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Conserved domains on  [gi|53850624|ref|NP_001005548|]
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RNA polymerase-associated protein LEO1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Leo1 pfam04004
Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The ...
 386-548 5.27e-64

Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The Paf1 complex probably functions during the elongation phase of transcription. The Leo1 subunit of the yeast Paf1-complex binds RNA and contributes to complex recruitment. The subunit acts by co-ordinating co-transcriptional chromain modifications and helping recruitment of mRNA 3prime-end processing factors.


:

Pssm-ID: 461126  Cd Length: 163  Bit Score: 208.97  E-value: 5.27e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   386 YFVKLPNFLSVEPRPFDPQYYEDE-FEDEEMLDEEGRTRLKLKVENTIRWRMRRDeegNEIKESNARIVKWSDGSMSLHL 464
Cdd:pfam04004   1 YLLKVPNFLSIEPKPFDPETFEPEvDEESEVLDEEGRFSIKLTVENTIRWRYSPD---TGIKESNARIVRWSDGSLSLQL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   465 GNEVFDVYKAPLQGDHNHLFIRQGTG--LQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPEC 542
Cdd:pfam04004  78 GDEHFDIQSKPLQDDHTYLAARHESSelLQTQGHITEQLTFRPTSTQSDTHRRLTAALAARHKKTGAKIMLIITTEDPEL 157


                  ....*.
gi 53850624   543 QRTEMI 548
Cdd:pfam04004 158 EKKEAE 163
MSCRAMM_ClfA super family cl41352
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 11-373 5.23e-16

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


The actual alignment was detected with superfamily member NF033609:

Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 82.26  E-value: 5.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   11 EAESEAERKDSDSGSDSDSDQDNGASGSNaSGSESDQDERGDSGQPSNKELFGDDSEEEGAPHHSGSDNHSEQSDNRSEA 90
Cdd:NF033609 553 EIEPIPEDSDSDPGSDSGSDSSNSDSGSD-SGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 631

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   91 SEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKL 170
Cdd:NF033609 632 SDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 711

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  171 QNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEK-GNSDDERPAASDNDEEKQNSDDEDRPQV 249
Cdd:NF033609 712 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSD 791

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  250 SDEEKMQNSDDERPQVSDEDrRHSDDEEEQDQKSESARGSDSEDEvlrmkrknaipSDSEVDSDTEVPKDNNGTMDLFGG 329
Cdd:NF033609 792 SDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSD-----------SDSDSDSDSDSDSDSDSDSDSESD 859

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 53850624  330 AD-DISSGSDGEDKPP-TPGQPVDENGLPQDQQEEEPIPETRIEVE 373
Cdd:NF033609 860 SNsDSESGSNNNVVPPnSPKNGTNASNKNEAKDSKEPLPDTGSEDE 905
 
Name Accession Description Interval E-value
Leo1 pfam04004
Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The ...
 386-548 5.27e-64

Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The Paf1 complex probably functions during the elongation phase of transcription. The Leo1 subunit of the yeast Paf1-complex binds RNA and contributes to complex recruitment. The subunit acts by co-ordinating co-transcriptional chromain modifications and helping recruitment of mRNA 3prime-end processing factors.


Pssm-ID: 461126  Cd Length: 163  Bit Score: 208.97  E-value: 5.27e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   386 YFVKLPNFLSVEPRPFDPQYYEDE-FEDEEMLDEEGRTRLKLKVENTIRWRMRRDeegNEIKESNARIVKWSDGSMSLHL 464
Cdd:pfam04004   1 YLLKVPNFLSIEPKPFDPETFEPEvDEESEVLDEEGRFSIKLTVENTIRWRYSPD---TGIKESNARIVRWSDGSLSLQL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   465 GNEVFDVYKAPLQGDHNHLFIRQGTG--LQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPEC 542
Cdd:pfam04004  78 GDEHFDIQSKPLQDDHTYLAARHESSelLQTQGHITEQLTFRPTSTQSDTHRRLTAALAARHKKTGAKIMLIITTEDPEL 157


                  ....*.
gi 53850624   543 QRTEMI 548
Cdd:pfam04004 158 EKKEAE 163
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 11-373 5.23e-16

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 82.26  E-value: 5.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   11 EAESEAERKDSDSGSDSDSDQDNGASGSNaSGSESDQDERGDSGQPSNKELFGDDSEEEGAPHHSGSDNHSEQSDNRSEA 90
Cdd:NF033609 553 EIEPIPEDSDSDPGSDSGSDSSNSDSGSD-SGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 631

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   91 SEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKL 170
Cdd:NF033609 632 SDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 711

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  171 QNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEK-GNSDDERPAASDNDEEKQNSDDEDRPQV 249
Cdd:NF033609 712 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSD 791

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  250 SDEEKMQNSDDERPQVSDEDrRHSDDEEEQDQKSESARGSDSEDEvlrmkrknaipSDSEVDSDTEVPKDNNGTMDLFGG 329
Cdd:NF033609 792 SDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSD-----------SDSDSDSDSDSDSDSDSDSDSESD 859

