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Conserved domains on  [gi|113170437|ref|YP_717229|]
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RNA polymerase beta subunit (chloroplast) [Ostreococcus tauri]

Protein Classification

DNA-directed RNA polymerase subunit beta( domain architecture ID 1000963)

DNA-directed RNA polymerase subunit beta catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

CATH:  3.90.1110.10
EC:  2.7.7.6
Gene Ontology:  GO:0000428|GO:0003899|GO:0006351
PubMed:  6266829
SCOP:  4003708

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Ricin_B_lectin super family cl47023
Ricin-type beta-trefoil lectin domain;
3-1086 0e+00

Ricin-type beta-trefoil lectin domain;


The actual alignment was detected with superfamily member CHL00001:

Pssm-ID: 481363 [Multi-domain]  Cd Length: 1070  Bit Score: 1654.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    3 LFRQN----SALPNFLDSQRDSFRYFLETGIREELDFFSPIVGqslgssskrpTDRFISVSFHSKDFYFKKPHYTPQEAV 78
Cdd:CHL00001    1 MLRDGnegmSTIPGFNQIQFEGFCRFIDQGLTEELSKFPKIED----------TDQEIEFQLFVETYQLVEPLIKERDAV 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   79 QKLGTYKSSLIVPVHVYSKYLNLNATFPVAFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQFDKQGNRTHLVSF 158
Cdd:CHL00001   71 YESLTYSSELYVPAGLIWKKSRDMQEQTVFIGNIPLMNSLGTFIINGIYRVVINQILRSPGIYYRSELDHNGISVYTGTI 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  159 LSAYGSWLRFETDKKGVVFAHIDNLRKVPVTVFLQALGFSMDTIVGALKYPEALDPTL-KEVDWKLTTDEAILLLMSRLF 237
Cdd:CHL00001  151 ISDWGGRLELEIDRKARIWARVSRKQKISILVLLSAMGLNLREILDNVCYPEIFLSFLnDKEKKKIGSKENAILEFYQQF 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  238 PNR---PATVLRGRKFLFNQFFNPRrYSLSDVGRKRVNQKFRMRSKTKHLTLTPQDALAALDYLLRCENGETEfLDDIDH 314
Cdd:CHL00001  231 ACVggdPVFSESLCKELQKKFFQQR-CELGRIGRRNMNRKLNLDIPENNTFLLPQDVLAAADYLIGMKFGMGT-LDDIDH 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  315 LKNRRARLAGELIQTQFRLGLNRLERVIYNRISDenILRKTPgaLGSLNSLIRTQVLASVFQEFFGSNQLSQFMDQTNPL 394
Cdd:CHL00001  309 LKNKRIRSVADLLQDQFGLALNRLENAVRGTICG--AIRRKL--IPTPQNLVTSTPLTTTYESFFGSHPLSQFLDQTNPL 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  395 AEITHKRRLSSLGPGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYKlISESNtP 474
Cdd:CHL00001  385 TEIVHGRKLSSLGPGGLTGRTASFRVRDIHPSHYGRICPIDTSEGINAGLIGSLAIHARIGHWGSLESPFYE-ISERS-K 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  475 DRNGFFLLSAFYEEDTVVAQGDVDLSN-----FRIPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPFLEHDDANRA 549
Cdd:CHL00001  463 EERMVYLSPSEDEYYMIAAGNSLALNQgiqeeQVVPARYRQEFLTIAWEQIHLRSIFPFQYFSIGASLIPFLEHNDANRA 542
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  550 LMGSNMQRQAVSLLRSERPFVGTGLEAHVTRDIGATIVAKQNSYISYVDAQRIDYFTpvigdtnlidyqnltaedvfasn 629
Cdd:CHL00001  543 LMGSNMQRQAVPLSRSEKCIVGTGLERQVALDSGVVAIAEHEGKIIYTDTDKIILSG----------------------- 599
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  630 QFKHNTIWLTSYQRSNQDTCLNHKPLVEANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFEDAVLVSERLVY 709
Cdd:CHL00001  600 NGDTLSIPLVMYQRSNKNTCMHQKPQVRRGKCVKKGQILADGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVY 679
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  710 DDVFTSIHISRYEVSTARLREGQEYFTNQVDRN-----QYLDEFGVVKIGTWVEAGDVLVGKISPQ--PDSDNDPESRLL 782
Cdd:CHL00001  680 EDIYTSFHIRKYEIQTHVTSQGPERITKEIPHLeahllRNLDKNGIVMLGSWVETGDILVGKLTPQeaEESSYAPEGRLL 759
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  783 RAIFGGVARNTKTTSYCLSSGVSGRILDVRCEFKrqtkniEDESIESTGSVYVYLVEKRRLQVGDKVAGRHGNKGIVSNI 862
Cdd:CHL00001  760 RAIFGIQVSTSKETCLKLPIGGRGRVIDVRWIQK------KGGSSYNPETIHVYILQKREIQVGDKVAGRHGNKGIISKI 833
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  863 LPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTLKQNFKVLPFDEMHGAEVSRGFVYHYLYKSRLLTQQ 942
Cdd:CHL00001  834 LPRQDMPYLQDGTPVDMVLNPLGVPSRMNVGQIFECLLGLAGDLLNRHYRIAPFDERYEQEASRKLVFSELYEASKQTAN 913
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  943 KWLFKPNSPGKSIVFDGRTGLNFDQPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWAL 1022
Cdd:CHL00001  914 PWVFEPEYPGKSRLFDGRTGDPFEQPVTIGKAYILKLIHQVDDKIHARSSGPYALVTQQPLRGRSKQGGQRVGEMEVWAL 993
                        1050      1060      1070      1080      1090      1100
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 113170437 1023 EGFGAAYVLQELLTIKSDDMIGRNRAFMSMIRGTLLPK-SGIPESFKVLVSELRGLCLDMSIARI 1086
Cdd:CHL00001  994 EGFGVAYILQEMLTYKSDHIRARQEVLGAIITGGTIPKpEDAPESFRLLVRELRSLALELNHFLV 1058
 
Name Accession Description Interval E-value
rpoB CHL00001
RNA polymerase beta subunit
3-1086 0e+00

RNA polymerase beta subunit


Pssm-ID: 214330 [Multi-domain]  Cd Length: 1070  Bit Score: 1654.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    3 LFRQN----SALPNFLDSQRDSFRYFLETGIREELDFFSPIVGqslgssskrpTDRFISVSFHSKDFYFKKPHYTPQEAV 78
Cdd:CHL00001    1 MLRDGnegmSTIPGFNQIQFEGFCRFIDQGLTEELSKFPKIED----------TDQEIEFQLFVETYQLVEPLIKERDAV 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   79 QKLGTYKSSLIVPVHVYSKYLNLNATFPVAFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQFDKQGNRTHLVSF 158
Cdd:CHL00001   71 YESLTYSSELYVPAGLIWKKSRDMQEQTVFIGNIPLMNSLGTFIINGIYRVVINQILRSPGIYYRSELDHNGISVYTGTI 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  159 LSAYGSWLRFETDKKGVVFAHIDNLRKVPVTVFLQALGFSMDTIVGALKYPEALDPTL-KEVDWKLTTDEAILLLMSRLF 237
Cdd:CHL00001  151 ISDWGGRLELEIDRKARIWARVSRKQKISILVLLSAMGLNLREILDNVCYPEIFLSFLnDKEKKKIGSKENAILEFYQQF 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  238 PNR---PATVLRGRKFLFNQFFNPRrYSLSDVGRKRVNQKFRMRSKTKHLTLTPQDALAALDYLLRCENGETEfLDDIDH 314
Cdd:CHL00001  231 ACVggdPVFSESLCKELQKKFFQQR-CELGRIGRRNMNRKLNLDIPENNTFLLPQDVLAAADYLIGMKFGMGT-LDDIDH 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  315 LKNRRARLAGELIQTQFRLGLNRLERVIYNRISDenILRKTPgaLGSLNSLIRTQVLASVFQEFFGSNQLSQFMDQTNPL 394
Cdd:CHL00001  309 LKNKRIRSVADLLQDQFGLALNRLENAVRGTICG--AIRRKL--IPTPQNLVTSTPLTTTYESFFGSHPLSQFLDQTNPL 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  395 AEITHKRRLSSLGPGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYKlISESNtP 474
Cdd:CHL00001  385 TEIVHGRKLSSLGPGGLTGRTASFRVRDIHPSHYGRICPIDTSEGINAGLIGSLAIHARIGHWGSLESPFYE-ISERS-K 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  475 DRNGFFLLSAFYEEDTVVAQGDVDLSN-----FRIPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPFLEHDDANRA 549
Cdd:CHL00001  463 EERMVYLSPSEDEYYMIAAGNSLALNQgiqeeQVVPARYRQEFLTIAWEQIHLRSIFPFQYFSIGASLIPFLEHNDANRA 542
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  550 LMGSNMQRQAVSLLRSERPFVGTGLEAHVTRDIGATIVAKQNSYISYVDAQRIDYFTpvigdtnlidyqnltaedvfasn 629
Cdd:CHL00001  543 LMGSNMQRQAVPLSRSEKCIVGTGLERQVALDSGVVAIAEHEGKIIYTDTDKIILSG----------------------- 599
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  630 QFKHNTIWLTSYQRSNQDTCLNHKPLVEANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFEDAVLVSERLVY 709
Cdd:CHL00001  600 NGDTLSIPLVMYQRSNKNTCMHQKPQVRRGKCVKKGQILADGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVY 679
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  710 DDVFTSIHISRYEVSTARLREGQEYFTNQVDRN-----QYLDEFGVVKIGTWVEAGDVLVGKISPQ--PDSDNDPESRLL 782
Cdd:CHL00001  680 EDIYTSFHIRKYEIQTHVTSQGPERITKEIPHLeahllRNLDKNGIVMLGSWVETGDILVGKLTPQeaEESSYAPEGRLL 759
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  783 RAIFGGVARNTKTTSYCLSSGVSGRILDVRCEFKrqtkniEDESIESTGSVYVYLVEKRRLQVGDKVAGRHGNKGIVSNI 862
Cdd:CHL00001  760 RAIFGIQVSTSKETCLKLPIGGRGRVIDVRWIQK------KGGSSYNPETIHVYILQKREIQVGDKVAGRHGNKGIISKI 833
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  863 LPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTLKQNFKVLPFDEMHGAEVSRGFVYHYLYKSRLLTQQ 942
Cdd:CHL00001  834 LPRQDMPYLQDGTPVDMVLNPLGVPSRMNVGQIFECLLGLAGDLLNRHYRIAPFDERYEQEASRKLVFSELYEASKQTAN 913
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  943 KWLFKPNSPGKSIVFDGRTGLNFDQPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWAL 1022
Cdd:CHL00001  914 PWVFEPEYPGKSRLFDGRTGDPFEQPVTIGKAYILKLIHQVDDKIHARSSGPYALVTQQPLRGRSKQGGQRVGEMEVWAL 993
                        1050      1060      1070      1080      1090      1100
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 113170437 1023 EGFGAAYVLQELLTIKSDDMIGRNRAFMSMIRGTLLPK-SGIPESFKVLVSELRGLCLDMSIARI 1086
Cdd:CHL00001  994 EGFGVAYILQEMLTYKSDHIRARQEVLGAIITGGTIPKpEDAPESFRLLVRELRSLALELNHFLV 1058
rpoB TIGR02013
DNA-directed RNA polymerase, beta subunit; This model describes orthologs of the beta subunit ...
10-1083 0e+00

DNA-directed RNA polymerase, beta subunit; This model describes orthologs of the beta subunit of Bacterial RNA polymerase. The core enzyme consists of two alpha chains, one beta chain, and one beta' subunit. [Transcription, DNA-dependent RNA polymerase]


