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Conserved domains on  [gi|242397490|ref|NP_001156415|]
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protocadherin-16 precursor [Mus musculus]

Protein Classification

cadherin repeat domain-containing protein( domain architecture ID 10182011)

cadherin repeat domain-containing protein similar to Homo sapiens desmoglein-2, which is involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion; cadherins are are calcium-dependent cell adhesion proteins that preferentially interact with themselves in connecting cells

CATH:  2.60.40.60
Gene Ontology:  GO:0007156|GO:0005509
PubMed:  17158740|28268172|27782885|11736639
SCOP:  4007535

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1108-1201 3.00e-38

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 139.37  E-value: 3.00e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1108 VAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKaFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDGGSPPRSA 1187
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGL-FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSS 84

                          90
                  ....*....|....
gi 242397490 1188 TGTVHVAVLDLNDN 1201
Cdd:cd11304    85 TATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1646-1740 5.66e-36

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 132.82  E-value: 5.66e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1646 EYNVILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLP 1722
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYsivSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 242397490 1723 PLLTHITVRVTVEDENDH 1740
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 476-568 1.33e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 128.97  E-value: 1.33e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  476 LPEVALPGSFVVRVTARDPDQGTNGQITYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 555
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                          90
                  ....*....|...
gi 242397490  556 ATVSVALQDVNDN 568
Cdd:cd11304    86 ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 254-352 2.97e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 127.81  E-value: 2.97e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  254 YHAVVSESLAPGSPVLQVFASDADAGANGAVTYEInrRQSEGDGPFSIDAHTGFLRLERPLDFEQRRVHELVVQARDGGA 333
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 242397490  334 HPELGSAFVTVHVRDANDN 352
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2599-2695 2.64e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 122.42  E-value: 2.64e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2599 SYRVTVPEDMPVGAELLHVEASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLSRPLDCETQAQHQLVVQAADPAGT 2678
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 242397490 2679 HFS-LVPVTVEVQDVNDH 2695
Cdd:cd11304    81 PLSsTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1852-1949 2.77e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 122.42  E-value: 2.77e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1852 SYSVEVPEDAPVGTLLLQLQAHDPDDGDNGRVMYYLGAGTA-GAFLLEPTSGELSTATALDREHCASYAFSVTAVDGaAA 1930
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG-GG 79

                          90
                  ....*....|....*....
gi 242397490 1931 GPLSTTVPITITVRDVNDH 1949
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1544-1637 5.74e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 121.27  E-value: 5.74e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1544 RVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGG-DGHFRLHATTGALSVVRPLDREQRAEHVLTVVALDHGSPPR 1622
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*
gi 242397490 1623 SSTQLLTVSVVDVND 1637
Cdd:cd11304    83 SSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1750-1844 4.50e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.87  E-value: 4.50e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1750 SLEVPEGQDP-QTLTTLRASDPDGGLNGQLQYRILDGDSSGAFALDLTSGEFGTMRPLDREVEPAFQLQIEARDGGQPAL 1828
Cdd:cd11304     3 EVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*.
gi 242397490 1829 SATLLVTVTVLDANDH 1844
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2479-2591 3.53e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.56  E-value: 3.53e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2479 HYRVAVSEDLPPGSTLLTLEATDADgSRTHATVDYSIISGNRGRVFQLEPRLaevgdgvgpgpqalGCLVLLEPLDFESL 2558
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDGLFSIDPST--------------GEITTAKPLDREEQ 65

                          90       100       110
                  ....*....|....*....|....*....|...
gi 242397490 2559 TQYNLTVAAADRGQPPRSSAVPVTVTVLDVNDN 2591
Cdd:cd11304    66 SSYTLTVTATDGGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 577-675 3.85e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 110.48  E-value: 3.85e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  577 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGDVCTTRTLDRDQgPSSFDFTVTAIDG 656
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI---VSGNEDGLFSIDPSTGEITTAKPLDREE-QSSYTLTVTATDG 77

                          90       100
                  ....*....|....*....|.
gi 242397490  657 GG--LKSMVYVKVFVADENDN 675
Cdd:cd11304    78 GGppLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 368-462 2.46e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 108.17  E-value: 2.46e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  368 RVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGG--EGHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPP 445
Cdd:cd11304     5 SVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGneDGLFSIDPSTGEIT---TAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*..
gi 242397490  446 LRAEAAFVLHVTDVNDN 462
Cdd:cd11304    82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1218-1306 3.74e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 104.70  E-value: 3.74e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1218 IQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT-GPGSELFSLHPHTGELHTAASLVRAERPHYVLTLSAHDQGSPPRS 1296
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|
gi 242397490 1297 ASLQLLVQVL 1306
Cdd:cd11304    84 STATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2374-2471 9.14e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 103.55  E-value: 9.14e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2374 YQVMMLEHTPPGSAILSVSATDRDSGANGHISYHLASPAEG--FRVDPNNGTLFTTVgamALGHEGPGVVDVVLEARDHG 2451
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAK---PLDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 242397490 2452 APGRTAQATVHVQLKDQNDH 2471
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2275-2365 5.42e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.54  E-value: 5.42e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2275 ELRVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PH 2349
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGEngEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggpPL 82

                          90
                  ....*....|....*.
gi 242397490 2350 EGHANLTVLVEDVNDN 2365
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2705-2801 9.70e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.77  E-value: 9.70e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2705 STSLAENQPPGTLVTTLHAIDGDAGTFGRLRYSLLeavpGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAG 2784
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV----SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                          90
                  ....*....|....*..
gi 242397490 2785 NLSASVTVSVLITGEDE 2801
Cdd:cd11304    79 GPPLSSTATVTITVLDV 95
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 788-884 1.27e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.38  E-value: 1.27e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  788 QYVFSVPEDVAPGTSVGIIQAHNP-PGRLGPVTLTLSGGDPRGLFSLDSPSGLLKTLRPLDRELLgPVLELEVRA-GSGT 865
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQ-SSYTLTVTAtDGGG 79

                          90
                  ....*....|....*....
gi 242397490  866 PPVFAVARIRVLLDDVNDN 884
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2067-2160 9.53e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.07  E-value: 9.53e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2067 EAVLRENAPPGTPVISPKAV-HSGGSNGPITYSILSGNERGIFSIQPSTGAITVRSAegLDFETSPRLRLVLQAESGGAF 2145
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATdPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKP--LDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 242397490 2146 AFSV---LTLTLQDANDN 2160
Cdd:cd11304    81 PLSStatVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 683-775 1.14e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.14e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  683 EYAASLSAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGL 762
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|...
gi 242397490  763 QAEPIARVNISIV 775
Cdd:cd11304    81 PLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 144-245 1.23e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.23e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  144 LQIPEHTALGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYD 223
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTG-------EITTAKPLDREEQSSYTLTVTATD 76

                          90       100
                  ....*....|....*....|..
gi 242397490  224 GGSPPRRAQALLDVTLLDINDH 245
Cdd:cd11304    77 GGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 894-984 1.24e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.24e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  894 TVLLPQNTAPGTPIYTLRALDPDSGANSRITFNLLAGG-DGLFTVDPTTGHVRLMGPLGPPGGPAHELEVEARDGGSPPR 972
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|..
gi 242397490  973 TSHFRLRVVIQD 984
Cdd:cd11304    83 SSTATVTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2168-2266 2.62e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 90.84  E-value: 2.62e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2168 HYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGS 2247
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV-SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 242397490 2248 PALVGSATLTVMVIDTNDN 2266
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 998-1095 2.14e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 88.52  E-value: 2.14e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  998 TYRVDLPSGTTTGTQILQVQAQAPDG---SPVTYHLAADGASSPFGLESQSGWLWVRTALDRESQELYTLKVMAVSGSKa 1074
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSgenGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG- 79

                          90       100
                  ....*....|....*....|.
gi 242397490 1075 elGQQTGTATVRVIILNQNDH 1095
Cdd:cd11304    80 --PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2810-2916 3.79e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 73.50  E-value: 3.79e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2810 SFHFQVPEGAQRGHSLGHVQATDEDGGADGLVLYSLATSSP--YFGINQTTGALYLRV--DsrapgsgtttsggggrtrR 2885
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKplD------------------R 62

                          90       100       110
                  ....*....|....*....|....*....|.
gi 242397490 2886 EAPRELRLEVVARGPLPGSRSATVPVTVDIT 2916
Cdd:cd11304    63 EEQSSYTLTVTATDGGGPPLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1438-1535 4.43e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 73.12  E-value: 4.43e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1438 LPENPDPGATLYTFRASDADGpGPNSEVRYRLLRQEPPvPALRLDARTGALSAPRGLDRETTPALLLLVEATDRpanASR 1517
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDS-GENGEVTYSIVSGNED-GLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG---GGP 80

                          90
                  ....*....|....*...
gi 242397490 1518 RRAARVSARVFVTDENDN 1535
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 43-133 7.41e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 72.73  E-value: 7.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   43 LQIDEEQPAGTLIGDISA-GLPPGTAPPPMYFISAQEGSGVgtdLAIDEHSGVVRTARVLDRERRDRYRFTAVTPDG--- 118
Cdd:cd11304     4 VSVPENAPPGTVVLTVSAtDPDSGENGEVTYSIVSGNEDGL---FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggp 80

