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Conserved domains on  [gi|79325237|ref|NP_001031704|]
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phosphatase-like protein [Arabidopsis thaliana]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11477409)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 1-351 0e+00

SGT1, suppressor of G2 allele of SKP1; Provisional


:

Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 623.73  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237    1 MAKELADKAKEAFVDDDFDVAVDLYSKAIDLDPNCAEFFADRAQAYIKLESFTaEAVADANKAIELDPSLTKAYLRKGTA 80
Cdd:PLN03088   1 MAKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFT-EAVADANKAIELDPSLAKAYLRKGTA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237   81 CMKLEEYRTAKTALEKGASITPSESKFKKLIDECNFLITEEEKDLVQPVPSTLPSSVTAPPVSELDVTPTA-----KYRH 155
Cdd:PLN03088  80 CMKLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEKDLVQPVPSDLPSSVTAPPVEEADATPVVppskpKYRH 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  156 EYYQKPEEVVVTVFAKGIPKQNVNIDFGEQILSVVIEVPGEDAYYLQPRLFGKIIPDKCKYEVLSTKIEICLAKADIITW 235
Cdd:PLN03088 160 EFYQKPEEVVVTVFAKGVPAENVNVDFGEQILSVVIEVPGEDAYHLQPRLFGKIIPDKCKYEVLSTKIEIRLAKAEPITW 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  236 ASLEHGKGPAVLPKPNVSSEVSQRPAYPSSKKVK-DWDKLEAEVKKQEKDEKLEGDAALNKFFREIYQNADEDMRRAMSK 314
Cdd:PLN03088 240 ASLEYGKGPAVLPKPNVSSEVSQRPAYPSSKKKKdDWDKLEAEVKKEEKDEKLDGDAALNKFFREIYQNADEDTRRAMMK 319

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 79325237  315 SFVESNGTVLSTNWQEVGTKTIESTPPDGMELKKWEI 351
Cdd:PLN03088 320 SFVESNGTVLSTNWKEVGSKKIEGSPPDGMELKKWEY 356
 
Name Accession Description Interval E-value
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 1-351 0e+00

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 623.73  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237    1 MAKELADKAKEAFVDDDFDVAVDLYSKAIDLDPNCAEFFADRAQAYIKLESFTaEAVADANKAIELDPSLTKAYLRKGTA 80
Cdd:PLN03088   1 MAKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFT-EAVADANKAIELDPSLAKAYLRKGTA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237   81 CMKLEEYRTAKTALEKGASITPSESKFKKLIDECNFLITEEEKDLVQPVPSTLPSSVTAPPVSELDVTPTA-----KYRH 155
Cdd:PLN03088  80 CMKLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEKDLVQPVPSDLPSSVTAPPVEEADATPVVppskpKYRH 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  156 EYYQKPEEVVVTVFAKGIPKQNVNIDFGEQILSVVIEVPGEDAYYLQPRLFGKIIPDKCKYEVLSTKIEICLAKADIITW 235
Cdd:PLN03088 160 EFYQKPEEVVVTVFAKGVPAENVNVDFGEQILSVVIEVPGEDAYHLQPRLFGKIIPDKCKYEVLSTKIEIRLAKAEPITW 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  236 ASLEHGKGPAVLPKPNVSSEVSQRPAYPSSKKVK-DWDKLEAEVKKQEKDEKLEGDAALNKFFREIYQNADEDMRRAMSK 314
Cdd:PLN03088 240 ASLEYGKGPAVLPKPNVSSEVSQRPAYPSSKKKKdDWDKLEAEVKKEEKDEKLDGDAALNKFFREIYQNADEDTRRAMMK 319

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 79325237  315 SFVESNGTVLSTNWQEVGTKTIESTPPDGMELKKWEI 351
Cdd:PLN03088 320 SFVESNGTVLSTNWKEVGSKKIEGSPPDGMELKKWEY 356
SGS pfam05002
SGS domain; This domain was thought to be unique to the SGT1-like proteins, but is also found ...
 269-349 1.51e-47

SGS domain; This domain was thought to be unique to the SGT1-like proteins, but is also found in calcyclin binding proteins.


