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Conserved domains on  [gi|110347431|ref|NP_001036009|]
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latent-transforming growth factor beta-binding protein 4 isoform a precursor [Homo sapiens]

Protein Classification

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List of domain hits

 Name Accession Description Interval E-value
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 418-459 4.96e-11

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


:

Pssm-ID: 459903  Cd Length: 44  Bit Score: 58.83  E-value: 4.96e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 110347431   418 CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREIC 459
Cdd:pfam00683    3 CSNPLPGNVTKSECCCTSVGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1360-1402 2.26e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


:

Pssm-ID: 459903  Cd Length: 44  Bit Score: 48.81  E-value: 2.26e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347431  1360 VCSHPrLDRQATYTECCCLY-GEAWGMDCALCPAQDSDDFEALC 1402
Cdd:pfam00683    2 RCSNP-LPGNVTKSECCCTSvGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1193-1235 6.40e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


:

Pssm-ID: 459903  Cd Length: 44  Bit Score: 47.27  E-value: 6.40e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347431  1193 CDNILARNVTWQECCC-TVGEGWGSGCriQQCPGTETAEYQSLC 1235
Cdd:pfam00683    3 CSNPLPGNVTKSECCCtSVGRAWGSPC--ELCPPPGTDEFRELC 44
EGF_CA smart00179
Calcium-binding EGF-like domain;
878-914 1.11e-06

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.47  E-value: 1.11e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347431    878 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 914
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA smart00179
Calcium-binding EGF-like domain;
834-867 1.45e-06

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.09  E-value: 1.45e-06
                            10        20        30
                    ....*....|....*....|....*....|....
gi 110347431    834 DVDECSSGaPPCGPHGHCTNTEGSFRCSCAPGYR 867
Cdd:smart00179    1 DIDECASG-NPCQNGGTCVNTVGSYRCECPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
1049-1090 1.72e-06

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.09  E-value: 1.72e-06
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347431   1049 DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEgarDGRHCV 1090
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYT---DGRNCE 39
EGF_CA smart00179
Calcium-binding EGF-like domain;
920-955 8.33e-06

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 44.16  E-value: 8.33e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347431    920 DVDECSEEDLCQSG-ICTNTDGSFECICPPGHRAGPD 955
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 671-708 2.44e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


:

Pssm-ID: 238011  Cd Length: 38  Bit Score: 42.62  E-value: 2.44e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 110347431  671 DVDECtQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE 708
Cdd:cd00054     1 DIDEC-ASGNPCQNGGtCVNTVGSYRCSCPPGYTGRNCE 38
EGF_CA smart00179
Calcium-binding EGF-like domain;
357-387 3.52e-05

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 42.23  E-value: 3.52e-05
                            10        20        30
                    ....*....|....*....|....*....|..
gi 110347431    357 DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 387
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGY 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
752-793 1.63e-04

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 40.31  E-value: 1.63e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|...
gi 110347431    752 DVDECArSPPPCTYG-RCENTEGSFQCVCPMGFqpnTAGSECE 793
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGY---TDGRNCE 39
EGF_CA smart00179
Calcium-binding EGF-like domain;
587-623 3.06e-04

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 39.54  E-value: 3.06e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 110347431    587 DVDECRRvPPPCAPG-RCENSPGSFRCVCGPGFRAGPR 623
Cdd:smart00179    1 DIDECAS-GNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA smart00179
Calcium-binding EGF-like domain;
629-670 6.04e-04

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 38.77  E-value: 6.04e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347431    629 DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAaphGASCQ 670
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTD---GRNCE 39
EGF_CA smart00179
Calcium-binding EGF-like domain;
710-744 1.26e-03

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 38.00  E-value: 1.26e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347431    710 DVDECAqEPPPCGPG-RCDNTAGSFHCACPAGFRSR 744
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGYTDG 35
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1296-1325 2.22e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


:

Pssm-ID: 238011  Cd Length: 38  Bit Score: 37.23  E-value: 2.22e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 110347431 1296 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPP 30
EGF_CA smart00179
Calcium-binding EGF-like domain;
1574-1608 2.78e-03

