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Conserved domains on  [gi|218563737|ref|NP_001136270|]
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chromatin complexes subunit BAP18 isoform 1 [Homo sapiens]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 10446569)

SANT/Myb domain-containing protein binds DNA and may function as a transcription factor

CATH:  1.10.10.60
Gene Ontology:  GO:0006355|GO:0003700|GO:0003677
PubMed:  1631139|8882580

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 41-77 9.62e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


:

Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 38.64  E-value: 9.62e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 218563737   41 KWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIK 77
Cdd:pfam00249   3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCK 39
 
Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 41-77 9.62e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 38.64  E-value: 9.62e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 218563737   41 KWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIK 77
Cdd:pfam00249   3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCK 39
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 41-77 1.47e-03

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 35.24  E-value: 1.47e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 218563737  41 KWTETEIEMLRAAVKRFG-DDLNHISCVIKERTVAQIK 77
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCR 38
 
Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 41-77 9.62e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 38.64  E-value: 9.62e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 218563737   41 KWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIK 77
Cdd:pfam00249   3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCK 39
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 41-77 1.47e-03

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 35.24  E-value: 1.47e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 218563737  41 KWTETEIEMLRAAVKRFG-DDLNHISCVIKERTVAQIK 77
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCR 38
Myb_DNA-bind_7 pfam15963
Myb DNA-binding like;
41-82 6.92e-03

Myb DNA-binding like;


Pssm-ID: 464956 [Multi-domain]  Cd Length: 85  Bit Score: 34.44  E-value: 6.92e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 218563737   41 KWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKATVKR 82
Cdd:pfam15963  10 RWSKEETELFYKALSMFGTDFSLIAQLFPGRTRRQIKLKFKR 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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