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Conserved domains on  [gi|187250396|ref|YP_001874815|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Mecistops cataphractus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.29e-113

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 333.71  E-value: 1.29e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   1 MPIFQPIILTTLTITTFIFLSSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITT 80
Cdd:MTH00112   2 NPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  81 GNCQIMEMTNQTLMIIMILAMFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVNFEVISVVSILS 160
Cdd:MTH00112  82 GQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITS 240
Cdd:MTH00112 162 TLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLN 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 241 SLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPNATNTKRLWRKSTQQ 320
Cdd:MTH00112 242 TTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKK 321

                        330       340
                 ....*....|....*....|....*.
gi 187250396 321 TNLTiNSMATAAMTLILAATLMKAIT 346
Cdd:MTH00112 322 NTLT-ATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.29e-113

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 333.71  E-value: 1.29e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   1 MPIFQPIILTTLTITTFIFLSSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITT 80
Cdd:MTH00112   2 NPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  81 GNCQIMEMTNQTLMIIMILAMFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVNFEVISVVSILS 160
Cdd:MTH00112  82 GQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITS 240
Cdd:MTH00112 162 TLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLN 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 241 SLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPNATNTKRLWRKSTQQ 320
Cdd:MTH00112 242 TTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKK 321

                        330       340
                 ....*....|....*....|....*.
gi 187250396 321 TNLTiNSMATAAMTLILAATLMKAIT 346
Cdd:MTH00112 322 NTLT-ATLTTLSTLLLPLSPMILTII 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 21-295 6.11e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.26  E-value: 6.11e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIA-NKSHPRAIEASTKYFLTQATASALMIF--------SGTLNYITTGNCQIMEMTNQ 91
Cdd:COG1007  120 SANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygaTGSLNLAGIAAALAAGGANS 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  92 TLMII----MILAMFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLF-----LMSPLVNF--EVISVVSILS 160
Cdd:COG1007  200 PLLLLglvlVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLrllveAFPGLAADwqLLLAVLAVLS 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 161 VTVAGWLGLNQTQIRKLVALSSIAQM--AWTVIIIKYAPSLTILAFY--VYSIT-----ISTTLLTLEKLSTTSVSSLLL 231
Cdd:COG1007  280 MTVGNLAALAQTNVKRMLAYSSIAHAgyLLLGLAAGTPLGVSAALFYllAYLFMnlgafAVILLLSRKGGEAEEIEDLAG 359

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 187250396 232 SFSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:COG1007  360 LARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 22-285 1.68e-17

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 81.59  E-value: 1.68e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   22 STHLVLMWVSLELSTLVVLPLIA-NKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLM------ 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   95 -----IIMILAMFIKVGLVPFHFWVPETIQGMSPTASIFLL-TWQKLGPLIL---LFLMSPLVNF--EVISVVSILSVTV 163
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLirrSLLYLPSSPFiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  164 AGWLGLNQTQIRKLVALSSIAQMAWTVIII----KYAPSLTILAFYVYSITISTTLL-----TLEKLSTTSVSSLLLSFS 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 187250396  235 KAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMAS 285
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 21-295 8.78e-16

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 78.07  E-value: 8.78e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   21 SSTHLVLMWVSLELSTLVVLPLIA-NKSHPRAIEASTKYFLTQATASALMIF--------SGTLNYITTGNCQIMEMTNQ 91
Cdd:TIGR01770 120 SSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFgisliygfTGSLNFEDLLLFLSNGMLNI 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   92 TLMII----MILAMFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLF--LMSPLVNF-----EVISVVSILS 160
Cdd:TIGR01770 200 SLLLLgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlFLYILFGFseawqIFLAIIAFLS 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTVIIIK-------YAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLL-- 231
Cdd:TIGR01770 280 MLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLagtlegiKAVLFYIFIYALMSLGAFGVLSLLRSYKDEWIEYISDfa 359

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 187250396  232 -SFSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:TIGR01770 360 gLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.29e-113

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 333.71  E-value: 1.29e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   1 MPIFQPIILTTLTITTFIFLSSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITT 80
Cdd:MTH00112   2 NPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  81 GNCQIMEMTNQTLMIIMILAMFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVNFEVISVVSILS 160
Cdd:MTH00112  82 GQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITS 240
Cdd:MTH00112 162 TLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLN 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 241 SLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPNATNTKRLWRKSTQQ 320
Cdd:MTH00112 242 TTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKK 321

