|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00309 |
PTZ00309 |
glucose-6-phosphate 1-dehydrogenase; Provisional |
386-875 |
7.75e-113 |
|
glucose-6-phosphate 1-dehydrogenase; Provisional
Pssm-ID: 240353 [Multi-domain] Cd Length: 542 Bit Score: 355.98 E-value: 7.75e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 386 PMDQNDFLTFILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEffsQISNDIFSSINTNIfiRNPAIR 465
Cdd:PTZ00309 48 DEDKSRALTIIVLGASGDLAKKKTFPALFQLYCEGLLPSEVNIVGYARSKMSDVE---RWKKETLARFFKRL--DDRECH 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 466 FDfpsvitEFKSRCSRICLKYDDSSFFDRFTEKVREIDRNSV----TSHRMVYLATPSEAYQNILRVVTSCCKPENGWFR 541
Cdd:PTZ00309 123 LE------QFLKHISYISGSYDEDEDFKRLNKLIERMEEAFQgpekGGNRLFYLALPPSVFASVCEGIHRGCMSKNGWVR 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 542 VMLEKPFGRDLKSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILSSKISTK-YSRIFNRKYIRSVHILLKEEIGSFGR 620
Cdd:PTZ00309 197 VIVEKPFGRDLESSEELSNQLEPLFDESQLYRIDHYLGKEMVQNLIVLRFANRvFEPLWNRNNIACVQITFKEDIGTEGR 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 621 -DYFESYGIIRDMIQNHGMQLLSLIAMhcEHKKHLP-----QNKFSVLKCVRTVQLSDLVIGQYSESEKGC--SYRAEKG 692
Cdd:PTZ00309 277 gGYFDSYGIIRDVMQNHLLQILALLAM--EKPVSLSaedirDEKVKVLKCIEPIKMEECVLGQYTASADGSipGYLEDEG 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 693 VPKDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKcDPPKDI--CYDFVPTHLVYRIQPQPSVFWRkd 770
Cdd:PTZ00309 355 VPKDSTTPTFAAAVLHINNDRWEGVPFILEAGKALEERYVEIRIQFK-GVDEFRpsGDDTQRNELVIRAQPSEAMYLK-- 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 771 FTEVKVGEVKDSYASDLEnekyfnteekilVDVEASAAKRtIEGAYELLFFYAFSNKRDIFPTIKQVNEAWRIFTPVLEE 850
Cdd:PTZ00309 432 ITAKVPGLSNDLHQTELD------------LTYKTRYNVR-LPDAYERLILDALLGDSTNFVRKDELDVAWRIFTPLLHQ 498
|
490 500
....*....|....*....|....*
gi 85001069 851 ISEKKVEPFLYPRGSPGPKEADALL 875
Cdd:PTZ00309 499 IDRGEVKPEPYPFGSRGPKEADELI 523
|
|
| zwf |
TIGR00871 |
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ... |
395-875 |
3.86e-104 |
|
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273312 [Multi-domain] Cd Length: 487 Bit Score: 331.21 E-value: 3.86e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 395 FILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEFFSQISNDIfssintnifIRNPAIRFDFPsvITE 474
Cdd:TIGR00871 5 LVIFGASGDLARKKLFPALYRLFRNGLLPPDFRIVGVARRDWSVEEFRKVVREAI---------IKFETDEIDEQ--WDE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 475 FKSRCSRICLKYDDSSFFDRFTEKVREIDRNSVT-SHRMVYLATPSEAYQNILRVVTSCCKPENG-WFRVMLEKPFGRDL 552
Cdd:TIGR00871 74 FAQRLSYVSGDVDDDESYDSLAELLEQLDKTYGTeGNRLFYLATPPSLFGTIIKQLKKHGLNEQGkWSRVVVEKPFGHDL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 553 KSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILSSKISTK-YSRIFNRKYIRSVHILLKEEIGSFGR-DYFESYGIIR 630
Cdd:TIGR00871 154 ASAQELNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQiFEPLWNRRYIDHVQITVAESFGVEGRgGYYDKSGALR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 631 DMIQNHGMQLLSLIAMHcehkkhlPQNKFS----------VLKCVRTVQLSD--LVIGQYSESEKGC----SYRAEKGVP 694
Cdd:TIGR00871 234 DMVQNHLLQLLALVAME-------PPVSFDadsirdekvkVLKALRPIDPDDnnTVRGQYGAGEIGGvsvpGYLEEEGVD 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 695 KDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKcDPP----KDICYDFVPTH-LVYRIQPQPSVfwrk 769
Cdd:TIGR00871 307 KDSNTETFAALKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFR-DVPsllfKANERDANPRNaLVIRIQPDEGV---- 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 770 dftEVKVGEVKDSYAsdlenekyFNTEEkilVDVE---ASAAKRTIEGAYELLFFYAFSNKRDIFPTIKQVNEAWRIFTP 846
Cdd:TIGR00871 382 ---YLKFNAKKPGLN--------FETRP---VKLDfsyASRFGELLPEAYERLLLDALLGDHTLFARDDEVEEAWRIVTP 447
|
490 500 510
....*....|....*....|....*....|
gi 85001069 847 VLEEISEKKVEPFL-YPRGSPGPKEADALL 875
Cdd:TIGR00871 448 ILEAWAANKGPSPPnYPAGSWGPKEADELI 477
|
|
| Zwf |
COG0364 |
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ... |
394-875 |
7.45e-90 |
|
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440133 [Multi-domain] Cd Length: 495 Bit Score: 293.52 E-value: 7.45e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 394 TFILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEFFSQISNDIfssintNIFIRNPairFDfPSVIT 473
Cdd:COG0364 11 DLVIFGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSDEEFREEVREAL------EEFSRKP---FD-EEVWE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 474 EFKSRCSRICLKYDDSSFFDRFTEKVREIDRNSVTSHRMVYLATPSEAYQNIlrvvtscCK--------PENGWFRVMLE 545
Cdd:COG0364 81 RFLERLHYVSGDFTDPEGYERLKELLEELDEERTPGNRVFYLATPPSLFGPI-------CEnlgaaglaTEGGWRRVVIE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 546 KPFGRDLKSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILSskistkySR----IF----NRKYIRSVHILLKEEIGS 617
Cdd:COG0364 154 KPFGHDLASARELNDELGRVFDESQIYRIDHYLGKETVQNLLA-------LRfanaLFeplwNRNYIDHVQITVAETVGV 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 618 FGR-DYFESYGIIRDMIQNHGMQLLSLIAMHcehkkhlPQNKFS----------VLKCVRTVQLSDL----VIGQYSESE 682
Cdd:COG0364 227 EGRgGYYDGAGALRDMVQNHLLQLLCLVAME-------PPASLDadairdekvkVLRALRPITPEDVaentVRGQYTAGW 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 683 KG----CSYRAEKGVPKDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKcDPPKDIcydFVPTH---- 754
Cdd:COG0364 300 IGgepvPGYREEPGVAPDSTTETFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFK-PVPHSL---FRETAeelp 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 755 ---LVYRIQPQPSVFWR---KDF-TEVKVGEVKdsyaSDLENEKYFNTeekilvdveasaakRTIEgAYELLFFYAFSNK 827
Cdd:COG0364 376 pnrLVIRIQPDEGISLRfnaKVPgLGMRLRPVS----LDFSYSDAFGE--------------RSPE-AYERLLLDVMRGD 436
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 85001069 828 RDIFPTIKQVNEAWRIFTPVLEEISEKKVEPFLYPRGSPGPKEADALL 875
Cdd:COG0364 437 QTLFMRRDEVEAAWRWVDPILEAWAEEPEPPPPYPAGSWGPEAADALL 484
|
|
| G6PD_C |
pfam02781 |
Glucose-6-phosphate dehydrogenase, C-terminal domain; |
598-875 |
4.43e-68 |
|
Glucose-6-phosphate dehydrogenase, C-terminal domain;
Pssm-ID: 460694 Cd Length: 295 Bit Score: 228.09 E-value: 4.43e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 598 IFNRKYIRSVHILLKEEIGSFGR-DYFESYGIIRDMIQNHGMQLLSLIAMhcEhkkhlPQNKFS----------VLKCVR 666
Cdd:pfam02781 13 LWNRNYIDHVQITVAETLGVEGRgGYYDQAGALRDMVQNHLLQLLALVAM--E-----PPVSFDaedirdekvkVLRSLR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 667 TVQLSDL----VIGQYSESEKG----CSYRAEKGVPKDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAF 738
Cdd:pfam02781 86 PITPEDVednvVRGQYGAGWIGgepvPGYREEEGVPPDSRTETFAALKLFIDNWRWAGVPFYLRTGKRLPERVTEIRIQF 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 739 KcDPPKDI---CYDFVPTHLVYRIQPQPSVFWRKdftEVKV-GEVKDSYASDLEnekyFNTEEkilvdveasAAKRTIEG 814
Cdd:pfam02781 166 K-DVPHNLfrdPGTLPPNELVIRIQPDEGIYLKF---NAKVpGLGMRLRPVELD----FSYSD---------RFGERIPE 228
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 85001069 815 AYELLFFYAFSNKRDIFPTIKQVNEAWRIFTPVLEEISEKKVEPflYPRGSPGPKEADALL 875
Cdd:pfam02781 229 AYERLLLDVMRGDQTLFVRSDEVEAAWRIVDPILEAWDEEKPPP--YPAGSWGPKAADELL 287
|
|
| 6PGL |
cd01400 |
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ... |
107-370 |
1.03e-52 |
|
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.
