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Conserved domains on  [gi|237681075|ref|NP_001153701|]
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zinc finger protein 275 isoform 2 [Mus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
128-343 2.25e-06

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 49.31  E-value: 2.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 128 PFECEECGKRFKKNAGLSQHLRVHSREKPFDCEECGQSFKANTHLFRHQKLHTSE-------KPFACKACSRDFLDRQEL 200
Cdd:COG5048  226 SLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPL 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 201 LKHQRM--HTG--HLPFDCD--DCGKSFRGVNGLAEHQRIHSGAKPYGCP--HCGKLFRRSS-----ELTKHRRIHTGEK 267
Cdd:COG5048  306 TRHLRSvnHSGesLKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLLnneppQSLQQYKDLKNDK 385

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 268 PYEC--NQCGKAFRQSSSLLEHTRIHSGERPYAC--GDCGKAFRGPSDLIKHRRIHSGLKPYECDKCGKaFRRSSGLSRH 343
Cdd:COG5048  386 KSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNH 464
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 80-152 6.47e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 6.47e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 237681075  80 CRKVFRGVSEFNEHR-NSHAAVAAQPRPGPsraledalEKREQMEREAKPFECEECGKRFKKNAGLSQHlRVHS 152
Cdd:COG5189  357 CNKKYKNQNGLKYHMlHGHQNQKLHENPSP--------EKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH-RKHS 421
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
128-343 2.25e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 49.31  E-value: 2.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 128 PFECEECGKRFKKNAGLSQHLRVHSREKPFDCEECGQSFKANTHLFRHQKLHTSE-------KPFACKACSRDFLDRQEL 200
Cdd:COG5048  226 SLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPL 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 201 LKHQRM--HTG--HLPFDCD--DCGKSFRGVNGLAEHQRIHSGAKPYGCP--HCGKLFRRSS-----ELTKHRRIHTGEK 267
Cdd:COG5048  306 TRHLRSvnHSGesLKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLLnneppQSLQQYKDLKNDK 385

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 268 PYEC--NQCGKAFRQSSSLLEHTRIHSGERPYAC--GDCGKAFRGPSDLIKHRRIHSGLKPYECDKCGKaFRRSSGLSRH 343
Cdd:COG5048  386 KSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNH 464
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 183-235 2.04e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.46  E-value: 2.04e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 237681075 183 KPFaCKACSRDFLDRQELLKHQRMHTghlpFDCDDCGKSFRGVNGLAEH-QRIH 235
Cdd:cd20908    1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHcLQVH 49
zf-H2C2_2 pfam13465
Zinc-finger double domain;
255-280 3.26e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 3.26e-04
                          10        20
                  ....*....|....*....|....*.
gi 237681075  255 ELTKHRRIHTGEKPYECNQCGKAFRQ 280
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 80-152 6.47e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 6.47e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 237681075  80 CRKVFRGVSEFNEHR-NSHAAVAAQPRPGPsraledalEKREQMEREAKPFECEECGKRFKKNAGLSQHlRVHS 152
Cdd:COG5189  357 CNKKYKNQNGLKYHMlHGHQNQKLHENPSP--------EKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH-RKHS 421
PHA00733 PHA00733
hypothetical protein
 240-287 6.46e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.39  E-value: 6.46e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 237681075 240 PYGCPHCGKLFRRSSELTKHRRIHTGEKpyECNQCGKAFRQSSSLLEH 287
Cdd:PHA00733  73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
128-343 2.25e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 49.31  E-value: 2.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 128 PFECEECGKRFKKNAGLSQHLRVHSREKPFDCEECGQSFKANTHLFRHQKLHTSE-------KPFACKACSRDFLDRQEL 200
Cdd:COG5048  226 SLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPL 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 201 LKHQRM--HTG--HLPFDCD--DCGKSFRGVNGLAEHQRIHSGAKPYGCP--HCGKLFRRSS-----ELTKHRRIHTGEK 267
Cdd:COG5048  306 TRHLRSvnHSGesLKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLLnneppQSLQQYKDLKNDK 385

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 268 PYEC--NQCGKAFRQSSSLLEHTRIHSGERPYAC--GDCGKAFRGPSDLIKHRRIHSGLKPYECDKCGKaFRRSSGLSRH 343
Cdd:COG5048  386 KSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
127-282 2.39e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 49.31  E-value: 2.39e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 127 KPFECEECGKRFKKNAGLSQHLR--VHSRE--KPFDCEE--CGQSFKANTHLFRHQKLHTSEKPFACKACSRDFLDRQEL 200
Cdd:COG5048  288 LPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLL 367

