|
Name |
Accession |
Description |
Interval |
E-value |
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
24-338 |
0e+00 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 588.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 24 IDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSEKRKMVFHITT 103
Cdd:TIGR02238 1 IDKLQAHGINAADIKKLKSAGICTVNGVIMTTRRALCKIKGLSEAKVDKIKEAASKIINPGFITAFEISQKRKKVLKITT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 104 GSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHDA 183
Cdd:TIGR02238 81 GSQALDGILGGGIESMSITEVFGEFRCGKTQLSHTLCVTAQLPREMGGGNGKVAYIDTEGTFRPDRIRAIAERFGVDPDA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 184 VLDNVLYARAYTSEHQMELLDYVAAKFHEEagIFKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVA 263
Cdd:TIGR02238 161 VLDNILYARAYTSEHQMELLDYLAAKFSEE--PFRLLIVDSIMALFRVDFSGRGELSERQQKLAQMLSRLNKISEEFNVA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 194474078 264 VFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITTGGIGDA 338
Cdd:TIGR02238 239 VFVTNQVQADPGATMTFIADPKKPIGGHVLAHASTTRILLRKGRGEERVAKLYDSPDMPEAEASFQITEGGIADA 313
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
2-340 |
0e+00 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 546.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 2 KEDQVVQEESGfqDEEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLI 81
Cdd:PTZ00035 3 ESQNEQQEEEE--EEEAEGFQEIEKLQSAGINAADIKKLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAASKLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 82 EPGFLTAFQYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDT 161
Cdd:PTZ00035 81 PMGFISATEYLEARKNIIRITTGSTQLDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 162 ENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIVDSIMALFRVDFSGRGELAE 241
Cdd:PTZ00035 161 EGTFRPERIVQIAERFGLDPEDVLDNIAYARAYNHEHQMQLLSQAAAKMAEER--FALLIVDSATALFRVDYSGRGELAE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 242 RQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEM 321
Cdd:PTZ00035 239 RQQHLGKFLRALQKLADEFNVAVVITNQVMADVDGASMFVADPKKPIGGHIIAHASTTRLSLRKGRGEQRICKIYDSPNL 318
|
330
....*....|....*....
gi 194474078 322 PENEATFAITTGGIGDAKE 340
Cdd:PTZ00035 319 PESEAVFAISEGGIIDAKD 337
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
101-337 |
0e+00 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 519.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRFNVD 180
Cdd:cd19514 1 ISTGSTELDKLLGGGIESMSITEVFGEFRTGKTQLSHTLCVTAQLPGSMGGGGGKVAYIDTEGTFRPDRIRPIAERFGVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 181 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgIFKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 260
Cdd:cd19514 81 HDAVLDNILYARAYTSEHQMELLDYVAAKFHEEA-VFRLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194474078 261 NVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITTGGIGD 337
Cdd:cd19514 160 NVAVFITNQVTADPGAAMTFQADPKKPIGGHILAHASTTRISLRKGRGEERIAKIYDSPDLPENEATFAITAGGIAD 236
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
5-340 |
3.24e-168 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 471.95 E-value: 3.24e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 5 QVVQEESGfqDEEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPG 84
Cdd:PLN03187 14 QLVEAEEV--DEEEDLFESIDKLISQGINAGDVKKLQDAGIYTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAEKLLNQG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 85 FLTAFQYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENT 164
Cdd:PLN03187 92 FITGSDALLKRKSVVRITTGSQALDELLGGGIETRCITEAFGEFRSGKTQLAHTLCVTTQLPTEMGGGNGKVAYIDTEGT 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 165 FRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIVDSIMALFRVDFSGRGELAERQQ 244
Cdd:PLN03187 172 FRPDRIVPIAERFGMDADAVLDNIIYARAYTYEHQYNLLLGLAAKMAEEP--FRLLIVDSVIALFRVDFTGRGELAERQQ 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 245 KLAQMLSRLQKISEEYNVAVFVTNQMTADPGAtMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPEN 324
Cdd:PLN03187 250 KLAQMLSRLTKIAEEFNVAVYMTNQVIADPGG-GMFISDPKKPAGGHVLAHAATIRLMLRKGKGEQRVCKVFDAPNLPEA 328
|
330
....*....|....*.
