|
Name |
Accession |
Description |
Interval |
E-value |
| pyru_phos_dikin |
TIGR01828 |
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called ... |
84-945 |
0e+00 |
|
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called pyruvate,orthophosphate dikinase. It is similar in sequence to other PEP-utilizing enzymes. [Energy metabolism, Other]
Pssm-ID: 273822 [Multi-domain] Cd Length: 856 Bit Score: 1528.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 84 KRVFTFGkgrsEGNKGMKSLLGGKGANLAEMASIGLSVPPGLTISTEACQQYQIAGKKLPEGLWEEILEGLSFIERDIGA 163
Cdd:TIGR01828 2 KRVYAFG----EGNASMKNLLGGKGANLAEMTKLGLPVPPGFTITTEACNEYYANGKQFPKGLQEEIKEALTLLEEKTGK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 164 SLADPSKPLLLSVRSGAAISMPGMMDTVLNLGLNDQVVVGLAAKSG-ERFAYDSFRRFLDMFGDVVMGIPHAKFEEKLER 242
Cdd:TIGR01828 78 KFGDTENPLLVSVRSGAAVSMPGMMDTILNLGLNDETVEGLAKLTGnARFAYDSYRRFIQMFGDVVLGIPHELFEQILEA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 243 MKERKGVKNDTDLSAADLKELVEQYKSVYLEAKGQEFPSDPKKQLELAIEAVFDSWDSPRANKYRSINQITGLKGTAVNI 322
Cdd:TIGR01828 158 MKEEKGVKLDTDLTADDLKELIEKYKAIYREATGKPFPQDPKEQLELAIKAVFDSWNNPRAIVYRRLNDIPEDWGTAVNI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 323 QCMVFGNMGDTSGTGVLFTRNPSTGEKKLYGEFLVNAQGEDVVAGIRTPEDLDTMKRFMPEAYAELVENCNILERHYKDM 402
Cdd:TIGR01828 238 QSMVFGNMGETSGTGVAFTRNPSTGEKGLFGEFLINAQGEDVVAGIRTPQPITAMEADMPDVYKELLDIAEKLEGHYRDM 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 403 MDIEFTVQEERLWMLQCRAGKRTGKGAVKIAVDMVGEGLVEKSSAIKMVEPQHLDQLLHPQFHDPsgYREKVVAKGLPAS 482
Cdd:TIGR01828 318 QDIEFTIERGKLYMLQTRNGKRTAKAAVRIAVDMVKEGLITEEEAIMRVEPKSLDQLLHPRFDPS--ALKTVLAKGLPAS 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 483 PGAAVGQVVFTAEEAEAWHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRVDEN 562
Cdd:TIGR01828 396 PGAATGKIVFSAEDAVELAEKGKKVILVREETSPEDIEGMHVAEGILTARGGMTSHAAVVARGMGKCCVSGCEELKINEE 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 563 HKVLLIGDLTINEGEWISMNGSTGEVILGKQALAPPALSPDLETFMSWADAIRRLKVMANADTPEDAIAARKNGAQGIGL 642
Cdd:TIGR01828 476 AKTFTIGGRVFHEGDIISIDGSTGEIYLGEIPLIEPSVSGDFETIMDWADKIRKLKVRANADTPEDALTARKFGAEGIGL 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 643 CRTEHMFFGADRIKAVRKMIMAVTTEQRKASLDILLPYQRSDFEGIFRAMDGLPVTIRLLDPPLHEFLPegDLDNIVHEL 722
Cdd:TIGR01828 556 CRTEHMFFGAERIPAVRKMILADSEEERQKALNKLLPFQKEDFKGLFKAMEGLPVTIRLLDPPLHEFLP--HTEELQKEL 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 723 AEETGVKEDEVLSRIEKLSEVNPMLGFRGCRLGISYPELTEMQARAIFEAAASMQDQGVTVIPEIMVPLVGTPQELGHQV 802
Cdd:TIGR01828 634 AEDMGLTLAEILKRVEELHEVNPMLGHRGCRLGITYPEIYEMQVRAIMEAAVEVKKEGIDVHPEIMIPLVGEKNELKILK 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 803 DVIRKVAKKVFAEKGHTVSYKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRDDVGKFLPIYLAKGILQHD 882
Cdd:TIGR01828 714 DVLEEVAAEVFKEYGVTVPYEIGTMIEIPRAALTADKIAEEADFFSFGTNDLTQMTFGFSRDDAGKFLPKYLEKGILEKD 793
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 145333150 883 PFEVLDQQGVGQLIKMATEKGRAARPSLKVGICGEHGGDPSSVGFFAEAGLDYVSCSPFRVPI 945
Cdd:TIGR01828 794 PFESLDQTGVGQLMRMAVEKGRQTRPNLKVGICGEHGGDPSSIEFCHKIGLNYVSCSPYRVPI 856
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
101-626 |
1.49e-163 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 489.64 E-value: 1.49e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 101 KSLLGGKGANLAEMASIGLSVPPGLTISTEACQQYQIAGKKLPEGLWEEILEGLSFIERDIGASLADPSKPLLLSVRSGA 180
Cdd:PRK05878 20 RELLGGKGHGIDMMRRLGLPVPPAFCITTEVCVRYLADPGSTIDAIWDDVLDRMRWLEAETGRTFGRGPRPLLVSVRSGA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 181 AISMPGMMDTVLNLGLNDQVVVGLAAKSG-ERFAYDSFRRFLDMFGDVVMgiphakfeeklermkerkgvkndtdlsaad 259
Cdd:PRK05878 100 AQSMPGMMDTILNLGINDAVEQALAAEGGdPDFAADTRRRFTEMYRRIVG------------------------------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 260 lkelveqyksvyleaKGQEFPSDPKKQLELAIEAVFDSWDSPRANKYRSINQITGLKGTAVNIQCMVFGNMGDTSGTGVL 339
Cdd:PRK05878 150 ---------------SGSPPPDDPYEQLRAAIEAVFASWNSPRAVAYRRHHGLDDDGGTAVVVQAMVFGNLDANSGTGVL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 340 FTRNPSTGEKKLYGEFLVNAQGEDVVAGIRTPEDLDTMKRFMPEAYAELVENCNILERHYKDMMDIEFTVQEERLWMLQC 419
