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Conserved domains on  [gi|71985405|ref|NP_001024458|]
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Protein abhd-3.2 [Caenorhabditis elegans]

Protein Classification

YheT family hydrolase( domain architecture ID 10785476)

YheT family hydrolase

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
47-366 2.12e-65

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


:

Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 210.39  E-value: 2.12e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  47 RILEQKYHPSWWCPFGTTQTVVRQIFRDCPSLPFTREIVEFDDGGAAGIDWLIPegADDTTPIVVFLPGITGStHDSSYV 126
Cdd:COG0429   3 LLSTSPFRPPWWLRNGHLQTIYPSLFRRRPALPYRRERLELPDGDFVDLDWSDP--PAPSKPLVVLLHGLEGS-SDSHYA 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 127 LHPVKEARDKGWKCVVVNPRGLGGVKLRTTRTYNAATPHDFAFIAKMINERYPDAKKLGCGFSMGG-MILWnYLAMTGEN 205
Cdd:COG0429  80 RGLARALYARGWDVVRLNFRGCGGEPNLLPRLYHSGDTEDLVWVLAHLRARYPYAPLYAVGFSLGGnLLLK-YLGEQGDD 158
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 206 A-DLDGGMIVSSPWDPLVASDSIECFIPQLIFNSFIaKNLVDMVRPYRELFKDMVDFDEVCRCNTVRGFDRSFVIPMYGF 284
Cdd:COG0429 159 ApPLKAAVAVSPPLDLAASADRLERGFNRLYQRYFL-RSLKRKLRRKLALFPGLIDLEALKRIRTLREFDDAYTAPLHGF 237
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 285 KSCDDYYRQATLATKVDKIKIPCVTLNSVDDYFSPVECIPTLDiMESDYVCGIITNHGGHTAFMESADPNARGMVEKLLS 364
Cdd:COG0429 238 KDAEDYYQRASALPFLPQIRVPTLILNAADDPFLPPECLPEAA-ELNPNVTLELTKHGGHVGFISGKSPGRRYWLERRIL 316

                ..
gi 71985405 365 QW 366
Cdd:COG0429 317 EF 318
 
Name Accession Description Interval E-value
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
47-366 2.12e-65

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 210.39  E-value: 2.12e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  47 RILEQKYHPSWWCPFGTTQTVVRQIFRDCPSLPFTREIVEFDDGGAAGIDWLIPegADDTTPIVVFLPGITGStHDSSYV 126
Cdd:COG0429   3 LLSTSPFRPPWWLRNGHLQTIYPSLFRRRPALPYRRERLELPDGDFVDLDWSDP--PAPSKPLVVLLHGLEGS-SDSHYA 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 127 LHPVKEARDKGWKCVVVNPRGLGGVKLRTTRTYNAATPHDFAFIAKMINERYPDAKKLGCGFSMGG-MILWnYLAMTGEN 205
Cdd:COG0429  80 RGLARALYARGWDVVRLNFRGCGGEPNLLPRLYHSGDTEDLVWVLAHLRARYPYAPLYAVGFSLGGnLLLK-YLGEQGDD 158
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 206 A-DLDGGMIVSSPWDPLVASDSIECFIPQLIFNSFIaKNLVDMVRPYRELFKDMVDFDEVCRCNTVRGFDRSFVIPMYGF 284
Cdd:COG0429 159 ApPLKAAVAVSPPLDLAASADRLERGFNRLYQRYFL-RSLKRKLRRKLALFPGLIDLEALKRIRTLREFDDAYTAPLHGF 237
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 285 KSCDDYYRQATLATKVDKIKIPCVTLNSVDDYFSPVECIPTLDiMESDYVCGIITNHGGHTAFMESADPNARGMVEKLLS 364
Cdd:COG0429 238 KDAEDYYQRASALPFLPQIRVPTLILNAADDPFLPPECLPEAA-ELNPNVTLELTKHGGHVGFISGKSPGRRYWLERRIL 316