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 201 --LKHQRMHTGH-----LPFDCDD--CGKSFRGVNGLAEHQRIHSGAKPYGC--PHCGKLFRRSSELTKHRRIHTGEKPY 269
Cdd:COG5048  368 nnEPPQSLQQYKdlkndKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTNHAPL 447

                        170
                 ....*....|...
gi 237681075 270 ECNQCGKAFRQSS 282
Cdd:COG5048  448 LCSILKSFRRDLD 460
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
130-366 6.26e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.77  E-value: 6.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 130 ECEECGKRFKKNAGLSQHLRVHSREkPFDCEECGQSFKAntHLFRHQKLHTSEKPFACKACSRDFLDRQELLKHQRMHTG 209
Cdd:COG5048  201 ENSPLSSSYSIPSSSSDQNLENSSS-SLPLTTNSQLSPK--SLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNE 277

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 210 H---------LPFDCDDCGKSFRGVNGLAEHQR--IHSG--AKPYGCPH--CGKLFRRSSELTKHRRIHTGEKPYEC--N 272
Cdd:COG5048  278 SdsssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGesLKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklL 357

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 273 QCGKAFRQSS-----SLLEHTRIHSGERPYAC--GDCGKAFRGPSDLIKHRRIHSGLKPYECD--KCGKAFRRSSGLSRH 343
Cdd:COG5048  358 NSSSKFSPLLnneppQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPH 437

                        250       260
                 ....*....|....*....|...
gi 237681075 344 RRIHSGVKRCECSECGRVFKRRS 366
Cdd:COG5048  438 KKIHTNHAPLLCSILKSFRRDLD 460
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
212-292 7.66e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.77  E-value: 7.66e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 212 PFDCDDCGKSFRGVNGLAEHQRIHSGAKPYGCPH--CGKLFRRSSELTKHRRIHTGEKPYECNQCGKAFRQSSSLLEHTR 289
Cdd:COG5048   33 PDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLSS 112


                 ...
gi 237681075 290 IHS 292
Cdd:COG5048  113 SSS 115
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 260-348 2.07e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 46.25  E-value: 2.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681075 260 RRIHT-GEKPYECN--QCGKAFRQSSSLLEHtRIHsgerpyacGDCGKAFRGPSDLIKHRRIHSGLKPYECDKCGKAFRR 336
Cdd:COG5189  340 RMLKVkDGKPYKCPveGCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKN 410

                         90
                 ....*....|..
gi 237681075 337 SSGLSRHRRiHS 348
Cdd:COG5189  411 LNGLKYHRK-HS 421
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
155-221 2.39e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 46.23  E-value: 2.39e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 237681075 155 KPFDCEECGQSFKANTHLFRHQKLHTSEKPFACKACSRD--FLDRQELLKHQRMHTGHLPFDCDDCGKS 221
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPL 100
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 183-235 2.04e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.46  E-value: 2.04e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 237681075 183 KPFaCKACSRDFLDRQELLKHQRMHTghlpFDCDDCGKSFRGVNGLAEH-QRIH 235
Cdd:cd20908    1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHcLQVH 49
zf-H2C2_2 pfam13465
Zinc-finger double domain;
255-280 3.26e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 3.26e-04
                          10        20
                  ....*....|....*....|....*.
gi 237681075  255 ELTKHRRIHTGEKPYECNQCGKAFRQ 280
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 80-152 6.47e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 6.47e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 237681075  80 CRKVFRGVSEFNEHR-NSHAAVAAQPRPGPsraledalEKREQMEREAKPFECEECGKRFKKNAGLSQHlRVHS 152
Cdd:COG5189  357 CNKKYKNQNGLKYHMlHGHQNQKLHENPSP--------EKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH-RKHS 421
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
239-292 1.41e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.45  E-value: 1.41e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 237681075 239 KPYGCPHCGKLFRRSSELTKHRRIHTGEKPYECNQCGKAFRQS--SSLLEHTRIHS 292
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHH 87
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 325-347 3.46e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.58  E-value: 3.46e-03
                          10        20
                  ....*....|....*....|...
gi 237681075  325 YECDKCGKAFRRSSGLSRHRRIH 347
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
311-336 5.56e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 5.56e-03
                          10        20
                  ....*....|....*....|....*.
gi 237681075  311 DLIKHRRIHSGLKPYECDKCGKAFRR 336
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
 240-287 6.46e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.39  E-value: 6.46e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 237681075 240 PYGCPHCGKLFRRSSELTKHRRIHTGEKpyECNQCGKAFRQSSSLLEH 287
Cdd:PHA00733  73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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