                          90
                  ....*....|....*...
gi 242397490  119 ---ATVEVTVRVADINDH 133
Cdd:cd11304    81 plsSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1329-1425 3.07e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 65.03  E-value: 3.07e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1329 VLTVTAAEGLRPGSLLGSVAPQEP--ASVGVLTYTLVGGaDPEGTFALDSASGRLYLARPLDFEAGPAWRaLTVRAEGPG 1406
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPdsGENGEVTYSIVSG-NEDGLFSIDPSTGEITTAKPLDREEQSSYT-LTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 242397490 1407 GAGAR-LLRVQVRVQDENEH 1425
Cdd:cd11304    79 GPPLSsTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1976-2052 1.25e-11

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 63.49  E-value: 1.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1976 LATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARspvalgPQDR------VLFIVATDLGRPARSATGVVV 2048
Cdd:cd11304    16 VLTVSATDPDSGENGEVTYSIVSGNEDGLfSIDPSTGEITTAK------PLDReeqssyTLTVTATDGGGPPLSSTATVT 89


                  ....
gi 242397490 2049 VGIQ 2052
Cdd:cd11304    90 ITVL 93
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1108-1201 3.00e-38

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 139.37  E-value: 3.00e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1108 VAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKaFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDGGSPPRSA 1187
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGL-FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSS 84

                          90
                  ....*....|....
gi 242397490 1188 TGTVHVAVLDLNDN 1201
Cdd:cd11304    85 TATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1646-1740 5.66e-36

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 132.82  E-value: 5.66e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1646 EYNVILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLP 1722
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYsivSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 242397490 1723 PLLTHITVRVTVEDENDH 1740
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 476-568 1.33e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 128.97  E-value: 1.33e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  476 LPEVALPGSFVVRVTARDPDQGTNGQITYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 555
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                          90
                  ....*....|...
gi 242397490  556 ATVSVALQDVNDN 568
Cdd:cd11304    86 ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 254-352 2.97e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 127.81  E-value: 2.97e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  254 YHAVVSESLAPGSPVLQVFASDADAGANGAVTYEInrRQSEGDGPFSIDAHTGFLRLERPLDFEQRRVHELVVQARDGGA 333
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 242397490  334 HPELGSAFVTVHVRDANDN 352
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2599-2695 2.64e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 122.42  E-value: 2.64e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2599 SYRVTVPEDMPVGAELLHVEASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLSRPLDCETQAQHQLVVQAADPAGT 2678
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 242397490 2679 HFS-LVPVTVEVQDVNDH 2695
Cdd:cd11304    81 PLSsTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1852-1949 2.77e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 122.42  E-value: 2.77e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1852 SYSVEVPEDAPVGTLLLQLQAHDPDDGDNGRVMYYLGAGTA-GAFLLEPTSGELSTATALDREHCASYAFSVTAVDGaAA 1930
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG-GG 79

                          90
                  ....*....|....*....
gi 242397490 1931 GPLSTTVPITITVRDVNDH 1949
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1544-1637 5.74e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 121.27  E-value: 5.74e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1544 RVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGG-DGHFRLHATTGALSVVRPLDREQRAEHVLTVVALDHGSPPR 1622
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*
gi 242397490 1623 SSTQLLTVSVVDVND 1637
Cdd:cd11304    83 SSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1750-1844 4.50e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.87  E-value: 4.50e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1750 SLEVPEGQDP-QTLTTLRASDPDGGLNGQLQYRILDGDSSGAFALDLTSGEFGTMRPLDREVEPAFQLQIEARDGGQPAL 1828
Cdd:cd11304     3 EVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*.
gi 242397490 1829 SATLLVTVTVLDANDH 1844
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 490-570 1.43e-29

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 113.98  E-value: 1.43e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    490 TARDPDQGTNGQITYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSSATVSVALQDVNDNE 569
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490    570 P 570
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2479-2591 3.53e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.56  E-value: 3.53e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2479 HYRVAVSEDLPPGSTLLTLEATDADgSRTHATVDYSIISGNRGRVFQLEPRLaevgdgvgpgpqalGCLVLLEPLDFESL 2558
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDGLFSIDPST--------------GEITTAKPLDREEQ 65

                          90       100       110
                  ....*....|....*....|....*....|...
gi 242397490 2559 TQYNLTVAAADRGQPPRSSAVPVTVTVLDVNDN 2591
Cdd:cd11304    66 SSYTLTVTATDGGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 577-675 3.85e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 110.48  E-value: 3.85e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  577 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGDVCTTRTLDRDQgPSSFDFTVTAIDG 656
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI---VSGNEDGLFSIDPSTGEITTAKPLDREE-QSSYTLTVTATDG 77

                          90       100
                  ....*....|....*....|.
gi 242397490  657 GG--LKSMVYVKVFVADENDN 675
Cdd:cd11304    78 GGppLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1123-1203 2.31e-27

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 107.44  E-value: 2.31e-27
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1123 ATDRDSGPNGRLTYSLQQLSEDSKaFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDGGSPPRSATGTVHVAVLDLNDNS 1202
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGL-FSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490   1203 P 1203
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 368-462 2.46e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 108.17  E-value: 2.46e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  368 RVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGG--EGHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPP 445
Cdd:cd11304     5 SVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGneDGLFSIDPSTGEIT---TAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*..
gi 242397490  446 LRAEAAFVLHVTDVNDN 462
Cdd:cd11304    82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1108-1196 4.68e-27

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 107.00  E-value: 4.68e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1108 VAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDsKAFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDGGSPPRSA 1187
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPG-GNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSS 83


                   ....*....
gi 242397490  1188 TGTVHVAVL 1196
Cdd:pfam00028   84 TATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1218-1306 3.74e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 104.70  E-value: 3.74e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1218 IQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT-GPGSELFSLHPHTGELHTAASLVRAERPHYVLTLSAHDQGSPPRS 1296
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|
gi 242397490 1297 ASLQLLVQVL 1306
Cdd:cd11304    84 STATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1766-1846 8.77e-26

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 103.20  E-value: 8.77e-26
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1766 RASDPDGGLNGQLQYRILDGDSSGAFALDLTSGEFGTMRPLDREVEPAFQLQIEARDGGQPALSATLLVTVTVLDANDHA 1845
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490   1846 P 1846
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2374-2471 9.14e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 103.55  E-value: 9.14e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2374 YQVMMLEHTPPGSAILSVSATDRDSGANGHISYHLASPAEG--FRVDPNNGTLFTTVgamALGHEGPGVVDVVLEARDHG 2451
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAK---PLDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 242397490 2452 APGRTAQATVHVQLKDQNDH 2471
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1545-1632 1.66e-25

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 102.76  E-value: 1.66e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1545 VRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGG-DGHFRLHATTGALSVVRPLDREQRAEHVLTVVALDHGSPPRS 1623
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82


                   ....*....
gi 242397490  1624 STQLLTVSV 1632
Cdd:pfam00028   83 STATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1665-1742 2.32e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 102.04  E-value: 2.32e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1665 KATDPDLGANGQVTY---GGVSGESFSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLPPLLTHITVRVTVEDENDHT 1741
Cdd:smart00112    1 SATDADSGENGKVTYsilSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490   1742 P 1742
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1561-1640 4.95e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 100.89  E-value: 4.95e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1561 VARDPDLGEAARVSYRLAAGGD-GHFRLHATTGALSVVRPLDREQRAEHVLTVVALDHGSPPRSSTQLLTVSVVDVNDEA 1639
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490   1640 P 1640
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
1647-1735 5.86e-25

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 101.22  E-value: 5.86e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1647 YNVILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLPP 1723
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYsilGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 242397490  1724 LLTHITVRVTVE 1735
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 273-354 2.09e-24

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 99.35  E-value: 2.09e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    273 ASDADAGANGAVTYEINrrQSEGDGPFSIDAHTGFLRLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDN 352
Cdd:smart00112    2 ATDADSGENGKVTYSIL--SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 242397490    353 QP 354
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2275-2365 5.42e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.54  E-value: 5.42e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2275 ELRVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PH 2349
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGEngEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggpPL 82

                          90
                  ....*....|....*.
gi 242397490 2350 EGHANLTVLVEDVNDN 2365
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
476-560 8.42e-24

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 97.76  E-value: 8.42e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   476 LPEVALPGSFVVRVTARDPDQGTNGQITYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 555
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*
gi 242397490   556 ATVSV 560
Cdd:pfam00028   85 ATVTI 89
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2705-2801 9.70e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.77  E-value: 9.70e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2705 STSLAENQPPGTLVTTLHAIDGDAGTFGRLRYSLLeavpGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAG 2784
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV----SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                          90
                  ....*....|....*..
gi 242397490 2785 NLSASVTVSVLITGEDE 2801
Cdd:cd11304    79 GPPLSSTATVTITVLDV 95
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 788-884 1.27e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.38  E-value: 1.27e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  788 QYVFSVPEDVAPGTSVGIIQAHNP-PGRLGPVTLTLSGGDPRGLFSLDSPSGLLKTLRPLDRELLgPVLELEVRA-GSGT 865
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQ-SSYTLTVTAtDGGG 79

                          90
                  ....*....|....*....
gi 242397490  866 PPVFAVARIRVLLDDVNDN 884
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1853-1943 7.88e-23

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 95.06  E-value: 7.88e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1853 YSVEVPEDAPVGTLLLQLQAHDPDDGDNGRVMYY-LGAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDgAAAG 1931
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSiLGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATD-SGGP 79

