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Conserved domains on  [gi|186478771|ref|NP_001117334|]
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T-complex protein 11 [Arabidopsis thaliana]

Protein Classification

TCP11 family protein( domain architecture ID 10530693)

TCP11 family protein similar to Homo sapiens T-complex protein 11 (TCP11) that plays a role in the process of sperm capacitation and acrosome reactions

Gene Ontology:  GO:0007165

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Tcp11 pfam05794
T-complex protein 11; This family consists of several eukaryotic T-complex protein 11 (Tcp11) ...
547-1017 7.27e-61

T-complex protein 11; This family consists of several eukaryotic T-complex protein 11 (Tcp11) related sequences. Tcp11 is only expressed in fertile adult mammalian testes and is thought to be important in sperm function and fertility. The family also contains the yeast Sok1 protein which is known to suppress cyclic AMP-dependent protein kinase mutants.


:

Pssm-ID: 461743  Cd Length: 390  Bit Score: 212.89  E-value: 7.27e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   547 MVNEFLHDGNLNFpggstvKDEEDNLKRRIKETMERAFWDNVMESMKLEKPDYSCISNLMKEVSDELCQMV--PDSWKVE 624
Cdd:pfam05794    1 LRHEIAFDPDFQF------RPNLDGEKGRVKETMAKAYWDALREELEEDPPDYSRLPALLEEIRDILLSLLlpPNRLRQQ 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   625 ITETIDLDILSQLLNSGTLDIDylgKMLEFALATLRKLSAPANDRENESTHRDLLkelhrlceaedesgnfRAVAIVKGI 704
Cdd:pfam05794   75 ISEVLDLELIRQQLEHGVLDLV---KLAEFLASLLKKLCAPMRDEEVKKLVEKIL----------------SVDKLVDGL 135
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   705 RFILEQIQELKREIGIGRIAIMKPFLQGPAgFDYLTKAFEKRY--GPPtqayeSLPVTRRWISTLLSS-KEEWEEHNNTL 781
Cdd:pfam05794  136 RALFEILELMKLDVANHQIRSLRPLLIEQA-VEYERKKFQERLekGPI-----SLPSTRRWLRSAREElLAEADERDPEG 209
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   782 SAlnvverssmgislktggsflSPVNTTSKSTVMDtagqlseckgervdlAVRLGLLKLVNQVAGLTPEVLPETFQLNLF 861
Cdd:pfam05794  210 SN--------------------HPSSGDSSPSPLK---------------ILAQGLLDLLSWSDPVSEEEFPETLLLDHA 254
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   862 RVRDIQAEIQNIIVVTTSLLIWRQMLAKSESETESMAKKL----LELLDG---KEGAGLTEIIE------------TTMS 922
Cdd:pfam05794  255 RLRELRADLRQLVVLAACLLVFKNLLKRDVSSSRSFWKKLksriLALLEDepsSTEALESIALEiarevskslselGLLP 334
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   923 EEDGEKKKMMRGLLGKSLGEGNTVYERVTSCIykaargallagngengkrmvetemkkvggggglkervletARALGVVA 1002
Cdd:pfam05794  335 LMPEATKAWLRGQIQKLLQPSDPVFKLLESEI----------------------------------------AERLARLV 374
                          490
                   ....*....|....*
gi 186478771  1003 CVSVRVHGPWLTQLM 1017
Cdd:pfam05794  375 NVHWRVFGPWYEEIL 389
PTZ00121 super family cl31754
MAEBL; Provisional
5-143 4.19e-04

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.75  E-value: 4.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771    5 KLDELRQAA---KTSVEIRSERERVK-----LGTQVESRVQKAEANRMKI------LKASHQKRACAKERTSQSMMRRMA 70
Cdd:PTZ00121 1303 KADEAKKKAeeaKKADEAKKKAEEAKkkadaAKKKAEEAKKAAEAAKAEAeaaadeAEAAEEKAEAAEKKKEEAKKKADA 1382
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 186478771   71 RESKYKERVRASINQKRVAAEKKR---LGLLEAEKKKARARVQQVRHVANSVSNQREIERSKMRDKLEDKLQRAKR 143
Cdd:PTZ00121 1383 AKKKAEEKKKADEAKKKAEEDKKKadeLKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK 1458
 
