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Conserved domains on  [gi|56090427|ref|NP_001007695|]
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interferon-induced protein with tetratricopeptide repeats 3 [Rattus norvegicus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 12138577)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
96-325 1.66e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.81  E-value: 1.66e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  96 TWGNYAWIYYRIGQLSEAQAYADKVRQVCQKFANPYSMEcpeldceeGWTRLKCGRNERAKMCFEKALEEKPEDPECRAG 175
Cdd:COG0457  10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNL--------GLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 176 MAIAMYRLQEKPEkqfSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKG 255
Cdd:COG0457  82 LGLALQALGRYEE---ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 256 NLDRAIEFLGKALRSTANNSPLYSLVMCRYREKLKQLQNTGEADKSERRQTMEELRRLTMEYMNKALQRR 325
Cdd:COG0457 159 RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALA 228
TPR_12 pfam13424
Tetratricopeptide repeat;
51-126 9.37e-04

Tetratricopeptide repeat;


:

Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 9.37e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56090427    51 ATMYDLLAYIKHLDGENEAALECLGQAEDLRKSERSDRAEIKcLVTWGNYAWIYYRIGQLSEAQAYADKVRQVCQK 126
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLT-ATTLLNLGRLYLELGRYEEALELLERALALAEK 77
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
96-325 1.66e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.81  E-value: 1.66e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  96 TWGNYAWIYYRIGQLSEAQAYADKVRQVCQKFANPYSMEcpeldceeGWTRLKCGRNERAKMCFEKALEEKPEDPECRAG 175
Cdd:COG0457  10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNL--------GLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 176 MAIAMYRLQEKPEkqfSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKG 255
Cdd:COG0457  82 LGLALQALGRYEE---ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 256 NLDRAIEFLGKALRSTANNSPLYSLVMCRYREKLKQLQNTGEADKSERRQTMEELRRLTMEYMNKALQRR 325
Cdd:COG0457 159 RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALA 228
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 56-278 6.57e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.62  E-value: 6.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427    56 LLAYIKHLDGENEAALECLGQAEDLRKSERSDRAeikclvtwgNYAWIYYRIGQLSEAQAYADKVRQvcqKFANPysmec 135
Cdd:TIGR02917 198 LKGDLLLSLGNIELALAAYRKAIALRPNNIAVLL---------ALATILIEAGEFEEAEKHADALLK---KAPNS----- 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   136 PELDCEEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQ--EKPEKQFSvDALKQAMElnsqNQYEKVLL 213
Cdd:TIGR02917 261 PLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGnlEQAYQYLN-QILKYAPN----SHQARRLL 335

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56090427   214 ALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLY 278
Cdd:TIGR02917 336 ASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAAR 400
TPR_19 pfam14559
Tetratricopeptide repeat;
221-281 5.16e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.95  E-value: 5.16e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56090427   221 GEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLYSLV 281
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALL 62
TPR_12 pfam13424
Tetratricopeptide repeat;
51-126 9.37e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 9.37e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56090427    51 ATMYDLLAYIKHLDGENEAALECLGQAEDLRKSERSDRAEIKcLVTWGNYAWIYYRIGQLSEAQAYADKVRQVCQK 126
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLT-ATTLLNLGRLYLELGRYEEALELLERALALAEK 77
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
96-325 1.66e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.81  E-value: 1.66e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  96 TWGNYAWIYYRIGQLSEAQAYADKVRQVCQKFANPYSMEcpeldceeGWTRLKCGRNERAKMCFEKALEEKPEDPECRAG 175
Cdd:COG0457  10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNL--------GLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 176 MAIAMYRLQEKPEkqfSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKG 255
Cdd:COG0457  82 LGLALQALGRYEE---ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 256 NLDRAIEFLGKALRSTANNSPLYSLVMCRYREKLKQLQNTGEADKSERRQTMEELRRLTMEYMNKALQRR 325
Cdd:COG0457 159 RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALA 228
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 154-280 7.95e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 65.03  E-value: 7.95e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 154 RAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEkqfSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDA 233
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDE---ALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERA 77