                           90
                   ....*....|..
gi 242397490  1932 PLSTTVPITITV 1943
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2067-2160 9.53e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.07  E-value: 9.53e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2067 EAVLRENAPPGTPVISPKAV-HSGGSNGPITYSILSGNERGIFSIQPSTGAITVRSAegLDFETSPRLRLVLQAESGGAF 2145
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATdPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKP--LDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 242397490 2146 AFSV---LTLTLQDANDN 2160
Cdd:cd11304    81 PLSStatVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 683-775 1.14e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.14e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  683 EYAASLSAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGL 762
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|...
gi 242397490  763 QAEPIARVNISIV 775
Cdd:cd11304    81 PLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 144-245 1.23e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.23e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  144 LQIPEHTALGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYD 223
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTG-------EITTAKPLDREEQSSYTLTVTATD 76

                          90       100
                  ....*....|....*....|..
gi 242397490  224 GGSPPRRAQALLDVTLLDINDH 245
Cdd:cd11304    77 GGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 894-984 1.24e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.24e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  894 TVLLPQNTAPGTPIYTLRALDPDSGANSRITFNLLAGG-DGLFTVDPTTGHVRLMGPLGPPGGPAHELEVEARDGGSPPR 972
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|..
gi 242397490  973 TSHFRLRVVIQD 984
Cdd:cd11304    83 SSTATVTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2168-2266 2.62e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 90.84  E-value: 2.62e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2168 HYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGS 2247
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV-SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 242397490 2248 PALVGSATLTVMVIDTNDN 2266
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2619-2697 5.01e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 89.72  E-value: 5.01e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2619 ASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLSRPLDCETQAQHQLVVQAADPAG-THFSLVPVTVEVQDVNDHGP 2697
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGpPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1871-1951 9.72e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 88.56  E-value: 9.72e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1871 QAHDPDDGDNGRVMYYL-GAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDGaAAGPLSTTVPITITVRDVNDH 1949
Cdd:smart00112    1 SATDADSGENGKVTYSIlSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG-GGPPLSSTATVTITVLDVNDN 79


                    ..
gi 242397490   1950 AP 1951
Cdd:smart00112   80 AP 81
Cadherin pfam00028
Cadherin domain;
1217-1306 1.52e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 88.51  E-value: 1.52e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1217 PIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSE-LFSLHPHTGELHTAASLVRAERPHYVLTLSAHDQGSPPR 1295
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|.
gi 242397490  1296 SASLQLLVQVL 1306
Cdd:pfam00028   82 SSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2499-2593 1.55e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 88.18  E-value: 1.55e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2499 ATDADgSRTHATVDYSIISGNRGRVFQLEPRLaevgdgvgpgpqalGCLVLLEPLDFESLTQYNLTVAAADRGQPPRSSA 2578
Cdd:smart00112    2 ATDAD-SGENGKVTYSILSGNDDGLFSIDPET--------------GEITTTKPLDREEQPEYTLTVEATDGGGPPLSST 66

                            90
                    ....*....|....*
gi 242397490   2579 VPVTVTVLDVNDNPP 2593
Cdd:smart00112   67 ATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
254-346 1.63e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 88.51  E-value: 1.63e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   254 YHAVVSESLAPGSPVLQVFASDADAGANGAVTYEInrRQSEGDGPFSIDAHTGFLRLERPLDFEQRRVHELVVQARDGGA 333
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSI--LGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|...
gi 242397490   334 HPELGSAFVTVHV 346
Cdd:pfam00028   79 PPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 383-464 2.04e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 87.79  E-value: 2.04e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    383 SVSDPDDGDFAHVNVSLEGGE--GHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPPLRAEAAFVLHVTDVN 460
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNddGLFSIDPETGEIT---TTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 242397490    461 DNAP 464
Cdd:smart00112   78 DNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 998-1095 2.14e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 88.52  E-value: 2.14e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  998 TYRVDLPSGTTTGTQILQVQAQAPDG---SPVTYHLAADGASSPFGLESQSGWLWVRTALDRESQELYTLKVMAVSGSKa 1074
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSgenGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG- 79

                          90       100
                  ....*....|....*....|.
gi 242397490 1075 elGQQTGTATVRVIILNQNDH 1095
Cdd:cd11304    80 --PPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1752-1839 2.75e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 87.74  E-value: 2.75e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1752 EVPEGQDPQT-LTTLRASDPDGGLNGQLQYRILDGDSSGAFALDLTSGEFGTMRPLDREVEPAFQLQIEARDGGQPALSA 1830
Cdd:pfam00028    4 SVPENAPVGTeVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSS 83


                   ....*....
gi 242397490  1831 TLLVTVTVL 1839
Cdd:pfam00028   84 TATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 595-677 4.57e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.63  E-value: 4.57e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    595 TATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGDVCTTRTLDRDQGPsSFDFTVTAIDGGG--LKSMVYVKVFVADE 672
Cdd:smart00112    1 SATDADSGENGKVTYSI---LSGNDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGppLSSTATVTITVLDV 76


                    ....*
gi 242397490    673 NDNPP 677
Cdd:smart00112   77 NDNAP 81
Cadherin pfam00028
Cadherin domain;
2480-2586 2.59e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 82.35  E-value: 2.59e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2480 YRVAVSEDLPPGSTLLTLEATDADGSrTHATVDYSIISGNRGRVFQLEPRlaevgDGVgpgpqalgcLVLLEPLDFESLT 2559
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLG-PNGRIFYSILGGGPGGNFRIDPD-----TGD---------ISTTKPLDRESIG 65

                           90       100
                   ....*....|....*....|....*..
gi 242397490  2560 QYNLTVAAADRGQPPRSSAVPVTVTVL 2586
Cdd:pfam00028   66 EYELTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2600-2690 2.88e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 81.96  E-value: 2.88e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2600 YRVTVPEDMPVGAELLHVEASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLSRPLDCETQAQHQLVVQAADPAGTH 2679
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 242397490  2680 -FSLVPVTVEVQ 2690
Cdd:pfam00028   81 lSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2392-2473 8.28e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 80.47  E-value: 8.28e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2392 SATDRDSGANGHISYHLASPAEG--FRVDPNNGTLFTTVgamALGHEGPGVVDVVLEARDHGAPGRTAQATVHVQLKDQN 2469
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDglFSIDPETGEITTTK---PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 242397490   2470 DHAP 2473
Cdd:smart00112   78 DNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 161-247 1.57e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 79.70  E-value: 1.57e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    161 ARDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLL 240
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETG-------EITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74


                    ....*..
gi 242397490    241 DINDHAP 247
Cdd:smart00112   75 DVNDNAP 81
Cadherin pfam00028
Cadherin domain;
684-774 1.04e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 77.73  E-value: 1.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   684 YAASLSAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGLQ 763
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|.
gi 242397490   764 AEPIARVNISI 774
Cdd:pfam00028   81 LSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2188-2268 1.51e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 76.62  E-value: 1.51e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2188 ADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNR 2267
Cdd:smart00112    2 ATDADSGENGKVTYSIL-SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490   2268 P 2268
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
2705-2797 1.62e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 76.96  E-value: 1.62e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2705 STSLAENQPPGTLVTTLHAIDGDAGTFGRLRYSLLEavpGPEGReAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAG 2784
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILG---GGPGG-NFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 242397490  2785 --NLSASVTVSVLIT 2797
Cdd:pfam00028   78 gpPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
368-457 7.11e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 75.41  E-value: 7.11e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   368 RVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGE--GHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPP 445
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpgGNFRIDPDTGDIS---TTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 242397490   446 LRAEAAFVLHVT 457
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1234-1306 8.06e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 74.69  E-value: 8.06e-16
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 242397490   1234 QAKDPDEGENGTILYTLT-GPGSELFSLHPHTGELHTAASLVRAERPHYVLTLSAHDQGSPPRSASLQLLVQVL 1306
Cdd:smart00112    1 SATDADSGENGKVTYSILsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2090-2162 9.70e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 74.31  E-value: 9.70e-16
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 242397490   2090 GSNGPITYSILSGNERGIFSIQPSTGAITVRSAegLDFETSPRLRLVLQAESGGAFAFSV---LTLTLQDANDNAP 2162
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKP--LDREEQPEYTLTVEATDGGGPPLSStatVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2295-2367 1.55e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.92  E-value: 1.55e-15
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 242397490   2295 DVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PHEGHANLTVLVEDVNDNVP 2367
Cdd:smart00112    4 DADSGEngKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGggpPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
897-983 2.86e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 73.49  E-value: 2.86e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   897 LPQNTAPGTPIYTLRALDPDSGANSRITFNLLAGG-DGLFTVDPTTGHVRLMGPLGPPGGPAHELEVEARDGGSPPRTSH 975
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*...
gi 242397490   976 FRLRVVIQ 983
Cdd:pfam00028   85 ATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2810-2916 3.79e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 73.50  E-value: 3.79e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2810 SFHFQVPEGAQRGHSLGHVQATDEDGGADGLVLYSLATSSP--YFGINQTTGALYLRV--DsrapgsgtttsggggrtrR 2885
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKplD------------------R 62

                          90       100       110
                  ....*....|....*....|....*....|.
gi 242397490 2886 EAPRELRLEVVARGPLPGSRSATVPVTVDIT 2916
Cdd:cd11304    63 EEQSSYTLTVTATDGGGPPLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1438-1535 4.43e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 73.12  E-value: 4.43e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1438 LPENPDPGATLYTFRASDADGpGPNSEVRYRLLRQEPPvPALRLDARTGALSAPRGLDRETTPALLLLVEATDRpanASR 1517
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDS-GENGEVTYSIVSGNED-GLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG---GGP 80