Pssm-ID: 461514 [Multi-domain]  Cd Length: 81  Bit Score: 155.41  E-value: 1.51e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237   269 KDWDKLEAEVKKQEKDEKLEGDAALNKFFREIYQNADEDMRRAMSKSFVESNGTVLSTNWQEVGTKTIESTPPDGMELKK 348
Cdd:pfam05002   1 KDWDKLEKEDEKEEKEEKDGGDAALNAFFQKIYADADEDTRRAMMKSFVESNGTVLSTNWDEVGKKKVETKPPDGMEAKK 80


                  .
gi 79325237   349 W 349
Cdd:pfam05002  81 W 81
SGT1 COG5091
Suppressor of G2 allele of skp1 and related proteins [General function prediction only];
136-349 1.72e-32

Suppressor of G2 allele of skp1 and related proteins [General function prediction only];


Pssm-ID: 227422 [Multi-domain]  Cd Length: 368  Bit Score: 124.43  E-value: 1.72e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237 136 SVTAPPVSELDVTPTAKYRHEYYQKPEEVVVTVF--AKGIPKQNVNIDFGEQILSVVIEVPGEDAYYL-QPRLFGKIIPD 212
Cdd:COG5091 158 SPISPLKIETAPQESPKMEIAYDFSETSDTAIIFiyRPPVGDEQVSPVLEGNTLSISYQPRRLRLWNDiTISLYKEVYPD 237

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237 213 KCKYEVLSTKIEICLAKADIITWASLEhgKGPAVLPKPNVSSEVSQRPAYPSS-KKVKDWDKLEAEvkkQEKDEklEGDA 291
Cdd:COG5091 238 IRSIKSFSKRVEVHLRKVEMVRWGGLN--GRPADESSRLSDEGKNSDSATPKSsKKQDDWKELMVE---DSGDE--ENPS 310

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 79325237 292 ALNKFFREIYQNADEDMRRAMSKSFVESNGTVLSTNWQEVGTKTIESTPPDGMELKKW 349
Cdd:COG5091 311 VMDSLFQKLYQRADDDTRRAMMKSFYESNGTALSTDWDDVKSKTITTEPPEGMEPKHW 368
p23_CS_SGT1_like cd06466
p23_like domain similar to the C-terminal CHORD-SGT1 (CS) domain of Sgt1 (suppressor of G2 ...
 156-239 3.79e-30

p23_like domain similar to the C-terminal CHORD-SGT1 (CS) domain of Sgt1 (suppressor of G2 allele of Skp1). Sgt1 interacts with multiple protein complexes and has the features of a cochaperone. Human (h) Sgt1 interacts with both Hsp70 and Hsp90, and has been shown to bind Hsp90 through its CS domain. Saccharomyces cerevisiae (Sc) Sgt1 is a subunit of both core kinetochore and SCF (Skp1-Cul1-F-box) ubiquitin ligase complexes. Sgt1 is required for pathogen resistance in plants. ScSgt1 is needed for the G1/S and G2/M cell-cycle transitions, and for assembly of the core kinetochore complex (CBF3) via activation of Ctf13, the F-box protein. Binding of Hsp82 (a yeast Hsp90 homologue) to ScSgt1, promotes the binding of Sgt1 to Skp1 and of Skp1 to Ctf13. Some proteins in this group have an SGT1-specific (SGS) domain at the extreme C-terminus. The ScSgt1-SGS domain binds adenylate cyclase. The hSgt1-SGS domain interacts with some S100 family proteins, and studies suggest that the interaction of hSgt1 with Hsp90 and Hsp70 may be regulated by S100A6 in a Ca2+ dependent fashion. This group also includes the p23_like domains of Melusin and NAD(P)H cytochrome b5 (NCB5) oxidoreductase (OR). Melusin is a vertebrate protein which interacts with two splice variants of beta1 integrin, and NCB5OR plays a part in maintaining viable pancreatic beta cells.