Name Accession Description Interval E-value
Tcp11 pfam05794
T-complex protein 11; This family consists of several eukaryotic T-complex protein 11 (Tcp11) ...
547-1017 7.27e-61

T-complex protein 11; This family consists of several eukaryotic T-complex protein 11 (Tcp11) related sequences. Tcp11 is only expressed in fertile adult mammalian testes and is thought to be important in sperm function and fertility. The family also contains the yeast Sok1 protein which is known to suppress cyclic AMP-dependent protein kinase mutants.


Pssm-ID: 461743  Cd Length: 390  Bit Score: 212.89  E-value: 7.27e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   547 MVNEFLHDGNLNFpggstvKDEEDNLKRRIKETMERAFWDNVMESMKLEKPDYSCISNLMKEVSDELCQMV--PDSWKVE 624
Cdd:pfam05794    1 LRHEIAFDPDFQF------RPNLDGEKGRVKETMAKAYWDALREELEEDPPDYSRLPALLEEIRDILLSLLlpPNRLRQQ 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   625 ITETIDLDILSQLLNSGTLDIDylgKMLEFALATLRKLSAPANDRENESTHRDLLkelhrlceaedesgnfRAVAIVKGI 704
Cdd:pfam05794   75 ISEVLDLELIRQQLEHGVLDLV---KLAEFLASLLKKLCAPMRDEEVKKLVEKIL----------------SVDKLVDGL 135
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   705 RFILEQIQELKREIGIGRIAIMKPFLQGPAgFDYLTKAFEKRY--GPPtqayeSLPVTRRWISTLLSS-KEEWEEHNNTL 781
Cdd:pfam05794  136 RALFEILELMKLDVANHQIRSLRPLLIEQA-VEYERKKFQERLekGPI-----SLPSTRRWLRSAREElLAEADERDPEG 209
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   782 SAlnvverssmgislktggsflSPVNTTSKSTVMDtagqlseckgervdlAVRLGLLKLVNQVAGLTPEVLPETFQLNLF 861
Cdd:pfam05794  210 SN--------------------HPSSGDSSPSPLK---------------ILAQGLLDLLSWSDPVSEEEFPETLLLDHA 254
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   862 RVRDIQAEIQNIIVVTTSLLIWRQMLAKSESETESMAKKL----LELLDG---KEGAGLTEIIE------------TTMS 922
Cdd:pfam05794  255 RLRELRADLRQLVVLAACLLVFKNLLKRDVSSSRSFWKKLksriLALLEDepsSTEALESIALEiarevskslselGLLP 334
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   923 EEDGEKKKMMRGLLGKSLGEGNTVYERVTSCIykaargallagngengkrmvetemkkvggggglkervletARALGVVA 1002
Cdd:pfam05794  335 LMPEATKAWLRGQIQKLLQPSDPVFKLLESEI----------------------------------------AERLARLV 374
                          490
                   ....*....|....*
gi 186478771  1003 CVSVRVHGPWLTQLM 1017
Cdd:pfam05794  375 NVHWRVFGPWYEEIL 389
PTZ00121 PTZ00121
MAEBL; Provisional
5-143 4.19e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.75  E-value: 4.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771    5 KLDELRQAA---KTSVEIRSERERVK-----LGTQVESRVQKAEANRMKI------LKASHQKRACAKERTSQSMMRRMA 70
Cdd:PTZ00121 1303 KADEAKKKAeeaKKADEAKKKAEEAKkkadaAKKKAEEAKKAAEAAKAEAeaaadeAEAAEEKAEAAEKKKEEAKKKADA 1382
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 186478771   71 RESKYKERVRASINQKRVAAEKKR---LGLLEAEKKKARARVQQVRHVANSVSNQREIERSKMRDKLEDKLQRAKR 143
Cdd:PTZ00121 1383 AKKKAEEKKKADEAKKKAEEDKKKadeLKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK 1458
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
3-156 4.50e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 40.63  E-value: 4.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771    3 LAKLDELRQAAKtsvEIRSERERvklgtqvESRVQKAEANRMKILKASHQKRACAkertsqsmMRRMARESKYKERVRAS 82
Cdd:COG2268   191 RRKIAEIIRDAR---IAEAEAER-------ETEIAIAQANREAEEAELEQEREIE--------TARIAEAEAELAKKKAE 252
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 186478771   83 INQKRVAAEKKRlgllEAEKKKARARVQQ-VRHVANSVSNQREIE-RSKMRDKLEDKLQRAKRYRSEFLRQRRRQR 156
Cdd:COG2268   253 ERREAETARAEA----EAAYEIAEANAEReVQRQLEIAEREREIElQEKEAEREEAELEADVRKPAEAEKQAAEAE 324
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
4-157 5.58e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.49  E-value: 5.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771     4 AKLDELRQAAKTSVEIRSERE--RVKL-----GTQVESRVQKAEANRMKILKASHQKRacakERTSQSMMRRMARESKYK 76
Cdd:pfam17380  427 AEQEEARQREVRRLEEERAREmeRVRLeeqerQQQVERLRQQEEERKRKKLELEKEKR----DRKRAEEQRRKILEKELE 502
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771    77 ERVRASINQKRvaaEKKRLGLLEAEKKKARARVQQVRHVANSVSNQREIERskmRDKLEDKLQRAKRYRSEfLRQRRRQR 156
Cdd:pfam17380  503 ERKQAMIEEER---KRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEE---RRRIQEQMRKATEERSR-LEAMERER 575