                        330       340
                 ....*....|....*....|....*.
gi 187250396 321 TNLTiNSMATAAMTLILAATLMKAIT 346
Cdd:MTH00112 322 NTLT-ATLTTLSTLLLPLSPMILTII 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 21-335 2.94e-78

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 243.56  E-value: 2.94e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMIIMILA 100
Cdd:MTH00135  22 ASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMSHPLPTTMITLA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 101 MFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPlVNFEVISVVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00135 102 LALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAP-TNPTLLITLGLTSTLVGGWGGLNQTQLRKILAY 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 181 SSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00135 181 SSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFM 260

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 187250396 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPNATNTKRLWRKSTQQTNLTINSMATAAMTL 335
Cdd:MTH00135 261 PKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQLTLPLAISTTATLML 335
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 21-342 4.83e-78

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 242.90  E-value: 4.83e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMIIMILA 100
Cdd:MTH00070  22 SSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFTGEWTIMNMQTPLPTIMLTIA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 101 MFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVNFEVISVVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00070 102 LMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLSTLIGGWGGLNQTQLRKIMAY 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 181 SSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00070 182 SSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLGGLPPTTGFI 261

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPNATNTKRLWRKSTQQTNLTINSMATAAMTLILAAT 340
Cdd:MTH00070 262 PKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNKTNNLLSLTIILSLMLLPITPT 341


                 ..
gi 187250396 341 LM 342
Cdd:MTH00070 342 IL 343
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 21-342 3.06e-75

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 235.90  E-value: 3.06e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMIIMILA 100
Cdd:MTH00105  22 ISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTITKLTNPTASTLMTIA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 101 MFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVNFEVISVVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00105 102 LAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSILIGGWGGLNQTQLRKILAY 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 181 SSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00105 182 SSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLGGLPPLTGFM 261

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPNATNTKRLWR-KSTQQTNLTINSMATAAMTLILAA 339
Cdd:MTH00105 262 PKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQfENTKPMTLLPTLIILSTMLLPLTP 341


                 ...
gi 187250396 340 TLM 342
Cdd:MTH00105 342 MLS 344
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 21-342 7.51e-66

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 211.75  E-value: 7.51e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMIIMILA 100
Cdd:MTH00200  22 SSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWGISEMLGPLSETLILLA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 101 MFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVNFEVISVVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00200 102 LALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLSVLVGGWGGLNQTQLRKILAY 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 181 SSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00200 182 SSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSLGGLPPLTGFF 261

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPNATNTKRLWRKSTQQTNLTINSMATAAMTLILAAT 340
Cdd:MTH00200 262 PKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSNSNLLVGLLLLLSILGLPLTPQ 341


                 ..
gi 187250396 341 LM 342
Cdd:MTH00200 342 LL 343
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 21-325 4.17e-61

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 199.39  E-value: 4.17e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMIIMILA 100
Cdd:MTH00041  22 SSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNTLSSIIITLA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 101 MFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVNFEVISVVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00041 102 LALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQTQTRKILAF 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 181 SSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00041 182 SSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLTGFL 261

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 187250396 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPNATNTKRLWRKSTQQTNLTI 325
Cdd:MTH00041 262 NKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGV 326
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 21-299 4.35e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 141.50  E-value: 4.35e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYIttgncqIMEMTNQTLMIIMILA 100
Cdd:MTH00160  23 SSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML------NLMLFNNISSMLINSS 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 101 MFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMsplVNFEVISVVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00160  97 LLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIILSAIIGAIGGLNQTSLRKILAY 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 181 SSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00160 174 SSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGFL 253

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 187250396 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNS 299
Cdd:MTH00160 254 PKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSS 292
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 21-314 2.69e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 136.55  E-value: 2.69e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNcqimemtnQTLMIIMILA 100
Cdd:MTH00144  22 SSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFS--------WFSMSLLLLG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 101 MFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVN-FEVISVVSILSVTVAGWLGLNQTQIRKLVA 179
Cdd:MTH00144  94 LCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWlAYLLCVISVLSALVGSIGGLNQTQVRALLA 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 180 LSSIAQMAWTVIIIKYAPSLTILAFYVYSItISTTLLTLEKLSTTSVSSLLLSFSKAPITSSLLTISLLSLSGLPPLAGF 259
Cdd:MTH00144 174 YSSISHTGWMLVAILHGSWLMWMYFLIYIV-SSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLLLSLGGLPPFLGF 252

