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Conserved domains on  [gi|268370032|ref|NP_001161215|]
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schlafen family member 8 isoform 2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA02782 super family cl31504
hypothetical protein; Provisional
45-346 7.32e-37

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PHA02782:

Pssm-ID: 165147 [Multi-domain]  Cd Length: 503  Bit Score: 140.19  E-value: 7.32e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032  45 ITEAACALLNSGGGLIamQMTNKSEHPVEMGQDLEKSLRELIMSpnMQAFFETKQQEDQFYIFVKSwscrpedGSTKPRI 124
Cdd:PHA02782 209 LSTSISALLNSGGGTI--EVTSKEERVDYVLMKRLESIRHLWSV--VYDHFNVVNGKERCYIHMHS-------SNQSPMP 277
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032 125 CSLGSSLYCRSITSKVAMDSREAFEFLKDKKACIKYRPTDDgAPPAKIPRAMCQNSLESNPAFEIFQSKKLEYGQCLLFS 204
Cdd:PHA02782 278 STVKTNLYMKTMGSCLQMDSMEALEYLSELKESGGRSPRPE-LPEFEYPDGVEDTGSIERLAEEFFNRSELQAGESVKFG 356
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032 205 ESTSIEFKQFSTKHVQAYMKNIIPEYISAFANTQGGYLFIGVDDK-RIILGCpkdNVDRDSLKTVANET---ISKVPVFH 280
Cdd:PHA02782 357 NSINVKHTSVSAKQLRTRIRQQLPSILSSFANTEGGYLFIGVDNNtHKVIGF---TVGQDYLKLVENDIekyIKRLRVVH 433
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 268370032 281 FCssKDKDKVSYETRVIDVFQEGN--LYGYLCVIKVEPFCCAVFSEAPISWMVDKEkGVYRLNTEEWV 346
Cdd:PHA02782 434 FC--EKKEDIKYACRFIKVYKPGEetTSTYVCAIKVERCCCAVFADWPESWYMDTS-GIKKYSPDEWV 498
 
Name Accession Description Interval E-value
PHA02782 PHA02782
hypothetical protein; Provisional
45-346 7.32e-37

hypothetical protein; Provisional


Pssm-ID: 165147 [Multi-domain]  Cd Length: 503  Bit Score: 140.19  E-value: 7.32e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032  45 ITEAACALLNSGGGLIamQMTNKSEHPVEMGQDLEKSLRELIMSpnMQAFFETKQQEDQFYIFVKSwscrpedGSTKPRI 124
Cdd:PHA02782 209 LSTSISALLNSGGGTI--EVTSKEERVDYVLMKRLESIRHLWSV--VYDHFNVVNGKERCYIHMHS-------SNQSPMP 277
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032 125 CSLGSSLYCRSITSKVAMDSREAFEFLKDKKACIKYRPTDDgAPPAKIPRAMCQNSLESNPAFEIFQSKKLEYGQCLLFS 204
Cdd:PHA02782 278 STVKTNLYMKTMGSCLQMDSMEALEYLSELKESGGRSPRPE-LPEFEYPDGVEDTGSIERLAEEFFNRSELQAGESVKFG 356
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032 205 ESTSIEFKQFSTKHVQAYMKNIIPEYISAFANTQGGYLFIGVDDK-RIILGCpkdNVDRDSLKTVANET---ISKVPVFH 280
Cdd:PHA02782 357 NSINVKHTSVSAKQLRTRIRQQLPSILSSFANTEGGYLFIGVDNNtHKVIGF---TVGQDYLKLVENDIekyIKRLRVVH 433
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 268370032 281 FCssKDKDKVSYETRVIDVFQEGN--LYGYLCVIKVEPFCCAVFSEAPISWMVDKEkGVYRLNTEEWV 346
Cdd:PHA02782 434 FC--EKKEDIKYACRFIKVYKPGEetTSTYVCAIKVERCCCAVFADWPESWYMDTS-GIKKYSPDEWV 498
AlbA_2 pfam04326
Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.
205-341 6.16e-21

Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.


Pssm-ID: 461263  Cd Length: 116  Bit Score: 87.36  E-value: 6.16e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032  205 ESTSIEFKQFSTKhvqaYMKNIIPEYISAFANTQGGYLFIGVDDKRIILGCPKDNVDrdslktvaNETISKVPVFHFCSS 284
Cdd:pfam04326   1 ESETLEFKESLGK----SSKKKIAKTISAFANTEGGTIVIGVDDTGKIVGVSDDEKD--------TEDLLKNQILDLIKP 68
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 268370032  285 KdkdkvsYETRVIDVFQEGNlygYLCVIKVEPFCCAVFSEAPISWMVDKEKGVYRLN 341
Cdd:pfam04326  69 P------IEVDIEEIEIDGK---YVLVVEIPEGKLKPYYTNKGEVYIRVGSSSRPAS 116
COG2865 COG2865
Predicted transcriptional regulator, contains HTH domain [Transcription];
205-339 5.38e-14