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 56090427 234 LEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLYSL 280
Cdd:COG4235  78 LALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLL 124
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 147-386 8.90e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.22  E-value: 8.90e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 147 LKCGRNERAKMCFEKALEEKPEDPECRAGMAiAMYRLQEKPEKqfSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEA 226
Cdd:COG2956  19 LLNGQPDKAIDLLEEALELDPETVEAHLALG-NLYRRRGEYDR--AIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRA 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 227 ERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLYslvmCRYREKLKQLQNTGEAdkserrqt 306
Cdd:COG2956  96 EELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAY----CELAELYLEQGDYDEA-------- 163

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 307 meelrrltMEYMNKALQRRPSPLNSYSDLI-------DFPEVEKCYQMVFSEESPRAEDQELFERYcnLQEYHRKSEGLK 379
Cdd:COG2956 164 --------IEALEKALKLDPDCARALLLLAelyleqgDYEEAIAALERALEQDPDYLPALPRLAEL--YEKLGDPEEALE 233


                ....*..
gi 56090427 380 ALKDLMQ 386
Cdd:COG2956 234 LLRKALE 240
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
51-269 2.81e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 66.18  E-value: 2.81e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  51 ATMYDLLAYIKHLDGENEAALECLGQAEDLRKSErsdraeikcLVTWGNYAWIYYRIGQLSEAQAYADKVRQVCQKFANP 130
Cdd:COG0457   8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDD---------AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 131 YSMecpeldceEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEkqfSVDALKQAMELNSQNQYEK 210
Cdd:COG0457  79 LNN--------LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE---AIEAYERALELDPDDADAL 147

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 56090427 211 VLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALR 269
Cdd:COG0457 148 YNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 41-281 1.65e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 64.37  E-value: 1.65e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  41 QIENLNSEHKATMYdLLAYIKHLDGENEAALECLGQAEDLRKSERSDRAEIkclvtwgnyAWIYYRIGQLSEAQAYADKV 120
Cdd:COG2956  33 EALELDPETVEAHL-ALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLEL---------AQDYLKAGLLDRAEELLEKL 102

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 121 RQVcqkfaNPYSMECPELDCEegwTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAmYRLQEKPEKqfSVDALKQAM 200
Cdd:COG2956 103 LEL-----DPDDAEALRLLAE---IYEQEGDWEKAIEVLERLLKLGPENAHAYCELAEL-YLEQGDYDE--AIEALEKAL 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 201 ELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLYSL 280
Cdd:COG2956 172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLAL 251


                .
gi 56090427 281 V 281
Cdd:COG2956 252 A 252
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 134-274 1.00e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.44  E-value: 1.00e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 134 ECPELDCEEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEkqfSVDALKQAMELNSQNQYEKVLL 213
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDE---AIVLLHEALELDPDEPEARLNL 78

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56090427 214 ALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANN 274
Cdd:COG4783  79 GLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 54-294 1.07e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.47  E-value: 1.07e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  54 YDLLAYIKHLDGENEAALECLGQAEDLRKSERSDRAEIKCLVTWgnYAWIYYRIGQLSEAQAYADKVRQvcqkfANPysm 133
Cdd:COG3914  40 ALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLEL--AALLLQALGRYEEALALYRRALA-----LNP--- 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 134 ECPELDCEEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEkqfSVDALKQAMELNSQNQYEKVLL 213
Cdd:COG3914 110 DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE---AIAALRRALELDPDNAEALNNL 186

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 214 ALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKG---NLDRAIEFLGKALRSTANNSPLYSLVMCRY-REKL 289
Cdd:COG3914 187 GNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACdweVYDRFEELLAALARGPSELSPFALLYLPDDdPAEL 266