Pssm-ID: 238694 [Multi-domain] Cd Length: 219 Bit Score: 183.15 E-value: 1.03e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 107 EGFVLTASHLILHKIRRKLSKspDVTVKIGLSGGSTPRGIYRFLGNMKDldIDFNRIIFFLVDERYVPSDDEMSNIRLLR 186
Cdd:cd01400 1 EALAEALADRIAEALAAAIAK--RGRFSLALSGGSTPKPLYELLAAAPA--LDWSKVHVFLGDERCVPPDDPDSNYRLAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 187 NTLLKHWPVPESNLVFPDTSLPLEECVKKYEADLEAVFGVVTthvnsntdpahrvagksemsstefesfdhsfykpkysi 266
Cdd:cd01400 77 EALLSHVAIPAANIHPIPTELGPEDAAAAYEKELRALFGGVP-------------------------------------- 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 267 VPDLVTLGIGEDFHIAGLFPEylstlDSSYVTDTLHRVMATYTETTVVRERISCSLPFLSCAPTKLFFLKGERKKRIWNT 346
Cdd:cd01400 119 PFDLVLLGMGPDGHTASLFPG-----HPALLEETDRLVVAVTDSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEALKR 193
|
250 260
....*....|....*....|....
gi 85001069 347 MLQYRhyDPIRFPATQIFTKPGCI 370
Cdd:cd01400 194 ALAGP--DPEELPAARVLPRPGEV 215
|
|
| Glucosamine_iso |
pfam01182 |
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; |
105-373 |
7.38e-38 |
|
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
Pssm-ID: 460101 [Multi-domain] Cd Length: 222 Bit Score: 141.22 E-value: 7.38e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 105 TEEGFVLTASHLILHKIRRKLSKSPDVTvkIGLSGGSTPRGIYRFLGNMKDlDIDFNRIIFFLVDERYVPSDDEMSNIRL 184
Cdd:pfam01182 2 DAEALAQALAERLAEALEAALAERGRFT--LALSGGSTPKPLYELLAAAPA-RLDWSRVHVFWGDERCVPPDDPDSNYGM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 185 LRNTLLKHWPVPESNLV-FPDTSLPLEECVKKYEADLEAVFGvvtthvnSNTDPahrvagksemsstefesfdhsfykpk 263
Cdd:pfam01182 79 AREALLSHVPIPASNVHpIPASAADPEEAAAAYEAELRELLP-------DLELP-------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 264 ysiVPDLVTLGIGEDFHIAGLFPeylstlDSSYVTDTLHRVMATYTETTVVRERISCSLPFLSCAPTKLFFLKGERKKRI 343
Cdd:pfam01182 126 ---VFDLVLLGMGPDGHTASLFP------GSPALEETDRLVVAVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADA 196
|
250 260 270
....*....|....*....|....*....|
gi 85001069 344 WNTMLQyrhYDPIRFPATQIFtkPGCIAVL 373
Cdd:pfam01182 197 LRRALA---GDPDPLPAALVR--PGAGETV 221
|
|
| NagB |
COG0363 |
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ... |
103-374 |
1.95e-32 |
|
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440132 [Multi-domain] Cd Length: 248 Bit Score: 126.43 E-value: 1.95e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 103 CHTEEGFVLTASHLILHKIRRKLSKSPDVTvkIGLSGGSTPRGIYRFLGNM-KDLDIDFNRIIFFLVDERY-VPSDDEMS 180
Cdd:COG0363 7 FPDAEELAAAAAERAAERIAEAIAEKGRAV--LGLAGGSTPLGLYEELARLhKEGGLDWSRVHVFNLDEYVgLPPDHPQS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 181 NIRLLRNTLLKHWPVPESNLVFPDTSL--PLEECvKKYEADLEAVFGVvtthvnsntdpahrvagksemsstefesfdhs 258
Cdd:COG0363 85 NRRFMREALLDHVDIPPENIHIPDGEAedPEAAA-ARYEALIAEAGGI-------------------------------- 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 259 fykpkysivpDLVTLGIGEDFHIAGLFPeylstlDSSYVTDTLHRVMATY-----------TETTVVRERISCSLPFLSC 327
Cdd:COG0363 132 ----------DLQLLGIGEDGHIAFNFP------GSPFLSETDRVVTLDEstrqanarffgSIPKVPPQAITLGIPTIMK 195
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 85001069 328 APTKLFFLKGERKKRIWNTMLQyrhyDPI--RFPATQIFTKPGCIAVLD 374
Cdd:COG0363 196 AREILLLATGENKAEAVAAALE----GPVteEVPASILQGHPNVTWFLD 240
|
|
| pgl |
TIGR01198 |
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ... |
116-381 |
1.10e-26 |
|
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273494 [Multi-domain] Cd Length: 233 Bit Score: 109.39 E-value: 1.10e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 116 LILHKIRRKLSKSPDVTvkIGLSGGSTPRGIYRFLGnmkDLDIDFNRIIFFLVDERYVPSDDEMSNIRLLRNTLLKHWPV 195
Cdd:TIGR01198 15 RIATKLQTALAERGQFS--LALSGGRSPIALLEALA---AQPLDWSRIHLFLGDERYVPLDHADSNTGLAREALLDRVAI 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 196 PESNLVFPDTSLPL-EECVKKYEADLeavfgvvtthvnsntdpahrvagksemsstefesfdHSFYKPKYSIVPDLVTLG 274
Cdd:TIGR01198 90 PASNIHPMPTELSDiEEAAELYEQEL------------------------------------AAAFQPIVFPVFDLLLLG 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 275 IGEDFHIAGLFPEylstldSSYVTDTLHRVMATYTETTVVRERISCSLPFLSCAPTKLFFLKGERKKRIWNTMLQYRHyD 354
Cdd:TIGR01198 134 MGPDGHTASLFPH------TPALQETERLVTVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAVEA-E 206
|
250 260
....*....|....*....|....*..
