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Conserved domains on  [gi|145332915|ref|NP_001078323|]
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plasma membrane intrinsic protein 1A [Arabidopsis thaliana]

Protein Classification

MIP/aquaporin family protein( domain architecture ID 11088534)

MIP (Major Intrinsic Protein)/aquaporin family protein similar to aquaporin that permits osmotically driven movement of water in both directions, and glycerol uptake facilitator protein that mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism

CATH:  1.20.1080.10
Gene Ontology:  GO:0055085|GO:0015267
PubMed:  11473620|8849412|11964478
SCOP:  3000508
TCDB:  1.A.8

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 44-273 5.56e-101

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


:

Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 294.61  E-value: 5.56e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915   44 ELSSWSFWRAGIAEFIATFLFLYITVLTVMGVKRSPNMCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFL 123
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  124 ARKLSLTRALYYIVMQCLGAICGAGVVKGFQPKqYQALGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRNAR 203
Cdd:pfam00230  81 GRRFSLLRAIFYIVAQLLGAIAGAALLYGVTVG-LQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  204 DSHVpilAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdhsWDDHWVFWVGPFIGAALAALYH 273
Cdd:pfam00230 160 LGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
 
Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 44-273 5.56e-101

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 294.61  E-value: 5.56e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915   44 ELSSWSFWRAGIAEFIATFLFLYITVLTVMGVKRSPNMCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFL 123
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  124 ARKLSLTRALYYIVMQCLGAICGAGVVKGFQPKqYQALGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRNAR 203
Cdd:pfam00230  81 GRRFSLLRAIFYIVAQLLGAIAGAALLYGVTVG-LQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  204 DSHVpilAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdhsWDDHWVFWVGPFIGAALAALYH 273
Cdd:pfam00230 160 LGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 52-276 9.65e-81

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 243.31  E-value: 9.65e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  52 RAGIAEFIATFLFLYITVLTVMGVKRSPNmcASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTR 131
Cdd:cd00333    1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGG--ASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 132 ALYYIVMQCLGAICGAGVVKGFQPKQYQALGGGANTVAH--------GYTKGSGLGAEIIGTFVLVYTVFSATDAKRNAr 203
Cdd:cd00333   79 VIPYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGifgtypspGVSNGNAFFVEFIGTFILVLVVFATTDDPNGP- 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 145332915 204 dsHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKDHSWDDHWVFWVGPFIGAALAALYHVVV 276
Cdd:cd00333  158 --PPGGLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLARHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 56-273 6.75e-71

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 217.94  E-value: 6.75e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915   56 AEFIATFLFLYITVLTVMGVKRsPNMCASVGIQ---GIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRA 132
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALGVNV-AGAYGAVGGGqflGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  133 LYYIVMQCLGAICGAGVVKGFQPKQYQALGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDaKRNARDSHvpILAP 212
Cdd:TIGR00861  80 PVYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTD-DRNRVPRG--GFAP 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 145332915  213 LPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdHSWDDHWVFWVGPFIGAALAALYH 273
Cdd:TIGR00861 157 LAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGL-AGWGNHWVYWVGPIIGAILGALVY 216
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 49-271 2.88e-59

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 188.41  E-value: 2.88e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  49 SFWRAGIAEFIATFLFLYITVLTVMGVKRSPnmcASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLS 128
Cdd:COG0580    1 SLMKRLLAEFLGTFILVLLGCGVVAVLAGTK---GGIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 129 LTRALYYIVMQCLGAICGAGVVKGFQPKQYQALGGGANTV-------AHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRN 201
Cdd:COG0580   78 WKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATEDGGAKLgvfatspAIGYSLGAAFLTEIIGTFVLVFVILGITDKRAA 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 145332915 202 ARDshvpiLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIY--NKDHS-WDDHWVFWVGPFIGAALAAL 271
Cdd:COG0580  158 PGG-----LAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHalGKGGSdWGYLWVPIVAPILGAALAAL 225
PRK05420 PRK05420
aquaporin Z; Provisional
 55-275 1.76e-32

