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Conserved domains on  [gi|281361340|ref|NP_001163550|]
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uncharacterized protein Dmel_CG7352, isoform C [Drosophila melanogaster]

Protein Classification

trichohyalin-plectin-homology domain domain-containing protein( domain architecture ID 12159040)

trichohyalin-plectin-homology domain (TPH) domain-containing protein similar to meiosis-specific nuclear structural protein 1, trichoplein keratin filament-binding protein, and cilia- and flagella-associated proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 22-359 9.67e-39

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


:

Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 141.59  E-value: 9.67e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   22 LRRDCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLE---AAEVSQERCLLEVRQREKEVALKEEQRRLRESLAE 98
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEErrlDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   99 QMEENRRRRLQEHAQVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQELREWQRAQYNQELSDLVQK 178
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  179 QSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSDERYRQQMQQEQMSRQRTRQE 258
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  259 LDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRRRAHGASLLAMIEDNHRKRAEATAENVQYFDMK 338
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 281361340  339 AKIDAEQEERIKQERLAMLSQ 359
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 22-359 9.67e-39

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 141.59  E-value: 9.67e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   22 LRRDCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLE---AAEVSQERCLLEVRQREKEVALKEEQRRLRESLAE 98
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEErrlDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   99 QMEENRRRRLQEHAQVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQELREWQRAQYNQELSDLVQK 178
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  179 QSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSDERYRQQMQQEQMSRQRTRQE 258
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  259 LDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRRRAHGASLLAMIEDNHRKRAEATAENVQYFDMK 338
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 281361340  339 AKIDAEQEERIKQERLAMLSQ 359
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 16-261 1.09e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 1.09e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  16 RKRRQQLRRDCE---ELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQREKEVALKEEQRRL 92
Cdd:COG1196  199 ERQLEPLERQAEkaeRYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  93 RESLAEQMEENRRRRLQEHAQVmnDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQD-----------MLRSIKENQELR 161
Cdd:COG1196  279 LELELEEAQAEEYELLAELARL--EQDIARLEERRRELEERLEELEEELAELEEELEeleeeleeleeELEEAEEELEEA 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 162 EWQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSDERY 241
Cdd:COG1196  357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                        250       260
                 ....*....|....*....|
gi 281361340 242 RQQMQQEQMSRQRTRQELDR 261
Cdd:COG1196  437 EEEEEEALEEAAEEEAELEE 456
PTZ00121 PTZ00121
MAEBL; Provisional
 9-314 3.76e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 3.76e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    9 KRAEfvERKRRQQLRRDCEELRDLAEQLRLAAISRDIAENL---EEKKRRRQLDIKLEAAEVSQERCLLEVRQRE----- 80
Cdd:PTZ00121 1477 KKAE--EAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAkkaEEAKKADEAKKAEEAKKADEAKKAEEKKKADelkka 1554

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   81 KEVALKEEQRRLRESLAEQMEENRRRRLQEHAQVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQEL 160
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKK 1634

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  161 REWQRAQYNQELSDLVQKQSDMERRKLqleaeRQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDllEAEYTAKSDER 240
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAEELKKAEEENKI-----KAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK--EAEEAKKAEEL 1707

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 281361340  241 YRQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRRRAHGASLL 314
Cdd:PTZ00121 1708 KKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI 1781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-308 7.84e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 7.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340     2 TQEMQDLKRAEFVERKRRQQLRRDCEELRDLAEQLRLAAIsrdiaenlEEKKRRRQLDIKLEAAEVSQERCLLEVRQREK 81
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE--------ELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    82 EVALKEEQRRLRESLAEQMEENRRRRLQEHAQV---MNDRELSLLMQKQIQEEDRAqELEAQRKKLQKRQDMLRSIKENQ 158
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELeaqIEQLKEELKALREALDELRA-ELTLLNEEAANLRERLESLERRI 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   159 ELREWQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSD 238
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   239 ERYRQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKrAEMATRQEEAPDTINQNSEKQLDEYRRRRA 308
Cdd:TIGR02168  914 RRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLT-LEEAEALENKIEDDEEEARRRLKRLENKIK 982
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 22-359 9.67e-39

