEAELGDIFGLASGSNAEKQG 250
|
|
| FAM184 |
pfam15665 |
Family with sequence similarity 184, A and B; The function of FAM184 is not known. |
1759-1949 |
7.02e-04 |
|
Family with sequence similarity 184, A and B; The function of FAM184 is not known.
Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 43.50 E-value: 7.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1759 MAHEKEKIAKKINKVEEvKAVLAQKTETMMEKEknlaSEEKKVREEAKNqELDGQELALKEDELYEEAEKlEDKREALAK 1838
Cdd:pfam15665 31 LAETREKILQYKSKIGE-ELDLKRRIQTLEESL----EQHERMKRQALT-EFEQYKRRVEERELKAEAEH-RQRVVELSR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1839 E-EEMLALYEKNLsleeEMLAQEAKhQMEEEKRLALEkDRRPEEVKHLQERREKLREQKQRLAQEKERIAQrktELKVKK 1917
Cdd:pfam15665 104 EvEEAKRAFEEKL----ESFEQLQA-QFEQEKRKALE-ELRAKHRQEIQELLTTQRAQSASSLAEQEKLEE---LHKAEL 174
|
170 180 190
....*....|....*....|....*....|..
gi 2482565915 1918 TRLAQMEESLSQERHKLSLEKERLTERGKALH 1949
Cdd:pfam15665 175 ESLRKEVEDLRKEKKKLAEEYEQKLSKAQAFY 206
|
|
| COG5644 |
COG5644 |
U3 small nucleolar RNA-associated protein 14 [Function unknown]; |
1852-2228 |
9.10e-04 |
|
U3 small nucleolar RNA-associated protein 14 [Function unknown];
Pssm-ID: 227931 [Multi-domain] Cd Length: 869 Bit Score: 45.08 E-value: 9.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1852 LEEEMLAQEAKHQMEEEkrLALEKdRRPEEVKhlqERREKLREQKQRLAQEkERIAQR------KTELKVKKTR------ 1919
Cdd:COG5644 344 LLDAGLENESALKKQEE--LALNK-LSVEEVA---ERTRQLRFMRELMFRE-ERKAKRvakiksKTYRKIRKNRkekema 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1920 LAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLMEektvfvakKEKLTV 1999
Cdd:COG5644 417 LIPKSEDLENEKSEEARALERMTQRHKNTSSWTRKMLERASHGEGTREAVNEQIRKGDELMQRIHG--------KEIMDG 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2000 TEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETEIIKEAEELTSEMKRVAREKMELVGELEEPPKTEIK 2079
Cdd:COG5644 489 EDVSEFSDSDYDTNEQVSTAFEKIRNEEELKGVLGMKFMRDASNRQMAASKISVADLVKVENGDDIDVGELDEVGGDAIY 568
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2080 EAILRRRRL----AMHEVDLMKKRVSIEEKILAYEDRLLATEEKDAARGHLELTREQRICAHEERKLAKAtRKLDREKGV 2155
Cdd:COG5644 569 ANAGRREVFpvveQRRKLAPRKRKEDFVTPSTSLEKSMDRILHGQKKRAEGAVVFEKPLEATENFNPWLD-RKMRRIKRI 647
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2482565915 2156 SKKPAESRKTLKVLINLISKVRKVTQKESKMTKMNRSLL--IKEAELSME-EKRLDIKE--LEDTEEQPEIIMEERKL 2228
Cdd:COG5644 648 KKKAYRRIRRDKRLKKKMPEEENTQENHLGSEKKRHGGVpdILLKEIEVEdDEKTPILSpgGDEEVEEGLSIKTQEEL 725
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
1747-1910 |
9.22e-04 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 44.41 E-value: 9.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1747 QKKKKLARKLEKmahEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEA 1826
Cdd:PRK09510 68 QQQQKSAKRAEE---QRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAA 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1827 EKLEdkrealAKEEEM-LALYEKNLSLEEEMLAQ-EAKHQMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKE 1904
Cdd:PRK09510 145 AKAK------AEAEAKrAAAAAKKAAAEAKKKAEaEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKK 218
|
....*.
gi 2482565915 1905 RIAQRK 1910
Cdd:PRK09510 219 AAAEAK 224
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
1887-2249 |
9.70e-04 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 44.47 E-value: 9.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1887 ERREKLREQKQRLAQEKERiaqrktelkvkktrLAQMEESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQDIK 1966
Cdd:pfam02029 3 DEEEAARERRRRAREERRR--------------QKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAFLDRT 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1967 GKLETYREKLINLS---KKLMEEKTVFVakKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNsqlireet 2043
Cdd:pfam02029 69 AKREERRQKRLQEAlerQKEFDPTIADE--KESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREK-------- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2044 eiiKEAEELTSEMKRVAREKMElvgelEEPPKTEIKEAILRRRRLAMHEVDL-MKKRVSIEEKILAYEDRLLATEEKDAA 2122
Cdd:pfam02029 139 ---EYQENKWSTEVRQAEEEGE-----EEEDKSEEAEEVPTENFAKEEVKDEkIKKEKKVKYESKVFLDQKRGHPEVKSQ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2123 RGHLELTREQRicAHEERKLAKATRKLDREKGVSKKPAESRktlkvlinLISKVRKVTQKESK-MTKMNRSLLIKEAEL- 2200
Cdd:pfam02029 211 NGEEEVTKLKV--TTKRRQGGLSQSQEREEEAEVFLEAEQK--------LEELRRRRQEKESEeFEKLRQKQQEAELELe 280
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2482565915 2201 ----SMEEKRLDIKELEDTEEQPEiimEERKLAKME--RRLARQM--RRLSTEEKRM 2249
Cdd:pfam02029 281 elkkKREERRKLLEEEEQRRKQEE---AERKLREEEekRRMKEEIerRRAEAAEKRQ 334
|
|
| tape_meas_lam_C |
TIGR01541 |
phage tail tape measure protein, lambda family; This model represents a relatively ... |
1731-1876 |
9.82e-04 |
|
phage tail tape measure protein, lambda family; This model represents a relatively well-conserved region near the C-terminus of the tape measure protein of a lambda and related phage. This protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behavior is attributed to proteins from distantly related or unrelated families in other phage. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 273681 [Multi-domain] Cd Length: 332 Bit Score: 44.06 E-value: 9.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1731 LSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAkkinkVEEVKavlaQKTETMMEKeknLASEEKKVREEAKnQEL 1810
Cdd:TIGR01541 6 LTQQIADRKLKKLNTADEKSLQSRSDEIIALIKLEKL-----LEEAE----QKALEALKK---LAEATASIRAQNK-RQL 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1811 DGQELALKEDELYEEAEKLEDK----REALAKeeemlALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKD 1876
Cdd:TIGR01541 73 DRFGLGDKQRERLDARLQIDRTfrkqQRDLNK-----AMTAKGLAGSDLYKEQLAAIKASLNEALAELHA 137
|
|
| RNase_Y_N |
pfam12072 |
RNase Y N-terminal region; |
1728-1839 |
1.03e-03 |
|
RNase Y N-terminal region;
Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 42.95 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1728 ETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKavlaQKTETMMEKEKNLASEE------KKV 1801
Cdd:pfam12072 84 ERRLLQKEETLDRKDESLEKKEESLEKKEKELEAQQQQLEEKEEELEELI----EEQRQELERISGLTSEEakeillDEV 159
|
90 100 110
....*....|....*....|....*....|....*...