gi 194474078 325 EATFAITTGGIGDAKE 340
Cdd:PLN03187 329 EAEFQITSGGIMDAKD 344
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
101-336 |
1.82e-158 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 442.74 E-value: 1.82e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRFNVD 180
Cdd:cd01123 1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAIYIDTEGTFRPERLRAIAQRFGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 181 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEagIFKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 260
Cdd:cd01123 81 PDDVLDNVAYARAFNSDHQTQLLDQAAAMMVES--RFKLLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEF 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 194474078 261 NVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITTGGIG 336
Cdd:cd01123 159 GVAVVVTNQVVAQVDGAMMFAADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITADGVG 234
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
24-340 |
1.85e-153 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 433.38 E-value: 1.85e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 24 IDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSEKRKMVFHITT 103
Cdd:TIGR02239 1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 104 GSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHDA 183
Cdd:TIGR02239 81 GSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLNPED 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 184 VLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVA 263
Cdd:TIGR02239 161 VLDNVAYARAYNTDHQLQLLQQAAAMMSESR--FALLIVDSATALYRTDFSGRGELSARQMHLARFLRSLQRLADEFGVA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 194474078 264 VFVTNQMTADP-GATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITTGGIGDAKE 340
Cdd:TIGR02239 239 VVITNQVVAQVdGAGSMFAGDPKKPIGGNIMAHASTTRLSLRKGRGEQRICKIYDSPCLPESEAMFAIYEDGIGDPKE 316
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
1-340 |
9.10e-153 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 432.62 E-value: 9.10e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 1 MKEDQVVQEESGFQDEEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKL 80
Cdd:PLN03186 5 VAAAAAQAMQEEEEEEAAHGPFPIEQLQASGIAALDIKKLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEAASKL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 81 IEPGFLTAFQYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFID 160
Cdd:PLN03186 85 VPLGFTTASQLHAQRQEIIQITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTLCVTCQLPLDQGGGEGKAMYID 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 161 TENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIVDSIMALFRVDFSGRGELA 240
Cdd:PLN03186 165 TEGTFRPQRLIQIAERFGLNGADVLENVAYARAYNTDHQSELLLEAASMMAETR--FALMIVDSATALYRTEFSGRGELS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 241 ERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGAtMTFQADPK-KPIGGHILAHASTTRISLRKGRGELRIAKIYDSP 319
Cdd:PLN03186 243 ARQMHLGKFLRSLQRLADEFGVAVVITNQVVAQVDG-SAFFAGPQlKPIGGNIMAHASTTRLALRKGRGENRICKVISSP 321
|
330 340
....*....|....*....|.
gi 194474078 320 EMPENEATFAITTGGIGDAKE 340
Cdd:PLN03186 322 CLPEAEARFSISSEGVTDVKD 342
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
84-338 |
1.89e-152 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 428.26 E-value: 1.89e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 84 GFLTAFQYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTEN 163
Cdd:pfam08423 2 GFTTATELHQRRSELIQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 164 TFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIVDSIMALFRVDFSGRGELAERQ 243
Cdd:pfam08423 82 TFRPERLVAIAERYGLDPEDVLDNVAYARAYNSEHQMQLLQQAAAMMSESR--FALLIVDSATALYRTDFSGRGELAERQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 244 QKLAQMLSRLQKISEEYNVAVFVTNQMTADP-GATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMP 322
Cdd:pfam08423 160 QHLAKFLRTLQRLADEFGVAVVITNQVVAQVdGAAGMFSGDPKKPIGGHIMAHASTTRLSLRKGRGEQRICKIYDSPCLP 239
|
250
....*....|....*.
