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Conserved domains on  [gi|148806863|ref|NP_001028557|]
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protein broad-minded [Mus musculus]

Protein Classification

TBC domain-containing protein; TBC and TLD domain-containing protein( domain architecture ID 10633145)

TBC (Tre-2, BUB2p, Cdc16p) domain-containing protein may perform a GTP-activator activity on Rab-like GTPases| TBC (Tre-2/Bub2/Cdc1) and TLD domain-containing protein may function as a GTPase activator protein of Rab-like small GTPases; similar to Drosophila melanogaster GTPase-activating protein skywalker

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BROMI pfam14961
Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase ...
 12-1293 0e+00

Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase (CCRK), together these proteins regulate ciliary membrane and axonemal growth.


:

Pssm-ID: 464406  Cd Length: 1292  Bit Score: 2275.06  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863    12 LQAMLRQLFQSVKEKITGAPSLECAEEILLRLEETDENFHNYEFVKYLRQHICNMLGSMIEEEMEKCTSDQNQGEDSGYD 91
Cdd:pfam14961    1 LQSLLRQLLQSVKEKISGAPSVECAEEILLHLEETDENFHNYEFVKYLRQYIESTLGSVIEEETEKCTSEEGQGEGSGQD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863    92 TVVQHVTKRTQESKEYKEMMHSLKNIMMVVVEAMINKFEEDETRSEDRQRKM---QSGSCCTDNCSDSDSSFNQSYKF-C 167
Cdd:pfam14961   81 TLVQAVTKRTRESKEYKEMMHSLKNVMMVVVESLINKFEEDQMRKEEMHRKSqheQLSSHYTDNCSDSDSSFNQSYTFmS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   168 QGKLRLILDQLDPGQPKEVRYEALQTLCSAPPSDVLSCENWTTLCEKLTTSLSDPDPMFTDRILKFYAQTFTLSPLHMTK 247
Cdd:pfam14961  161 QEQLQLIAEKLDPRQPKEVRWEALQTLCHAPPSDVLSCESWTSLRRNLMAALSDPDPALSDKILRFYAKTFSSSPLNITR 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   248 EIYTSLAKYLEVYFLSRENHLPTLSTGVDITSPNVTRLLKKVRLLNEYQKEAPSFWIRHPEKYMEEIVESTLSLLSVKHE 327
Cdd:pfam14961  241 EIYTSLAKHLESYFLSSKLSFPSLSAGLDINNPDVARLLKKIRLLNEFQKEVPSFWIRHPEKYMEEIVESTLSLLSLHHE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   328 QS--HLVPQKILDPIYFFALVDTKAVWFKKWMHAYYSRTAVLRLLEKKYKCLITTAVQQCVQYLELCEAMKADEI----L 401
Cdd:pfam14961  321 QGlnSPGSDKVLDPIYFLALLDIKATWFKKWMHGYYSRTVVLRLLEKKYKSLIVAAVQQCIDYFESCEASVDKTTeishS 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   402 RHPKHCGTKQKSFYySGQELQYIYFIHSLCLLGRLLIYTQGRKLFPIKLKNRKDSVSLTNLLVLFTQLIYYSPSCPKMTS 481
Cdd:pfam14961  401 SHQQHIGNKQRTFY-TGKELQYIYFVHSLCLLGRLLIYTQGRKLFPIKLKNRKDPVSLTDLLVLLIRLIYYSPSLPKETP 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   482 IMCSENYSPASMVTDVLRMLCDQKECAVECLYNSTVTEALLLPIHNLTKGTAAAPDCSETALIHIADILARIASVEEGLI 561
Cdd:pfam14961  480 HVGSDNYSPASLVMEVLQILCDRKECAAECLYQDTVIETLLQPIITLLNGKEAKLNCSETTLIHIADILARIASTERGLS 559

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   562 LLLYGENMNSSEEESLTGAHIIAKFSKKLLEEDISIFSGSEMLPVVKGAFISVCRQIYGTCEGLQVLLPYGLHESIAKAW 641
Cdd:pfam14961  560 LLLYGGNLSSAEEESISAAHVIVQFTKKLLDKEIPVLSGSELLPSLKGAFIFVCRQMYNTCEGLQVLLPYGLHESIAEAW 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   642 KKTSLLSERIPTPVEGSDSVSSVSQVSPNSVAWEDNLLDDLLNFAATPKGLLLLQRTGAINECVTFMLSQYAKKPQVNRQ 721
Cdd:pfam14961  640 KKASLLSERVPTPVPGADCSSSVSQESQNVVVWEETLLDNLLNFAATPKGLLLLQQTGAINECVTYMFSRFTKKLQVSRC 719

