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Conserved domains on  [gi|808355988|ref|NP_001023107|]
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Serpentine Receptor, class Z [Caenorhabditis elegans]

Protein Classification

class Z serpentine receptor( domain architecture ID 10563420)

class Z serpentine receptor (Srz) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Srz pfam10325
Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis ...
36-283 3.32e-60

Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srz is a solo families amongst the superfamilies of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'. The genes encoding Srz appear to be under strong adaptive evolutionary pressure.


:

Pssm-ID: 431214  Cd Length: 264  Bit Score: 193.58  E-value: 3.32e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808355988   36 MLSSMFFLICLMFLFPCYVYVNKINRQRDELTSLFPVTDHFYKMIKATNLLIAVVIICIIFTVISTSvVNSWLIFSILTI 115
Cdd:pfam10325   1 LLLLIILLIIYLLIFPFYVYVFKLNRERDKKTLLFPITNHFYKMVKISYFLFIFLIVILILIFFFSS-KNSIIGFIFLLL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808355988  116 TGLILFTLHVITQVFQILISLLAVRKFCFHFYPSHIESVLKVQKYILKFIWIFYLLKMITT---------------KENH 180
Cdd:pfam10325  80 IFLILYILYIITQVFHLLIFLLAIQRFLIYFFPSTEKYVLISQKYLHKYIWILYLVFVLKDlilfllyvitfskslGWET 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808355988  181 SVILDLITFIVLNSLLVITSLLYIPIIIS-SKFKNSGPTEKNKSQQYLIWQTVFILIFKLTTILMLIIIFLYD-SEQAFV 258
Cdd:pfam10325 160 IKYVYLIIFIILNILLFLSALLYIPIMISiRKLSHLASAQLNKPQKYIFWQTITVLIFKSIYIPLFIFIFLIDfLSEFLI 239
                         250       260
                  ....*....|....*....|....*
gi 808355988  259 FHIIMVTDVMSTPLIVQISYLCNNK 283
Cdd:pfam10325 240 FSIISITDILTTPLIIQLSYLGCNK 264
 
Name Accession Description Interval E-value
7TM_GPCR_Srz pfam10325
Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis ...
36-283 3.32e-60

Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srz is a solo families amongst the superfamilies of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'. The genes encoding Srz appear to be under strong adaptive evolutionary pressure.


Pssm-ID: 431214  Cd Length: 264  Bit Score: 193.58  E-value: 3.32e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808355988   36 MLSSMFFLICLMFLFPCYVYVNKINRQRDELTSLFPVTDHFYKMIKATNLLIAVVIICIIFTVISTSvVNSWLIFSILTI 115
Cdd:pfam10325   1 LLLLIILLIIYLLIFPFYVYVFKLNRERDKKTLLFPITNHFYKMVKISYFLFIFLIVILILIFFFSS-KNSIIGFIFLLL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808355988  116 TGLILFTLHVITQVFQILISLLAVRKFCFHFYPSHIESVLKVQKYILKFIWIFYLLKMITT---------------KENH 180
Cdd:pfam10325  80 IFLILYILYIITQVFHLLIFLLAIQRFLIYFFPSTEKYVLISQKYLHKYIWILYLVFVLKDlilfllyvitfskslGWET 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808355988  181 SVILDLITFIVLNSLLVITSLLYIPIIIS-SKFKNSGPTEKNKSQQYLIWQTVFILIFKLTTILMLIIIFLYD-SEQAFV 258
Cdd:pfam10325 160 IKYVYLIIFIILNILLFLSALLYIPIMISiRKLSHLASAQLNKPQKYIFWQTITVLIFKSIYIPLFIFIFLIDfLSEFLI 239
                         250       260
                  ....*....|....*....|....*
gi 808355988  259 FHIIMVTDVMSTPLIVQISYLCNNK 283
Cdd:pfam10325 240 FSIISITDILTTPLIIQLSYLGCNK 264
 
Name Accession Description Interval E-value
7TM_GPCR_Srz pfam10325
Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis ...
36-283 3.32e-60

Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srz is a solo families amongst the superfamilies of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'. The genes encoding Srz appear to be under strong adaptive evolutionary pressure.


Pssm-ID: 431214  Cd Length: 264  Bit Score: 193.58  E-value: 3.32e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808355988   36 MLSSMFFLICLMFLFPCYVYVNKINRQRDELTSLFPVTDHFYKMIKATNLLIAVVIICIIFTVISTSvVNSWLIFSILTI 115
Cdd:pfam10325   1 LLLLIILLIIYLLIFPFYVYVFKLNRERDKKTLLFPITNHFYKMVKISYFLFIFLIVILILIFFFSS-KNSIIGFIFLLL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808355988  116 TGLILFTLHVITQVFQILISLLAVRKFCFHFYPSHIESVLKVQKYILKFIWIFYLLKMITT---------------KENH 180
Cdd:pfam10325  80 IFLILYILYIITQVFHLLIFLLAIQRFLIYFFPSTEKYVLISQKYLHKYIWILYLVFVLKDlilfllyvitfskslGWET 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808355988  181 SVILDLITFIVLNSLLVITSLLYIPIIIS-SKFKNSGPTEKNKSQQYLIWQTVFILIFKLTTILMLIIIFLYD-SEQAFV 258
Cdd:pfam10325 160 IKYVYLIIFIILNILLFLSALLYIPIMISiRKLSHLASAQLNKPQKYIFWQTITVLIFKSIYIPLFIFIFLIDfLSEFLI 239
                         250       260
                  ....*....|....*....|....*
gi 808355988  259 FHIIMVTDVMSTPLIVQISYLCNNK 283
Cdd:pfam10325 240 FSIISITDILTTPLIIQLSYLGCNK 264
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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