                ..
gi 71985405 365 QW 366
Cdd:COG0429 317 EF 318
PLN02511 PLN02511
hydrolase
44-344 3.45e-54

hydrolase


Pssm-ID: 215282 [Multi-domain]  Cd Length: 388  Bit Score: 183.44  E-value: 3.45e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405   44 SNLRILEQKYHPSWWCPFGTTQTVVRQIFRDCPSLPFTREIVEFDDGGAAGIDWliPEGAD----DTTPIVVFLPGITGS 119
Cdd:PLN02511  35 PKFKSLERPYDAFPLLGNRHVETIFASFFRSLPAVRYRRECLRTPDGGAVALDW--VSGDDralpADAPVLILLPGLTGG 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  120 THDSsYVLHPVKEARDKGWKCVVVNPRGLGGVKLRTTRTYNAATPHDFAFIAKMINERYPDAKKLGCGFSMGGMILWNYL 199
Cdd:PLN02511 113 SDDS-YVRHMLLRARSKGWRVVVFNSRGCADSPVTTPQFYSASFTGDLRQVVDHVAGRYPSANLYAAGWSLGANILVNYL 191
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  200 AMTGENADLDGGMIVSSPWDpLVASDsiECFIPQL--IFNSFIAKNLVDMVRPYRELFKDM---VDFDEVCRCNTVRGFD 274
Cdd:PLN02511 192 GEEGENCPLSGAVSLCNPFD-LVIAD--EDFHKGFnnVYDKALAKALRKIFAKHALLFEGLggeYNIPLVANAKTVRDFD 268
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  275 RSFVIPMYGFKSCDDYYRQATLATKVDKIKIPCVTLNSVDDYFSPVECIPTLDIMESDYVCGIITNHGGH 344
Cdd:PLN02511 269 DGLTRVSFGFKSVDAYYSNSSSSDSIKHVRVPLLCIQAANDPIAPARGIPREDIKANPNCLLIVTPSGGH 338
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
108-256 6.88e-07

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 49.81  E-value: 6.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405   108 PIVVFLPGITGStHDSSYVLhpVKEARDKGWKCVVVNPRGLGgvklRTTRtynAATPHDFAF--IAKMIN---ERYPDAK 182
Cdd:pfam00561   1 PPVLLLHGLPGS-SDLWRKL--APALARDGFRVIALDLRGFG----KSSR---PKAQDDYRTddLAEDLEyilEALGLEK 70
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 71985405   183 KLGCGFSMGGMILWNYLAMTGENADldgGMIVSSPWDPlvASDSIECFIPQL-----IFNSFIAKNLVDMVRPYRELFK 256
Cdd:pfam00561  71 VNLVGHSMGGLIALAYAAKYPDRVK---ALVLLGALDP--PHELDEADRFILalfpgFFDGFVADFAPNPLGRLVAKLL 144
 
Name Accession Description Interval E-value
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
47-366 2.12e-65

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 210.39  E-value: 2.12e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  47 RILEQKYHPSWWCPFGTTQTVVRQIFRDCPSLPFTREIVEFDDGGAAGIDWLIPegADDTTPIVVFLPGITGStHDSSYV 126
Cdd:COG0429   3 LLSTSPFRPPWWLRNGHLQTIYPSLFRRRPALPYRRERLELPDGDFVDLDWSDP--PAPSKPLVVLLHGLEGS-SDSHYA 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 127 LHPVKEARDKGWKCVVVNPRGLGGVKLRTTRTYNAATPHDFAFIAKMINERYPDAKKLGCGFSMGG-MILWnYLAMTGEN 205
Cdd:COG0429  80 RGLARALYARGWDVVRLNFRGCGGEPNLLPRLYHSGDTEDLVWVLAHLRARYPYAPLYAVGFSLGGnLLLK-YLGEQGDD 158
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 206 A-DLDGGMIVSSPWDPLVASDSIECFIPQLIFNSFIaKNLVDMVRPYRELFKDMVDFDEVCRCNTVRGFDRSFVIPMYGF 284
Cdd:COG0429 159 ApPLKAAVAVSPPLDLAASADRLERGFNRLYQRYFL-RSLKRKLRRKLALFPGLIDLEALKRIRTLREFDDAYTAPLHGF 237
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 285 KSCDDYYRQATLATKVDKIKIPCVTLNSVDDYFSPVECIPTLDiMESDYVCGIITNHGGHTAFMESADPNARGMVEKLLS 364
Cdd:COG0429 238 KDAEDYYQRASALPFLPQIRVPTLILNAADDPFLPPECLPEAA-ELNPNVTLELTKHGGHVGFISGKSPGRRYWLERRIL 316