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 53850624  330 AD-DISSGSDGEDKPP-TPGQPVDENGLPQDQQEEEPIPETRIEVE 373
Cdd:NF033609 860 SNsDSESGSNNNVVPPnSPKNGTNASNKNEAKDSKEPLPDTGSEDE 905
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 1-263 1.02e-12

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 71.57  E-value: 1.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624      1 MADMEDLFGSEAESEAERKDSDSGSDSDSDQDNGASGSNASGSESDQDERGDSGQPSNKELFG-DDSEEEGAPHHSGSDN 79
Cdd:TIGR00927  627 LGDLSKGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERkGEQEGEGEIEAKEADH 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624     80 HSEQSDNRSEASEERSDHEDNEPSDVD-QHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDD-EKWDG 157
Cdd:TIGR00927  707 KGETEAEEVEHEGETEAEGTEDEGEIEtGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEgEIQAG 786

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624    158 EDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEE 237
Cdd:TIGR00927  787 EDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDGGDSEEE 866

                          250       260
                   ....*....|....*....|....*..
gi 53850624    238 KQNSDD-EDRPQVSDEEKMQNSDDERP 263
Cdd:TIGR00927  867 EEEEEEeEEEEEEEEEEEEEEEENEEP 893
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 32-341 1.26e-09

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 61.46  E-value: 1.26e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   32 DNGASGSNASGSESDQDERGDSGQPSnkelfgDDSEEEGAPHHSGSDnhsEQSDNRSEASEERSDHEDNEPSDVDQHSGS 111
Cdd:NF033609 524 DNEVAFNNGSGSGDGIDKPVVPEQPD------EPGEIEPIPEDSDSD---PGSDSGSDSSNSDSGSDSGSDSTSDSGSDS 594

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  112 EAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSA 191
Cdd:NF033609 595 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 674

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  192 DEEEKMQNTDDEDRAQLSDDDRQQLSEEEkgnSDDERPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDrr 271
Cdd:NF033609 675 DSDSDSDSDSDSDSDSDSDSDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-- 749

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  272 hSDDEEEQDQKSESARGSDSEdevlrmkrknaipSDSEVDSDTEVPKDNNGTMDLFGGADDISSGSDGED 341
Cdd:NF033609 750 -SDSDSDSDSDSDSDSDSDSD-------------SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 805
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 2-269 1.64e-08

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 58.00  E-value: 1.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624    2 ADMEDLFGSEAESEAERKDSDSGSDSDSDQDNGASGSNA-SGSESDQDERGDSGQPSNKELFGDDSEEEGAPHHSGSDNH 80
Cdd:NF033609 596 SDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSdSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 675

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   81 SEQSDNRSEASEERSDHEDNEPSDVDQHSGSEA-HNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGED 159
Cdd:NF033609 676 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 755

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  160 KSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEEKQ 239
Cdd:NF033609 756 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 835

                        250       260       270
                 ....*....|....*....|....*....|
gi 53850624  240 NSDDEDRPQVSDEEKMQNSDDERPQVSDED 269
Cdd:NF033609 836 SDSDSDSDSDSDSDSDSDSDSESDSNSDSE 865
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 10-294 8.46e-08

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 55.69  E-value: 8.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   10 SEAESEAERKDSDSGSDSDSDQDNGASGSN-ASGSESDQDERGDSGQPSNKELFGDDSEEEGAPHHSGSDNHSEQSDNRS 88
Cdd:NF033609 618 SASDSDSASDSDSASDSDSASDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 697

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   89 EASEERSDHEDNEPSDVDQHSGSEAhNDDDDDDDDEDDDDEGHR-SDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDD 167
Cdd:NF033609 698 SDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 776

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  168 EKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEeekgnSDDERPAASDNDEEKQNSDDEDRP 247
Cdd:NF033609 777 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-----SDSDSDSDSDSDSDSDSDSDSDSD 851

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 53850624  248 QVSDEEKMQNSDDER-------PQVSDEDRRHSDDEEEQDQKSESARGSDSEDE 294
Cdd:NF033609 852 SDSDSESDSNSDSESgsnnnvvPPNSPKNGTNASNKNEAKDSKEPLPDTGSEDE 905
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 73-296 2.68e-07

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 53.75  E-value: 2.68e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   73 HHSGSDNHSEQSDNRSEASEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEA----EGSEKA 148
Cdd:PRK12678  58 ARGGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQArerrERGEAA 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  149 QSDDEKWDGEDKSDQS--DDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQ--QLSEEEKGNS 224
Cdd:PRK12678 138 RRGAARKAGEGGEQPAteARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRrdRREQGDRREE 217

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 53850624  225 DDERPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQKSESARGSD----SEDEVL 296
Cdd:PRK12678 218 RGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDRRGRRGGDGGNERepelREDDVL 293
BMS1 COG5192
GTP-binding protein required for 40S ribosome biogenesis [Translation, ribosomal structure and ...
 45-294 6.31e-05