Pssm-ID: 273928 [Multi-domain]  Cd Length: 1065  Bit Score: 1240.70  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    10 LPNFLDSQRDSFRYFLET----------GIREELDFFSPIvgqslgssskrpTDRFISVSFHSKDFYFKKPHYTPQEAVQ 79
Cdd:TIGR02013   17 VPNLLEIQLDSYDWFLQQdtppekrkeeGLEEVFKSIFPI------------EDYTGNIELEYLSYRLGEPKYSVEECKE 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    80 KLGTYKSSLIVPVHVYSKYLNLNATF---PVAFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQFD--KQGNRTH 154
Cdd:TIGR02013   85 RGLTYSAPLKVKLRLINKEEDGTKEIkeqDVYMGDIPLMTDRGTFIINGAERVVVSQLHRSPGVFFSSEKDttKSGKVLF 164
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   155 LVSFLSAYGSWLRFETDKKGVVFAHIDNLRKVPVTVFLQALGFSMDT-IVGALKYPEALDPTLkEVDWKLTTDEAILLLM 233
Cdd:TIGR02013  165 SARIIPYRGSWLEFETDKKDVLYVRIDRKRKLPATVLLRALGYTIDTlILNRLGSGEYIRNTL-RKDPTNSEEEALVEIY 243
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   234 SRLFPNRPATVLRGRKFLFNQFFNPRRYSLSDVGRKRVNQKFRMRSKTKHLTLTPQDALAALDYLLRCENGETEfLDDID 313
Cdd:TIGR02013  244 RKLRPGEPPTVEAARSLLENLFFDPKRYDLGRVGRYKLNKKLGLDVPESIGVLTKEDIIATIKYLIKLRNGKGE-IDDID 322
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   314 HLKNRRARLAGELIQTQFRLGLNRLERVIYNRISDENILRKTPGalgslnSLIRTQVLASVFQEFFGSNQLSQFMDQTNP 393
Cdd:TIGR02013  323 HLGNRRIRSVGELLQNQFRVGLARMERIVRERMSTQDTDTLTPQ------DLINAKPISAAIKEFFGSSQLSQFMDQTNP 396
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   394 LAEITHKRRLSSLGPGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYKLISESNT 473
Cdd:TIGR02013  397 LAELTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLSTYARVNEYGFIETPYRKVKDGKVV 476
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   474 PDRNGFFLlSAFYEEDTVVAQGDVDL---SNF---RIPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPFLEHDDAN 547
Cdd:TIGR02013  477 VTDEIDYL-TADEEDNYVIAQANAPLdenGRFvedLVVARYRGEITLVSPDQVDYMDVSPKQVVSVAASLIPFLEHDDAN 555
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   548 RALMGSNMQRQAVSLLRSERPFVGTGLEAHVTRDIGATIVAKQNSYISYVDAQRIdyftpVIGDTNLIDYQNlTAEDVFA 627
Cdd:TIGR02013  556 RALMGSNMQRQAVPLLRSEAPLVGTGMEAKVARDSGAVIVAKRGGVVEYVDAKRI-----VIRYDEDEEEPD-GGIDIYR 629
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   628 snqfkhntiwLTSYQRSNQDTCLNHKPLVEANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFEDAVLVSERL 707
Cdd:TIGR02013  630 ----------LLKYQRSNQDTCINQRPIVSVGDRVEAGDVLADGPSTDLGELALGRNVLVAFMPWNGYNYEDAILISERL 699
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   708 VYDDVFTSIHISRYEVSTARLREGQEYFTNQVD-------RNqyLDEFGVVKIGTWVEAGDVLVGKISPQPDSDNDPESR 780
Cdd:TIGR02013  700 VKDDVFTSIHIEEYEVEARDTKLGPEEITRDIPnvseealRN--LDENGIVRIGAEVKAGDILVGKVTPKGETELTPEEK 777
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   781 LLRAIFGGVARNTKTTSYCLSSGVSGRILDVRcEFKRQTKNIEDESIEStgSVYVYLVEKRRLQVGDKVAGRHGNKGIVS 860
Cdd:TIGR02013  778 LLRAIFGEKARDVRDTSLRVPPGVEGTVIDVK-VFSREQGDELPPGVNK--LVKVYIAQKRKIQVGDKMAGRHGNKGVVS 854
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   861 NILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTLkqnfkvlpfdEMHGAEVSRGFVYHYLYKSRLLT 940
Cdd:TIGR02013  855 KILPIEDMPFLEDGTPVDIVLNPLGVPSRMNIGQILETHLGWAGKRL----------GRKGVPIATPVFDGASEEEIKEY 924
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   941 QQKWLFKPNspGKSIVFDGRTGLNFDQPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVW 1020
Cdd:TIGR02013  925 LEKAGLPRD--GKVRLYDGRTGEQFDRPVTVGYMYMLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVW 1002
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 113170437  1021 ALEGFGAAYVLQELLTIKSDDMIGRNRAFMSMIRGTLLPKSGIPESFKVLVSELRGLCLDMSI 1083
Cdd:TIGR02013 1003 ALEAYGAAYTLQEMLTVKSDDVVGRTKAYEAIVKGENVPEPGIPESFNVLIKELQSLGLDIEL 1065
RpoB COG0085
DNA-directed RNA polymerase, beta subunit/140 kD subunit [Transcription]; DNA-directed RNA ...
10-1083 0e+00

DNA-directed RNA polymerase, beta subunit/140 kD subunit [Transcription]; DNA-directed RNA polymerase, beta subunit/140 kD subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 439855 [Multi-domain]  Cd Length: 1001  Bit Score: 1218.80  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   10 LPNFLDSQRDSFRYFLETGIREELDFFSPIvgqslgssskRPTDRFISVSFhsKDFYFKKPHYTPQEAVQKLGTYKSSLI 89
Cdd:COG0085    13 LPNLLEIQLDSFNWFLEEGLQEIFDEISPI----------EDFTGNLSLEF--GDYRLGEPKYTPEECKERDLTYAAPLY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   90 VPVHVYSKYLNLNATFPVAFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQFDKQGNRTHLVSFLSAYGSWLRFE 169
Cdd:COG0085    81 VKVRLVNKETGEIKEQEVFMGDFPLMTDSGTFIINGTERVIVSQLVRSPGVYFVEEEDKSGKDLYSAKVIPSRGAWLEFE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  170 TDKKGVVFAHIDNLRKVPVTVFLQALGFSMD----TIVGALKYPEALDPTLKEvDWKLTTDEAILLLMSRLFPNRPATVL 245
Cdd:COG0085   161 TDKDGTIYVRIDRKRKIPVTVLLRALGLETDeeilEAFGDDPIQEYILATLEK-DNTKTQEEALLEIYRKLRPGEPPTIE 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  246 RGRKFLFNQFFNPRRYSLSDVGRKRVNQKFRMRSKTKHLTLTPQDALAALDYLLRCENGEtEFLDDIDHLKNRRARLAGE 325
Cdd:COG0085   240 RAEQLLDNLFFDPKRYDLAHVGRYKINKKLGLDVPPEDRVLTAEDIVATIKYLLELHLGE-REPDDIDHLGNRRVRLVGE 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  326 LIQTQFRLGLNRLERVIYNRISDENILRKTPgalgslNSLIRTQVLASVFQEFFGSNQLSQFMDQTNPLAEITHKRRLSS 405
Cdd:COG0085   319 LLQNQFRVGLSRMERVVRERMTTQDVEAITP------QSLINIRPVVAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  406 LGPGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYKLIsesntpdrNGFF----- 480
Cdd:COG0085   393 LGPGGLSRERAGFEVRDVHPSHYGRMCPIETPEGPNIGLIGSLALYARVNEYGFIETPYRKVE--------NGKVtdeie 464
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  481 LLSAFYEEDTVVAQGDVDLSNF------RIPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPFLEHDDANRALMGSN 554
Cdd:COG0085   465 YLTADEEENYYIAQANAPLDEDgnfleeRVLVRYRGEEVLVPPEEVDYMDVSPKQIVSVATSLIPFLEHDDANRALMGAN 544
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  555 MQRQAVSLLRSERPFVgtgleahvtrdigativakqnsyisyvdaqridyftpvigdtnlidyqnltaedvfasnqfkhn 634
Cdd:COG0085   545 MQRQAVPLLRPEAPLL---------------------------------------------------------------- 560
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  635 TIWLTSYQRSNQDTCLNHKPLVEANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFEDAVLVSERLVYDDVFT 714
Cdd:COG0085   561 HYPLQKFQRSNQGTCINQRPIVRVGDRVEKGDVLADGPATDNGELALGQNLLVAFMPWEGYNYEDAIIISERLVKDDVLT 640
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  715 SIHISRYEVSTARLREGQEYFTN-------QVDRNqyLDEFGVVKIGTWVEAGDVLVGKISPQPDSDNDPESRLLRAIFG 787
Cdd:COG0085   641 SIHIEEYEIEARDTKLGPEEITRdipnvseEALRN--LDEDGIIRIGAEVKGGDILVGKVTPKGETELTPEERLLRAIFG 718
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  788 GVARNTKTTSYCLSSGVSGRILDVRcEFKRqtkniEDESIESTGS---VYVYLVEKRRLQVGDKVAGRHGNKGIVSNILP 864
Cdd:COG0085   719 EKAREVRDTSLRVPHGEKGKVIDVK-VFSR-----EEGDELPPGVnklVRVYVAQKRKIEVGDKLAGRHGNKGVISRILP 792
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  865 RVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTLKQNFKVLPFDEMHGAEVSRgfvyhYLYKSRLltqqkw 944
Cdd:COG0085   793 QEDMPFLEDGTPVDIVLNPLGVPSRMNVGQVLETHLGWAAALLGRRVATPVFDGAPEEEIRE-----LLEKAGL------ 861
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  945 lfkpNSPGKSIVFDGRTGLNFDQPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWALEG 1024
Cdd:COG0085   862 ----PPDGKEVLYDGRTGEPFDNPVTVGYMYYLKLHHMVDDKIHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEA 937
                        1050      1060      1070      1080      1090
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 113170437 1025 FGAAYVLQELLTIKSDDMIGRNRAFMSMIRGTLLPKSGIPESFKVLVSELRGLCLDMSI 1083
Cdd:COG0085   938 YGAAYTLQERLTIKSDDVCGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLGLDVEV 996
RNA_pol_B_RPB2 cd00653
RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. ...
13-1083 0e+00

RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase complex contains two related members of this family, in each case they are the two largest subunits.The clamp is a mobile structure that grips DNA during elongation.


