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Conserved domains on  [gi|70608165|ref|NP_001020448|]
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BUD13 homolog [Rattus norvegicus]

Protein Classification

PHA03307 and Bud13 domain-containing protein( domain architecture ID 13362399)

PHA03307 and Bud13 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bud13 pfam09736
Pre-mRNA-splicing factor of RES complex; This entry is characterized by proteins with ...
 477-619 1.65e-65

Pre-mRNA-splicing factor of RES complex; This entry is characterized by proteins with alternating conserved and low-complexity regions. Bud13 together with Snu17p and a newly identified factor, Pml1p/Ylr016c, form a novel trimeric complex. called The RES complex, pre-mRNA retention and splicing complex. Subunits of this complex are not essential for viability of yeasts but they are required for efficient splicing in vitro and in vivo. Furthermore, inactivation of this complex causes pre-mRNA leakage from the nucleus. Bud13 contains a unique, phylogenetically conserved C-terminal region of unknown function.


:

Pssm-ID: 462867 [Multi-domain]  Cd Length: 144  Bit Score: 211.67  E-value: 1.65e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   477 ETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQE 556
Cdd:pfam09736   1 ETVYRDKSGRRIDIEEERAEARRKAEEEEEKEEKYKEWGKGLVQKEEAEERREELEEEKSKPLARYADDEDLNEELKEQE 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 70608165   557 REGDPMANFIK--KNKAKENKNKKVRPRYNGPaPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLA 619
Cdd:pfam09736  81 RWGDPMAAFLTkkKSKGKKKTGFQGKPLYKGP-APPNRFGIRPGYRWDGVDRSNGFEKKWFKAQN 144
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 108-447 9.03e-11

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 65.19  E-value: 9.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   108 YSEDGHFHNDDQD--PSPPRKARHDTPDASPPRRVRHGTPEPSPPRRVRHDTPDPSPPRRVRHDSPDPSPTRRGHDSPDP 185
Cdd:PHA03307   37 SGSQGQLVSDSAElaAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDP 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   186 SPtRRVHHDSPDPSPPRRVRHDTPDPSPPRRVRHDTPDPSPPRRVRHDSDASPPRRSHRNSSAV-SPKRGHHGSSGTSSP 264
Cdd:PHA03307  117 PP-PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPeETARAPSSPPAEPPP 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   265 RQAHNHSPAAAQHRRTLDSSGAQHHRRARHDSPDLELPKAKSSKAAERPSSKTVSQSGLGP---PHPSLSMNSKYEHDSD 341
Cdd:PHA03307  196 STPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPlprPAPITLPTRIWEASGW 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   342 LSPPRKRQAKAHFGAKKQLDSKGVCQKASDSDLSPPRKNSKSGHQDSDSDLSPPRNR-PRRQSSDSDLSPPRRRQRTKSS 420
Cdd:PHA03307  276 NGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSsESSRGAAVSPGPSPSRSPSPSR 355

                         330       340
                  ....*....|....*....|....*..
gi 70608165   421 DSDLSPSRRSPRSGKKTPHMYSGAKTG 447
Cdd:PHA03307  356 PPPPADPSSPRKRPRPSRAPSSPAASA 382
 
Name Accession Description Interval E-value
Bud13 pfam09736
Pre-mRNA-splicing factor of RES complex; This entry is characterized by proteins with ...
 477-619 1.65e-65

Pre-mRNA-splicing factor of RES complex; This entry is characterized by proteins with alternating conserved and low-complexity regions. Bud13 together with Snu17p and a newly identified factor, Pml1p/Ylr016c, form a novel trimeric complex. called The RES complex, pre-mRNA retention and splicing complex. Subunits of this complex are not essential for viability of yeasts but they are required for efficient splicing in vitro and in vivo. Furthermore, inactivation of this complex causes pre-mRNA leakage from the nucleus. Bud13 contains a unique, phylogenetically conserved C-terminal region of unknown function.