                ....*
gi 56090427 290 KQLQN 294
Cdd:COG3914 267 LALAR 271
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 63-269 7.66e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.36  E-value: 7.66e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  63 LDGENEAALECLGQaeDLRKSERSDRAE----------IKCLVTWGNYAWIYYRIGQLSEAQAYADKVRQVCQKFANPYs 132
Cdd:COG2956  71 RDPDRAEALLELAQ--DYLKAGLLDRAEelleklleldPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAY- 147

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 133 mecpeldCEEGWTRLKCGRNERAKMCFEKALEEKPEDPecRAGMAIA-MYRLQEKPEKqfSVDALKQAMELNSQNQYEKV 211
Cdd:COG2956 148 -------CELAELYLEQGDYDEAIEALEKALKLDPDCA--RALLLLAeLYLEQGDYEE--AIAALERALEQDPDYLPALP 216

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 56090427 212 LLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQkAAQFYRKKGNLDRAIEFLGKALR 269
Cdd:COG2956 217 RLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLERKEGLEAALALLERQLR 273
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 143-249 1.51e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 1.51e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 143 GWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEkqfSVDALKQAMELNSQNQYEKVLLALKLQKMGE 222
Cdd:COG4235  24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEE---AEELLERALALDPDNPEALYLLGLAAFQQGD 100

                        90       100
                ....*....|....*....|....*..
gi 56090427 223 EAEAERLVEDALEKGPNQTDVLQKAAQ 249
Cdd:COG4235 101 YAEAIAAWQKLLALLPADAPARLLEAS 127
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 179-336 1.91e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.15  E-value: 1.91e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 179 AMYRLQEKPEKQFSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLD 258
Cdd:COG3914  84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE 163

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56090427 259 RAIEFLGKALRSTANNSPLYSLvMCRYREKLKQLQntgEAdkserrqtmeelrrltMEYMNKALQRRPSPLNSYSDLI 336
Cdd:COG3914 164 EAIAALRRALELDPDNAEALNN-LGNALQDLGRLE---EA----------------IAAYRRALELDPDNADAHSNLL 221
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 162-383 7.16e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.61  E-value: 7.16e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 162 ALEEKPEDPECRAGMAIAMYRLQEKPEKQFSVDALKQAMELNSQNQYEKV----LLALKLQKMGEEAEAERLVEDALEKG 237
Cdd:COG3914  29 AAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAalleLAALLLQALGRYEEALALYRRALALN 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 238 PNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLYslvmCRYREKLKQLQNTGEAdkserrqtmeelrrltMEY 317
Cdd:COG3914 109 PDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAY----LNLGEALRRLGRLEEA----------------IAA 168

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56090427 318 MNKALQRRPSPL-------NSYSDLIDFPEVEKCYQMVFS--EESPRAEDQELFERY--CNLQEYHRKSEGLKALKD 383
Cdd:COG3914 169 LRRALELDPDNAealnnlgNALQDLGRLEEAIAAYRRALEldPDNADAHSNLLFALRqaCDWEVYDRFEELLAALAR 245
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
51-269 9.59e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.70  E-value: 9.59e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  51 ATMYDLLAYIKHLDGENEAALECLGQAEDLrksersdraEIKCLVTWGNYAWIYYRIGQLSEAQAYADKVRQVCQKFANP 130
Cdd:COG0457  42 AEALYNLGLAYLRLGRYEEALADYEQALEL---------DPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEA 112

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 131 YsmecpeldCEEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEKQFSVDALKQAMELNSQNQYEK 210
Cdd:COG0457 113 L--------YNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALG 184

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 56090427 211 VLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALR 269
Cdd:COG0457 185 EAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQY 243
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 100-238 1.09e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 51.11  E-value: 1.09e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 100 YAWIYYRIGQLSEAQAYADKVRQVCQKFANPYSMECPELDCEEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIA 179
Cdd:COG5010  18 TKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALL 97