Pssm-ID: 107223  Cd Length: 84  Bit Score: 110.37  E-value: 3.79e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237 156 EYYQKPEEVVVTVFAKGIPKQNVNIDFGEQILSVVIEVPGEDAYYLQPRLFGKIIPDKCKYEVLSTKIEICLAKADIITW 235
Cdd:cd06466   1 DWYQTDTSVTVTIYAKNVDKEDVKVEFNEQSLSVSIILPGGSEYQLELDLFGPIDPEQSKVSVLPTKVEITLKKAEPGSW 80


                ....
gi 79325237 236 ASLE 239
Cdd:cd06466  81 PSLE 84
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 2-90 4.46e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 41.89  E-value: 4.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237     2 AKELADKAKEAFVDDDFDVAVDLYSKAIDLDPNCAeFFADRAQAYIKLESFTaEAVADANKAIELDPSLTKAYLRKGTAC 81
Cdd:TIGR00990 127 AAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPDPV-YYSNRAACHNALGDWE-KVVEDTTAALELDPDYSKALNRRANAY 204


                  ....*....
gi 79325237    82 MKLEEYRTA 90
Cdd:TIGR00990 205 DGLGKYADA 213
 
Name Accession Description Interval E-value
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 1-351 0e+00

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 623.73  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237    1 MAKELADKAKEAFVDDDFDVAVDLYSKAIDLDPNCAEFFADRAQAYIKLESFTaEAVADANKAIELDPSLTKAYLRKGTA 80
Cdd:PLN03088   1 MAKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFT-EAVADANKAIELDPSLAKAYLRKGTA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237   81 CMKLEEYRTAKTALEKGASITPSESKFKKLIDECNFLITEEEKDLVQPVPSTLPSSVTAPPVSELDVTPTA-----KYRH 155
Cdd:PLN03088  80 CMKLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEKDLVQPVPSDLPSSVTAPPVEEADATPVVppskpKYRH 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  156 EYYQKPEEVVVTVFAKGIPKQNVNIDFGEQILSVVIEVPGEDAYYLQPRLFGKIIPDKCKYEVLSTKIEICLAKADIITW 235
Cdd:PLN03088 160 EFYQKPEEVVVTVFAKGVPAENVNVDFGEQILSVVIEVPGEDAYHLQPRLFGKIIPDKCKYEVLSTKIEIRLAKAEPITW 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  236 ASLEHGKGPAVLPKPNVSSEVSQRPAYPSSKKVK-DWDKLEAEVKKQEKDEKLEGDAALNKFFREIYQNADEDMRRAMSK 314
Cdd:PLN03088 240 ASLEYGKGPAVLPKPNVSSEVSQRPAYPSSKKKKdDWDKLEAEVKKEEKDEKLDGDAALNKFFREIYQNADEDTRRAMMK 319

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 79325237  315 SFVESNGTVLSTNWQEVGTKTIESTPPDGMELKKWEI 351
Cdd:PLN03088 320 SFVESNGTVLSTNWKEVGSKKIEGSPPDGMELKKWEY 356
SGS pfam05002
SGS domain; This domain was thought to be unique to the SGT1-like proteins, but is also found ...
 269-349 1.51e-47

SGS domain; This domain was thought to be unique to the SGT1-like proteins, but is also found in calcyclin binding proteins.


Pssm-ID: 461514 [Multi-domain]  Cd Length: 81  Bit Score: 155.41  E-value: 1.51e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237   269 KDWDKLEAEVKKQEKDEKLEGDAALNKFFREIYQNADEDMRRAMSKSFVESNGTVLSTNWQEVGTKTIESTPPDGMELKK 348
Cdd:pfam05002   1 KDWDKLEKEDEKEEKEEKDGGDAALNAFFQKIYADADEDTRRAMMKSFVESNGTVLSTNWDEVGKKKVETKPPDGMEAKK 80


                  .
gi 79325237   349 W 349
Cdd:pfam05002  81 W 81
SGT1 COG5091
Suppressor of G2 allele of skp1 and related proteins [General function prediction only];
136-349 1.72e-32