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.84  E-value: 2.78e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347431   1574 DINECDEaeaaSPLCVN-ARCLNTDGSFRCICRPGF 1608
Cdd:smart00179    1 DIDECAS----GNPCQNgGTCVNTVGSYRCECPPGY 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
961-999 3.84e-03

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.46  E-value: 3.84e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 110347431    961 DVDECRERGPALCGSqRCENSPGSYRCvrDCDPGYHAGP 999
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRC--ECPPGYTDGR 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
1005-1048 4.37e-03

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.46  E-value: 4.37e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....
gi 110347431   1005 DVDECQEYGPEICGAqRCENTPGSYRCTpaCDPGYqpTPGGGCQ 1048
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRCE--CPPGY--TDGRNCE 39
 
Name Accession Description Interval E-value
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 418-459 4.96e-11

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 58.83  E-value: 4.96e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 110347431   418 CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREIC 459
Cdd:pfam00683    3 CSNPLPGNVTKSECCCTSVGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1360-1402 2.26e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 48.81  E-value: 2.26e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347431  1360 VCSHPrLDRQATYTECCCLY-GEAWGMDCALCPAQDSDDFEALC 1402
Cdd:pfam00683    2 RCSNP-LPGNVTKSECCCTSvGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1193-1235 6.40e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 47.27  E-value: 6.40e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347431  1193 CDNILARNVTWQECCC-TVGEGWGSGCriQQCPGTETAEYQSLC 1235
Cdd:pfam00683    3 CSNPLPGNVTKSECCCtSVGRAWGSPC--ELCPPPGTDEFRELC 44
EGF_CA smart00179
Calcium-binding EGF-like domain;
878-914 1.11e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.47  E-value: 1.11e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347431    878 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 914
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA smart00179
Calcium-binding EGF-like domain;
834-867 1.45e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.09  E-value: 1.45e-06
                            10        20        30
                    ....*....|....*....|....*....|....
gi 110347431    834 DVDECSSGaPPCGPHGHCTNTEGSFRCSCAPGYR 867
Cdd:smart00179    1 DIDECASG-NPCQNGGTCVNTVGSYRCECPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
1049-1090 1.72e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.09  E-value: 1.72e-06
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347431   1049 DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEgarDGRHCV 1090
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYT---DGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 834-867 2.31e-06

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 45.71  E-value: 2.31e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 110347431  834 DVDECSSGaPPCGPHGHCTNTEGSFRCSCAPGYR 867
Cdd:cd00054     1 DIDECASG-NPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1049-1084 6.48e-06

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 44.55  E-value: 6.48e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347431 1049 DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR 1084
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
920-955 8.33e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 44.16  E-value: 8.33e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347431    920 DVDECSEEDLCQSG-ICTNTDGSFECICPPGHRAGPD 955
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 878-910 1.83e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 43.01  E-value: 1.83e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347431  878 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYR 910
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 671-708 2.44e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 42.62  E-value: 2.44e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 110347431  671 DVDECtQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE 708
Cdd:cd00054     1 DIDEC-ASGNPCQNGGtCVNTVGSYRCSCPPGYTGRNCE 38
EGF_CA pfam07645
Calcium-binding EGF domain;
834-865 3.46e-05

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 42.22  E-value: 3.46e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347431   834 DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPG 865
Cdd:pfam07645    1 DVDECATGTHNCPANTVCVNTIGSFECRCPDG 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
357-387 3.52e-05

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 42.23  E-value: 3.52e-05
                            10        20        30
                    ....*....|....*....|....*....|..
gi 110347431    357 DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 387
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGY 32
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 920-951 7.54e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 41.47  E-value: 7.54e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347431  920 DVDECSEEDLCQ-SGICTNTDGSFECICPPGHR 951
Cdd:cd00054     1 DIDECASGNPCQnGGTCVNTVGSYRCSCPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
671-708 1.09e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 41.08  E-value: 1.09e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 110347431    671 DVDECtQSPGLCGRGA-CKNLPGSFRCVCPAGFR-GSACE 708
Cdd:smart00179    1 DIDEC-ASGNPCQNGGtCVNTVGSYRCECPPGYTdGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 357-391 1.37e-04