gi 194474078 323 ENEATFAITTGGIGDA 338
Cdd:pfam08423 240 ESEAVFAIGSGGIIDP 255
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
101-337 |
1.69e-136 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 387.06 E-value: 1.69e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRFNVD 180
Cdd:cd19513 1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 181 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 260
Cdd:cd19513 81 GEDVLDNVAYARAYNTDHQMQLLIQASAMMAESR--YALLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEF 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194474078 261 NVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITTGGIGD 337
Cdd:cd19513 159 GVAVVITNQVVAQVDGAAMFAGDPKKPIGGNIMAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITEDGIGD 235
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
23-338 |
1.37e-125 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 362.66 E-value: 1.37e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 23 DIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIE-PGFLTAFQYSEKRKMVFHI 101
Cdd:PRK04301 5 EKDLEDLPGVGPATAEKLREAGYDTVEAIAVASPKELSEAAGIGESTAAKIIEAAREAADiGGFETALEVLERRKNVGKI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 102 TTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRFNVDH 181
Cdd:PRK04301 85 TTGSKELDELLGGGIETQSITEFYGEFGSGKTQICHQLAVNVQLPEEKGGLEGKAVYIDTEGTFRPERIEQMAEALGLDP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 182 DAVLDNVLYARAYTSEHQMELLDYvAAKFHEEAGIFKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYN 261
Cdd:PRK04301 165 DEVLDNIHVARAYNSDHQMLLAEK-AEELIKEGENIKLVIVDSLTAHFRAEYVGRGNLAERQQKLNKHLHDLLRLADLYN 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194474078 262 VAVFVTNQMTADPGAtmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITTGGIGDA 338
Cdd:PRK04301 244 AAVVVTNQVMARPDA---FFGDPTQPIGGHILGHTATFRIYLRKSKGNKRIARLVDSPHLPEGEAVFRITEEGIRDA 317
|
|
| recomb_radA |
TIGR02236 |
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
31-337 |
1.47e-118 |
|
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 344.42 E-value: 1.47e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 31 GINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPG-FLTAFQYSEKRKMVFHITTGSQEFD 109
Cdd:TIGR02236 6 GVGPATAEKLREAGYDTFEAIAVASPKELSEIAGISEGTAAKIIQAARKAADLGgFETADDVLERRKTIGKITTGSKELD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 110 KLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVL 189
Cdd:TIGR02236 86 ELLGGGIETQAITEVFGEFGSGKTQICHQLAVNVQLPEEKGGLGGKAVYIDTENTFRPERIMQMAEARGLDPDEVLKNIY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 190 YARAYTSEHQMELLDYVAAKFHEEAGIFKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQ 269
Cdd:TIGR02236 166 VARAYNSNHQMLLVEKAEDLIKELNNPVKLLIVDSLTSHFRAEYVGRGALAERQQKLNKHLHDLLRLADLYNAAVVVTNQ 245
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 194474078 270 MTADPGAtmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITTGGIGD 337
Cdd:TIGR02236 246 VMARPDA---FFGDPTRPIGGHILGHAATFRVYLRKGKGDKRIARLVDSPHLPEGEAVFRITEKGIED 310
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
101-337 |
5.39e-109 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 317.38 E-value: 5.39e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRFNVD 180
Cdd:cd19515 1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPPEEGGLNGKAVYIDTENTFRPERIMQMAKALGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 181 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIfKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 260
Cdd:cd19515 81 PDEVLDNIYVARAYNSNHQMLLVEKAEDLIKEGNNI-KLLIVDSLTSHFRAEYVGRGTLAERQQKLNKHLHDLHRLADLY 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194474078 261 NVAVFVTNQMTADPGAtmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITTGGIGD 337
Cdd:cd19515 160 NIAVLVTNQVMAKPDA---FFGDPTQAIGGHILGHAATFRVYLRKGKGGKRIARLVDSPHLPEGEAVFRITEKGIED 233
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
121-305 |
1.89e-46 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 155.97 E-value: 1.89e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 121 ITEAFGEFRTGKTQLSHTLCVTAQLpgadgySGGKIIFIDTENTFRPDRLRDIA---DRFNVDHDAVLDNVLYARAYTSE 197
Cdd:cd01393 3 ITEIYGPPGSGKTQLALQLAANALL------LGGGVVWIDTEGAFPPSRLVQILeasPSSELELAEALSRLLYFRPPDTL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 198 HQMELLDYvaakfHEEAGI----FKLLIVDSIMALFRVDF----SGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQ 269
Cdd:cd01393 77 AHLLALDS-----LPESLFpppnTSLVVVDSVSALFRKAFprggDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQ 151
|
170 180 190
....*....|....*....|....*....|....*.
