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Conserved domains on  [gi|2026153858|ref|YP_010042640|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Aphidius gifuensis]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 1-85 1.23e-13

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 60.17  E-value: 1.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026153858  1 MMLNLKIFFFISSCFMYSYYYKHILLTLISLEFMMVNMIYNLYYMMMINEINLFMITIFLGISVCESVLGLSLLINLVRL 80
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*
gi 2026153858 81 SGNDY 85
Cdd:MTH00162  82 HGNDY 86
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 1-85 1.23e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 60.17  E-value: 1.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026153858  1 MMLNLKIFFFISSCFMYSYYYKHILLTLISLEFMMVNMIYNLYYMMMINEINLFMITIFLGISVCESVLGLSLLINLVRL 80
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*
gi 2026153858 81 SGNDY 85
Cdd:MTH00162  82 HGNDY 86
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
22-94 3.01e-03

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 33.69  E-value: 3.01e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2026153858 22 KHILLTLISLEFMM--VNMIYNLYYMMMINEINLFMITIFLGISVCESVLGLSLLINLVRLSGNDYNNNMKLLKC 94
Cdd:pfam00420 21 RNLLRVLLSLELMLnaVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 1-85 1.23e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 60.17  E-value: 1.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026153858  1 MMLNLKIFFFISSCFMYSYYYKHILLTLISLEFMMVNMIYNLYYMMMINEINLFMITIFLGISVCESVLGLSLLINLVRL 80
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*
gi 2026153858 81 SGNDY 85
Cdd:MTH00162  82 HGNDY 86
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 1-94 1.02e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 47.92  E-value: 1.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026153858  1 MMLNLKIFFFISSCFMYSYYYKHILLTLISLEFMMVNMIYNLYYMMMINEINLFMITIFLGISVCESVLGLSLLINLVRL 80
Cdd:MTH00149   4 MLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRL 83

                         90
                 ....*....|....
gi 2026153858 81 SGNDYNNNMKLLKC 94
Cdd:MTH00149  84 HGNDYVSSLSSLKF 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 2-94 1.33e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 42.65  E-value: 1.33e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026153858  2 MLNLKIFFFISSCFMYSYYYKHILLTLISLEFMMVNMIYNLYYMMMINEINLFMITIFLGISVCESVLGLSLLINLVRLS 81
Cdd:MTH00188   5 MILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSH 84

                         90
                 ....*....|...
gi 2026153858 82 GNDYNNNMKLLKC 94
Cdd:MTH00188  85 GSDYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 10-94 3.44e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 41.37  E-value: 3.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026153858 10 FISSCFMYSYYYKHILLTLISLEFMMVNMiynlYYMMMINEINLFMIT------IFLGISVCESVLGLSLLINLVRLSGN 83
Cdd:MTH00125  12 FMLSLLGLSFHRTHLMSALLCLESMMLSL----FIMLSLWPITTQTPSftpmpiILLTFSACEAGTGLALLVATTRTHGS 87

                         90
                 ....*....|.
gi 2026153858 84 DYNNNMKLLKC 94
Cdd:MTH00125  88 DHLKNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 7-94 4.89e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 38.41  E-value: 4.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026153858  7 IFFFISSCFMYS-----YYYKHILLTLISLEFMMVNMIYNLYYMMMINEINLFMIT--IFLGISVCESVLGLSLLINLVR 79
Cdd:MTH00126   4 VHFSFSSAFILGlmglaFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAApmLLLAFSACEASAGLALLVATAR 83

                         90
                 ....*....|....*
gi 2026153858 80 LSGNDYNNNMKLLKC 94
Cdd:MTH00126  84 THGTDRLQNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 7-92 2.62e-04

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 36.46  E-value: 2.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026153858  7 IFFFISSCFMYSYYYKHILLTLISLEFMMVNMIYNL--YYMMMINEINLFMITIFLGISVCESVLGLSLLINLVRLSGND 84
Cdd:MTH00181   6 ISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLalFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRTHGSD 85


                 ....*...
gi 2026153858 85 YNNNMKLL 92
Cdd:MTH00181  86 HLLKFNLL 93
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 3-94 7.29e-04

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 35.50  E-value: 7.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026153858  3 LNLKIFFFISSCFMYSYYYKHILLTLISLEFMMVNM-IYNLYYMMMINEINLFMITIFLGISVCESVLGLSLLINLVRLS 81
Cdd:MTH00013   5 LFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLaLFIPLSLMFANQVNGMLAIVLLTFGACEASLGLSLLVLMTRSY 84

                         90
                 ....*....|...
gi 2026153858 82 GNDYNNNMKLLKC 94
Cdd:MTH00013  85 GNDMLKSLTSNKC 97
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
22-94 3.01e-03

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 33.69  E-value: 3.01e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2026153858 22 KHILLTLISLEFMM--VNMIYNLYYMMMINEINLFMITIFLGISVCESVLGLSLLINLVRLSGNDYNNNMKLLKC 94
Cdd:pfam00420 21 RNLLRVLLSLELMLnaVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 23-94 6.51e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 33.04  E-value: 6.51e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2026153858 23 HILLTLISLEFMMVNMIYNLYYMMMINEINLFMIT--IFLGISVCESVLGLSLLINLVRLSGNDYNNNMKLLKC 94
Cdd:MTH00067  25 HLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLpmFMLTFSACEASTGLALMVATTRTHGTDHLKNLNLLQC 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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