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 40.70  E-value: 1.37e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347431  357 DVDECATGGRCQ-HGECANTRGGYTCVCPDGFLLDS 391
Cdd:cd00054     1 DIDECASGNPCQnGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
752-793 1.63e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 40.31  E-value: 1.63e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|...
gi 110347431    752 DVDECArSPPPCTYG-RCENTEGSFQCVCPMGFqpnTAGSECE 793
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGY---TDGRNCE 39
EGF_CA smart00179
Calcium-binding EGF-like domain;
587-623 3.06e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 39.54  E-value: 3.06e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 110347431    587 DVDECRRvPPPCAPG-RCENSPGSFRCVCGPGFRAGPR 623
Cdd:smart00179    1 DIDECAS-GNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA smart00179
Calcium-binding EGF-like domain;
629-670 6.04e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 38.77  E-value: 6.04e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347431    629 DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAaphGASCQ 670
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTD---GRNCE 39
EGF_CA pfam07645
Calcium-binding EGF domain;
920-949 9.56e-04

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 37.99  E-value: 9.56e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347431   920 DVDEC-SEEDLC-QSGICTNTDGSFECICPPG 949
Cdd:pfam07645    1 DVDECaTGTHNCpANTVCVNTIGSFECRCPDG 32
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 1059-1089 1.19e-03

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 37.96  E-value: 1.19e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 110347431  1059 CGAHAVCQNLPGSFQCLCDQGYEGarDGRHC 1089
Cdd:pfam12947    8 CHPNATCTNTGGSFTCTCNDGYTG--DGVTC 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
710-744 1.26e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 38.00  E-value: 1.26e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347431    710 DVDECAqEPPPCGPG-RCDNTAGSFHCACPAGFRSR 744
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGYTDG 35
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 752-787 1.31e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 38.00  E-value: 1.31e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347431  752 DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 787
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 710-744 1.39e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 37.62  E-value: 1.39e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 110347431  710 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 744
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGR 35
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1296-1325 2.22e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 37.23  E-value: 2.22e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 110347431 1296 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPP 30
EGF_CA smart00179
Calcium-binding EGF-like domain;
1296-1325 2.42e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 37.23  E-value: 2.42e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 110347431   1296 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPP 30
EGF_CA pfam07645
Calcium-binding EGF domain;
357-386 2.53e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 36.83  E-value: 2.53e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347431   357 DVDECATGGR-CQHGE-CANTRGGYTCVCPDG 386
Cdd:pfam07645    1 DVDECATGTHnCPANTvCVNTIGSFECRCPDG 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
1574-1608 2.78e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.84  E-value: 2.78e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347431   1574 DINECDEaeaaSPLCVN-ARCLNTDGSFRCICRPGF 1608
Cdd:smart00179    1 DIDECAS----GNPCQNgGTCVNTVGSYRCECPPGY 32
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 587-619 3.63e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.46  E-value: 3.63e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347431  587 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFR 619
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 629-670 3.67e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.46  E-value: 3.67e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 110347431  629 DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYqaapHGASCQ 670
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGY----TGRNCE 38
EGF_CA smart00179
Calcium-binding EGF-like domain;
961-999 3.84e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.46  E-value: 3.84e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 110347431    961 DVDECRERGPALCGSqRCENSPGSYRCvrDCDPGYHAGP 999
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRC--ECPPGYTDGR 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
1005-1048 4.37e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.46  E-value: 4.37e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....
gi 110347431   1005 DVDECQEYGPEICGAqRCENTPGSYRCTpaCDPGYqpTPGGGCQ 1048
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRCE--CPPGY--TDGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1574-1612 6.01e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.08  E-value: 6.01e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 110347431 1574 DINECDEAeaaSPLCVNARCLNTDGSFRCICRPGFAPTH 1612
Cdd:cd00054     1 DIDECASG---NPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA pfam07645
Calcium-binding EGF domain;
752-782 8.25e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 35.29  E-value: 8.25e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347431   752 DVDECARSPPPCTY-GRCENTEGSFQCVCPMG 782
Cdd:pfam07645    1 DVDECATGTHNCPAnTVCVNTIGSFECRCPDG 32
 