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 187250396 260 LPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPNATNTKRLW 314
Cdd:MTH00144 253 CSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 21-336 4.50e-35

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 130.67  E-value: 4.50e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGncqimeMTNQTLMIIMILA 100
Cdd:MTH00011  24 SSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPS------LLKNITALMLLVS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 101 MFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVNFEVISVVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00011  98 LMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQLRPLLAY 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 181 SSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00011 178 SSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPFTGFM 257

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 187250396 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPpnatNTKRLWRKSTQQTNLTINSMATAAMTLI 336
Cdd:MTH00011 258 PKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSP----TFSSLKSAPYEPKTKILISMCTLSLGLI 329
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 21-299 5.83e-34

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 127.48  E-value: 5.83e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLnyittgnCQIMEMTNQTLMIIMILA 100
Cdd:MTH00197  16 SSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSL-------SFSNLYLSLLSVVLVILG 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 101 MFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPlvNFEVISVVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00197  89 LLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS--SFMGLLICSVLSSLIGGIGGMNQSNIRQLLAY 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 181 SSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00197 167 SSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLPPLSGFF 246

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 187250396 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNS 299
Cdd:MTH00197 247 LKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 21-295 6.11e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.26  E-value: 6.11e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIA-NKSHPRAIEASTKYFLTQATASALMIF--------SGTLNYITTGNCQIMEMTNQ 91
Cdd:COG1007  120 SANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygaTGSLNLAGIAAALAAGGANS 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  92 TLMII----MILAMFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLF-----LMSPLVNF--EVISVVSILS 160
Cdd:COG1007  200 PLLLLglvlVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLrllveAFPGLAADwqLLLAVLAVLS 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 161 VTVAGWLGLNQTQIRKLVALSSIAQM--AWTVIIIKYAPSLTILAFY--VYSIT-----ISTTLLTLEKLSTTSVSSLLL 231
Cdd:COG1007  280 MTVGNLAALAQTNVKRMLAYSSIAHAgyLLLGLAAGTPLGVSAALFYllAYLFMnlgafAVILLLSRKGGEAEEIEDLAG 359

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 187250396 232 SFSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:COG1007  360 LARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
21-295 5.15e-19

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 87.57  E-value: 5.15e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIA-NKSHPRAIEASTKYFLTQATASALMIF--------SGTLNYITTGNCQIMEMTNQ 91
Cdd:PRK05777 121 SANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygaTGSLSFAGIAKALADGSGNS 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  92 TLMII----MILAMFIKVGLVPFHFWVPETIQGmSPTASI-FLLTWQKL---GPLILLFLMSPL----VNFEVISVVSIL 159
Cdd:PRK05777 201 LLLLFglvfLLVGLAFKLSAVPFHMWTPDVYEG-APTPVTaFLATAPKIaafAVLLRLLVVAFGglseDWQQVLAIIAIA 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 160 SVTVAGWLGLNQTQIRKLVALSSIAQM--AWTVIIIKYAPSLTILAFY--VYSIT-----ISTTLLTLEKLSTTSVSSLL 230
Cdd:PRK05777 280 SMLVGNLAALSQTNIKRLLAYSSIAHAgyLLVGLAAGTAEGYSAVLFYllAYLFMtlgafGVISLLRRKGGEAESISDFA 359

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 187250396 231 LSFSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:PRK05777 360 GLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 21-295 2.44e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 85.08  E-value: 2.44e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIA-NKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQI--------MEMTNQ 91
Cdd:MTH00196  11 SSSNWLSVYLAIELQTLSLFILIAqNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLsyinlvlnSGQSFS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  92 TLMI-----IMILAMFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPlvNFEVISVVSILSVTVAGW 166
Cdd:MTH00196  91 SVSVpigylLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL--NVNILLIGGLFSLFVGAI 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 167 LGLNQTQIRKLVALSSIAQMAWTVI------IIKYAPSLTILAFYVY-SITISTTLLTLeKLSTTSVSSLLLSFSKAPIT 239
Cdd:MTH00196 169 GALNQTKIKRLLAYSGIGHMGFVLWgieigsFESIQASLVYLFIYIImSICVFSIILAL-NVYKNLIIEFSGLSRRLPIL 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 187250396 240 SSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:MTH00196 248 AITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 22-285 1.68e-17