Pssm-ID: 238353 [Multi-domain]  Cd Length: 866  Bit Score: 769.81  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   13 FLDSQRDSFRYFLETGIREELDFFSPIVgqslgssskrPTDRFISVSFHSKDFYFKKP---------HYTPQEAVQKLGT 83
Cdd:cd00653     1 LVKQQIDSFNYFLNVGLQEIVKSIPPIT----------DTDDDGRLKLKFGDIYLGKPkveeggvtrKLTPNECRLRDLT 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   84 YKSSLIVPVHVYSKYLNLNATFPVAFCDLPLMTEH------------------------GTFILNGSPRVIVHQIVRCPG 139
Cdd:cd00653    71 YSAPLYVDIRLTVNDKGKIKEQEVFIGEIPIMLRSklcnlngltpeeliklgecpldpgGYFIINGTEKVIINQEQRSPN 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  140 VYLKpqFDKQGNRTHLVSFLSAY----GSWLRFETD-KKGVVFAHIDNLRKvpvtvflqalgfsmdtivgalkypealdp 214
Cdd:cd00653   151 VIIV--EDSKGKRIYTKTSIPSYspyrGSWLEVKSDkKKDRIYVRIDLKRQ----------------------------- 199
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  215 tlkevdwklttDEAilllmsrlfpnrpatvlrgRKFLFNQFFnprryslsdvgrkrvnqkfrmrsktkhltltpqDALAA 294
Cdd:cd00653   200 -----------EEA-------------------LKYIGKRFE---------------------------------DLIYM 216
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  295 LDYLLRCENGETEfLDDIDHLKNRRARLAGELIQTQFRLGLNRLERVIYNRISDENILRKTPgalgSLNSLIRTQVLASV 374
Cdd:cd00653   217 IRKLILLVLGKGK-LDDIDHLGNKRVRLAGELLQNLFRSGLKRLEREVKEKLQKQLSKKKDL----TPQLLINSKPITSG 291
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  375 FQEFFGSNQ------------LSQFMDQTNPLAEITHKRRLSSlgpGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNA 442
Cdd:cd00653   292 IKEFLATGNwgskrflmqrsgLSQVLDRLNPLSELSHKRRISS---LGLFRERKGFEVRDLHPSHWGRICPIETPEGENC 368
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  443 GLVGSIATFTQINknGFLESPYYKLISESntpdrngffllsafyeedtvvaqgdvdlsnfriptrnksqftenTVQEInf 522
Cdd:cd00653   369 GLVKNLALMARIS--GRIERPYRIVEKEV--------------------------------------------THIEI-- 400
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  523 lglCPIQFMSIATSLIPFLEHDDANRALMGSNMQRQAV----------------SLLRSERPFVGTGLEAHVtrdigati 586
Cdd:cd00653   401 ---SPSQILSVAASLIPFPEHNQSPRNLYQSNMQKQAVgtpalnqqyrmdtklyLLLYPQKPLVGTGIEEYI-------- 469
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  587 vakqnsyisyvdaqridyftpvigdtnlidyqnltaedvfasnqfkhntiwltsyqrsnqdtclnhkplveantwveagd 666
Cdd:cd00653       --------------------------------------------------------------------------------
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  667 cladnaatAKGELALGRNILIGYMPWEGYNFEDAVLVSERLVYDDVFTSIHISRYEVSTARLREGQEYFTNQVDRN---- 742
Cdd:cd00653   470 --------AFGELPLGQNAIVAVMSYSGYNFEDAIIINKSSVDRGFFRSIHYKKYEIELRKTKNGPEEITRGDIPNvsee 541
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  743 --QYLDEFGVVKIGTWVEAGDVLVGKISPQPDSDNDPesrllraIFGGVARNTKTTSYCLSSGVSGRILDVRCeFKRQTK 820
Cdd:cd00653   542 klKNLDEDGIIRPGARVEPGDILVGKITPKGETESTP-------IFGEKARDVRDTSLKYPGGEKGIVDDVKI-FSRELN 613
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  821 NIEDESIEstgsvyVYLVEKRRLQVGDKVAGRHGNKGIVSNILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLL 900
Cdd:cd00653   614 DGGNKLVK------VYIRQKRKPQIGDKFASRHGQKGVISKILPQEDMPFTEDGIPPDIILNPHGFPSRMTIGQLLESLL 687
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  901 GLAANTLKQNFKVLPFDEMHGAEVSRGFVYHYLyksrlltqqkwlfkpNSPGKSIVFDGRTGLNFDQPVTVGYPYILKLV 980
Cdd:cd00653   688 GKAGALLGKFGDATPFDGAEEEDISELLGEAGL---------------NYYGKEVLYDGRTGEPLEAPIFVGPVYYQRLK 752
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  981 HLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWALEGFGAAYVLQELLTIKSDDMIGRNRAFMSMI------- 1053
Cdd:cd00653   753 HMVDDKIHARSTGPYSLLTRQPLKGRSRGGGQRFGEMERDALIAHGAAYLLQERLTIKSDDVVARVCVKCGIIlsanlcr 832
                        1130      1140      1150
                  ....*....|....*....|....*....|...
gi 113170437 1054 ---RGTLLPKSGIPESFKVLVSELRGLCLDMSI 1083
Cdd:cd00653   833 lckKGTNISKVGIPYAFKLLFQELQSMNIDPRL 865
RNA_pol_Rpb2_6 pfam00562
RNA polymerase Rpb2, domain 6; RNA polymerases catalyze the DNA dependent polymerization of ...
587-1008 7.08e-146

RNA polymerase Rpb2, domain 6; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). This domain represents the hybrid binding domain and the wall domain. The hybrid binding domain binds the nascent RNA strand / template DNA strand in the Pol II transcription elongation complex. This domain contains the important structural motifs, switch 3 and the flap loop and binds an active site metal ion. This domain is also involved in binding to Rpb1 and Rpb3. Many of the bacterial members contain large insertions within this domain, as region known as dispensable region 2 (DRII).


Pssm-ID: 459854 [Multi-domain]  Cd Length: 371  Bit Score: 441.20  E-value: 7.08e-146
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   587 VAKQNSYISYVDAQRIDYftpvigdtnlidyQNLTAEDvfasnqfKHNTIWLTSYQRSNQDT---CLNHKPLVEANTwVE 663
Cdd:pfam00562    1 VASLIPFVDHNQSPRNTY-------------QCAMGKQ-------AMGIYTLNKFYRSDQNTyvlCYPQKPLVKTGA-VE 59
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   664 AGDcladnaataKGELALGRNILIGYMPWEGYNFEDAVLVSERLVYDDVFTSIHISRYEVSTARLrEGQEYFTNQVDRN- 742
Cdd:pfam00562   60 AGG---------FGELPLGQNAIVAVMSYTGYNQEDAIIINKSSVDRGFFTSIHIKEIEARKTKL-GPIEEITRDIPNVs 129
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   743 ----QYLDEFGVVKIGTWVEAGDVLVGKISPqpdsdnDPESRLLRAIFGGVARNTKTTSYCLSSGVSGRILDVRcefkrq 818
Cdd:pfam00562  130 eealKKLDEDGIVRVGAEVKPGDILVGKVGP------TELTKLLRAIFGEKARDVKDTSLKVPPGEEGVVDDVI------ 197
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   819 tknIEDESIESTGSVYVYLVEKRRLQVGDKVAGRHGNKGIVSNILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFEC 898
Cdd:pfam00562  198 ---VFELPPGGIKMVKVYIRQKRKPEVGDKFASRHGQKGVVSRILPQEDMPFTEDGIPPDIILNPHGVPSRMTIGQLLET 274
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   899 LLGLAANTLKQNFKVLPFDemhGAEVSRGFVYHYLYKSRLltqqkwlfkpNSPGKSIVFDGRTGLNFDQPVTVGYPYILK 978
Cdd:pfam00562  275 HLGKAAALLGVFVDATPFD---GASTEVEDIGELLEKAGY----------NYYGKEVLYDGRTGEPFEAPIFVGPIYYQK 341
                          410       420       430
                   ....*....|....*....|....*....|
gi 113170437   979 LVHLVDDKIHARSTGPYSLVTQQPLGGRSK 1008
Cdd:pfam00562  342 LKHMVDDKIHARSTGPYSLLTRQPLGGRAR 371
 
Name Accession Description Interval E-value
rpoB CHL00001
RNA polymerase beta subunit
3-1086 0e+00

RNA polymerase beta subunit


Pssm-ID: 214330 [Multi-domain]  Cd Length: 1070  Bit Score: 1654.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    3 LFRQN----SALPNFLDSQRDSFRYFLETGIREELDFFSPIVGqslgssskrpTDRFISVSFHSKDFYFKKPHYTPQEAV 78
Cdd:CHL00001    1 MLRDGnegmSTIPGFNQIQFEGFCRFIDQGLTEELSKFPKIED----------TDQEIEFQLFVETYQLVEPLIKERDAV 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   79 QKLGTYKSSLIVPVHVYSKYLNLNATFPVAFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQFDKQGNRTHLVSF 158
Cdd:CHL00001   71 YESLTYSSELYVPAGLIWKKSRDMQEQTVFIGNIPLMNSLGTFIINGIYRVVINQILRSPGIYYRSELDHNGISVYTGTI 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  159 LSAYGSWLRFETDKKGVVFAHIDNLRKVPVTVFLQALGFSMDTIVGALKYPEALDPTL-KEVDWKLTTDEAILLLMSRLF 237
Cdd:CHL00001  151 ISDWGGRLELEIDRKARIWARVSRKQKISILVLLSAMGLNLREILDNVCYPEIFLSFLnDKEKKKIGSKENAILEFYQQF 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  238 PNR---PATVLRGRKFLFNQFFNPRrYSLSDVGRKRVNQKFRMRSKTKHLTLTPQDALAALDYLLRCENGETEfLDDIDH 314
Cdd:CHL00001  231 ACVggdPVFSESLCKELQKKFFQQR-CELGRIGRRNMNRKLNLDIPENNTFLLPQDVLAAADYLIGMKFGMGT-LDDIDH 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  315 LKNRRARLAGELIQTQFRLGLNRLERVIYNRISDenILRKTPgaLGSLNSLIRTQVLASVFQEFFGSNQLSQFMDQTNPL 394
Cdd:CHL00001  309 LKNKRIRSVADLLQDQFGLALNRLENAVRGTICG--AIRRKL--IPTPQNLVTSTPLTTTYESFFGSHPLSQFLDQTNPL 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  395 AEITHKRRLSSLGPGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYKlISESNtP 474
Cdd:CHL00001  385 TEIVHGRKLSSLGPGGLTGRTASFRVRDIHPSHYGRICPIDTSEGINAGLIGSLAIHARIGHWGSLESPFYE-ISERS-K 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  475 DRNGFFLLSAFYEEDTVVAQGDVDLSN-----FRIPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPFLEHDDANRA 549
Cdd:CHL00001  463 EERMVYLSPSEDEYYMIAAGNSLALNQgiqeeQVVPARYRQEFLTIAWEQIHLRSIFPFQYFSIGASLIPFLEHNDANRA 542
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  550 LMGSNMQRQAVSLLRSERPFVGTGLEAHVTRDIGATIVAKQNSYISYVDAQRIDYFTpvigdtnlidyqnltaedvfasn 629
Cdd:CHL00001  543 LMGSNMQRQAVPLSRSEKCIVGTGLERQVALDSGVVAIAEHEGKIIYTDTDKIILSG----------------------- 599
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  630 QFKHNTIWLTSYQRSNQDTCLNHKPLVEANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFEDAVLVSERLVY 709
Cdd:CHL00001  600 NGDTLSIPLVMYQRSNKNTCMHQKPQVRRGKCVKKGQILADGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVY 679
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  710 DDVFTSIHISRYEVSTARLREGQEYFTNQVDRN-----QYLDEFGVVKIGTWVEAGDVLVGKISPQ--PDSDNDPESRLL 782
Cdd:CHL00001  680 EDIYTSFHIRKYEIQTHVTSQGPERITKEIPHLeahllRNLDKNGIVMLGSWVETGDILVGKLTPQeaEESSYAPEGRLL 759
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  783 RAIFGGVARNTKTTSYCLSSGVSGRILDVRCEFKrqtkniEDESIESTGSVYVYLVEKRRLQVGDKVAGRHGNKGIVSNI 862
Cdd:CHL00001  760 RAIFGIQVSTSKETCLKLPIGGRGRVIDVRWIQK------KGGSSYNPETIHVYILQKREIQVGDKVAGRHGNKGIISKI 833
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  863 LPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTLKQNFKVLPFDEMHGAEVSRGFVYHYLYKSRLLTQQ 942
Cdd:CHL00001  834 LPRQDMPYLQDGTPVDMVLNPLGVPSRMNVGQIFECLLGLAGDLLNRHYRIAPFDERYEQEASRKLVFSELYEASKQTAN 913
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  943 KWLFKPNSPGKSIVFDGRTGLNFDQPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWAL 1022
Cdd:CHL00001  914 PWVFEPEYPGKSRLFDGRTGDPFEQPVTIGKAYILKLIHQVDDKIHARSSGPYALVTQQPLRGRSKQGGQRVGEMEVWAL 993
                        1050      1060      1070      1080      1090      1100
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 113170437 1023 EGFGAAYVLQELLTIKSDDMIGRNRAFMSMIRGTLLPK-SGIPESFKVLVSELRGLCLDMSIARI 1086
Cdd:CHL00001  994 EGFGVAYILQEMLTYKSDHIRARQEVLGAIITGGTIPKpEDAPESFRLLVRELRSLALELNHFLV 1058
rpoB PRK00405
DNA-directed RNA polymerase subunit beta; Reviewed
10-1083 0e+00