Cdd:PRK05878 215 FSRNPITGANEPFGEWLPGGQGEDVVSGLVDVAPITALRDEQPAVYDELMAAARTLERLGRDVQDIEFTVESGKLWLLQT 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 420 RAGKRTGKGAVKIAVDMVGEGLVEKSSAIKMVEPQHLDQLLHPQFHDPSGYREKVVAKGLPASPGAAVGQVVFTAEEAEA 499
Cdd:PRK05878 295 RSAKRSAQAAVRLALQLHDEGLIDDAEALRRVTPTHVETLLRPSLQPEARLAAPLLAKGLPACPGVVSGTAYTDVDEALD 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 500 WHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEirvdenhkvlliGDLTINEGEWI 579
Cdd:PRK05878 375 AADRGEPVILVRDHTRPDDVHGMLAAQGIVTEVGGATSHAAVVSRELGRVAVVGCGA------------GVAAALAGKEI 442
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 145333150 580 SMNGSTGEVILGKQALAPPALS--PDLETFMSWADAIRRLKVMANADTP 626
Cdd:PRK05878 443 TVDGYEGEVRQGVLALSAWSESdtPELRELADIAQRISPLRAHASGDYP 491
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
83-588 |
8.69e-143 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 433.10 E-value: 8.69e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 83 QKRVFTFgkgrSEGNKGMKSLLGGKGANLAEMASIGLSVPPGLTISTEACQQY--------------------------- 135
Cdd:COG0574 2 TKYVYWF----AEGGADDVDLVGGKGANLGEMTRLGLPVPPGFTITTEAYRRFleengleeeirelladldvddvdalae 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 136 -------QIAGKKLPEGLWEEILEGLSFIERDIGASLadpskplLLSVRSGAA------ISMPGMMDTVLNLglndqvvv 202
Cdd:COG0574 78 asaeireLILEAPLPEELEEEILAAYAKLEEKFGEDL-------LVAVRSSATaedlpdASFAGQMDTVLNV-------- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 203 glaakSGErfaydsfrrfldmfgdvvmgiphakfeeklermkerkgvkndtdlsaadlkelveqyksvyleakgqefpsd 282
Cdd:COG0574 143 -----NGN------------------------------------------------------------------------ 145
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 283 pkKQLELAIEAVFDSWDSPRANKYRSINQITGLK-GTAVNIQCMVFGNMgdtSGTGVLFTRNPSTGEKK-LYGEFLvNAQ 360
Cdd:COG0574 146 --EQLLEAIKAVFASLFTDRAIAYRRHNGIDHDDvGTAVNVQAMVFGNM---SASGVMFTRDPSTGEKDvVYIEAL-NGL 219
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 361 GEDVVAGIRTPEDLDTMKRFM----------------------------------PEAYAELVENCNILERHYKDMMDIE 406
Cdd:COG0574 220 GEDVVAGIVTPDPYYVDKPTIlertlgskaikmvydggtvevpvppeernrpsltDEEYLELARIALRLEKHYGDPQDIE 299
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 407 FTVQEERLWMLQCRAgkrtgkgavkIAVdMvgEGLVEKSsAIKMVEPQHLDQLLHPQFHDPSGYREKVVAKGLPASPGAA 486
Cdd:COG0574 300 WAIDDGKLYILQTRP----------ITV-L--EGLITKE-ALLRVDPAQLDQLLHPRFDPKAKEEGEVLAKGLPASPGAA 365
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 487 VGQVVFTAEEAEaWHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRVdenhkvl 566
Cdd:COG0574 366 SGKVVFIADEAE-LARFQEGVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATR------- 437
|
570 580
....*....|....*....|..
gi 145333150 567 ligdlTINEGEWISMNGSTGEV 588
Cdd:COG0574 438 -----VLKDGDEITVDGTTGEV 454
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
598-953 |
7.79e-117 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 359.31 E-value: 7.79e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 598 PALSPDLETFMSWADAIRRLKVMANADTPEDAIAARKNGAQGIGLCRTEHMFFGADRIKAVRKmimavtteqrkasldil 677
Cdd:pfam02896 1 KAELGKLKDLPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDE----------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 678 lpyQRSDFEGIFRAMDGLPVTIRLLDPPLHEFLPEGDLdnivhelaeetgvkedevlsriekLSEVNPMLGFRGCRLGIS 757
Cdd:pfam02896 64 ---QFEAYKGVLEAMNGRPVTVRTLDIGGDKELPYLEE------------------------PEEMNPFLGWRGIRIGLD 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 758 YPELTEMQARAIFEAAASMQdqgvtviPEIMVPLVGTPQELGHQVDVIRKVAKKVFAEKGHTVSYKVGTMIEIPRAALIA 837
Cdd:pfam02896 117 RPELFRTQLRAILRASAFGN-------LRIMFPMVASVEELREAKAIIEEVKEELDAEVGFDKDIKVGIMIEVPSAALLA 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 838 DEIAKEAEFFSFGTNDLTQMTFGYSRDDVGkflPIYLakgilqHDPFEVLDQQGVGQLIKMATEKGraarpsLKVGICGE 917
Cdd:pfam02896 190 DQLAKEVDFFSIGTNDLTQYTLAVDRDNER---VAYL------YDPLHPAVLRLIKEVIRAAHRHG------KWVGICGE 254
|
330 340 350
....*....|....*....|....*....|....*.