gi 194474078 270 MTADPGAtmTFQADPKKPIGGHILAHASTTRISLRK 305
Cdd:cd01393 152 VTTKIRG--GSGASLVPPALGNTWEHSVSTRLLLYR 185
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
97-335 |
6.72e-42 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 145.39 E-value: 6.72e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 97 MVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTqlshTLCVTAQLPGADgySGGKIIFIDTENtFRPDRLRDIADR 176
Cdd:PRK09361 1 MDERLPTGCKMLDELLGGGFERGTITQIYGPPGSGKT----NICLQLAVEAAK--NGKKVIYIDTEG-LSPERFKQIAGE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 177 fnvDHDAVLDNVLYARAYTSEHQ----MELLDYVAAKFheeagifKLLIVDSIMALFRVDFSGRGELAERQQKLAQMLSR 252
Cdd:PRK09361 74 ---DFEELLSNIIIFEPSSFEEQseaiRKAEKLAKENV-------GLIVLDSATSLYRLELEDEEDNSKLNRELGRQLTH 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 253 LQKISEEYNVAVFVTNQMTADPGATMTfqadpkKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENE-ATFAIT 331
Cdd:PRK09361 144 LLKLARKHDLAVVITNQVYSDIDSDGL------RPLGGHTLEHWSKTILRLEKFRNGKRRATLEKHRSRPEGEsAEFRIT 217
|
....
gi 194474078 332 TGGI 335
Cdd:PRK09361 218 DRGI 221
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
108-305 |
1.51e-40 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 142.43 E-value: 1.51e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 108 FDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIADRF-----NVDHD 182
Cdd:cd19491 1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQLALTVQLPRELGGLGGGAVYICTESSFPSKRLQQLASSLpkryhLEKAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 183 AVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIfKLLIVDSIMALFRVDF-SGRGELAERQQKLAQMLSRLQKISEEYN 261
Cdd:cd19491 81 NFLDNIFVEHVADLETLEHCLNYQLPALLERGPI-RLVVIDSIAALFRSEFdTSRSDLVERAKYLRRLADHLKRLADKYN 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 194474078 262 VAVFVTNQMTADPGA---------------TMTFQADP----KKPIGGHILAHASTTRISLRK 305
Cdd:cd19491 160 LAVVVVNQVTDRFDSssdasglgvldylsqFSSFSGGVsgnrKVPALGLTWANLVNTRLMLSR 222
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
101-335 |
6.08e-38 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 134.75 E-value: 6.08e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAqlpgadGYSGGKIIFIDTENtFRPDRLRDIA-DRFnv 179
Cdd:cd01394 1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKTNICLQLAVEA------AKQGKKVVYIDTEG-LSPERFQQIAgERF-- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 180 dhDAVLDNVLYARAYTSEHQMELLDYvAAKFhEEAGIFKLLIVDSIMALFRVDfsgRGELAERQQKLAQMLSRLQKISEE 259
Cdd:cd01394 72 --ESIASNIIVFEPYSFDEQGVAIQE-AEKL-LKSDKVDLVVVDSATALYRLE---LGDDSEANRELSRQMSKLLSIARK 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194474078 260 YNVAVFVTNQMTADpgatmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENE-ATFAITTGGI 335