gi 85001069 355 PIRFPATQIFTKPGCIAVLDSSTIRKV 381
Cdd:TIGR01198 207 PYPLPAAGVLHSGKTLWLLDYAAARKL 233
|
|
| nagB |
PRK00443 |
glucosamine-6-phosphate deaminase; Provisional |
113-315 |
7.57e-12 |
|
glucosamine-6-phosphate deaminase; Provisional
Pssm-ID: 179028 [Multi-domain] Cd Length: 261 Bit Score: 66.39 E-value: 7.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 113 ASHLILHKIRRKLSKSPDVTVkIGLSGGSTPRGIYRFLGNM-KDLDIDFNRIIFFLVDErYV--PSDDEMSNIRLLRNTL 189
Cdd:PRK00443 16 AARHIANRINAFLPTKERPFV-LGLATGSSPLETYKALIELhKAGKVDFSRVTTFNLDE-YVglPADHPESYRYFMRENF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 190 LKHWPVPESNLVFPD--TSLPLEECvKKYEADLEAVFGVvtthvnsntdpahrvagksemsstefesfdhsfykpkysiv 267
Cdd:PRK00443 94 FDHVDIPPENINLLNgnAPDPEAEC-RRYEEKIKSAGGI----------------------------------------- 131
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 85001069 268 pDLVTLGIGEDFHIAglFPEYLSTLDSSYVTDTLhrvmatyTETTVVR 315
Cdd:PRK00443 132 -DLQILGIGENGHIA--FNEPGSSFASRTRIKTL-------TEDTRIA 169
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00309 |
PTZ00309 |
glucose-6-phosphate 1-dehydrogenase; Provisional |
386-875 |
7.75e-113 |
|
glucose-6-phosphate 1-dehydrogenase; Provisional
Pssm-ID: 240353 [Multi-domain] Cd Length: 542 Bit Score: 355.98 E-value: 7.75e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 386 PMDQNDFLTFILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEffsQISNDIFSSINTNIfiRNPAIR 465
Cdd:PTZ00309 48 DEDKSRALTIIVLGASGDLAKKKTFPALFQLYCEGLLPSEVNIVGYARSKMSDVE---RWKKETLARFFKRL--DDRECH 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 466 FDfpsvitEFKSRCSRICLKYDDSSFFDRFTEKVREIDRNSV----TSHRMVYLATPSEAYQNILRVVTSCCKPENGWFR 541
Cdd:PTZ00309 123 LE------QFLKHISYISGSYDEDEDFKRLNKLIERMEEAFQgpekGGNRLFYLALPPSVFASVCEGIHRGCMSKNGWVR 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 542 VMLEKPFGRDLKSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILSSKISTK-YSRIFNRKYIRSVHILLKEEIGSFGR 620
Cdd:PTZ00309 197 VIVEKPFGRDLESSEELSNQLEPLFDESQLYRIDHYLGKEMVQNLIVLRFANRvFEPLWNRNNIACVQITFKEDIGTEGR 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 621 -DYFESYGIIRDMIQNHGMQLLSLIAMhcEHKKHLP-----QNKFSVLKCVRTVQLSDLVIGQYSESEKGC--SYRAEKG 692
Cdd:PTZ00309 277 gGYFDSYGIIRDVMQNHLLQILALLAM--EKPVSLSaedirDEKVKVLKCIEPIKMEECVLGQYTASADGSipGYLEDEG 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 693 VPKDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKcDPPKDI--CYDFVPTHLVYRIQPQPSVFWRkd 770
Cdd:PTZ00309 355 VPKDSTTPTFAAAVLHINNDRWEGVPFILEAGKALEERYVEIRIQFK-GVDEFRpsGDDTQRNELVIRAQPSEAMYLK-- 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 771 FTEVKVGEVKDSYASDLEnekyfnteekilVDVEASAAKRtIEGAYELLFFYAFSNKRDIFPTIKQVNEAWRIFTPVLEE 850
Cdd:PTZ00309 432 ITAKVPGLSNDLHQTELD------------LTYKTRYNVR-LPDAYERLILDALLGDSTNFVRKDELDVAWRIFTPLLHQ 498
|
490 500
....*....|....*....|....*
gi 85001069 851 ISEKKVEPFLYPRGSPGPKEADALL 875
Cdd:PTZ00309 499 IDRGEVKPEPYPFGSRGPKEADELI 523
|
|
| zwf |
TIGR00871 |
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ... |
395-875 |
3.86e-104 |
|
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273312 [Multi-domain] Cd Length: 487 Bit Score: 331.21 E-value: 3.86e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 395 FILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEFFSQISNDIfssintnifIRNPAIRFDFPsvITE 474
Cdd:TIGR00871 5 LVIFGASGDLARKKLFPALYRLFRNGLLPPDFRIVGVARRDWSVEEFRKVVREAI---------IKFETDEIDEQ--WDE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 475 FKSRCSRICLKYDDSSFFDRFTEKVREIDRNSVT-SHRMVYLATPSEAYQNILRVVTSCCKPENG-WFRVMLEKPFGRDL 552
Cdd:TIGR00871 74 FAQRLSYVSGDVDDDESYDSLAELLEQLDKTYGTeGNRLFYLATPPSLFGTIIKQLKKHGLNEQGkWSRVVVEKPFGHDL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 553 KSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILSSKISTK-YSRIFNRKYIRSVHILLKEEIGSFGR-DYFESYGIIR 630
Cdd:TIGR00871 154 ASAQELNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQiFEPLWNRRYIDHVQITVAESFGVEGRgGYYDKSGALR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 631 DMIQNHGMQLLSLIAMHcehkkhlPQNKFS----------VLKCVRTVQLSD--LVIGQYSESEKGC----SYRAEKGVP 694
Cdd:TIGR00871 234 DMVQNHLLQLLALVAME-------PPVSFDadsirdekvkVLKALRPIDPDDnnTVRGQYGAGEIGGvsvpGYLEEEGVD 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 695 KDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKcDPP----KDICYDFVPTH-LVYRIQPQPSVfwrk 769
Cdd:TIGR00871 307 KDSNTETFAALKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFR-DVPsllfKANERDANPRNaLVIRIQPDEGV---- 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 770 dftEVKVGEVKDSYAsdlenekyFNTEEkilVDVE---ASAAKRTIEGAYELLFFYAFSNKRDIFPTIKQVNEAWRIFTP 846
Cdd:TIGR00871 382 ---YLKFNAKKPGLN--------FETRP---VKLDfsyASRFGELLPEAYERLLLDALLGDHTLFARDDEVEEAWRIVTP 447
|
490 500 510
....*....|....*....|....*....|
gi 85001069 847 VLEEISEKKVEPFL-YPRGSPGPKEADALL 875
Cdd:TIGR00871 448 ILEAWAANKGPSPPnYPAGSWGPKEADELI 477