                          90
                  ....*....|....*...
gi 242397490 1518 RRAARVSARVFVTDENDN 1535
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 43-133 7.41e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 72.73  E-value: 7.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   43 LQIDEEQPAGTLIGDISA-GLPPGTAPPPMYFISAQEGSGVgtdLAIDEHSGVVRTARVLDRERRDRYRFTAVTPDG--- 118
Cdd:cd11304     4 VSVPENAPPGTVVLTVSAtDPDSGENGEVTYSIVSGNEDGL---FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggp 80

                          90
                  ....*....|....*...
gi 242397490  119 ---ATVEVTVRVADINDH 133
Cdd:cd11304    81 plsSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
2374-2465 9.12e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 71.95  E-value: 9.12e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2374 YQVMMLEHTPPGSAILSVSATDRDSGANGHISYHLASPAEG--FRVDPNNGTLFTTvgaMALGHEGPGVVDVVLEARDHG 2451
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTT---KPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....
gi 242397490  2452 APGRTAQATVHVQL 2465
Cdd:pfam00028   78 GPPLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
577-658 3.74e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.41  E-value: 3.74e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   577 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGDVCTTRTLDRDQgPSSFDFTVTAIDG 656
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSI---LGGGPGGNFRIDPDTGDISTTKPLDRES-IGEYELTVEATDS 76


                   ..
gi 242397490   657 GG 658
Cdd:pfam00028   77 GG 78
Cadherin pfam00028
Cadherin domain;
2169-2261 1.69e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.48  E-value: 1.69e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2169 YVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGSP 2248
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIL-GGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 242397490  2249 ALVGSATLTVMVI 2261
Cdd:pfam00028   80 PLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2067-2155 1.98e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.48  E-value: 1.98e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2067 EAVLRENAPPGTPVISPKAVHS-GGSNGPITYSILSGNERGIFSIQPSTGAITVRSAegLDFETSPRLRLVLQAESGGAF 2145
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKP--LDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|.
gi 242397490  2146 A-FSVLTLTLQ 2155
Cdd:pfam00028   80 PlSSTATVTIT 90
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1020-1097 4.01e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 4.01e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 242397490   1020 APDGSPVTYHLAADGASSPFGLESQSGWLWVRTALDRESQELYTLKVMAVSGSKAELgqqTGTATVRVIILNQNDHSP 1097
Cdd:smart00112    7 SGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPL---SSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2722-2801 4.34e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 4.34e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2722 HAIDGDAGTFGRLRYSLLeavpGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAGNLSASVTVSVLITGEDE 2801
Cdd:smart00112    1 SATDADSGENGKVTYSIL----SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDV 76
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 813-886 4.55e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 4.55e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 242397490    813 GRLGPVTLTLSGGDPRGLFSLDSPSGLLKTLRPLDRElLGPVLELEVRA-GSGTPPVFAVARIRVLLDDVNDNSP 886
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDRE-EQPEYTLTVEAtDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
999-1090 6.63e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 66.94  E-value: 6.63e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   999 YRVDLPSGTTTGTQILQVQAQAPDGSP---VTYHLAADGASSPFGLESQSGWLWVRTALDRESQELYTLKVMAVSGSKae 1075
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngrIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG-- 78

                           90
                   ....*....|....*
gi 242397490  1076 lGQQTGTATVRVIIL 1090
Cdd:pfam00028   79 -PPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 702-775 1.53e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.45  E-value: 1.53e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 242397490    702 HAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGLQAEPIARVNISIV 775
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
Cadherin pfam00028
Cadherin domain;
2277-2360 2.33e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.40  E-value: 2.33e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2277 RVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PHEG 2351
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPngRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSggpPLSS 83


                   ....*....
gi 242397490  2352 HANLTVLVE 2360
Cdd:pfam00028   84 TATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1329-1425 3.07e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 65.03  E-value: 3.07e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1329 VLTVTAAEGLRPGSLLGSVAPQEP--ASVGVLTYTLVGGaDPEGTFALDSASGRLYLARPLDFEAGPAWRaLTVRAEGPG 1406
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPdsGENGEVTYSIVSG-NEDGLFSIDPSTGEITTAKPLDREEQSSYT-LTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 242397490 1407 GAGAR-LLRVQVRVQDENEH 1425
Cdd:cd11304    79 GPPLSsTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 911-984 4.55e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 63.91  E-value: 4.55e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 242397490    911 RALDPDSGANSRITFNLLAGGD-GLFTVDPTTGHVRLMGPLGPPGGPAHELEVEARDGGSPPRTSHFRLRVVIQD 984
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLD 75
Cadherin pfam00028
Cadherin domain;
145-240 9.11e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 63.47  E-value: 9.11e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   145 QIPEHTALGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYDG 224
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTG-------DISTTKPLDRESIGEYELTVEATDS 76

                           90
                   ....*....|....*.
gi 242397490   225 GSPPRRAQALLDVTLL 240
Cdd:pfam00028   77 GGPPLSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1976-2052 1.25e-11

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 63.49  E-value: 1.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1976 LATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARspvalgPQDR------VLFIVATDLGRPARSATGVVV 2048
Cdd:cd11304    16 VLTVSATDPDSGENGEVTYSIVSGNEDGLfSIDPSTGEITTAK------PLDReeqssyTLTVTATDGGGPPLSSTATVT 89


                  ....
gi 242397490 2049 VGIQ 2052
Cdd:cd11304    90 ITVL 93
Cadherin pfam00028
Cadherin domain;
789-878 1.27e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 63.09  E-value: 1.27e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   789 YVFSVPEDVAPGTSVGIIQAHNP-PGRLGPVTLTLSGGDPRGLFSLDSPSGLLKTLRPLDRELLGPVlELEVRA-GSGTP 866
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEY-ELTVEAtDSGGP 79

                           90
                   ....*....|..
gi 242397490   867 PVFAVARIRVLL 878
Cdd:pfam00028   80 PLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 72-135 1.32e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 62.75  E-value: 1.32e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490     72 YFISAQEGSGVgtdLAIDEHSGVVRTARVLDRERRDRYRFTAV------TPDGATVEVTVRVADINDHAP 135
Cdd:smart00112   15 YSILSGNDDGL---FSIDPETGEITTTKPLDREEQPEYTLTVEatdgggPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1452-1537 3.57e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 61.60  E-value: 3.57e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1452 RASDADGpGPNSEVRYRLLRQEPPVPaLRLDARTGALSAPRGLDRETTPALLLLVEATDRpanASRRRAARVSARVFVTD 1531
Cdd:smart00112    1 SATDADS-GENGKVTYSILSGNDDGL-FSIDPETGEITTTKPLDREEQPEYTLTVEATDG---GGPPLSSTATVTITVLD 75


                    ....*.
gi 242397490   1532 ENDNAP 1537
Cdd:smart00112   76 VNDNAP 81
Cadherin pfam00028
Cadherin domain;
1976-2049 3.26e-10

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 59.24  E-value: 3.26e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1976 LATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARspvalgPQDR------VLFIVATDLGRPARSATGVVV 2048
Cdd:pfam00028   15 VLTVTATDPDLGPNGRIFYSILGGGPGGNfRIDPDTGDISTTK------PLDResigeyELTVEATDSGGPPLSSTATVT 88


                   .
gi 242397490  2049 V 2049
Cdd:pfam00028   89 I 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1356-1427 1.21e-09

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 57.36  E-value: 1.21e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 242397490   1356 GVLTYTLVGGaDPEGTFALDSASGRLYLARPLDFEAGPAWRaLTVRAEGPGGAGAR-LLRVQVRVQDENEHAP 1427
Cdd:smart00112   11 GKVTYSILSG-NDDGLFSIDPETGEITTTKPLDREEQPEYT-LTVEATDGGGPPLSsTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
2811-2916 2.87e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 56.54  E-value: 2.87e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2811 FHFQVPEGAQRGHSLGHVQATDEDGGADGLVLYSLATSSPY--FGINQTTGALYL--RVDsrapgsgtttsggggrtrRE 2886
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTtkPLD------------------RE 62

                           90       100       110
                   ....*....|....*....|....*....|
gi 242397490  2887 APRELRLEVVARGPLPGSRSATVPVTVDIT 2916
Cdd:pfam00028   63 SIGEYELTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
44-127 1.45e-07

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 51.53  E-value: 1.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    44 QIDEEQPAGTLIGDISAG---LPPGTAPppMYFISAQEGSGVgtdLAIDEHSGVVRTARVLDRERRDRYRFTAV------ 114
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATdpdLGPNGRI--FYSILGGGPGGN---FRIDPDTGDISTTKPLDRESIGEYELTVEatdsgg 78

                           90
                   ....*....|...
gi 242397490   115 TPDGATVEVTVRV 127
Cdd:pfam00028   79 PPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1980-2052 2.32e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 50.81  E-value: 2.32e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1980 RAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARSPvalgpqDR------VLFIVATDLGRPARSATGVVVVGIQ 2052
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLfSIDPETGEITTTKPL------DReeqpeyTLTVEATDGGGPPLSSTATVTITVL 74
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
 1224-1794 3.24e-06