Cdd:cd01394 145 YDIPVVITNQVYSD------IDDDRLKPVGGTLLEHWSKAIIRLEKSPPGLRRATLEKHRSRPEGQsAGFRITDRGI 215
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
109-319 |
6.29e-34 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 124.35 E-value: 6.29e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 109 DKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFRPDRLRDIA-----------DRF 177
Cdd:cd19493 1 DTALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKGGLDGGVLYIDTESKFSAERLAEIAearfpeafsgfMEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 178 NVDHDAVLDNVLYARAYTSEhqmELLDYVAAKFHE--EAGIfKLLIVDSIMALFRVDFSG-RGELAERQQKLAQMLSRLQ 254
Cdd:cd19493 81 NERAEEMLKRVAVVRVTTLA---QLLERLPNLEEHilSSGV-RLVVIDSIAALVRREFGGsDGEVTERHNALAREASSLK 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 194474078 255 KISEEYNVAVFVTNQMTADPGATMTFQADPKKPIgGHILAHASTTRISLRKGRG-ELRIAKIYDSP 319
Cdd:cd19493 157 RLAEEFRIAVLVTNQATTHFGDAGDGSSGVTAAL-GDAWAHAVNTRLRLERCLLqLRRVLEIVKSP 221
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
109-335 |
7.22e-31 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 115.98 E-value: 7.22e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 109 DKLLGGGIESMAITEAFGEFRTGKTqlshTLCVTAQLPGADgySGGKIIFIDTENtFRPDRLRDIADRfnvDHDAVLDNV 188
Cdd:TIGR02237 2 DELLGGGVERGTITQIYGPPGSGKT----NICMILAVNAAR--QGKKVVYIDTEG-LSPERFKQIAED---RPERALSNF 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 189 LYARAYTSEHQMELLDYvAAKFHEEAGiFKLLIVDSIMALFRVDFSGRGELAERQqkLAQMLSRLQKISEEYNVAVFVTN 268
Cdd:TIGR02237 72 IVFEVFDFDEQGVAIQK-TSKFIDRDS-ASLVVVDSFTALYRLELSDDRISRNRE--LARQLTLLLSLARKKNLAVVITN 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 194474078 269 QMTADPGatmtfqADPKKPIGGHILAHASTTRISLRKGRGElRIAKIYDSPEMPENE-ATFAITTGGI 335
Cdd:TIGR02237 148 QVYTDVN------NGTLRPLGGHLLEHWSKVILRLEKFRGR-RLATLEKHRSRPEGEsVYFRITDDGI 208
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
71-306 |
4.66e-29 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 114.50 E-value: 4.66e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 71 EKIKEAANKLIEPGFL--TAFQYSEKRKM-VFHITTGSQEFDKLLG-GGIESMAITEAFGEFRTGKTQLSHTLCVTAQLp 146
Cdd:COG0468 11 EKALEAALSQIEKQFGkgSIMRLGDKARQdVEVISTGSLALDIALGvGGLPRGRIVEIYGPESSGKTTLALHAIAEAQK- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 147 gadgySGGKIIFIDTENTFRPDRlrdiADRFNVDhdavLDNVLYARAYTSEHQMELLDYVAakfheEAGIFKLLIVDSIM 226
Cdd:COG0468 90 -----AGGIAAFIDAEHALDPEY----AKKLGVD----IDNLLVSQPDTGEQALEIAETLV-----RSGAVDLIVVDSVA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 227 ALF-RVDFSGR---GELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGatMTFqADPKKPIGGHILAHASTTRIS 302
Cdd:COG0468 152 ALVpKAEIEGEmgdSHVGLQARLMSQALRKLTGAISKSNTTVIFINQLREKIG--VMF-GNPETTTGGNALKFYASVRLD 228
|
....
