|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
270-777 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 722.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 270 IRMLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLGPFVQQNdEEVRPTICP--SCQGKGPFELNVENTVYH 347
Cdd:smart00350 5 IRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSG-RETEPTVCPprECQSPTPFSLNHERSTFI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 348 NYQRITMQESPNKVAAGRLPRSKDVILLGDLCDSCKPGDEIEVTGVYTNN-FDGSLNYKQGFPVFNTLIHANHITNKD-K 425
Cdd:smart00350 84 DFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpYGFKLNTVKGLPVFATYIEANHVRKLDyK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 426 MASD-------QLTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCG 498
Cdd:smart00350 164 RSFEdssfsvqSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDINILLCG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 499 DPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEA 578
Cdd:smart00350 244 DPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAIHEA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 579 MEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNH 658
Cdd:smart00350 324 MEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVVDLH 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 659 RTHHPdakkivkegdelEEDQMDErtgvRLIPQDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESMAT---GSVA 735
Cdd:smart00350 404 RYSHP------------EEDEAFE----PPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTesrSSIP 467
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 71997752 736 ITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVMLESFV 777
Cdd:smart00350 468 ITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
451-775 |
0e+00 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 671.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 451 RVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVG 530
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 531 LTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGG 610
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 611 RYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRTHHPDAKKIVKEGDELEEDQMDERTGVRLIP 690
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEDREGEEEKNQRQRPKETKVEPIP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 691 QDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIR 770
Cdd:cd17753 241 QELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMAIR 320
|
....*
gi 71997752 771 VMLES 775
Cdd:cd17753 321 VMLDS 325
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
171-773 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 600.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 171 RFKNFLRSFHEPGNKQtKYIQMIKSMAADNRESLEVSFTDLSDDNgeQNISYFLPEAPNEMLAIMDRAATEVVMNMYPFY 250
Cdd:NF040949 4 KFKEFIRTFRDSFGNE-KYKERIFEMIAMRKRSLVVDFNDLYMFD--PELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 251 SRVCNEIKVRISQLPVEEDIRMLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLG-PFVQQNDEEV--RPTI 327
Cdd:NF040949 81 AEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEwPEEEEESYEIvePPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 328 CPSCQGKGPFELNVENTVYHNYQRITMQESPNKVAAGRLPRSKDVILLGDLCDSCKPGDEIEVTGVYTNNFDGSLNyKQG 407
Cdd:NF040949 161 CPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSLK-KGS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 408 FPVFNTLIHANHITNKDKMASD-QLTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKH 486
Cdd:NF040949 240 RPIFKNYIEANHIEVSQKELEEvEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 487 RLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDK 566
Cdd:NF040949 320 RIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 567 MSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVE 646
Cdd:NF040949 400 MREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEER 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 647 DERLAKFVVGNHRthhpDAKKIVKEgdeleedqmdertgvrlIPQDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRK 726
Cdd:NF040949 480 DRRLARHILDVHS----GKEKVKPE-----------------IDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMRK 538
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 71997752 727 ESMATGS----VAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVML 773
Cdd:NF040949 539 SSKSSEDpdspIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLML 589
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
167-775 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 586.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 167 EIERRFKNFLRSFhepgnkqtKYIQMIKSMAAD--NRESLEVSFTDLsdDNGEQNISYFLPEAPNEMLaimdRAATEVVM 244