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 53.34  E-value: 3.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1224 VPPGTLVTTLQAKDPDEGENGTILYTLTGPGSELFSLHPHTGELHTA------ASLVRAERPHYV----------LTLSA 1287
Cdd:COG3321   797 VGPGPVLTGLVRQCLAAAGDAVVLPSLRRGEDELAQLLTALAQLWVAgvpvdwSALYPGRGRRRVplptypfqreDAAAA 876

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1288 HDQGSPPRSASLQLLVQVLPSTRVVESPDLIEADSAATVPVVLTVTAAEGLRPGSLLGSVAPQEPASVGVLTYTLVGGAD 1367
Cdd:COG3321   877 LLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALLALAAAAAAAAAAL 956

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1368 PEGTFALDSASGRLYLARPLDFEAGPAWRALTVRAEGPGGAGARLLRVQVRVQDENEHAPTFARDPLALALPENPDPGAT 1447
Cdd:COG3321   957 AAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLALAALLAAAAAALA 1036

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1448 LYTFRASDADGPGPNSEVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAARVSARV 1527
Cdd:COG3321  1037 AAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAALAAALLLLALLAALA 1116

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1528 FVTDENDNAPVFASPSRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGGDGHFRLHATTGALSVVRPLDREQRAE 1607
Cdd:COG3321  1117 LAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALALAAALAAALAGLAALL 1196

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1608 HVLTVVALDHGSPPRSSTQLLTVSVVDVNDEAPAFPQQEYNVILRENSPPGTSLL---TLKATDPDLGANGQVTYGGVSG 1684
Cdd:COG3321  1197 LAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAaaaLLAALAALALLAAAAGLAALAA 1276

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1685 ESFSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLPPLLTHITVRVTVEDENDHTPTFGNTHLSLEVPEGQDPQTLTT 1764
Cdd:COG3321  1277 AAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALAALAAAVAAALALAAAAAAAAAAAAA 1356

                         570       580       590
                  ....*....|....*....|....*....|
gi 242397490 1765 LRASDPDGGLNGQLQYRILDGDSSGAFALD 1794
Cdd:COG3321  1357 AAAAAALAAAAGAAAAAAALALAALAAAVA 1386
Cadherin pfam00028
Cadherin domain;
1331-1417 1.57e-05

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 45.75  E-value: 1.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1331 TVTAAEGLRPGSLLGSVA---PQEPASvGVLTYTLVGGaDPEGTFALDSASGRLYLARPLDFEAgPAWRALTVRAEGPGG 1407
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTatdPDLGPN-GRIFYSILGG-GPGGNFRIDPDTGDISTTKPLDRES-IGEYELTVEATDSGG 78

                           90
                   ....*....|...
gi 242397490  1408 AGAR---LLRVQV 1417
Cdd:pfam00028   79 PPLSstaTVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2829-2916 4.61e-04

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 41.18  E-value: 4.61e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2829 QATDEDGGADGLVLYSLATSSP--YFGINQTTGALYL--RVDsrapgsgtttsggggrtrREAPRELRLEVVARGPLPGS 2904
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdgLFSIDPETGEITTtkPLD------------------REEQPEYTLTVEATDGGGPP 62

                            90
                    ....*....|..
gi 242397490   2905 RSATVPVTVDIT 2916
Cdd:smart00112   63 LSSTATVTITVL 74
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 1729-1951 2.52e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 43.88  E-value: 2.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1729 TVRVTVEDENdHTPTfGNTHLSLEVPEGqDPQTLTTlRASDPDGGLngqLQYRILDgDSSGAFALDLTSGEFGTMRPLDR 1808
Cdd:NF038112 1271 TVTVLVRNVN-RAPV-AVAGAPATVDER-STVTLDG-SGTDADGDA---LTYAWTQ-TSGPAVTLTGATTATATFTAPEV 1342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1809 EVEPAFQLQIEARDGGQpalSATLLVTVTVLDANdHAPVFPVPSySVEVPEDAPVgtlLLQLQAHDPDdgdnGRVMYYLG 1888
Cdd:NF038112 1343 TADTQLTFTLTVSDGTA---SATDTVTVTVRNVN-RAPVANAGA-DQTVDERSTV---TLSGSATDPD----GDALTYAW 1410

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 242397490 1889 AGTAG-AFLLEPTSGELSTATALDREHCASYAFSVTAvdgAAAGPLSTTVPITITVRDVNdHAP 1951
Cdd:NF038112 1411 TQTAGpTVTLTGADTATASFTAPEVAADTELTFQLTV---SADGQASADVTVTVTVRNVN-RAP 1470
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1108-1201 3.00e-38

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 139.37  E-value: 3.00e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1108 VAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKaFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDGGSPPRSA 1187
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGL-FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSS 84

                          90
                  ....*....|....
gi 242397490 1188 TGTVHVAVLDLNDN 1201
Cdd:cd11304    85 TATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1646-1740 5.66e-36

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 132.82  E-value: 5.66e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1646 EYNVILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLP 1722
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYsivSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 242397490 1723 PLLTHITVRVTVEDENDH 1740
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 476-568 1.33e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 128.97  E-value: 1.33e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  476 LPEVALPGSFVVRVTARDPDQGTNGQITYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 555
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                          90
                  ....*....|...
gi 242397490  556 ATVSVALQDVNDN 568
Cdd:cd11304    86 ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 254-352 2.97e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 127.81  E-value: 2.97e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  254 YHAVVSESLAPGSPVLQVFASDADAGANGAVTYEInrRQSEGDGPFSIDAHTGFLRLERPLDFEQRRVHELVVQARDGGA 333
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 242397490  334 HPELGSAFVTVHVRDANDN 352
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2599-2695 2.64e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 122.42  E-value: 2.64e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2599 SYRVTVPEDMPVGAELLHVEASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLSRPLDCETQAQHQLVVQAADPAGT 2678
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 242397490 2679 HFS-LVPVTVEVQDVNDH 2695
Cdd:cd11304    81 PLSsTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1852-1949 2.77e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 122.42  E-value: 2.77e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1852 SYSVEVPEDAPVGTLLLQLQAHDPDDGDNGRVMYYLGAGTA-GAFLLEPTSGELSTATALDREHCASYAFSVTAVDGaAA 1930
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG-GG 79

                          90
                  ....*....|....*....
gi 242397490 1931 GPLSTTVPITITVRDVNDH 1949
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1544-1637 5.74e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 121.27  E-value: 5.74e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1544 RVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGG-DGHFRLHATTGALSVVRPLDREQRAEHVLTVVALDHGSPPR 1622
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*
gi 242397490 1623 SSTQLLTVSVVDVND 1637
Cdd:cd11304    83 SSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1750-1844 4.50e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.87  E-value: 4.50e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1750 SLEVPEGQDP-QTLTTLRASDPDGGLNGQLQYRILDGDSSGAFALDLTSGEFGTMRPLDREVEPAFQLQIEARDGGQPAL 1828
Cdd:cd11304     3 EVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*.
gi 242397490 1829 SATLLVTVTVLDANDH 1844
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 490-570 1.43e-29

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 113.98  E-value: 1.43e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    490 TARDPDQGTNGQITYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSSATVSVALQDVNDNE 569
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490    570 P 570
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2479-2591 3.53e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.56  E-value: 3.53e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2479 HYRVAVSEDLPPGSTLLTLEATDADgSRTHATVDYSIISGNRGRVFQLEPRLaevgdgvgpgpqalGCLVLLEPLDFESL 2558
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDGLFSIDPST--------------GEITTAKPLDREEQ 65

                          90       100       110
                  ....*....|....*....|....*....|...
gi 242397490 2559 TQYNLTVAAADRGQPPRSSAVPVTVTVLDVNDN 2591
Cdd:cd11304    66 SSYTLTVTATDGGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 577-675 3.85e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 110.48  E-value: 3.85e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  577 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGDVCTTRTLDRDQgPSSFDFTVTAIDG 656
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI---VSGNEDGLFSIDPSTGEITTAKPLDREE-QSSYTLTVTATDG 77

                          90       100
                  ....*....|....*....|.
gi 242397490  657 GG--LKSMVYVKVFVADENDN 675
Cdd:cd11304    78 GGppLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1123-1203 2.31e-27

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 107.44  E-value: 2.31e-27
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1123 ATDRDSGPNGRLTYSLQQLSEDSKaFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDGGSPPRSATGTVHVAVLDLNDNS 1202
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGL-FSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490   1203 P 1203
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 368-462 2.46e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 108.17  E-value: 2.46e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  368 RVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGG--EGHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPP 445
Cdd:cd11304     5 SVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGneDGLFSIDPSTGEIT---TAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*..
gi 242397490  446 LRAEAAFVLHVTDVNDN 462
Cdd:cd11304    82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1108-1196 4.68e-27

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 107.00  E-value: 4.68e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1108 VAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDsKAFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDGGSPPRSA 1187
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPG-GNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSS 83


                   ....*....
gi 242397490  1188 TGTVHVAVL 1196
Cdd:pfam00028   84 TATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1218-1306 3.74e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 104.70  E-value: 3.74e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1218 IQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT-GPGSELFSLHPHTGELHTAASLVRAERPHYVLTLSAHDQGSPPRS 1296
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|
gi 242397490 1297 ASLQLLVQVL 1306
Cdd:cd11304    84 STATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1766-1846 8.77e-26