gi 194474078 303 LRKG 306
Cdd:COG0468 229 IRRI 232
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
121-319 |
3.44e-28 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 107.70 E-value: 3.44e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 121 ITEAFGEFRTGKTQLSHTLCVTAQLPGADGYSGGKIIFIDTENTFrpdrlrdiadrfnvdhdavldNVLYARAYTSEHQM 200
Cdd:cd19492 3 ITEICGVPGVGKTQLCMQLAVNVQIPKCFGGLAGEAIYIDTEGSF---------------------NIHYFRVHDYVELL 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 201 ELLDYVAAKFHEEAGIfKLLIVDSIMALFRVDFSGrgeLAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTF 280
Cdd:cd19492 62 ALINSLPKFLEDHPKV-KLIVVDSIAFPFRHDFDD---LAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTTKISEDGQS 137
|
170 180 190
....*....|....*....|....*....|....*....
gi 194474078 281 QAdpkKPIGGHILAHASTTRISLRKGRGElRIAKIYDSP 319
Cdd:cd19492 138 QL---VPALGESWSHACTTRLFLTWDEKQ-RFAHLYKSP 172
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
113-305 |
1.55e-20 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 88.08 E-value: 1.55e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 113 GGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLpgadgYSGGKIIFIDTENTFRPDRLRDIAD-RFNVDH--DAVLDNVL 189
Cdd:cd19489 1 GGGLRTGEITELVGESSSGKTQLCLTAAANVAS-----RSGQNVLYIDTKSSFSARRLAQILKsRAQDAEeiDKALQRIR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 190 YARAYTSEHQMELLDYVAAKFHEE----AGIFKLLIVDSIMALFRVDFSGrgelAERQQKLAQM--LSR-LQKISEEYNV 262
Cdd:cd19489 76 VVRVFDPYELLDLLEELRNTLSQQqenlYSRLKLVIIDSLSALISPLLGG----SKHSEGHALLasLARlLKKLAAEYQI 151
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 194474078 263 AVFVTNQMTADPGatMTFQADPkKPIGGHILAHASTTRISLRK 305
Cdd:cd19489 152 AVLVTNLTVRGGD--GGQQGST-KPALGEYWESVPSTRLLLSR 191
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
130-305 |
1.93e-12 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 65.83 E-value: 1.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 130 TGKTQLSHTLCVTAQLPGADG--YSGGK---IIFIDTENTFRPDRLRDIAD-RFN------------VDHDAV----LDN 187
Cdd:cd19490 12 SGKTELLYHLAARCILPSSWGgvPLGGLeaaVVFIDTDGRFDILRLRSILEaRIRaaiqaanssddeEDVEEIarecLQR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 188 VLYARAYTSEH---QMELLDYVAAK--FHEEAGifkLLIVDSIMALFRVDFSGRGELAERQQK----LAQMLSRLQKISE 258
Cdd:cd19490 92 LHIFRCHSSLQllaTLLSLENYLLSlsANPELG---LLLIDSISAFYWQDRFSAELARAAPLLqeaaLRAILRELRRLRR 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 194474078 259 EYNVAVFVTNQM-----------TADPGATMTFQADPKKPIGGHILAHASTTRISLRK 305
Cdd:cd19490 169 RFQLVVIATKQAlfpgksastdnPAANNAVSKASAPSHREYLPRPWQRLVTHRLVLSR 226
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
101-335 |
1.94e-11 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 62.63 E-value: 1.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 101 ITTGSQEFDKLLGGGIE---SMAITeafGEFRTGKTQLSHTLCVTAQLpgadgySGGKIIFIDTENtfRPDRLRDIADRF 177
Cdd:COG0467 2 VPTGIPGLDELLGGGLPrgsSTLLS---GPPGTGKTTLALQFLAEGLR------RGEKGLYVSFEE--SPEQLLRRAESL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 178 NVDHDAVLDN--VLYARAYTSEHQM---ELLDYVAAKFHEEAGifKLLIVDSIMALFRvdfsgrgeLAERQQKLAQMLSR 252
Cdd:COG0467 71 GLDLEEYIESglLRIIDLSPEELGLdleELLARLREAVEEFGA--KRVVIDSLSGLLL--------ALPDPERLREFLHR 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 253 LQKISEEYNVAVFVTNQMTADPGatmtfqadpkkPIGGHILAHASTTRISLRK--GRGE----LRIAKIYDSPeMPENEA 326
Cdd:COG0467 141 LLRYLKKRGVTTLLTSETGGLED-----------EATEGGLSYLADGVILLRYveLGGElrraLSVLKMRGSA-HDRTIR 208
|
....*....
