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Conserved domains on  [gi|148235204|ref|NP_001078966|]
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solute carrier family 25 member 43 [Mus musculus]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 17-275 7.67e-27

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 107.55  E-value: 7.67e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204  17 LCAGLAGAFSLSLTAPLELATVLAQV---------GKVQSHSlGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSMVQL 87
Cdd:PTZ00169  12 LMGGISAAISKTAVAPIERVKMLIQTqdsipeiksGKVPRYS-GIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204  88 AAYRKFVVLFMDDLGRISQW----SSIVTGSLAGMVSTIVTYPTDLIKTRLM--VQNVLEPSYRGLIHAFSTIYQQEGFL 161
Cdd:PTZ00169  91 AFKDYFKNMFPKYNQKTDFWkffgVNILSGGLAGASSLLIVYPLDFARTRLAsdIGKGGDREFTGLFDCLMKISKQTGFL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204 162 ALYRGVSLTVLGAVPFSAGSLLVYMNLEKVWNGPrdrfshlQNFANVCVAAAVSQTL-------SFPFDTVKRKMQAQSP 234
Cdd:PTZ00169 171 SLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGN-------DKNTNILYKWAVAQTVtilagliSYPFDTVRRRMMMMSG 243

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 148235204 235 ylpHYGGVDVHFSGAADCFRQIVKTQGVLGLWNGLTANLLK 275
Cdd:PTZ00169 244 ---RKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLR 281
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 17-275 7.67e-27

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 107.55  E-value: 7.67e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204  17 LCAGLAGAFSLSLTAPLELATVLAQV---------GKVQSHSlGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSMVQL 87
Cdd:PTZ00169  12 LMGGISAAISKTAVAPIERVKMLIQTqdsipeiksGKVPRYS-GIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204  88 AAYRKFVVLFMDDLGRISQW----SSIVTGSLAGMVSTIVTYPTDLIKTRLM--VQNVLEPSYRGLIHAFSTIYQQEGFL 161
Cdd:PTZ00169  91 AFKDYFKNMFPKYNQKTDFWkffgVNILSGGLAGASSLLIVYPLDFARTRLAsdIGKGGDREFTGLFDCLMKISKQTGFL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204 162 ALYRGVSLTVLGAVPFSAGSLLVYMNLEKVWNGPrdrfshlQNFANVCVAAAVSQTL-------SFPFDTVKRKMQAQSP 234
Cdd:PTZ00169 171 SLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGN-------DKNTNILYKWAVAQTVtilagliSYPFDTVRRRMMMMSG 243

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 148235204 235 ylpHYGGVDVHFSGAADCFRQIVKTQGVLGLWNGLTANLLK 275
Cdd:PTZ00169 244 ---RKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLR 281
Mito_carr pfam00153
Mitochondrial carrier protein;
102-185 3.06e-24

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 94.65  E-value: 3.06e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204  102 GRISQWSSIVTGSLAGMVSTIVTYPTDLIKTRLMVQNVLEPS-YRGLIHAFSTIYQQEGFLALYRGVSLTVLGAVPFSAG 180
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSkGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80


                  ....*
gi 148235204  181 SLLVY 185
Cdd:pfam00153  81 YFGTY 85
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 17-275 7.67e-27

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 107.55  E-value: 7.67e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204  17 LCAGLAGAFSLSLTAPLELATVLAQV---------GKVQSHSlGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSMVQL 87
Cdd:PTZ00169  12 LMGGISAAISKTAVAPIERVKMLIQTqdsipeiksGKVPRYS-GIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204  88 AAYRKFVVLFMDDLGRISQW----SSIVTGSLAGMVSTIVTYPTDLIKTRLM--VQNVLEPSYRGLIHAFSTIYQQEGFL 161
Cdd:PTZ00169  91 AFKDYFKNMFPKYNQKTDFWkffgVNILSGGLAGASSLLIVYPLDFARTRLAsdIGKGGDREFTGLFDCLMKISKQTGFL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204 162 ALYRGVSLTVLGAVPFSAGSLLVYMNLEKVWNGPrdrfshlQNFANVCVAAAVSQTL-------SFPFDTVKRKMQAQSP 234
Cdd:PTZ00169 171 SLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGN-------DKNTNILYKWAVAQTVtilagliSYPFDTVRRRMMMMSG 243