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 103.20  E-value: 8.77e-26
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1766 RASDPDGGLNGQLQYRILDGDSSGAFALDLTSGEFGTMRPLDREVEPAFQLQIEARDGGQPALSATLLVTVTVLDANDHA 1845
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490   1846 P 1846
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2374-2471 9.14e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 103.55  E-value: 9.14e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2374 YQVMMLEHTPPGSAILSVSATDRDSGANGHISYHLASPAEG--FRVDPNNGTLFTTVgamALGHEGPGVVDVVLEARDHG 2451
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAK---PLDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 242397490 2452 APGRTAQATVHVQLKDQNDH 2471
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1545-1632 1.66e-25

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 102.76  E-value: 1.66e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1545 VRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGG-DGHFRLHATTGALSVVRPLDREQRAEHVLTVVALDHGSPPRS 1623
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82


                   ....*....
gi 242397490  1624 STQLLTVSV 1632
Cdd:pfam00028   83 STATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1665-1742 2.32e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 102.04  E-value: 2.32e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1665 KATDPDLGANGQVTY---GGVSGESFSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLPPLLTHITVRVTVEDENDHT 1741
Cdd:smart00112    1 SATDADSGENGKVTYsilSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490   1742 P 1742
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1561-1640 4.95e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 100.89  E-value: 4.95e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1561 VARDPDLGEAARVSYRLAAGGD-GHFRLHATTGALSVVRPLDREQRAEHVLTVVALDHGSPPRSSTQLLTVSVVDVNDEA 1639
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490   1640 P 1640
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
1647-1735 5.86e-25

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 101.22  E-value: 5.86e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1647 YNVILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLPP 1723
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYsilGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 242397490  1724 LLTHITVRVTVE 1735
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 273-354 2.09e-24

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 99.35  E-value: 2.09e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    273 ASDADAGANGAVTYEINrrQSEGDGPFSIDAHTGFLRLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDN 352
Cdd:smart00112    2 ATDADSGENGKVTYSIL--SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 242397490    353 QP 354
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2275-2365 5.42e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.54  E-value: 5.42e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2275 ELRVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PH 2349
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGEngEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggpPL 82

                          90
                  ....*....|....*.
gi 242397490 2350 EGHANLTVLVEDVNDN 2365
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
476-560 8.42e-24

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 97.76  E-value: 8.42e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   476 LPEVALPGSFVVRVTARDPDQGTNGQITYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 555
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*
gi 242397490   556 ATVSV 560
Cdd:pfam00028   85 ATVTI 89
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2705-2801 9.70e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.77  E-value: 9.70e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2705 STSLAENQPPGTLVTTLHAIDGDAGTFGRLRYSLLeavpGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAG 2784
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV----SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                          90
                  ....*....|....*..
gi 242397490 2785 NLSASVTVSVLITGEDE 2801
Cdd:cd11304    79 GPPLSSTATVTITVLDV 95
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 788-884 1.27e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.38  E-value: 1.27e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  788 QYVFSVPEDVAPGTSVGIIQAHNP-PGRLGPVTLTLSGGDPRGLFSLDSPSGLLKTLRPLDRELLgPVLELEVRA-GSGT 865
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQ-SSYTLTVTAtDGGG 79

                          90
                  ....*....|....*....
gi 242397490  866 PPVFAVARIRVLLDDVNDN 884
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1853-1943 7.88e-23

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 95.06  E-value: 7.88e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1853 YSVEVPEDAPVGTLLLQLQAHDPDDGDNGRVMYY-LGAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDgAAAG 1931
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSiLGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATD-SGGP 79

                           90
                   ....*....|..
gi 242397490  1932 PLSTTVPITITV 1943
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2067-2160 9.53e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.07  E-value: 9.53e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2067 EAVLRENAPPGTPVISPKAV-HSGGSNGPITYSILSGNERGIFSIQPSTGAITVRSAegLDFETSPRLRLVLQAESGGAF 2145
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATdPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKP--LDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 242397490 2146 AFSV---LTLTLQDANDN 2160
Cdd:cd11304    81 PLSStatVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 683-775 1.14e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.14e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  683 EYAASLSAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGL 762
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|...
gi 242397490  763 QAEPIARVNISIV 775
Cdd:cd11304    81 PLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 144-245 1.23e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.23e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  144 LQIPEHTALGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYD 223
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTG-------EITTAKPLDREEQSSYTLTVTATD 76

                          90       100
                  ....*....|....*....|..
gi 242397490  224 GGSPPRRAQALLDVTLLDINDH 245
Cdd:cd11304    77 GGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 894-984 1.24e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.24e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  894 TVLLPQNTAPGTPIYTLRALDPDSGANSRITFNLLAGG-DGLFTVDPTTGHVRLMGPLGPPGGPAHELEVEARDGGSPPR 972
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|..
gi 242397490  973 TSHFRLRVVIQD 984
Cdd:cd11304    83 SSTATVTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2168-2266 2.62e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 90.84  E-value: 2.62e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2168 HYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGS 2247
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV-SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 242397490 2248 PALVGSATLTVMVIDTNDN 2266
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2619-2697 5.01e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 89.72  E-value: 5.01e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2619 ASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLSRPLDCETQAQHQLVVQAADPAG-THFSLVPVTVEVQDVNDHGP 2697
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGpPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1871-1951 9.72e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 88.56  E-value: 9.72e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1871 QAHDPDDGDNGRVMYYL-GAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDGaAAGPLSTTVPITITVRDVNDH 1949
Cdd:smart00112    1 SATDADSGENGKVTYSIlSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG-GGPPLSSTATVTITVLDVNDN 79


                    ..
gi 242397490   1950 AP 1951
Cdd:smart00112   80 AP 81
Cadherin pfam00028
Cadherin domain;
1217-1306 1.52e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 88.51  E-value: 1.52e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1217 PIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSE-LFSLHPHTGELHTAASLVRAERPHYVLTLSAHDQGSPPR 1295
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|.
gi 242397490  1296 SASLQLLVQVL 1306
Cdd:pfam00028   82 SSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2499-2593 1.55e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 88.18  E-value: 1.55e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2499 ATDADgSRTHATVDYSIISGNRGRVFQLEPRLaevgdgvgpgpqalGCLVLLEPLDFESLTQYNLTVAAADRGQPPRSSA 2578
Cdd:smart00112    2 ATDAD-SGENGKVTYSILSGNDDGLFSIDPET--------------GEITTTKPLDREEQPEYTLTVEATDGGGPPLSST 66

                            90
                    ....*....|....*
gi 242397490   2579 VPVTVTVLDVNDNPP 2593
Cdd:smart00112   67 ATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
254-346 1.63e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 88.51  E-value: 1.63e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   254 YHAVVSESLAPGSPVLQVFASDADAGANGAVTYEInrRQSEGDGPFSIDAHTGFLRLERPLDFEQRRVHELVVQARDGGA 333
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSI--LGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|...
gi 242397490   334 HPELGSAFVTVHV 346
Cdd:pfam00028   79 PPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 383-464 2.04e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 87.79  E-value: 2.04e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    383 SVSDPDDGDFAHVNVSLEGGE--GHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPPLRAEAAFVLHVTDVN 460
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNddGLFSIDPETGEIT---TTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 242397490    461 DNAP 464
Cdd:smart00112   78 DNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 998-1095 2.14e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 88.52  E-value: 2.14e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  998 TYRVDLPSGTTTGTQILQVQAQAPDG---SPVTYHLAADGASSPFGLESQSGWLWVRTALDRESQELYTLKVMAVSGSKa 1074
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSgenGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG- 79

                          90       100
                  ....*....|....*....|.
gi 242397490 1075 elGQQTGTATVRVIILNQNDH 1095
Cdd:cd11304    80 --PPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1752-1839 2.75e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 87.74  E-value: 2.75e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1752 EVPEGQDPQT-LTTLRASDPDGGLNGQLQYRILDGDSSGAFALDLTSGEFGTMRPLDREVEPAFQLQIEARDGGQPALSA 1830
Cdd:pfam00028    4 SVPENAPVGTeVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSS 83


                   ....*....
gi 242397490  1831 TLLVTVTVL 1839
Cdd:pfam00028   84 TATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 595-677 4.57e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.63  E-value: 4.57e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    595 TATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGDVCTTRTLDRDQGPsSFDFTVTAIDGGG--LKSMVYVKVFVADE 672
Cdd:smart00112    1 SATDADSGENGKVTYSI---LSGNDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGppLSSTATVTITVLDV 76


                    ....*
gi 242397490    673 NDNPP 677
Cdd:smart00112   77 NDNAP 81
Cadherin pfam00028
Cadherin domain;
2480-2586 2.59e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 82.35  E-value: 2.59e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2480 YRVAVSEDLPPGSTLLTLEATDADGSrTHATVDYSIISGNRGRVFQLEPRlaevgDGVgpgpqalgcLVLLEPLDFESLT 2559
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLG-PNGRIFYSILGGGPGGNFRIDPD-----TGD---------ISTTKPLDRESIG 65

                           90       100
                   ....*....|....*....|....*..
gi 242397490  2560 QYNLTVAAADRGQPPRSSAVPVTVTVL 2586
Cdd:pfam00028   66 EYELTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2600-2690 2.88e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 81.96  E-value: 2.88e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2600 YRVTVPEDMPVGAELLHVEASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLSRPLDCETQAQHQLVVQAADPAGTH 2679
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 242397490  2680 -FSLVPVTVEVQ 2690
Cdd:pfam00028   81 lSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2392-2473 8.28e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 80.47  E-value: 8.28e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2392 SATDRDSGANGHISYHLASPAEG--FRVDPNNGTLFTTVgamALGHEGPGVVDVVLEARDHGAPGRTAQATVHVQLKDQN 2469
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDglFSIDPETGEITTTK---PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 242397490   2470 DHAP 2473
Cdd:smart00112   78 DNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 161-247 1.57e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 79.70  E-value: 1.57e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    161 ARDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLL 240
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETG-------EITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74