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 442112  Cd Length: 123  Bit Score: 67.99  E-value: 5.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032 205 ESTSIEFKQfstkhvQAYMKNIIPEYISAFANTQGGYLFIGVDDKRIILGCPKDNVDRDSLKTVANETISkvPvfhfcss 284
Cdd:COG2865   11 ESETLEFKE------SLNEPDEILKTVCAFANTEGGTLLIGVDDDGEIVGLDDPDKLLERLENLIADNIS--P------- 75
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 268370032 285 kdkdKVSYETRVIDVfqEGnlyGYLCVIKVEPfccavFSEAPISwmVDKEKGVYR 339
Cdd:COG2865   76 ----PIRPDVEEVEI--DG---KRVLVIEVPP-----GPSKPYY--LKGKGGAYI 114
 
Name Accession Description Interval E-value
PHA02782 PHA02782
hypothetical protein; Provisional
45-346 7.32e-37

hypothetical protein; Provisional


Pssm-ID: 165147 [Multi-domain]  Cd Length: 503  Bit Score: 140.19  E-value: 7.32e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032  45 ITEAACALLNSGGGLIamQMTNKSEHPVEMGQDLEKSLRELIMSpnMQAFFETKQQEDQFYIFVKSwscrpedGSTKPRI 124
Cdd:PHA02782 209 LSTSISALLNSGGGTI--EVTSKEERVDYVLMKRLESIRHLWSV--VYDHFNVVNGKERCYIHMHS-------SNQSPMP 277
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032 125 CSLGSSLYCRSITSKVAMDSREAFEFLKDKKACIKYRPTDDgAPPAKIPRAMCQNSLESNPAFEIFQSKKLEYGQCLLFS 204
Cdd:PHA02782 278 STVKTNLYMKTMGSCLQMDSMEALEYLSELKESGGRSPRPE-LPEFEYPDGVEDTGSIERLAEEFFNRSELQAGESVKFG 356
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032 205 ESTSIEFKQFSTKHVQAYMKNIIPEYISAFANTQGGYLFIGVDDK-RIILGCpkdNVDRDSLKTVANET---ISKVPVFH 280
Cdd:PHA02782 357 NSINVKHTSVSAKQLRTRIRQQLPSILSSFANTEGGYLFIGVDNNtHKVIGF---TVGQDYLKLVENDIekyIKRLRVVH 433
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 268370032 281 FCssKDKDKVSYETRVIDVFQEGN--LYGYLCVIKVEPFCCAVFSEAPISWMVDKEkGVYRLNTEEWV 346
Cdd:PHA02782 434 FC--EKKEDIKYACRFIKVYKPGEetTSTYVCAIKVERCCCAVFADWPESWYMDTS-GIKKYSPDEWV 498
AlbA_2 pfam04326
Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.
205-341 6.16e-21

Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.


Pssm-ID: 461263  Cd Length: 116  Bit Score: 87.36  E-value: 6.16e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032  205 ESTSIEFKQFSTKhvqaYMKNIIPEYISAFANTQGGYLFIGVDDKRIILGCPKDNVDrdslktvaNETISKVPVFHFCSS 284
Cdd:pfam04326   1 ESETLEFKESLGK----SSKKKIAKTISAFANTEGGTIVIGVDDTGKIVGVSDDEKD--------TEDLLKNQILDLIKP 68
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 268370032  285 KdkdkvsYETRVIDVFQEGNlygYLCVIKVEPFCCAVFSEAPISWMVDKEKGVYRLN 341
Cdd:pfam04326  69 P------IEVDIEEIEIDGK---YVLVVEIPEGKLKPYYTNKGEVYIRVGSSSRPAS 116
COG2865 COG2865
Predicted transcriptional regulator, contains HTH domain [Transcription];
205-339 5.38e-14

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 442112  Cd Length: 123  Bit Score: 67.99  E-value: 5.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268370032 205 ESTSIEFKQfstkhvQAYMKNIIPEYISAFANTQGGYLFIGVDDKRIILGCPKDNVDRDSLKTVANETISkvPvfhfcss 284
Cdd:COG2865   11 ESETLEFKE------SLNEPDEILKTVCAFANTEGGTLLIGVDDDGEIVGLDDPDKLLERLENLIADNIS--P------- 75
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 268370032 285 kdkdKVSYETRVIDVfqEGnlyGYLCVIKVEPfccavFSEAPISwmVDKEKGVYR 339
Cdd:COG2865   76 ----PIRPDVEEVEI--DG---KRVLVIEVPP-----GPSKPYY--LKGKGGAYI 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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