Name Accession Description Interval E-value
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 418-459 4.96e-11

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 58.83  E-value: 4.96e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 110347431   418 CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREIC 459
Cdd:pfam00683    3 CSNPLPGNVTKSECCCTSVGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1360-1402 2.26e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 48.81  E-value: 2.26e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347431  1360 VCSHPrLDRQATYTECCCLY-GEAWGMDCALCPAQDSDDFEALC 1402
Cdd:pfam00683    2 RCSNP-LPGNVTKSECCCTSvGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1193-1235 6.40e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 47.27  E-value: 6.40e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347431  1193 CDNILARNVTWQECCC-TVGEGWGSGCriQQCPGTETAEYQSLC 1235
Cdd:pfam00683    3 CSNPLPGNVTKSECCCtSVGRAWGSPC--ELCPPPGTDEFRELC 44
EGF_CA smart00179
Calcium-binding EGF-like domain;
878-914 1.11e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.47  E-value: 1.11e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347431    878 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 914
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA smart00179
Calcium-binding EGF-like domain;
834-867 1.45e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.09  E-value: 1.45e-06
                            10        20        30
                    ....*....|....*....|....*....|....
gi 110347431    834 DVDECSSGaPPCGPHGHCTNTEGSFRCSCAPGYR 867
Cdd:smart00179    1 DIDECASG-NPCQNGGTCVNTVGSYRCECPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
1049-1090 1.72e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.09  E-value: 1.72e-06
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347431   1049 DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEgarDGRHCV 1090
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYT---DGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 834-867 2.31e-06

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 45.71  E-value: 2.31e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 110347431  834 DVDECSSGaPPCGPHGHCTNTEGSFRCSCAPGYR 867
Cdd:cd00054     1 DIDECASG-NPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1049-1084 6.48e-06

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 44.55  E-value: 6.48e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347431 1049 DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR 1084
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
920-955 8.33e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 44.16  E-value: 8.33e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347431    920 DVDECSEEDLCQSG-ICTNTDGSFECICPPGHRAGPD 955
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 878-910 1.83e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 43.01  E-value: 1.83e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347431  878 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYR 910
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 671-708 2.44e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 42.62  E-value: 2.44e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 110347431  671 DVDECtQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE 708
Cdd:cd00054     1 DIDEC-ASGNPCQNGGtCVNTVGSYRCSCPPGYTGRNCE 38
EGF_CA pfam07645
Calcium-binding EGF domain;
834-865 3.46e-05

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 42.22  E-value: 3.46e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347431   834 DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPG 865
Cdd:pfam07645    1 DVDECATGTHNCPANTVCVNTIGSFECRCPDG 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
357-387 3.52e-05

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 42.23  E-value: 3.52e-05
                            10        20        30
                    ....*....|....*....|....*....|..
gi 110347431    357 DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 387
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGY 32
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 920-951 7.54e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 41.47  E-value: 7.54e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347431  920 DVDECSEEDLCQ-SGICTNTDGSFECICPPGHR 951
Cdd:cd00054     1 DIDECASGNPCQnGGTCVNTVGSYRCSCPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
671-708 1.09e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 41.08  E-value: 1.09e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 110347431    671 DVDECtQSPGLCGRGA-CKNLPGSFRCVCPAGFR-GSACE 708
Cdd:smart00179    1 DIDEC-ASGNPCQNGGtCVNTVGSYRCECPPGYTdGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 357-391 1.37e-04

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 40.70  E-value: 1.37e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347431  357 DVDECATGGRCQ-HGECANTRGGYTCVCPDGFLLDS 391
Cdd:cd00054     1 DIDECASGNPCQnGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
752-793 1.63e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 40.31  E-value: 1.63e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|...
gi 110347431    752 DVDECArSPPPCTYG-RCENTEGSFQCVCPMGFqpnTAGSECE 793
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGY---TDGRNCE 39
EGF_CA smart00179
Calcium-binding EGF-like domain;
587-623 3.06e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 39.54  E-value: 3.06e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 110347431    587 DVDECRRvPPPCAPG-RCENSPGSFRCVCGPGFRAGPR 623
Cdd:smart00179    1 DIDECAS-GNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 838-867 3.34e-04