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 81.59  E-value: 1.68e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   22 STHLVLMWVSLELSTLVVLPLIA-NKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLM------ 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   95 -----IIMILAMFIKVGLVPFHFWVPETIQGMSPTASIFLL-TWQKLGPLIL---LFLMSPLVNF--EVISVVSILSVTV 163
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLirrSLLYLPSSPFiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  164 AGWLGLNQTQIRKLVALSSIAQMAWTVIII----KYAPSLTILAFYVYSITISTTLL-----TLEKLSTTSVSSLLLSFS 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 187250396  235 KAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMAS 285
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 21-295 8.78e-16

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 78.07  E-value: 8.78e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   21 SSTHLVLMWVSLELSTLVVLPLIA-NKSHPRAIEASTKYFLTQATASALMIF--------SGTLNYITTGNCQIMEMTNQ 91
Cdd:TIGR01770 120 SSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFgisliygfTGSLNFEDLLLFLSNGMLNI 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   92 TLMII----MILAMFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLF--LMSPLVNF-----EVISVVSILS 160
Cdd:TIGR01770 200 SLLLLgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlFLYILFGFseawqIFLAIIAFLS 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTVIIIK-------YAPSLTILAFYVYSITISTTLLTLEKLSTTSVSSLLL-- 231
Cdd:TIGR01770 280 MLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLagtlegiKAVLFYIFIYALMSLGAFGVLSLLRSYKDEWIEYISDfa 359

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 187250396  232 -SFSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:TIGR01770 360 gLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 21-295 5.38e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 75.82  E-value: 5.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHP-RAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIME----MTNQTLMI 95
Cdd:MTH00199 115 SSINWLSIYLAIELQTLTLFILVALKRDSaYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGinsiLTGDVGKI 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  96 IMILAMFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVNFEVISVVsiLSVTVAGWLGLNQTQIR 175
Cdd:MTH00199 195 LITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAV--LSIIYGAIGALNQTKIK 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 176 KLVALSSIAQMAWTVIIIKYAPSLTILAFYVY-------SITISTTLLTLeKLSTTSVSSLLLSFSKAPITSSLLTISLL 248
Cdd:MTH00199 273 RLLAYSGIGHMGFILFGVAIGSFESIQASLIYmiiyvimSICSFSIILSL-KLTKGLIVEVSGLSRKNPVIALTLALTFL 351

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 187250396 249 SLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:MTH00199 352 SIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 22-297 3.44e-12

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 67.09  E-value: 3.44e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  22 STHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIF--------SGTLNY--ITTGNCQIMEMTNQ 91
Cdd:COG0651  126 TGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLgvgllygaTGTLNMadLAARLAELDPGLLL 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  92 TLMIIMILAMFIKVGLVPFHFWVPET-IQGMSPTASIF--LLTwqKLGPLILL---FLMSPLVNFE----VISVVSILSV 161
Cdd:COG0651  206 AAFALLLVGFGIKAALFPLHFWLPDAyPAAPSPVSALLsgLLT--KVGVYAILrvlTLLFGADPALflgtLLLVLGLLTM 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 162 TVAGWLGLNQTQIRKLVALSSIAQMAWTVIIIKYAPSLTILA--FYVYSITISTTLL------TLEKLSTTSVSSLLLSF 233
Cdd:COG0651  284 LVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGalFHLLNHALAKALLflaagaIERATGTRDLDKLGGLG 363

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 187250396 234 SKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWY 297
Cdd:COG0651  364 KRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFG 427
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 28-297 1.23e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 62.59  E-value: 1.23e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  28 MWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTN--------QTLMIIMIL 99
Cdd:PRK08375 131 LFVFLEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGalaenptvVTAFGFVLL 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 100 AMFIKVGLVPFHFWVPETIQGMSPTASIFL-LTWQKLG--PLILLFL-------MSPLVNFEVISVVSILSVTVAGWLGL 169
Cdd:PRK08375 211 ALALKAAVFPLHTWLPRAYPAAPPVVTALLsGLVTKVAvyALIRIYFtvfggdfRFALGLGWLLAVLALLSMLVGSLAAL 290

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 170 NQTQIRKLVALSSIAQMAWTVIIIKYAPSLTILA--FYV--YSITISTTLLTL----EKLSTTSVSSLLLSFSKAPITSS 241
Cdd:PRK08375 291 GQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAglLHLlhHALMKGALFLAAgaieVTYGTRRLSELSGLGRRMPLTAA 370

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 187250396 242 LLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWY 297
Cdd:PRK08375 371 AFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 21-186 1.30e-09