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 119.30  E-value: 1.76e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  55 IAEFIATFLFlyitvltVMGVKRSPNMCAS-----VGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSL 129
Cdd:PRK05420   6 AAEFFGTFWL-------VFGGCGSAVLAAAfpelgIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 130 TRALYYIVMQCLGAICGAGVV--------------KGFQPKQYQALGGGantvahGYTKGSGLGAEIIGTFVLVYTVFSA 195
Cdd:PRK05420  79 KELVPYIIAQVVGGIAAAAVLyliasgkagfdlagSGFASNGYGEHSPG------GYSLLAALVCEVVLTAFFLLVILGA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 196 TDAKRNARdshvpiLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAiIYNKDHSWDDHWVFWVGPFIGAALAAL-YHV 274
Cdd:PRK05420 153 TDKRAPAG------FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVA-LFVGGWALEQLWLFWVAPIVGAIIGGLiYRL 225


                 .
gi 145332915 275 V 275
Cdd:PRK05420 226 L 226
 
Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 44-273 5.56e-101

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 294.61  E-value: 5.56e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915   44 ELSSWSFWRAGIAEFIATFLFLYITVLTVMGVKRSPNMCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFL 123
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  124 ARKLSLTRALYYIVMQCLGAICGAGVVKGFQPKqYQALGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRNAR 203
Cdd:pfam00230  81 GRRFSLLRAIFYIVAQLLGAIAGAALLYGVTVG-LQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  204 DSHVpilAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdhsWDDHWVFWVGPFIGAALAALYH 273
Cdd:pfam00230 160 LGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 52-276 9.65e-81

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 243.31  E-value: 9.65e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  52 RAGIAEFIATFLFLYITVLTVMGVKRSPNmcASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTR 131
Cdd:cd00333    1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGG--ASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 132 ALYYIVMQCLGAICGAGVVKGFQPKQYQALGGGANTVAH--------GYTKGSGLGAEIIGTFVLVYTVFSATDAKRNAr 203
Cdd:cd00333   79 VIPYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGifgtypspGVSNGNAFFVEFIGTFILVLVVFATTDDPNGP- 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 145332915 204 dsHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKDHSWDDHWVFWVGPFIGAALAALYHVVV 276
Cdd:cd00333  158 --PPGGLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLARHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 56-273 6.75e-71

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 217.94  E-value: 6.75e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915   56 AEFIATFLFLYITVLTVMGVKRsPNMCASVGIQ---GIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRA 132
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALGVNV-AGAYGAVGGGqflGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  133 LYYIVMQCLGAICGAGVVKGFQPKQYQALGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDaKRNARDSHvpILAP 212
Cdd:TIGR00861  80 PVYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTD-DRNRVPRG--GFAP 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 145332915  213 LPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdHSWDDHWVFWVGPFIGAALAALYH 273
Cdd:TIGR00861 157 LAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGL-AGWGNHWVYWVGPIIGAILGALVY 216
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 49-271 2.88e-59

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 188.41  E-value: 2.88e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  49 SFWRAGIAEFIATFLFLYITVLTVMGVKRSPnmcASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLS 128
Cdd:COG0580    1 SLMKRLLAEFLGTFILVLLGCGVVAVLAGTK---GGIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 129 LTRALYYIVMQCLGAICGAGVVKGFQPKQYQALGGGANTV-------AHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRN 201
Cdd:COG0580   78 WKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATEDGGAKLgvfatspAIGYSLGAAFLTEIIGTFVLVFVILGITDKRAA 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 145332915 202 ARDshvpiLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIY--NKDHS-WDDHWVFWVGPFIGAALAAL 271
Cdd:COG0580  158 PGG-----LAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHalGKGGSdWGYLWVPIVAPILGAALAAL 225
PRK05420 PRK05420
aquaporin Z; Provisional
 55-275 1.76e-32