Pssm-ID: 462867 [Multi-domain]  Cd Length: 144  Bit Score: 211.67  E-value: 1.65e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   477 ETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQE 556
Cdd:pfam09736   1 ETVYRDKSGRRIDIEEERAEARRKAEEEEEKEEKYKEWGKGLVQKEEAEERREELEEEKSKPLARYADDEDLNEELKEQE 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 70608165   557 REGDPMANFIK--KNKAKENKNKKVRPRYNGPaPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLA 619
Cdd:pfam09736  81 RWGDPMAAFLTkkKSKGKKKTGFQGKPLYKGP-APPNRFGIRPGYRWDGVDRSNGFEKKWFKAQN 144
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 108-447 9.03e-11

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 65.19  E-value: 9.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   108 YSEDGHFHNDDQD--PSPPRKARHDTPDASPPRRVRHGTPEPSPPRRVRHDTPDPSPPRRVRHDSPDPSPTRRGHDSPDP 185
Cdd:PHA03307   37 SGSQGQLVSDSAElaAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDP 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   186 SPtRRVHHDSPDPSPPRRVRHDTPDPSPPRRVRHDTPDPSPPRRVRHDSDASPPRRSHRNSSAV-SPKRGHHGSSGTSSP 264
Cdd:PHA03307  117 PP-PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPeETARAPSSPPAEPPP 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   265 RQAHNHSPAAAQHRRTLDSSGAQHHRRARHDSPDLELPKAKSSKAAERPSSKTVSQSGLGP---PHPSLSMNSKYEHDSD 341
Cdd:PHA03307  196 STPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPlprPAPITLPTRIWEASGW 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   342 LSPPRKRQAKAHFGAKKQLDSKGVCQKASDSDLSPPRKNSKSGHQDSDSDLSPPRNR-PRRQSSDSDLSPPRRRQRTKSS 420
Cdd:PHA03307  276 NGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSsESSRGAAVSPGPSPSRSPSPSR 355

                         330       340
                  ....*....|....*....|....*..
gi 70608165   421 DSDLSPSRRSPRSGKKTPHMYSGAKTG 447
Cdd:PHA03307  356 PPPPADPSSPRKRPRPSRAPSSPAASA 382
MSCRAMM_ClfB NF033845
MSCRAMM family adhesin clumping factor ClfB; Clumping factor B is an MSCRAMM (Microbial ...
 145-438 6.72e-08

MSCRAMM family adhesin clumping factor ClfB; Clumping factor B is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468203 [Multi-domain]  Cd Length: 871  Bit Score: 55.73  E-value: 6.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  145 PEPSPPRrvrhdTPDPSPprrvrhdSPDPSPTRRGHDSPDPSPtrrvhHDSPDPSPPRRVRHDTPDPSPPRRVRHDTPDP 224
Cdd:NF033845 546 PTPGPPV-----DPEPSP-------EPEPEPTPDPEPSPDPDP-----EPSPDPDPDSDSDSDSGSDSDSGSDSDSDSDS 608

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  225 SPPRRVRHDSDASPPRRSHRNSSAVSpkrGHHGSSGTSSPRQAHNHSPAAAQHRRTLDSSGAQHHRRARHDSpdlelpka 304
Cdd:NF033845 609 DSDSDSDSDSDSDSDSDSDSDSDSDS---DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDDSDSDSDSDSDS-------- 677

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  305 kSSKAAERPSSKTVSQSGLGPPHPSLSMNSKYEHDSDLSPPRKRQAKAHFGAKKQLDSKGVCQKASDSDLSPPRKNSKSG 384
Cdd:NF033845 678 -DSDSDSDSDSDSDSDSDSDSDSDSSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 756

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 70608165  385 HQDSDSDLSPPRNRPRRQSSDSDLSPPRRRQRTKSSDSDLSPSRRSPRSGKKTP 438
Cdd:NF033845 757 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSRVTPPNNEQKAP 810
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 116-333 1.63e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 48.07  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165    116 NDDQDPSPPRKARHDTPdASPPRRVRHGTPEPSPPRrVRHDTPDP------SPPRRVRHDSP--DPSPTRRGHDSPDPSP 187
Cdd:TIGR00927  129 NYSPTAAGTERVKEDTP-ATPSRALNHYISTSGRQR-VKSYTPKPrgevksSSPTQTREKVRkyTPSPLGRMVNSYAPST 206