Cdd:COG1241 4 DLVDKFEEFLRRY--------KYRDEILELAQEypEKRSLVVDYNDL--YSFDPDLADDLLENPDEVL----EAAEEALR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 245 NMYPF-YSRVCNEIKVRISQLPVEEDIRMLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLgpFVQQNDEEV 323
Cdd:COG1241 70 EIDLEpYDVSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTET--YVPQTGEKL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 324 R-PTICPSCQGKGPFELNVENTVYHNYQRITMQESPNKVAAGRLPRSKDVILLGDLCDSCKPGDEIEVTGVYTNNFDGSL 402
Cdd:COG1241 148 QePHECPGCGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSG 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 403 NYKQgfPVFNTLIHANHITNKDK-MASDQLTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEAKN 481
Cdd:COG1241 228 RGKS--TIFDLYLEANSIEVEEKeFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKV 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 482 PGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQR-HPVTREWTLEAGAMVLADKGVCL 560
Cdd:COG1241 306 LPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRdDFGTGRWTLEAGALVLADGGLAC 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 561 IDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRD 640
Cdd:COG1241 386 IDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRD 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 641 SVDSVEDERLAKFVVGNHRthhpDAKKIVKEGDELEEDQMDErtgvrlIPQDLLRKYIIYAREKCHPTLPEQHSEKFSNI 720
Cdd:COG1241 466 KPDEERDRELARHILKVHR----AGELLEQEIEEETEEVKPE------IDPDLLRKYIAYARRNVFPVLTEEAKDLIEDF 535
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 71997752 721 FAQMRK-ESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVMLES 775
Cdd:COG1241 536 YVDMRKkGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSC 591
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
435-658 |
4.26e-140 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 414.62 E-value: 4.26e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 435 DIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHI 514
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 515 APRSVLTTGQGASAVGLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTS 594
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71997752 595 LHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNH 658
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
166-772 |
1.07e-87 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 299.22 E-value: 1.07e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 166 KEIERRFKNFLRSFHE--------------PGNKQTKY-IQMIKSMAADNRE---------SLEVSFTDLSDDNgeQNIS 221
Cdd:PTZ00111 86 EELSERFTNFLKNFTEfsdvlefkdeqqskPEYTELYYlWKLMNFIKENLRDhstgysrilPFEVDLMHVYSFD--KVLY 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 222 YFLPEAPNEMLAIMDRAAT----EVVMNMYPFYSRVCNEI--KVRISQLPVEEDIRMLRQVHLNMLIRTAGVVTIASGIL 295
Cdd:PTZ00111 164 KLLVTFPADCIAELDKVLVklfnELLSKHYSDLSLENNSFfpRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIV 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 296 PQLAVVKYDCVACGYLLGPFVQQNDEEV----------RPTICPSCQGKGPFELNVENTVYHNYQRITMQESPNKVAAGR 365
Cdd:PTZ00111 244 PEITMACFRCRGQKKIGLNDYQPCTCEHyeyviqgevnEPLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPD 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 366 LPRSKDVI--------------------LLGDLCDSCKPGDEIEVTG------VYTNNfdGSLNYKQGFPVFNTLIH--- 416
Cdd:PTZ00111 324 KDGLDNSVdnsglngeiymkdnevinlnLYDDLIDSVKTGDRVTVVGilkvtpIRTST--TRRTLKSLYTYFVNVIHvkv 401
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 417 -----ANHITNKDKMASDQ--LTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEA------KNPG 483
Cdd:PTZ00111 402 instnANQPEKGLKYLGNEndFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKnssdfnKSPD 481
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 484 AKHRL---RGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQ-RHPVTREWTLEAGAMVLADKGVC 559
Cdd:PTZ00111 482 ACYKVdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVC 561
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 560 LIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIR 639
Cdd:PTZ00111 562 CIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVL 641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 640 DSVDSVEDERLAKFVVGN----HRTHHPDAKKIVKEGDEL--EEDQMDERTGVRLIPQDLLRKYIIYAREKCHPTLPEQH 713
Cdd:PTZ00111 642 DHIDQDTDQLISLSIAKDfllpHMTGSGNDEDTYDRSNTMhvEDESLRSEKDYNKNDLDMLRMYIKFSKLHCFPKLSDEA 721
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 714 SEKFSNIFAQMRKESMAT----------------------GSVAITV--RHVESMIRLSEAHAKLHLRSYVNDEDCAAAI 769
Cdd:PTZ00111 722 KKVITREYVKMRQGNFQTsnldelehaqedddddlyyqssGTRMIYVssRMISSIIRISVSLARMRLSTVVTPADALQAV 801
|
...