Suppressor of G2 allele of skp1 and related proteins [General function prediction only];


Pssm-ID: 227422 [Multi-domain]  Cd Length: 368  Bit Score: 124.43  E-value: 1.72e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237 136 SVTAPPVSELDVTPTAKYRHEYYQKPEEVVVTVF--AKGIPKQNVNIDFGEQILSVVIEVPGEDAYYL-QPRLFGKIIPD 212
Cdd:COG5091 158 SPISPLKIETAPQESPKMEIAYDFSETSDTAIIFiyRPPVGDEQVSPVLEGNTLSISYQPRRLRLWNDiTISLYKEVYPD 237

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237 213 KCKYEVLSTKIEICLAKADIITWASLEhgKGPAVLPKPNVSSEVSQRPAYPSS-KKVKDWDKLEAEvkkQEKDEklEGDA 291
Cdd:COG5091 238 IRSIKSFSKRVEVHLRKVEMVRWGGLN--GRPADESSRLSDEGKNSDSATPKSsKKQDDWKELMVE---DSGDE--ENPS 310

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 79325237 292 ALNKFFREIYQNADEDMRRAMSKSFVESNGTVLSTNWQEVGTKTIESTPPDGMELKKW 349
Cdd:COG5091 311 VMDSLFQKLYQRADDDTRRAMMKSFYESNGTALSTDWDDVKSKTITTEPPEGMEPKHW 368
p23_CS_SGT1_like cd06466
p23_like domain similar to the C-terminal CHORD-SGT1 (CS) domain of Sgt1 (suppressor of G2 ...
 156-239 3.79e-30

p23_like domain similar to the C-terminal CHORD-SGT1 (CS) domain of Sgt1 (suppressor of G2 allele of Skp1). Sgt1 interacts with multiple protein complexes and has the features of a cochaperone. Human (h) Sgt1 interacts with both Hsp70 and Hsp90, and has been shown to bind Hsp90 through its CS domain. Saccharomyces cerevisiae (Sc) Sgt1 is a subunit of both core kinetochore and SCF (Skp1-Cul1-F-box) ubiquitin ligase complexes. Sgt1 is required for pathogen resistance in plants. ScSgt1 is needed for the G1/S and G2/M cell-cycle transitions, and for assembly of the core kinetochore complex (CBF3) via activation of Ctf13, the F-box protein. Binding of Hsp82 (a yeast Hsp90 homologue) to ScSgt1, promotes the binding of Sgt1 to Skp1 and of Skp1 to Ctf13. Some proteins in this group have an SGT1-specific (SGS) domain at the extreme C-terminus. The ScSgt1-SGS domain binds adenylate cyclase. The hSgt1-SGS domain interacts with some S100 family proteins, and studies suggest that the interaction of hSgt1 with Hsp90 and Hsp70 may be regulated by S100A6 in a Ca2+ dependent fashion. This group also includes the p23_like domains of Melusin and NAD(P)H cytochrome b5 (NCB5) oxidoreductase (OR). Melusin is a vertebrate protein which interacts with two splice variants of beta1 integrin, and NCB5OR plays a part in maintaining viable pancreatic beta cells.


Pssm-ID: 107223  Cd Length: 84  Bit Score: 110.37  E-value: 3.79e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237 156 EYYQKPEEVVVTVFAKGIPKQNVNIDFGEQILSVVIEVPGEDAYYLQPRLFGKIIPDKCKYEVLSTKIEICLAKADIITW 235
Cdd:cd06466   1 DWYQTDTSVTVTIYAKNVDKEDVKVEFNEQSLSVSIILPGGSEYQLELDLFGPIDPEQSKVSVLPTKVEITLKKAEPGSW 80


                ....
gi 79325237 236 ASLE 239
Cdd:cd06466  81 PSLE 84
p23_like cd06463
Proteins containing this p23_like domain include p23 and its Saccharomyces cerevisiae (Sc) ...
 158-239 8.92e-20