GTP-binding protein required for 40S ribosome biogenesis [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227519 [Multi-domain]  Cd Length: 1077  Bit Score: 46.27  E-value: 6.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   45 SDQDERGDSGQPSNKElfgDDSEEEGAPHHSGSDNHSEQSDNRSEASEERSDHEDNEpsdvDQHSGSEAHNDDDDDDDDE 124
Cdd:COG5192  423 SREDELSFDDSDVSTS---DENEDVDFTGKKGAINNEDESDNEEVAFDSDSQFDESE----GNLRWKEGLASKLAYSQSG 495

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  125 DDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEE--EKMQNTDD 202
Cdd:COG5192  496 KRGRNIQKIFYDESLSPEECIEEYKGESAKSSESDLVVQDEPEDFFDVSKVANESISSNHEKLMESEFEElkKKWSSLAQ 575

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  203 EDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEEKQNSDDEdrpqvsDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQK 282
Cdd:COG5192  576 LKSRFQKDATLDSIEGEEELIQDDEKGNFEDLEDEENSSDNE------MEESRGSSVTAENEESADEVDYETEREENARK 649

                        250
                 ....*....|..
gi 53850624  283 SESARGSDSEDE 294
Cdd:COG5192  650 KEELRGNFELEE 661
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 141-256 7.27e-05

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 46.08  E-value: 7.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   141 EAEGSEKAQSDDEKWDGEDKSDQSDDDEklqnSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLsdddRQQLsEEE 220
Cdd:pfam04931 624 DARENPEGQQELFEDEDEDEEDDDEEED----DDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDEL----RAKL-AEA 694

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 53850624   221 KGNSDDerpaASDNDEEkqnSDDEDrpqVSDEEKMQ 256
Cdd:pfam04931 695 LGEHGD----DADDDDS---DSDED---MDDEQMMA 720
 
Name Accession Description Interval E-value
Leo1 pfam04004
Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The ...
 386-548 5.27e-64

Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The Paf1 complex probably functions during the elongation phase of transcription. The Leo1 subunit of the yeast Paf1-complex binds RNA and contributes to complex recruitment. The subunit acts by co-ordinating co-transcriptional chromain modifications and helping recruitment of mRNA 3prime-end processing factors.


Pssm-ID: 461126  Cd Length: 163  Bit Score: 208.97  E-value: 5.27e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   386 YFVKLPNFLSVEPRPFDPQYYEDE-FEDEEMLDEEGRTRLKLKVENTIRWRMRRDeegNEIKESNARIVKWSDGSMSLHL 464
Cdd:pfam04004   1 YLLKVPNFLSIEPKPFDPETFEPEvDEESEVLDEEGRFSIKLTVENTIRWRYSPD---TGIKESNARIVRWSDGSLSLQL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   465 GNEVFDVYKAPLQGDHNHLFIRQGTG--LQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPEC 542
Cdd:pfam04004  78 GDEHFDIQSKPLQDDHTYLAARHESSelLQTQGHITEQLTFRPTSTQSDTHRRLTAALAARHKKTGAKIMLIITTEDPEL 157


                  ....*.
gi 53850624   543 QRTEMI 548
Cdd:pfam04004 158 EKKEAE 163
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 11-373 5.23e-16

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 82.26  E-value: 5.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   11 EAESEAERKDSDSGSDSDSDQDNGASGSNaSGSESDQDERGDSGQPSNKELFGDDSEEEGAPHHSGSDNHSEQSDNRSEA 90
Cdd:NF033609 553 EIEPIPEDSDSDPGSDSGSDSSNSDSGSD-SGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 631

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   91 SEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKL 170
Cdd:NF033609 632 SDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 711

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  171 QNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEK-GNSDDERPAASDNDEEKQNSDDEDRPQV 249
Cdd:NF033609 712 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSD 791

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  250 SDEEKMQNSDDERPQVSDEDrRHSDDEEEQDQKSESARGSDSEDEvlrmkrknaipSDSEVDSDTEVPKDNNGTMDLFGG 329
Cdd:NF033609 792 SDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSD-----------SDSDSDSDSDSDSDSDSDSDSESD 859

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 53850624  330 AD-DISSGSDGEDKPP-TPGQPVDENGLPQDQQEEEPIPETRIEVE 373
Cdd:NF033609 860 SNsDSESGSNNNVVPPnSPKNGTNASNKNEAKDSKEPLPDTGSEDE 905
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 1-263 1.02e-12

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 71.57  E-value: 1.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624      1 MADMEDLFGSEAESEAERKDSDSGSDSDSDQDNGASGSNASGSESDQDERGDSGQPSNKELFG-DDSEEEGAPHHSGSDN 79
Cdd:TIGR00927  627 LGDLSKGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERkGEQEGEGEIEAKEADH 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624     80 HSEQSDNRSEASEERSDHEDNEPSDVD-QHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDD-EKWDG 157
Cdd:TIGR00927  707 KGETEAEEVEHEGETEAEGTEDEGEIEtGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEgEIQAG 786

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624    158 EDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEE 237
Cdd:TIGR00927  787 EDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDGGDSEEE 866

                          250       260
                   ....*....|....*....|....*..
gi 53850624    238 KQNSDD-EDRPQVSDEEKMQNSDDERP 263
Cdd:TIGR00927  867 EEEEEEeEEEEEEEEEEEEEEEENEEP 893
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 50-294 5.08e-10