DNA-directed RNA polymerase subunit beta; Reviewed


Pssm-ID: 234749 [Multi-domain]  Cd Length: 1112  Bit Score: 1324.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   10 LPNFLDSQRDSFRYFL-------ETGIREELDFFSPIVgqslgSSSKRptdrfISVSFhsKDFYFKKPHYTPQEAVQKLG 82
Cdd:PRK00405   24 LPNLLEIQLDSFDWFLqldvppeDEGLEEVFRSIFPIE-----DFNGN-----LSLEF--VSYELGEPKYDVEECKERGL 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   83 TYKSSLIVPVHVYSKylnlnATF-----PVAFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQFDKQ--GNRTHL 155
Cdd:PRK00405   92 TYSAPLRVKLRLINK-----ETGeikeqEVYMGDIPLMTENGTFIINGTERVIVSQLHRSPGVYFDHDKDKTssGKLLYS 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  156 VSFLSAYGSWLRFETDKKGVVFAHIDNLRKVPVTVFLQALGFS---------------------MDTIVGALKYPEALDP 214
Cdd:PRK00405  167 ARIIPYRGSWLEFEFDPKDILYVRIDRRRKLPVTVLLRALGYSdeeildlfyekeefgkeievpVEYLLGKVLAEDIVDE 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  215 TLKEV-----------------------DWKLTTDEAILLLMSRLFPNRPATVLRGRKFLFNQFFNPRRYSLSDVGRKRV 271
Cdd:PRK00405  247 ETGEVlaeandeiteeldgpyirntlekDPTSSREEALVEIYRRLRPGEPPTVEAARSLLENLFFDPKRYDLSKVGRYKL 326
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  272 NQKFRMRSKTKHLTLTPQDALAALDYLLRCENGETEfLDDIDHLKNRRARLAGELIQTQFRLGLNRLERVIYNRIS---D 348
Cdd:PRK00405  327 NKKLGLDEDEDVRVLTKEDIIATIKYLINLRNGKGE-VDDIDHLGNRRVRSVGELLQNQFRIGLSRMERAVRERMSlqdL 405
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  349 ENIlrkTPgalgslNSLIRTQVLASVFQEFFGSNQLSQFMDQTNPLAEITHKRRLSSLGPGGLNRDRAGLIVRGIHPSYY 428
Cdd:PRK00405  406 DTL---TP------QDLINAKPVVAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLTRERAGFEVRDVHPTHY 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  429 GRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYKLIsesntpdrNGFFL-----LSAFYEEDTVVAQGDVDLS--- 500
Cdd:PRK00405  477 GRICPIETPEGPNIGLINSLATYARVNEYGFIETPYRKVV--------DGKVTdeivyLTADEEDNYVIAQANAPLDedg 548
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  501 NF---RIPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPFLEHDDANRALMGSNMQRQAVSLLRSERPFVGTGLEAH 577
Cdd:PRK00405  549 RFvdeLVTARYKGEFVLVPPEEVDYMDVSPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPLLRPEAPLVGTGMERR 628
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  578 VTRDIGATIVAKQNSYISYVDAQRIdyftpvigdtnLIDYQNLTAEDvfasnqfKHNTIW-LTSYQRSNQDTCLNHKPLV 656
Cdd:PRK00405  629 VARDSGAVVVAKRDGVVEYVDASRI-----------VVRVEELDPGE-------DGVDIYnLIKFQRSNQNTCINQRPIV 690
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  657 EANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFEDAVLVSERLVYDDVFTSIHISRYEVsTAR-LREGQEYF 735
Cdd:PRK00405  691 KVGDRVEKGDVLADGPSTDNGELALGQNVLVAFMPWNGYNFEDAILISERLVKEDVFTSIHIEEYEI-EARdTKLGPEEI 769
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  736 TNQVD-------RNqyLDEFGVVKIGTWVEAGDVLVGKISPQPDSDNDPESRLLRAIFGGVARNTKTTSYCLSSGVSGRI 808
Cdd:PRK00405  770 TRDIPnvseealRN--LDESGIVRIGAEVKPGDILVGKVTPKGETELTPEEKLLRAIFGEKARDVKDTSLRVPHGEEGTV 847
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  809 LDVRcEFKRQTKNIEDES--IEStgsVYVYLVEKRRLQVGDKVAGRHGNKGIVSNILPRVDMPYLQSGKALDMVLNPLGV 886
Cdd:PRK00405  848 IDVK-VFTRIEQGDELPPgvNKL---VKVYIAQKRKIQVGDKMAGRHGNKGVVSRILPVEDMPYLEDGTPVDIVLNPLGV 923
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  887 PSRMNVGQIFECLLGLAANTLKQNFKVLPFDEMHGAEVSRgfvyhYLYKSRLltqqkwlfkpNSPGKSIVFDGRTGLNFD 966
Cdd:PRK00405  924 PSRMNIGQILETHLGWAAKGLGIKFATPVFDGAKEEEIKE-----LLEEAGL----------PEDGKTTLYDGRTGEPFD 988
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  967 QPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWALEGFGAAYVLQELLTIKSDDMIGRN 1046
Cdd:PRK00405  989 RPVTVGYMYMLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVVGRT 1068
                        1130      1140      1150
                  ....*....|....*....|....*....|....*..
gi 113170437 1047 RAFMSMIRGTLLPKSGIPESFKVLVSELRGLCLDMSI 1083
Cdd:PRK00405 1069 KVYEAIVKGENIPEPGIPESFNVLVKELQSLGLDVEL 1105
rpoB TIGR02013
DNA-directed RNA polymerase, beta subunit; This model describes orthologs of the beta subunit ...
10-1083 0e+00

DNA-directed RNA polymerase, beta subunit; This model describes orthologs of the beta subunit of Bacterial RNA polymerase. The core enzyme consists of two alpha chains, one beta chain, and one beta' subunit. [Transcription, DNA-dependent RNA polymerase]


Pssm-ID: 273928 [Multi-domain]  Cd Length: 1065  Bit Score: 1240.70  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    10 LPNFLDSQRDSFRYFLET----------GIREELDFFSPIvgqslgssskrpTDRFISVSFHSKDFYFKKPHYTPQEAVQ 79
Cdd:TIGR02013   17 VPNLLEIQLDSYDWFLQQdtppekrkeeGLEEVFKSIFPI------------EDYTGNIELEYLSYRLGEPKYSVEECKE 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    80 KLGTYKSSLIVPVHVYSKYLNLNATF---PVAFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQFD--KQGNRTH 154
Cdd:TIGR02013   85 RGLTYSAPLKVKLRLINKEEDGTKEIkeqDVYMGDIPLMTDRGTFIINGAERVVVSQLHRSPGVFFSSEKDttKSGKVLF 164
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   155 LVSFLSAYGSWLRFETDKKGVVFAHIDNLRKVPVTVFLQALGFSMDT-IVGALKYPEALDPTLkEVDWKLTTDEAILLLM 233
Cdd:TIGR02013  165 SARIIPYRGSWLEFETDKKDVLYVRIDRKRKLPATVLLRALGYTIDTlILNRLGSGEYIRNTL-RKDPTNSEEEALVEIY 243
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   234 SRLFPNRPATVLRGRKFLFNQFFNPRRYSLSDVGRKRVNQKFRMRSKTKHLTLTPQDALAALDYLLRCENGETEfLDDID 313
Cdd:TIGR02013  244 RKLRPGEPPTVEAARSLLENLFFDPKRYDLGRVGRYKLNKKLGLDVPESIGVLTKEDIIATIKYLIKLRNGKGE-IDDID 322
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   314 HLKNRRARLAGELIQTQFRLGLNRLERVIYNRISDENILRKTPGalgslnSLIRTQVLASVFQEFFGSNQLSQFMDQTNP 393
Cdd:TIGR02013  323 HLGNRRIRSVGELLQNQFRVGLARMERIVRERMSTQDTDTLTPQ------DLINAKPISAAIKEFFGSSQLSQFMDQTNP 396
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   394 LAEITHKRRLSSLGPGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYKLISESNT 473
Cdd:TIGR02013  397 LAELTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLSTYARVNEYGFIETPYRKVKDGKVV 476
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   474 PDRNGFFLlSAFYEEDTVVAQGDVDL---SNF---RIPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPFLEHDDAN 547
Cdd:TIGR02013  477 VTDEIDYL-TADEEDNYVIAQANAPLdenGRFvedLVVARYRGEITLVSPDQVDYMDVSPKQVVSVAASLIPFLEHDDAN 555
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   548 RALMGSNMQRQAVSLLRSERPFVGTGLEAHVTRDIGATIVAKQNSYISYVDAQRIdyftpVIGDTNLIDYQNlTAEDVFA 627
Cdd:TIGR02013  556 RALMGSNMQRQAVPLLRSEAPLVGTGMEAKVARDSGAVIVAKRGGVVEYVDAKRI-----VIRYDEDEEEPD-GGIDIYR 629
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   628 snqfkhntiwLTSYQRSNQDTCLNHKPLVEANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFEDAVLVSERL 707
Cdd:TIGR02013  630 ----------LLKYQRSNQDTCINQRPIVSVGDRVEAGDVLADGPSTDLGELALGRNVLVAFMPWNGYNYEDAILISERL 699
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   708 VYDDVFTSIHISRYEVSTARLREGQEYFTNQVD-------RNqyLDEFGVVKIGTWVEAGDVLVGKISPQPDSDNDPESR 780
Cdd:TIGR02013  700 VKDDVFTSIHIEEYEVEARDTKLGPEEITRDIPnvseealRN--LDENGIVRIGAEVKAGDILVGKVTPKGETELTPEEK 777
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   781 LLRAIFGGVARNTKTTSYCLSSGVSGRILDVRcEFKRQTKNIEDESIEStgSVYVYLVEKRRLQVGDKVAGRHGNKGIVS 860
Cdd:TIGR02013  778 LLRAIFGEKARDVRDTSLRVPPGVEGTVIDVK-VFSREQGDELPPGVNK--LVKVYIAQKRKIQVGDKMAGRHGNKGVVS 854
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   861 NILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTLkqnfkvlpfdEMHGAEVSRGFVYHYLYKSRLLT 940
Cdd:TIGR02013  855 KILPIEDMPFLEDGTPVDIVLNPLGVPSRMNIGQILETHLGWAGKRL----------GRKGVPIATPVFDGASEEEIKEY 924
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   941 QQKWLFKPNspGKSIVFDGRTGLNFDQPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVW 1020
Cdd:TIGR02013  925 LEKAGLPRD--GKVRLYDGRTGEQFDRPVTVGYMYMLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVW 1002
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 113170437  1021 ALEGFGAAYVLQELLTIKSDDMIGRNRAFMSMIRGTLLPKSGIPESFKVLVSELRGLCLDMSI 1083
Cdd:TIGR02013 1003 ALEAYGAAYTLQEMLTVKSDDVVGRTKAYEAIVKGENVPEPGIPESFNVLIKELQSLGLDIEL 1065
RpoB COG0085
DNA-directed RNA polymerase, beta subunit/140 kD subunit [Transcription]; DNA-directed RNA ...
10-1083 0e+00