gi 145333150 918 HGGDPSSVGFFAEAGLDYVSCSPFRVPIARLAAAQV 953
Cdd:pfam02896 255 MAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLAQI 290
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pyru_phos_dikin |
TIGR01828 |
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called ... |
84-945 |
0e+00 |
|
pyruvate, phosphate dikinase; This model represents pyruvate,phosphate dikinase, also called pyruvate,orthophosphate dikinase. It is similar in sequence to other PEP-utilizing enzymes. [Energy metabolism, Other]
Pssm-ID: 273822 [Multi-domain] Cd Length: 856 Bit Score: 1528.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 84 KRVFTFGkgrsEGNKGMKSLLGGKGANLAEMASIGLSVPPGLTISTEACQQYQIAGKKLPEGLWEEILEGLSFIERDIGA 163
Cdd:TIGR01828 2 KRVYAFG----EGNASMKNLLGGKGANLAEMTKLGLPVPPGFTITTEACNEYYANGKQFPKGLQEEIKEALTLLEEKTGK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 164 SLADPSKPLLLSVRSGAAISMPGMMDTVLNLGLNDQVVVGLAAKSG-ERFAYDSFRRFLDMFGDVVMGIPHAKFEEKLER 242
Cdd:TIGR01828 78 KFGDTENPLLVSVRSGAAVSMPGMMDTILNLGLNDETVEGLAKLTGnARFAYDSYRRFIQMFGDVVLGIPHELFEQILEA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 243 MKERKGVKNDTDLSAADLKELVEQYKSVYLEAKGQEFPSDPKKQLELAIEAVFDSWDSPRANKYRSINQITGLKGTAVNI 322
Cdd:TIGR01828 158 MKEEKGVKLDTDLTADDLKELIEKYKAIYREATGKPFPQDPKEQLELAIKAVFDSWNNPRAIVYRRLNDIPEDWGTAVNI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 323 QCMVFGNMGDTSGTGVLFTRNPSTGEKKLYGEFLVNAQGEDVVAGIRTPEDLDTMKRFMPEAYAELVENCNILERHYKDM 402
Cdd:TIGR01828 238 QSMVFGNMGETSGTGVAFTRNPSTGEKGLFGEFLINAQGEDVVAGIRTPQPITAMEADMPDVYKELLDIAEKLEGHYRDM 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 403 MDIEFTVQEERLWMLQCRAGKRTGKGAVKIAVDMVGEGLVEKSSAIKMVEPQHLDQLLHPQFHDPsgYREKVVAKGLPAS 482
Cdd:TIGR01828 318 QDIEFTIERGKLYMLQTRNGKRTAKAAVRIAVDMVKEGLITEEEAIMRVEPKSLDQLLHPRFDPS--ALKTVLAKGLPAS 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 483 PGAAVGQVVFTAEEAEAWHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRVDEN 562
Cdd:TIGR01828 396 PGAATGKIVFSAEDAVELAEKGKKVILVREETSPEDIEGMHVAEGILTARGGMTSHAAVVARGMGKCCVSGCEELKINEE 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 563 HKVLLIGDLTINEGEWISMNGSTGEVILGKQALAPPALSPDLETFMSWADAIRRLKVMANADTPEDAIAARKNGAQGIGL 642
Cdd:TIGR01828 476 AKTFTIGGRVFHEGDIISIDGSTGEIYLGEIPLIEPSVSGDFETIMDWADKIRKLKVRANADTPEDALTARKFGAEGIGL 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 643 CRTEHMFFGADRIKAVRKMIMAVTTEQRKASLDILLPYQRSDFEGIFRAMDGLPVTIRLLDPPLHEFLPegDLDNIVHEL 722
Cdd:TIGR01828 556 CRTEHMFFGAERIPAVRKMILADSEEERQKALNKLLPFQKEDFKGLFKAMEGLPVTIRLLDPPLHEFLP--HTEELQKEL 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 723 AEETGVKEDEVLSRIEKLSEVNPMLGFRGCRLGISYPELTEMQARAIFEAAASMQDQGVTVIPEIMVPLVGTPQELGHQV 802
Cdd:TIGR01828 634 AEDMGLTLAEILKRVEELHEVNPMLGHRGCRLGITYPEIYEMQVRAIMEAAVEVKKEGIDVHPEIMIPLVGEKNELKILK 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 803 DVIRKVAKKVFAEKGHTVSYKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRDDVGKFLPIYLAKGILQHD 882
Cdd:TIGR01828 714 DVLEEVAAEVFKEYGVTVPYEIGTMIEIPRAALTADKIAEEADFFSFGTNDLTQMTFGFSRDDAGKFLPKYLEKGILEKD 793
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 145333150 883 PFEVLDQQGVGQLIKMATEKGRAARPSLKVGICGEHGGDPSSVGFFAEAGLDYVSCSPFRVPI 945
Cdd:TIGR01828 794 PFESLDQTGVGQLMRMAVEKGRQTRPNLKVGICGEHGGDPSSIEFCHKIGLNYVSCSPYRVPI 856
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
101-626 |
1.49e-163 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 489.64 E-value: 1.49e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 101 KSLLGGKGANLAEMASIGLSVPPGLTISTEACQQYQIAGKKLPEGLWEEILEGLSFIERDIGASLADPSKPLLLSVRSGA 180
Cdd:PRK05878 20 RELLGGKGHGIDMMRRLGLPVPPAFCITTEVCVRYLADPGSTIDAIWDDVLDRMRWLEAETGRTFGRGPRPLLVSVRSGA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 181 AISMPGMMDTVLNLGLNDQVVVGLAAKSG-ERFAYDSFRRFLDMFGDVVMgiphakfeeklermkerkgvkndtdlsaad 259
Cdd:PRK05878 100 AQSMPGMMDTILNLGINDAVEQALAAEGGdPDFAADTRRRFTEMYRRIVG------------------------------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 260 lkelveqyksvyleaKGQEFPSDPKKQLELAIEAVFDSWDSPRANKYRSINQITGLKGTAVNIQCMVFGNMGDTSGTGVL 339