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 59.18  E-value: 1.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFS---------GTLNYITTGNCQIMEMTNQ 91
Cdd:TIGR01972 124 LALDLFLFYVFWEAMLIPMYLLIGVWGGPNRIYAAMKFFLYTLAGSLLMLLAilglyflggGTFDLLELLNLPLPFGVQT 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396   92 TLMIIMILAMFIKVGLVPFHFWVPEtIQGMSPTASIFLL--TWQKLGPLILLFLMSPL-----VNF-EVISVVSILSVTV 163
Cdd:TIGR01972 204 WLFLAFFIAFAVKVPLFPLHTWLPD-AHVEAPTAGSVILagVLLKMGTYGFLRFNLPLfpdasLYFaPVLAALGVIAIIY 282

                         170       180
                  ....*....|....*....|...
gi 187250396  164 AGWLGLNQTQIRKLVALSSIAQM 186
Cdd:TIGR01972 283 GALIALAQTDIKRLIAYSSISHM 305
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 25-186 2.26e-07

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 52.39  E-value: 2.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  25 LVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFS----------GTLNYITTGNCQIMEMTNQTLM 94
Cdd:COG1008  133 LFLFYVFWELMLIPMYFLIGIWGGERRIYAAIKFFLYTLAGSLLMLVAilalyflagaLTFDIAELAAAPLPLTAQLLLF 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  95 IIMILAMFIKVGLVPFHFWVPETIQGMSPTASIFL---------------------LTWQKLGPLILlflmsplvnfeVI 153
Cdd:COG1008  213 LAFFIAFAVKVPMFPFHTWLPDAHVEAPTAGSVLLagvllkmggygllrfalplfpEASAYFAPLLA-----------AL 281

                        170       180       190
                 ....*....|....*....|....*....|...
gi 187250396 154 SVVSILsvtVAGWLGLNQTQIRKLVALSSIAQM 186
Cdd:COG1008  282 GVIGII---YGALVALAQTDLKRLIAYSSVSHM 311
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 21-186 1.03e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 47.12  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALM----IFSGTLNYITTGNCQI-------MEMT 89
Cdd:PRK05846 129 AALDLLLFYVFFEAMLIPMYFLIGVWGGKNRIYAATKFFLYTLLGSLLMlvaiIYLVVVYYNATGTFDIadllnlpLPPG 208

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  90 NQTLMIIMILAMF-IKVGLVPFHFWVPETiQGMSPTASIFLLT--WQKLGPLILLFLMSPL-----VNFE-VISVVSILS 160
Cdd:PRK05846 209 VQYWLFLAFFIAFaVKMPMFPLHTWLPDA-HVQAPTAGSVLLAgiLLKMGAYGLLRFSLPLfpdasHEFApIIITLGVIA 287

                        170       180
                 ....*....|....*....|....*.
gi 187250396 161 VTVAGWLGLNQTQIRKLVALSSIAQM 186
Cdd:PRK05846 288 IIYGALVALAQTDIKKLIAYSSISHM 313
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
22-294 1.60e-05

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 46.58  E-value: 1.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  22 STHLVLMWVSLE-LSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNY-ITTGNCQIMEM-----TNQTLM 94
Cdd:PRK02504 129 ATELVMIFISLEtLSIASYLLTGYMKRDPRSNEAALKYLLIGAASSAIFLYGSSLLYgLSGGSTQLSAIalaliTSPSLG 208

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  95 IIMILAMFI-----KVGLVPFHFWVPETIQGmSPTASI-FLLTWQKLG--PLILLFLMSPLVNFE-----VISVVSILSV 161
Cdd:PRK02504 209 LALALVFVIagiafKISAVPFHQWTPDVYEG-SPTPVVaFLSVGSKAAgfALAIRLLVTAFPSFDeqwklLFTALAILSM 287

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 162 TVAGWLGLNQTQIRKLVALSSIAQMAWTVIII------KYAPSLTILAFYVY---SITISTTLLTLeKLSTTSVSSLLLS 232
Cdd:PRK02504 288 VLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLvagteaGYASMVFYLLAYLFmnlGAFACVILFSL-RTGTDQISDYAGL 366

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 187250396 233 FSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLR 294
Cdd:PRK02504 367 YQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIR 428
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 22-218 1.83e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 46.29  E-value: 1.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  22 STHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATA------SALMIFSGTLNYITTGNCQIMEMTNQ---- 91
Cdd:PRK08676 121 SDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNWTELAAHasll 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  92 --TLMIIMILAMFI----KVGLVPFHFWVPETI----QGMSPTASIFLLTWQKLGPLILLFLMSPLVNFEVISVV----S 157
Cdd:PRK08676 201 spSVLGASFLFIFIgflaKSGLVPFHTWLPAAYakapSVVSALLSGTVLNIGIYGILRLSALLRQSGAAEQFSNVliglG 280