gi 194474078 327 TFAITTGGI 335
Cdd:COG0467 209 EFEITDGGI 217
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
72-326 |
3.36e-09 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 56.64 E-value: 3.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 72 KIKEAANKLIEPGF-------LTafqySEKRKMVFHITTGSQEFDKLLG-GGIESMAITEAFGEFRTGKTQLshTLCVTA 143
Cdd:pfam00154 1 KALEAALKQIEKQFgkgsimkLG----DEKKLDVETISTGSLALDIALGiGGYPKGRIIEIYGPESSGKTTL--ALHAIA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 144 QLPGAdgysGGKIIFIDTENTFRPdrlrDIADRFNVDhdavLDNVLYARAYTSEHQMELLDYVAakfheEAGIFKLLIVD 223
Cdd:pfam00154 75 EAQKA----GGTAAFIDAEHALDP----VYAKKLGVD----IDNLLVSQPDTGEQALEIADMLV-----RSGAIDLIVVD 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 224 SIMALF-RVDFSgrGELAERQQKL-AQMLSR-LQKIS---EEYNVAVFVTNQMTADPGatMTFqADPKKPIGGHILAHAS 297
Cdd:pfam00154 138 SVAALVpKAEIE--GEMGDSHVGLqARLMSQaLRKLTgsiSKSNTTVIFINQIREKIG--VMF-GNPETTTGGRALKFYA 212
|
250 260
....*....|....*....|....*....
gi 194474078 298 TTRISLRkgrgelRIAKIYDSPEMPENEA 326
Cdd:pfam00154 213 SVRLDIR------RIGQIKQGEEVIGNKT 235
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
101-306 |
1.28e-08 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 54.87 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 101 ITTGSQEFDKLLG-GGIESMAITEAFGEFRTGKTQLSHTLCVTAQlpgadgYSGGKIIFIDTENTFRPdrlrDIADRFNV 179
Cdd:cd00983 5 IPTGSLSLDIALGiGGLPRGRIIEIYGPESSGKTTLALHAIAEAQ------KLGGTAAFIDAEHALDP----EYAKKLGV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 180 DhdavLDNVLYARAYTSEHQMELLDYVAakfheEAGIFKLLIVDSIMALF-RVDFSgrGELAERQQKL-AQMLSR-LQKI 256
Cdd:cd00983 75 D----IDNLLVSQPDTGEQALEIADTLI-----RSGAVDLIVVDSVAALVpKAEIE--GEMGDSHVGLqARLMSQaLRKL 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 194474078 257 S---EEYNVAVFVTNQMTADPGatmTFQADPKKPIGGHILAHASTTRISLRKG 306
Cdd:cd00983 144 TgslSKSKTTVIFINQLREKIG---VMFGNPETTTGGNALKFYASVRLDIRRI 193
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
101-335 |
7.41e-08 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 52.27 E-value: 7.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTqlshTLC---VTAQLPgadgySGGKIIFIDTENTfrPDRLRDIADRF 177
Cdd:cd01124 1 VKTGIPGLDELLGGGIPKGSVTLLTGGPGTGKT----LFGlqfLYAGAK-----NGEPGLFFTFEES--PERLLRNAKSF 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 178 NVDHDA--VLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKL--LIVDSIMALFRvdfsgrgeLAERQQKLAQMLSRL 253
Cdd:cd01124 70 GWDFDEmeDEGKLIIVDAPPTEAGRFSLDELLSRILSIIKSFKAkrVVIDSLSGLRR--------AKEDQMRARRIVIAL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 254 QKISEEYNVAVFVTNQMTADPGATMTfqadpkkpiGGHILAHASTTRISLRK--GRGE----LRIAKIYDSPEMPEnEAT 327
Cdd:cd01124 142 LNELRAAGVTTIFTSEMRSFLSSESA---------GGGDVSFIVDGVILLRYveIEGElrrtIRVLKMRGTGHDTG-THP 211
|
....*...