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 119.30  E-value: 1.76e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  55 IAEFIATFLFlyitvltVMGVKRSPNMCAS-----VGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSL 129
Cdd:PRK05420   6 AAEFFGTFWL-------VFGGCGSAVLAAAfpelgIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 130 TRALYYIVMQCLGAICGAGVV--------------KGFQPKQYQALGGGantvahGYTKGSGLGAEIIGTFVLVYTVFSA 195
Cdd:PRK05420  79 KELVPYIIAQVVGGIAAAAVLyliasgkagfdlagSGFASNGYGEHSPG------GYSLLAALVCEVVLTAFFLLVILGA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 196 TDAKRNARdshvpiLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAiIYNKDHSWDDHWVFWVGPFIGAALAAL-YHV 274
Cdd:PRK05420 153 TDKRAPAG------FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVA-LFVGGWALEQLWLFWVAPIVGAIIGGLiYRL 225


                 .
gi 145332915 275 V 275
Cdd:PRK05420 226 L 226
PLN00027 PLN00027
aquaporin TIP; Provisional
 52-277 3.68e-32

aquaporin TIP; Provisional


Pssm-ID: 177664  Cd Length: 252  Bit Score: 119.12  E-value: 3.68e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  52 RAGIAEFIATFLFLYITVLTVMGVKRSPNMCASV--GIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSL 129
Cdd:PLN00027  21 KAALAEFISTLIFVFAGEGSGMAFNKLTDNGSTTpaGLVAAALAHAFALFVAVSVGANISGGHVNPAVTFGAFIGGNITL 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 130 TRALYYIVMQCLGAICGAGVVKgfqpkqyqALGGGANTVAHGYTKGSG----LGAEIIGTFVLVYTVF-SATDAKRnard 204
Cdd:PLN00027 101 LRGILYWIAQLLGSVVACLLLK--------FSTGGLETSAFSLSSGVGvwnaFVFEIVMTFGLVYTVYaTAVDPKK---- 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 145332915 205 SHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIynkDHSWDDHWVFWVGPFIGAALAAL-YHVVVI 277
Cdd:PLN00027 169 GDLGIIAPIAIGFIVGANILAGGAFDGASMNPAVSFGPAVV---SWTWTNHWVYWAGPLIGGGIAGLvYELIFI 239
PLN00166 PLN00166
aquaporin TIP2; Provisional
 43-273 3.71e-31

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 116.57  E-value: 3.71e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  43 GELSSWSFWRAGIAEFIATFLFLYITVLTVMGVKRSPNMCA--SVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFG 120
Cdd:PLN00166  10 GDSFSVASLKAYLSEFIATLLFVFAGVGSAIAFAKLTSDAAldPAGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTLG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 121 LFLARKLSLTRALYYIVMQCLGAICGAGVVKGFQPKQYQALGGgantVAHGYTKGSGLGAEIIGTFVLVYTVF-SATDAK 199
Cdd:PLN00166  90 LAIGGNITIITGFFYWIAQCLGSIVACLLLVFVTNGESVPTHG----VAAGLGAIEGVVMEIVVTFALVYTVYaTAADPK 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 145332915 200 RNArdshVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNkdhSWDDHWVFWVGPFIGAALAALYH 273
Cdd:PLN00166 166 KGS----LGTIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVVSG---DFSQIWIYWVGPLVGGALAGLIY 232
PLN00167 PLN00167
aquaporin TIP5; Provisional
 52-277 3.09e-29