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 63.09  E-value: 5.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624     50 RGDSGQPSNKelfGDDSEEEGAPHHSGSDNHSEQSDNRSEASEERSDHEDNEpSDVDQHSGSEAHNDDDDDDDDEDDDDE 129
Cdd:TIGR00927  632 KGDVAEAEHT---GERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENE-SEGEIPAERKGEQEGEGEIEAKEADHK 707

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624    130 GHRSDEGSHH---SEAEGSEKAQSDDEKWDGEDKSDQSDDDekLQNSDDEEREqgSDDEKLQNSADEEEKMQNTDDEDRA 206
Cdd:TIGR00927  708 GETEAEEVEHegeTEAEGTEDEGEIETGEEGEEVEDEGEGE--AEGKHEVETE--GDRKETEHEGETEAEGKEDEDEGEI 783

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624    207 QLSDDDRQQLSEEE--KGNSDDERPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRHSDDEEEQDqkse 284
Cdd:TIGR00927  784 QAGEDGEMKGDEGAegKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSD---- 859

                          250
                   ....*....|
gi 53850624    285 sarGSDSEDE 294
Cdd:TIGR00927  860 ---GGDSEEE 866
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 32-341 1.26e-09

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 61.46  E-value: 1.26e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   32 DNGASGSNASGSESDQDERGDSGQPSnkelfgDDSEEEGAPHHSGSDnhsEQSDNRSEASEERSDHEDNEPSDVDQHSGS 111
Cdd:NF033609 524 DNEVAFNNGSGSGDGIDKPVVPEQPD------EPGEIEPIPEDSDSD---PGSDSGSDSSNSDSGSDSGSDSTSDSGSDS 594

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  112 EAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSA 191
Cdd:NF033609 595 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 674

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  192 DEEEKMQNTDDEDRAQLSDDDRQQLSEEEkgnSDDERPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDrr 271
Cdd:NF033609 675 DSDSDSDSDSDSDSDSDSDSDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-- 749

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  272 hSDDEEEQDQKSESARGSDSEdevlrmkrknaipSDSEVDSDTEVPKDNNGTMDLFGGADDISSGSDGED 341
Cdd:NF033609 750 -SDSDSDSDSDSDSDSDSDSD-------------SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 805
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 2-269 1.64e-08

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 58.00  E-value: 1.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624    2 ADMEDLFGSEAESEAERKDSDSGSDSDSDQDNGASGSNA-SGSESDQDERGDSGQPSNKELFGDDSEEEGAPHHSGSDNH 80
Cdd:NF033609 596 SDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSdSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 675

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   81 SEQSDNRSEASEERSDHEDNEPSDVDQHSGSEA-HNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGED 159
Cdd:NF033609 676 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 755

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  160 KSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEEKQ 239
Cdd:NF033609 756 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 835

                        250       260       270
                 ....*....|....*....|....*....|
gi 53850624  240 NSDDEDRPQVSDEEKMQNSDDERPQVSDED 269
Cdd:NF033609 836 SDSDSDSDSDSDSDSDSDSDSESDSNSDSE 865
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 10-294 8.46e-08

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 55.69  E-value: 8.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   10 SEAESEAERKDSDSGSDSDSDQDNGASGSN-ASGSESDQDERGDSGQPSNKELFGDDSEEEGAPHHSGSDNHSEQSDNRS 88
Cdd:NF033609 618 SASDSDSASDSDSASDSDSASDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 697

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   89 EASEERSDHEDNEPSDVDQHSGSEAhNDDDDDDDDEDDDDEGHR-SDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDD 167
Cdd:NF033609 698 SDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 776

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  168 EKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEeekgnSDDERPAASDNDEEKQNSDDEDRP 247
Cdd:NF033609 777 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-----SDSDSDSDSDSDSDSDSDSDSDSD 851

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 53850624  248 QVSDEEKMQNSDDER-------PQVSDEDRRHSDDEEEQDQKSESARGSDSEDE 294
Cdd:NF033609 852 SDSDSESDSNSDSESgsnnnvvPPNSPKNGTNASNKNEAKDSKEPLPDTGSEDE 905
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 83-376 1.17e-07

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 55.39  E-value: 1.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624     83 QSDNRSEASEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDdeddddeGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSD 162
Cdd:TIGR00927  637 EAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETK-------GENESEGEIPAERKGEQEGEGEIEAKEADHKGE 709

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624    163 QsdDDEKLQNSDDEEREQGSDDEKLQNSADEEEKmqntDDEDRAQLSdddrqqlSEEEKGNSDDERPAASDNDEEKQNSD 242
Cdd:TIGR00927  710 T--EAEEVEHEGETEAEGTEDEGEIETGEEGEEV----EDEGEGEAE-------GKHEVETEGDRKETEHEGETEAEGKE 776

