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Conserved domains on  [gi|145333021|ref|NP_001078376|]
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OSBP(oxysterol binding protein)-related protein 2B [Arabidopsis thaliana]

Protein Classification

OSBP family protein( domain architecture ID 10472238)

OSBP (oxysterol-binding protein) family protein similar to oxysterol-binding protein that is a lipid transfer protein

Gene Ontology:  GO:0008289|GO:0008142|GO:0016020
SCOP:  4000415
TCDB:  2.D.1

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Oxysterol_BP pfam01237
Oxysterol-binding protein;
1-343 2.99e-169

Oxysterol-binding protein;


:

Pssm-ID: 460126  Cd Length: 366  Bit Score: 476.27  E-value: 2.99e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021    1 MIKDNVGKDLTRVCLPVYFNEPISSLQKCFEDLEYSYLLDQAYEygkSGKSLLRALNVAAFAVSGYASTEGRHCKPFNPL 80
Cdd:pfam01237   5 ILKKNIGKDLSKITMPVFFNEPLSLLQRLAEDLEYSELLDKAAE---EDDPLERMLYVAAFAVSGYSSTRRRVKKPFNPL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021   81 LGETYEADFPEKGIRFFSEKVSHHPTVIACHCEGKGWKFWGDTNLRSKFWGRSIQLEPVGILTLEF-DDGEIFQWSKVTT 159
Cdd:pfam01237  82 LGETFELVRPDKGFRFIAEQVSHHPPISAFHAESKGWTFWGEIAPKSKFWGKSLEVNPEGTVHLTLkKTGEHYTWTKPTT 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021  160 TIYNILLGKLYCDHHGIMKIRGNR-QYSCMLKFKEQSIL-DRNPHQVNGFVEDVTGKKAATVFGKWNDSLYYVAGDGINK 237
Cdd:pfam01237 162 YVHNIIFGKLWVEHYGEMTITNHTtGYKAVLEFKPKGYFsSGRSNEVTGKVYDKNGKVLYTLSGKWNESLYIKDVSTGKK 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021  238 A------------SASLLWKATKAPPNvtRYNFTSFAMTLNELIPGLE-LPPTDSRLRPDQRHLENGEYEKANEEKQRLE 304
Cdd:pfam01237 242 SseddsveeqpdgESRLLWKAGPLPNA--YYGFTSFAVTLNELTDELGkLPPTDSRLRPDQRALENGDIDEAEEEKLRLE 319
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 145333021  305 RRQRMSRQIQESG---WRPRWFE-----PQGESESYKYTGGYWEARD 343
Cdd:pfam01237 320 EKQRARRKEREEKgeeWKPRWFKkvkddPVTGEEYWKYKGGYWERRE 366
 
Name Accession Description Interval E-value
Oxysterol_BP pfam01237
Oxysterol-binding protein;
1-343 2.99e-169

Oxysterol-binding protein;


Pssm-ID: 460126  Cd Length: 366  Bit Score: 476.27  E-value: 2.99e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021    1 MIKDNVGKDLTRVCLPVYFNEPISSLQKCFEDLEYSYLLDQAYEygkSGKSLLRALNVAAFAVSGYASTEGRHCKPFNPL 80
Cdd:pfam01237   5 ILKKNIGKDLSKITMPVFFNEPLSLLQRLAEDLEYSELLDKAAE---EDDPLERMLYVAAFAVSGYSSTRRRVKKPFNPL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021   81 LGETYEADFPEKGIRFFSEKVSHHPTVIACHCEGKGWKFWGDTNLRSKFWGRSIQLEPVGILTLEF-DDGEIFQWSKVTT 159
Cdd:pfam01237  82 LGETFELVRPDKGFRFIAEQVSHHPPISAFHAESKGWTFWGEIAPKSKFWGKSLEVNPEGTVHLTLkKTGEHYTWTKPTT 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021  160 TIYNILLGKLYCDHHGIMKIRGNR-QYSCMLKFKEQSIL-DRNPHQVNGFVEDVTGKKAATVFGKWNDSLYYVAGDGINK 237
Cdd:pfam01237 162 YVHNIIFGKLWVEHYGEMTITNHTtGYKAVLEFKPKGYFsSGRSNEVTGKVYDKNGKVLYTLSGKWNESLYIKDVSTGKK 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021  238 A------------SASLLWKATKAPPNvtRYNFTSFAMTLNELIPGLE-LPPTDSRLRPDQRHLENGEYEKANEEKQRLE 304
Cdd:pfam01237 242 SseddsveeqpdgESRLLWKAGPLPNA--YYGFTSFAVTLNELTDELGkLPPTDSRLRPDQRALENGDIDEAEEEKLRLE 319
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 145333021  305 RRQRMSRQIQESG---WRPRWFE-----PQGESESYKYTGGYWEARD 343
Cdd:pfam01237 320 EKQRARRKEREEKgeeWKPRWFKkvkddPVTGEEYWKYKGGYWERRE 366
 
Name Accession Description Interval E-value
Oxysterol_BP pfam01237
Oxysterol-binding protein;
1-343 2.99e-169

Oxysterol-binding protein;


Pssm-ID: 460126  Cd Length: 366  Bit Score: 476.27  E-value: 2.99e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021    1 MIKDNVGKDLTRVCLPVYFNEPISSLQKCFEDLEYSYLLDQAYEygkSGKSLLRALNVAAFAVSGYASTEGRHCKPFNPL 80
Cdd:pfam01237   5 ILKKNIGKDLSKITMPVFFNEPLSLLQRLAEDLEYSELLDKAAE---EDDPLERMLYVAAFAVSGYSSTRRRVKKPFNPL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021   81 LGETYEADFPEKGIRFFSEKVSHHPTVIACHCEGKGWKFWGDTNLRSKFWGRSIQLEPVGILTLEF-DDGEIFQWSKVTT 159
Cdd:pfam01237  82 LGETFELVRPDKGFRFIAEQVSHHPPISAFHAESKGWTFWGEIAPKSKFWGKSLEVNPEGTVHLTLkKTGEHYTWTKPTT 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021  160 TIYNILLGKLYCDHHGIMKIRGNR-QYSCMLKFKEQSIL-DRNPHQVNGFVEDVTGKKAATVFGKWNDSLYYVAGDGINK 237
Cdd:pfam01237 162 YVHNIIFGKLWVEHYGEMTITNHTtGYKAVLEFKPKGYFsSGRSNEVTGKVYDKNGKVLYTLSGKWNESLYIKDVSTGKK 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333021  238 A------------SASLLWKATKAPPNvtRYNFTSFAMTLNELIPGLE-LPPTDSRLRPDQRHLENGEYEKANEEKQRLE 304
Cdd:pfam01237 242 SseddsveeqpdgESRLLWKAGPLPNA--YYGFTSFAVTLNELTDELGkLPPTDSRLRPDQRALENGDIDEAEEEKLRLE 319
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 145333021  305 RRQRMSRQIQESG---WRPRWFE-----PQGESESYKYTGGYWEARD 343
Cdd:pfam01237 320 EKQRARRKEREEKgeeWKPRWFKkvkddPVTGEEYWKYKGGYWERRE 366
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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