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165    188 TR---RVHHDSP----------------DPSPPRRVRHDTpDPSPPRRVRHDTPD----------PSPPRRVRHDSDASP 238
Cdd:TIGR00927  207 FMtmpRSHGITPrttvkdseitatykmlETNPSKRTAGKT-TPTPLKGMTDNTPTfltrevetdlLTSPRSVVEKNTLTT 285

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165    239 PRRSHRNSSAvsPKRGHHGSSGTSSP-RQAHNHSPAAAQHRRTL---------DSSGAQHHRRARHDSPDLELPKAKSSK 308
Cdd:TIGR00927  286 PRRVESNSST--NHWGLVGKNNLTTPqGTVLEHTPATSEGQVTIsimtgsspaETKASTAAWKIRNPLSRTSAPAVRIAS 363

                          250       260
                   ....*....|....*....|....*
gi 70608165    309 AAERPSSKTVSQSGLGPPHPSLSMN 333
Cdd:TIGR00927  364 ATFRGLEKNPSTAPSTPATPRVRAV 388
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 220-423 7.14e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 39.51  E-value: 7.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  220 DTPD-PSPPRRVRHDSDASPPRRSHRNSSAVSPKRGHHGSSGTSSPRQAHNHSPAAAQHRRTLDSSGAQHHRRARHDSPD 298
Cdd:NF033609 546 EQPDePGEIEPIPEDSDSDPGSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 625

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  299 LELPKAKSSKAAERPSSKTVSQSGLGPPHPSLS-------MNSKYEHDSDLSPPRKRQAKAHFGAKKQLDSKGVCQKASD 371
Cdd:NF033609 626 SDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSdsdsdsdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 705

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 70608165  372 SDLSPPRKNSKSGHQDSDSDLSPPRNRPRRQSSDSDLSPPRRRQRTKSSDSD 423
Cdd:NF033609 706 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 757
 
Name Accession Description Interval E-value
Bud13 pfam09736
Pre-mRNA-splicing factor of RES complex; This entry is characterized by proteins with ...
 477-619 1.65e-65

Pre-mRNA-splicing factor of RES complex; This entry is characterized by proteins with alternating conserved and low-complexity regions. Bud13 together with Snu17p and a newly identified factor, Pml1p/Ylr016c, form a novel trimeric complex. called The RES complex, pre-mRNA retention and splicing complex. Subunits of this complex are not essential for viability of yeasts but they are required for efficient splicing in vitro and in vivo. Furthermore, inactivation of this complex causes pre-mRNA leakage from the nucleus. Bud13 contains a unique, phylogenetically conserved C-terminal region of unknown function.


Pssm-ID: 462867 [Multi-domain]  Cd Length: 144  Bit Score: 211.67  E-value: 1.65e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   477 ETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQE 556
Cdd:pfam09736   1 ETVYRDKSGRRIDIEEERAEARRKAEEEEEKEEKYKEWGKGLVQKEEAEERREELEEEKSKPLARYADDEDLNEELKEQE 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 70608165   557 REGDPMANFIK--KNKAKENKNKKVRPRYNGPaPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLA 619
Cdd:pfam09736  81 RWGDPMAAFLTkkKSKGKKKTGFQGKPLYKGP-APPNRFGIRPGYRWDGVDRSNGFEKKWFKAQN 144
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 108-447 9.03e-11