Cdd:PRK05878 150 ---------------SGSPPPDDPYEQLRAAIEAVFASWNSPRAVAYRRHHGLDDDGGTAVVVQAMVFGNLDANSGTGVL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 340 FTRNPSTGEKKLYGEFLVNAQGEDVVAGIRTPEDLDTMKRFMPEAYAELVENCNILERHYKDMMDIEFTVQEERLWMLQC 419
Cdd:PRK05878 215 FSRNPITGANEPFGEWLPGGQGEDVVSGLVDVAPITALRDEQPAVYDELMAAARTLERLGRDVQDIEFTVESGKLWLLQT 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 420 RAGKRTGKGAVKIAVDMVGEGLVEKSSAIKMVEPQHLDQLLHPQFHDPSGYREKVVAKGLPASPGAAVGQVVFTAEEAEA 499
Cdd:PRK05878 295 RSAKRSAQAAVRLALQLHDEGLIDDAEALRRVTPTHVETLLRPSLQPEARLAAPLLAKGLPACPGVVSGTAYTDVDEALD 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 500 WHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEirvdenhkvlliGDLTINEGEWI 579
Cdd:PRK05878 375 AADRGEPVILVRDHTRPDDVHGMLAAQGIVTEVGGATSHAAVVSRELGRVAVVGCGA------------GVAAALAGKEI 442
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 145333150 580 SMNGSTGEVILGKQALAPPALS--PDLETFMSWADAIRRLKVMANADTP 626
Cdd:PRK05878 443 TVDGYEGEVRQGVLALSAWSESdtPELRELADIAQRISPLRAHASGDYP 491
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
83-588 |
8.69e-143 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 433.10 E-value: 8.69e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 83 QKRVFTFgkgrSEGNKGMKSLLGGKGANLAEMASIGLSVPPGLTISTEACQQY--------------------------- 135
Cdd:COG0574 2 TKYVYWF----AEGGADDVDLVGGKGANLGEMTRLGLPVPPGFTITTEAYRRFleengleeeirelladldvddvdalae 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 136 -------QIAGKKLPEGLWEEILEGLSFIERDIGASLadpskplLLSVRSGAA------ISMPGMMDTVLNLglndqvvv 202
Cdd:COG0574 78 asaeireLILEAPLPEELEEEILAAYAKLEEKFGEDL-------LVAVRSSATaedlpdASFAGQMDTVLNV-------- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 203 glaakSGErfaydsfrrfldmfgdvvmgiphakfeeklermkerkgvkndtdlsaadlkelveqyksvyleakgqefpsd 282
Cdd:COG0574 143 -----NGN------------------------------------------------------------------------ 145
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 283 pkKQLELAIEAVFDSWDSPRANKYRSINQITGLK-GTAVNIQCMVFGNMgdtSGTGVLFTRNPSTGEKK-LYGEFLvNAQ 360
Cdd:COG0574 146 --EQLLEAIKAVFASLFTDRAIAYRRHNGIDHDDvGTAVNVQAMVFGNM---SASGVMFTRDPSTGEKDvVYIEAL-NGL 219
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 361 GEDVVAGIRTPEDLDTMKRFM----------------------------------PEAYAELVENCNILERHYKDMMDIE 406
Cdd:COG0574 220 GEDVVAGIVTPDPYYVDKPTIlertlgskaikmvydggtvevpvppeernrpsltDEEYLELARIALRLEKHYGDPQDIE 299
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 407 FTVQEERLWMLQCRAgkrtgkgavkIAVdMvgEGLVEKSsAIKMVEPQHLDQLLHPQFHDPSGYREKVVAKGLPASPGAA 486
Cdd:COG0574 300 WAIDDGKLYILQTRP----------ITV-L--EGLITKE-ALLRVDPAQLDQLLHPRFDPKAKEEGEVLAKGLPASPGAA 365
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 487 VGQVVFTAEEAEaWHSQGKTVILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRVdenhkvl 566
Cdd:COG0574 366 SGKVVFIADEAE-LARFQEGVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATR------- 437
|
570 580
....*....|....*....|..
gi 145333150 567 ligdlTINEGEWISMNGSTGEV 588
Cdd:COG0574 438 -----VLKDGDEITVDGTTGEV 454
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
598-953 |
7.79e-117 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 359.31 E-value: 7.79e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 598 PALSPDLETFMSWADAIRRLKVMANADTPEDAIAARKNGAQGIGLCRTEHMFFGADRIKAVRKmimavtteqrkasldil 677
Cdd:pfam02896 1 KAELGKLKDLPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDE----------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 678 lpyQRSDFEGIFRAMDGLPVTIRLLDPPLHEFLPEGDLdnivhelaeetgvkedevlsriekLSEVNPMLGFRGCRLGIS 757
Cdd:pfam02896 64 ---QFEAYKGVLEAMNGRPVTVRTLDIGGDKELPYLEE------------------------PEEMNPFLGWRGIRIGLD 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 758 YPELTEMQARAIFEAAASMQdqgvtviPEIMVPLVGTPQELGHQVDVIRKVAKKVFAEKGHTVSYKVGTMIEIPRAALIA 837
Cdd:pfam02896 117 RPELFRTQLRAILRASAFGN-------LRIMFPMVASVEELREAKAIIEEVKEELDAEVGFDKDIKVGIMIEVPSAALLA 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 838 DEIAKEAEFFSFGTNDLTQMTFGYSRDDVGkflPIYLakgilqHDPFEVLDQQGVGQLIKMATEKGraarpsLKVGICGE 917
Cdd:pfam02896 190 DQLAKEVDFFSIGTNDLTQYTLAVDRDNER---VAYL------YDPLHPAVLRLIKEVIRAAHRHG------KWVGICGE 254
|
330 340 350
....*....|....*....|....*....|....*.