gi 2482565915 1802 REEAKnqeldgQELALKEDELYEEAEKLEDKRealAKE 1839
Cdd:pfam12072 160 EEELR------HEAAVMIKEIEEEAKEEADKK---AKE 188
|
|
| GBP_C |
pfam02841 |
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ... |
1747-1902 |
1.12e-03 |
|
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.
Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 43.82 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1747 QKKKKLARKLEKMAHEKEKIAKKINKveevkavlAQKTETMMEKEKnlasEEKKVREEAKNQELDGQELALKEDELYEEA 1826
Cdd:pfam02841 169 RKGVKAEEVLQEFLQSKEAVEEAILQ--------TDQALTAKEKAI----EAERAKAEAAEAEQELLREKQKEEEQMMEA 236
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2482565915 1827 EKledkrealakeeemlALYEKNLSLEEEMLAQEAKHQMEEEKRLALEKDRRPEEVkhlqeRREKLREQKQRLAQE 1902
Cdd:pfam02841 237 QE---------------RSYQEHVKQLIEKMEAEREQLLAEQERMLEHKLQEQEEL-----LKEGFKTEAESLQKE 292
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
1721-1908 |
1.21e-03 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 44.07 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1721 EMTLGEKETFLSQQEEI--LSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLAseE 1798
Cdd:TIGR02794 54 RIQQQKKPAAKKEQERQkkLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAA--E 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1799 KKVREEAKNQELDGQELALKEdelyEEAEKLEDKREALAKEEEMLALYEKNLSLEEEmlaQEAKHQMEEEKRLALEKDRr 1878
Cdd:TIGR02794 132 AKAKAEAEAERKAKEEAAKQA----EEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAE---AEAKAKAEEAKAKAEAAKA- 203
|
170 180 190
....*....|....*....|....*....|.
gi 2482565915 1879 peevKHLQERREKLREQKQRLAQ-EKERIAQ 1908
Cdd:TIGR02794 204 ----KAAAEAAAKAEAEAAAAAAaEAERKAD 230
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
1749-1896 |
1.22e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 43.85 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1749 KKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLaSEEKKVREEAKNQELDGQELALKED--ELYEEA 1826
Cdd:smart00787 146 KEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQL-KQLEDELEDCDPTELDRAKEKLKKLlqEIMIKV 224
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2482565915 1827 EKLEDKREAL-AKEEEMLALYEKNLSLEEEMlaqeakhqMEEEKRLALEKDRRPEEVKHLQERREKLREQK 1896
Cdd:smart00787 225 KKLEELEEELqELESKIEDLTNKKSELNTEI--------AEAEKKLEQCRGFTFKEIEKLKEQLKLLQSLT 287
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1446-2255 |
1.25e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 44.65 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1446 RKTRKTVKQEKMEKDERIEETISAEELAVTLKPEEVAEEGEGRSKKrkgtweeeegaekrekeeeeeQMIEPKEAITEAV 1525
Cdd:TIGR00606 192 RQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSR---------------------EIVKSYENELDPL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1526 ERKLSWVEwkshwdewqkaqtqrAVLWEDWKKQCDKKHFEEEARLRVEGKLQPSEEVEEPKKMlTWDEWREVWENILHTK 1605
Cdd:TIGR00606 251 KNRLKEIE---------------HNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQG-TDEQLNDLYHNHQRTV 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1606 SEKELDLGEMFKEGEEEEEEEEEEIGeeeeeeeeeiyeeeaegRKERRQIRMAQKQARADWRQARGERRRAREKKLLAHE 1685
Cdd:TIGR00606 315 REKERELVDCQRELEKLNKERRLLNQ-----------------EKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRL 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1686 E----EKLAQEERRLaqeegKLAHEYVKSATKgGKLAHIEMTLGEketfLSQQEEILSREAEFLAQKKKKLARKLEkmaH 1761
Cdd:TIGR00606 378 EldgfERGPFSERQI-----KNFHTLVIERQE-DEAKTAAQLCAD----LQSKERLKQEQADEIRDEKKGLGRTIE---L 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1762 EKEKIAKKINKVEEVKAVLAQKTETM---MEKEKNLASEEKKVREEAKNQELDgqelALKEDELYEEAEKLEDKREALAK 1838
Cdd:TIGR00606 445 KKEILEKKQEELKFVIKELQQLEGSSdriLELDQELRKAERELSKAEKNSLTE----TLKKEVKSLQNEKADLDRKLRKL 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1839 EEEMLAL-YEKNLSLEEEMLaqeAKHQMEEEKRLALEKDRRPEEV----------KHLQERREKLREQKQrlaQEKERIA 1907
Cdd:TIGR00606 521 DQEMEQLnHHTTTRTQMEML---TKDKMDKDEQIRKIKSRHSDELtsllgyfpnkKQLEDWLHSKSKEIN---QTRDRLA 594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1908 QRKTELkvkktrlaqmeESLSQERHKLSLEKERLTERGKALHDKEKKL---LKGKEQLQDIKGKLETYREKLINLSKK-- 1982
Cdd:TIGR00606 595 KLNKEL-----------ASLEQNKNHINNELESKEEQLSSYEDKLFDVcgsQDEESDLERLKEEIEKSSKQRAMLAGAta 663
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1983 ----LMEEKT------------VFVAKKEkLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQNSQLIREETE-I 2045
Cdd:TIGR00606 664 vysqFITQLTdenqsccpvcqrVFQTEAE-LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDlK 742
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2046 IKEAEELTSEMKRVAREKMELVGELEEPPKT-EIKEAILRRRRLAMHEVDLMKK-RVSIEEKILAYEDRLLATEEKDAAR 2123
Cdd:TIGR00606 743 EKEIPELRNKLQKVNRDIQRLKNDIEEQETLlGTIMPEEESAKVCLTDVTIMERfQMELKDVERKIAQQAAKLQGSDLDR 822
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2124 GHLELTREQRICAHEERKLakaTRKLDREKGVSKKPAESRKTLKVLINLISkvrkvTQKESKMTKMNRSLLIKE--AELS 2201
Cdd:TIGR00606 823 TVQQVNQEKQEKQHELDTV---VSKIELNRKLIQDQQEQIQHLKSKTNELK-----SEKLQIGTNLQRRQQFEEqlVELS 894
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*.