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 65.19  E-value: 9.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   108 YSEDGHFHNDDQD--PSPPRKARHDTPDASPPRRVRHGTPEPSPPRRVRHDTPDPSPPRRVRHDSPDPSPTRRGHDSPDP 185
Cdd:PHA03307   37 SGSQGQLVSDSAElaAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDP 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   186 SPtRRVHHDSPDPSPPRRVRHDTPDPSPPRRVRHDTPDPSPPRRVRHDSDASPPRRSHRNSSAV-SPKRGHHGSSGTSSP 264
Cdd:PHA03307  117 PP-PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPeETARAPSSPPAEPPP 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   265 RQAHNHSPAAAQHRRTLDSSGAQHHRRARHDSPDLELPKAKSSKAAERPSSKTVSQSGLGP---PHPSLSMNSKYEHDSD 341
Cdd:PHA03307  196 STPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPlprPAPITLPTRIWEASGW 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   342 LSPPRKRQAKAHFGAKKQLDSKGVCQKASDSDLSPPRKNSKSGHQDSDSDLSPPRNR-PRRQSSDSDLSPPRRRQRTKSS 420
Cdd:PHA03307  276 NGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSsESSRGAAVSPGPSPSRSPSPSR 355

                         330       340
                  ....*....|....*....|....*..
gi 70608165   421 DSDLSPSRRSPRSGKKTPHMYSGAKTG 447
Cdd:PHA03307  356 PPPPADPSSPRKRPRPSRAPSSPAASA 382
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 116-440 5.02e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 59.80  E-value: 5.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   116 NDDQDPSPPRKARHDTPDASPPRRVRHGTP-EPSPPRRVRHDTPDPSPPrrvrhDSPDPSPTRRGHDSPDPSPTRRVHHD 194
Cdd:PHA03307  110 GPSSPDPPPPTPPPASPPPSPAPDLSEMLRpVGSPGPPPAASPPAAGAS-----PAAVASDAASSRQAALPLSSPEETAR 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   195 SPDP--------SPPRRVRHDTPDPSPPRRVRHDTPDPSPPRrvrhDSDASPPRRSHRNSSAVSPKRGHHGSSGTSSPRQ 266
Cdd:PHA03307  185 APSSppaepppsTPPAAASPRPPRRSSPISASASSPAPAPGR----SAADDAGASSSDSSSSESSGCGWGPENECPLPRP 260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   267 AHNHSPaaaqhrRTLDSSGAQHHRRARHdspdlelPKAKSSKAAERPSSKTVSQSGLGPPHPSLSMNSKYE---HDSDLS 343
Cdd:PHA03307  261 APITLP------TRIWEASGWNGPSSRP-------GPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSsssRESSSS 327

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   344 PPRKRQAKAH---FGAKKQLDSKGVCQKASDS-DLSPPRKNSKSGHQDSDSDLSPPRNRPRRQSSDSDlspPRRRQRTKS 419
Cdd:PHA03307  328 STSSSSESSRgaaVSPGPSPSRSPSPSRPPPPaDPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVA---GRARRRDAT 404

                         330       340
                  ....*....|....*....|.
gi 70608165   420 SDSDLSPSRRSPRSGKKTPHM 440
Cdd:PHA03307  405 GRFPAGRPRPSPLDAGAASGA 425
MSCRAMM_ClfB NF033845
MSCRAMM family adhesin clumping factor ClfB; Clumping factor B is an MSCRAMM (Microbial ...
 145-438 6.72e-08

MSCRAMM family adhesin clumping factor ClfB; Clumping factor B is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468203 [Multi-domain]  Cd Length: 871  Bit Score: 55.73  E-value: 6.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  145 PEPSPPRrvrhdTPDPSPprrvrhdSPDPSPTRRGHDSPDPSPtrrvhHDSPDPSPPRRVRHDTPDPSPPRRVRHDTPDP 224
Cdd:NF033845 546 PTPGPPV-----DPEPSP-------EPEPEPTPDPEPSPDPDP-----EPSPDPDPDSDSDSDSGSDSDSGSDSDSDSDS 608

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  225 SPPRRVRHDSDASPPRRSHRNSSAVSpkrGHHGSSGTSSPRQAHNHSPAAAQHRRTLDSSGAQHHRRARHDSpdlelpka 304
Cdd:NF033845 609 DSDSDSDSDSDSDSDSDSDSDSDSDS---DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDDSDSDSDSDSDS-------- 677

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  305 kSSKAAERPSSKTVSQSGLGPPHPSLSMNSKYEHDSDLSPPRKRQAKAHFGAKKQLDSKGVCQKASDSDLSPPRKNSKSG 384
Cdd:NF033845 678 -DSDSDSDSDSDSDSDSDSDSDSDSSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 756