aquaporin TIP5; Provisional


Pssm-ID: 215085  Cd Length: 256  Bit Score: 111.53  E-value: 3.09e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  52 RAGIAEFIATFLFLYITVLTVMGVKR-SPNMCA---SVGIQGIAWAFGgmIFALVYCTAGISGGHINPAVTFGLFLARKL 127
Cdd:PLN00167  23 RSYLAEFISTFFFVFAAVGSAMSSRKlMPDAASdpsSLLIVAIANAFA--LSSAVYIAANISGGHVNPAVTFGMAVGGHI 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 128 SLTRALYYIVMQCLGAICGAGVVKGFQPKQYQALgggaNTVAHGYTkgsGLGAEIIG---TFVLVYTVFSATDAKRNARD 204
Cdd:PLN00167 101 SVPTAMFYWISQMLASVMACLFLKVTTVGQHVPT----YKIAEEMT---GFGASVLEgvlTFGLVYTVYAAGDPRRGLLG 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 145332915 205 ShvpiLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKdhsWDDHWVFWVGPFIGAALAALYHVVVI 277
Cdd:PLN00167 174 A----IGPLAIGLVAGANVLAAGPFSGGSMNPACAFGSAVVAGS---FKNQAVYWVGPLLGGAVAGLLYDNVV 239
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
 51-277 5.16e-19

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 84.79  E-value: 5.16e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  51 WRAGIAEFIATFLFLYITVLTVMGVKRSPNMCASVGIQgIAWAFGgmIFALVYCTAGISGGHINPAVTFGLFLARKLSLT 130
Cdd:PTZ00016  50 VREYVAEFLGTFVLLFFGEGVVATTHTVGNNGDYLAIT-IGWGLG--VTFGLLVSAGISGGHLNPAVTLGNAVFGKFPWK 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 131 RALYYIVMQCLGAICGAGVVKGFQPKQYQALGGGANTVAHGYTKGSGLGA-------------EIIGTFVLVYTVFSATD 197
Cdd:PTZ00016 127 KLPGYFVAQLLGAFVGAACVYGLYYGFFKDHGIPELPWETMANGFAGVFAtypregnfyaifsELILTAILLLVILAITD 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 198 AKRNARDSHVpilaPLPIGFAVFLVHLATIPITGTGINPARSLGA----AIIYNKDHSWDDHWVFW---VGPFIGAALAA 270
Cdd:PTZ00016 207 PNNCPAFNYL----PVAVGLLVFVIGISFGGNTGYALNPARDLGPrlfsAILWGSEVFTKDNYYFWvplVAPFVGAVLGM 282


                 ....*..
gi 145332915 271 LYHVVVI 277
Cdd:PTZ00016 283 FLYDKFI 289
PLN00183 PLN00183
putative aquaporin NIP7; Provisional
 52-281 6.04e-19

putative aquaporin NIP7; Provisional


Pssm-ID: 215092  Cd Length: 274  Bit Score: 84.14  E-value: 6.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  52 RAGIAEFIATFLFLYitvlTVMGVKRSPN-MCASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLT 130
Cdd:PLN00183  46 RMVLAEMVGTFILMF----CVCGIIASTQlSGGEVGLLEYAATAGLTVVVVVFSIGSISGAHVNPSVTIAFATFGHFPWS 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 131 RALYYIVMQCLGAICGAGVVKgfqpkqyQALGGGANTVAHGYTKG--SGLGAEIIGTFVLVYTVFSATDAKRNARDshvp 208
Cdd:PLN00183 122 KVPLYITAQTVGSVLATYVGV-------SVYGVKADLMTTKPAQGcsSAFWVEFIATFIVMFLAASLTSQPQSLGH---- 190