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 187250396 158 ILSVTVAGWLGLNQTQIRKLVALSSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTL 218
Cdd:PRK08676 281 IFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHMLAHSLVKSGL 341
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 22-186 2.38e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 45.91  E-value: 2.38e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  22 STHLVLMWVSLELSTLVVLPLIANKSH-PRAIEASTKYFLTQAT------ASALMIFS--GTLNYITTGNcQIMEMTNQT 92
Cdd:COG1009  130 SDNLLLLFVFWELVGLCSYLLIGFWYEkPSARRAARKAFLVTRVgdlgllLGILLLGAiaGTLNFSELLA-AAPTILSSP 208

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  93 LMIIMILAMFI----KVGLVPFHFWVPETIQGMSP-----------TASIFLLTwqKLGPLillFLMSPLVnFEVISVVS 157
Cdd:COG1009  209 LLTLILLLLLLgafgKSAQFPLHFWLPDAMEGPTPvsallhaatmvKAGVYLLA--RLSPL---FALSPVW-LTVVAIIG 282

                        170       180
                 ....*....|....*....|....*....
gi 187250396 158 ILSVTVAGWLGLNQTQIRKLVALSSIAQM 186
Cdd:COG1009  283 AITALFAALIALAQTDIKRVLAYSTVSQL 311
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 29-188 2.43e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 45.86  E-value: 2.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  29 WVSLELSTLVVLPLIANKSH-PRAIEASTKYFLTQATASALMIFS-----GTLNYITTGNCQIMEMTNQTLMIIMILAMF 102
Cdd:PRK08376 147 FVFLEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGiallyGQYGTLNMAYLAVKMSENPTVVAKIALALF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 103 I-----KVGLVPFHFWVPETiQGMSPTASIFLLTWQKLGPL-----ILLFLMSPLVNFE----VISVVSILSVTVAGWLG 168
Cdd:PRK08376 227 IaglamKSGAVPVHMWLPDA-YPAAPSSISAMLLVIKQAGLyalarVLFSIYGPAINLAtvgwVIIILGCLTMFVGVAMA 305

                        170       180
                 ....*....|....*....|
gi 187250396 169 LNQTQIRKLVALSSIAQMAW 188
Cdd:PRK08376 306 VVQKDVKRLLAYHSVSQIGY 325
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 22-297 3.54e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 45.37  E-value: 3.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  22 STHLVLMWVSLELSTLVVLPLIANKSHpRAIEASTKYFLTQATASALMIFS--------GTLNYITTGNCQIMEMTNQTL 93
Cdd:PRK08668 117 ANDLLTLYIFWEIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAifliyaktGTFDFADISQGLINDTSTGFA 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  94 MIIMIL---AMFIKVGLVPFHFWVPETiQGMSPTA--SIFLLTWQKLGPLILLFLMS-----------------PLVNFe 151
Cdd:PRK08668 196 LIVFLFllaFGVAKAGIFPLHVWAPDA-YSEAPQSfsAVLSGQLSKLGAYGFLLVLYvlpgtklfsefgtyrgvPLFNY- 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 152 VISVVSILSVTVAGWLGLNQTQIRKLVALSSIAQMAWTVIIIKYAPSLTILA--FYVYSITISTTLLTLEKLSTTSVSSL 229
Cdd:PRK08668 274 ILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAGglFHVFNHALFKGLFFLIFAAVIYRTGT 353

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 187250396 230 LLS------FSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWY 297
Cdd:PRK08668 354 TKIsemgglIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 22-295 3.74e-05

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 45.62  E-value: 3.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  22 STHLVLMWVSLELSTLVVLPLIANKSHPRAI---------EASTKYFLTQATASALMIFSGTLNYITTGN--------CQ 84
Cdd:MTH00198 207 SANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegmlgtilSA 286

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  85 IMEMTNQTL------MIIMILAMFIKVGLVPFHFWVPETIQGMSPTASIFLLTWQKLGPLILLflMSPLVNFEVISVVSI 158
Cdd:MTH00198 287 TLETTNIELrqgslgYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--TSLVITSKLLLSVAI 364