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 70608165  385 HQDSDSDLSPPRNRPRRQSSDSDLSPPRRRQRTKSSDSDLSPSRRSPRSGKKTP 438
Cdd:NF033845 757 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSRVTPPNNEQKAP 810
dnaA PRK14086
chromosomal replication initiator protein DnaA;
106-239 1.24e-06

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 51.75  E-value: 1.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  106 GGYSEDGHFHNDDqDPSPPRKARHDT-PDASP--PRRVRHGTPEPSPP-------RRVRHDTPDPSPPRRVRHDSPDPSP 175
Cdd:PRK14086 114 GRRPYEGYGGPRA-DDRPPGLPRQDQlPTARPayPAYQQRPEPGAWPRaaddygwQQQRLGFPPRAPYASPASYAPEQER 192

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 70608165  176 TRRGHDSPDPS---PTRRVHHDSPDPSPPRRVRHDTPDPSPPRRVRHDTPDPSPPRRVRHDSDASPP 239
Cdd:PRK14086 193 DREPYDAGRPEydqRRRDYDHPRPDWDRPRRDRTDRPEPPPGAGHVHRGGPGPPERDDAPVVPIRPS 259
dnaA PRK14086
chromosomal replication initiator protein DnaA;
134-340 3.57e-06

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 50.21  E-value: 3.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  134 ASPPRRVRHGTPEPSPPrrvrHDTPDPSPPRRVRHDSPDPSPTRRGHDSPDPSPTRRVHHDSPDPSP-PRrvrhdTPDPS 212
Cdd:PRK14086  95 PAPPPPHARRTSEPELP----RPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQQRPEPGAwPR-----AADDY 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  213 PPRRVRHDTPDPSPPRrvrhdSDASPPRRSHRNSSAVSPKRGHHGSSGTSSPRQAHNHSPAAAQHR-RTLDSSGAQH-HR 290
Cdd:PRK14086 166 GWQQQRLGFPPRAPYA-----SPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRPDWDRPRRDRTdRPEPPPGAGHvHR 240

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 70608165  291 RARHDSPDLELPKAKSSKAAERPSSKTvSQSGLGPPHPSLSMNSKYEHDS 340
Cdd:PRK14086 241 GGPGPPERDDAPVVPIRPSAPGPLAAQ-PAPAPGPGEPTARLNPKYTFDT 289
PHA03247 PHA03247
large tegument protein UL36; Provisional
 116-438 4.81e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.94  E-value: 4.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   116 NDDQDPSPPRKArhDTPDASPPRRVRHGTPEPSPPR---RVRHDTPDpSPPRRVRHDSP-DPSPTRRGHDSPDPSPtrrv 191
Cdd:PHA03247 2546 DDAGDPPPPLPP--AAPPAAPDRSVPPPRPAPRPSEpavTSRARRPD-APPQSARPRAPvDDRGDPRGPAPPSPLP---- 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   192 hhdsPDPSPPrrvrhDTPDPSP-PRRVRHDTPDPSP-PRRVRHDSDASPPRRShRNSSAVSPKRGHHGSSGTSSPRQ--- 266
Cdd:PHA03247 2619 ----PDTHAP-----DPPPPSPsPAANEPDPHPPPTvPPPERPRDDPAPGRVS-RPRRARRLGRAAQASSPPQRPRRraa 2688

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   267 --------------AHNHSPAAAQHRRTLDSSGAQHHRRARHDSPDLELPKAKSSkAAERPSSKTVSQSGLGPPHPSLSM 332
Cdd:PHA03247 2689 rptvgsltsladppPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPA-VPAGPATPGGPARPARPPTTAGPP 2767

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   333 NSKYEHDSDLSPPRKRQAKAHFGAKKQLDSKGVCQKASDSDLSPPRKNSKSGHQDSDSDLSPPRNRPRRQSSDSDLSPPR 412
Cdd:PHA03247 2768 APAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPP 2847

