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Conserved domains on  [gi|2749806625|ref|XP_065999566.1|]
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uncharacterized protein OCT59_008722 [Rhizophagus irregularis]

Protein Classification

crinkler effector domain-containing protein( domain architecture ID 18344834)

crinkler effector domain-containing protein is a secreted effector that elicits necrosis in host cells

PubMed:  31699522|20847293

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Crinkler pfam20147
Crinkler effector protein N-terminal domain; Phytophthora sojae encodes hundreds of putative ...
 11-107 3.77e-12

Crinkler effector protein N-terminal domain; Phytophthora sojae encodes hundreds of putative host cytoplasmic effectors with conserved FLAK motifs following signal peptides, termed crinkling- and necrosis-inducing proteins (CRN) or Crinkler. Their functions and mechanisms in pathogenesis are mostly unknown. This N-terminal domain contains a ubiquitin-like fold.


:

Pssm-ID: 466308 [Multi-domain]  Cd Length: 103  Bit Score: 63.11  E-value: 3.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749806625  11 INLWC-IVRENRSIFKITIGLGNDLDDLKKVIKEGKPNYFVNADADeLILWRtnvASNILR---NKETAIESYLNEKLED 86
Cdd:pfam20147   1 LTLFClVVGEGGSAFSVKIDESETVGDLKKAIKEKKPNDFKDVAAD-LKLWK---VGSWLDdddLEELKELDLDGEEELD 76

                          90       100
                  ....*....|....*....|....*.
gi 2749806625  87 PADTVRNTFQNV-----VGNNIRVIV 107
Cdd:pfam20147  77 PLLKLTEYLSDVfpegpPEDHIHVLV 102
COG1373 super family cl26115
Predicted ATPase, AAA+ superfamily [General function prediction only];
141-247 1.89e-03

Predicted ATPase, AAA+ superfamily [General function prediction only];


The actual alignment was detected with superfamily member COG1373:

Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 41.08  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749806625 141 MISRNFFQEVESILLNGQSFVIHGPYQSGKSTFLFHlrtsFIGKSLDFAHLTmagvkgsiltnvrtgFYDYMSFMLFKET 220
Cdd:COG1373     4 MIKRKILDKLLKLLDNRKAVVITGPRQVGKTTLLKQ----LAKELENILYIN---------------LDDPRLRALAEED 64

                          90       100
                  ....*....|....*....|....*..
gi 2749806625 221 LDETKTfAHIYNLKDPLYILIDEFQYI 247
Cdd:COG1373    65 PDDLLE-ALKELYPGKTYLFLDEIQRV 90
 
Name Accession Description Interval E-value
Crinkler pfam20147
Crinkler effector protein N-terminal domain; Phytophthora sojae encodes hundreds of putative ...
 11-107 3.77e-12

Crinkler effector protein N-terminal domain; Phytophthora sojae encodes hundreds of putative host cytoplasmic effectors with conserved FLAK motifs following signal peptides, termed crinkling- and necrosis-inducing proteins (CRN) or Crinkler. Their functions and mechanisms in pathogenesis are mostly unknown. This N-terminal domain contains a ubiquitin-like fold.


Pssm-ID: 466308 [Multi-domain]  Cd Length: 103  Bit Score: 63.11  E-value: 3.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749806625  11 INLWC-IVRENRSIFKITIGLGNDLDDLKKVIKEGKPNYFVNADADeLILWRtnvASNILR---NKETAIESYLNEKLED 86
Cdd:pfam20147   1 LTLFClVVGEGGSAFSVKIDESETVGDLKKAIKEKKPNDFKDVAAD-LKLWK---VGSWLDdddLEELKELDLDGEEELD 76

                          90       100
                  ....*....|....*....|....*.
gi 2749806625  87 PADTVRNTFQNV-----VGNNIRVIV 107
Cdd:pfam20147  77 PLLKLTEYLSDVfpegpPEDHIHVLV 102
COG1373 COG1373
Predicted ATPase, AAA+ superfamily [General function prediction only];
141-247 1.89e-03

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 41.08  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749806625 141 MISRNFFQEVESILLNGQSFVIHGPYQSGKSTFLFHlrtsFIGKSLDFAHLTmagvkgsiltnvrtgFYDYMSFMLFKET 220
Cdd:COG1373     4 MIKRKILDKLLKLLDNRKAVVITGPRQVGKTTLLKQ----LAKELENILYIN---------------LDDPRLRALAEED 64

                          90       100
                  ....*....|....*....|....*..
gi 2749806625 221 LDETKTfAHIYNLKDPLYILIDEFQYI 247
Cdd:COG1373    65 PDDLLE-ALKELYPGKTYLFLDEIQRV 90
 
Name Accession Description Interval E-value
Crinkler pfam20147
Crinkler effector protein N-terminal domain; Phytophthora sojae encodes hundreds of putative ...
 11-107 3.77e-12

Crinkler effector protein N-terminal domain; Phytophthora sojae encodes hundreds of putative host cytoplasmic effectors with conserved FLAK motifs following signal peptides, termed crinkling- and necrosis-inducing proteins (CRN) or Crinkler. Their functions and mechanisms in pathogenesis are mostly unknown. This N-terminal domain contains a ubiquitin-like fold.


Pssm-ID: 466308 [Multi-domain]  Cd Length: 103  Bit Score: 63.11  E-value: 3.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749806625  11 INLWC-IVRENRSIFKITIGLGNDLDDLKKVIKEGKPNYFVNADADeLILWRtnvASNILR---NKETAIESYLNEKLED 86
Cdd:pfam20147   1 LTLFClVVGEGGSAFSVKIDESETVGDLKKAIKEKKPNDFKDVAAD-LKLWK---VGSWLDdddLEELKELDLDGEEELD 76

                          90       100
                  ....*....|....*....|....*.
gi 2749806625  87 PADTVRNTFQNV-----VGNNIRVIV 107
Cdd:pfam20147  77 PLLKLTEYLSDVfpegpPEDHIHVLV 102
COG1373 COG1373
Predicted ATPase, AAA+ superfamily [General function prediction only];
141-247 1.89e-03

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 41.08  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2749806625 141 MISRNFFQEVESILLNGQSFVIHGPYQSGKSTFLFHlrtsFIGKSLDFAHLTmagvkgsiltnvrtgFYDYMSFMLFKET 220
Cdd:COG1373     4 MIKRKILDKLLKLLDNRKAVVITGPRQVGKTTLLKQ----LAKELENILYIN---------------LDDPRLRALAEED 64

                          90       100
                  ....*....|....*....|....*..
gi 2749806625 221 LDETKTfAHIYNLKDPLYILIDEFQYI 247
Cdd:COG1373    65 PDDLLE-ALKELYPGKTYLFLDEIQRV 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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