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624    243 DEDRPQVSDEE--KMQNSDDERPQVSDEDRRHSDDEEE-QDQKSESARGSDSEDEVLRmkrknaipSDSEVDSDTEVPKD 319
Cdd:TIGR00927  777 DEDEGEIQAGEdgEMKGDEGAEGKVEHEGETEAGEKDEhEGQSETQADDTEVKDETGE--------QELNAENQGEAKQD 848

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 53850624    320 NNGtMDLFGGADdissGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPK 376
Cdd:TIGR00927  849 EKG-VDGGGGSD----GGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPE 900
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 11-197 2.34e-07

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 54.23  E-value: 2.34e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624     11 EAESEAERKDSDSGSDSDSDQDNGASGSNASGSESDQDERGDSGQPSNKELFGDDSEEEgapHHSGSDNHSEQSDNRSEA 90
Cdd:TIGR00927  707 KGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETE---HEGETEAEGKEDEDEGEI 783

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624     91 -SEERSDHEDNEPSDVDQHSGSEAH---NDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDD 166
Cdd:TIGR00927  784 qAGEDGEMKGDEGAEGKVEHEGETEageKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDGGDS 863

                          170       180       190
                   ....*....|....*....|....*....|.
gi 53850624    167 DEKLQNSDDEEREQGSDDEKLQNSADEEEKM 197
Cdd:TIGR00927  864 EEEEEEEEEEEEEEEEEEEEEEEEEENEEPL 894
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 73-296 2.68e-07

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 53.75  E-value: 2.68e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   73 HHSGSDNHSEQSDNRSEASEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEA----EGSEKA 148
Cdd:PRK12678  58 ARGGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQArerrERGEAA 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  149 QSDDEKWDGEDKSDQS--DDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQ--QLSEEEKGNS 224
Cdd:PRK12678 138 RRGAARKAGEGGEQPAteARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRrdRREQGDRREE 217

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 53850624  225 DDERPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQKSESARGSD----SEDEVL 296
Cdd:PRK12678 218 RGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDRRGRRGGDGGNERepelREDDVL 293
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 33-269 3.96e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 46.82  E-value: 3.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   33 NGASGSNASGSESDQDERGDSGQPSNKELFGDDSEEEGAPHHSGSDNHSEQSDN-RSEASEERSDHEDNEPSDVDQHSGS 111
Cdd:PRK12678  60 GGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAaAAEAASAPEAAQARERRERGEAARR 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  112 EAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSDDEklqnsa 191
Cdd:PRK12678 140 GAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGD------ 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  192 deeekmQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEEKQNSDDEDRPQVSD--EEKMQNSDDER----PQV 265
Cdd:PRK12678 214 ------RREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRdrDRRGRRGGDGGnerePEL 287


                 ....
gi 53850624  266 SDED 269
Cdd:PRK12678 288 REDD 291
BMS1 COG5192
GTP-binding protein required for 40S ribosome biogenesis [Translation, ribosomal structure and ...
 45-294 6.31e-05

GTP-binding protein required for 40S ribosome biogenesis [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227519 [Multi-domain]  Cd Length: 1077  Bit Score: 46.27  E-value: 6.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   45 SDQDERGDSGQPSNKElfgDDSEEEGAPHHSGSDNHSEQSDNRSEASEERSDHEDNEpsdvDQHSGSEAHNDDDDDDDDE 124
Cdd:COG5192  423 SREDELSFDDSDVSTS---DENEDVDFTGKKGAINNEDESDNEEVAFDSDSQFDESE----GNLRWKEGLASKLAYSQSG 495

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  125 DDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEE--EKMQNTDD 202
Cdd:COG5192  496 KRGRNIQKIFYDESLSPEECIEEYKGESAKSSESDLVVQDEPEDFFDVSKVANESISSNHEKLMESEFEElkKKWSSLAQ 575

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  203 EDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEEKQNSDDEdrpqvsDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQK 282
Cdd:COG5192  576 LKSRFQKDATLDSIEGEEELIQDDEKGNFEDLEDEENSSDNE------MEESRGSSVTAENEESADEVDYETEREENARK 649

                        250
                 ....*....|..
gi 53850624  283 SESARGSDSEDE 294
Cdd:COG5192  650 KEELRGNFELEE 661
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 141-256 7.27e-05

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 46.08  E-value: 7.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   141 EAEGSEKAQSDDEKWDGEDKSDQSDDDEklqnSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLsdddRQQLsEEE 220
Cdd:pfam04931 624 DARENPEGQQELFEDEDEDEEDDDEEED----DDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDEL----RAKL-AEA 694

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 53850624   221 KGNSDDerpaASDNDEEkqnSDDEDrpqVSDEEKMQ 256
Cdd:pfam04931 695 LGEHGD----DADDDDS---DSDED---MDDEQMMA 720
PRK08581 PRK08581
amidase domain-containing protein;
32-294 7.78e-05