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 56090427 180 MYRLQEKPEkqfSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGP 238
Cdd:COG5010  98 YSRSGDKDE---AKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 179-304 1.72e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.19  E-value: 1.72e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 179 AMYRLQEKPEKqfSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLD 258
Cdd:COG4783  12 QALLLAGDYDE--AEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 56090427 259 RAIEFLGKALRSTANNSPLYslvmCRYREKLKQLQNTGEADKSERR 304
Cdd:COG4783  90 EALALLEKALKLDPEHPEAY----LRLARAYRALGRPDEAIAALEK 131
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
163-278 4.46e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.78  E-value: 4.46e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 163 LEEKPEDPECRAGMAIAMYRLQEKPEkqfSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTD 242
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEE---AIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAE 77

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 56090427 243 VLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLY 278
Cdd:COG0457  78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEAL 113
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
150-239 6.56e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.09  E-value: 6.56e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 150 GRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEkqfsVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERL 229
Cdd:COG3063   6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDE----AIALEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                        90
                ....*....|
gi 56090427 230 VEDALEKGPN 239
Cdd:COG3063  82 LERALELDPS 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 56-278 6.57e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.62  E-value: 6.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427    56 LLAYIKHLDGENEAALECLGQAEDLRKSERSDRAeikclvtwgNYAWIYYRIGQLSEAQAYADKVRQvcqKFANPysmec 135
Cdd:TIGR02917 198 LKGDLLLSLGNIELALAAYRKAIALRPNNIAVLL---------ALATILIEAGEFEEAEKHADALLK---KAPNS----- 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   136 PELDCEEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQ--EKPEKQFSvDALKQAMElnsqNQYEKVLL 213
Cdd:TIGR02917 261 PLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGnlEQAYQYLN-QILKYAPN----SHQARRLL 335

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56090427   214 ALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLY 278
Cdd:TIGR02917 336 ASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAAR 400
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 47-236 2.21e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.96  E-value: 2.21e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  47 SEHKATMYDLLAYIKHLDGENEAALECLGQAEDLRkserSDRAEIKClvtwgNYAWIYYRIGQLSEAQAYADKVRQVCQK 126
Cdd:COG2956 106 DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLG----PENAHAYC-----ELAELYLEQGDYDEAIEALEKALKLDPD 176

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 127 FANPYSMEcpeldceeGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEkqfSVDALKQAMELNSQN 206
Cdd:COG2956 177 CARALLLL--------AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE---ALELLRKALELDPSD 245

                       170       180       190
                ....*....|....*....|....*....|
gi 56090427 207 qYEKVLLALKLQKMGEEAEAERLVEDALEK 236
Cdd:COG2956 246 -DLLLALADLLERKEGLEAALALLERQLRR 274
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 174-270 6.12e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.11  E-value: 6.12e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 174 AGMAIAMYRLQEKPEKqfSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRK 253
Cdd:COG5010  57 ESPSDNLYNKLGDFEE--SLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLS 134

                        90
                ....*....|....*..
gi 56090427 254 KGNLDRAIEFLGKALRS 270
Cdd:COG5010 135 LGQDDEAKAALQRALGT 151
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 143-288 1.08e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 1.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   143 GWTRLKCGRNERAKMCFEKALEEKPEDPEcrAGMAIAMYRL-QEKPEKQFSvdALKQAMELNSQNQYEKVLLALKLQKMG 221
Cdd:TIGR02917 370 GEAYLALGDFEKAAEYLAKATELDPENAA--ARTQLGISKLsQGDPSEAIA--DLETAAQLDPELGRADLLLILSYLRSG 445

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56090427   222 EEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSP-LYSLVMCRYREK 288
Cdd:TIGR02917 446 QFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPaAANLARIDIQEG 513
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
141-269 3.69e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.52  E-value: 3.69e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 141 EEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEkqfSVDALKQAMELNSQNQYEKVLLALKLQKM 220
Cdd:COG4785  78 ERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDA---ALEDFDRALELDPDYAYAYLNRGIALYYL 154