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 148235204 235 ylpHYGGVDVHFSGAADCFRQIVKTQGVLGLWNGLTANLLK 275
Cdd:PTZ00169 244 ---RKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLR 281
Mito_carr pfam00153
Mitochondrial carrier protein;
102-185 3.06e-24

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 94.65  E-value: 3.06e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204  102 GRISQWSSIVTGSLAGMVSTIVTYPTDLIKTRLMVQNVLEPS-YRGLIHAFSTIYQQEGFLALYRGVSLTVLGAVPFSAG 180
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSkGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80


                  ....*
gi 148235204  181 SLLVY 185
Cdd:pfam00153  81 YFGTY 85
Mito_carr pfam00153
Mitochondrial carrier protein;
197-295 2.24e-23

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 92.33  E-value: 2.24e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204  197 DRFSHLQNFANVCVAAAVSQTLSFPFDTVKRKMQAQSPYLPHYGgvdvhfSGAADCFRQIVKTQGVLGLWNGLTANLLKV 276
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKG------RGILDCFKKIYKEEGIRGLYKGLLPNLLRV 74

                          90
                  ....*....|....*....
gi 148235204  277 VPYFGVMFSMFEFCKRIFL 295
Cdd:pfam00153  75 APAAAIYFGTYETLKRLLL 93
Mito_carr pfam00153
Mitochondrial carrier protein;
8-101 3.54e-17

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 75.77  E-value: 3.54e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204    8 GRLTGSQRLLCAGLAGAFSLSLTAPLELATVLAQVGKVQSHS--LGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSMV 85
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSkgRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....*.
gi 148235204   86 QLAAYRKFVVLFMDDL 101
Cdd:pfam00153  81 YFGTYETLKRLLLKKL 96
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 210-294 8.41e-09

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 55.93  E-value: 8.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204 210 VAAAVSQTLSFPFDTVKRKMQAQSPYLPHYGGVDVHFSGAADCFRQIVKTQGVLGLWNGLTANLLKVVPYFGVMFSMFEF 289
Cdd:PTZ00169  16 ISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKVPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNFAFKDY 95


                 ....*
gi 148235204 290 CKRIF 294
Cdd:PTZ00169  96 FKNMF 100
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 109-230 2.35e-06

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 48.38  E-value: 2.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148235204 109 SIVTGSLAGMVSTIVTYPTDLIKTRLMVQNVLepsyrglihAFSTIYQqegflaLYRGVSLTVLGAVPFSAGSLLVYMNL 188
Cdd:PTZ00168   6 NLVTGALSGVIVDAVLYPIDSIKTNIQAKKSF---------SFSDIKK------LYSGILPTLVGTVPASAFFYCFYELS 70

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 148235204 189 EKVWNGPRDRFSHLQNF-ANVCVAAAVSQTLSFPFDTVKRKMQ 230
Cdd:PTZ00168  71 KKLLTEYRENISKTNLYlISTSIAEITACIVRLPFEIVKQNMQ 113
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 100-166 3.66e-03

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 38.37  E-value: 3.66e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 148235204 100 DLGRISQ----WSSIVTGSLAGMVSTIVTYPTDLIKTRlmvQNVLEPSYrglIHAFSTIyQQEGFLALYRG 166
Cdd:PTZ00168 169 DFGKFSKkypsITSAICGGLAGGIAGFLTTPVDVIKSR---QIIYGKSY---IETVTEI-AEEGYLTFYKG 232
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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