gi 2482565915 2202 MEEKRLdIKELEDTEEQ--PEIIMEERKLAKMERRLARQmrrlsTEEKRMAEEEGQ 2255
Cdd:TIGR00606 895 TEVQSL-IREIKDAKEQdsPLETFLEKDQQEKEELISSK-----ETSNKKAQDKVN 944
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1518-1925 |
1.39e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1518 KEAITEAVERKLSWVEWKSHWDEWQKAQTQRAVLwedwkkqcdkKHFEEEARlRVEGKLQPSEEVEEPKKML--TWDEWR 1595
Cdd:COG4717 108 EAELEELREELEKLEKLLQLLPLYQELEALEAEL----------AELPERLE-ELEERLEELRELEEELEELeaELAELQ 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1596 EVWENILHTKSEKELDLGEMFKEGEEEEeeeeeeigeeeeeeeeeiyeeeaegRKERRQIRMAQKQARADWRQARGERRR 1675
Cdd:COG4717 177 EELEELLEQLSLATEEELQDLAEELEEL-------------------------QQRLAELEEELEEAQEELEELEEELEQ 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1676 AREKKLLAHEEEKLAQEERRLAQE------EGKLAHEYVKSATKGGK------LAHIEMTLGEKETFLSQQE----EILS 1739
Cdd:COG4717 232 LENELEAAALEERLKEARLLLLIAaallalLGLGGSLLSLILTIAGVlflvlgLLALLFLLLAREKASLGKEaeelQALP 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1740 REAEFLAQKKKKLARKLE-KMAHEKEKIAKKINKVEEVKAVLAQKTEtmmekeknLASEEKKVREEAKNQELDGQELALK 1818
Cdd:COG4717 312 ALEELEEEELEELLAALGlPPDLSPEELLELLDRIEELQELLREAEE--------LEEELQLEELEQEIAALLAEAGVED 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1819 EDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEE-KRLALEKDRRPEEVKHLQERREKLREQKQ 1897
Cdd:COG4717 384 EEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEElEELEEELEELEEELEELREELAELEAELE 463
|
410 420
....*....|....*....|....*...
gi 2482565915 1898 RLAqEKERIAQRKTELKVKKTRLAQMEE 1925
Cdd:COG4717 464 QLE-EDGELAELLQELEELKAELRELAE 490
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1649-1931 |
1.41e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1649 RKERRQIRMAQKQARADWRQARGERRRAREKKLLAHEEEKLAQEERRLAQE------EGKLAHEYVKSATKGGK------ 1716
Cdd:COG4717 205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAaallalLGLGGSLLSLILTIAGVlflvlg 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1717 LAHIEMTLGEKETFLSQQE----EILSREAEFLAQKKKKLARKLE-KMAHEKEKIAKKINKVEEVKAVLAQKTEtmmeke 1791
Cdd:COG4717 285 LLALLFLLLAREKASLGKEaeelQALPALEELEEEELEELLAALGlPPDLSPEELLELLDRIEELQELLREAEE------ 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1792 knLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEE-KR 1870
Cdd:COG4717 359 --LEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEElEE 436
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2482565915 1871 LALEKDRRPEEVKHLQERR----------------EKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQER 1931
Cdd:COG4717 437 LEEELEELEEELEELREELaeleaeleqleedgelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| PRK00106 |
PRK00106 |
ribonuclease Y; |
1781-1930 |
1.77e-03 |
|
ribonuclease Y;
Pssm-ID: 178867 [Multi-domain] Cd Length: 535 Bit Score: 43.70 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1781 AQKTETMMEKEKnlasEEKKVREEAKNQ-ELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSleeemlaq 1859
Cdd:PRK00106 68 ALKKELLLEAKE----EARKYREEIEQEfKSERQELKQIESRLTERATSLDRKDENLSSKEKTLESKEQSLT-------- 135
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2482565915 1860 eakhqmeeekrlalekdrrpEEVKHLQERREKLREQKQRLAQEKERIAQRkTELKVKKTRLAQMEESLSQE 1930
Cdd:PRK00106 136 --------------------DKSKHIDEREEQVEKLEEQKKAELERVAAL-SQAEAREIILAETENKLTHE 185
|
|
| YqiK |
COG2268 |
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]; |
1763-1912 |
2.05e-03 |
|
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 43.32 E-value: 2.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1763 KEKIAKKInKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDG----QELALKEDELYEEAEKLEDKREALAK 1838
Cdd:COG2268 191 RRKIAEII-RDARIAEAEAERETEIAIAQANREAEEAELEQEREIETARIaeaeAELAKKKAEERREAETARAEAEAAYE 269
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 1839 EEEMlalyeknlsleeemlaqeakhQMEEEKRLALEKDRRPEEVKhLQERREKLREQKQRlAQEKERIAQRKTE 1912
Cdd:COG2268 270 IAEA---------------------NAEREVQRQLEIAEREREIE-LQEKEAEREEAELE-ADVRKPAEAEKQA 320
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
1689-1840 |
2.69e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 43.16 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1689 LAQEERRLAQEEGKLAHEYVKSATKGGKLAHIEmTLGEKETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAK 1768