                    ....*..
gi 242397490    241 DINDHAP 247
Cdd:smart00112   75 DVNDNAP 81
Cadherin pfam00028
Cadherin domain;
684-774 1.04e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 77.73  E-value: 1.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   684 YAASLSAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGLQ 763
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|.
gi 242397490   764 AEPIARVNISI 774
Cdd:pfam00028   81 LSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2188-2268 1.51e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 76.62  E-value: 1.51e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2188 ADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNR 2267
Cdd:smart00112    2 ATDADSGENGKVTYSIL-SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 242397490   2268 P 2268
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
2705-2797 1.62e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 76.96  E-value: 1.62e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2705 STSLAENQPPGTLVTTLHAIDGDAGTFGRLRYSLLEavpGPEGReAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAG 2784
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILG---GGPGG-NFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 242397490  2785 --NLSASVTVSVLIT 2797
Cdd:pfam00028   78 gpPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
368-457 7.11e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 75.41  E-value: 7.11e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   368 RVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGE--GHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPP 445
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpgGNFRIDPDTGDIS---TTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 242397490   446 LRAEAAFVLHVT 457
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1234-1306 8.06e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 74.69  E-value: 8.06e-16
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 242397490   1234 QAKDPDEGENGTILYTLT-GPGSELFSLHPHTGELHTAASLVRAERPHYVLTLSAHDQGSPPRSASLQLLVQVL 1306
Cdd:smart00112    1 SATDADSGENGKVTYSILsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2090-2162 9.70e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 74.31  E-value: 9.70e-16
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 242397490   2090 GSNGPITYSILSGNERGIFSIQPSTGAITVRSAegLDFETSPRLRLVLQAESGGAFAFSV---LTLTLQDANDNAP 2162
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKP--LDREEQPEYTLTVEATDGGGPPLSStatVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2295-2367 1.55e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.92  E-value: 1.55e-15
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 242397490   2295 DVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PHEGHANLTVLVEDVNDNVP 2367
Cdd:smart00112    4 DADSGEngKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGggpPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
897-983 2.86e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 73.49  E-value: 2.86e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   897 LPQNTAPGTPIYTLRALDPDSGANSRITFNLLAGG-DGLFTVDPTTGHVRLMGPLGPPGGPAHELEVEARDGGSPPRTSH 975
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*...
gi 242397490   976 FRLRVVIQ 983
Cdd:pfam00028   85 ATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2810-2916 3.79e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 73.50  E-value: 3.79e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 2810 SFHFQVPEGAQRGHSLGHVQATDEDGGADGLVLYSLATSSP--YFGINQTTGALYLRV--DsrapgsgtttsggggrtrR 2885
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKplD------------------R 62

                          90       100       110
                  ....*....|....*....|....*....|.
gi 242397490 2886 EAPRELRLEVVARGPLPGSRSATVPVTVDIT 2916
Cdd:cd11304    63 EEQSSYTLTVTATDGGGPPLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1438-1535 4.43e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 73.12  E-value: 4.43e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1438 LPENPDPGATLYTFRASDADGpGPNSEVRYRLLRQEPPvPALRLDARTGALSAPRGLDRETTPALLLLVEATDRpanASR 1517
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDS-GENGEVTYSIVSGNED-GLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG---GGP 80

                          90
                  ....*....|....*...
gi 242397490 1518 RRAARVSARVFVTDENDN 1535
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 43-133 7.41e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 72.73  E-value: 7.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   43 LQIDEEQPAGTLIGDISA-GLPPGTAPPPMYFISAQEGSGVgtdLAIDEHSGVVRTARVLDRERRDRYRFTAVTPDG--- 118
Cdd:cd11304     4 VSVPENAPPGTVVLTVSAtDPDSGENGEVTYSIVSGNEDGL---FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggp 80

                          90
                  ....*....|....*...
gi 242397490  119 ---ATVEVTVRVADINDH 133
Cdd:cd11304    81 plsSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
2374-2465 9.12e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 71.95  E-value: 9.12e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2374 YQVMMLEHTPPGSAILSVSATDRDSGANGHISYHLASPAEG--FRVDPNNGTLFTTvgaMALGHEGPGVVDVVLEARDHG 2451
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTT---KPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....
gi 242397490  2452 APGRTAQATVHVQL 2465
Cdd:pfam00028   78 GPPLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
577-658 3.74e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.41  E-value: 3.74e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   577 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGDVCTTRTLDRDQgPSSFDFTVTAIDG 656
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSI---LGGGPGGNFRIDPDTGDISTTKPLDRES-IGEYELTVEATDS 76


                   ..
gi 242397490   657 GG 658
Cdd:pfam00028   77 GG 78
Cadherin pfam00028
Cadherin domain;
2169-2261 1.69e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.48  E-value: 1.69e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2169 YVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGSP 2248
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIL-GGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 242397490  2249 ALVGSATLTVMVI 2261
Cdd:pfam00028   80 PLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2067-2155 1.98e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.48  E-value: 1.98e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2067 EAVLRENAPPGTPVISPKAVHS-GGSNGPITYSILSGNERGIFSIQPSTGAITVRSAegLDFETSPRLRLVLQAESGGAF 2145
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKP--LDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|.
gi 242397490  2146 A-FSVLTLTLQ 2155
Cdd:pfam00028   80 PlSSTATVTIT 90
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1020-1097 4.01e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 4.01e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 242397490   1020 APDGSPVTYHLAADGASSPFGLESQSGWLWVRTALDRESQELYTLKVMAVSGSKAELgqqTGTATVRVIILNQNDHSP 1097
Cdd:smart00112    7 SGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPL---SSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2722-2801 4.34e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 4.34e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2722 HAIDGDAGTFGRLRYSLLeavpGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAGNLSASVTVSVLITGEDE 2801
Cdd:smart00112    1 SATDADSGENGKVTYSIL----SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDV 76
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 813-886 4.55e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 4.55e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 242397490    813 GRLGPVTLTLSGGDPRGLFSLDSPSGLLKTLRPLDRElLGPVLELEVRA-GSGTPPVFAVARIRVLLDDVNDNSP 886
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDRE-EQPEYTLTVEAtDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
999-1090 6.63e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 66.94  E-value: 6.63e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   999 YRVDLPSGTTTGTQILQVQAQAPDGSP---VTYHLAADGASSPFGLESQSGWLWVRTALDRESQELYTLKVMAVSGSKae 1075
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngrIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG-- 78

                           90
                   ....*....|....*
gi 242397490  1076 lGQQTGTATVRVIIL 1090
Cdd:pfam00028   79 -PPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 702-775 1.53e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.45  E-value: 1.53e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 242397490    702 HAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGLQAEPIARVNISIV 775
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
Cadherin pfam00028
Cadherin domain;
2277-2360 2.33e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.40  E-value: 2.33e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2277 RVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PHEG 2351
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPngRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSggpPLSS 83


                   ....*....
gi 242397490  2352 HANLTVLVE 2360
Cdd:pfam00028   84 TATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1329-1425 3.07e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 65.03  E-value: 3.07e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1329 VLTVTAAEGLRPGSLLGSVAPQEP--ASVGVLTYTLVGGaDPEGTFALDSASGRLYLARPLDFEAGPAWRaLTVRAEGPG 1406
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPdsGENGEVTYSIVSG-NEDGLFSIDPSTGEITTAKPLDREEQSSYT-LTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 242397490 1407 GAGAR-LLRVQVRVQDENEH 1425
Cdd:cd11304    79 GPPLSsTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 911-984 4.55e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 63.91  E-value: 4.55e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 242397490    911 RALDPDSGANSRITFNLLAGGD-GLFTVDPTTGHVRLMGPLGPPGGPAHELEVEARDGGSPPRTSHFRLRVVIQD 984
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLD 75
Cadherin pfam00028
Cadherin domain;
145-240 9.11e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 63.47  E-value: 9.11e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   145 QIPEHTALGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYDG 224
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTG-------DISTTKPLDRESIGEYELTVEATDS 76

                           90
                   ....*....|....*.
gi 242397490   225 GSPPRRAQALLDVTLL 240
Cdd:pfam00028   77 GGPPLSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1976-2052 1.25e-11

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 63.49  E-value: 1.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1976 LATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARspvalgPQDR------VLFIVATDLGRPARSATGVVV 2048
Cdd:cd11304    16 VLTVSATDPDSGENGEVTYSIVSGNEDGLfSIDPSTGEITTAK------PLDReeqssyTLTVTATDGGGPPLSSTATVT 89


                  ....
gi 242397490 2049 VGIQ 2052
Cdd:cd11304    90 ITVL 93
Cadherin pfam00028
Cadherin domain;
789-878 1.27e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 63.09  E-value: 1.27e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   789 YVFSVPEDVAPGTSVGIIQAHNP-PGRLGPVTLTLSGGDPRGLFSLDSPSGLLKTLRPLDRELLGPVlELEVRA-GSGTP 866
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEY-ELTVEAtDSGGP 79