                ..
gi 71985405 365 QW 366
Cdd:COG0429 317 EF 318
PLN02511 PLN02511
hydrolase
44-344 3.45e-54

hydrolase


Pssm-ID: 215282 [Multi-domain]  Cd Length: 388  Bit Score: 183.44  E-value: 3.45e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405   44 SNLRILEQKYHPSWWCPFGTTQTVVRQIFRDCPSLPFTREIVEFDDGGAAGIDWliPEGAD----DTTPIVVFLPGITGS 119
Cdd:PLN02511  35 PKFKSLERPYDAFPLLGNRHVETIFASFFRSLPAVRYRRECLRTPDGGAVALDW--VSGDDralpADAPVLILLPGLTGG 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  120 THDSsYVLHPVKEARDKGWKCVVVNPRGLGGVKLRTTRTYNAATPHDFAFIAKMINERYPDAKKLGCGFSMGGMILWNYL 199
Cdd:PLN02511 113 SDDS-YVRHMLLRARSKGWRVVVFNSRGCADSPVTTPQFYSASFTGDLRQVVDHVAGRYPSANLYAAGWSLGANILVNYL 191
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  200 AMTGENADLDGGMIVSSPWDpLVASDsiECFIPQL--IFNSFIAKNLVDMVRPYRELFKDM---VDFDEVCRCNTVRGFD 274
Cdd:PLN02511 192 GEEGENCPLSGAVSLCNPFD-LVIAD--EDFHKGFnnVYDKALAKALRKIFAKHALLFEGLggeYNIPLVANAKTVRDFD 268
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  275 RSFVIPMYGFKSCDDYYRQATLATKVDKIKIPCVTLNSVDDYFSPVECIPTLDIMESDYVCGIITNHGGH 344
Cdd:PLN02511 269 DGLTRVSFGFKSVDAYYSNSSSSDSIKHVRVPLLCIQAANDPIAPARGIPREDIKANPNCLLIVTPSGGH 338
PRK10985 PRK10985
putative hydrolase; Provisional
108-347 4.65e-28

putative hydrolase; Provisional


Pssm-ID: 182883  Cd Length: 324  Bit Score: 111.97  E-value: 4.65e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  108 PIVVFLPGITGSTHdSSYVLHPVKEARDKGWKCVVVNPRGLGGVKLRTTRTYNAATPHDFAFIAKMINERYPDAKKLGCG 187
Cdd:PRK10985  59 PRLVLFHGLEGSFN-SPYAHGLLEAAQKRGWLGVVMHFRGCSGEPNRLHRIYHSGETEDARFFLRWLQREFGHVPTAAVG 137
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  188 FSMGGMILWNYLAMTGENADLDGGMIVSSPWDPLVASDSIEC----FIPQLIFNSfIAKNLVDMVRPYRELFKdmVDFDE 263
Cdd:PRK10985 138 YSLGGNMLACLLAKEGDDLPLDAAVIVSAPLMLEACSYRMEQgfsrVYQRYLLNL-LKANAARKLAAYPGTLP--INLAQ 214
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  264 VCRCNTVRGFDRSFVIPMYGFKSCDDYYRQATLATKVDKIKIPCVTLNSVDDYFSPVECIPTLDIMES--DYVcgiITNH 341
Cdd:PRK10985 215 LKSVRRLREFDDLITARIHGFADAIDYYRQCSALPLLNQIRKPTLIIHAKDDPFMTHEVIPKPESLPPnvEYQ---LTEH 291

                 ....*.
gi 71985405  342 GGHTAF 347
Cdd:PRK10985 292 GGHVGF 297
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
108-256 6.88e-07