gi 71997752 770 RVM 772
Cdd:PTZ00111 802 QIV 804
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
169-262 |
3.78e-20 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 85.81 E-value: 3.78e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 169 ERRFKNFLRSFHEPGNKQTKYIQMIKSMAADNRESLEVSFTDLSDDNgeQNISYFLPEAPNEMLAIMDRAATEVVMNMY- 247
Cdd:pfam14551 1 KRKFKDFLEEFREDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFD--PDLAEALLENPYEYLPLFEEALKEVVKELSe 78
|
90
....*....|....*.
gi 71997752 248 -PFYSRVCNEIKVRIS 262
Cdd:pfam14551 79 dPDYAEEEKEFQVRFY 94
|
|
| MCM2_N |
pfam12619 |
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is ... |
48-116 |
3.13e-13 |
|
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is typically between 138 and 153 amino acids in length. The family is found in association with pfam00493. Mini-chromosome maintenance (MCM) proteins are essential for DNA replication. These proteins use ATPase activity to perform this function.
Pssm-ID: 403724 Cd Length: 148 Bit Score: 67.82 E-value: 3.13e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 71997752 48 LFGDDMERDYREQPELDQYSESGMDDASDVGSLSVSARRAAEREMAQRDQLLDD------DALMYEDGDSEEVDT 116
Cdd:pfam12619 27 LFGDNMEDDYRQNPELDRYDLDDIDDEGDYEEMDAAERRRAEAQLNRRDRELGAarrrrpAAFLQDDDDEDDLDG 101
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
270-777 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 722.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 270 IRMLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLGPFVQQNdEEVRPTICP--SCQGKGPFELNVENTVYH 347
Cdd:smart00350 5 IRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSG-RETEPTVCPprECQSPTPFSLNHERSTFI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 348 NYQRITMQESPNKVAAGRLPRSKDVILLGDLCDSCKPGDEIEVTGVYTNN-FDGSLNYKQGFPVFNTLIHANHITNKD-K 425
Cdd:smart00350 84 DFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpYGFKLNTVKGLPVFATYIEANHVRKLDyK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 426 MASD-------QLTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCG 498
Cdd:smart00350 164 RSFEdssfsvqSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDINILLCG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 499 DPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEA 578
Cdd:smart00350 244 DPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAIHEA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 579 MEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNH 658
Cdd:smart00350 324 MEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVVDLH 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 659 RTHHPdakkivkegdelEEDQMDErtgvRLIPQDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESMAT---GSVA 735
Cdd:smart00350 404 RYSHP------------EEDEAFE----PPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTesrSSIP 467
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 71997752 736 ITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVMLESFV 777
Cdd:smart00350 468 ITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
451-775 |
0e+00 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 671.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 451 RVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVG 530
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 531 LTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGG 610
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 611 RYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRTHHPDAKKIVKEGDELEEDQMDERTGVRLIP 690
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEDREGEEEKNQRQRPKETKVEPIP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 691 QDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIR 770
Cdd:cd17753 241 QELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMAIR 320
|
....*
gi 71997752 771 VMLES 775
Cdd:cd17753 321 VMLDS 325
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
171-773 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 600.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 171 RFKNFLRSFHEPGNKQtKYIQMIKSMAADNRESLEVSFTDLSDDNgeQNISYFLPEAPNEMLAIMDRAATEVVMNMYPFY 250
Cdd:NF040949 4 KFKEFIRTFRDSFGNE-KYKERIFEMIAMRKRSLVVDFNDLYMFD--PELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 251 SRVCNEIKVRISQLPVEEDIRMLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLG-PFVQQNDEEV--RPTI 327
Cdd:NF040949 81 AEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEwPEEEEESYEIvePPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 328 CPSCQGKGPFELNVENTVYHNYQRITMQESPNKVAAGRLPRSKDVILLGDLCDSCKPGDEIEVTGVYTNNFDGSLNyKQG 407
Cdd:NF040949 161 CPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSLK-KGS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 408 FPVFNTLIHANHITNKDKMASD-QLTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKH 486
Cdd:NF040949 240 RPIFKNYIEANHIEVSQKELEEvEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 487 RLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDK 566
Cdd:NF040949 320 RIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 567 MSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVE 646