                         330       340
                  ....*....|....*....|....*.
gi 70608165   413 RRQRTKSSDSDLSPSRRSPRSGKKTP 438
Cdd:PHA03247 2848 PSLPLGGSVAPGGDVRRRPPSRSPAA 2873
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 116-333 1.63e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 48.07  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165    116 NDDQDPSPPRKARHDTPdASPPRRVRHGTPEPSPPRrVRHDTPDP------SPPRRVRHDSP--DPSPTRRGHDSPDPSP 187
Cdd:TIGR00927  129 NYSPTAAGTERVKEDTP-ATPSRALNHYISTSGRQR-VKSYTPKPrgevksSSPTQTREKVRkyTPSPLGRMVNSYAPST 206

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165    188 TR---RVHHDSP----------------DPSPPRRVRHDTpDPSPPRRVRHDTPD----------PSPPRRVRHDSDASP 238
Cdd:TIGR00927  207 FMtmpRSHGITPrttvkdseitatykmlETNPSKRTAGKT-TPTPLKGMTDNTPTfltrevetdlLTSPRSVVEKNTLTT 285

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165    239 PRRSHRNSSAvsPKRGHHGSSGTSSP-RQAHNHSPAAAQHRRTL---------DSSGAQHHRRARHDSPDLELPKAKSSK 308
Cdd:TIGR00927  286 PRRVESNSST--NHWGLVGKNNLTTPqGTVLEHTPATSEGQVTIsimtgsspaETKASTAAWKIRNPLSRTSAPAVRIAS 363

                          250       260
                   ....*....|....*....|....*
gi 70608165    309 AAERPSSKTVSQSGLGPPHPSLSMN 333
Cdd:TIGR00927  364 ATFRGLEKNPSTAPSTPATPRVRAV 388
PHA03132 PHA03132
thymidine kinase; Provisional
 81-239 2.42e-04

thymidine kinase; Provisional


Pssm-ID: 222997 [Multi-domain]  Cd Length: 580  Bit Score: 43.98  E-value: 2.42e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   81 EFVDERPEEVKQmEAFRSSTKWKLLGGY--SEDGHFHNDDQDPSPPRKARHDTPDASPPRRVRhgtPEPSPPRRVRHDTP 158
Cdd:PHA03132  15 DSSDESPEGSRD-ENFDAERDDFLTPLGstSEATSEDDDDLYPPRETGSGGGVATSTIYTVPR---PPRGPEQTLDKPDS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  159 DPSPPRRVRHDSPDPSPTRRGHDSPDPSPTRRVHHDSPDPSPPR----RVRHDTPDPSPPRRVRHDTPDPSPPRRVRHDS 234
Cdd:PHA03132  91 LPASRELPPGPTPVPPGGFRGASSPRLGADSTSPRFLYQVNFPVilapIGESNSSSEELSEEEEHSRPPPSESLKVKNGG 170


                 ....*
gi 70608165  235 DASPP 239
Cdd:PHA03132 171 KVYPK 175
PHA03247 PHA03247
large tegument protein UL36; Provisional
 123-263 2.54e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 2.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   123 PPRKARHDTPDASP-PRRVRHGTPEPSPPRRVRHDTPDPSPPRRVRHDSPDPSPTRRGHDSPDPSPTRRVHHDSPDPSPP 201
Cdd:PHA03247 2866 PPSRSPAAKPAAPArPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAP 2945

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 70608165   202 rrvrhdTPDPSPPRRVRHDTPDP-----SPPRRVRHDSDASPPRRSHRNSSAVSPKRGHHGSSGTSS 263
Cdd:PHA03247 2946 ------TTDPAGAGEPSGAVPQPwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
PHA03247 PHA03247
large tegument protein UL36; Provisional
 117-438 3.09e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 3.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   117 DDQDPSPPRkarhdtpdASPPRRVR---HGTPEPSPPRRVRHDT-PDPSPPRRVRHDSPDPSPTrrghdsPDPSPTRRVh 192
Cdd:PHA03247 2652 PRDDPAPGR--------VSRPRRARrlgRAAQASSPPQRPRRRAaRPTVGSLTSLADPPPPPPT------PEPAPHALV- 2716