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56090427 221 GEEAEAERLVEDALEKGPN-----------QTDVLQKAAQF---------YRKKGNLDRAIEFLGKALR 269
Cdd:COG4785 155 GRYELAIADLEKALELDPNdperalwlylaERKLDPEKALAllledwataYLLQGDTEEARELFKLALA 223
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 204-278 6.28e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.49  E-value: 6.28e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56090427 204 SQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLY 278
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEAR 75
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 110-297 8.56e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 8.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   110 LSEAQAYADKVRQVCQKFANPYSMECP---ELDCEEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMA-IAMYR--- 182
Cdd:TIGR02917  96 LARAYLLQGKFQQVLDELPGKTLLDDEgaaELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAqLALAEnrf 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   183 ----------LQEKP-----------------EKQFSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALE 235
Cdd:TIGR02917 176 dearalidevLTADPgnvdalllkgdlllslgNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLK 255

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 56090427   236 KGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSP-LYSLVMCRYRekLKQLQNTGE 297
Cdd:TIGR02917 256 KAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPaLLLAGASEYQ--LGNLEQAYQ 316
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 54-203 1.11e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.25  E-value: 1.11e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  54 YDLLAYIKHLDGENEAALECLGQAEDLRKSERSDRAEIKCLVTWGNYAWIYYRIGQLSEAQAYADKVRQVCQKFANPYSm 133
Cdd:COG5010  14 LLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYY- 92

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 134 ecpeldcEEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEkqfSVDALKQAMELN 203
Cdd:COG5010  93 -------NLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDE---AKAALQRALGTS 152
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 48-300 1.20e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 1.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427    48 EHKATMYdLLAYIKHLDGENEAALECLGQAEdlrkseRSDRAEIKCLVTWGNYawiYYRIGQLSEAQAYADKVRQVCQKF 127
Cdd:TIGR02917 531 KNLRAIL-ALAGLYLRTGNEEEAVAWLEKAA------ELNPQEIEPALALAQY---YLGKGQLKKALAILNEAADAAPDS 600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   128 ANPYSMEcpeldceeGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEkqfSVDALKQAMELNSQNQ 207
Cdd:TIGR02917 601 PEAWLML--------GRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAK---AITSLKRALELKPDNT 669

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   208 YEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLYSLvmcryRE 287
Cdd:TIGR02917 670 EAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKL-----HR 744

                         250
                  ....*....|...
gi 56090427   288 KLKQLQNTGEADK 300
Cdd:TIGR02917 745 ALLASGNTAEAVK 757
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
217-278 2.31e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 2.31e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 56090427 217 LQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLgKALRSTANNSPLY 278
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALE-KALKLDPNNAEAL 62
TPR_19 pfam14559
Tetratricopeptide repeat;
221-281 5.16e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.95  E-value: 5.16e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56090427   221 GEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLYSLV 281
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALL 62
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 173-279 5.70e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.33  E-value: 5.70e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 173 RAGMAIAMYRLQEKPEKQFSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYR 252
Cdd:COG5010  20 LRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYS 99

                        90       100
                ....*....|....*....|....*..
gi 56090427 253 KKGNLDRAIEFLGKALRSTANNSPLYS 279
Cdd:COG5010 100 RSGDKDEAKEYYEKALALSPDNPNAYS 126
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 54-169 7.21e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.40  E-value: 7.21e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427  54 YDLLAYIKHLDGENEAALECLGQAEDLRKSERSdraeikclvTWGNYAWIYYRIGQLSEAQAYADKVRQvcqkfANPysm 133
Cdd:COG4783  41 FALLGEILLQLGDLDEAIVLLHEALELDPDEPE---------ARLNLGLALLKAGDYDEALALLEKALK-----LDP--- 103