|
|
| PRK05722 |
PRK05722 |
glucose-6-phosphate 1-dehydrogenase; Validated |
381-876 |
6.21e-96 |
|
glucose-6-phosphate 1-dehydrogenase; Validated
Pssm-ID: 235579 [Multi-domain] Cd Length: 495 Bit Score: 309.75 E-value: 6.21e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 381 VRLKIPMDQNDFltfILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEFFSQISndifSSINTniFIR 460
Cdd:PRK05722 1 MRLPRTAEPCDL---VIFGATGDLARRKLLPALYNLYKAGLLPEDFRIIGVARRDWSDEDFREVVR----EALKE--FAR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 461 NPairFDfPSVITEFKSRCSRICLKYDDSSFFDRFTEKVREIDRNSVT-SHRMVYLATPSEAYQNILRVVTSC-CKPENG 538
Cdd:PRK05722 72 TP---FD-EEVWERFLSRLYYVSGDVTDPESYERLKELLEELDEERGTgGNRVFYLATPPSLFGTICENLAAAgLNEGGG 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 539 WFRVMLEKPFGRDLKSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCIL----SSKIstkYSRIFNRKYIRSVHILLKEE 614
Cdd:PRK05722 148 WRRVVIEKPFGHDLASARELNDQVGEVFKEEQIYRIDHYLGKETVQNLLalrfANAL---FEPLWNRNYIDHVQITVAET 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 615 IGSFGR-DYFESYGIIRDMIQNHGMQLLSLIAMHcehkkhlPQNKFS----------VLKCVRTVQLSDL----VIGQYS 679
Cdd:PRK05722 225 VGVEGRgGYYDKSGALRDMVQNHLLQLLALVAME-------PPASLDadsirdekvkVLRALRPITPEDVkentVRGQYT 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 680 E----SEKGCSYRAEKGVPKDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKCdPPKDIcydFVPTH- 754
Cdd:PRK05722 298 AgwigGKPVPGYREEEGVNPDSTTETFVALKLEIDNWRWAGVPFYLRTGKRLPKKVTEIVIVFKP-PPHNL---FEESAe 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 755 ------LVYRIQPQPSVFWRkdftevkvgevkdsyasdlenekyFNT----EEKILVDVE-----ASAAKRTIEGAYELL 819
Cdd:PRK05722 374 elgpnkLVIRIQPDEGISLR------------------------FNAkvpgEGMELRPVKldfsySEAFGEASPEAYERL 429
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 85001069 820 FFYAFSNKRDIFPTIKQVNEAWRIFTPVLEEISEKKVEPFLYPRGSPGPKEADALLS 876
Cdd:PRK05722 430 LLDVMLGDQTLFVRRDEVEAAWKWVDPILEAWEADGGPPPPYPAGTWGPEAADALLA 486
|
|
| PLN02539 |
PLN02539 |
glucose-6-phosphate 1-dehydrogenase |
393-876 |
3.63e-93 |
|
glucose-6-phosphate 1-dehydrogenase
Pssm-ID: 178154 [Multi-domain] Cd Length: 491 Bit Score: 302.41 E-value: 3.63e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 393 LTFILFGSGGDLARRKIYPALFHLFYLGFL-PHKFHILAISRSHIDFEEFFSQISNdifssintniFIRNPAIrfDFPSV 471
Cdd:PLN02539 18 LSIIVLGASGDLAKKKTFPALFNLYRQGFLpPDEVHIFGYARSKITDEELRDRIRG----------YLKDEKN--APAEA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 472 ITEFKSRCSRICLKYDDSSFFDRFTEKVR--EIDRNS--VTSHRMVYLATPSEAYQNILRVVTSCC-KPENGWFRVMLEK 546
Cdd:PLN02539 86 VSKFLQLIKYVSGAYDSEEGFRRLDKEISehEISKNSaeGSSRRLFYLALPPSVYPPVCKMIKKCCmNKSGLWTRIVVEK 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 547 PFGRDLKSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILSSKISTK-YSRIFNRKYIRSVHILLKEEIGSFGRD-YFE 624
Cdd:PLN02539 166 PFGKDLESAEELSSQIGELFDESQLYRIDHYLGKELVQNLLVLRFANRfFLPLWNRDNIANVQIVFREDFGTEGRGgYFD 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 625 SYGIIRDMIQNHGMQLLSLIAMH--CEHK-KHLPQNKFSVLKCVRTVQLSDLVIGQYSesekgcSYRAEKGVPKDSLCAT 701
Cdd:PLN02539 246 EYGIIRDIIQNHLLQVLCLVAMEkpVSLKpEHIRDEKVKVLQSVEPIKDEEVVLGQYE------GYRDDPTVPDDSNTPT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 702 YCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKcDPPKDI--CYDFVPTHLVYRIQPQPSVFWRkdFTEVKVGEV 779
Cdd:PLN02539 320 FASVVLRINNERWEGVPFILKAGKALDSRKAEIRVQFK-DVPGDIfkCQKQGRNEFVIRLQPSEAMYMK--LTVKQPGLE 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 780 KDSYASDLE---NEKYFNTeekilvdveasaakrTIEGAYELLFFYAFSNKRDIFPTIKQVNEAWRIFTPVLEEISEKKV 856
Cdd:PLN02539 397 MSTVQSELDlsyGQRYQDV---------------VIPEAYERLILDTIRGDQQHFVRRDELKAAWEIFTPLLHRIDAGKV 461
|
490 500
....*....|....*....|
gi 85001069 857 EPFLYPRGSPGPKEADALLS 876
Cdd:PLN02539 462 KPIPYKQGSRGPAEADELLE 481
|
|
| Zwf |
COG0364 |
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ... |
394-875 |
7.45e-90 |
|
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440133 [Multi-domain] Cd Length: 495 Bit Score: 293.52 E-value: 7.45e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 394 TFILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEFFSQISNDIfssintNIFIRNPairFDfPSVIT 473
Cdd:COG0364 11 DLVIFGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSDEEFREEVREAL------EEFSRKP---FD-EEVWE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 474 EFKSRCSRICLKYDDSSFFDRFTEKVREIDRNSVTSHRMVYLATPSEAYQNIlrvvtscCK--------PENGWFRVMLE 545
Cdd:COG0364 81 RFLERLHYVSGDFTDPEGYERLKELLEELDEERTPGNRVFYLATPPSLFGPI-------CEnlgaaglaTEGGWRRVVIE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 546 KPFGRDLKSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILSskistkySR----IF----NRKYIRSVHILLKEEIGS 617
Cdd:COG0364 154 KPFGHDLASARELNDELGRVFDESQIYRIDHYLGKETVQNLLA-------LRfanaLFeplwNRNYIDHVQITVAETVGV 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 618 FGR-DYFESYGIIRDMIQNHGMQLLSLIAMHcehkkhlPQNKFS----------VLKCVRTVQLSDL----VIGQYSESE 682