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 159 LSVTVAGWLGLNQTQIRKLVALSSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLL-------TLEKLSTTSVSS--- 228
Cdd:MTH00198 365 ISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTYLVSALasftvicTLEEFGTRTPTSrqr 444

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 229 ---------------LLLSFSKAPITSSLLTISLLSLSGLPPLAGFLPKW--------------LTIDQLVAEGAIWITF 279
Cdd:MTH00198 445 dgsfgnynlvrrlvdLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWfilvgsikiafsssLSIYYLVALFAIICTC 524

                        330
                 ....*....|....*.
gi 187250396 280 VmlmasllSLFFYLRL 295
Cdd:MTH00198 525 I-------SAFYYIRI 533
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 21-186 8.94e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 44.15  E-value: 8.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  21 SSTHLVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGN-----------CQIMEMT 89
Cdd:PRK06458 126 TSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTILVYANAATvmgdgemailwTELLKHA 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  90 NQTLMIIMILA---MFI----KVGLVPFHFWVPET-IQGMSPTASIF----------------LLTWQKLGPLILLFLMs 145
Cdd:PRK06458 206 SLLDPTLMKLAfvfLLIgfgtKVGLFPMHAWLPDAhSEAPSPVSALLsgvllnvalyavlryyILIDAAIGSDFPGRLL- 284

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 187250396 146 plvnfeviSVVSILSVTVAGWLGLNQTQIRKLVALSSIAQM 186
Cdd:PRK06458 285 --------LIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHM 317
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 28-195 3.54e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 42.51  E-value: 3.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  28 MWVSLELSTLVVLPLIANKSH-PRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMI--------IMI 98
Cdd:PRK12649 136 LFIFWELTSITSFMLIGYWRHrPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSELIenikghplFLI 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  99 LAMFIKVGLV------PFHFWVPETIQGMSPTASIFLLTWQKLGPLILLFLMSPLVN-----FEVISVVSILSVTVAGWL 167
Cdd:PRK12649 216 TLILIFIGAAaksaqgPFYIWLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIFSgteawFILVSGTGMITMVLAGFL 295

                        170       180
                 ....*....|....*....|....*...
gi 187250396 168 GLNQTQIRKLVALSSIAQMAWTVIIIKY 195
Cdd:PRK12649 296 AFRQTDIKAILAYSTISQLAYLMTMYGY 323
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
25-203 6.34e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 41.61  E-value: 6.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  25 LVLMWVSLELSTLVVLPLIANKSHPRAIEASTKYFLTQATASALMI--------FSGTLNY-ITTGNCQIMEMTNQTLMI 95
Cdd:PRK06473 129 LLLFFLFYELELIPLYLLIAIWGGQRRGYAATKFLLYTAISGILILvsflglvwLSGASSFdYEPLRSHTLPLSTQLLLL 208

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  96 IMILAMF-IKVGLVPFHFWVPET-IQGMSPTASIFLLTWQKLGPLILL------FLMSPLVNFEVISVVSILSVTVAGWL 167
Cdd:PRK06473 209 APILVGFgIKIPLVPFHTWLPDAhVEASTPVSVLLAGVLLKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASC 288

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 187250396 168 GLNQTQIRKLVALSSIAQMAWTVIIIKYAPSLTILA 203
Cdd:PRK06473 289 AIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILA 324
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 47-193 7.90e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 41.06  E-value: 7.90e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  47 SHPRAIEASTKYFLTQATASALMIFS--------GTLNYITTGNCQ--IMEMTNQTLMIIMILAMFIKVGLVPFHFWVPE 116
Cdd:MTH00226 176 SREEKMQAAYYFFFYTLIGSVLMLLClfslynihGTTDYLTLASCShvVSEQTQKWIFLGIFLAMAVKIPIFPFHIWLPK 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 117 TiQGMSPTASIFLLT--WQKLGPLILLFLMSPLVNF------EVISVVSILSVTVAGWLGLNQTQIRKLVALSSIAQMAW 188
Cdd:MTH00226 256 A-HVEAPVAGSVLLAgiLLKLGGYGLVRLSWPILPLgaqnlaPAVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGL 334


                 ....*
gi 187250396 189 TVIII 193
Cdd:MTH00226 335 VSITL 339
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-336 8.45e-04