Proteins containing this p23_like domain include p23 and its Saccharomyces cerevisiae (Sc) homolog Sba1. Both are co-chaperones for the heat shock protein (Hsp) 90. p23 binds Hsp90 and participates in the folding of a number of Hsp90 clients, including the progesterone receptor. p23 also has a passive chaperoning activity and in addition may participate in prostaglandin synthesis. Both p23 and Sba1p can regulate telomerase activity. This group includes domains similar to the C-terminal CHORD-SGT1 (CS) domain of suppressor of G2 allele of Skp1 (Sgt1). Sgt1 interacts with multiple protein complexes and has the features of a co-chaperone. Human (h) Sgt1 interacts with both Hsp70 and Hsp90, and has been shown to bind Hsp90 through its CS domain. Saccharomyces cerevisiae (Sc) Sgt1 is a subunit of both core kinetochore and SCF (Skp1-Cul1-F-box) ubiquitin ligase complexes. Sgt1 is required for pathogen resistance in plants. This group also includes the p23_like domains of human butyrate-induced transcript 1 (hB-ind1), NUD (nuclear distribution) C, Melusin, and NAD(P)H cytochrome b5 (NCB5) oxidoreductase (OR). hB-ind1 plays a role in the signaling pathway mediated by the small GTPase Rac1, NUDC is needed for nuclear movement, Melusin interacts with two splice variants of beta1 integrin, and NCB5OR plays a part in maintaining viable pancreatic beta cells.


Pssm-ID: 107220  Cd Length: 84  Bit Score: 82.33  E-value: 8.92e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237 158 YQKPEEVVVTVFAKGIPKQNVNIDFGEQILSVVIEVPGEDAYYLQPRLFGKIIPDKCKYEVLSTKIEICLAKAD-IITWA 236
Cdd:cd06463   2 YQTLDEVTITIPLKDVTKKDVKVEFTPKSLTVSVKGGGGKEYLLEGELFGPIDPEESKWTVEDRKIEITLKKKEpGEWWP 81


                ...
gi 79325237 237 SLE 239
Cdd:cd06463  82 RLE 84
p23_CS_hSgt1_like cd06489
p23_like domain similar to the C-terminal CS (CHORD-SGT1) domain of human (h) Sgt1 and related ...
 156-239 6.04e-19

p23_like domain similar to the C-terminal CS (CHORD-SGT1) domain of human (h) Sgt1 and related proteins. hSgt1 is a co-chaperone which has been shown to be elevated in HEp-2 cells as a result of stress conditions such as heat shock. It interacts with the heat shock proteins (HSPs) Hsp70 and Hsp90, and it expression pattern is synchronized with these two Hsps. The interaction with HSP90 has been shown to involve the hSgt1_CS domain, and appears to be required for correct kinetochore assembly and efficient cell division. Some proteins in this subgroup contain a tetratricopeptide repeat (TPR) HSP-binding domain N-terminal to this CS domain, and most proteins in this subgroup contain a Sgt1-specific (SGS) domain C-terminal to the CS domain. The SGS domain interacts with some S100 family proteins. Studies suggest that S100A6 modulates in a Ca2+ dependent manner the interactions of hSgt1 with Hsp90 and Hsp70. The yeast Sgt1 CS domain is not found in this subgroup.


Pssm-ID: 107239  Cd Length: 84  Bit Score: 80.11  E-value: 6.04e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237 156 EYYQKPEEVVVTVFAKGIPKQNVNIDFGEQILSVVIEVPGEDAYYLQPRLFGKIIPDKCKYEVLSTKIEICLAKADIITW 235
Cdd:cd06489   1 DWYQTESQVVITILIKNVKPEDVSVEFEKRELSATVKLPSGNDYSLKLHLLHPIVPEQSSYKILSTKIEIKLKKTEAIRW 80