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 56090427 134 ECPELDCEEGWTRLKCGRNERAKMCFEKALEEKPED 169
Cdd:COG4783 104 EHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR_12 pfam13424
Tetratricopeptide repeat;
51-126 9.37e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 9.37e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56090427    51 ATMYDLLAYIKHLDGENEAALECLGQAEDLRKSERSDRAEIKcLVTWGNYAWIYYRIGQLSEAQAYADKVRQVCQK 126
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLT-ATTLLNLGRLYLELGRYEEALELLERALALAEK 77
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 147-304 9.83e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 9.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   147 LKCGRNERAKMCFEKALEEKPEDPECRAGMAiAMYRLQEKPEKqfSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEA 226
Cdd:TIGR02917 510 IQEGNPDDAIQRFEKVLTIDPKNLRAILALA-GLYLRTGNEEE--AVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKA 586

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56090427   227 ERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLYSLVMCRYREKlkqlQNTGEADKSERR 304
Cdd:TIGR02917 587 LAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVM----KNYAKAITSLKR 660
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 103-274 2.18e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 2.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   103 IYYRIGQLSEAQAYADKVRQVCQKFANPYSmecpeldcEEGWTRLKCGRNERAKMCFEKALEEKPEDPecRAGMAIAMYR 182
Cdd:TIGR02917 372 AYLALGDFEKAAEYLAKATELDPENAAART--------QLGISKLSQGDPSEAIADLETAAQLDPELG--RADLLLILSY 441

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   183 LQEKPEKQfsvdALKQAMELNSQ---NQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDR 259
Cdd:TIGR02917 442 LRSGQFDK----ALAAAKKLEKKqpdNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDD 517

                         170
                  ....*....|....*
gi 56090427   260 AIEFLGKALRSTANN 274
Cdd:TIGR02917 518 AIQRFEKVLTIDPKN 532
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 30-268 2.68e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 2.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427    30 ISSHMEDRVCNQIENL--NSEHKATMYDLLAYIKHLDGENEAALECLGQAedlRKSERSDRAEIkclvtwGNYAWIYYRI 107
Cdd:TIGR02917 442 LRSGQFDKALAAAKKLekKQPDNASLHNLLGAIYLGKGDLAKAREAFEKA---LSIEPDFFPAA------ANLARIDIQE 512

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   108 GQLSEAQAYADKV-------RQVCQKFANPYsmecpeldceegwtrLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAm 180
Cdd:TIGR02917 513 GNPDDAIQRFEKVltidpknLRAILALAGLY---------------LRTGNEEEAVAWLEKAAELNPQEIEPALALAQY- 576

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   181 YRLQEKPEKQFSVdaLKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRA 260
Cdd:TIGR02917 577 YLGKGQLKKALAI--LNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKA 654


                  ....*...
gi 56090427   261 IEFLGKAL 268
Cdd:TIGR02917 655 ITSLKRAL 662
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 147-278 3.27e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 39.58  E-value: 3.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427   147 LKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEKQFSVDalkQAMELNSQNQYEKVLLALKLQKMGEEAEA 226
Cdd:TIGR00990 376 LELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQ---KSIDLDPDFIFSHIQLGVTQYKEGSIASS 452

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 56090427   227 ERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLY 278
Cdd:TIGR00990 453 MATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMY 504
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 141-298 7.78e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 37.97  E-value: 7.78e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 141 EEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPEKQfsvDALKQAMELNSQNQYEKVLLALKLQKM 220
Cdd:COG3071  21 LEGLLALAEGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYERRD---EYLAQALELAPEAELAVLLTRAELLLD 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090427 221 GEEAE-AERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLYSLVMCR-YREKLKQLQNTGEA 298
Cdd:COG3071  98 QGQAEqALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKHKALSAEEAQALERRaYLGLLRQAARDAEA 177
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 207-278 8.49e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 37.79  E-value: 8.49e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 56090427 207 QYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLY 278
Cdd:COG2956   8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEAL 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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