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 36.85  E-value: 8.45e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 187250396  290 FFYLRLWYNSASTLPPNATNTKRLWRKSTQQTNLTINSMATAAMTLI 336
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLL 47
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 52-186 1.23e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 40.43  E-value: 1.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  52 IEASTKYFLTQATASALMIFS--------GTLNYITTGNCQIMEMTNQTLMIIMILAMFIKVGLVPFHFWVPET-----I 118
Cdd:MTH00204 162 VRASYYFFFYTFAGSVFMLLGifqlysitGTTDYQILLNIKLPLSIQKWLLVGFFLSLAVKIPQIPFHIWLPQAhveapV 241

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 187250396 119 QGMSPTASIFLltwqKLGPLILLFLMSPLVN------FEVISVVSILSVTVAGWLGLNQTQIRKLVALSSIAQM 186
Cdd:MTH00204 242 AGSVILAGILL----KLGGYGFLRFSWPLFPaaseyfAPLIVMLSVIAVIYGSLTTCRQVDFKRLIAYSSVAHM 311
ndhB CHL00049
NADH dehydrogenase subunit 2
 25-295 1.55e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 40.37  E-value: 1.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  25 LVLMWVSLELSTLVVLPLIA-NKSHPRAIEASTKYFLTQATASALMIFSGTLNY-ITTGNCQIMEMTNQTL-------MI 95
Cdd:CHL00049 133 LITIFVALECLSLCSYLLSGyTKKDVRSNEATMKYLLMGGASSSILVYGFSWLYgLSGGEIELQEIVNGLIntqmynsPG 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  96 IMILAMFIKVG------LVPFHFWVPETIQGmSPTASI-FLLTWQKLGPLILLFLMSPLVnFEVIS--------VVSILS 160
Cdd:CHL00049 213 ISIALIFITVGigfklsLAPFHQWTPDVYEG-SPTPVVaFLSVTSKVAASALATRIFDIP-FYFSSnewhllleILAILS 290

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTVIII-------KYAPSLTILAFYVYSI--TISTTLLTLEKLSTTSVSSLLL 231
Cdd:CHL00049 291 MILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIivgdsndGYASMITYMLFYIFMNlgTFACIVLFGLRTGTDNIRDYAG 370

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 187250396 232 SFSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:CHL00049 371 LYTKDPFLALSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
54-202 2.85e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 39.31  E-value: 2.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  54 ASTKYFLTQATASALMI--------FSGTLNY-ITTGNCQIMEMTNQTLMIIMILAMF-IKVGLVPFHFWVPETIQGMSP 123
Cdd:PRK07363 158 ASIKFLIYTAVSGLLVLaaflgivwLSGSTSFdYDAISTQNLSLNTQLILLTGLLLGFgIKIPLVPLHTWLPDAYTEASP 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396 124 TASIFL-LTWQKLGPLIL------LFLMSPLVNFEVISVVSILSVTVAGWLGLNQTQIRKLVALSSIAQMAWTVIIIKYA 196
Cdd:PRK07363 238 AVAILLgGVLAKLGTYGLlrfglqLFPQTWSLVAPGLAIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYILVAAAAG 317


                 ....*.
gi 187250396 197 PSLTIL 202
Cdd:PRK07363 318 TQLSLL 323
PRK12646 PRK12646
DUF4040 family protein;
77-193 3.55e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 39.35  E-value: 3.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  77 YITTGNCQIMEMTNQT-----------LMIIMILAMFIKVGLVPFHFWVPETIQGMSP-TASIFLLTWQKLGpLILLFLM 144
Cdd:PRK12646 185 YIMTGTNNITEILGQAdhiknhglfipMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPvSAYLHSATMVKAG-IFLLFRF 263

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 187250396 145 SPLVNFE-----VISVVSILSVTVAGWLGLNQTQIRKLVALSSIAQMAWTVIII 193
Cdd:PRK12646 264 TPLLGLSnmyiyIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMAMV 317
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 92-218 7.73e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 38.02  E-value: 7.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 187250396  92 TLMIIMILAMFIKVGLVPFHFWVPETIQGMSP-TASIFLLTWQKLGPLIL-----LFLMSPLVnFEVISVVSILSVTVAG 165
Cdd:MTH00032 226 IIGILLLIGCIGKSAQLGLHTWLPDAMEGPTPvSALIHAATMVTAGVFLMirsfpLFEKAPLT-LLIITIFGALTAFFAA 304

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 187250396 166 WLGLNQTQIRKLVALSSIAQMAWTVIIIKYAPSLTILAFYVYSITISTTLLTL 218
Cdd:MTH00032 305 TVGLVQNDLKKVIAYSTCSQLGYMVLIIGIEGSHNVGLFHLVNHAFFKALLFL 357
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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