                ....
gi 79325237 236 ASLE 239
Cdd:cd06489  81 SKLE 84
p23_melusin_like cd06488
p23_like domain similar to the C-terminal (tail) domain of vertebrate Melusin and related ...
 154-239 8.19e-14

p23_like domain similar to the C-terminal (tail) domain of vertebrate Melusin and related proteins. Melusin's tail domain interacts with the cytoplasmic domain of beta1-A and beta1-D isoforms of beta1 integrin, it does not bind other integrin beta subunits. Melusin is a muscle-specific protein expressed in skeletal and cardiac muscles but not in smooth muscle or other tissues. It is needed for heart hypertrophy following mechanical overload. The integrin-binding portion of this domain appears to be sequestered in the full length melusin protein, Ca2+ may modulate the protein's conformation exposing this binding site. This group includes Chordc1, also known as Chp-1, which is conserved from vertebrates to humans. Mammalian Chordc1 interacts with the heat shock protein (HSP) Hsp90 and is implicated in circadian and/or homeostatic mechanisms in the brain. The N-terminal portions of proteins belonging to this group contain two cysteine and histidine rich domain (CHORD) domains.


Pssm-ID: 107238  Cd Length: 87  Bit Score: 66.17  E-value: 8.19e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237 154 RHEYYQKPEEVVVTVFAKGI-PKQNVnIDFGEQILSVVIEVPGEDAYYLQPRLFGKIIPDKCKYEVLSTKIEICLAKADI 232
Cdd:cd06488   2 RHDWHQTGSHVVVSVYAKNSnPELSV-VEANSTVLTIHIVFEGNKEFQLDIELWGVIDVEKSSVNMLPTKVEIKLRKAEP 80


                ....*..
gi 79325237 233 ITWASLE 239
Cdd:cd06488  81 GSWAKLE 87
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
25-103 1.93e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 63.01  E-value: 1.93e-11
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 79325237  25 YSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPS 103
Cdd:COG4785  96 FDQALELDPDLAEAYNNRGLAYLLLGDY-DAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPN 173
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
24-103 2.08e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.10  E-value: 2.08e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPS 103
Cdd:COG0457  64 DYEQALELDPDDAEALNNLGLALQALGRY-EEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPD 142
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
24-103 2.89e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 2.89e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPS 103
Cdd:COG0457  30 DYEKALELDPDDAEALYNLGLAYLRLGRY-EEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPD 108
CS pfam04969
CS domain; The CS and CHORD (pfam04968) are fused into a single polypeptide chain in metazoans ...
 154-229 8.82e-11

CS domain; The CS and CHORD (pfam04968) are fused into a single polypeptide chain in metazoans but are found in separate proteins in plants; this is thought to be indicative of an interaction between CS and CHORD. It has been suggested that the CS domain is a binding module for HSP90, implying that CS domain-containing proteins are involved in recruiting heat shock proteins to multiprotein assemblies. Two CS domains are found at the N-terminus of Ubiquitin carboxyl-terminal hydrolase 19 (USP19), these domains may play a role in the interaction of USP19 with cellular inhibitor of apoptosis 2.


Pssm-ID: 461503  Cd Length: 76  Bit Score: 57.27  E-value: 8.82e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 79325237   154 RHEYYQKPEEVVVTVFAK--GIPKQNVNIDFGEQILSVVIevpGEDAYYLQPRLFGKIIPDKCKYEVLSTKIEICLAK 229
Cdd:pfam04969   2 RYDWYQTLDEVTITIPVKgaGIKKKDVKVNIKPRSLKVKI---KGGYELIDGELFHPIDPEESSWTIEGKKVEITLKK 76
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 24-102 5.58e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 57.28  E-value: 5.58e-10
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITP 102
Cdd:COG5010  76 LLEQALQLDPNNPELYYNLALLYSRSGDK-DEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
24-98 6.80e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.86  E-value: 6.80e-10
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGA 98
Cdd:COG0457  98 DYDKALELDPDDAEALYNLGLALLELGRY-DEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLE 171
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 25-110 8.18e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.17  E-value: 8.18e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  25 YSKAIDLDPNCAEFFADRAQAYIKLESfTAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPSE 104
Cdd:COG4235  40 YEKALRLDPDNADALLDLAEALLAAGD-TEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118