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   722 KKFGYEVLVVQVASTAAGAVALQNSGFISALITELWSNLECGRDDVRLTHPRATPVDPIDRSCQKSFLALVNLL-SYPAV 800
Cdd:pfam14961  720 EKFGYGVMVTQVAATAPGAVALQSSGFVRALVLELWSVLECGRDDVRVTHPKSTPVDPIDRSCQKSFLALVNLLsSYPAV 799

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   801 YELTANQELPNKAEYSLREVPTCIIDIMDRLIVLNSEAKIRSLLNYEQSHTFGLRLLSVVCCDLDALLLLEAQYQVSNML 880
Cdd:pfam14961  800 YELLGNQELPNKTEYSLREMPTSIIDLIDRLIIINSEAKIHSLFNYEQSHTFGLRLLSVLCCNLDSLLLLESQYNISEVL 879

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   881 LHAQEENTFEISENHRNFIIDGLSVERNHVLVRINLIGGPSERILPPRMLEKGDDPYPWPMFSSYPLPHCYQSEGPRSAD 960
Cdd:pfam14961  880 LQAQKENVTEPSGSEGEFIIDGLSVERNHILVRINLIGGPSERILPPRALQKGEDPYPWPMFSSYPLPKCYLPDVPRITD 959

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   961 LKQDNDIGNLLSCFKMSDKQTEWIENCRRQFCKTMKSKPDAVHGSALGELLEKFVLLLTENPSECYFPSVEYTATDANVK 1040
Cdd:pfam14961  960 TKQDSELSKFLSSSKNPEKQAEWMENCRRQFCKIMKTKPDTISGGVLAELLEKFVLHLSESPSECYFSSTEYKAADADVK 1039

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863  1041 NESLSSVQQLGMKMTVRYGRFLNLLKDGAENELALVLKHCEKFLKQQQSPVTSSLLCLQGNYAGHDWFVSSLFMIMLGDK 1120
Cdd:pfam14961 1040 NASLSSVQQLGVKMTIRYGKYLNLLKEDAENDLCLVLKHCEQFLKQQQVKVSSSLRCLQGGYPGHDWFASSVFLIMSGDK 1119

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863  1121 GKTFHFLQHFSRLLTSAFLWVPRLHNSRYLPVDTLGTGIHPIYFCSAHYIEMLLKAEVPLVFSAFHMSGFAPSQICLQWI 1200
Cdd:pfam14961 1120 ERSLSFLLRFSHLLVSAFLWPPRLHASIHLPADTAESGIHPVYSCTAHYVEMLLKAEVPLVFSAFRMSGFTPSQICLQWL 1199

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863  1201 TQCFWNYLDWIEICHYIATCVVLGPDYQVYVCIAVLKHLQRDILQHTQTQDLQVFLKEEALHGFRVSNYFEYMENLEQNY 1280
Cdd:pfam14961 1200 TQCFWNYLDWTEICHYIATCIFMGPDYQVYMCISILKHLQQEILQHTQTQDLQVFLKEEPIHGFRVSNYLEYMESLEQTY 1279

                         1290
                   ....*....|...
gi 148806863  1281 RPVLLRDMRSIRV 1293
Cdd:pfam14961 1280 RPMVLTDMRNIRV 1292
 
Name Accession Description Interval E-value
BROMI pfam14961
Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase ...
 12-1293 0e+00

Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase (CCRK), together these proteins regulate ciliary membrane and axonemal growth.