gi 194474078 328 FAITTGGI 335
Cdd:cd01124 212 FEITDKGI 219
|
|
| HHH_5 |
pfam14520 |
Helix-hairpin-helix domain; |
25-79 |
1.70e-04 |
|
Helix-hairpin-helix domain;
Pssm-ID: 434010 [Multi-domain] Cd Length: 57 Bit Score: 39.01 E-value: 1.70e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 194474078 25 DLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANK 79
Cdd:pfam14520 3 ELLSISGIGPKTALALLSAGIGTVEDLAEADVDELAEIPGIGEKTAQRIILELRD 57
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
101-273 |
2.25e-04 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 42.13 E-value: 2.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLShtLCVTAQLPGadgySGGKIIFIDTENTFRPDRLRdiADRFNVD 180
Cdd:cd01121 64 ISTGIGELDRVLGGGLVPGSVVLIGGDPGIGKSTLL--LQVAARLAQ----RGGKVLYVSGEESLSQIKLR--AERLGLG 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 181 HDAvldnvLYARAYTSehqmelLDYVAAKFHEEAgiFKLLIVDSIMALFRVDFSGR-GELAE-RQqkLAQMLSRLQKise 258
Cdd:cd01121 136 SDN-----LYLLAETN------LEAILAEIEELK--PSLVVIDSIQTVYSPELTSSpGSVSQvRE--CAAELLRLAK--- 197
|
170
....*....|....*
gi 194474078 259 EYNVAVFVTNQMTAD 273
Cdd:cd01121 198 ETGIPVFLVGHVTKD 212
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
109-267 |
3.08e-03 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 38.13 E-value: 3.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 109 DKLLGGGIESMAITEAFGEFRTGKT----QLShtLCVTAQLPGADGY---SGGKIIFIDTENTFR--PDRLRDIADRFNV 179
Cdd:pfam13481 23 RWLIKGLLPAGGLGLLAGAPGTGKTtlalDLA--AAVATGKPWLGGPrvpEQGKVLYVSAEGPADelRRRLRAAGADLDL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194474078 180 D-----HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIfKLLIVDSIMALFRVDFSGRGElaerqqkLAQMLSRLQ 254
Cdd:pfam13481 101 ParllfLSLVESLPLFFLDRGGPLLDADVDALEAALEEVEDP-DLVVIDPLARALGGDENSNSD-------VGRLVKALD 172
|
170
....*....|...
gi 194474078 255 KISEEYNVAVFVT 267
Cdd:pfam13481 173 RLARRTGATVLLV 185
|
|
| PRK06067 |
PRK06067 |
flagellar accessory protein FlaH; Validated |
93-166 |
4.78e-03 |
|
flagellar accessory protein FlaH; Validated
Pssm-ID: 180381 Cd Length: 234 Bit Score: 38.03 E-value: 4.78e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 194474078 93 EKRKMVfhITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLpgadgySGGKIIFIDTENTFR 166
Cdd:PRK06067 1 EGKKEI--ISTGNEELDRKLGGGIPFPSLILIEGDHGTGKSVLSQQFVYGALK------QGKKVYVITTENTSK 66
|
|
| |