Cdd:PRK12705 24 LLKKRQRLAKEAERILQEAQKEAEEKLEAALLE-AKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDN 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2482565915 1769 KINKVEEVKAVLAQKTETMMEKEKNLASEEKKV---REEAKNQELdgqeLALKEDELYEEAEKLEDKREALAKEE 1840
Cdd:PRK12705 103 LENQLEEREKALSARELELEELEKQLDNELYRVaglTPEQARKLL----LKLLDAELEEEKAQRVKKIEEEADLE 173
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
1780-1935 |
2.89e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.40 E-value: 2.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1780 LAQKTETMmekEKNLASEEKKVREEAKNQELdGQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQ 1859
Cdd:COG3096 510 LAQRLQQL---RAQLAELEQRLRQQQNAERL-LEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQ 585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1860 EAKHQMEEEKRLAlekDRRPEEVKhLQERREKLREQ-------KQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERH 1932
Cdd:COG3096 586 QLEQLRARIKELA---ARAPAWLA-AQDALERLREQsgealadSQEVTAAMQQLLEREREATVERDELAARKQALESQIE 661
|
...
gi 2482565915 1933 KLS 1935
Cdd:COG3096 662 RLS 664
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1384-2152 |
3.65e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.12 E-value: 3.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1384 EEATREEVTGQEEMPEAGKQRLEKEEGLqeaeeetQEKDKEKEVAFLESEDVvkgkrrprkgrKTRKTVKQEKMEKDERI 1463
Cdd:TIGR02168 256 EELTAELQELEEKLEELRLEVSELEEEI-------EELQKELYALANEISRL-----------EQQKQILRERLANLERQ 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1464 EETISAEELAVTLKPEEVAEEGEGRSKKrkgtweeeegaekreKEEEEEQMIEPKEAITEAVERklsWVEWKSHWDEWQK 1543
Cdd:TIGR02168 318 LEELEAQLEELESKLDELAEELAELEEK---------------LEELKEELESLEAELEELEAE---LEELESRLEELEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1544 AQTQRAvlwedwKKQCDKKHFEEEARLRVEgklQPSEEVEEPKKMLtwDEWREVWENILHTKSEKELDLGEMFKEGEEEE 1623
Cdd:TIGR02168 380 QLETLR------SKVAQLELQIASLNNEIE---RLEARLERLEDRR--ERLQQEIEELLKKLEEAELKELQAELEELEEE 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1624 EEEEEEIGEEEEEEEEEIYEEEAEGRKERRQIR--MAQKQARADWRQARGERRRAREK--KLLAHEEEKLAQEERRLAQ- 1698
Cdd:TIGR02168 449 LEELQEELERLEEALEELREELEEAEQALDAAEreLAQLQARLDSLERLQENLEGFSEgvKALLKNQSGLSGILGVLSEl 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1699 ---------------------------EEGKLAHEYVKSAtKGGKLAHIEMTLGEKETFLSQQEEILSREAEFLAqkkkk 1751
Cdd:TIGR02168 529 isvdegyeaaieaalggrlqavvvenlNAAKKAIAFLKQN-ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG----- 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1752 LARKLEKMAHEKEK--------------------IAKKINKvEEVKAVL---------------AQKTETMMEKEKNLAS 1796
Cdd:TIGR02168 603 VAKDLVKFDPKLRKalsyllggvlvvddldnaleLAKKLRP-GYRIVTLdgdlvrpggvitggsAKTNSSILERRREIEE 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1797 EEKKVRE-EAKNQELDgQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEE-------EMLAQEAKHQMEEE 1868
Cdd:TIGR02168 682 LEEKIEElEEKIAELE-KALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEaeveqleERIAQLSKELTELE 760
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1869 KRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKAL 1948
Cdd:TIGR02168 761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1949 HDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLME--------EKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAV 2020
Cdd:TIGR02168 841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEAllneraslEEALALLRSELEELSEELRELESKRSELRRELEEL 920
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2021 EKvKLAKEITEVIQNSQLIREETEIIKEAEELTSEMkrvAREKMELVGELEEPPKTEIKEaiLRRRRLAMHEVDLMkkrv 2100
Cdd:TIGR02168 921 RE-KLAQLELRLEGLEVRIDNLQERLSEEYSLTLEE---AEALENKIEDDEEEARRRLKR--LENKIKELGPVNLA---- 990
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|..
gi 2482565915 2101 SIEEkilaYEDrllATEEKDaarghlELTREQRICAHEERKLAKATRKLDRE 2152
Cdd:TIGR02168 991 AIEE----YEE---LKERYD------FLTAQKEDLTEAKETLEEAIEEIDRE 1029
|
|
| DDRGK |
pfam09756 |
DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and ... |
1768-1872 |
3.73e-03 |
|
DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.