Pssm-ID: 464406  Cd Length: 1292  Bit Score: 2275.06  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863    12 LQAMLRQLFQSVKEKITGAPSLECAEEILLRLEETDENFHNYEFVKYLRQHICNMLGSMIEEEMEKCTSDQNQGEDSGYD 91
Cdd:pfam14961    1 LQSLLRQLLQSVKEKISGAPSVECAEEILLHLEETDENFHNYEFVKYLRQYIESTLGSVIEEETEKCTSEEGQGEGSGQD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863    92 TVVQHVTKRTQESKEYKEMMHSLKNIMMVVVEAMINKFEEDETRSEDRQRKM---QSGSCCTDNCSDSDSSFNQSYKF-C 167
Cdd:pfam14961   81 TLVQAVTKRTRESKEYKEMMHSLKNVMMVVVESLINKFEEDQMRKEEMHRKSqheQLSSHYTDNCSDSDSSFNQSYTFmS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   168 QGKLRLILDQLDPGQPKEVRYEALQTLCSAPPSDVLSCENWTTLCEKLTTSLSDPDPMFTDRILKFYAQTFTLSPLHMTK 247
Cdd:pfam14961  161 QEQLQLIAEKLDPRQPKEVRWEALQTLCHAPPSDVLSCESWTSLRRNLMAALSDPDPALSDKILRFYAKTFSSSPLNITR 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   248 EIYTSLAKYLEVYFLSRENHLPTLSTGVDITSPNVTRLLKKVRLLNEYQKEAPSFWIRHPEKYMEEIVESTLSLLSVKHE 327
Cdd:pfam14961  241 EIYTSLAKHLESYFLSSKLSFPSLSAGLDINNPDVARLLKKIRLLNEFQKEVPSFWIRHPEKYMEEIVESTLSLLSLHHE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   328 QS--HLVPQKILDPIYFFALVDTKAVWFKKWMHAYYSRTAVLRLLEKKYKCLITTAVQQCVQYLELCEAMKADEI----L 401
Cdd:pfam14961  321 QGlnSPGSDKVLDPIYFLALLDIKATWFKKWMHGYYSRTVVLRLLEKKYKSLIVAAVQQCIDYFESCEASVDKTTeishS 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   402 RHPKHCGTKQKSFYySGQELQYIYFIHSLCLLGRLLIYTQGRKLFPIKLKNRKDSVSLTNLLVLFTQLIYYSPSCPKMTS 481
Cdd:pfam14961  401 SHQQHIGNKQRTFY-TGKELQYIYFVHSLCLLGRLLIYTQGRKLFPIKLKNRKDPVSLTDLLVLLIRLIYYSPSLPKETP 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   482 IMCSENYSPASMVTDVLRMLCDQKECAVECLYNSTVTEALLLPIHNLTKGTAAAPDCSETALIHIADILARIASVEEGLI 561
Cdd:pfam14961  480 HVGSDNYSPASLVMEVLQILCDRKECAAECLYQDTVIETLLQPIITLLNGKEAKLNCSETTLIHIADILARIASTERGLS 559

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   562 LLLYGENMNSSEEESLTGAHIIAKFSKKLLEEDISIFSGSEMLPVVKGAFISVCRQIYGTCEGLQVLLPYGLHESIAKAW 641
Cdd:pfam14961  560 LLLYGGNLSSAEEESISAAHVIVQFTKKLLDKEIPVLSGSELLPSLKGAFIFVCRQMYNTCEGLQVLLPYGLHESIAEAW 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   642 KKTSLLSERIPTPVEGSDSVSSVSQVSPNSVAWEDNLLDDLLNFAATPKGLLLLQRTGAINECVTFMLSQYAKKPQVNRQ 721
Cdd:pfam14961  640 KKASLLSERVPTPVPGADCSSSVSQESQNVVVWEETLLDNLLNFAATPKGLLLLQQTGAINECVTYMFSRFTKKLQVSRC 719

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   722 KKFGYEVLVVQVASTAAGAVALQNSGFISALITELWSNLECGRDDVRLTHPRATPVDPIDRSCQKSFLALVNLL-SYPAV 800
Cdd:pfam14961  720 EKFGYGVMVTQVAATAPGAVALQSSGFVRALVLELWSVLECGRDDVRVTHPKSTPVDPIDRSCQKSFLALVNLLsSYPAV 799

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   801 YELTANQELPNKAEYSLREVPTCIIDIMDRLIVLNSEAKIRSLLNYEQSHTFGLRLLSVVCCDLDALLLLEAQYQVSNML 880
Cdd:pfam14961  800 YELLGNQELPNKTEYSLREMPTSIIDLIDRLIIINSEAKIHSLFNYEQSHTFGLRLLSVLCCNLDSLLLLESQYNISEVL 879

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   881 LHAQEENTFEISENHRNFIIDGLSVERNHVLVRINLIGGPSERILPPRMLEKGDDPYPWPMFSSYPLPHCYQSEGPRSAD 960
Cdd:pfam14961  880 LQAQKENVTEPSGSEGEFIIDGLSVERNHILVRINLIGGPSERILPPRALQKGEDPYPWPMFSSYPLPKCYLPDVPRITD 959

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   961 LKQDNDIGNLLSCFKMSDKQTEWIENCRRQFCKTMKSKPDAVHGSALGELLEKFVLLLTENPSECYFPSVEYTATDANVK 1040
Cdd:pfam14961  960 TKQDSELSKFLSSSKNPEKQAEWMENCRRQFCKIMKTKPDTISGGVLAELLEKFVLHLSESPSECYFSSTEYKAADADVK 1039