gi 145333150 918 HGGDPSSVGFFAEAGLDYVSCSPFRVPIARLAAAQV 953
Cdd:pfam02896 255 MAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLAQI 290
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
94-953 |
2.64e-66 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 238.10 E-value: 2.64e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 94 SEGNKGMKSLLGGKGANLAEM----ASIGLSVPPGLTISTEACQQYqiagkkLPE-GLWEEILEGLSFIERDIGASLADP 168
Cdd:TIGR01418 6 EEVRKDDVPLVGGKNASLGEMiqnlSPAGVPVPPGFVVTAEAYRYF------LEEnGIAQKIRDLLEELDVEDVDALAAA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 169 SKplllSVRSGaaismpgMMDTVLNLGLNDQVvvglaaksgeRFAYDsfrrfldmfgdvvmgiphaKFEEKLERMKERKG 248
Cdd:TIGR01418 80 SA----EIREL-------ILNTPFPPDLEEAI----------REAYD-------------------KLSEDYGKEEADVA 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 249 VKNDTdlSAADLKE--LVEQyKSVYLEAKGQEfpsdpkkQLELAIEAVFDSWDSPRANKYRSINQITGLK-GTAVNIQCM 325
Cdd:TIGR01418 120 VRSSA--TAEDLPDasFAGQ-QETYLNVTGEE-------EVLEHVKKCWASLFTDRAISYRVSQGFDHEKvAIAVGVQKM 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 326 VFGNMGDTsgtGVLFTRNPSTGEKKlygEFLVNAQ---GEDVVAGIRTPE-------DLDTMKRFMPEA----------Y 385
Cdd:TIGR01418 190 VRSDLGSS---GVMFTIDTETGFKD---AVFIESAwglGEAVVGGAVTPDeyvvfkpTLEQGKKAILERtlgskkikmvY 263
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 386 A-----------------------------ELVENCNILERHYKDMMDIEFTV--QEERLWMLQCRAGKRTGKGavkiav 434
Cdd:TIGR01418 264 DpdgggvetkivevpeeerdafslsdeeilELAKLAVLIEKHYGRPMDIEWAKdgFDGEIFIVQARPETVQSRK------ 337
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 435 dmvGEGLVEKSSAIKMvepqhldqllhpqfhdpsgyREKVVAKGLPASPGAAVG--QVVFTAEEAeawHSQGKTVILVRT 512
Cdd:TIGR01418 338 ---KKENVEERYELKG--------------------KGKVLVTGRAAGPGIASGkvKVIFDLKEM---DKFEEGDILVTD 391
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 513 ETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCseirvdenhkvlliGDLT--INEGEWISMNGS---TGE 587
Cdd:TIGR01418 392 MTDPDWEPAMKRASAIVTNEGGMTCHAAIVARELGIPAVVGT--------------GDATktLKDGMEVTVDCAegdTGY 457
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 588 VILGKqaLAPPALSPDLETFmswadAIRRLKVMANADTPEDAIAARKNGAQGIGLCRTEHMFFGADRIKAVRKMIMAVTT 667
Cdd:TIGR01418 458 VYAGK--LEHEVKEVELSNM-----PVTATKIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLE 530
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 668 EQRKASLDILLPYQRSDF------EGIFR---AMDGLPVTIRLLDPPLHEFlpegdldnivhelAEETGVKEDEvlsrie 738
Cdd:TIGR01418 531 SVEKNEIEELMAGNPRDFfvdklaEGIAKvaaAFYPKPVIVRTSDFKSNEY-------------RNLIGGEEYE------ 591
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 739 kLSEVNPMLGFRGCRLGIS--YPELTEMQARAIFEAAASMqdqGVTVIpEIMVPLVGTPQELghqvdvirKVAKKVFAEK 816
Cdd:TIGR01418 592 -PDEENPMLGWRGASRYYSesYEEAFRLECRAIKRVREEM---GLTNV-EVMIPFVRTPEEG--------KRALEIMAEE 658
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 817 GHTV---SYKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRDDvgkflpiylakGILQHdpfeVLDQQ--G 891
Cdd:TIGR01418 659 GLRRgknGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDS-----------GLVAH----LFDERnpA 723
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 145333150 892 VGQLIKMATEKgrAARPSLKVGICGEHGGD-PSSVGFFAEAGLDYVSCSPFRVPIARLAAAQV 953
Cdd:TIGR01418 724 VLRLIEMAIKA--AKEHGKKVGICGQAPSDyPEVVEFLVEEGIDSISLNPDAVLRTRLQVAEV 784
|
|
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
103-953 |
2.69e-58 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 215.00 E-value: 2.69e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 103 LLGGKGANLAEM----ASIGLSVPPGLTISTEA-------------------------CQQYQIAGKK---------LPE 144
Cdd:PRK06464 20 LVGGKNASLGEMisnlSGAGVPVPPGFATTAEAyryfleqtglnekiyelldgldvddVDALAKAGAQirqliidtpFPP 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 145 GLWEEILEG---LSfiERDIGASLAdpskplllsVRSGA-AISMP-----GMMDTVLNlglndqvVVGLaaksgerfayd 215
Cdd:PRK06464 100 DLEQEIREAyakLS--AGYGEASVA---------VRSSAtAEDLPdasfaGQQETFLN-------VRGI----------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 216 sfrrfldmfgdvvmgiphakfEEKLERMKErkgvkndtdlsaadlkelveqyksvyleakgqefpsdpkkqlelaieaVF 295
Cdd:PRK06464 151 ---------------------DDVLEAVKE------------------------------------------------CF 161
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 296 DSWDSPRANKYRSINQITGLK-GTAVNIQCMVFGnmgDTSGTGVLFTRNPSTGEKKL------YGefLvnaqGEDVVAGI 368
Cdd:PRK06464 162 ASLFTDRAISYRVHQGFDHFKvALSAGVQKMVRS---DLAASGVMFTLDTESGFRDVvfitasWG--L----GEMVVQGA 232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 369 RTPE----DLDTM--------------KRFM----------------PEAYA-----------ELVENCNILERHYKDMM 403
Cdd:PRK06464 233 VNPDefyvHKPTLkagkpaivrrtlgsKKIKmvyddggehgvktvdvPEEERnrfsltdeevlELAKQAVIIEKHYGRPM 312
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 404 DIEFTV--QEERLWMLQCRAgkRTgkgavkiavdmvgeglVEKSSAIKMVEPQHLDQllhpqfhdpsgyREKVVAKGLPA 481
Cdd:PRK06464 313 DIEWAKdgDDGKLYIVQARP--ET----------------VKSRKEANVLERYKLKG------------QGKVLVEGRAI 362
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 482 SPGAAVG--QVVFTAEEAEAWhSQGKtvILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRv 559
Cdd:PRK06464 363 GPGIGSGkvRVILDISEMDKV-QPGD--VLVTDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNAT- 438
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 560 denhKVLLIGDL-TINEGEwismnGSTGEVILGKqaLAPPALSPDLETFmswadAIRRLKVMANADTPEDAIAARKNGAQ 638
Cdd:PRK06464 439 ----EVLKDGQEvTVSCAE-----GDTGYVYEGL--LEFEVEEVSLEEM-----PETPTKIMMNVGNPERAFDFAALPND 502
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 639 GIGLCRTEHMFfgADRIKAVRKMIM---AVTTEQRKASLDILLPYQ-RSDF------EGI---FRAMDGLPVTIRLLDPP 705
Cdd:PRK06464 503 GVGLARLEFII--NNMIGVHPLALLefdQQDADLKAEIEELTAGYAsPEEFyvdklaEGIatvAAAFYPKPVIVRLSDFK 580
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 706 LHEF--LPEGDLdnivHELAEEtgvkedevlsrieklsevNPMLGFRGCRLGIS--YPELTEMQARAIFEAAASMqdqGV 781
Cdd:PRK06464 581 SNEYanLIGGER----YEPEEE------------------NPMLGFRGASRYLSesFREAFALECEAIKRVREEM---GL 635
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 782 TVIpEIMVPLVGTPQElghqvdvIRKVaKKVFAEKG---HTVSYKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMT 858
Cdd:PRK06464 636 TNV-EVMIPFVRTVEE-------AEKV-IELLAENGlkrGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLT 706
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 859 FGYSRDDvgkflpiylakGILQHDpFEVLDqQGVGQLIKMATEKGRAARpsLKVGICGEHGGD-PSSVGFFAEAGLDYVS 937
Cdd:PRK06464 707 LGLDRDS-----------GLVAHL-FDERN-PAVKKLISMAIKAAKKAG--KYVGICGQAPSDhPDFAEWLVEEGIDSIS 771
|
970
....*....|....*.