Cdd:NF040949 400 MREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEER 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 647 DERLAKFVVGNHRthhpDAKKIVKEgdeleedqmdertgvrlIPQDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRK 726
Cdd:NF040949 480 DRRLARHILDVHS----GKEKVKPE-----------------IDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMRK 538
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 71997752 727 ESMATGS----VAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVML 773
Cdd:NF040949 539 SSKSSEDpdspIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLML 589
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
167-775 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 586.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 167 EIERRFKNFLRSFhepgnkqtKYIQMIKSMAAD--NRESLEVSFTDLsdDNGEQNISYFLPEAPNEMLaimdRAATEVVM 244
Cdd:COG1241 4 DLVDKFEEFLRRY--------KYRDEILELAQEypEKRSLVVDYNDL--YSFDPDLADDLLENPDEVL----EAAEEALR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 245 NMYPF-YSRVCNEIKVRISQLPVEEDIRMLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLgpFVQQNDEEV 323
Cdd:COG1241 70 EIDLEpYDVSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTET--YVPQTGEKL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 324 R-PTICPSCQGKGPFELNVENTVYHNYQRITMQESPNKVAAGRLPRSKDVILLGDLCDSCKPGDEIEVTGVYTNNFDGSL 402
Cdd:COG1241 148 QePHECPGCGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSG 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 403 NYKQgfPVFNTLIHANHITNKDK-MASDQLTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEAKN 481
Cdd:COG1241 228 RGKS--TIFDLYLEANSIEVEEKeFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKV 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 482 PGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQR-HPVTREWTLEAGAMVLADKGVCL 560
Cdd:COG1241 306 LPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRdDFGTGRWTLEAGALVLADGGLAC 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 561 IDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRD 640
Cdd:COG1241 386 IDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRD 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 641 SVDSVEDERLAKFVVGNHRthhpDAKKIVKEGDELEEDQMDErtgvrlIPQDLLRKYIIYAREKCHPTLPEQHSEKFSNI 720
Cdd:COG1241 466 KPDEERDRELARHILKVHR----AGELLEQEIEEETEEVKPE------IDPDLLRKYIAYARRNVFPVLTEEAKDLIEDF 535
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 71997752 721 FAQMRK-ESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVMLES 775
Cdd:COG1241 536 YVDMRKkGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSC 591
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
454-775 |
7.38e-142 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 422.91 E-value: 7.38e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 454 SSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTA 533
Cdd:cd17706 4 DSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAGLTA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 534 YVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYN 613
Cdd:cd17706 84 AVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGGRYN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 614 PTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRtHHPDAKKIVKEGDELEedqmdertgvrlIPQDL 693
Cdd:cd17706 164 PKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHR-GSDPEEQVKPEEDGIP------------IDIEL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 694 LRKYIIYAReKCHPTLPEQHSEKFSNIFAQMRKESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVML 773
Cdd:cd17706 231 LRKYILYAR-QIHPKISEEAREKLVRWYVELRKESERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVR 309
|
..
gi 71997752 774 ES 775
Cdd:cd17706 310 HS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
435-658 |
4.26e-140 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 414.62 E-value: 4.26e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 435 DIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHI 514
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 515 APRSVLTTGQGASAVGLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTS 594
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71997752 595 LHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNH 658
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
451-775 |
2.43e-124 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 377.88 E-value: 2.43e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 451 RVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVG 530
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 531 LTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGG 610
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 611 RYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRTHHPDAKKIVKEGDeleedqmdertgvrlIP 690
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQENEGE---------------IP 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 691 QDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRK-------ESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDE 763
Cdd:cd17756 226 ISKLKRYIAYCRAKCAPRLSEEAAEKLSNHYVTIRKdvrqnelESDNRSSIPITVRQLEAIIRISESLAKMELSPIATEK 305
|
330
....*....|..