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863  1041 NESLSSVQQLGMKMTVRYGRFLNLLKDGAENELALVLKHCEKFLKQQQSPVTSSLLCLQGNYAGHDWFVSSLFMIMLGDK 1120
Cdd:pfam14961 1040 NASLSSVQQLGVKMTIRYGKYLNLLKEDAENDLCLVLKHCEQFLKQQQVKVSSSLRCLQGGYPGHDWFASSVFLIMSGDK 1119

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863  1121 GKTFHFLQHFSRLLTSAFLWVPRLHNSRYLPVDTLGTGIHPIYFCSAHYIEMLLKAEVPLVFSAFHMSGFAPSQICLQWI 1200
Cdd:pfam14961 1120 ERSLSFLLRFSHLLVSAFLWPPRLHASIHLPADTAESGIHPVYSCTAHYVEMLLKAEVPLVFSAFRMSGFTPSQICLQWL 1199

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863  1201 TQCFWNYLDWIEICHYIATCVVLGPDYQVYVCIAVLKHLQRDILQHTQTQDLQVFLKEEALHGFRVSNYFEYMENLEQNY 1280
Cdd:pfam14961 1200 TQCFWNYLDWTEICHYIATCIFMGPDYQVYMCISILKHLQQEILQHTQTQDLQVFLKEEPIHGFRVSNYLEYMESLEQTY 1279

                         1290
                   ....*....|...
gi 148806863  1281 RPVLLRDMRSIRV 1293
Cdd:pfam14961 1280 RPMVLTDMRNIRV 1292
 
Name Accession Description Interval E-value
BROMI pfam14961
Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase ...
 12-1293 0e+00

Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase (CCRK), together these proteins regulate ciliary membrane and axonemal growth.


Pssm-ID: 464406  Cd Length: 1292  Bit Score: 2275.06  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863    12 LQAMLRQLFQSVKEKITGAPSLECAEEILLRLEETDENFHNYEFVKYLRQHICNMLGSMIEEEMEKCTSDQNQGEDSGYD 91
Cdd:pfam14961    1 LQSLLRQLLQSVKEKISGAPSVECAEEILLHLEETDENFHNYEFVKYLRQYIESTLGSVIEEETEKCTSEEGQGEGSGQD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863    92 TVVQHVTKRTQESKEYKEMMHSLKNIMMVVVEAMINKFEEDETRSEDRQRKM---QSGSCCTDNCSDSDSSFNQSYKF-C 167
Cdd:pfam14961   81 TLVQAVTKRTRESKEYKEMMHSLKNVMMVVVESLINKFEEDQMRKEEMHRKSqheQLSSHYTDNCSDSDSSFNQSYTFmS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   168 QGKLRLILDQLDPGQPKEVRYEALQTLCSAPPSDVLSCENWTTLCEKLTTSLSDPDPMFTDRILKFYAQTFTLSPLHMTK 247
Cdd:pfam14961  161 QEQLQLIAEKLDPRQPKEVRWEALQTLCHAPPSDVLSCESWTSLRRNLMAALSDPDPALSDKILRFYAKTFSSSPLNITR 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   248 EIYTSLAKYLEVYFLSRENHLPTLSTGVDITSPNVTRLLKKVRLLNEYQKEAPSFWIRHPEKYMEEIVESTLSLLSVKHE 327
Cdd:pfam14961  241 EIYTSLAKHLESYFLSSKLSFPSLSAGLDINNPDVARLLKKIRLLNEFQKEVPSFWIRHPEKYMEEIVESTLSLLSLHHE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   328 QS--HLVPQKILDPIYFFALVDTKAVWFKKWMHAYYSRTAVLRLLEKKYKCLITTAVQQCVQYLELCEAMKADEI----L 401
Cdd:pfam14961  321 QGlnSPGSDKVLDPIYFLALLDIKATWFKKWMHGYYSRTVVLRLLEKKYKSLIVAAVQQCIDYFESCEASVDKTTeishS 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   402 RHPKHCGTKQKSFYySGQELQYIYFIHSLCLLGRLLIYTQGRKLFPIKLKNRKDSVSLTNLLVLFTQLIYYSPSCPKMTS 481
Cdd:pfam14961  401 SHQQHIGNKQRTFY-TGKELQYIYFVHSLCLLGRLLIYTQGRKLFPIKLKNRKDPVSLTDLLVLLIRLIYYSPSLPKETP 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   482 IMCSENYSPASMVTDVLRMLCDQKECAVECLYNSTVTEALLLPIHNLTKGTAAAPDCSETALIHIADILARIASVEEGLI 561
Cdd:pfam14961  480 HVGSDNYSPASLVMEVLQILCDRKECAAECLYQDTVIETLLQPIITLLNGKEAKLNCSETTLIHIADILARIASTERGLS 559

