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Conserved domains on  [gi|91176271|ref|YP_537140|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Balaenoptera omurai]

Protein Classification

NADH-ubiquinone oxidoreductase chain 4L( domain architecture ID 10009568)

NADH-ubiquinone oxidoreductase chain 4L is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) and is believed to belong to the minimal assembly required for catalysis; Complex I functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.59e-40

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177169  Cd Length: 98  Bit Score: 128.51  E-value: 2.59e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   1 MTLIHMNILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 91176271  81 VSNTYGTDYVQSLNLLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.59e-40

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 128.51  E-value: 2.59e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   1 MTLIHMNILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 91176271  81 VSNTYGTDYVQSLNLLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 3.12e-12

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 57.19  E-value: 3.12e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271    3 LIHMNILMAFSMSLVGLLmYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVMVS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLL-LRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 91176271   83 NTYGTDYVQSLNLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 12-96 2.14e-03

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440477  Cd Length: 99  Bit Score: 34.27  E-value: 2.14e-03
                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271 12 FSMSLVGLLMyRSHLMSALLCLEGMMLSLFIlaALTILNSHFTLAN--MMPIILLVFAACEAAIGLALLVMVSNTYGTDY 89
Cdd:COG0713 14 FAIGLYGVLT-RRNLIVVLMSIELMLNAVNL--NLVAFSRYLGDLDgqVFALFVIAVAAAEVAVGLAIIVALYRNRGTID 90


               ....*..
gi 91176271 90 VQSLNLL 96
Cdd:COG0713 91 VDDLNEL 97
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.59e-40

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 128.51  E-value: 2.59e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   1 MTLIHMNILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 91176271  81 VSNTYGTDYVQSLNLLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 1-98 3.94e-26

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 92.72  E-value: 3.94e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   1 MTLIHMNILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00126  1 MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVA 80

                        90
                ....*....|....*...
gi 91176271  81 VSNTYGTDYVQSLNLLQC 98
Cdd:MTH00126 81 TARTHGTDRLQNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 8.12e-24

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 86.82  E-value: 8.12e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   1 MTLIHMNILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00125  1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMPIILLTFSACEAGTGLALLVA 80

                        90
                ....*....|....*...
gi 91176271  81 VSNTYGTDYVQSLNLLQC 98
Cdd:MTH00125 81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.70e-19

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 75.03  E-value: 2.70e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   1 MTLIHMNILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00067  1 MSPTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLPMFMLTFSACEASTGLALMVA 80

                        90
                ....*....|....*...
gi 91176271  81 VSNTYGTDYVQSLNLLQC 98
Cdd:MTH00067 81 TTRTHGTDHLKNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 4-96 2.57e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 59.96  E-value: 2.57e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   4 IHMNILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVMVSN 83
Cdd:MTH00181  1 MMFVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNR 80

                        90
                ....*....|...
gi 91176271  84 TYGTDYVQSLNLL 96
Cdd:MTH00181 81 THGSDHLLKFNLL 93
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 3.12e-12

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 57.19  E-value: 3.12e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271    3 LIHMNILMAFSMSLVGLLmYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVMVS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLL-LRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 91176271   83 NTYGTDYVQSLNLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-97 1.08e-10

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 53.38  E-value: 1.08e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   1 MTLIHMNILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00043  1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                        90
                ....*....|....*..
gi 91176271  81 VSNTYGTDYVQSLNLLQ 97
Cdd:MTH00043 81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 8-98 6.72e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 48.43  E-value: 6.72e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   8 ILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLanMMPIILLVFAACEAAIGLALLVMVSNTYGT 87
Cdd:MTH00188  9 ILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKEL--YLSLVLLTFAACEASVGLALLVSLIRSHGS 86

                        90
                ....*....|.
gi 91176271  88 DYVQSLNLLQC 98
Cdd:MTH00188 87 DYVSSLNLIKC 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 9-98 9.93e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 48.30  E-value: 9.93e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   9 LMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILaaLTILNSHFTLANMMPIILLVFAACEAAIGLALLVMVSNTYGTD 88
Cdd:MTH00149 10 LFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVM--MFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGND 87

                        90
                ....*....|
gi 91176271  89 YVQSLNLLQC 98
Cdd:MTH00149 88 YVSSLSSLKF 97
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 6-92 8.27e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 45.53  E-value: 8.27e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   6 MNILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILaaLTILNSHFTLANMMPIILLVFAACEAAIGLALLVMVSNTY 85
Cdd:MTH00162  5 LIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFL--LFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRSH 82


                ....*..
gi 91176271  86 GTDYVQS 92
Cdd:MTH00162 83 GNDYFSS 89
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 1-98 4.14e-06

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 41.28  E-value: 4.14e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271   1 MTLIHMNILMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHfTLANMMPIILLVFAACEAAIGLALLVM 80
Cdd:MTH00013  1 MMSPLFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFAN-QVNGMLAIVLLTFGACEASLGLSLLVL 79

                        90
                ....*....|....*...
gi 91176271  81 VSNTYGTDYVQSLNLLQC 98
Cdd:MTH00013 80 MTRSYGNDMLKSLTSNKC 97
PRK05715 PRK05715
NADH-quinone oxidoreductase subunit NuoK;
1-96 8.76e-04

NADH-quinone oxidoreductase subunit NuoK;


Pssm-ID: 180218  Cd Length: 100  Bit Score: 35.15  E-value: 8.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271    1 MTLIHMNILMA--FSMSLVGLLMYRSHLMsALLCLEGMMLSLfILAALTILNSHFTLA-NMMPIILLVFAACEAAIGLAL 77
Cdd:PRK05715   2 IPLQHYLILAAilFCIGLVGLLLRRNAIV-VLMSIELMLNAV-NLNFVAFSSYLGDLDgQVFAFFVITVAAAEAAIGLAI 79

                         90
                 ....*....|....*....
gi 91176271   78 LVMVSNTYGTDYVQSLNLL 96
Cdd:PRK05715  80 LLQLYRNRGTIDVDDLNEL 98
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 12-97 1.94e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 34.62  E-value: 1.94e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271  12 FSMSLVGLLMYRSHLMSALLCLEGMMLSLFILAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVMVSNTYGTDYVQ 91
Cdd:MTH00180 13 FILGVLGIVLNRSNLIIMLMSIELMLLAISLLFLINSVAIDNLIGQIFTIMILTVAAAESAIGLAILVAYYRIRGTIAVK 92


                ....*.
gi 91176271  92 SLNLLQ 97
Cdd:MTH00180 93 SLNLLR 98
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 12-96 2.14e-03

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440477  Cd Length: 99  Bit Score: 34.27  E-value: 2.14e-03
                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 91176271 12 FSMSLVGLLMyRSHLMSALLCLEGMMLSLFIlaALTILNSHFTLAN--MMPIILLVFAACEAAIGLALLVMVSNTYGTDY 89
Cdd:COG0713 14 FAIGLYGVLT-RRNLIVVLMSIELMLNAVNL--NLVAFSRYLGDLDgqVFALFVIAVAAAEVAVGLAIIVALYRNRGTID 90


               ....*..
gi 91176271 90 VQSLNLL 96
Cdd:COG0713 91 VDDLNEL 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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