gi 71997752 764 DCAAAIRVMLES 775
Cdd:cd17756 306 HVEEAIRLFQVS 317
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
450-773 |
3.43e-121 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 369.09 E-value: 3.43e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 450 QRVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAV 529
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 530 GLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIG 609
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 610 GRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRTHHPDAKKIVkegdeleedqmdertgvrlI 689
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIKPE-------------------I 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 690 PQDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESMATGS-VAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAA 768
Cdd:cd17761 222 DPDLLRKYIAYARKNVRPVLTEEAKQLIKDFYVEMRKSGQETPSpVPITARQLEALVRLSEASARMRLSQEVTLEDAERA 301
|
....*
gi 71997752 769 IRVML 773
Cdd:cd17761 302 IRIML 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
451-775 |
2.00e-117 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 359.44 E-value: 2.00e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 451 RVFSSIAPSIYGHDDVKRAIALALFRGEAKNPG-AKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAV 529
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTkTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 530 GLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIG 609
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 610 GRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHrthhpdakkIVKEGDELEEDqmdertgvrLI 689
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLY---------LEDTPEHIQDE---------VL 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 690 PQDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRK-ESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAA 768
Cdd:cd17755 223 DVEVLTDYISYAREHIHPKLSEEAAQELVQAYVDMRKmGSDARKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEA 302
|
....*..
gi 71997752 769 IRVMLES 775
Cdd:cd17755 303 VRLIREA 309
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
454-775 |
1.64e-110 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 341.27 E-value: 1.64e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 454 SSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTA 533
Cdd:cd17757 4 RSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGLTA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 534 YVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYN 613
Cdd:cd17757 84 AVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGRYD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 614 PTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRthhpdakkivkegdeLEEDQMDertgvRLIPQDL 693
Cdd:cd17757 164 RSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHS---------------KREEAIE-----PPFTAEQ 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 694 LRKYIIYAREKChPTLPEQHSEKFSNIFAQMRKESMATG---SVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIR 770
Cdd:cd17757 224 LKRYIAYARTFK-PKLTKEAKDELVEQYKELRQDDASGStrsSYRITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAAR 302
|
....*
gi 71997752 771 VMLES 775
Cdd:cd17757 303 LLKKS 307
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
451-772 |
1.85e-110 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 341.31 E-value: 1.85e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 451 RVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKhRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVG 530
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGM-KIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 531 LTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGG 610
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 611 RYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRThhpdakkivkegdeleEDQMDerTGVRLIP 690
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQH----------------NKQPD--SDFEPLD 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 691 QDLLRKYIIYAREKcHPTLPEQHSEKFSNIFAQMRKESMATGSVA-ITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAI 769
Cdd:cd17758 222 PKLLRAYIALAKRK-RPTVPPALADYIVQAYVEMRQEAKRSKDFTfTTPRTLLAILRLSQALARLRLSDSVEIDDVEEAL 300
|
...
gi 71997752 770 RVM 772
Cdd:cd17758 301 RLM 303
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
455-772 |
1.92e-104 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 325.19 E-value: 1.92e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 455 SIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAY 534
Cdd:cd17754 5 SLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGLTAA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 535 VQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNP 614
Cdd:cd17754 85 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGRYDV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 615 TRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRThhpdakkivkegdeleedqmdertgvrlipQDLL 694
Cdd:cd17754 165 YKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------IKFL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 695 RKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESMATGSVA----ITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIR 770
Cdd:cd17754 215 RKYIHYAKERIKPKLTQEAAEYIAEEYADLRNDDNTKTDKArtspITARTLETLIRLATAHAKARLSKTVDKVDAEVALN 294
|
..