Cdd:COG0364 227 EGRgGYYDGAGALRDMVQNHLLQLLCLVAME-------PPASLDadairdekvkVLRALRPITPEDVaentVRGQYTAGW 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 683 KG----CSYRAEKGVPKDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKcDPPKDIcydFVPTH---- 754
Cdd:COG0364 300 IGgepvPGYREEPGVAPDSTTETFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFK-PVPHSL---FRETAeelp 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 755 ---LVYRIQPQPSVFWR---KDF-TEVKVGEVKdsyaSDLENEKYFNTeekilvdveasaakRTIEgAYELLFFYAFSNK 827
Cdd:COG0364 376 pnrLVIRIQPDEGISLRfnaKVPgLGMRLRPVS----LDFSYSDAFGE--------------RSPE-AYERLLLDVMRGD 436
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 85001069 828 RDIFPTIKQVNEAWRIFTPVLEEISEKKVEPFLYPRGSPGPKEADALL 875
Cdd:COG0364 437 QTLFMRRDEVEAAWRWVDPILEAWAEEPEPPPPYPAGSWGPEAADALL 484
|
|
| PLN02333 |
PLN02333 |
glucose-6-phosphate 1-dehydrogenase |
289-874 |
5.88e-89 |
|
glucose-6-phosphate 1-dehydrogenase
Pssm-ID: 215191 [Multi-domain] Cd Length: 604 Bit Score: 294.58 E-value: 5.88e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 289 LSTLDSSYVTDTLHRVMATYTETTVVRERISC----SLPFLSCAPTKLFFLK---GERKKRIWNTMLQY-----RHYDPI 356
Cdd:PLN02333 1 MATLSSSHSCPYARSYSYSLSPSSSSSHSSVVdphrSLSFLSAIPQGLNPAKlcvRSQRNSYQNVVLMQdgavaTPSNPV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 357 RFPATQIFTKPGCIAVLDSSTIRKVRLKIPM-DQNDFLTFILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSH 435
Cdd:PLN02333 81 ENDSSFKKLKDGLLSSIPSSEEDKVVAEFDGnKDESTVSITVVGASGDLAKKKIFPALFALYYEGCLPEHFTIFGYARSK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 436 IDFEEFFSQISNDIFSSINTnifirnpaiRFDFPSVITEFKSRCSRICLKYDDSSFFDRFTEKVREIDRNSVtSHRMVYL 515
Cdd:PLN02333 161 MTDAELRNMVSKTLTCRIDK---------RENCGEKMEEFLKRCFYHSGQYDSQEHFAELDKKLKEHEGGRV-SNRLFYL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 516 ATPSEAYQNILRVVTSCCKPENGWFRVMLEKPFGRDLKSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILSSKISTK- 594
Cdd:PLN02333 231 SIPPNIFVDAVKCASSSASSVNGWTRVIVEKPFGRDSESSAALTKSLKQYLEEDQIFRIDHYLGKELVENLSVLRFSNLi 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 595 YSRIFNRKYIRSVHILLKEEIGSFGR-DYFESYGIIRDMIQNHGMQLLSLIAMHCE---HKKHLPQNKFSVLKCVRTVQL 670
Cdd:PLN02333 311 FEPLWSRQYIRNVQFIFSEDFGTEGRgGYFDNYGIIRDIMQNHLLQILALFAMETPvslDAEDIRNEKVKVLRSMRPIQL 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 671 SDLVIGQYSESEKGC----SYRAEKGVPKDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKCDPPK-- 744
Cdd:PLN02333 391 EDVVIGQYKSHTKGGvtypAYTDDKTVPKGSLTPTFAAAALFIDNARWDGVPFLMKAGKALHTKSAEIRVQFRHVPGNly 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 745 ------DIcyDFVPTHLVYRIQPQPSVFWRKDFTEVKVGEVKDSyaSDLeNEKYfnteekilvdveASAAKRTIEGAYEL 818
Cdd:PLN02333 471 nrnfgtDL--DQATNELVIRVQPDEAIYLKINNKVPGLGMRLDR--SNL-NLLY------------AARYSKEIPDAYER 533
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 85001069 819 LFFYAFSNKRDIFPTIKQVNEAWRIFTPVLEEISEKKVEPFLYPRGSPGPKEADAL 874
Cdd:PLN02333 534 LLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPEYYPYGSRGPVGAHYL 589
|
|
| PLN02640 |
PLN02640 |
glucose-6-phosphate 1-dehydrogenase |
393-876 |
6.65e-88 |
|
glucose-6-phosphate 1-dehydrogenase
Pssm-ID: 215344 [Multi-domain] Cd Length: 573 Bit Score: 291.15 E-value: 6.65e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 393 LTFILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEFFSQISNDIFSSINTnifirnpaiRFDFPSVI 472
Cdd:PLN02640 89 LSITVVGASGDLAKKKIFPALFALFYEDWLPENFTVFGYARTKLTDEELRDMISSTLTCRIDQ---------RENCGDKM 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 473 TEFKSRCSRICLKYDDSSFFDRFTEKVREIDRNSVtSHRMVYLATPSEAYQNILRVVTSCCKPENGWFRVMLEKPFGRDL 552
Cdd:PLN02640 160 DQFLKRCFYHSGQYDSEEDFAELNKKLKEKEAGKL-SNRLFYLSIPPNIFVDVVRCASLRASSENGWTRVIVEKPFGRDS 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 553 KSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILSSKIST-KYSRIFNRKYIRSVHILLKEEIGSFGR-DYFESYGIIR 630
Cdd:PLN02640 239 ESSGELTRCLKQYLTEEQIFRIDHYLGKELVENLSVLRFSNlVFEPLWSRNYIRNVQLIFSEDFGTEGRgGYFDNYGIIR 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 631 DMIQNHGMQLLSLIAMHCE---HKKHLPQNKFSVLKCVRTVQLSDLVIGQYSESEKGC----SYRAEKGVPKDSLCATYC 703
Cdd:PLN02640 319 DIMQNHLLQILALFAMETPvslDAEDIRNEKVKVLRSMKPLQLEDVIVGQYKGHSKGGksypAYTDDPTVPKHSLTPTFA 398
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 704 TVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKCDP----PKDICYDF--VPTHLVYRIQPQPSVFWRKDFTEVKVG 777
Cdd:PLN02640 399 AAALFINNARWDGVPFLMKAGKALHTRRAEIRVQFRHVPgnlyKRNFGTDLdkATNELVLRVQPDEAIYLKINNKVPGLG 478
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 778 EVKDSyaSDLeNEKYfnteekilvdveASAAKRTIEGAYELLFFYAFSNKRDIFPTIKQVNEAWRIFTPVLEEISEKKVE 857
Cdd:PLN02640 479 MRLDR--SDL-NLLY------------RARYPREIPDAYERLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKII 543
|
490
....*....|....*....