DNA-directed RNA polymerase, beta subunit/140 kD subunit [Transcription]; DNA-directed RNA polymerase, beta subunit/140 kD subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 439855 [Multi-domain]  Cd Length: 1001  Bit Score: 1218.80  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   10 LPNFLDSQRDSFRYFLETGIREELDFFSPIvgqslgssskRPTDRFISVSFhsKDFYFKKPHYTPQEAVQKLGTYKSSLI 89
Cdd:COG0085    13 LPNLLEIQLDSFNWFLEEGLQEIFDEISPI----------EDFTGNLSLEF--GDYRLGEPKYTPEECKERDLTYAAPLY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   90 VPVHVYSKYLNLNATFPVAFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQFDKQGNRTHLVSFLSAYGSWLRFE 169
Cdd:COG0085    81 VKVRLVNKETGEIKEQEVFMGDFPLMTDSGTFIINGTERVIVSQLVRSPGVYFVEEEDKSGKDLYSAKVIPSRGAWLEFE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  170 TDKKGVVFAHIDNLRKVPVTVFLQALGFSMD----TIVGALKYPEALDPTLKEvDWKLTTDEAILLLMSRLFPNRPATVL 245
Cdd:COG0085   161 TDKDGTIYVRIDRKRKIPVTVLLRALGLETDeeilEAFGDDPIQEYILATLEK-DNTKTQEEALLEIYRKLRPGEPPTIE 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  246 RGRKFLFNQFFNPRRYSLSDVGRKRVNQKFRMRSKTKHLTLTPQDALAALDYLLRCENGEtEFLDDIDHLKNRRARLAGE 325
Cdd:COG0085   240 RAEQLLDNLFFDPKRYDLAHVGRYKINKKLGLDVPPEDRVLTAEDIVATIKYLLELHLGE-REPDDIDHLGNRRVRLVGE 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  326 LIQTQFRLGLNRLERVIYNRISDENILRKTPgalgslNSLIRTQVLASVFQEFFGSNQLSQFMDQTNPLAEITHKRRLSS 405
Cdd:COG0085   319 LLQNQFRVGLSRMERVVRERMTTQDVEAITP------QSLINIRPVVAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  406 LGPGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYKLIsesntpdrNGFF----- 480
Cdd:COG0085   393 LGPGGLSRERAGFEVRDVHPSHYGRMCPIETPEGPNIGLIGSLALYARVNEYGFIETPYRKVE--------NGKVtdeie 464
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  481 LLSAFYEEDTVVAQGDVDLSNF------RIPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPFLEHDDANRALMGSN 554
Cdd:COG0085   465 YLTADEEENYYIAQANAPLDEDgnfleeRVLVRYRGEEVLVPPEEVDYMDVSPKQIVSVATSLIPFLEHDDANRALMGAN 544
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  555 MQRQAVSLLRSERPFVgtgleahvtrdigativakqnsyisyvdaqridyftpvigdtnlidyqnltaedvfasnqfkhn 634
Cdd:COG0085   545 MQRQAVPLLRPEAPLL---------------------------------------------------------------- 560
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  635 TIWLTSYQRSNQDTCLNHKPLVEANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFEDAVLVSERLVYDDVFT 714
Cdd:COG0085   561 HYPLQKFQRSNQGTCINQRPIVRVGDRVEKGDVLADGPATDNGELALGQNLLVAFMPWEGYNYEDAIIISERLVKDDVLT 640
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  715 SIHISRYEVSTARLREGQEYFTN-------QVDRNqyLDEFGVVKIGTWVEAGDVLVGKISPQPDSDNDPESRLLRAIFG 787
Cdd:COG0085   641 SIHIEEYEIEARDTKLGPEEITRdipnvseEALRN--LDEDGIIRIGAEVKGGDILVGKVTPKGETELTPEERLLRAIFG 718
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  788 GVARNTKTTSYCLSSGVSGRILDVRcEFKRqtkniEDESIESTGS---VYVYLVEKRRLQVGDKVAGRHGNKGIVSNILP 864
Cdd:COG0085   719 EKAREVRDTSLRVPHGEKGKVIDVK-VFSR-----EEGDELPPGVnklVRVYVAQKRKIEVGDKLAGRHGNKGVISRILP 792
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  865 RVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTLKQNFKVLPFDEMHGAEVSRgfvyhYLYKSRLltqqkw 944
Cdd:COG0085   793 QEDMPFLEDGTPVDIVLNPLGVPSRMNVGQVLETHLGWAAALLGRRVATPVFDGAPEEEIRE-----LLEKAGL------ 861
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  945 lfkpNSPGKSIVFDGRTGLNFDQPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWALEG 1024
Cdd:COG0085   862 ----PPDGKEVLYDGRTGEPFDNPVTVGYMYYLKLHHMVDDKIHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEA 937
                        1050      1060      1070      1080      1090
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 113170437 1025 FGAAYVLQELLTIKSDDMIGRNRAFMSMIRGTLLPKSGIPESFKVLVSELRGLCLDMSI 1083
Cdd:COG0085   938 YGAAYTLQERLTIKSDDVCGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLGLDVEV 996
rpoB CHL00207
RNA polymerase beta subunit; Provisional
7-1087 0e+00

RNA polymerase beta subunit; Provisional


Pssm-ID: 214397 [Multi-domain]  Cd Length: 1077  Bit Score: 1139.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    7 NSALPNFLDSQRDSFRYFLETGIREELDFFSPIVGQSlgssskrptdRFISVSFHSKDFYFKKPHYTPQEAVQKLGTYKS 86
Cdd:CHL00207    4 NFALPDFLEIQRTSFCWFLNEGLNEELNIFSKIFDYT----------GNLELLLFGKNYKLKYPKYNLLSAKSYDSNYSI 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   87 SLIVPVHVYSKYLNLNATFPVAFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQFDKQGNRTHLVSFLSAYGSWL 166
Cdd:CHL00207   74 QIYLPLKFINLKTNKIKFINYLIGNLPKMTQRGTFIINGLERVIVSQIIRSPGIYFKKEIKKNSNKIYSATLIPNRGSWI 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  167 RFETDKKGVVFAHIDNLRKVPVTVFLQALGFSMDTIVGALKYP--EALDPTLKEVDWKLTTDEAILLLMSRLFPNRPATV 244
Cdd:CHL00207  154 KFELDKNKEIWIRIDKNRKKPLIIFLKALGLTDQDIYSRLTKSefLKKLKPILLNSNSYTNEEILLEIYKNLSPIEPATV 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  245 LRGRKFLFNQFFNPRRYSLSDVGRKRVNQKFRMRSKTKHLTLTPQDALAALDYLLRCENGETEFlDDIDHLKNRRARLAG 324
Cdd:CHL00207  234 NDANQNLFSRFFDPKNYDLGKVGRYKINNKLNLNIPERVRNLTYEDILSIIDKLINLKINKGNF-DDIDHLKNRRVRSVG 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  325 ELIQTQFRLGLNRLERVIYNRISDENILRKTPgalgslNSLIRTQVLASVFQEFFGSNQLSQFMDQTNPLAEITHKRRLS 404
Cdd:CHL00207  313 ELLQNQFRIGLKRLERILRNRMTICDIDSLSK------FNLINPKPLIALIREFFGSSQLSQYMDQTNPLSELTHKRRIS 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  405 SLGPGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYKLISESNTPDRNGFFLlSA 484
Cdd:CHL00207  387 ILGPGGLDKDRISFAVRDIHPSHYGRICPIETPEGPNCGLIGSLATNARINKFGFIETPFYKVINGKVKKFGNPIYL-TA 465
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  485 FYEEDTVVAQGDVDL------SNFRIPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPFLEHDDANRALMGSNMQRQ 558
Cdd:CHL00207  466 DSEDLYRIAPNDINLnknnyfKKNIIPVRYKQEFKTVNPSKVDFIAISPIQVFSIAESLIPFLEHNDANRALMGSNMQRQ 545
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  559 AVSLLRSERPFVGTGLEAHVTRDIGATIVAKQNSYISYVDAQRIdyftpVIGDTN--LIDYqnltaedvfasnqfkhnti 636
Cdd:CHL00207  546 AVPLLYPEKPIVGTGYEKQIALDSGMTIISLTEGIVVSVSAYKI-----IIQDDNnrYIHY------------------- 601
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  637 WLTSYQRSNQDTCLNHKPLVEANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFEDAVLVSERLVYDDVFTSI 716
Cdd:CHL00207  602 YLQKYQRSNQNTCINYRPIVWVGEKINIGQILADGSDIDNSELALGQNVLVAYMPWEGYNFEDAILINKRLVYEDLFTSI 681
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  717 HISRYEVSTARLREGQEYFTNQVDRNQY-----LDEFGVVKIGTWVEAGDVLVGKISPQPDSDNDPESRLLRAIFGGVAR 791
Cdd:CHL00207  682 HIEKYEIELRQTKLGSEEITRNIPNVSEyslknLDENGIISIGSKVLAGDILVGKITPKGESDQLPEGKLLRAIFGEKAK 761
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  792 NTKTTSYCLSSGVSGRILDVRCeFKRQTKnieDESIESTG-SVYVYLVEKRRLQVGDKVAGRHGNKGIVSNILPRVDMPY 870
Cdd:CHL00207  762 DVKDTSLRMPNGGYGRVIKVEI-FSRSKG---DELKFGYYlKIRVFIAQIRKIQVGDKLAGRHGNKGIISRILPRQDMPY 837
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  871 LQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTLKQNFKVLPFDEMHGAEVSRGFVYHYLYKSRLLTQQKWLFKPNS 950
Cdd:CHL00207  838 LPDGTPPDIILNPLGVPSRMNVGQLFECLLGLAGDNLNKRFKILPFDEMYGSEYSRILINNKLNQASIKNNEYWLFNSYH 917
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  951 PGKSIVFDGRTGLNFDQPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWALEGFGAAYV 1030
Cdd:CHL00207  918 PGKMVLRDGRTGYKFKNPVTVGIAYMLKLIHLVDDKIHARTTGPYSLVTQQPLGGKAQHGGQRFGEMEVWALEAFGAAYT 997
                        1050      1060      1070      1080      1090
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 113170437 1031 LQELLTIKSDDMIGRNRAFMSMIRGTLLPKSGIPESFKVLVSELRGLCLDMSIARIN 1087
Cdd:CHL00207  998 LKELLTIKSDDMQGRNETLNAIVKGQPIPKPGTPESFKVLMRELQSLGLDIEAYKIE 1054
RNA_pol_B_RPB2 cd00653
RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. ...
13-1083 0e+00

RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase complex contains two related members of this family, in each case they are the two largest subunits.The clamp is a mobile structure that grips DNA during elongation.


Pssm-ID: 238353 [Multi-domain]  Cd Length: 866  Bit Score: 769.81  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   13 FLDSQRDSFRYFLETGIREELDFFSPIVgqslgssskrPTDRFISVSFHSKDFYFKKP---------HYTPQEAVQKLGT 83
Cdd:cd00653     1 LVKQQIDSFNYFLNVGLQEIVKSIPPIT----------DTDDDGRLKLKFGDIYLGKPkveeggvtrKLTPNECRLRDLT 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   84 YKSSLIVPVHVYSKYLNLNATFPVAFCDLPLMTEH------------------------GTFILNGSPRVIVHQIVRCPG 139
Cdd:cd00653    71 YSAPLYVDIRLTVNDKGKIKEQEVFIGEIPIMLRSklcnlngltpeeliklgecpldpgGYFIINGTEKVIINQEQRSPN 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  140 VYLKpqFDKQGNRTHLVSFLSAY----GSWLRFETD-KKGVVFAHIDNLRKvpvtvflqalgfsmdtivgalkypealdp 214
Cdd:cd00653   151 VIIV--EDSKGKRIYTKTSIPSYspyrGSWLEVKSDkKKDRIYVRIDLKRQ----------------------------- 199
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  215 tlkevdwklttDEAilllmsrlfpnrpatvlrgRKFLFNQFFnprryslsdvgrkrvnqkfrmrsktkhltltpqDALAA 294
Cdd:cd00653   200 -----------EEA-------------------LKYIGKRFE---------------------------------DLIYM 216
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  295 LDYLLRCENGETEfLDDIDHLKNRRARLAGELIQTQFRLGLNRLERVIYNRISDENILRKTPgalgSLNSLIRTQVLASV 374
Cdd:cd00653   217 IRKLILLVLGKGK-LDDIDHLGNKRVRLAGELLQNLFRSGLKRLEREVKEKLQKQLSKKKDL----TPQLLINSKPITSG 291
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  375 FQEFFGSNQ------------LSQFMDQTNPLAEITHKRRLSSlgpGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNA 442
Cdd:cd00653   292 IKEFLATGNwgskrflmqrsgLSQVLDRLNPLSELSHKRRISS---LGLFRERKGFEVRDLHPSHWGRICPIETPEGENC 368
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  443 GLVGSIATFTQINknGFLESPYYKLISESntpdrngffllsafyeedtvvaqgdvdlsnfriptrnksqftenTVQEInf 522
Cdd:cd00653   369 GLVKNLALMARIS--GRIERPYRIVEKEV--------------------------------------------THIEI-- 400
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  523 lglCPIQFMSIATSLIPFLEHDDANRALMGSNMQRQAV----------------SLLRSERPFVGTGLEAHVtrdigati 586
Cdd:cd00653   401 ---SPSQILSVAASLIPFPEHNQSPRNLYQSNMQKQAVgtpalnqqyrmdtklyLLLYPQKPLVGTGIEEYI-------- 469
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  587 vakqnsyisyvdaqridyftpvigdtnlidyqnltaedvfasnqfkhntiwltsyqrsnqdtclnhkplveantwveagd 666
Cdd:cd00653       --------------------------------------------------------------------------------
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  667 cladnaatAKGELALGRNILIGYMPWEGYNFEDAVLVSERLVYDDVFTSIHISRYEVSTARLREGQEYFTNQVDRN---- 742
Cdd:cd00653   470 --------AFGELPLGQNAIVAVMSYSGYNFEDAIIINKSSVDRGFFRSIHYKKYEIELRKTKNGPEEITRGDIPNvsee 541
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  743 --QYLDEFGVVKIGTWVEAGDVLVGKISPQPDSDNDPesrllraIFGGVARNTKTTSYCLSSGVSGRILDVRCeFKRQTK 820
Cdd:cd00653   542 klKNLDEDGIIRPGARVEPGDILVGKITPKGETESTP-------IFGEKARDVRDTSLKYPGGEKGIVDDVKI-FSRELN 613
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  821 NIEDESIEstgsvyVYLVEKRRLQVGDKVAGRHGNKGIVSNILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLL 900
Cdd:cd00653   614 DGGNKLVK------VYIRQKRKPQIGDKFASRHGQKGVISKILPQEDMPFTEDGIPPDIILNPHGFPSRMTIGQLLESLL 687
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  901 GLAANTLKQNFKVLPFDEMHGAEVSRGFVYHYLyksrlltqqkwlfkpNSPGKSIVFDGRTGLNFDQPVTVGYPYILKLV 980
Cdd:cd00653   688 GKAGALLGKFGDATPFDGAEEEDISELLGEAGL---------------NYYGKEVLYDGRTGEPLEAPIFVGPVYYQRLK 752
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  981 HLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWALEGFGAAYVLQELLTIKSDDMIGRNRAFMSMI------- 1053
Cdd:cd00653   753 HMVDDKIHARSTGPYSLLTRQPLKGRSRGGGQRFGEMERDALIAHGAAYLLQERLTIKSDDVVARVCVKCGIIlsanlcr 832
                        1130      1140      1150
                  ....*....|....*....|....*....|...
gi 113170437 1054 ---RGTLLPKSGIPESFKVLVSELRGLCLDMSI 1083
Cdd:cd00653   833 lckKGTNISKVGIPYAFKLLFQELQSMNIDPRL 865
PRK09603 PRK09603
DNA-directed RNA polymerase subunit beta/beta';
6-1083 0e+00