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 39.50  E-value: 3.34e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 110347431   838 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYR 867
Cdd:pfam12947    1 CSDNNGGCHPNATCTNTGGSFTCTCNDGYT 30
EGF_CA smart00179
Calcium-binding EGF-like domain;
629-670 6.04e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 38.77  E-value: 6.04e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347431    629 DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAaphGASCQ 670
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTD---GRNCE 39
EGF_CA pfam07645
Calcium-binding EGF domain;
920-949 9.56e-04

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 37.99  E-value: 9.56e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347431   920 DVDEC-SEEDLC-QSGICTNTDGSFECICPPG 949
Cdd:pfam07645    1 DVDECaTGTHNCpANTVCVNTIGSFECRCPDG 32
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 1059-1089 1.19e-03

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 37.96  E-value: 1.19e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 110347431  1059 CGAHAVCQNLPGSFQCLCDQGYEGarDGRHC 1089
Cdd:pfam12947    8 CHPNATCTNTGGSFTCTCNDGYTG--DGVTC 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
710-744 1.26e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 38.00  E-value: 1.26e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347431    710 DVDECAqEPPPCGPG-RCDNTAGSFHCACPAGFRSR 744
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGYTDG 35
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 752-787 1.31e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 38.00  E-value: 1.31e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347431  752 DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 787
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 710-744 1.39e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 37.62  E-value: 1.39e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 110347431  710 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 744
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGR 35
EGF smart00181
Epidermal growth factor-like domain;
360-392 1.86e-03

Epidermal growth factor-like domain;


Pssm-ID: 214544  Cd Length: 35  Bit Score: 37.50  E-value: 1.86e-03
                            10        20        30
                    ....*....|....*....|....*....|...
gi 110347431    360 ECATGGRCQHGECANTRGGYTCVCPDGFLLDSS 392
Cdd:smart00181    1 ECASGGPCSNGTCINTPGSYTCSCPPGYTGDKR 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1296-1325 2.22e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 37.23  E-value: 2.22e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 110347431 1296 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPP 30
EGF_CA smart00179
Calcium-binding EGF-like domain;
1296-1325 2.42e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 37.23  E-value: 2.42e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 110347431   1296 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPP 30
EGF_CA pfam07645
Calcium-binding EGF domain;
357-386 2.53e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 36.83  E-value: 2.53e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347431   357 DVDECATGGR-CQHGE-CANTRGGYTCVCPDG 386
Cdd:pfam07645    1 DVDECATGTHnCPANTvCVNTIGSFECRCPDG 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
1574-1608 2.78e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.84  E-value: 2.78e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347431   1574 DINECDEaeaaSPLCVN-ARCLNTDGSFRCICRPGF 1608
Cdd:smart00179    1 DIDECAS----GNPCQNgGTCVNTVGSYRCECPPGY 32
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 587-619 3.63e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.46  E-value: 3.63e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347431  587 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFR 619
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 629-670 3.67e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.46  E-value: 3.67e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 110347431  629 DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYqaapHGASCQ 670
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGY----TGRNCE 38
EGF_CA smart00179
Calcium-binding EGF-like domain;
961-999 3.84e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.46  E-value: 3.84e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 110347431    961 DVDECRERGPALCGSqRCENSPGSYRCvrDCDPGYHAGP 999
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRC--ECPPGYTDGR 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
1005-1048 4.37e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.46  E-value: 4.37e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....
gi 110347431   1005 DVDECQEYGPEICGAqRCENTPGSYRCTpaCDPGYqpTPGGGCQ 1048
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRCE--CPPGY--TDGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1574-1612 6.01e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.08  E-value: 6.01e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 110347431 1574 DINECDEAeaaSPLCVNARCLNTDGSFRCICRPGFAPTH 1612
Cdd:cd00054     1 DIDECASG---NPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA pfam07645
Calcium-binding EGF domain;
752-782 8.25e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 35.29  E-value: 8.25e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347431   752 DVDECARSPPPCTY-GRCENTEGSFQCVCPMG 782
Cdd:pfam07645    1 DVDECATGTHNCPAnTVCVNTIGSFECRCPDG 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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