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 45.93  E-value: 7.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   32 DNGASGSNASGSESDQDERGDSGQPSNKELFGDDSEeegaphhsgSDNHSEQSDNRSEASEERSDHEDNEPSD--VDQHS 109
Cdd:PRK08581  30 PQKDSTAKTTSHDSKKSNDDETSKDTSSKDTDKADN---------NNTSNQDNNDKKFSTIDSSTSDSNNIIDfiYKNLP 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  110 GSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEkwDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQN 189
Cdd:PRK08581 101 QTNINQLLTKNKYDDNYSLTTLIQNLFNLNSDISDYEQPRNSEK--STNDSNKNSDSSIKNDTDTQSSKQDKADNQKAPS 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  190 SADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDerpaasDNDEEKQNSDDEDRPQVSDEekmqNSDDERPQVSDED 269
Cdd:PRK08581 179 SNNTKPSTSNKQPNSPKPTQPNQSNSQPASDDTANQK------SSSKDNQSMSDSALDSILDQ----YSEDAKKTQKDYA 248

                        250       260
                 ....*....|....*....|....*
gi 53850624  270 RRHSDDEEEQDQKSESARGSDSEDE 294
Cdd:PRK08581 249 SQSKKDKTETSNTKNPQLPTQDELK 273
PHA03169 PHA03169
hypothetical protein; Provisional
 132-306 1.21e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 44.96  E-value: 1.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  132 RSDEGSHHSEAEGSEKAQSDDEKwDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDraqlSDD 211
Cdd:PHA03169  78 ESRHGEKEERGQGGPSGSGSESV-GSPTPSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEP----APP 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  212 DRQQLSEEEKGNSDDErPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVS--DEDRRHSDDEEEQDQKSESARGS 289
Cdd:PHA03169 153 ESHNPSPNQQPSSFLQ-PSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSppDEPGEPQSPTPQQAPSPNTQQAV 231

                        170
                 ....*....|....*..
gi 53850624  290 DSEDEVLRMKRKNAIPS 306
Cdd:PHA03169 232 EHEDEPTEPEREGPPFP 248
PTZ00482 PTZ00482
membrane-attack complex/perforin (MACPF) Superfamily; Provisional
 138-290 1.96e-04

membrane-attack complex/perforin (MACPF) Superfamily; Provisional


Pssm-ID: 240433 [Multi-domain]  Cd Length: 844  Bit Score: 44.86  E-value: 1.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  138 HHSEAEGSEKAQSDDEK-----W-DGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDD 211
Cdd:PTZ00482  76 HASFLNQRKSLDDDDDDefdflYeDDEDDAGNATSGESSTDDDSLLELPDRDEDADTQANNDQTNDFDQDDSSNSQTDQG 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  212 DRQ--QLSEEEKGNSDDERPaaSDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQKSESARGS 289
Cdd:PTZ00482 156 LKQsvNLSSAEKLIEEKKGQ--TENTFKFYNFGNDGEEAAAKDGGKSKSSDPGPLNDSDGQGDDGDPESAEEDKAASNTR 233


                 .
gi 53850624  290 D 290
Cdd:PTZ00482 234 A 234
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 141-244 2.03e-04

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 44.40  E-value: 2.03e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624 141 EAEGSEKAQSDDEkwDGEDKSDQSDDDEklqnSDDEEREQGSDDEklqnSADEEEKMQNTDDEDRAQLSDDDRQQLSEEE 220
Cdd:COG4547 209 EELGEDEDEEDED--DEDDSGEQEEDEE----DGEDEDEESDEGA----EAEDAEASGDDAEEGESEAAEAESDEMAEEA 278

                        90       100
                ....*....|....*....|....
gi 53850624 221 KGNSDDERPAASDNDEEKQNSDDE 244
Cdd:COG4547 279 EGEDSEEPGEPWRPNAPPPDDPAD 302
Nop14 pfam04147
Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the ...
 174-313 4.48e-04

Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.


Pssm-ID: 461196  Cd Length: 835  Bit Score: 43.38  E-value: 4.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   174 DDEEREQGSDDEKLQNSADEEEkmqntDDEDRAQLSDDDRQQLSEEEKGnsDDERPAASDNDEEKQNSDDEDRPQVSDEE 253
Cdd:pfam04147 281 EEDEEEEDGKKKKKHKSADDLD-----DDFVVDDDDDDEEFGLGKGIKE--RPTATELGDEDEDDFIIDDDLVESESDLE 353

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   254 KMQNSDDERpQVSDEDRRHSDDEEEQDQKSESARGSDSEDEVLRMKRKNAIPSDSEVDSD 313
Cdd:pfam04147 354 LDEEEEDEE-EEDDEDEDEEEEEDDDDLSDLESEEDEEDDEFEEEKKKKKKKDEEGAKEE 412
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 140-322 5.23e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 43.35  E-value: 5.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  140 SEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEE 219
Cdd:PRK12678  87 ARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGAARKAGEGGEQPATEARADAAERTEE 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  220 EKgnsdderpaasdNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRhsDDEEEQDQKSESARGSDSEDEVLRMK 299
Cdd:PRK12678 167 EE------------RDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRR--DRREQGDRREERGRRDGGDRRGRRRR 232