DNA-directed RNA polymerase subunit beta/beta';


Pssm-ID: 181983 [Multi-domain]  Cd Length: 2890  Bit Score: 769.09  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    6 QNSALPNFLDSQRDSFRYFL------ETGIREELDFFSPIvgqslGSSSKRPTDRFISVSFhskdfyfKKPHYTPQEAVQ 79
Cdd:PRK09603   20 TDLEVPNLLLLQRDSYDSFLyskdgkESGIEKVFKSIFPI-----QDEHNRITLEYAGCEF-------GKSKYTVREAME 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   80 KLGTYKSSLIVPVHVY-------------SKYLNLNATFpvaFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQf 146
Cdd:PRK09603   88 RGITYSIPLKIKVRLIlwekdtksgekngIKDIKEQSIF---IREIPLMTERTSFIINGVERVVVNQLHRSPGVIFKEE- 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  147 DKQGNRTHLV---SFLSAYGSWLRFETDKKGVVFAHIDNLRKVPVTVFLQALGFSMDTIV-------------------- 203
Cdd:PRK09603  164 ESSTSLNKLIytgQIIPDRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIkmfyplvkvryendkylipf 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  204 -----------------------------------------GALKYP-----------------EALDPTLKEVD----- 220
Cdd:PRK09603  244 asldanqrmefdlkdpqgkiillagkkltsrkikelkenhlEWVEYPmdillnrhlaepvmvgkEVLLDMLTQLDknkle 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  221 ---------------WKLTTDEAIL------------------------LLMSRLF----PNRPATVLRGRKFLFNQFFN 257
Cdd:PRK09603  324 kihdlgvqefviindLALGHDASIIhsfsadseslkllkqtekiddenaLAAIRIHkvmkPGDPVTTEVAKQFVKKLFFD 403
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  258 PRRYSLSDVGRKRVNQKFRMRSKTKHLTLTPQDALAALDYLLRCENGETEfLDDIDHLKNRRARLAGELIQTQFRLGLNR 337
Cdd:PRK09603  404 PERYDLTMVGRMKMNHKLGLHVPDYITTLTHEDIITTVKYLMKIKNNQGK-IDDRDHLGNRRIRAVGELLANELHSGLVK 482
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  338 LERVIYNRISDENilrktpGALGSL--NSLIRTQVLASVFQEFFGSNQLSQFMDQTNPLAEITHKRRLSSLGPGGLNRDR 415
Cdd:PRK09603  483 MQKTIKDKLTTMS------GAFDSLmpHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKDR 556
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  416 AGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYKLISESNTPDrngFFLLSAFYEEDTVVAQG 495
Cdd:PRK09603  557 VGFEARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGFIEAPYKKVVDGKVVGE---TIYLTAIQEDSHIIAPA 633
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  496 DVDLSNFR------IPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPFLEHDDANRALMGSNMQRQAVSLLRSERPF 569
Cdd:PRK09603  634 STPIDEEGnilgdlIETRVEGEIVLNEKSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPI 713
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  570 VGTGLEAHVTRDIGATIVAKQNSYISYVDAQRIdyftpvigdtnlidyqNLTAEDvfasnqfkHNTIWLTSYQ-----RS 644
Cdd:PRK09603  714 VGTGIEKIIARDSWGAIKANRAGVVEKIDSKNI----------------YILGEG--------KEEAYIDAYSlqknlRT 769
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  645 NQDTCLNHKPLVEANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFEDAVLVSERLVYDDVFTSIHISRYEVS 724
Cdd:PRK09603  770 NQNTSFNQVPIVKVGDKVEAGQIIADGPSMDRGELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTSTHIYEKEVD 849
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  725 TARLREGQEYFTNQV-----DRNQYLDEFGVVKIGTWVEAGDVLVGKISPQPDSDNDPESRLLRAIFGGVARNTKTTS-Y 798
Cdd:PRK09603  850 ARELKHGVEEFTADIpdvkeEALAHLDESGIVKVGTYVSAGMILVGKTSPKGEIKSTPEERLLRAIFGDKAGHVVNKSlY 929
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  799 CLSSgVSGRILDVRCEFKR------------------------------------------------------------- 817
Cdd:PRK09603  930 CPPS-LEGTVIDVKVFTKKgyekdarvlsayeeekakldmehfdrltmlnreellrvssllsqaileepfshngkdykeg 1008
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  818 --------------------------------QTKN-------------------IEDESIESTG---SVYVYLVEKRRL 843
Cdd:PRK09603 1009 dqipkeeiasinrftlaslvkkyskevqnhyeITKNnfleqkkvlgeeheeklsiLEKDDILPNGvikKVKLYIATKRKL 1088
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  844 QVGDKVAGRHGNKGIVSNILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTL------------KQNF 911
Cdd:PRK09603 1089 KVGDKMAGRHGNKGIVSNIVPVADMPYTADGEPVDIVLNPLGVPSRMNIGQILEMHLGLVGKEFgkqiasmledktKDFA 1168
                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  912 KVLPFDEMHGAEVSRG-------FVYHYLYKSRL-------------------LTQQKW-----LFKPNSPGKSIVFDGR 960
Cdd:PRK09603 1169 KELRAKMLEIANAINEkdpltihALENCSDEELLeyakdwskgvkmaipvfegISQEKFyklfeLAKIAMDGKMDLYDGR 1248
                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  961 TGLNFDQPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWALEGFGAAYVLQELLTIKSD 1040
Cdd:PRK09603 1249 TGEKMRERVNVGYMYMIKLHHLVDEKVHARSTGPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLKEMLTIKSD 1328
                        1370      1380      1390      1400
                  ....*....|....*....|....*....|....*....|...
gi 113170437 1041 DMIGRNRAFMSMIRGTLLPKSGIPESFKVLVSELRGLCLDMSI 1083
Cdd:PRK09603 1329 DIRGRENAYRAIAKGEQVGESEIPETFYVLTKELQSLALDINI 1371
PRK14844 PRK14844
DNA-directed RNA polymerase subunit beta/beta';
107-1087 0e+00

DNA-directed RNA polymerase subunit beta/beta';


Pssm-ID: 173305 [Multi-domain]  Cd Length: 2836  Bit Score: 709.47  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  107 VAFCDLPLMTEHGTFILNGSPRVIVHQIVRCPGVYLKPQFDKQGNRTHLV---SFLSAYGSWLRFETDKKGVVFAHIDNL 183
Cdd:PRK14844  142 VHFCELPMMTDKGTFIINGVEKVIVSQMHRSPGVFFDSDKGKTYNSGKLIysaRVIPYRGSWLDIEFDVKDHLYFRIDRK 221
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  184 RKVPVTVFLQALGFS----MDTIVGALKY------------PEAL---------------------------------DP 214
Cdd:PRK14844  222 RKLPISVLLKALGLSnndiLDRFYEKIKYikhkdgwkvpfvPDKFkgvrlpfdlmdvegnvllkanvritsrlakklyDN 301
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  215 TLKEV-----------------------------------DWK----LTTDEAILL----------LMSRLFPNRPAT-- 243
Cdd:PRK14844  302 ELKEYlvpfdsicglflaedlidsasstkilsagesikleDIKklelLSIDEISVLnidnlsvgpyILNTLFLDENMSyq 381
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  244 --------VLRG---------RKFLFNQFFNPRRYSLSDVGRKRVNQKFRMRSKTKHLTLTPQDALAALDYLLRCENGET 306
Cdd:PRK14844  382 dalyeiykVLRPgevpvleivEEFFRNLFFSPEYYDLSNIGRLKLNSYLGLNYDEDLTVLTHEDIIEIVRKIVLLRDGQG 461
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  307 EfLDDIDHLKNRRARLAGELIQTQFRLGLNRLERVIYNRISDENILRKTPgalgslNSLIRTQVLASVFQEFFGSNQLSQ 386
Cdd:PRK14844  462 S-VDDIDHLGNRRVRSVGEFIENQFRTGLLKLERAVVDSMSTSSLDKVSP------SDFINPKVLTNVLRDFFNSSQLSQ 534
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  387 FMDQTNPLAEITHKRRLSSLGPGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKNGFLESPYYK 466
Cdd:PRK14844  535 FMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGQNIGLINSLAIYARINKYGFIESPYRK 614
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  467 LISESNTpdrNGFFLLSAFYEEDTVVAQGDVDLSNFR------IPTRNKSQFTENTVQEINFLGLCPIQFMSIATSLIPF 540
Cdd:PRK14844  615 VVNRVVT---DQIEYLSAIDEGLYYIADTSAKLDENNcfvddmLYCRYAGSFVMVSSDQVSYIDVSPKQVISVAASLIPF 691
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  541 LEHDDANRALMGSNMQRQAVSLLRSERPFVGTGLEAHVTRDIGATIVAKQNSYISYVDAQRIdyftpVIG--DTNLIDYQ 618
Cdd:PRK14844  692 LENDDANRALMGSNMQRQAVPLLKPTAPLVATGMESFVASGSGAVVLAKRDGIVDSSDSNSI-----VIRafDKERVNYL 766
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  619 NLtaeDVFAsnqfkhntiwLTSYQRSNQDTCLNHKPLVEANTWVEAGDCLADNAATAKGELALGRNILIGYMPWEGYNFE 698
Cdd:PRK14844  767 DV---DIYH----------LRKFQRSNHNTCINQKPLVCVGDYVKEGDVIADGPAINSGELALGQNLLVAFMSWQGYNFE 833
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  699 DAVLVSERLVYDDVFTSIHISRYEVSTARLREGQEYFTNQV----DRNQY-LDEFGVVKIGTWVEAGDVLVGKISPQPDS 773
Cdd:PRK14844  834 DSIIISSEVVKKDLFTSIHIEEFECVVHDTPLGSEKITRAIpgvnEENLYhLDDSGIVKIGTRVGPGYILVGKVTPKPSL 913
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  774 DNDPESRLLRAIFGGVARNTKTTSYCLSSGVSGRILDVRCEFKR------------------------------------ 817
Cdd:PRK14844  914 SLPPETKLLMTIFGEKSFDCADSSLYTSPDVEGTVIDVQVFTRRgveenerallikqkeindfekerdyiinvtseyfyd 993
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  818 -------------------------------------QTKNIE---DESIEST----------------------GSVYV 835
Cdd:PRK14844  994 elkkllinsgsqdrekfdsiereqwwgiglknqsiseQVKSLKkdfDEKVSHAiaqfkrkveklhegydlpqgvsMSVKV 1073
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  836 YLVEKRRLQVGDKVAGRHGNKGIVSNILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTLKQ------ 909
Cdd:PRK14844 1074 FIAVKHSLQPGDKMAGRHGNKGVISRVVPVEDMPYLEDGTPVDIILNPLGVPSRMNVGQILETHVGWACKKLGEkvgnil 1153
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  910 -----------------------NFKVLPFDEMHGAEVS---------------------------------------RG 927
Cdd:PRK14844 1154 deinkiksafckgirslnddnftKFAAAYLDNKKIENIDddeitasvlntpnknalndelnelvenylnscksaysnlRN 1233
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  928 FVYH-YLYKSRL-------------LTQQKWLFKPNSP--------------------------GKSIVFDGRTGLNFDQ 967
Cdd:PRK14844 1234 FLIEvYSCGSNVsicnnirdisdnnLIEFARKLRDGIPvaapvfegpkdeqiaklfelagldnsGQAVLYDGCSGEKFDR 1313
                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  968 PVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWALEGFGAAYVLQELLTIKSDDMIGRNR 1047
Cdd:PRK14844 1314 KVTVGYMYMLKLHHLVDGKIHARSVGPYSLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDINGRVK 1393
                        1290      1300      1310      1320
                  ....*....|....*....|....*....|....*....|
gi 113170437 1048 AFMSMIRGTLLPKSGIPESFKVLVSELRGLCLDMSIARIN 1087
Cdd:PRK14844 1394 IYESIIKGDSNFECGIPESFNVMIKELRSLCLNVDLKQND 1433
RNA_pol_Rpb2_6 pfam00562
RNA polymerase Rpb2, domain 6; RNA polymerases catalyze the DNA dependent polymerization of ...
587-1008 7.08e-146