Pssm-ID: 370664 [Multi-domain] Cd Length: 188 Bit Score: 41.18 E-value: 3.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1768 KKINKVEEVKAVLAQKTETMMEKEKNLaSEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEEEMLALYE 1847
Cdd:pfam09756 1 KKLGAKKRAKLELKEAKRQQREAEEEE-REEREKLEEKREEEYKEREEREEEAEKEKEEEERKQEEEQERKEQEEYEKLK 79
|
90 100
....*....|....*....|....*
gi 2482565915 1848 KNLSLEEEmlAQEAKHQMEEEKRLA 1872
Cdd:pfam09756 80 SQFVVEEE--GTDKLSAEDESQLLE 102
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1650-2253 |
3.87e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.12 E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1650 KERRQIRMAQKQARADWRQARGERRRARekKLLAHEEEKLAQEERRLAQEEGKLAHEYVKSATKGGKLAHiEMTLGEKET 1729
Cdd:TIGR02168 361 EELEAELEELESRLEELEEQLETLRSKV--AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK-KLEEAELKE 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1730 fLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQE 1809
Cdd:TIGR02168 438 -LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQS 516
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1810 LDGQELALKEDeLYEEAEKLEDKREAlAKEEEMLALYEKNlsLEEEMLAQEAKHQMEEEKRLALEKDRRPEevKHLQ-ER 1888
Cdd:TIGR02168 517 GLSGILGVLSE-LISVDEGYEAAIEA-ALGGRLQAVVVEN--LNAAKKAIAFLKQNELGRVTFLPLDSIKG--TEIQgND 590
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1889 REKLREQKQRLAQEKERIaqrKTELKVKK------------TRLAQMEESLSQERHKL---SLEKERLTERG-------- 1945
Cdd:TIGR02168 591 REILKNIEGFLGVAKDLV---KFDPKLRKalsyllggvlvvDDLDNALELAKKLRPGYrivTLDGDLVRPGGvitggsak 667
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1946 ----------------KALHDKEKKLLKGKEQLQDIKGKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEmedm 2009
Cdd:TIGR02168 668 tnssilerrreieeleEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE---- 743
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2010 LLAEKQGKLAVEKVKLAKEITEviqNSQLIREETEIIKEAEELTSEMKRVAREKMELVGELEEppKTEIKEAILRRRRLA 2089
Cdd:TIGR02168 744 QLEERIAQLSKELTELEAEIEE---LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE--ALDELRAELTLLNEE 818
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2090 MHEVDLmkKRVSIEEKILAYEDRLLATEE-KDAARGHLELTREQRicAHEERKLAKATRKLDREKGVSKKPAESRKTLKV 2168
Cdd:TIGR02168 819 AANLRE--RLESLERRIAATERRLEDLEEqIEELSEDIESLAAEI--EELEELIEELESELEALLNERASLEEALALLRS 894
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2169 -LINLISKVRKVtqkESKMTKMNRSL-----LIKEAELSMEEKRLDIKELEDT------EEQPEIIMEERKLAKMERRLA 2236
Cdd:TIGR02168 895 eLEELSEELREL---ESKRSELRRELeelreKLAQLELRLEGLEVRIDNLQERlseeysLTLEEAEALENKIEDDEEEAR 971
|
650 660
....*....|....*....|...
gi 2482565915 2237 RQMRRLSTEEKR------MAEEE 2253
Cdd:TIGR02168 972 RRLKRLENKIKElgpvnlAAIEE 994
|
|
| COG5644 |
COG5644 |
U3 small nucleolar RNA-associated protein 14 [Function unknown]; |
1685-1925 |
3.99e-03 |
|
U3 small nucleolar RNA-associated protein 14 [Function unknown];
Pssm-ID: 227931 [Multi-domain] Cd Length: 869 Bit Score: 42.77 E-value: 3.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1685 EEEKLAQEERRLAQEE---GKLAHEYVKSATKggklahiEMTLGEKETFlsqQEEilsREAEFLAQKKKKLARKLEKMAH 1761
Cdd:COG5644 345 LDAGLENESALKKQEElalNKLSVEEVAERTR-------QLRFMRELMF---REE---RKAKRVAKIKSKTYRKIRKNRK 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1762 EKEK-IAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQE-------------------------LDGQEL 1815
Cdd:COG5644 412 EKEMaLIPKSEDLENEKSEEARALERMTQRHKNTSSWTRKMLERASHGEgtreavneqirkgdelmqrihgkeiMDGEDV 491
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1816 ALKEDELYEEAEKLEDKREALAKEEEMLAL----YEKNLSLEEEMLAQEAKHQM---EEEKRLAL-EKDRRPEEVKHLQE 1887
Cdd:COG5644 492 SEFSDSDYDTNEQVSTAFEKIRNEEELKGVlgmkFMRDASNRQMAASKISVADLvkvENGDDIDVgELDEVGGDAIYANA 571
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2482565915 1888 RREKLR---EQKQRLAQEKeRIAQRKTELKVKKTRLAQMEE 1925
Cdd:COG5644 572 GRREVFpvvEQRRKLAPRK-RKEDFVTPSTSLEKSMDRILH 611
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1638-2133 |
4.16e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 42.72 E-value: 4.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1638 EEEIYEEEAEGRKERRQIRMAQKqaradwrqargerrrarekkllahEEEKLAQEERRLAQEEGKLAHEyvksatKGGKL 1717
Cdd:PRK02224 250 REELETLEAEIEDLRETIAETER------------------------EREELAEEVRDLRERLEELEEE------RDDLL 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1718 AHIEMTLGEKETFLSQQEEILSREAEF---LAQKKKKLARKLEkmahEKEKIAKKINKVEEVKAVLAQKTETMmekEKNL 1794
Cdd:PRK02224 300 AEAGLDDADAEAVEARREELEDRDEELrdrLEECRVAAQAHNE----EAESLREDADDLEERAEELREEAAEL---ESEL 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1795 ASEEKKVRE-EAKNQELDGQELALKE--DELYEEAEKLEDKREALAKEEEmlALYEKNLSLEEEMlaQEAKHQMEEEKRL 1871
Cdd:PRK02224 373 EEAREAVEDrREEIEELEEEIEELRErfGDAPVDLGNAEDFLEELREERD--ELREREAELEATL--RTARERVEEAEAL 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1872 aLEKDRRPE---------EVKHLQERREKLREQKQRLAQEKERIAQRktelkvkKTRLAQMEESLSQERhklslEKERLT 1942
Cdd:PRK02224 449 -LEAGKCPEcgqpvegspHVETIEEDRERVEELEAELEDLEEEVEEV-------EERLERAEDLVEAED-----RIERLE 515
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1943 ERGKALHDKekkllkgkeqLQDIKGKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAvek 2022
Cdd:PRK02224 516 ERREDLEEL----------IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLA--- 582
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2023 vklakEITEVIQNSQLIREETEIIKEAEELTSEMkrvaREKMELVGELEEPPKTEIKEAILRRRRLAmHEVDlmkkRVSI 2102
Cdd:PRK02224 583 -----ELKERIESLERIRTLLAAIADAEDEIERL----REKREALAELNDERRERLAEKRERKRELE-AEFD----EARI 648
|
490 500 510
....*....|....*....|....*....|.