gi 71997752 771 VM 772
Cdd:cd17754 295 LL 296
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
166-772 |
1.07e-87 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 299.22 E-value: 1.07e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 166 KEIERRFKNFLRSFHE--------------PGNKQTKY-IQMIKSMAADNRE---------SLEVSFTDLSDDNgeQNIS 221
Cdd:PTZ00111 86 EELSERFTNFLKNFTEfsdvlefkdeqqskPEYTELYYlWKLMNFIKENLRDhstgysrilPFEVDLMHVYSFD--KVLY 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 222 YFLPEAPNEMLAIMDRAAT----EVVMNMYPFYSRVCNEI--KVRISQLPVEEDIRMLRQVHLNMLIRTAGVVTIASGIL 295
Cdd:PTZ00111 164 KLLVTFPADCIAELDKVLVklfnELLSKHYSDLSLENNSFfpRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIV 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 296 PQLAVVKYDCVACGYLLGPFVQQNDEEV----------RPTICPSCQGKGPFELNVENTVYHNYQRITMQESPNKVAAGR 365
Cdd:PTZ00111 244 PEITMACFRCRGQKKIGLNDYQPCTCEHyeyviqgevnEPLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPD 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 366 LPRSKDVI--------------------LLGDLCDSCKPGDEIEVTG------VYTNNfdGSLNYKQGFPVFNTLIH--- 416
Cdd:PTZ00111 324 KDGLDNSVdnsglngeiymkdnevinlnLYDDLIDSVKTGDRVTVVGilkvtpIRTST--TRRTLKSLYTYFVNVIHvkv 401
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 417 -----ANHITNKDKMASDQ--LTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEA------KNPG 483
Cdd:PTZ00111 402 instnANQPEKGLKYLGNEndFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKnssdfnKSPD 481
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 484 AKHRL---RGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQ-RHPVTREWTLEAGAMVLADKGVC 559
Cdd:PTZ00111 482 ACYKVdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVC 561
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 560 LIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIR 639
Cdd:PTZ00111 562 CIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVL 641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 640 DSVDSVEDERLAKFVVGN----HRTHHPDAKKIVKEGDEL--EEDQMDERTGVRLIPQDLLRKYIIYAREKCHPTLPEQH 713
Cdd:PTZ00111 642 DHIDQDTDQLISLSIAKDfllpHMTGSGNDEDTYDRSNTMhvEDESLRSEKDYNKNDLDMLRMYIKFSKLHCFPKLSDEA 721
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 714 SEKFSNIFAQMRKESMAT----------------------GSVAITV--RHVESMIRLSEAHAKLHLRSYVNDEDCAAAI 769
Cdd:PTZ00111 722 KKVITREYVKMRQGNFQTsnldelehaqedddddlyyqssGTRMIYVssRMISSIIRISVSLARMRLSTVVTPADALQAV 801
|
...
gi 71997752 770 RVM 772
Cdd:PTZ00111 802 QIV 804
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
452-772 |
2.90e-83 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 269.42 E-value: 2.90e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 452 VFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGL 531
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 532 TAYVQRHpvTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPiGGR 611
Cdd:cd17760 82 TVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 612 YNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNhrthhpdaKKIVKEGDeleedqmdertgvRLIPQ 691
Cdd:cd17760 159 YDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILEN--------KGEPSKSS-------------KLWSM 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 692 DLLRKYIIYAReKCHPTLPEQHSEKFSNIFaQMRKESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRV 771
Cdd:cd17760 218 EKMRTYFCLIK-NLRPVLSDEANAILLRYY-QLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSV 295
|
.