RNA polymerase Rpb2, domain 6; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). This domain represents the hybrid binding domain and the wall domain. The hybrid binding domain binds the nascent RNA strand / template DNA strand in the Pol II transcription elongation complex. This domain contains the important structural motifs, switch 3 and the flap loop and binds an active site metal ion. This domain is also involved in binding to Rpb1 and Rpb3. Many of the bacterial members contain large insertions within this domain, as region known as dispensable region 2 (DRII).


Pssm-ID: 459854 [Multi-domain]  Cd Length: 371  Bit Score: 441.20  E-value: 7.08e-146
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   587 VAKQNSYISYVDAQRIDYftpvigdtnlidyQNLTAEDvfasnqfKHNTIWLTSYQRSNQDT---CLNHKPLVEANTwVE 663
Cdd:pfam00562    1 VASLIPFVDHNQSPRNTY-------------QCAMGKQ-------AMGIYTLNKFYRSDQNTyvlCYPQKPLVKTGA-VE 59
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   664 AGDcladnaataKGELALGRNILIGYMPWEGYNFEDAVLVSERLVYDDVFTSIHISRYEVSTARLrEGQEYFTNQVDRN- 742
Cdd:pfam00562   60 AGG---------FGELPLGQNAIVAVMSYTGYNQEDAIIINKSSVDRGFFTSIHIKEIEARKTKL-GPIEEITRDIPNVs 129
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   743 ----QYLDEFGVVKIGTWVEAGDVLVGKISPqpdsdnDPESRLLRAIFGGVARNTKTTSYCLSSGVSGRILDVRcefkrq 818
Cdd:pfam00562  130 eealKKLDEDGIVRVGAEVKPGDILVGKVGP------TELTKLLRAIFGEKARDVKDTSLKVPPGEEGVVDDVI------ 197
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   819 tknIEDESIESTGSVYVYLVEKRRLQVGDKVAGRHGNKGIVSNILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFEC 898
Cdd:pfam00562  198 ---VFELPPGGIKMVKVYIRQKRKPEVGDKFASRHGQKGVVSRILPQEDMPFTEDGIPPDIILNPHGVPSRMTIGQLLET 274
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   899 LLGLAANTLKQNFKVLPFDemhGAEVSRGFVYHYLYKSRLltqqkwlfkpNSPGKSIVFDGRTGLNFDQPVTVGYPYILK 978
Cdd:pfam00562  275 HLGKAAALLGVFVDATPFD---GASTEVEDIGELLEKAGY----------NYYGKEVLYDGRTGEPFEAPIFVGPIYYQK 341
                          410       420       430
                   ....*....|....*....|....*....|
gi 113170437   979 LVHLVDDKIHARSTGPYSLVTQQPLGGRSK 1008
Cdd:pfam00562  342 LKHMVDDKIHARSTGPYSLLTRQPLGGRAR 371
PRK08565 PRK08565
DNA-directed RNA polymerase subunit B; Provisional
119-1083 2.51e-82

DNA-directed RNA polymerase subunit B; Provisional


Pssm-ID: 236291 [Multi-domain]  Cd Length: 1103  Bit Score: 291.09  E-value: 2.51e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  119 GTFILNGSPRVIVHQIVRCPGVYLKPQFDKQGNRTHLVSFLSA---YGSWLRFETDKKGVVFAHIDNLR-KVPVTVFLQA 194
Cdd:PRK08565  141 GYFIINGSERVIVSQEDLAPNRVLVDKGEAGSSITHTAKVISSragYRAQVTVERRKDGTIYVSFPAVPgKIPFVILMRA 220
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  195 LGFSMDT-IVGALKY-PE---ALDPTLKEV-DWKLTTDEAILLLMSRLFPNRPATV--LRGRKFLFNQFFnPrryslsdv 266
Cdd:PRK08565  221 LGLETDRdIVYAVSLdPEiqqELLPSLEQAsSIAATVEDALDYIGKRVAIGQPREYriERAEQILDKYLL-P-------- 291
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  267 grkrvnqkfrmrsktkHLTLTPQDALAALDYLLRCENGETEFL------DDIDHLKNRRARLAGELIQTQFRLGLNRLER 340
Cdd:PRK08565  292 ----------------HLGTSPEDRIKKAYFLGQMASKLLELYlgrrepDDKDHYANKRLRLAGDLLAELFRVAFKQLVK 355
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  341 VIYNRIsdENILRKTPGAlgSLNSLIRTQVLASVFQEFF-------GSNQLSQFMDQTNPLAEITHKRRLSSlgpgGLNR 413
Cdd:PRK08565  356 DLKYQL--EKSYARGRKL--DLRAIVRPDIITERIRHALatgnwvgGRTGVSQLLDRTNYLSTLSHLRRVVS----PLSR 427
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  414 DRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINkNGFLESPYYKLI-----------SESNTPDR-----N 477
Cdd:PRK08565  428 GQPHFEARDLHGTQWGRICPFETPEGPNCGLVKNLALMAQIS-VGVDEEEVEEILyelgvvpveeaREEEYISWsrvylN 506
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  478 GFFL---------------------LS-----AFYEEDT------------------VVAQGDVDLSNFRIPTRNKSQFT 513
Cdd:PRK08565  507 GRLIgyhpdgeelaekirelrrsgkISdevnvAYIETGEinevyvncdsgrvrrpliVVENGKPKLTREHVEKLKKGELT 586
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  514 ------------------ENTV---------QEINFLGLCPIQFMSIATSLIPFLEHDDANRALMGSNMQRQAVSL---- 562
Cdd:PRK08565  587 fddlvkmgvieyldaeeeENAYvaldpedltPEHTHLEIWPPAILGITASIIPYPEHNQSPRNTYQAAMAKQSLGLyaan 666
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  563 --LRS----------ERPFVGT-GLEahvtrdigativakqnsyisyvdaqridyftpvigdtnLIDYQNLTAedvfasn 629
Cdd:PRK08565  667 frIRTdtrghllhypQRPLVQTrALE--------------------------------------IIGYNDRPA------- 701
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  630 qfkhntiwltsyqrsnqdtclnhkplveantwveagdcladnaatakgelalGRNILIGYMPWEGYNFEDAVLVS----E 705
Cdd:PRK08565  702 ----------------------------------------------------GQNAVVAVLSYTGYNIEDAIIMNkasiE 729
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  706 RLVYDDVFTSIHIS-----------RYEVSTARLR--EGQEYFTNqvdrnqyLDEFGVVKIGTWVEAGDVLVGKISPqpd 772
Cdd:PRK08565  730 RGLARSTFFRTYETeerkypggqedKIEIPEPNVRgyRGEEYYRK-------LDEDGIVSPEVEVKGGDVLIGKTSP--- 799
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  773 sdndPesRLL--RAIFGGVARNTKTTSYCLSSGVSGRILDVrcefkrqtknIEDESIESTGSVYVYLVEKRRLQVGDKVA 850
Cdd:PRK08565  800 ----P--RFLeeLEELSLGLQERRDTSVTVRHGEKGIVDTV----------LITESPEGNKLVKVRVRDLRIPELGDKFA 863
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  851 GRHGNKGIVSNILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGLAANTLKQNFKVLPF-----DEMHGAEVS 925
Cdd:PRK08565  864 SRHGQKGVIGMLVPQEDMPFTEDGIVPDLIINPHAIPSRMTVGQLLESIAGKVAALEGRFVDATPFygepeEELRKELLK 943
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  926 RGFvyhylyksrlltqqkwlfKPNspGKSIVFDGRTGLNFDQPVTVGYPYILKLVHLVDDKIHARSTGPYSLVTQQPLGG 1005
Cdd:PRK08565  944 LGY------------------KPD--GTEVMYDGRTGEKIKAPIFIGVVYYQKLHHMVADKIHARARGPVQILTRQPTEG 1003
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437 1006 RSKKGGQRLGEMEVWALEGFGAAYVLQELLTIKSDD----------MIG----RNRAFMSMIRG--TLLPKSGIPESFKV 1069
Cdd:PRK08565 1004 RAREGGLRFGEMERDCLIGHGAAMLLKERLLDSSDKttiyvcelcgHIAwydrRKNKYVCPIHGdkGNISPVEVSYAFKL 1083
                        1130
                  ....*....|....
gi 113170437 1070 LVSELRGLCLDMSI 1083
Cdd:PRK08565 1084 LLQELMSMGISPRL 1097
rpoB_arch TIGR03670
DNA-directed RNA polymerase subunit B; This model represents the archaeal version of ...
682-1083 1.64e-60

DNA-directed RNA polymerase subunit B; This model represents the archaeal version of DNA-directed RNA polymerase subunit B (rpoB) and is observed in all archaeal genomes.