gi 2482565915 2103 EEkilAYEDRLLATEEKDAARGHLELTREQR 2133
Cdd:PRK02224 649 EE---AREDKERAEEYLEQVEEKLDELREER 676
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1885-2073 |
4.30e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 4.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1885 LQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSlEKERltergkalhdkekkllkgkeQLQD 1964
Cdd:COG1579 12 LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIK-RLEL--------------------EIEE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1965 IKGKLETYREKLINLS-----KKLMEEKTvfvAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEviqnsqLI 2039
Cdd:COG1579 71 VEARIKKYEEQLGNVRnnkeyEALQKEIE---SLKRRISDLEDEILELMERIEELEEELAELEAELAELEAE------LE 141
|
170 180 190
....*....|....*....|....*....|....
gi 2482565915 2040 REETEIIKEAEELTSEMKRVAREKMELVGELEEP 2073
Cdd:COG1579 142 EKKAELDEELAELEAELEELEAEREELAAKIPPE 175
|
|
| Tropomyosin |
pfam00261 |
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ... |
1764-1983 |
4.55e-03 |
|
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.
Pssm-ID: 459736 [Multi-domain] Cd Length: 235 Bit Score: 41.55 E-value: 4.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1764 EKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVREEAKNQELDGQELALKEDELYEEAEKLEDKREALAKEEEML 1843
Cdd:pfam00261 1 KKMQQIKEELDEAEERLKEAMKKLEEAEKRAEKAEAEVAALNRRIQLLEEELERTEERLAEALEKLEEAEKAADESERGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1844 -ALYEKNLSLEEEMLAQEAkhQMEEEKRLALEKDRRPEEVkhlqERREKLREQKQRLAQEKERIAQRK-----TELKVKK 1917
Cdd:pfam00261 81 kVLENRALKDEEKMEILEA--QLKEAKEIAEEADRKYEEV----ARKLVVVEGDLERAEERAELAESKiveleEELKVVG 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2482565915 1918 TRLAQME---ESLSQERHKLSLEKERLTERGKALHDKEKKLLKGKEQLQ----DIKGKLETYREKLINLSKKL 1983
Cdd:pfam00261 155 NNLKSLEaseEKASEREDKYEEQIRFLTEKLKEAETRAEFAERSVQKLEkevdRLEDELEAEKEKYKAISEEL 227
|
|
| PspA |
COG1842 |
Phage shock protein A [Transcription, Signal transduction mechanisms]; |
1765-1929 |
4.62e-03 |
|
Phage shock protein A [Transcription, Signal transduction mechanisms];
Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 41.35 E-value: 4.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1765 KIAKKINKVEEVKAVLAQKTETMmekEKNLAseekKVREEAKNQELDGQELALKEDELYEEAEKLEDK-REALAKEEEML 1843
Cdd:COG1842 13 NINALLDKAEDPEKMLDQAIRDM---EEDLV----EARQALAQVIANQKRLERQLEELEAEAEKWEEKaRLALEKGREDL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1844 AlyeknlsleEEMLAQEAKHqmeEEKRLALEkdrrpEEVKHLQERREKLREQKQRLaqeKERIAQRKTELKVKKTRL--A 1921
Cdd:COG1842 86 A---------REALERKAEL---EAQAEALE-----AQLAQLEEQVEKLKEALRQL---ESKLEELKAKKDTLKARAkaA 145
|
....*...
gi 2482565915 1922 QMEESLSQ 1929
Cdd:COG1842 146 KAQEKVNE 153
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1874-2081 |
4.65e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.12 E-value: 4.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1874 EKDRRPEEVKHLQERREKLREQKQRLAQE----KERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALH 1949
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAEleelNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1950 DKEKKLLKGKE-----QLQDIKGKLEtYREKLINLSKKLMEEktvFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVK 2024
Cdd:COG3883 97 RSGGSVSYLDVllgseSFSDFLDRLS-ALSKIADADADLLEE---LKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2482565915 2025 LAKEITEviQNSQLIREETEIIKEAEELTSEMKRVAREKMELVGELEEPPKTEIKEA 2081
Cdd:COG3883 173 LEAQQAE--QEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAA 227
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
1726-2257 |
4.81e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 42.58 E-value: 4.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1726 EKETFLSQQEEI--LSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKavlaqktetmmekeKNLASEEKKVRE 1803
Cdd:PRK01156 150 QRKKILDEILEInsLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIK--------------KQIADDEKSHSI 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1804 EAKNQELDGQELALKEDELYEEAEKLedkrealakeEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRL---ALEKDRRPE 1880
Cdd:PRK01156 216 TLKEIERLSIEYNNAMDDYNNLKSAL----------NELSSLEDMKNRYESEIKTAESDLSMELEKNNyykELEERHMKI 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1881 EVKHLQERREKLRE---QKQRLAQEKERIAQRKTELKVKKTRLAQME--ESLSQERHKLSLEKERLTERGKALHDKEKKL 1955
Cdd:PRK01156 286 INDPVYKNRNYINDyfkYKNDIENKKQILSNIDAEINKYHAIIKKLSvlQKDYNDYIKKKSRYDDLNNQILELEGYEMDY 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1956 LKGKEQLQDIKGKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMEDMLLAEKQGKLAVEKVKLAKEITEVIQN 2035
Cdd:PRK01156 366 NSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRN 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2036 SQLI--------------------------REETEIIKEAEELTSEMKRVAREKMELVGELEEPPKTEIKEAILRRRRLA 2089
Cdd:PRK01156 446 MEMLngqsvcpvcgttlgeeksnhiinhynEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIE 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2090 MHEVDL---MKKRVSIEEKILAYEDrlLATEEKDAARGHLELTREQRICAHEERKLAKATRKLDREKGVSKKPAESRKTL 2166
Cdd:PRK01156 526 SARADLediKIKINELKDKHDKYEE--IKNRYKSLKLEDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRL 603
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2167 KVLINLISKVRKVTQKEskmtkmnrsllIKEAELSMEEKRLDIKELEDTEEQPEIIME-----ERKLAKMERRLARQMR- 2240
Cdd:PRK01156 604 QEIEIGFPDDKSYIDKS-----------IREIENEANNLNNKYNEIQENKILIEKLRGkidnyKKQIAEIDSIIPDLKEi 672
|
570
....*....|....*....