gi 71997752 772 M 772
Cdd:cd17760 296 M 296
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
451-775 |
1.93e-81 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 264.01 E-value: 1.93e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 451 RVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHR--LRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASA 528
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRipIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 529 VGLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQdRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPI 608
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGSQ-HQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 609 GGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLakfvvgnhrTHHPdakkivkegdeleedqmdertgvrl 688
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLL---------SEHH------------------------- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 689 ipqDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAA 768
Cdd:cd17759 206 ---QLLRKYISYARQYVNPVLSKDASEALQEFYLELRKQNQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDV 282
|
....*..
gi 71997752 769 IRVMLES 775
Cdd:cd17759 283 IEIMKES 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
270-398 |
1.11e-46 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 162.65 E-value: 1.11e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 270 IRMLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLGPFVQQndeevrPTIC--PSCQGKGPFELNVENTVYH 347
Cdd:pfam17207 2 IRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKITE------PTKCpnPECGNKDPFKLVHEKSKFV 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 71997752 348 NYQRITMQESPNKVAAGRLPRSKDVILLGDLCDSCKPGDEIEVTGVYTNNF 398
Cdd:pfam17207 76 DFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
692-776 |
4.41e-34 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 125.35 E-value: 4.41e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 692 DLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESM-ATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIR 770
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTgSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIR 80
|
....*.
gi 71997752 771 VMLESF 776
Cdd:pfam17855 81 LLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
169-262 |
3.78e-20 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 85.81 E-value: 3.78e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 169 ERRFKNFLRSFHEPGNKQTKYIQMIKSMAADNRESLEVSFTDLSDDNgeQNISYFLPEAPNEMLAIMDRAATEVVMNMY- 247
Cdd:pfam14551 1 KRKFKDFLEEFREDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFD--PDLAEALLENPYEYLPLFEEALKEVVKELSe 78
|
90
....*....|....*.
gi 71997752 248 -PFYSRVCNEIKVRIS 262
Cdd:pfam14551 79 dPDYAEEEKEFQVRFY 94
|
|
| MCM2_N |
pfam12619 |
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is ... |
48-116 |
3.13e-13 |
|
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is typically between 138 and 153 amino acids in length. The family is found in association with pfam00493. Mini-chromosome maintenance (MCM) proteins are essential for DNA replication. These proteins use ATPase activity to perform this function.
Pssm-ID: 403724 Cd Length: 148 Bit Score: 67.82 E-value: 3.13e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 71997752 48 LFGDDMERDYREQPELDQYSESGMDDASDVGSLSVSARRAAEREMAQRDQLLDD------DALMYEDGDSEEVDT 116
Cdd:pfam12619 27 LFGDNMEDDYRQNPELDRYDLDDIDDEGDYEEMDAAERRRAEAQLNRRDRELGAarrrrpAAFLQDDDDEDDLDG 101
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
461-639 |
4.27e-06 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 47.53 E-value: 4.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 461 YGHDDVKRAIALALFRGEAKNpgakhrlrgdinVLLCGDPGTAKSQFLRYAAHIAPRS---VLTTgqGASAVGLTAYVQR 537
Cdd:cd00009 1 VGQEEAIEALREALELPPPKN------------LLLYGPPGTGKTTLARAIANELFRPgapFLYL--NASDLLEGLVVAE 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 538 HPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKagivtslHARCTVIAASNPiggrynptrt 617
Cdd:cd00009 67 LFGHFLVRLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLRID-------RENVRVIGATNR---------- 129
|
170 180
....*....|....*....|..