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   193 HDSPDPSPPRRVRHDTP----DPSPPRRVRHDTPDPSPPRRVRHDSDASPPRRSH-RNSSAVSPKRGHHGSSGTSSPRQA 267
Cdd:PHA03247 2717 SATPLPPGPAAARQASPalpaAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPpAAPAAGPPRRLTRPAVASLSESRE 2796

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   268 HNHSPAAAQHRRTLDSSGAQHHRRARHDSPDLELPKAKSSKAAERPSsktvsqsglGPPHPSLSMNSKYEHDSDLS-PPR 346
Cdd:PHA03247 2797 SLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP---------GPPPPSLPLGGSVAPGGDVRrRPP 2867

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   347 KRQAKAHFGAKKQLDSKGVCQKA-SDSDLSPPRKNSKSGHQDSDSDLSPPRNRPRRQSSDSDLSPPRRRQRtksSDSDLS 425
Cdd:PHA03247 2868 SRSPAAKPAAPARPPVRRLARPAvSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR---PQPPLA 2944

                         330
                  ....*....|...
gi 70608165   426 PSRRSPRSGKKTP 438
Cdd:PHA03247 2945 PTTDPAGAGEPSG 2957
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 130-252 2.57e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.13  E-value: 2.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165    130 DTPDASPPRRVRHGTPEPS------PPRRVRHDTPdpSPPRRV---------RHDSPDPSPTRRGHDSPDPSPTRRVHHD 194
Cdd:TIGR00927   78 DPPKSSSEMEGEMLAPQATvgrdeaTPSIAMENTP--SPPRRTakitpttpkNNYSPTAAGTERVKEDTPATPSRALNHY 155

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 70608165    195 SPDPSPPrRVRHDTPDP------SPPRRVRHDTPDPSP-PRRVRHDSDASPPRRSHRNSSAVSPK 252
Cdd:TIGR00927  156 ISTSGRQ-RVKSYTPKPrgevksSSPTQTREKVRKYTPsPLGRMVNSYAPSTFMTMPRSHGITPR 219
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 121-249 3.68e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 3.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  121 PSPPRKARHDTPDASPPRRVRHGTPEPSPPRRVRHDTPDPSPPRRVRHDSPDPSPTRRGHDSPDPSPTRRVHHDSPDPSP 200
Cdd:PRK07764 683 PAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPP 762

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 70608165  201 PRRVRHDTPDPSPPrrvrhdtPDPSPPRRVRHDSDASPPRRSHRNSSAV 249
Cdd:PRK07764 763 APAPAAAPAAAPPP-------SPPSEEEEMAEDDAPSMDDEDRRDAEEV 804
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 120-218 4.85e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 39.79  E-value: 4.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  120 DPSPPRKARHDTPDASPPRRvrhGTPEPS-PPRRVRHDTPDPSPPRRvrhDSPDPSPTRRGHDSPDPSPTRRVHHDSPDP 198
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVR---PTPAPStRPKAAAAANIPPKEPVR---ETATPPPVPPRPVAPPVPHTPESAPKLTRA 434

                         90       100
                 ....*....|....*....|
gi 70608165  199 SPPRRVRHDTPDPSPPRRVR 218
Cdd:PRK14950 435 AIPVDEKPKYTPPAPPKEEE 454
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 220-423 7.14e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 39.51  E-value: 7.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  220 DTPD-PSPPRRVRHDSDASPPRRSHRNSSAVSPKRGHHGSSGTSSPRQAHNHSPAAAQHRRTLDSSGAQHHRRARHDSPD 298
Cdd:NF033609 546 EQPDePGEIEPIPEDSDSDPGSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 625

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  299 LELPKAKSSKAAERPSSKTVSQSGLGPPHPSLS-------MNSKYEHDSDLSPPRKRQAKAHFGAKKQLDSKGVCQKASD 371
Cdd:NF033609 626 SDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSdsdsdsdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 705