gi 2482565915 2241 --RLSTEEKRMAEEEGQFD 2257
Cdd:PRK01156 673 tsRINDIEDNLKKSRKALD 691
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
1961-2256 |
4.81e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 42.76 E-value: 4.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1961 QLQDIKGKLETYREKLINLSKKLMEEKTVFVAKKEKLTVTEKKIEMED-----------MLLAEKQ---GKLAVEKVKLA 2026
Cdd:COG5022 818 CIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKketiylqsaqrVELAERQlqeLKIDVKSISSL 897
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2027 KEiteviQNSQLireeteiIKEAEELTSEMKRVAREKMELVGELEeppkTEIKEAILRRRrlAMHEVDLMKKRVSIEEKI 2106
Cdd:COG5022 898 KL-----VNLEL-------ESEIIELKKSLSSDLIENLEFKTELI----ARLKKLLNNID--LEEGPSIEYVKLPELNKL 959
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 2107 LAYEDRLL-ATEEKDAARGHLELTREQRICAHEE-----RKLAKATRKLDREKGVSKKPAESRKTLKVLINLISKVRKVT 2180
Cdd:COG5022 960 HEVESKLKeTSEEYEDLLKKSTILVREGNKANSElknfkKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSES 1039
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2482565915 2181 QKESKMTKMNrsllikeaelsmEEKRLDIKELEDTEEQPEIIMEERKLAKMERRLARQMRRLSTEEKRMAEEEGQF 2256
Cdd:COG5022 1040 TELSILKPLQ------------KLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINVKDLEV 1103
|
|
| MAP7 |
pfam05672 |
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ... |
1824-1948 |
5.49e-03 |
|
MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.
Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 40.02 E-value: 5.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1824 EEAEKL--EDKREALAK----EEEMLALYEKNLSLEEEML---AQEAKHQMEEEKRLALEKDRRPEEvkHLQERREKLRE 1894
Cdd:pfam05672 10 EEAARIlaEKRRQAREQrereEQERLEKEEEERLRKEELRrraEEERARREEEARRLEEERRREEEE--RQRKAEEEAEE 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 1895 QKQRLAQEKERIAQRKTELKVKKTRLAQmEESLSQERHKLSLEKERLtERGKAL 1948
Cdd:pfam05672 88 REQREQEEQERLQKQKEEAEAKAREEAE-RQRQEREKIMQQEEQERL-ERKKRI 139
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
1777-1917 |
5.84e-03 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 41.75 E-value: 5.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1777 KAVLAQKTETMMEKEKNLASEE---KKVREEAKNQEldgQELALKEDELYEEAEKLEDKREALAKEEemlalyEKNLSLE 1853
Cdd:TIGR02794 46 GAVAQQANRIQQQKKPAAKKEQerqKKLEQQAEEAE---KQRAAEQARQKELEQRAAAEKAAKQAEQ------AAKQAEE 116
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2482565915 1854 EEMLAQEAKHQMEEEKRLALEKDRRP---EEVKHLQERREKLREQKQRLAQEKERIAQRKTELKVKK 1917
Cdd:TIGR02794 117 KQKQAEEAKAKQAAEAKAKAEAEAERkakEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKA 183
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
1745-1904 |
5.95e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.00 E-value: 5.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1745 LAQKKKKLARKLEKMAHEKEKIAkkinkvEEVKAVLAQKTETMMEKEKNlaSEEKKVREEAKNQELDGQELALKEDELYE 1824
Cdd:PRK12705 24 LLKKRQRLAKEAERILQEAQKEA------EEKLEAALLEAKELLLRERN--QQRQEARREREELQREEERLVQKEEQLDA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1825 EAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKH--QMEEEKRLALEKDRRPEEVKHLQERREKLREQKQRLAQE 1902
Cdd:PRK12705 96 RAEKLDNLENQLEEREKALSARELELEELEKQLDNELYRvaGLTPEQARKLLLKLLDAELEEEKAQRVKKIEEEADLEAE 175
|
..
gi 2482565915 1903 KE 1904
Cdd:PRK12705 176 RK 177
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
1736-2057 |
6.15e-03 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 42.51 E-value: 6.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1736 EILSREAEF-LAQKKKKLARKLEKMAHEKEKIAKK----INKVEEVKAVLAQKtETMMEKEKNLASEEKKVREEAKNQEL 1810
Cdd:PTZ00440 1713 EVSNDDVDYnEAKTLREEAQKEEVNLNNKEEEAKKylndIKKQESFRFILYMK-EKLDELSKMCKQQYNIVDEGYNYIKK 1791
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1811 DGQELALKEDE--LYEEAEKLEDKREALAKeeemlalyeknlsLEEEMLAQEAKHQMEEEKRLA------LEKDRRPEEV 1882
Cdd:PTZ00440 1792 KIEYIKTLNDEnnLSDSLNQAEDKNKEVAN-------------LTHYTNKNEAKNLLGHVVKSAnfigikIMTGLQPTEL 1858
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1883 K---HLQERREKLREQKQRLAQEKERIAQRKTELKVKKTRLAQMEESLSQERHKLSLEK-----ERLTERGKALHDKEKK 1954
Cdd:PTZ00440 1859 TpdaSLETAPELTFESENNSDLELDHLSSNKNELDVYKNIQDAYKSSLQILKYSDDIDKkqrdcNKLVEDGNEIYLKSTA 1938
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1955 LLKGKEQLQDIKGKLETYREKLINLSKKLMEEKtvfvakkeKLTVTEKKIEMedMLLAEKQGKLAVEKVKLAKEITEVIQ 2034
Cdd:PTZ00440 1939 INELKNMINSVKNKESAISNKIDNVSNKLSELN--------KITCNDESYDE--ILEKEEYEELKDLRNSFNQEKAETLN 2008
|
330 340
....*....|....*....|....*.