gi 85001069 858 PFLYPRGSPGPKEADALLS 876
Cdd:PLN02640 544 PELYPYGSRGPVGAHYLAA 562
|
|
| PRK12853 |
PRK12853 |
glucose-6-phosphate dehydrogenase; |
386-875 |
2.69e-80 |
|
glucose-6-phosphate dehydrogenase;
Pssm-ID: 237233 [Multi-domain] Cd Length: 482 Bit Score: 267.54 E-value: 2.69e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 386 PMDQNDFLTFILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEFFSQISNDIFSSINTnifirnpaiR 465
Cdd:PRK12853 2 DTAPAPPCTLVIFGATGDLARRKLLPALYRLARAGLLPEDLRIIGVGRDDWSDEQWRARVRESLRAFGAD---------G 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 466 FDfPSVITEFKSRCSRICLKYDDSSFFDRFTEKVREidrnsvTSHRMVYLATPSEAYQNILRVVTSC-CKPEngWFRVML 544
Cdd:PRK12853 73 FD-DAVWDRLAARLSYVQGDVTDPADYARLAEALGP------GGNPVFYLAVPPSLFAPVVENLGAAgLLPE--GRRVVL 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 545 EKPFGRDLKSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILsskistkYSR--------IFNRKYIRSVHILLKEEIG 616
Cdd:PRK12853 144 EKPFGHDLASARALNATLAKVFDEDQIYRIDHFLGKETVQNLL-------ALRfanallepLWNRNHIDHVQITVAETLG 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 617 SFGR-DYFESYGIIRDMIQNHGMQLLSLIAMH---CEHKKHLPQNKFSVLKCVRTVQLSDL--VIGQYS----ESEKGCS 686
Cdd:PRK12853 217 VEGRgGFYDATGALRDMVQNHLLQLLALVAMEppaSFDADAVRDEKAKVLRAIRPLDPDDVhtVRGQYTagtvGGEPVPG 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 687 YRAEKGVPKDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKcDPPKDIcydFVPTH------LVYRIQ 760
Cdd:PRK12853 297 YREEPGVDPDSRTETFVALKLEIDNWRWAGVPFYLRTGKRLAERRTEIVITFK-PVPHAL---FRGTGveppnrLVIRLQ 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 761 PQPSVfwRKDFTeVKV-GEVKDsyasdlenekyfnteekiLVDVEASAAKRTIEG---AYELLFFYAFSNKRDIFPTIKQ 836
Cdd:PRK12853 373 PDEGI--SLELN-VKRpGPGMR------------------LRPVELDADYADDERpleAYERLLLDVLRGDPTLFVRADE 431
|
490 500 510
....*....|....*....|....*....|....*....
gi 85001069 837 VNEAWRIFTPVLEEISEKKVEPFLYPRGSPGPKEADALL 875
Cdd:PRK12853 432 VEAAWRIVDPVLDAWAADPVPPHEYPAGSWGPAAADALL 470
|
|
| G6PD_C |
pfam02781 |
Glucose-6-phosphate dehydrogenase, C-terminal domain; |
598-875 |
4.43e-68 |
|
Glucose-6-phosphate dehydrogenase, C-terminal domain;
Pssm-ID: 460694 Cd Length: 295 Bit Score: 228.09 E-value: 4.43e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 598 IFNRKYIRSVHILLKEEIGSFGR-DYFESYGIIRDMIQNHGMQLLSLIAMhcEhkkhlPQNKFS----------VLKCVR 666
Cdd:pfam02781 13 LWNRNYIDHVQITVAETLGVEGRgGYYDQAGALRDMVQNHLLQLLALVAM--E-----PPVSFDaedirdekvkVLRSLR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 667 TVQLSDL----VIGQYSESEKG----CSYRAEKGVPKDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAF 738
Cdd:pfam02781 86 PITPEDVednvVRGQYGAGWIGgepvPGYREEEGVPPDSRTETFAALKLFIDNWRWAGVPFYLRTGKRLPERVTEIRIQF 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 739 KcDPPKDI---CYDFVPTHLVYRIQPQPSVFWRKdftEVKV-GEVKDSYASDLEnekyFNTEEkilvdveasAAKRTIEG 814
Cdd:pfam02781 166 K-DVPHNLfrdPGTLPPNELVIRIQPDEGIYLKF---NAKVpGLGMRLRPVELD----FSYSD---------RFGERIPE 228
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 85001069 815 AYELLFFYAFSNKRDIFPTIKQVNEAWRIFTPVLEEISEKKVEPflYPRGSPGPKEADALL 875
Cdd:pfam02781 229 AYERLLLDVMRGDQTLFVRSDEVEAAWRIVDPILEAWDEEKPPP--YPAGSWGPKAADELL 287
|
|
| PRK12854 |
PRK12854 |
glucose-6-phosphate 1-dehydrogenase; Provisional |
394-876 |
6.84e-59 |
|
glucose-6-phosphate 1-dehydrogenase; Provisional
Pssm-ID: 237234 [Multi-domain] Cd Length: 484 Bit Score: 209.12 E-value: 6.84e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 394 TFILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEFFSqisndifssintniFIRNpairfdfpsVIT 473
Cdd:PRK12854 13 VFVLFGATGDLAKRKLLPGLFHLARAGLLPPDWRIVGTGRGDVSAEAFRE--------------HARD---------ALD 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 474 EFKSRCsriclkyDDSSFFDRFTEKVR-----------------------EIDRNSVTSHrmvYLATPSEAYQNILRVVt 530
Cdd:PRK12854 70 EFGARK-------LDDGEWARFAKRLRyvpggflsagpgalaaavaaaraELGGDARLVH---YLAVPPSAFLDVTRAL- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 531 scckPENGWF---RVMLEKPFGRDLKSCEEIDRFLSDHVAPDETFLVDHYLGKPVVSCILSSKISTK-YSRIFNRKYIRS 606
Cdd:PRK12854 139 ----GEAGLAegsRVVMEKPFGTDLASAEALNAAVHEVFDESQIFRIDHFLGKEAAQNILAFRFANGlFEPIWNREFIDH 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 607 VHILLKEEIGSFGR-DYFESYGIIRDMIQNHGMQLLSLIAMhcE-----HKKHLPQNKFSVLKCVRTVQLSDLVIGQYSe 680
Cdd:PRK12854 215 VQIDVPETLGVDTRaAFYDATGAYRDMVVTHLFQVLAFVAM--EpptalEPDAISEEKNKVFRSMRPLDPAEVVRGQYS- 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 681 sekgcSYRAEKGVPKDSLCATYCTVVLWVDNEDWEGVPFVITSGKGLEDKLVEIRLAFKcDPPKDI-----CYDFVPTHL 755
Cdd:PRK12854 292 -----GYRDEPGVAPDSTTETFVALKVWIDNWRWAGVPFYLRTGKRMAEGQRIISIAFR-EPPYSMfpagsVGAQGPDHL 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 756 VYRIQPQPSVFWrkDFTEVKVGEvkdsyASDLEN-EKYFNTEEkilvdveaSAAKRTIEGAYELLFFYAFSNKRDIFPTI 834
Cdd:PRK12854 366 TFDLADNSKVSL--SFYGKRPGP-----GMRLDKlSLQFSLKD--------TGPKGDVLEAYERLILDALRGDHTLFTTA 430
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 85001069 835 KQVNEAWRIFTPVLEEISEKKvepfLYPRGSPGPKEADALLS 876
Cdd:PRK12854 431 DGIESLWEVSQPLLEDPPPVK----PYAPGSWGPNAIHQLAA 468
|
|
| 6PGL |
cd01400 |
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ... |
107-370 |
1.03e-52 |
|
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.