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   562 LLLYGENMNSSEEESLTGAHIIAKFSKKLLEEDISIFSGSEMLPVVKGAFISVCRQIYGTCEGLQVLLPYGLHESIAKAW 641
Cdd:pfam14961  560 LLLYGGNLSSAEEESISAAHVIVQFTKKLLDKEIPVLSGSELLPSLKGAFIFVCRQMYNTCEGLQVLLPYGLHESIAEAW 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   642 KKTSLLSERIPTPVEGSDSVSSVSQVSPNSVAWEDNLLDDLLNFAATPKGLLLLQRTGAINECVTFMLSQYAKKPQVNRQ 721
Cdd:pfam14961  640 KKASLLSERVPTPVPGADCSSSVSQESQNVVVWEETLLDNLLNFAATPKGLLLLQQTGAINECVTYMFSRFTKKLQVSRC 719

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   722 KKFGYEVLVVQVASTAAGAVALQNSGFISALITELWSNLECGRDDVRLTHPRATPVDPIDRSCQKSFLALVNLL-SYPAV 800
Cdd:pfam14961  720 EKFGYGVMVTQVAATAPGAVALQSSGFVRALVLELWSVLECGRDDVRVTHPKSTPVDPIDRSCQKSFLALVNLLsSYPAV 799

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   801 YELTANQELPNKAEYSLREVPTCIIDIMDRLIVLNSEAKIRSLLNYEQSHTFGLRLLSVVCCDLDALLLLEAQYQVSNML 880
Cdd:pfam14961  800 YELLGNQELPNKTEYSLREMPTSIIDLIDRLIIINSEAKIHSLFNYEQSHTFGLRLLSVLCCNLDSLLLLESQYNISEVL 879

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   881 LHAQEENTFEISENHRNFIIDGLSVERNHVLVRINLIGGPSERILPPRMLEKGDDPYPWPMFSSYPLPHCYQSEGPRSAD 960
Cdd:pfam14961  880 LQAQKENVTEPSGSEGEFIIDGLSVERNHILVRINLIGGPSERILPPRALQKGEDPYPWPMFSSYPLPKCYLPDVPRITD 959

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863   961 LKQDNDIGNLLSCFKMSDKQTEWIENCRRQFCKTMKSKPDAVHGSALGELLEKFVLLLTENPSECYFPSVEYTATDANVK 1040
Cdd:pfam14961  960 TKQDSELSKFLSSSKNPEKQAEWMENCRRQFCKIMKTKPDTISGGVLAELLEKFVLHLSESPSECYFSSTEYKAADADVK 1039

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863  1041 NESLSSVQQLGMKMTVRYGRFLNLLKDGAENELALVLKHCEKFLKQQQSPVTSSLLCLQGNYAGHDWFVSSLFMIMLGDK 1120
Cdd:pfam14961 1040 NASLSSVQQLGVKMTIRYGKYLNLLKEDAENDLCLVLKHCEQFLKQQQVKVSSSLRCLQGGYPGHDWFASSVFLIMSGDK 1119

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863  1121 GKTFHFLQHFSRLLTSAFLWVPRLHNSRYLPVDTLGTGIHPIYFCSAHYIEMLLKAEVPLVFSAFHMSGFAPSQICLQWI 1200
Cdd:pfam14961 1120 ERSLSFLLRFSHLLVSAFLWPPRLHASIHLPADTAESGIHPVYSCTAHYVEMLLKAEVPLVFSAFRMSGFTPSQICLQWL 1199

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148806863  1201 TQCFWNYLDWIEICHYIATCVVLGPDYQVYVCIAVLKHLQRDILQHTQTQDLQVFLKEEALHGFRVSNYFEYMENLEQNY 1280
Cdd:pfam14961 1200 TQCFWNYLDWTEICHYIATCIFMGPDYQVYMCISILKHLQQEILQHTQTQDLQVFLKEEPIHGFRVSNYLEYMESLEQTY 1279

                         1290
                   ....*....|...
gi 148806863  1281 RPVLLRDMRSIRV 1293
Cdd:pfam14961 1280 RPMVLTDMRNIRV 1292
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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