gi 145333150 938 CSPFRVPIARLAAAQV 953
Cdd:PRK06464 772 LNPDAVVDTWLAVAEV 787
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
507-947 |
4.52e-58 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 209.93 E-value: 4.52e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 507 VILVRTETSPDDVGGMHAAE--GILTARGGMTSHAAVVARGWGKCCIAGCSEIRvdenhkvlligdLTINEGEWISMNGS 584
Cdd:COG1080 155 VILVAHDLTPSDTAQLDPSRvaGFVTDLGGRTSHTAILARSLGIPAVVGLGDAL------------LLVKDGDLVIVDGD 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 585 TGEVILgkqalAPPAlsPDLETFMSWADAIRRLK--------------------VMANADTPEDAIAARKNGAQGIGLCR 644
Cdd:COG1080 223 AGVVIV-----NPDE--ETLAEYRERQAEYAAERaelarlrdlpavtldgvrveLAANIGLPEDAAAALENGAEGVGLFR 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 645 TEHMFFGADRikavrkmimAVT-TEQRKAsldillpYQRsdfegIFRAMDGLPVTIRLLD-------PPLHefLPEgdld 716
Cdd:COG1080 296 TEFLFMDRDD---------LPTeEEQFEA-------YRA-----VAEAMGGRPVTIRTLDiggdkplPYLP--LPK---- 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 717 nivhelaeetgvkedevlsrieklsEVNPMLGFRGCRLGISYPELTEMQARAIFEAAA--SMQdqgvtvipeIMVPLVGT 794
Cdd:COG1080 349 -------------------------EENPFLGLRAIRLCLDRPELFRTQLRAILRASAhgNLR---------IMFPMISS 394
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 795 PQELgHQV-DVIRKVAKKVfAEKGHTVS--YKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRDD--VGkf 869
Cdd:COG1080 395 VEEL-RQAkALLEEAKAEL-RAEGIPFDedIPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNekVA-- 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 870 lpiYLakgilqHDPFE--VLdqqgvgQLIKMATEKGRAA-RPslkVGICGEHGGDPSSVGFFAEAGLDYVSCSPFRVPIA 946
Cdd:COG1080 471 ---YL------YDPLHpaVL------RLIKMVIDAAHKAgKP---VGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAV 532
|
.
gi 145333150 947 R 947
Cdd:COG1080 533 K 533
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
102-441 |
9.93e-47 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 170.46 E-value: 9.93e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 102 SLLGGKGANLAEM-ASIGLSVPPGLTISTEACQQY-------------------------QIAGKK---------LPEGL 146
Cdd:pfam01326 2 NLVGGKGANLGEMlNDAGIPVPPGFAITADAYREFleenglrekidellkdldvddvdelREASKEirqlilsapLPEEL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 147 WEEILEglsfIERDIGASLADPskPLLLSVRSGAAI------SMPGMMDTVLNLGLNDQVVVglaaksgerfaydsfrrf 220
Cdd:pfam01326 82 EEAIRE----AYEELGKKFGDE--PLPVAVRSSATAedlpdaSFAGQQDTYLNVGGNDEVLE------------------ 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 221 ldmfgdvvmgiphakfeeklermkerkgvkndtdlsaadlkelveqyksvyleakgqefpsdpkkqlelAIEAVFDSWDS 300
Cdd:pfam01326 138 ---------------------------------------------------------------------AIKAVFASLFN 148
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 301 PRANKYRSINQITGLK-GTAVNIQCMVFGNmgdtsGTGVLFTRNPSTGEKklyGEFLVNA---QGEDVVAGIRTP----- 371
Cdd:pfam01326 149 DRAIAYRREKGIDHEDvALAVGVQRMVRSD-----ASGVMFSRDPETGFR---DEVLINAswgLGEAVVQGRVTPdefyv 220
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 372 -----------------------EDLDTMKRFMPEAYA-----------ELVENCNILERHYKDMMDIEFTVQ--EERLW 415
Cdd:pfam01326 221 fkptleilrrtigekeikmvydeGGEGTKEVEVPEEKRerfslsdeevlELARIAKKIEKHYGTPMDIEWAIDgrDGKLY 300
|
410 420
....*....|....*....|....*.
gi 145333150 416 MLQCRAGKRTGKGAVKIAVDMVGEGL 441
Cdd:pfam01326 301 ILQARPETVWSEAMEKIAAEILEEGL 326
|
|
| PTS_I_fam |
TIGR01417 |
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ... |
505-947 |
4.92e-39 |
|
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.