                   .
gi 186478771   157 D 157
Cdd:pfam17380  576 E 576
 
Name Accession Description Interval E-value
Tcp11 pfam05794
T-complex protein 11; This family consists of several eukaryotic T-complex protein 11 (Tcp11) ...
547-1017 7.27e-61

T-complex protein 11; This family consists of several eukaryotic T-complex protein 11 (Tcp11) related sequences. Tcp11 is only expressed in fertile adult mammalian testes and is thought to be important in sperm function and fertility. The family also contains the yeast Sok1 protein which is known to suppress cyclic AMP-dependent protein kinase mutants.


Pssm-ID: 461743  Cd Length: 390  Bit Score: 212.89  E-value: 7.27e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   547 MVNEFLHDGNLNFpggstvKDEEDNLKRRIKETMERAFWDNVMESMKLEKPDYSCISNLMKEVSDELCQMV--PDSWKVE 624
Cdd:pfam05794    1 LRHEIAFDPDFQF------RPNLDGEKGRVKETMAKAYWDALREELEEDPPDYSRLPALLEEIRDILLSLLlpPNRLRQQ 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   625 ITETIDLDILSQLLNSGTLDIDylgKMLEFALATLRKLSAPANDRENESTHRDLLkelhrlceaedesgnfRAVAIVKGI 704
Cdd:pfam05794   75 ISEVLDLELIRQQLEHGVLDLV---KLAEFLASLLKKLCAPMRDEEVKKLVEKIL----------------SVDKLVDGL 135
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   705 RFILEQIQELKREIGIGRIAIMKPFLQGPAgFDYLTKAFEKRY--GPPtqayeSLPVTRRWISTLLSS-KEEWEEHNNTL 781
Cdd:pfam05794  136 RALFEILELMKLDVANHQIRSLRPLLIEQA-VEYERKKFQERLekGPI-----SLPSTRRWLRSAREElLAEADERDPEG 209
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   782 SAlnvverssmgislktggsflSPVNTTSKSTVMDtagqlseckgervdlAVRLGLLKLVNQVAGLTPEVLPETFQLNLF 861
Cdd:pfam05794  210 SN--------------------HPSSGDSSPSPLK---------------ILAQGLLDLLSWSDPVSEEEFPETLLLDHA 254
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   862 RVRDIQAEIQNIIVVTTSLLIWRQMLAKSESETESMAKKL----LELLDG---KEGAGLTEIIE------------TTMS 922
Cdd:pfam05794  255 RLRELRADLRQLVVLAACLLVFKNLLKRDVSSSRSFWKKLksriLALLEDepsSTEALESIALEiarevskslselGLLP 334
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   923 EEDGEKKKMMRGLLGKSLGEGNTVYERVTSCIykaargallagngengkrmvetemkkvggggglkervletARALGVVA 1002
Cdd:pfam05794  335 LMPEATKAWLRGQIQKLLQPSDPVFKLLESEI----------------------------------------AERLARLV 374
                          490
                   ....*....|....*
gi 186478771  1003 CVSVRVHGPWLTQLM 1017
Cdd:pfam05794  375 NVHWRVFGPWYEEIL 389
PTZ00121 PTZ00121
MAEBL; Provisional
5-143 4.19e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.75  E-value: 4.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771    5 KLDELRQAA---KTSVEIRSERERVK-----LGTQVESRVQKAEANRMKI------LKASHQKRACAKERTSQSMMRRMA 70