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 145332915 209 iLAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIynkdhSWD--DHWVFWVGPFIGAALAAL-YHVVVIRAIP 281
Cdd:PLN00183 191 -LSGFVIGIAIGLAVLITGPVSGGSMNPARSLGPAIV-----SWDfkDIWIYITAPTIGAVAGALmFHLLRLRTQP 260
PLN00184 PLN00184
aquaporin NIP1; Provisional
 47-275 1.33e-18

aquaporin NIP1; Provisional


Pssm-ID: 177778  Cd Length: 296  Bit Score: 83.53  E-value: 1.33e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  47 SWSFWRAGIAEFIATFLFLYITVLTVMGVKRSPNmcaSVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARK 126
Cdd:PLN00184  50 SVPFLQKLIAEVLGTYFLVFTGCASVVVNMQNDN---VVTLPGIAIVWGLTIMVLIYSLGHISGAHINPAVTIAFASCGR 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 127 LSLTRALYYIVMQCLGAICGAGVVKGFQPKQYQALGGGANTVAHGYTKGSGLGAEIIGTFVLVYTVFSATDAKRNARdsH 206
Cdd:PLN00184 127 FPLKQVPAYVISQVIGSTLAAATLRLLFGLDHDVCSGKHDVFIGSSPVGSDLQAFVMEFIVTFYLMFIISGVATDNR--A 204

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 207 VPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNkdhSWDDHWVFWVGPFIGAALAA-LYHVV 275
Cdd:PLN00184 205 IGELAGLAIGSTVLLNVLIAAPVSSASMNPGRSLGPAMVYG---CYKGIWIYIVAPTLGAIAGAwVYNTV 271
PLN00182 PLN00182
putative aquaporin NIP4; Provisional
 55-266 2.47e-17

putative aquaporin NIP4; Provisional


Pssm-ID: 165748  Cd Length: 283  Bit Score: 79.95  E-value: 2.47e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  55 IAEFIATflflYITVLTVMGVKRSPNM-CASVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRAL 133
Cdd:PLN00182  46 IAEMIGT----YFIIFSGCGVVVVNVLyGGTITFPGICVTWGLIVMVMIYSTGHISGAHFNPAVTVTFAIFRRFPWYQVP 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 134 YYIVMQCLGAICGAGVVKGFQPKQYQALGGganTVAHGyTKGSGLGAEIIGTFVLVYTVFSATDAKRNARDshvpiLAPL 213
Cdd:PLN00182 122 LYIGAQLTGSLLASLTLRLMFNVTPEAFFG---TTPTD-SSGQALVAEIIISFLLMFVISGVATDSRAVGE-----LAGI 192

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 145332915 214 PIGFAVFLVHLATIPITGTGINPARSLGAAIIYnkdHSWDDHWVFWVGPFIGA 266
Cdd:PLN00182 193 AVGMTIILNVFVAGPISGASMNPARSLGPAIVM---GRYKGIWVYIVGPFVGI 242
PLN00026 PLN00026
aquaporin NIP; Provisional
 56-278 1.77e-15

aquaporin NIP; Provisional


Pssm-ID: 177663 [Multi-domain]  Cd Length: 298  Bit Score: 74.90  E-value: 1.77e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915  56 AEFIATFLFLYITVLTVMGVKRSPNmcaSVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRALYY 135
Cdd:PLN00026  76 AEFVGTFILIFAATAGPIVNQKYDG---AETLIGNAACAGLAVMIVILSTGHISGAHLNPSLTIAFAALRHFPWKHVPAY 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145332915 136 IVMQCLGAICGAGVVKG-FQPkqyqALGGGANTVAHGYtkGSGLGAEIIGTFVLVYTVFS-ATDAKRnardshVPILAPL 213
Cdd:PLN00026 153 IAAQVSASICASFALKGvFHP----FMSGGVTVPSVST--GQAFALEFIITFNLLFVVTAvATDTRA------VGELAGI 220

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 145332915 214 PIGFAVFLVHLATIPITGTGINPARSLGAAIIYNkdhSWDDHWVFWVGPFIGA-ALAALYHVVVIR 278
Cdd:PLN00026 221 AVGATVMLNILVAGPSTGGSMNPVRTLGPAVAAG---NYRAIWIYLVAPTLGAlAGAGTYTAVKLR 283
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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