Pssm-ID: 273611 [Multi-domain] Cd Length: 565 Bit Score: 153.79 E-value: 4.92e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 505 KTVILVRTETSPDDVGGMHA--AEGILTARGGMTSHAAVVARGWGKCCIAGCSEIrvdenhkvlligDLTINEGEWISMN 582
Cdd:TIGR01417 153 DEVILVAEDLTPSETAQLNLkyVKGFLTDAGGKTSHTAIMARSLEIPAIVGTKSV------------TSQVKNGDTVIID 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 583 GSTGEVILgkqalappalSPDLETFMSWADAIRR-----------------------LKVMANADTPEDAIAARKNGAQG 639
Cdd:TIGR01417 221 GVKGIVIF----------NPSSETIDKYEAKQEAvssekaelaklkdkpaitldghqVELAANIGTVDDVEGAERNGGEG 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 640 IGLCRTEHMFFGADRikavrkmimavtteqrkasldilLPYQRSDFEG---IFRAMDGLPVTIRLLDpplheflpegdld 716
Cdd:TIGR01417 291 IGLFRTEFLYMSRDQ-----------------------LPTEEEQFAAyktVLEAMESDAVIVRTLD------------- 334
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 717 nivhelaeetgVKEDEVLSRIEKLSEVNPMLGFRGCRLGISYPELTEMQARAIFEAAasmqDQGVTvipEIMVPLVGTPQ 796
Cdd:TIGR01417 335 -----------IGGDKELPYLNFPKEENPFLGYRAIRLALEREEILRTQLRAILRAS----AYGKL---RIMFPMVATVE 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 797 ELgHQVDVIRKVAKKVFAEKGHTVS--YKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRddvGKFLPIYL 874
Cdd:TIGR01417 397 EI-RAVKQELEEEKQELNDEGKAFDenIEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDR---GNDLISNL 472
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 145333150 875 akgilqHDPFevldQQGVGQLIKMATEKGRAArpSLKVGICGEHGGDPSSVGFFAEAGLDYVSCSPFRVPIAR 947
Cdd:TIGR01417 473 ------YQPY----NPAVLRLIKLVIDAAKAE--GIWVGMCGEMAGDERAIPLLLGLGLRELSMSASSILRIK 533
|
|
| PRK11177 |
PRK11177 |
phosphoenolpyruvate-protein phosphotransferase PtsI; |
507-944 |
3.91e-26 |
|
phosphoenolpyruvate-protein phosphotransferase PtsI;
Pssm-ID: 183017 [Multi-domain] Cd Length: 575 Bit Score: 114.34 E-value: 3.91e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 507 VILVRTETSPDDVGGMHAAE--GILTARGGMTSHAAVVARGWGKCCIAGCSEIRVDENHKVLLIGDLTINEgewISMNGS 584
Cdd:PRK11177 156 VILVAADLTPSETAQLNLKKvlGFITDIGGRTSHTSIMARSLELPAIVGTGNITKQVKNGDYLILDAVNNQ---IYVNPT 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 585 TGEV----------ILGKQALAP----PALSPDLetfmswadaiRRLKVMANADTPEDAIAARKNGAQGIGLCRTEHMFF 650
Cdd:PRK11177 233 NEVIeelkavqeqyASEKAELAKlkdlPAITLDG----------HQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFM 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 651 GADrikavrkmimAVTTEQRkasldillpyQRSDFEGIFRAMDGLPVTIRLLDpplheflpegdldnivhelaeetgVKE 730
Cdd:PRK11177 303 DRD----------ALPTEEE----------QFQAYKAVAEAMGSQAVIVRTMD------------------------IGG 338
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 731 DEVLSRIEKLSEVNPMLGFRGCRLGISYPELTEMQARAIFEAAASMQDQgvtvipeIMVPLVGTPQELGHQVDVIRKVAK 810
Cdd:PRK11177 339 DKELPYMNLPKEENPFLGWRAIRIAMDRKEILHDQLRAILRASAFGKLR-------IMFPMIISVEEVRELKAEIEILKQ 411
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 811 KVFAE-KGHTVSYKVGTMIEIPRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRddvGKFLPIYLakgilqHDPFE--VL 887
Cdd:PRK11177 412 ELRDEgKAFDESIEIGVMVETPAAAVIARHLAKEVDFFSIGTNDLTQYTLAVDR---GNELISHL------YNPMSpsVL 482
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 145333150 888 dqqgvgQLIKMATEKGRAARpslK-VGICGEHGGDPSSVGFFAEAGLDYVSCSPFRVP 944
Cdd:PRK11177 483 ------NLIKQVIDASHAEG---KwTGMCGELAGDERATLLLLGMGLDEFSMSAISIP 531
|
|
| PEP-utilizers |
pfam00391 |
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ... |
507-586 |
4.06e-24 |
|
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.
