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Conserved domains on  [gi|227498253|ref|NP_001153089|]
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phosphatidylinositol N-acetylglucosaminyltransferase subunit P isoform e [Mus musculus]

Protein Classification

phosphatidylinositol N-acetylglucosaminyltransferase subunit P family protein( domain architecture ID 10553518)

phosphatidylinositol N-acetylglucosaminyltransferase subunit P (PIG-P) family protein is part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex which catalyzes the first step of glycosylphosphatidylinositol (GPI) anchor biosynthesis in eukaryotes, the addition of N-acetylglucosamine to phosphatidylinositol; similar to mammalian PIG-P and Saccharomyces cerevisiae Gpi19

EC:  2.4.1.198

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PIG-P pfam08510
PIG-P; PIG-P (phosphatidylinositol N-acetylglucosaminyltransferase subunit P) is an enzyme ...
 84-197 6.09e-57

PIG-P; PIG-P (phosphatidylinositol N-acetylglucosaminyltransferase subunit P) is an enzyme involved in GPI anchor biosynthesis.


:

Pssm-ID: 462498  Cd Length: 121  Bit Score: 175.81  E-value: 6.09e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227498253   84 ERAIYGFVLFLSSQFGFILYLVWAFVPESWLNSLGLTYWPQKYWAVALPVYLLITVVIGYVLLFGINMMSTSPLDSIHTI 163
Cdd:pfam08510   1 TREYYGFVLYILSTLAFVLYLLWAFLPDEWLHSLGITYYPDRYWALAIPAYLLMLMLFTYVAYAAYNLVLTPPLDSLRTI 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 227498253  164 TDNYAKNQQR-------KNYQEDAIPALRDVPISEVNKMFF 197
Cdd:pfam08510  81 TDEYANLVEDdekeeflKEYAEEAIPGVYDLPISEVNRVLY 121
 
Name Accession Description Interval E-value
PIG-P pfam08510
PIG-P; PIG-P (phosphatidylinositol N-acetylglucosaminyltransferase subunit P) is an enzyme ...
 84-197 6.09e-57

PIG-P; PIG-P (phosphatidylinositol N-acetylglucosaminyltransferase subunit P) is an enzyme involved in GPI anchor biosynthesis.


Pssm-ID: 462498  Cd Length: 121  Bit Score: 175.81  E-value: 6.09e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227498253   84 ERAIYGFVLFLSSQFGFILYLVWAFVPESWLNSLGLTYWPQKYWAVALPVYLLITVVIGYVLLFGINMMSTSPLDSIHTI 163
Cdd:pfam08510   1 TREYYGFVLYILSTLAFVLYLLWAFLPDEWLHSLGITYYPDRYWALAIPAYLLMLMLFTYVAYAAYNLVLTPPLDSLRTI 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 227498253  164 TDNYAKNQQR-------KNYQEDAIPALRDVPISEVNKMFF 197
Cdd:pfam08510  81 TDEYANLVEDdekeeflKEYAEEAIPGVYDLPISEVNRVLY 121
 
Name Accession Description Interval E-value
PIG-P pfam08510
PIG-P; PIG-P (phosphatidylinositol N-acetylglucosaminyltransferase subunit P) is an enzyme ...
 84-197 6.09e-57

PIG-P; PIG-P (phosphatidylinositol N-acetylglucosaminyltransferase subunit P) is an enzyme involved in GPI anchor biosynthesis.


Pssm-ID: 462498  Cd Length: 121  Bit Score: 175.81  E-value: 6.09e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 227498253   84 ERAIYGFVLFLSSQFGFILYLVWAFVPESWLNSLGLTYWPQKYWAVALPVYLLITVVIGYVLLFGINMMSTSPLDSIHTI 163
Cdd:pfam08510   1 TREYYGFVLYILSTLAFVLYLLWAFLPDEWLHSLGITYYPDRYWALAIPAYLLMLMLFTYVAYAAYNLVLTPPLDSLRTI 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 227498253  164 TDNYAKNQQR-------KNYQEDAIPALRDVPISEVNKMFF 197
Cdd:pfam08510  81 TDEYANLVEDdekeeflKEYAEEAIPGVYDLPISEVNRVLY 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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