Pssm-ID: 238694 [Multi-domain] Cd Length: 219 Bit Score: 183.15 E-value: 1.03e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 107 EGFVLTASHLILHKIRRKLSKspDVTVKIGLSGGSTPRGIYRFLGNMKDldIDFNRIIFFLVDERYVPSDDEMSNIRLLR 186
Cdd:cd01400 1 EALAEALADRIAEALAAAIAK--RGRFSLALSGGSTPKPLYELLAAAPA--LDWSKVHVFLGDERCVPPDDPDSNYRLAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 187 NTLLKHWPVPESNLVFPDTSLPLEECVKKYEADLEAVFGVVTthvnsntdpahrvagksemsstefesfdhsfykpkysi 266
Cdd:cd01400 77 EALLSHVAIPAANIHPIPTELGPEDAAAAYEKELRALFGGVP-------------------------------------- 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 267 VPDLVTLGIGEDFHIAGLFPEylstlDSSYVTDTLHRVMATYTETTVVRERISCSLPFLSCAPTKLFFLKGERKKRIWNT 346
Cdd:cd01400 119 PFDLVLLGMGPDGHTASLFPG-----HPALLEETDRLVVAVTDSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEALKR 193
|
250 260
....*....|....*....|....
gi 85001069 347 MLQYRhyDPIRFPATQIFTKPGCI 370
Cdd:cd01400 194 ALAGP--DPEELPAARVLPRPGEV 215
|
|
| G6PD_N |
pfam00479 |
Glucose-6-phosphate dehydrogenase, NAD binding domain; |
396-583 |
1.49e-44 |
|
Glucose-6-phosphate dehydrogenase, NAD binding domain;
Pssm-ID: 459827 [Multi-domain] Cd Length: 178 Bit Score: 158.74 E-value: 1.49e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 396 ILFGSGGDLARRKIYPALFHLFYLGFLPHKFHILAISRSHIDFEEFFSQISndifSSINTNIFIRnpairfdfPSVITEF 475
Cdd:pfam00479 1 VIFGATGDLAKRKLFPALYNLYRDGLLPEGFRIIGVARRDLSDEEFRERVR----EALKEFKELD--------EEKWDRF 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 476 KSRCSRICLKYDDSSFFDRFTEKVREIDrNSVTSHRMVYLATPSEAYQNI-LRVVTSCCKPENGWFRVMLEKPFGRDLKS 554
Cdd:pfam00479 69 LERLHYVSGDFDDPESYEKLKERLEEHE-DETRGNRLFYLAVPPSLFGPIaENLGRAGLSEEGGWRRVVIEKPFGHDLES 147
|
170 180
....*....|....*....|....*....
gi 85001069 555 CEEIDRFLSDHVAPDETFLVDHYLGKPVV 583
Cdd:pfam00479 148 ARELNDQLAKVFKEEQIYRIDHYLGKETV 176
|
|
| Glucosamine_iso |
pfam01182 |
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; |
105-373 |
7.38e-38 |
|
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
Pssm-ID: 460101 [Multi-domain] Cd Length: 222 Bit Score: 141.22 E-value: 7.38e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 105 TEEGFVLTASHLILHKIRRKLSKSPDVTvkIGLSGGSTPRGIYRFLGNMKDlDIDFNRIIFFLVDERYVPSDDEMSNIRL 184
Cdd:pfam01182 2 DAEALAQALAERLAEALEAALAERGRFT--LALSGGSTPKPLYELLAAAPA-RLDWSRVHVFWGDERCVPPDDPDSNYGM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 185 LRNTLLKHWPVPESNLV-FPDTSLPLEECVKKYEADLEAVFGvvtthvnSNTDPahrvagksemsstefesfdhsfykpk 263
Cdd:pfam01182 79 AREALLSHVPIPASNVHpIPASAADPEEAAAAYEAELRELLP-------DLELP-------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 264 ysiVPDLVTLGIGEDFHIAGLFPeylstlDSSYVTDTLHRVMATYTETTVVRERISCSLPFLSCAPTKLFFLKGERKKRI 343
Cdd:pfam01182 126 ---VFDLVLLGMGPDGHTASLFP------GSPALEETDRLVVAVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADA 196
|
250 260 270
....*....|....*....|....*....|
gi 85001069 344 WNTMLQyrhYDPIRFPATQIFtkPGCIAVL 373
Cdd:pfam01182 197 LRRALA---GDPDPLPAALVR--PGAGETV 221
|
|
| NagB |
COG0363 |
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ... |
103-374 |
1.95e-32 |
|
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440132 [Multi-domain] Cd Length: 248 Bit Score: 126.43 E-value: 1.95e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 103 CHTEEGFVLTASHLILHKIRRKLSKSPDVTvkIGLSGGSTPRGIYRFLGNM-KDLDIDFNRIIFFLVDERY-VPSDDEMS 180
Cdd:COG0363 7 FPDAEELAAAAAERAAERIAEAIAEKGRAV--LGLAGGSTPLGLYEELARLhKEGGLDWSRVHVFNLDEYVgLPPDHPQS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 181 NIRLLRNTLLKHWPVPESNLVFPDTSL--PLEECvKKYEADLEAVFGVvtthvnsntdpahrvagksemsstefesfdhs 258
Cdd:COG0363 85 NRRFMREALLDHVDIPPENIHIPDGEAedPEAAA-ARYEALIAEAGGI-------------------------------- 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 259 fykpkysivpDLVTLGIGEDFHIAGLFPeylstlDSSYVTDTLHRVMATY-----------TETTVVRERISCSLPFLSC 327
Cdd:COG0363 132 ----------DLQLLGIGEDGHIAFNFP------GSPFLSETDRVVTLDEstrqanarffgSIPKVPPQAITLGIPTIMK 195
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 85001069 328 APTKLFFLKGERKKRIWNTMLQyrhyDPI--RFPATQIFTKPGCIAVLD 374
Cdd:COG0363 196 AREILLLATGENKAEAVAAALE----GPVteEVPASILQGHPNVTWFLD 240
|
|
| pgl |
TIGR01198 |
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ... |
116-381 |
1.10e-26 |
|
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273494 [Multi-domain] Cd Length: 233 Bit Score: 109.39 E-value: 1.10e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 116 LILHKIRRKLSKSPDVTvkIGLSGGSTPRGIYRFLGnmkDLDIDFNRIIFFLVDERYVPSDDEMSNIRLLRNTLLKHWPV 195
Cdd:TIGR01198 15 RIATKLQTALAERGQFS--LALSGGRSPIALLEALA---AQPLDWSRIHLFLGDERYVPLDHADSNTGLAREALLDRVAI 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 196 PESNLVFPDTSLPL-EECVKKYEADLeavfgvvtthvnsntdpahrvagksemsstefesfdHSFYKPKYSIVPDLVTLG 274
Cdd:TIGR01198 90 PASNIHPMPTELSDiEEAAELYEQEL------------------------------------AAAFQPIVFPVFDLLLLG 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 275 IGEDFHIAGLFPEylstldSSYVTDTLHRVMATYTETTVVRERISCSLPFLSCAPTKLFFLKGERKKRIWNTMLQYRHyD 354
Cdd:TIGR01198 134 MGPDGHTASLFPH------TPALQETERLVTVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAVEA-E 206
|
250 260
....*....|....*....|....*..
gi 85001069 355 PIRFPATQIFTKPGCIAVLDSSTIRKV 381
Cdd:TIGR01198 207 PYPLPAAGVLHSGKTLWLLDYAAARKL 233
|
|
| GlcN6P_deaminase |
cd01399 |
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ... |
113-294 |
9.82e-15 |
|
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.