Pssm-ID: 459796 [Multi-domain] Cd Length: 73 Bit Score: 96.33 E-value: 4.06e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 507 VILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGCSEIRVdenhkvlligdlTINEGEWISMNGSTG 586
Cdd:pfam00391 6 VILVAPDTTPSDTAGLDKAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATI------------LLKEGDLVTVDGSTG 73
|
|
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
527-939 |
6.59e-17 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 85.82 E-value: 6.59e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 527 GILTARGGMTSHAAVVARGWGKCCIAGcSEIRVDENHKVLLI-----GDLTINEG-----EWISMNGSTGEVI-LGKQAL 595
Cdd:PRK11061 345 GVVVRDGAANSHAAILVRALGIPTVMG-ADIQPSLLHQRLLIvdgyrGELLVDPEpvllqEYQRLISEEIELSrLAEDDV 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 596 APPALSPDLEtfmswadairRLKVMANADTPEDAIAARKNGAQGIGLCRTEHMFfgadrikavrkMImavttEQRKASLD 675
Cdd:PRK11061 424 NLPAQLKSGE----------RIKVMLNAGLSAEHEEKLGSRVDGVGLYRTEIPF-----------ML-----QSGFPSEE 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 676 illpYQRSDFEGIFRAMDGLPVTIRLLD----PPLhEFLPegdldnivhelaeetgvkedevlsriekLSEVNPMLGFRG 751
Cdd:PRK11061 478 ----EQVAQYQGMLQMFPDKPVTLRTLDigadKQL-PYMP----------------------------ISEENPCLGWRG 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 752 CRLGISYPELTEMQARAIFEAAASMQDQGvtvipeIMVPLVGTPQELGHQVDVIRKVAKKVFAEKGHTVSY-KVGTMIEI 830
Cdd:PRK11061 525 IRITLDQPEIFLIQVRAMLRANAATGNLS------ILLPMVTSIDEVDEARRLIDRAGREVEEMLGYEIPKpRIGIMIEV 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 831 PRAALIADEIAKEAEFFSFGTNDLTQMTFGYSRDD--VGkflpiylakgilqhDPFEVLdQQGVGQLIKMATEKgrAARP 908
Cdd:PRK11061 599 PSMVFMLPHLASRVDFISVGTNDLTQYLLAVDRNNtrVA--------------SLYDSL-HPAMLRALKMIADE--AEQH 661
|
410 420 430
....*....|....*....|....*....|.
gi 145333150 909 SLKVGICGEHGGDPssVGFFAEAGLDYVSCS 939
Cdd:PRK11061 662 GLPVSLCGEMAGDP--MGALLLIGLGYRHLS 690
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
102-421 |
2.59e-10 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 64.53 E-value: 2.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 102 SLLGGKGANLAEMASIGLSVPPGLTISTEACQQYQIAGKKLpeglwEEILEGLSFIERDIGASLADPSKPLLLSVRSgaa 181
Cdd:PRK06241 17 PLVGGKGANLGELSRAGIPVPEGFCVTTEAYKKFLEQNEEF-----DALLDQLSALKLEDREQIGEISAKIREVIEA--- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 182 ISMPgmmdtvlnlglnDQVVVGLA---AKSGERFAY---------DSfrrfldmfgdvvmgiPHAKFeeklermkerkgv 249
Cdd:PRK06241 89 IEIP------------EDIVEAIAaalSKFGEDHAYavrssataeDL---------------PTASF------------- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 250 kndtdlsAAdlkelveQYKSvYLEAKGqefpsdpKKQLELAIEAVFDSWDSPRANKYRSINQItGLKGT--AVNIQCMVF 327
Cdd:PRK06241 129 -------AG-------QQDT-YLNVIG-------KDAILQHIRKCWASLFTERAVIYRIQNGF-DHRKVymSVVVQKMVF 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 328 gnmGDTSgtGVLFTRNPSTGEKKLYgefLVNAQ---GEDVVAGI--------RTPEDLD-----------------TMKR 379
Cdd:PRK06241 186 ---PEAS--GIMFTADPVTGNRKVL---SIDASfglGEALVSGLvsadtykvREGKIIDktiatkklaiyalkeggTETK 257
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 145333150 380 FMPEAYA-----------ELVENCNILERHYKDMMDIEFTVQEERLWMLQCRA 421
Cdd:PRK06241 258 EIEPEQQksqtltdeqilELARLGRKIEAHFGCPQDIEWCLADGTFYILQSRP 310
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
473-591 |
1.18e-09 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 60.68 E-value: 1.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 473 KVVAKGLPASPGAAVGQVVF--TAEEAEAWHSQGKtvILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCC 550
Cdd:COG3848 210 DVLAKGQGIGRGSVTGKAVVarSAEEALEKFEEGD--ILVVPSTDAEFVPAIEKAAGIITEEGGLTSHAAIVGLELGIPV 287
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 145333150 551 IAGCSeirvdenhkvlliGDLT-INEGEWISMNGSTGEVILG 591
Cdd:COG3848 288 IVGAE-------------GATEiLKDGQVVTVDAERGVVYRG 316
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
478-590 |
5.22e-08 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 56.82 E-value: 5.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 478 GLPASPGAAVGQ--VVFTAEEAEAwhSQGKtvILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGcs 555
Cdd:PRK06241 770 GLPVSSGVVEGRarVILNPEDADL--EKGD--ILVTAFTDPGWTPLFVSIKGLVTEVGGLMTHGAVIAREYGIPAVVG-- 843
|
90 100 110
....*....|....*....|....*....|....*..
gi 145333150 556 eirvdenhkvllIGDLT--INEGEWISMNGSTGEVIL 590
Cdd:PRK06241 844 ------------VENATklIKDGQRIRVDGTEGYVEI 868
|
|
| PRK08296 |
PRK08296 |
hypothetical protein; Provisional |
477-588 |
9.06e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 181362 Cd Length: 603 Bit Score: 49.65 E-value: 9.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 477 KGLPASPGAAVG--QVVFTAEEAEAWHsQGKtvILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCCIAGC 554
Cdd:PRK08296 501 KGFAASPGVVEGpaRVIRSADELSEVQ-EGE--ILVCPVTSPSWAPIFAKIKATVTDIGGVMSHAAIVCREYGLPAVVGT 577
|
90 100 110
....*....|....*....|....*....|....
gi 145333150 555 SeirvdenhkvllIGDLTINEGEWISMNGSTGEV 588
Cdd:PRK08296 578 G------------NATKRIKTGQRLRVDGTKGVV 599
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
473-591 |
1.83e-05 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 48.38 E-value: 1.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145333150 473 KVVAKGLPASPGAAVGQVVF--TAEEAEAWHSQGktvILVRTETSPDDVGGMHAAEGILTARGGMTSHAAVVARGWGKCC 550
Cdd:PRK06354 480 AVVAKGQGIGRKSVSGKARVakTAAEVAKVNEGD---ILVTPSTDADMIPAIEKAAAIITEEGGLTSHAAVVGLRLGIPV 556
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 145333150 551 IAGCSEIrvdenhkvlligDLTINEGEWISMNGSTGEVILG 591
Cdd:PRK06354 557 IVGVKNA------------TSLIKDGQIITVDAARGVVYSG 585
|
|
| |