                ....*.
gi 79325237 105 SKFKKL 110
Cdd:COG4235 119 APARLL 124
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
29-102 1.76e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.71  E-value: 1.76e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 79325237  29 IDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITP 102
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRY-EEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDP 73
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 24-102 1.91e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.58  E-value: 1.91e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITP 102
Cdd:COG4783  26 LLEKALELDPDNPEAFALLGEILLQLGDL-DEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDP 103
ACD_sHsps_p23-like cd00298
This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small ...
 158-229 6.84e-09

This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small heat shock proteins (sHsps) and a similar domain found in p23-like proteins. sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is this ACD. sHsps are generally active as large oligomers consisting of multiple subunits, and are believed to be ATP-independent chaperones that prevent aggregation and are important in refolding in combination with other Hsps. p23 is a cochaperone of the Hsp90 chaperoning pathway. It binds Hsp90 and participates in the folding of a number of Hsp90 clients including the progesterone receptor. p23 also has a passive chaperoning activity. p23 in addition may act as the cytosolic prostaglandin E2 synthase. Included in this family is the p23-like C-terminal CHORD-SGT1 (CS) domain of suppressor of G2 allele of Skp1 (Sgt1) and the p23-like domains of human butyrate-induced transcript 1 (hB-ind1), NUD (nuclear distribution) C, Melusin, and NAD(P)H cytochrome b5 (NCB5) oxidoreductase (OR).


Pssm-ID: 107219  Cd Length: 80  Bit Score: 52.21  E-value: 6.84e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 79325237 158 YQKPEEVVVTVFAKGIPKQNVNIDFGEQILSVVIEVPGEDA-------YYLQPRLFGKIIPDKCKYEVLSTKIEICLAK 229
Cdd:cd00298   2 YQTDDEVVVTVDLPGVKKEDIKVEVEDNVLTISGKREEEEErersygeFERSFELPEDVDPEKSKASLENGVLEITLPK 80
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
24-103 8.97e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 52.09  E-value: 8.97e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVAdANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPS 103
Cdd:COG3063  14 YYEKALELDPDNADALNNLGLLLLEQGRY-DEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 24-107 1.37e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.15  E-value: 1.37e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPS 103
Cdd:COG3914 134 ALRRALALNPDFAEAYLNLGEALRRLGRL-EEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPD 212


                ....
gi 79325237 104 ESKF 107
Cdd:COG3914 213 NADA 216
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 24-104 1.56e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.89  E-value: 1.56e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPS 103
Cdd:COG4783  60 LLHEALELDPDEPEARLNLGLALLKAGDY-DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138


                .
gi 79325237 104 E 104
Cdd:COG4783 139 D 139
p23_CacyBP cd06468
p23_like domain found in proteins similar to Calcyclin-Binding Protein(CacyBP) ...
 159-239 9.13e-08

p23_like domain found in proteins similar to Calcyclin-Binding Protein(CacyBP)/Siah-1-interacting protein (SIP). CacyBP/SIP interacts with S100A6 (calcyclin), with some other members of the S100 family, with tubulin, and with Siah-1 and Skp-1. The latter two are components of the ubiquitin ligase that regulates beta-catenin degradation. The beta-catenin gene is an oncogene participating in tumorigenesis in many different cancers. Overexpression of CacyBP/SIP, in part through its effect on the expression of beta-catenin, inhibits the proliferation, tumorigenicity, and invasion of gastric cancer cells. CacyBP/SIP is abundant in neurons and neuroblastoma NB2a cells. An extensive re-organization of microtubules accompanies the differentiation of NB2a cells. CacyBP/SIP may contribute to NB2a cell differentiation through binding to and increasing the oligomerization of tubulin. CacyBP/SIP is also implicated in differentiation of erythroid cells, rat neonatal cardiomyocytes, in mouse endometrial events, and in thymocyte development.