Cdd:PTZ00121 1303 KADEAKKKAeeaKKADEAKKKAEEAKkkadaAKKKAEEAKKAAEAAKAEAeaaadeAEAAEEKAEAAEKKKEEAKKKADA 1382
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 186478771   71 RESKYKERVRASINQKRVAAEKKR---LGLLEAEKKKARARVQQVRHVANSVSNQREIERSKMRDKLEDKLQRAKR 143
Cdd:PTZ00121 1383 AKKKAEEKKKADEAKKKAEEDKKKadeLKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK 1458
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2-157 8.30e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.49  E-value: 8.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771    2 RLAKLDELRQAAKTSVEIRSER-ERVKLGTQVESRVQKAEANRMKILKASHQKRACAKERTSQ-SMMRRMARESKYK-ER 78
Cdd:PRK02224  476 RVEELEAELEDLEEEVEEVEERlERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERaEELRERAAELEAEaEE 555
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771   79 VRASINQKRVAAEKKR--LGLLEAEKKKARARVQQVRHVANSVS----NQREIERskMRDKLEDkLQRAKRYRSEFLRQR 152
Cdd:PRK02224  556 KREAAAEAEEEAEEAReeVAELNSKLAELKERIESLERIRTLLAaiadAEDEIER--LREKREA-LAELNDERRERLAEK 632

                  ....*
gi 186478771  153 RRQRD 157
Cdd:PRK02224  633 RERKR 637
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
3-156 4.50e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 40.63  E-value: 4.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771    3 LAKLDELRQAAKtsvEIRSERERvklgtqvESRVQKAEANRMKILKASHQKRACAkertsqsmMRRMARESKYKERVRAS 82
Cdd:COG2268   191 RRKIAEIIRDAR---IAEAEAER-------ETEIAIAQANREAEEAELEQEREIE--------TARIAEAEAELAKKKAE 252
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 186478771   83 INQKRVAAEKKRlgllEAEKKKARARVQQ-VRHVANSVSNQREIE-RSKMRDKLEDKLQRAKRYRSEFLRQRRRQR 156
Cdd:COG2268   253 ERREAETARAEA----EAAYEIAEANAEReVQRQLEIAEREREIElQEKEAEREEAELEADVRKPAEAEKQAAEAE 324
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
4-157 5.58e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.49  E-value: 5.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771     4 AKLDELRQAAKTSVEIRSERE--RVKL-----GTQVESRVQKAEANRMKILKASHQKRacakERTSQSMMRRMARESKYK 76
Cdd:pfam17380  427 AEQEEARQREVRRLEEERAREmeRVRLeeqerQQQVERLRQQEEERKRKKLELEKEKR----DRKRAEEQRRKILEKELE 502
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186478771    77 ERVRASINQKRvaaEKKRLGLLEAEKKKARARVQQVRHVANSVSNQREIERskmRDKLEDKLQRAKRYRSEfLRQRRRQR 156
Cdd:pfam17380  503 ERKQAMIEEER---KRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEE---RRRIQEQMRKATEERSR-LEAMERER 575

                   .
gi 186478771   157 D 157
Cdd:pfam17380  576 E 576
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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