Pssm-ID: 238693 [Multi-domain] Cd Length: 232 Bit Score: 74.44 E-value: 9.82e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 113 ASHLILHKIRRKLSKSPDVTvkIGLSGGSTPRGIYRFLGNM-KDLDIDFNRIIFFLVDErYV--PSDDEMSNIRLLRNTL 189
Cdd:cd01399 3 MSEAAAELIAELIREKPPAV--LGLATGSTPLGVYEELIELhKEGGLSFSNVTTFNLDE-YVglPPDHPQSYHYFMRENL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 190 LKHWPVPESNLVFPD--TSLPLEECvKKYEADLEAVFGVvtthvnsntdpahrvagksemsstefesfdhsfykpkysiv 267
Cdd:cd01399 80 FDHIDIKPENIHIPDgnAADLEAEC-RRYEALIAEAGGI----------------------------------------- 117
|
170 180
....*....|....*....|....*..
gi 85001069 268 pDLVTLGIGEDFHIAglFPEYLSTLDS 294
Cdd:cd01399 118 -DLQLLGIGENGHIG--FNEPGSSLDS 141
|
|
| SugarP_isomerase |
cd00458 |
SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate ... |
117-223 |
1.69e-12 |
|
SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium, the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate. 6PGL converts 6-phosphoglucono-1,5-lactone to 6-phosphogluconate, the second step of the oxidative phase of the pentose phosphate pathway.
Pssm-ID: 238258 Cd Length: 169 Bit Score: 66.61 E-value: 1.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 117 ILHKIRRKLSKSPDVTVK--IGLSGGSTPRGIYRFLGNMKDLDiDFNRIIFFLVDERYVPSDDEMSNIRLLRNTLLKHWP 194
Cdd:cd00458 4 ALKFIEDK*EKLLEEKDDmvIGLGTGSTPAYFYKLLGEKLKRG-EISDIVGFPTDERYVPLDSDQSNFRQAKLLAFEHDI 82
|
90 100 110
....*....|....*....|....*....|
gi 85001069 195 VPESNLVFPDTSLPLEE-CVKKYEADLEAV 223
Cdd:cd00458 83 IPASNVHYVDTSLPIEKaCEKYEREILDQV 112
|
|
| nagB |
PRK00443 |
glucosamine-6-phosphate deaminase; Provisional |
113-315 |
7.57e-12 |
|
glucosamine-6-phosphate deaminase; Provisional
Pssm-ID: 179028 [Multi-domain] Cd Length: 261 Bit Score: 66.39 E-value: 7.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 113 ASHLILHKIRRKLSKSPDVTVkIGLSGGSTPRGIYRFLGNM-KDLDIDFNRIIFFLVDErYV--PSDDEMSNIRLLRNTL 189
Cdd:PRK00443 16 AARHIANRINAFLPTKERPFV-LGLATGSSPLETYKALIELhKAGKVDFSRVTTFNLDE-YVglPADHPESYRYFMRENF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 190 LKHWPVPESNLVFPD--TSLPLEECvKKYEADLEAVFGVvtthvnsntdpahrvagksemsstefesfdhsfykpkysiv 267
Cdd:PRK00443 94 FDHVDIPPENINLLNgnAPDPEAEC-RRYEEKIKSAGGI----------------------------------------- 131
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 85001069 268 pDLVTLGIGEDFHIAglFPEYLSTLDSSYVTDTLhrvmatyTETTVVR 315
Cdd:PRK00443 132 -DLQILGIGENGHIA--FNEPGSSFASRTRIKTL-------TEDTRIA 169
|
|
| PLN02360 |
PLN02360 |
probable 6-phosphogluconolactonase |
135-340 |
2.13e-08 |
|
probable 6-phosphogluconolactonase
Pssm-ID: 166001 [Multi-domain] Cd Length: 268 Bit Score: 56.41 E-value: 2.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 135 IGLSGGStprgIYRFLGNM----KDLDIDFNRIIFFLVDERYVPSDDEMSNIRLLRNTLLKHWPVPESNLVFPDTSLPLE 210
Cdd:PLN02360 46 IALSGGS----LISFMGKLceapYNKTVDWAKWYIFWADERVVAKNHADSNYKLAKDGLLSKVPVVPSHVYSINDTVTAE 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 211 ECVKKYEADLEAVFGVVTTHVNSNTDpahrvagksemsstefesfdhsfyKPKYsivpDLVTLGIGEDFHIAGLFPEYlS 290
Cdd:PLN02360 122 EAATDYEFAIRQLVKTRTIGVSDISD------------------------CPKF----DLILLGMGSDGHVASLFPNH-P 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 85001069 291 TLDS-----SYVTDTlhrvmatyteTTVVRERISCSLPFLSCAPTKLFFLKGERK 340
Cdd:PLN02360 173 ALEEkddwvTFITDS----------PKPPPERITFTLPVINSASNVAVVATGESK 217
|
|
| PRK02122 |
PRK02122 |
glucosamine-6-phosphate deaminase-like protein; Validated |
112-276 |
7.66e-08 |
|
glucosamine-6-phosphate deaminase-like protein; Validated
Pssm-ID: 235005 [Multi-domain] Cd Length: 652 Bit Score: 56.19 E-value: 7.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 112 TASHLILHKI------RRKLSKspdvTVKIGLSGGSTPRGIYRFLGNM-KDLDIDFNRIIFFLVDERY-VPSDDEMSNIR 183
Cdd:PRK02122 38 EASRAVAQEIatlireRQAEGK----PCVLGLATGSSPIGVYAELIRMhREEGLSFKNVITFNLDEYYpMQPDSLQSYHR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 184 LLRNTLLKHWPVPESNLVFPDTSLPLEE----CvKKYEADLEAV-----------------FGVVTTHVNSNT-----DP 237
Cdd:PRK02122 114 FMKENLFDHVDIPPENIHIPDGTIPKEEideyC-RDYEEKIEAAggidfqllgigrtghigFNEPGSGRNSRTrlvtlDH 192
|
170 180 190
....*....|....*....|....*....|....*....
gi 85001069 238 AHRVAgksemSSTEFESFDHSfykPKYSIvpdlvTLGIG 276
Cdd:PRK02122 193 ITRRD-----AASDFFGEENV---PRKAI-----TMGVG 218
|
|
| PTZ00285 |
PTZ00285 |
glucosamine-6-phosphate isomerase; Provisional |
77-294 |
6.51e-06 |
|
glucosamine-6-phosphate isomerase; Provisional
Pssm-ID: 140308 Cd Length: 253 Bit Score: 48.60 E-value: 6.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 77 MNIVLSAKSDGFDEYddvlfepclldchteegfvltASHLILHKIR--RKLSKSPDVtvkIGLSGGSTPRGIYRFLGNM- 153
Cdd:PTZ00285 1 MRIVISEDADAVADY---------------------TSNYIIKRINdfKPTSDRPFV---LGLPTGSTPLPTYQELIRAy 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85001069 154 KDLDIDFNRIIFFLVDErYV--PSDDEMSNIRLLRNTLLKHWPVPESNLVFPDTSLP--LEECvKKYEADLEAVFGVvtt 229
Cdd:PTZ00285 57 REGRVSFSNVVTFNMDE-YVglPRDHPQSYHYFMKENFFDHVDIKEENRHILNGTAPdlEEEC-RRYEEKIRAVGGI--- 131
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 85001069 230 hvnsntdpahrvagksemsstefesfdhsfykpkysivpDLVTLGIGEDFHIAglFPEYLSTLDS 294
Cdd:PTZ00285 132 ---------------------------------------DLFLAGIGTDGHIA--FNEPGSSLDS 155
|
|
| |