                        170       180
                 ....*....|....*....|...
gi 53850624  300 RKNAIPSDSEVDSDTEVPKDNNG 322
Cdd:PRK12678 233 RDRRDARGDDNREDRGDRDGDDG 255
PHA02664 PHA02664
hypothetical protein; Provisional
 33-183 1.03e-03

hypothetical protein; Provisional


Pssm-ID: 177447  Cd Length: 534  Bit Score: 42.30  E-value: 1.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   33 NGASGSNASGSESDQDERGDSGQpsnkelfgDDSEEEGAPHHSGSDNHSEQSDNRSEASEERSDHEDNepsdvdqhsgse 112
Cdd:PHA02664 413 RAAAAAAAANAPADQDVEAEAHD--------EFDQDPGAPAHADRADSDEDDMDEQESGDERADGEDD------------ 472

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 53850624  113 ahnddddddddeddddeghrSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSD 183
Cdd:PHA02664 473 --------------------SDSSYSYSTTSSEDESDSADDSWGDESDSGIEHDDGGVGQAIEEEEEEERA 523
PTZ00482 PTZ00482
membrane-attack complex/perforin (MACPF) Superfamily; Provisional
 162-316 2.26e-03

membrane-attack complex/perforin (MACPF) Superfamily; Provisional


Pssm-ID: 240433 [Multi-domain]  Cd Length: 844  Bit Score: 41.39  E-value: 2.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  162 DQSDDDE--KLQNSDDEEREQGSDDEklqnSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSD----DERPAASDND 235
Cdd:PTZ00482  87 DDDDDDEfdFLYEDDEDDAGNATSGE----SSTDDDSLLELPDRDEDADTQANNDQTNDFDQDDSSnsqtDQGLKQSVNL 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  236 EEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQKSESARGSDSEDEVLRmKRKNAIPSDSEVDSDTE 315
Cdd:PTZ00482 163 SSAEKLIEEKKGQTENTFKFYNFGNDGEEAAAKDGGKSKSSDPGPLNDSDGQGDDGDPESAE-EDKAASNTRAAYTKATS 241


                 .
gi 53850624  316 V 316
Cdd:PTZ00482 242 V 242
PHA03169 PHA03169
hypothetical protein; Provisional
 63-253 2.87e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 40.72  E-value: 2.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   63 GDDSEEEGAPHHSGSDNHSEQSDNRSEASEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEA 142
Cdd:PHA03169  48 PPAPTTSGPQVRAVAEQGHRQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASGLSPENTSGSS 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  143 EGSEKAQSDDEKwDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKG 222
Cdd:PHA03169 128 PESPASHSPPPS-PPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQS 206

                        170       180       190
                 ....*....|....*....|....*....|.
gi 53850624  223 NSDDERPAASDNDEEKQNSDDEDRPQVSDEE 253
Cdd:PHA03169 207 PPDEPGEPQSPTPQQAPSPNTQQAVEHEDEP 237
COG5177 COG5177
Uncharacterized conserved protein [Function unknown];
140-315 3.46e-03

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227504 [Multi-domain]  Cd Length: 769  Bit Score: 40.83  E-value: 3.46e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624 140 SEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQ-QLSE 218
Cdd:COG5177 301 GQYEQTIREIFADRATKLELDLQTVFESNMNRDTLDEYAPEGEDLRSDYDEDFEYDGLTTVRIDDHGFLPGREQTsKKAA 380

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624 219 EEKGNSDDERPAASDNDEEKQNSDDEdrpqvsdEEKMQNSDDERPQVSDEDRRHSDDEEEQDQKSESARGSDSEDEVLRM 298
Cdd:COG5177 381 VPKGTSFYQAKWAEDEEEEDGQCNDE-------ESTMSAIDDDDPKENDNEEVAGDEESAIDDNEGFEELSPEEEERQLR 453

                       170
                ....*....|....*..
gi 53850624 299 KRKNAIPSDSEVDSDTE 315
Cdd:COG5177 454 EFRDMEKEDREFPDEAE 470
PTZ00482 PTZ00482
membrane-attack complex/perforin (MACPF) Superfamily; Provisional
 159-363 4.32e-03

membrane-attack complex/perforin (MACPF) Superfamily; Provisional


Pssm-ID: 240433 [Multi-domain]  Cd Length: 844  Bit Score: 40.23  E-value: 4.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  159 DKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEekgnSDDERPAASDNDEEK 238
Cdd:PTZ00482  37 TVEDIEGPSAVDERTSGVLRDEGKHANILYNSILCNQKKHASFLNQRKSLDDDDDDEFDFL----YEDDEDDAGNATSGE 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  239 QNSDDEDRPQVSDEEKMQNSDDERPQVSDEDrrhsDDEEEQDQKSESARGSDSedevlrmkrknaIPSDSEVDSDTEVPK 318
Cdd:PTZ00482 113 SSTDDDSLLELPDRDEDADTQANNDQTNDFD----QDDSSNSQTDQGLKQSVN------------LSSAEKLIEEKKGQT 176

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 53850624  319 DNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEE 363
Cdd:PTZ00482 177 ENTFKFYNFGNDGEEAAAKDGGKSKSSDPGPLNDSDGQGDDGDPE 221
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 159-245 4.32e-03

