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Conserved domains on  [gi|256355163|ref|NP_001157820|]
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COX assembly mitochondrial protein 2 homolog [Gallus gallus]

Protein Classification

COX assembly mitochondrial protein( domain architecture ID 10554202)

COX assembly mitochondrial protein is required for mitochondrial cytochrome c oxidase (COX) assembly and respiration

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cmc1 pfam08583
Cytochrome c oxidase biogenesis protein Cmc1 like; Cmc1 is a metallo-chaperone like protein ...
 1-66 5.14e-11

Cytochrome c oxidase biogenesis protein Cmc1 like; Cmc1 is a metallo-chaperone like protein which is known to localize to the inner mitochondrial membrane in Saccharomyces cerevisiae. It is essential for full expression of cytochrome c oxidase and respiration. Cmc1 contains two Cx9C motifs and is able to bind copper(I). Cmc1 is thought to play a role in mitochondrial copper trafficking and transfer to cytochrome c oxidase.


:

Pssm-ID: 400756  Cd Length: 70  Bit Score: 52.34  E-value: 5.14e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256355163   1 MHPDLSPHLHtEECNLIISLLKKCHKEHNVLRFFGHCNDIDREMRKCLKKEYEEKRARNREVRRKI 66
Cdd:pfam08583  1 MHPQLRKKAF-KKCAELIKALAECHKGGRTLKAFGKCNKEKRAMNKCLREYRTDEALRDRERDREI 65
 
Name Accession Description Interval E-value
Cmc1 pfam08583
Cytochrome c oxidase biogenesis protein Cmc1 like; Cmc1 is a metallo-chaperone like protein ...
 1-66 5.14e-11

Cytochrome c oxidase biogenesis protein Cmc1 like; Cmc1 is a metallo-chaperone like protein which is known to localize to the inner mitochondrial membrane in Saccharomyces cerevisiae. It is essential for full expression of cytochrome c oxidase and respiration. Cmc1 contains two Cx9C motifs and is able to bind copper(I). Cmc1 is thought to play a role in mitochondrial copper trafficking and transfer to cytochrome c oxidase.


Pssm-ID: 400756  Cd Length: 70  Bit Score: 52.34  E-value: 5.14e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256355163   1 MHPDLSPHLHtEECNLIISLLKKCHKEHNVLRFFGHCNDIDREMRKCLKKEYEEKRARNREVRRKI 66
Cdd:pfam08583  1 MHPQLRKKAF-KKCAELIKALAECHKGGRTLKAFGKCNKEKRAMNKCLREYRTDEALRDRERDREI 65
 
Name Accession Description Interval E-value
Cmc1 pfam08583
Cytochrome c oxidase biogenesis protein Cmc1 like; Cmc1 is a metallo-chaperone like protein ...
 1-66 5.14e-11

Cytochrome c oxidase biogenesis protein Cmc1 like; Cmc1 is a metallo-chaperone like protein which is known to localize to the inner mitochondrial membrane in Saccharomyces cerevisiae. It is essential for full expression of cytochrome c oxidase and respiration. Cmc1 contains two Cx9C motifs and is able to bind copper(I). Cmc1 is thought to play a role in mitochondrial copper trafficking and transfer to cytochrome c oxidase.


Pssm-ID: 400756  Cd Length: 70  Bit Score: 52.34  E-value: 5.14e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256355163   1 MHPDLSPHLHtEECNLIISLLKKCHKEHNVLRFFGHCNDIDREMRKCLKKEYEEKRARNREVRRKI 66
Cdd:pfam08583  1 MHPQLRKKAF-KKCAELIKALAECHKGGRTLKAFGKCNKEKRAMNKCLREYRTDEALRDRERDREI 65
RRF pfam01765
Ribosome recycling factor; The ribosome recycling factor (RRF / ribosome release factor) ...
 42-75 1.19e-03

Ribosome recycling factor; The ribosome recycling factor (RRF / ribosome release factor) dissociates the ribosome from the mRNA after termination of translation, and is essential bacterial growth. Thus ribosomes are "recycled" and ready for another round of protein synthesis.


Pssm-ID: 460316  Cd Length: 158  Bit Score: 34.72  E-value: 1.19e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 256355163   42 REMRKCLKKEYEEKRARNREVRRKIIDAHKNFEK 75
Cdd:pfam01765  88 KELVKQAKKLAEEAKVAIRNIRRDANDKLKKLEK 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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