Pssm-ID: 274713 [Multi-domain]  Cd Length: 599  Bit Score: 218.36  E-value: 1.64e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   682 GRNILIGYMPWEGYNFEDAVLVSE--------RLVYDDVFTSIHI-------SRYEVSTARLR--EGQEYFTNqvdrnqy 744
Cdd:TIGR03670  198 GQNFVVAVMSYEGYNIEDALIMNKasierglaRSTFFRTYEAEERrypggqeDRFEIPEPDVRgyRGEEAYKH------- 270
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   745 LDEFGVVKIGTWVEAGDVLVGKISPqpdsdndpeSRLL--RAIFGGVARNTKTTSYCLSSGVSGrILDvrcefkrqtKNI 822
Cdd:TIGR03670  271 LDEDGIVYPEVEVKGGDVLIGKTSP---------PRFLeeLREFGLVTERRRDTSVTVRHGEKG-IVD---------KVI 331
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   823 EDESIESTGSVYVYLVEKRRLQVGDKVAGRHGNKGIVSNILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLGL 902
Cdd:TIGR03670  332 ITETEEGNKLVKVRVRDLRIPELGDKFASRHGQKGVIGMIVPQEDMPFTEDGIVPDLIINPHAIPSRMTVGQLLEMIAGK 411
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   903 AANTLKQNFKVLPFDEMHGAEVsrgfvyhylyKSRLLtqqKWLFKPNspGKSIVFDGRTGLNFDQPVTVGYPYILKLVHL 982
Cdd:TIGR03670  412 VAALEGRRVDGTPFEGEPEEEL----------RKELL---KLGFKPD--GKEVMYDGITGEKLEAEIFIGVIYYQKLHHM 476
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   983 VDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWALEGFGAAYVLQELLTIKSDD----------MIG-----RNR 1047
Cdd:TIGR03670  477 VADKIHARSRGPVQVLTRQPTEGRAREGGLRFGEMERDVLIGHGAAMLLKERLLDESDKyvvyvcencgHIAwedkrKGT 556
                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 113170437  1048 AFMSmIRG--TLLPKSGIPESFKVLVSELRGLCLDMSI 1083
Cdd:TIGR03670  557 AYCP-VCGetGDISPVEMSYAFKLLLDELKSLGISPRL 593
PRK07225 PRK07225
DNA-directed RNA polymerase subunit B'; Validated
682-1080 2.38e-56

DNA-directed RNA polymerase subunit B'; Validated


Pssm-ID: 235972 [Multi-domain]  Cd Length: 605  Bit Score: 206.35  E-value: 2.38e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  682 GRNILIGYMPWEGYNFEDAVLVS----ERLVYDDVF----------------TSIHISRYEVSTARlreGQEYFTNqvdr 741
Cdd:PRK07225  204 GQNFVVAVMSYEGYNIEDALIMNkasiERGLGRSHFfrtyegeerrypggqeDRFEIPDKDVRGYR---GEEAYRH---- 276
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  742 nqyLDEFGVVKIGTWVEAGDVLVGKISPqPDSDNDPEsrllraIFGGVARNTKTTSYCLSSGVSGrILDvrcefkrqtKN 821
Cdd:PRK07225  277 ---LDEDGLVNPETEVKEGDVLIGKTSP-PRFLEEPD------DFGISPEKRRETSVTMRSGEEG-IVD---------TV 336
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  822 IEDESIESTGSVYVYLVEKRRLQVGDKVAGRHGNKGIVSNILPRVDMPYLQSGKALDMVLNPLGVPSRMNVGQIFECLLG 901
Cdd:PRK07225  337 ILTETEEGSRLVKVRVRDLRIPELGDKFASRHGQKGVIGLIVPQEDMPFTESGVVPDLIINPHAIPSRMTVGHVLEMIGG 416
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  902 LAANTLKQNFKVLPF-----DEMHGAEVSRGFVYHylyksrlltqqkwlfkpnspGKSIVFDGRTGLNFDQPVTVGYPYI 976
Cdd:PRK07225  417 KVGSLEGRRVDGTAFsgedeEDLREALEKLGFEHT--------------------GKEVMYDGITGEKIEAEIFVGVIYY 476
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  977 LKLVHLVDDKIHARSTGPYSLVTQQPLGGRSKKGGQRLGEMEVWALEGFGAAYVLQELLTIKSDD----------MIG-- 1044
Cdd:PRK07225  477 QKLHHMVANKLHARSRGPVQVLTRQPTEGRAREGGLRFGEMERDVLIGHGAAMLLKERLLDESDKveiyvcakcgMIAiy 556
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 113170437 1045 ---RNRAFMSmIRG--TLLPKSGIPESFKVLVSELRGLCLD 1080
Cdd:PRK07225  557 dkkRNRKYCP-ICGeeTDIYPVEMSYAFKLLLDELKSLGIA 596
RNA_pol_Rpb2_3 pfam04565
RNA polymerase Rpb2, domain 3; RNA polymerases catalyze the DNA dependent polymerization of ...
386-453 3.36e-30

RNA polymerase Rpb2, domain 3; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Domain 3, s also known as the fork domain and is proximal to catalytic site.


Pssm-ID: 428011 [Multi-domain]  Cd Length: 67  Bit Score: 113.78  E-value: 3.36e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 113170437   386 QFMDQTNPLAEITHKRRLSSlGPGGLNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQ 453
Cdd:pfam04565    1 QVLDRTNYLSTLSHLRRVNS-PRGGLFREMKTTEVRDLHPSHWGRICPVETPEGPNCGLVKHLALYAR 67
RNA_pol_Rpb2_1 pfam04563
RNA polymerase beta subunit; RNA polymerases catalyze the DNA dependent polymerization of RNA. ...
17-346 4.51e-28

RNA polymerase beta subunit; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). This domain forms one of the two distinctive lobes of the Rpb2 structure. This domain is also known as the protrusion domain. The other lobe (pfam04561) is nested within this domain.


Pssm-ID: 367994 [Multi-domain]  Cd Length: 396  Bit Score: 117.87  E-value: 4.51e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    17 QRDSFRYFLETGIREELDFFSPIVGQSLGSSSKRPTDRFiSVSFhsKDFYFKKPHYT----------PQEAVQKLGTYKS 86
Cdd:pfam04563    6 QLDSFNEFVDNDLQKIIDENALIESEFEIQHPGENGDKL-SLKF--GQIRLGKPMFDetdgstreiyPQECRLRNLTYSA 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437    87 SLIVPVHvYSKYLNLNATFPVAFC-DLPLMTEH------------------------GTFILNGSPRVIVHQIVR---CP 138
Cdd:pfam04563   83 PLYVDLE-LSVYNGEDIKPIEVFIgRLPIMLRSnacilsgateselvklgecpldpgGYFIINGSEKVIVAQEHRsrnHP 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   139 GVYLKPQFdkqGNRTHLVSFLSAY--------GSWLRF-ETDKKGVVFAHIDNLRK-VPVTVFLQALGFSMDT-IVGALK 207
Cdd:pfam04563  162 IVFKKADP---KKRGSVASVRSSAeisvrpdsTSWVNVlEYLSNGTIYFKFPYIKKeIPIVIILRALGFTSDReIFELIC 238
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   208 YpealdptlKEVDWKLttDEAILLLMSRLFPNRPATVLRGRKFLFNQFFNPRRYSLSDVGRKRVNQKFRMRSKTKHLTLT 287
Cdd:pfam04563  239 Y--------DVNDQQL--QEELLPSLEEGFKIRIQTQEQALDYIGGRGRAIFRMGRPREPRIKYAEEILQKEVLPHLGTY 308
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 113170437   288 PQDA-------LAALDYLLRCENGETEfLDDIDHLKNRRARLAGELIQTQFRLGLNRLERVIYNRI 346
Cdd:pfam04563  309 ELDEtkkayfiGYMIRRLLLLALGRRE-VDDRDHLGNKRLRLAGPLLASLFRVLFKKLVRDVRERL 373
RNA_pol_Rpb2_7 pfam04560
RNA polymerase Rpb2, domain 7; RNA polymerases catalyze the DNA dependent polymerization of ...
1010-1083 1.04e-25

RNA polymerase Rpb2, domain 7; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Rpb2 is the second largest subunit of the RNA polymerase. This domain comprised of the structural domains anchor and clamp. The clamp region (C-terminal) contains a zinc-binding motif. The clamp region is named due to its interaction with the clamp domain found in Rpb1. The domain also contains a region termed "switch 4". The switches within the polymerase are thought to signal different stages of transcription.


Pssm-ID: 461355 [Multi-domain]  Cd Length: 87  Bit Score: 101.51  E-value: 1.04e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  1010 GGQRLGEMEVWALEGFGAAYVLQELLTIKSD----DMIGRNRAFMSM-----IRGTLLPKSG-IPESFKVLVSELRGLCL 1079
Cdd:pfam04560    1 GGLRFGEMERWALIAYGAAHTLQERLTIKSDayevDVCGRCGLYAAYnkcpiCKGETDISPGyIPESFKLLFQELQSLGI 80

                   ....
gi 113170437  1080 DMSI 1083
Cdd:pfam04560   81 DPRL 84
RNA_pol_Rpb2_2 pfam04561
RNA polymerase Rpb2, domain 2; RNA polymerases catalyze the DNA dependent polymerization of ...
136-321 3.68e-24

RNA polymerase Rpb2, domain 2; RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Rpb2 is the second largest subunit of the RNA polymerase. This domain forms one of the two distinctive lobes of the Rpb2 structure. This domain is also known as the lobe domain. DNA has been demonstrated to bind to the concave surface of the lobe domain, and plays a role in maintaining the transcription bubble. Many of the bacterial members contain large insertions within this domain, as region known as dispensable region 1 (DRI).


Pssm-ID: 398318 [Multi-domain]  Cd Length: 185  Bit Score: 100.88  E-value: 3.68e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   136 RCPGVYLKPQFDKQG-NRTHLVSFLSAYGSWLRFETDKKGVVFAHIDNLRKVPVTVFLQALGFSMDT-IVGALKYP---- 209
Cdd:pfam04561    1 RSNGIYVEKELDKNGiIATYTSSLISNRGSWLKLEIDGKTLIWSRPSKKRKIPIVIFLKALGLVSDReILDRLCYDfndp 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437   210 ---EALDPTLKEVDWKLTTDEAILLLMSRLF--PNRPATVLRGRKFLfnQFFNPRRyslsdvgrkRVNQKFRMRSKTKHL 284
Cdd:pfam04561   81 qmlELLKPELEEAENIYTQEEALDYIGKGFAlrRGEEPRLQRAREIL--YSRDPKY---------NLNKHLGLNEPFENE 149
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 113170437   285 TLTPQDALAALDYLLRCENGETEfLDDIDHLKNRRAR 321
Cdd:pfam04561  150 RLKAQDILYMIDRLLNLKLGRRK-PDDIDHLGNKRVR 185
PRK09606 PRK09606
DNA-directed RNA polymerase subunit B''; Validated
119-457 5.08e-23

DNA-directed RNA polymerase subunit B''; Validated


Pssm-ID: 236587 [Multi-domain]  Cd Length: 494  Bit Score: 104.26  E-value: 5.08e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  119 GTFILNGSPRVIVHQIVRCPGVYLKPQFDKQGNRTHLVSFLS---AYGSWLRFETDKKG---VVFAHIDnlRKVPVTVFL 192
Cdd:PRK09606  146 GYFIVNGSERVLMTLEDLAPNKILVEKDERYGDRIEVAKVFSqrrGYRALVTVERNRDGlleVSFPSVP--GSIPFVILM 223
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  193 QALGFSMDT-IVGAL-KYPEALDPTLK-----EVDwklTTDEAILLLMSRLFPNRPATVLRGR-KFLFNQFFNPrrysls 264
Cdd:PRK09606  224 RALGLETDEeIVEAVsDDPEIVKFMLEnleeaEVD---TQEEALEYIGKRVAPGQTKEYRIKRaEYVIDRYLLP------ 294
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  265 dvgrkrvnqkfrmrsktkHLTLTPQDALAALDYLLR-----CE--NGETEfLDDIDHLKNRRARLAGELIQTQFRLGLNR 337
Cdd:PRK09606  295 ------------------HLGVEPEVRRAKAHYLGRmaeacFElaLGRRE-EDDKDHYANKRLKLAGDLMEDLFRVAFNR 355
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 113170437  338 LERVIYNRISDENILRKTPgalgSLNSLIRTQVLASVFQEFF-------GSNQLSQFMDQTNPLAEITHKRRLSSlgPgg 410
Cdd:PRK09606  356 LARDVKYQLERANMRNREL----SIKTAVRSDVLTERLEHAMatgnwvgGRTGVSQLLDRTDYMATLSHLRRVVS--P-- 427
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 113170437  411 LNRDRAGLIVRGIHPSYYGRICPIETPEGKNAGLVGSIATFTQINKN 457
Cdd:PRK09606  428 LSRSQPHFEARDLHPTQWGRICPSETPEGPNCGLVKNFAQMVEISTG 474
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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