Pssm-ID: 107225  Cd Length: 92  Bit Score: 49.18  E-value: 9.13e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237 159 QKPEEVVVTVFAKGI---PKQNVNIDFGEQILSV-VIEVPGEDAYYLQPRLFGKIIPDKCKYEVLSTKIEICLAKADIIT 234
Cdd:cd06468   8 QSDKFVKIYITLKGVhqlPKENIQVEFTERSFELkVHDLNGKNYRFTINRLLKKIDPEKSSFKVKTDRIVITLAKKKEKK 87


                ....*
gi 79325237 235 WASLE 239
Cdd:cd06468  88 WESLT 92
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
31-103 1.46e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.45  E-value: 1.46e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 79325237  31 LDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPS 103
Cdd:COG4785  68 ALPDLAQLYYERGVAYDSLGDY-DLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 24-112 4.06e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.88  E-value: 4.06e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPS 103
Cdd:COG2956 166 ALEKALKLDPDCARALLLLAELYLEQGDY-EEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244


                ....*....
gi 79325237 104 ESKFKKLID 112
Cdd:COG2956 245 DDLLLALAD 253
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 27-104 1.40e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 1.40e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 79325237  27 KAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPSE 104
Cdd:COG4235   8 QALAANPNDAEGWLLLGRAYLRLGRY-DEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDN 84
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 35-105 5.52e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.49  E-value: 5.52e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 79325237  35 CAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPSES 105
Cdd:COG4783   3 CAEALYALAQALLLAGDY-DEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP 72
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1-103 5.84e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.33  E-value: 5.84e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237   1 MAKELADKAKEafvdddfdvavdLYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTA 80
Cdd:COG2956  87 LKAGLLDRAEE------------LLEKLLELDPDDAEALRLLAEIYEQEGDW-EKAIEVLERLLKLGPENAHAYCELAEL 153

                        90       100
                ....*....|....*....|...
gi 79325237  81 CMKLEEYRTAKTALEKGASITPS 103
Cdd:COG2956 154 YLEQGDYDEAIEALEKALKLDPD 176
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 2-105 9.82e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.25  E-value: 9.82e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237   2 AKELADKAKEAFVDDDFDVAVDLYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTAC 81
Cdd:COG5010  20 LRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDF-EESLALLEQALQLDPNNPELYYNLALLY 98

                        90       100
                ....*....|....*....|....
gi 79325237  82 MKLEEYRTAKTALEKGASITPSES 105
Cdd:COG5010  99 SRSGDKDEAKEYYEKALALSPDNP 122
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 2-90 4.46e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 41.89  E-value: 4.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237     2 AKELADKAKEAFVDDDFDVAVDLYSKAIDLDPNCAeFFADRAQAYIKLESFTaEAVADANKAIELDPSLTKAYLRKGTAC 81
Cdd:TIGR00990 127 AAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPDPV-YYSNRAACHNALGDWE-KVVEDTTAALELDPDYSKALNRRANAY 204


                  ....*....
gi 79325237    82 MKLEEYRTA 90
Cdd:TIGR00990 205 DGLGKYADA 213
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 24-74 5.40e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.90  E-value: 5.40e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAY 74
Cdd:COG3914 168 ALRRALELDPDNAEALNNLGNALQDLGRL-EEAIAAYRRALELDPDNADAH 217
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
25-75 6.12e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.67  E-value: 6.12e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 79325237  25 YSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYL 75
Cdd:COG4785 130 FDRALELDPDYAYAYLNRGIALYYLGRY-ELAIADLEKALELDPNDPERAL 179
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 24-107 1.12e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.10  E-value: 1.12e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79325237  24 LYSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSLTKAYLRKGTACMKLEEYRTAKTALEKGASITPS 103
Cdd:COG2956  64 IHQKLLERDPDRAEALLELAQDYLKAGLL-DRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPE 142


                ....
gi 79325237 104 ESKF 107
Cdd:COG2956 143 NAHA 146
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
25-70 4.07e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.30  E-value: 4.07e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 79325237  25 YSKAIDLDPNCAEFFADRAQAYIKLESFtAEAVADANKAIELDPSL 70
Cdd:COG3063  48 LEKALKLDPNNAEALLNLAELLLELGDY-DEALAYLERALELDPSA 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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