gi 71997752 618 fAENVDLTEPILSRFDVLCVIR 639
Cdd:cd00009 130 -PLLGDLDRALYDRLDIRIVIP 150
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
449-773 |
8.81e-06 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 48.63 E-value: 8.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 449 SQRVFSSIAPSIYGHDDVKRAIALALFrgeaknpgakhrLRGdiNVLLCGDPGTAKSQFLRYAAHiaprsvlTTG----- 523
Cdd:COG0714 3 EARLRAEIGKVYVGQEELIELVLIALL------------AGG--HLLLEGVPGVGKTTLAKALAR-------ALGlpfir 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 524 -QG------ASAVGLTAYVQRhpvTREWTLEAGAmVLAdkGVCLIDEFDkmsdqdRTSIH------EAMEQQSISIskAG 590
Cdd:COG0714 62 iQFtpdllpSDILGTYIYDQQ---TGEFEFRPGP-LFA--NVLLADEIN------RAPPKtqsallEAMEERQVTI--PG 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 591 IVTSLHARCTVIAASNPIGgrynPTRTFaenvDLTEPILSRFdvlcVIRDSVDSVEDERLAKFVVGNHRTHHPDAKKIVK 670
Cdd:COG0714 128 GTYKLPEPFLVIATQNPIE----QEGTY----PLPEAQLDRF----LLKLYIGYPDAEEEREILRRHTGRHLAEVEPVLS 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 671 EGDELEEDQMDERTGVRlipqDLLRKYIIyarekchptlpeqhsekfsNIFAQMRK-ESMATGSvaiTVRHVESMIRLSE 749
Cdd:COG0714 196 PEELLALQELVRQVHVS----EAVLDYIV-------------------DLVRATREhPDLRKGP---SPRASIALLRAAR 249
|
330 340
....*....|....*....|....
gi 71997752 750 AHAKLHLRSYVNDEDCAAAIRVML 773
Cdd:COG0714 250 ALALLDGRDYVTPDDVKAVAGPVL 273
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
493-632 |
6.06e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 43.82 E-value: 6.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 493 NVLLCGDPGTAKSQF-LRYAAHIAPRSVLTtgqgasaVGLTAYVQRHPVTREWTLEAGAMVLAD---------KGVCLID 562
Cdd:pfam07728 1 GVLLVGPPGTGKTELaERLAAALSNRPVFY-------VQLTRDTTEEDLFGRRNIDPGGASWVDgplvraareGEIAVLD 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71997752 563 EFDKMSDQDRTSIHEAMEQQSISISKAG--IVTSLHARcTVIAASNPIGGRYNptrtfaenvDLTEPILSRF 632
Cdd:pfam07728 74 EINRANPDVLNSLLSLLDERRLLLPDGGelVKAAPDGF-RLIATMNPLDRGLN---------ELSPALRSRF 135
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
460-634 |
4.25e-04 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 42.52 E-value: 4.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 460 IYGHDDVKRA--IALAlfrgeaknpgakhrlrGDINVLLCGDPGTAKSQFLRYAAHIAPRS----VLTTGQGASAVGLTA 533
Cdd:pfam01078 5 VKGQEQAKRAleIAAA----------------GGHNLLMIGPPGSGKTMLAKRLPGILPPLteaeALEVTAIHSVAGLGG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 534 yvQRHPVTR------EWTLEAGAMV------------LADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSL 595
Cdd:pfam01078 69 --DGGLIRRrpfrapHHSASAAALVgggsiprpgeisLAHNGVLFLDELPEFKRRVLESLRQPLEDGEITISRARAKVTF 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 71997752 596 HARCTVIAASNP-----IGGRYNPTRTFAENVD-----LTEPILSRFDV 634
Cdd:pfam01078 147 PARFQLVAAMNPcpcgyLGDPNKRCRCSPRQIRrylsrLSGPLLDRIDL 195
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
493-607 |
5.59e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.12 E-value: 5.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71997752 493 NVLLCGDPGTAKSQFLRYAAHIAPRS----VLTTGQGASAVGLTAYVQRHPVTREWTLEAGAMV-----LADK---GVCL 560
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPgggvIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLrlalaLARKlkpDVLI 83
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 71997752 561 IDEFDKMSDQDRtsiheAMEQQSISISKAGIVTSLHARCTVIAASNP 607
Cdd:smart00382 84 LDEITSLLDAEQ-----EALLLLLEELRLLLLLKSEKNLTVILTTND 125
|
|
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