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 40.16  E-value: 4.32e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624 159 DKSDQSDDDEklQNSDDEEREQGSDDEKLQNSADEEEkmqntDDEDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEEK 238
Cdd:COG4547 206 DLAEELGEDE--DEEDEDDEDDSGEQEEDEEDGEDED-----EESDEGAEAEDAEASGDDAEEGESEAAEAESDEMAEEA 278


                ....*..
gi 53850624 239 QNSDDED 245
Cdd:COG4547 279 EGEDSEE 285
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 201-313 4.71e-03

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 40.16  E-value: 4.71e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624 201 DDEDR-AQLSdddRQQLSEEEKGNSDDERPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRHSDD---- 275
Cdd:COG4547 189 DDQAAfARAV---RDLLRDLDLAEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDEGAEAEDAEASGDDAEEgese 265

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 53850624 276 --EEEQDQKSESARGSDSEDEVLrMKRKNAIPSDSEVDSD 313
Cdd:COG4547 266 aaEAESDEMAEEAEGEDSEEPGE-PWRPNAPPPDDPADPD 304
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 151-317 5.05e-03

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 40.15  E-value: 5.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   151 DDEKWDGEDKSDQSDDdeklQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLS-----EEEKGNSD 225
Cdd:PTZ00341  418 DLEKQKYMDMLDGSED----ESVEDNEEEHSGDANEEELSVDEHVEEHNADDSGEQQSDDESGEHQSvneivEEQSVNEH 493

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   226 DERPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDD--ERPQVsdedrrhsddEEEQDQKSESARGSDSEDEVlrmkrkNA 303
Cdd:PTZ00341  494 VEEPTVADIVEQETVDEHVEEPAVDENEEQQTADEhvEEPTI----------AEEHVEEEISTAEEHIEEPA------SD 557

                         170
                  ....*....|....
gi 53850624   304 IPSDSEVDSDTEVP 317
Cdd:PTZ00341  558 VQQDSEAAPTIEIP 571
PHA03169 PHA03169
hypothetical protein; Provisional
 63-247 5.46e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 39.57  E-value: 5.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   63 GDDSEEEGAPHHSGSDNHSEQSDNRSeaSEERSDHEDNEPSDVDQHSGSEAhndddDDDDDEDDDDEGHRSDEGSHHSEA 142
Cdd:PHA03169  70 ESDTETAEESRHGEKEERGQGGPSGS--GSESVGSPTPSPSGSAEELASGL-----SPENTSGSSPESPASHSPPPSPPS 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624  143 EGSEKAQSDDEKwDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEE-EK 221
Cdd:PHA03169 143 HPGPHEPAPPES-HNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTpQQ 221

                        170       180
                 ....*....|....*....|....*.
gi 53850624  222 GNSDDERPAASDNDEEKQNSDDEDRP 247
Cdd:PHA03169 222 APSPNTQQAVEHEDEPTEPEREGPPF 247
Nop14 pfam04147
Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the ...
 146-240 6.66e-03

Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.


Pssm-ID: 461196  Cd Length: 835  Bit Score: 39.91  E-value: 6.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624   146 EKAQSDDEKWDGEDkSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEkmqntDDEDRAQLSDDDRQQLSEEEKGNSD 225
Cdd:pfam04147 324 ERPTATELGDEDED-DFIIDDDLVESESDLELDEEEEDEEEEDDEDEDEE-----EEEDDDDLSDLESEEDEEDDEFEEE 397

                          90
                  ....*....|....*
gi 53850624   226 DERPAASDNDEEKQN 240
Cdd:pfam04147 398 KKKKKKKDEEGAKEE 412
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 170-269 8.15e-03

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 39.39  E-value: 8.15e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624 170 LQNSDDEEREQGSDDEklqNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEEKQNSDDEDRPQV 249
Cdd:COG4547 205 LDLAEELGEDEDEEDE---DDEDDSGEQEEDEEDGEDEDEESDEGAEAEDAEASGDDAEEGESEAAEAESDEMAEEAEGE 281

                        90       100
                ....*....|....*....|
gi 53850624 250 SDEEKMQNSDDERPQVSDED 269
Cdd:COG4547 282 DSEEPGEPWRPNAPPPDDPA 301
COG5593 COG5593
Nucleic-acid-binding protein possibly involved in ribosomal biogenesis [Translation, ribosomal ...
 152-306 9.08e-03

Nucleic-acid-binding protein possibly involved in ribosomal biogenesis [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227880 [Multi-domain]  Cd Length: 821  Bit Score: 39.25  E-value: 9.08e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53850624 152 DEKWDGEDKSDQSDDDEklqnSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEeekgnSDDERPAA 231
Cdd:COG5593 668 DGKGKKSNKASFDSDDE----MDENEIWSALVKSRPDVEDDSDDSELDFAEDDFSDSTSDDEPKLDA-----IDDEDAKS 738

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 53850624 232 sdndEEKQNSDDEDRPQ--VSDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQKSESARGSDsedevlRMKRKNAIPS 306
Cdd:COG5593 739 ----EGSQESDQEEGLDeiFYSFDGEQDNSDSFAESSEEDESSEEEKEEEENKEVSAKRAK------KKQRKNMLKS 805
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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