gi 2482565915 2035 NSQL--IREETEI-IKEAEELTSEMK 2057
Cdd:PTZ00440 2009 NLKLnkIKEDFNSyKNLLDELEKSVK 2034
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
601-674 |
6.87e-03 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 41.17 E-value: 6.87e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2482565915 601 TLPLHQCPITSFDVCLSLNVFATGGSDGTVRLWDFQGRlIAMLDSSLHFGPLCFandrgdlLVTFNQSIYLVSC 674
Cdd:cd00200 4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETG-ELLRTLKGHTGPVRD-------VAASADGTYLASG 69
|
|
| PRK14160 |
PRK14160 |
heat shock protein GrpE; Provisional |
1798-1906 |
7.79e-03 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237629 [Multi-domain] Cd Length: 211 Bit Score: 40.51 E-value: 7.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1798 EKKVREEAKNQELDgQELALKEDELYEEAEKLEDKREALAKEEEMLALYEKNLSLEEEMLAQEAKHQMEEEKRLAlekdr 1877
Cdd:PRK14160 1 MEKECKDAKHENME-EDCCKENENKEEDKGKEEDLEFEEIEKEEIIEDSEESNEVKIEELKDENNKLKEENKKLE----- 74
|
90 100 110
....*....|....*....|....*....|...
gi 2482565915 1878 rpEEVKHLQERREKLREQ----KQRLAQEKERI 1906
Cdd:PRK14160 75 --NELEALKDRLLRTVAEydnyRKRTAKEKEGI 105
|
|
| Laminin_I |
pfam06008 |
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from ... |
1723-1896 |
7.88e-03 |
|
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Pssm-ID: 310534 [Multi-domain] Cd Length: 258 Bit Score: 40.86 E-value: 7.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1723 TLGEKETFLSQQEEILSREAEFLAQKKKKLARKLEKMAHEKEKIAKKINKVEEVKAVLAQKTETMMEKEKNLASEEKKVR 1802
Cdd:pfam06008 58 ELQKKATQTLAKAQQVNAESERTLGHAKELAEAIKNLIDNIKEINEKVATLGENDFALPSSDLSRMLAEAQRMLGEIRSR 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1803 EEAKNQELDGQELALKEDeLYEEAEKL----EDKREALAKE-EEMLALYEKNLSLEEEMLaQEAKHQMEEEKRLALEKDR 1877
Cdd:pfam06008 138 DFGTQLQNAEAELKAAQD-LLSRIQTWfqspQEENKALANAlRDSLAEYEAKLSDLRELL-REAAAKTRDANRLNLANQA 215
|
170
....*....|....*....
gi 2482565915 1878 RPEEvkhLQERREKLREQK 1896
Cdd:pfam06008 216 NLRE---FQRKKEEVSEQK 231
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
1689-1909 |
7.89e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 41.34 E-value: 7.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1689 LAQEERRLAQEEGK-------LAHEYVKSATKGGKLAHIEMTLGEKETFLSQQEEILSREAEFLAQK------KKKL-AR 1754
Cdd:pfam15905 78 LEKEIRALVQERGEqdkrlqaLEEELEKVEAKLNAAVREKTSLSASVASLEKQLLELTRVNELLKAKfsedgtQKKMsSL 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1755 KLEKM-------AHEKEKIAKKINKveEVKAVLAQK--TETMME----KEKNLASEEKKVREEAKNQELdgqelaLKE-D 1820
Cdd:pfam15905 158 SMELMklrnkleAKMKEVMAKQEGM--EGKLQVTQKnlEHSKGKvaqlEEKLVSTEKEKIEEKSETEKL------LEYiT 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1821 ELYEEAEKLEDKREALAKEEEMLA------------LYEKNLSLEEEMLAQEAKHQM-EEEKRLALEKDRRPEE--VKHL 1885
Cdd:pfam15905 230 ELSCVSEQVEKYKLDIAQLEELLKekndeieslkqsLEEKEQELSKQIKDLNEKCKLlESEKEELLREYEEKEQtlNAEL 309
|
250 260
....*....|....*....|....
gi 2482565915 1886 QERREKLREQKqrlaQEKERIAQR 1909
Cdd:pfam15905 310 EELKEKLTLEE----QEHQKLQQK 329
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1753-1950 |
8.01e-03 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 40.51 E-value: 8.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1753 ARKLEKMAHEKEKIAKKINKVEEVKAVlaqktETMMEKEKNLASEEKKVREEAKNQELDGQELAlkeDELYEEAEKLEDK 1832
Cdd:cd00176 9 ADELEAWLSEKEELLSSTDYGDDLESV-----EALLKKHEALEAELAAHEERVEALNELGEQLI---EEGHPDAEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2482565915 1833 REALAKEEEML--ALYEKNLSLEEEMLAQEAKHQMEE------EKRLALEKDRRPEEVKHLQERREKLREQKQRLAQEKE 1904
Cdd:cd00176 81 LEELNQRWEELreLAEERRQRLEEALDLQQFFRDADDleqwleEKEAALASEDLGKDLESVEELLKKHKELEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2482565915 1905 RIAQ-----RKTELKVKKTRLAQMEESLSQERHKLSLEKERLTERGKALHD 1950
Cdd:cd00176 161 RLKSlnelaEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| |