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 49.81  E-value: 6.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405   108 PIVVFLPGITGStHDSSYVLhpVKEARDKGWKCVVVNPRGLGgvklRTTRtynAATPHDFAF--IAKMIN---ERYPDAK 182
Cdd:pfam00561   1 PPVLLLHGLPGS-SDLWRKL--APALARDGFRVIALDLRGFG----KSSR---PKAQDDYRTddLAEDLEyilEALGLEK 70
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 71985405   183 KLGCGFSMGGMILWNYLAMTGENADldgGMIVSSPWDPlvASDSIECFIPQL-----IFNSFIAKNLVDMVRPYRELFK 256
Cdd:pfam00561  71 VNLVGHSMGGLIALAYAAKYPDRVK---ALVLLGALDP--PHELDEADRFILalfpgFFDGFVADFAPNPLGRLVAKLL 144
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
103-223 1.51e-05

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 45.76  E-value: 1.51e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 103 ADDTTPIVVFLPGITGSthdSSYVLHPVKEARDKGWKCVVVNPRGLG--GVKLRTTRTYNAATpHDFAFIAKMINERyPD 180
Cdd:COG2267  24 AGSPRGTVVLVHGLGEH---SGRYAELAEALAAAGYAVLAFDLRGHGrsDGPRGHVDSFDDYV-DDLRAALDALRAR-PG 98
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 71985405 181 AKKLGCGFSMGGMILWNYLAMTGENADldgGMIVSSP---WDPLVA 223
Cdd:COG2267  99 LPVVLLGHSMGGLIALLYAARYPDRVA---GLVLLAPayrADPLLG 141
COG4099 COG4099
Predicted peptidase [General function prediction only];
97-224 2.62e-04

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 41.88  E-value: 2.62e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  97 WLIPEGADDTT--PIVVFLPGITGSTHDSSYVL-HP----VKEARDKGWKCVVVNPRglggvkLRTTRTYNAATPHD--F 167
Cdd:COG4099  37 LYLPKGYDPGKkyPLVLFLHGAGERGTDNEKQLtHGapkfINPENQAKFPAIVLAPQ------CPEDDYWSDTKALDavL 110
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 71985405 168 AFIAKMINERYPDAKKL-GCGFSMGGMILWNYLAmtgENADL-DGGMIVSSPWDPLVAS 224
Cdd:COG4099 111 ALLDDLIAEYRIDPDRIyLTGLSMGGYGTWDLAA---RYPDLfAAAVPICGGGDPANAA 166
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
108-200 3.69e-04

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 41.53  E-value: 3.69e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405 108 PIVVFLPGITGSthdsSYVLHPVKEARDKGWKCVVVNPRGLGgvklRTTRTYNAATPHDFA-FIAKMInerypDAKKLG- 185
Cdd:COG0596  24 PPVVLLHGLPGS----SYEWRPLIPALAAGYRVIAPDLRGHG----RSDKPAGGYTLDDLAdDLAALL-----DALGLEr 90
                        90
                ....*....|....*...
gi 71985405 186 ---CGFSMGGMILWNYLA 200
Cdd:COG0596  91 vvlVGHSMGGMVALELAA 108
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
99-229 1.83e-03

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 39.60  E-value: 1.83e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71985405  99 IPEGADDTT--PIVVFLPGITGS--THDSSYVLHPVkeARDKGWkcVVVNPRGLGGVKLRTTRTYNAATPH----DFAFI 170
Cdd:COG3509  43 VPAGYDGGAplPLVVALHGCGGSaaDFAAGTGLNAL--ADREGF--IVVYPEGTGRAPGRCWNWFDGRDQRrgrdDVAFI 118
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 71985405 171 AKMINE---RYP-DAKKL-GCGFSMGGMILWNYLAmtgENADL-DGGMIVSSPwdPLVASDSIEC 229
Cdd:COG3509 119 AALVDDlaaRYGiDPKRVyVTGLSAGGAMAYRLAC---EYPDVfAAVAPVAGL--PYGAASDAAC 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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