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 70608165  372 SDLSPPRKNSKSGHQDSDSDLSPPRNRPRRQSSDSDLSPPRRRQRTKSSDSD 423
Cdd:NF033609 706 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 757
PHA03309 PHA03309
transcriptional regulator ICP4; Provisional
 122-447 7.92e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 165564 [Multi-domain]  Cd Length: 2033  Bit Score: 39.45  E-value: 7.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   122 SPPRKARHDTPDASPPRRvRHGTPEPSP-PRRVRHDTPDPSPPRRVRHDSPDPSPTRRGHDSPDPSPTRRVHHDSPDPSP 200
Cdd:PHA03309 1569 SSSSSASHDRSPSSSSRR-RDGRPSSRRrPSRRMSARPPSRPPAAVILRASWRYAEEVAREMLDAAASRFDEADGEDPLP 1647

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   201 P-----RRVRHDTPDPSPPRRVRHDTPDPSPPRRVRHDSDASPprrshRNSSAVSPKRGHHGSSGTSSpRQAHNHSPAAA 275
Cdd:PHA03309 1648 PaacggKPIAPETLVALCEQRGRGPTSLPRAPTPRSGEALAAP-----RRSGAKDPRQGQYCPSARRS-EAPHSPSPRDV 1721

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   276 -----QHRRTLDSSGAQHHRRARHD-SPDLELPKAKSSKAAERPSSKTVSQSGLGPPHPSLSMNSKyEHDSDLSPPRKRQ 349
Cdd:PHA03309 1722 alrllERQQELNRQLLLELRRGSCEiSPSPRRRDAEGRRFGCRQDDDDGYDYEGGRESPERVLGRR-QSRRDSVPVRRRS 1800

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   350 AKAHFGAKKQLDSKGVCQKASDSDLSPPRKNSKSGHQDSDSDLSPPRNRPRRQSSDSDLSpPRRRQRTKSSdsdLSPSRR 429
Cdd:PHA03309 1801 GAANCGGRWMISAGRSSSSSSSSSSSSSSSPSSRPSRSATPSLSPSPSPPRRAPVDRSRS-GRRRERDRPS---ANPFRW 1876

                         330
                  ....*....|....*...
gi 70608165   430 SPRSGKKTPHMYSGAKTG 447
Cdd:PHA03309 1877 APRQRSRADHSPDGTAPG 1894
PHA03247 PHA03247
large tegument protein UL36; Provisional
 119-222 8.89e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.54  E-value: 8.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165   119 QDPSPPRKARHDTPDASPPRRVRHGTPEPSPPRRVRHDTPDPSPPRRVRHDSPDPSPtRRGHDSPDPSPTRRVHHDSPDP 198
Cdd:PHA03247 2906 ERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQP-WLGALVPGRVAVPRFRVPQPAP 2984

                          90       100
                  ....*....|....*....|....
gi 70608165   199 SPPrrvrhdTPDPSPPRRVRHDTP 222
Cdd:PHA03247 2985 SRE------APASSTPPLTGHSLS 3002
PHA03132 PHA03132
thymidine kinase; Provisional
 172-317 9.52e-03

thymidine kinase; Provisional


Pssm-ID: 222997 [Multi-domain]  Cd Length: 580  Bit Score: 38.98  E-value: 9.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70608165  172 DPSPTRRGHDSPDPSPTrrvhhdSPDPSPPRRVR-------HDTPDPSPPRRVRHDTPDPSPPRRVRHDSDASPPRRSHR 244
Cdd:PHA03132  52 DDLYPPRETGSGGGVAT------STIYTVPRPPRgpeqtldKPDSLPASRELPPGPTPVPPGGFRGASSPRLGADSTSPR 125

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 70608165  245 NSSAVSPKRGHHGSSGTSSPRQAHNHSPaaaQHRRTLDS-SGAQHHRRARHDSPDLELPKAKSSKAAERPSSKT 317
Cdd:PHA03132 126 FLYQVNFPVILAPIGESNSSSEELSEEE---EHSRPPPSeSLKVKNGGKVYPKGFSKHKTHKRSEFSGLTKKAA 196
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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