                           90
                   ....*....|..
gi 242397490   867 PVFAVARIRVLL 878
Cdd:pfam00028   80 PLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 72-135 1.32e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 62.75  E-value: 1.32e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490     72 YFISAQEGSGVgtdLAIDEHSGVVRTARVLDRERRDRYRFTAV------TPDGATVEVTVRVADINDHAP 135
Cdd:smart00112   15 YSILSGNDDGL---FSIDPETGEITTTKPLDREEQPEYTLTVEatdgggPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1452-1537 3.57e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 61.60  E-value: 3.57e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1452 RASDADGpGPNSEVRYRLLRQEPPVPaLRLDARTGALSAPRGLDRETTPALLLLVEATDRpanASRRRAARVSARVFVTD 1531
Cdd:smart00112    1 SATDADS-GENGKVTYSILSGNDDGL-FSIDPETGEITTTKPLDREEQPEYTLTVEATDG---GGPPLSSTATVTITVLD 75


                    ....*.
gi 242397490   1532 ENDNAP 1537
Cdd:smart00112   76 VNDNAP 81
Cadherin pfam00028
Cadherin domain;
1976-2049 3.26e-10

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 59.24  E-value: 3.26e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1976 LATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARspvalgPQDR------VLFIVATDLGRPARSATGVVV 2048
Cdd:pfam00028   15 VLTVTATDPDLGPNGRIFYSILGGGPGGNfRIDPDTGDISTTK------PLDResigeyELTVEATDSGGPPLSSTATVT 88


                   .
gi 242397490  2049 V 2049
Cdd:pfam00028   89 I 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1356-1427 1.21e-09

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 57.36  E-value: 1.21e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 242397490   1356 GVLTYTLVGGaDPEGTFALDSASGRLYLARPLDFEAGPAWRaLTVRAEGPGGAGAR-LLRVQVRVQDENEHAP 1427
Cdd:smart00112   11 GKVTYSILSG-NDDGLFSIDPETGEITTTKPLDREEQPEYT-LTVEATDGGGPPLSsTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
2811-2916 2.87e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 56.54  E-value: 2.87e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  2811 FHFQVPEGAQRGHSLGHVQATDEDGGADGLVLYSLATSSPY--FGINQTTGALYL--RVDsrapgsgtttsggggrtrRE 2886
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTtkPLD------------------RE 62

                           90       100       110
                   ....*....|....*....|....*....|
gi 242397490  2887 APRELRLEVVARGPLPGSRSATVPVTVDIT 2916
Cdd:pfam00028   63 SIGEYELTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
44-127 1.45e-07

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 51.53  E-value: 1.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490    44 QIDEEQPAGTLIGDISAG---LPPGTAPppMYFISAQEGSGVgtdLAIDEHSGVVRTARVLDRERRDRYRFTAV------ 114
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATdpdLGPNGRI--FYSILGGGPGGN---FRIDPDTGDISTTKPLDRESIGEYELTVEatdsgg 78

                           90
                   ....*....|...
gi 242397490   115 TPDGATVEVTVRV 127
Cdd:pfam00028   79 PPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1980-2052 2.32e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 50.81  E-value: 2.32e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   1980 RAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARSPvalgpqDR------VLFIVATDLGRPARSATGVVVVGIQ 2052
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLfSIDPETGEITTTKPL------DReeqpeyTLTVEATDGGGPPLSSTATVTITVL 74
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
 1224-1794 3.24e-06

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 53.34  E-value: 3.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1224 VPPGTLVTTLQAKDPDEGENGTILYTLTGPGSELFSLHPHTGELHTA------ASLVRAERPHYV----------LTLSA 1287
Cdd:COG3321   797 VGPGPVLTGLVRQCLAAAGDAVVLPSLRRGEDELAQLLTALAQLWVAgvpvdwSALYPGRGRRRVplptypfqreDAAAA 876

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1288 HDQGSPPRSASLQLLVQVLPSTRVVESPDLIEADSAATVPVVLTVTAAEGLRPGSLLGSVAPQEPASVGVLTYTLVGGAD 1367
Cdd:COG3321   877 LLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALLALAAAAAAAAAAL 956

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1368 PEGTFALDSASGRLYLARPLDFEAGPAWRALTVRAEGPGGAGARLLRVQVRVQDENEHAPTFARDPLALALPENPDPGAT 1447
Cdd:COG3321   957 AAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLALAALLAAAAAALA 1036

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1448 LYTFRASDADGPGPNSEVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAARVSARV 1527
Cdd:COG3321  1037 AAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAALAAALLLLALLAALA 1116

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1528 FVTDENDNAPVFASPSRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGGDGHFRLHATTGALSVVRPLDREQRAE 1607
Cdd:COG3321  1117 LAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALALAAALAAALAGLAALL 1196

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1608 HVLTVVALDHGSPPRSSTQLLTVSVVDVNDEAPAFPQQEYNVILRENSPPGTSLL---TLKATDPDLGANGQVTYGGVSG 1684
Cdd:COG3321  1197 LAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAaaaLLAALAALALLAAAAGLAALAA 1276

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1685 ESFSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLPPLLTHITVRVTVEDENDHTPTFGNTHLSLEVPEGQDPQTLTT 1764
Cdd:COG3321  1277 AAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALAALAAAVAAALALAAAAAAAAAAAAA 1356

                         570       580       590
                  ....*....|....*....|....*....|
gi 242397490 1765 LRASDPDGGLNGQLQYRILDGDSSGAFALD 1794
Cdd:COG3321  1357 AAAAAALAAAAGAAAAAAALALAALAAAVA 1386
Cadherin pfam00028
Cadherin domain;
1331-1417 1.57e-05

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 45.75  E-value: 1.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490  1331 TVTAAEGLRPGSLLGSVA---PQEPASvGVLTYTLVGGaDPEGTFALDSASGRLYLARPLDFEAgPAWRALTVRAEGPGG 1407
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTatdPDLGPN-GRIFYSILGG-GPGGNFRIDPDTGDISTTKPLDRES-IGEYELTVEATDSGG 78

                           90
                   ....*....|...
gi 242397490  1408 AGAR---LLRVQV 1417
Cdd:pfam00028   79 PPLSstaTVTITV 91
CA_like cd00031
Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1850-1949 1.66e-04

Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.


Pssm-ID: 206635  Cd Length: 98  Bit Score: 43.10  E-value: 1.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1850 VPSYSVEVPEDAPvgTLLLQLQAHDpdDGDNGRVMYYLGAGT---AGAFLLEPTSGELSTATALDREHCASYAFSVTAVD 1926
Cdd:cd00031     1 IPDGSAVEGRSRG--SFRVSIPTDL--IASSGEIIKISAAGKealPSWLHWEPHSGILEGLEKLDREDKGVHYISVSAAS 76

                          90       100
                  ....*....|....*....|...
gi 242397490 1927 GAAAGPLSTTVpITITVRDVNDH 1949
Cdd:cd00031    77 LGANVPQTSSV-FSIEVYDENDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2829-2916 4.61e-04

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 41.18  E-value: 4.61e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490   2829 QATDEDGGADGLVLYSLATSSP--YFGINQTTGALYL--RVDsrapgsgtttsggggrtrREAPRELRLEVVARGPLPGS 2904
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdgLFSIDPETGEITTtkPLD------------------REEQPEYTLTVEATDGGGPP 62

                            90
                    ....*....|..
gi 242397490   2905 RSATVPVTVDIT 2916
Cdd:smart00112   63 LSSTATVTITVL 74
CA_like cd00031
Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2639-2695 1.69e-03

Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.


Pssm-ID: 206635  Cd Length: 98  Bit Score: 40.41  E-value: 1.69e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 242397490 2639 PLGLFELDENSGALRLSRPLDCETQAQHQLVVQAADPAGThfslVPVT-----VEVQDVNDH 2695
Cdd:cd00031    41 LPSWLHWEPHSGILEGLEKLDREDKGVHYISVSAASLGAN----VPQTssvfsIEVYDENDN 98
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 1729-1951 2.52e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 43.88  E-value: 2.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1729 TVRVTVEDENdHTPTfGNTHLSLEVPEGqDPQTLTTlRASDPDGGLngqLQYRILDgDSSGAFALDLTSGEFGTMRPLDR 1808
Cdd:NF038112 1271 TVTVLVRNVN-RAPV-AVAGAPATVDER-STVTLDG-SGTDADGDA---LTYAWTQ-TSGPAVTLTGATTATATFTAPEV 1342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242397490 1809 EVEPAFQLQIEARDGGQpalSATLLVTVTVLDANdHAPVFPVPSySVEVPEDAPVgtlLLQLQAHDPDdgdnGRVMYYLG 1888
Cdd:NF038112 1343 TADTQLTFTLTVSDGTA---SATDTVTVTVRNVN-RAPVANAGA-DQTVDERSTV---TLSGSATDPD----GDALTYAW 1410

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 242397490 1889 AGTAG-AFLLEPTSGELSTATALDREHCASYAFSVTAvdgAAAGPLSTTVPITITVRDVNdHAP 1951
Cdd:NF038112 1411 TQTAGpTVTLTGADTATASFTAPEVAADTELTFQLTV---SADGQASADVTVTVTVRNVN-RAP 1470
CA_like cd00031
Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1687-1740 4.65e-03

Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.


Pssm-ID: 206635  Cd Length: 98  Bit Score: 39.25  E-value: 4.65e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 242397490 1687 FSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLPPLLTHITVRVTVEDENDH 1740
Cdd:cd00031    45 LHWEPHSGILEGLEKLDREDKGVHYISVSAASLGANVPQTSSVFSIEVYDENDN 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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