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 141.59  E-value: 9.67e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   22 LRRDCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLE---AAEVSQERCLLEVRQREKEVALKEEQRRLRESLAE 98
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEErrlDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   99 QMEENRRRRLQEHAQVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQELREWQRAQYNQELSDLVQK 178
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  179 QSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSDERYRQQMQQEQMSRQRTRQE 258
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  259 LDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRRRAHGASLLAMIEDNHRKRAEATAENVQYFDMK 338
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 281361340  339 AKIDAEQEERIKQERLAMLSQ 359
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 16-261 1.09e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 1.09e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  16 RKRRQQLRRDCE---ELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQREKEVALKEEQRRL 92
Cdd:COG1196  199 ERQLEPLERQAEkaeRYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  93 RESLAEQMEENRRRRLQEHAQVmnDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQD-----------MLRSIKENQELR 161
Cdd:COG1196  279 LELELEEAQAEEYELLAELARL--EQDIARLEERRRELEERLEELEEELAELEEELEeleeeleeleeELEEAEEELEEA 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 162 EWQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSDERY 241
Cdd:COG1196  357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                        250       260
                 ....*....|....*....|
gi 281361340 242 RQQMQQEQMSRQRTRQELDR 261
Cdd:COG1196  437 EEEEEEALEEAAEEEAELEE 456
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 16-288 1.13e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 1.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  16 RKRRQQLRRDCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQREKEVALKEEQRRLRES 95
Cdd:COG1196  235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  96 LAEQMEENRRRRLQEHAQVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQDmlrsiKENQELREWQRAQyNQELSDL 175
Cdd:COG1196  315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL-----EAEAELAEAEEEL-EELAEEL 388

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 176 VQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSDERYRQQMQQEQMSRQRT 255
Cdd:COG1196  389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                        250       260       270
                 ....*....|....*....|....*....|...
gi 281361340 256 RQELDRYRQEVKHRKMAEMQMKRAEMATRQEEA 288
Cdd:COG1196  469 LEEAALLEAALAELLEELAEAAARLLLLLEAEA 501
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-261 1.43e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 1.43e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   2 TQEMQDLKRAEFVERKRRQQLRRDCEELRDLAEQL---------RLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERC 72
Cdd:COG1196  252 EAELEELEAELAELEAELEELRLELEELELELEEAqaeeyellaELARLEQDIARLEERRRELEERLEELEEELAELEEE 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  73 LLEVRQREKEVALKEEQRRLRESLAEQMEENRRRRLQEHAQVMNDRELSLLmQKQIQEEDRAQELEAQRKKLQKRQDMLR 152
Cdd:COG1196  332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELEEAEE 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 153 SIKENQELREWQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAE 232
Cdd:COG1196  411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                        250       260
                 ....*....|....*....|....*....
gi 281361340 233 YTAKSDERYRQQMQQEQMSRQRTRQELDR 261
Cdd:COG1196  491 ARLLLLLEAEADYEGFLEGVKAALLLAGL 519
PTZ00121 PTZ00121
MAEBL; Provisional
 9-314 3.76e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 3.76e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    9 KRAEfvERKRRQQLRRDCEELRDLAEQLRLAAISRDIAENL---EEKKRRRQLDIKLEAAEVSQERCLLEVRQRE----- 80
Cdd:PTZ00121 1477 KKAE--EAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAkkaEEAKKADEAKKAEEAKKADEAKKAEEKKKADelkka 1554

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   81 KEVALKEEQRRLRESLAEQMEENRRRRLQEHAQVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQEL 160
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKK 1634

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  161 REWQRAQYNQELSDLVQKQSDMERRKLqleaeRQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDllEAEYTAKSDER 240
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAEELKKAEEENKI-----KAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK--EAEEAKKAEEL 1707

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 281361340  241 YRQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRRRAHGASLL 314
Cdd:PTZ00121 1708 KKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI 1781
PTZ00121 PTZ00121
MAEBL; Provisional
 6-357 1.95e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    6 QDLKRAEFVerKRRQQLRRDCEELRDlAEQLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQREKEVAL 85
Cdd:PTZ00121 1221 EDAKKAEAV--KKAEEAKKDAEEAKK-AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKK 1297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   86 KEEQRRLRESLAEQMEENRRRRLQEHAQVMNDRELSLlmqkQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQELREWQR 165
Cdd:PTZ00121 1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAA----KKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK 1373

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  166 AQYNQElSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLE--AEYTAKSDERYRQ 243
Cdd:PTZ00121 1374 EEAKKK-ADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKkkAEEAKKADEAKKK 1452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  244 QMQQEQMSRQRTRQELDRYRQEVKHR-----------KMAEMQMKRAEMATRQEEA---PDTINQNSEKQLDEYRRRRAH 309
Cdd:PTZ00121 1453 AEEAKKAEEAKKKAEEAKKADEAKKKaeeakkadeakKKAEEAKKKADEAKKAAEAkkkADEAKKAEEAKKADEAKKAEE 1532

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 281361340  310 GASLLAMIEDNHRKRAEATAENVQYFDMKAKIDAEQEERIKQERLAML 357
Cdd:PTZ00121 1533 AKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMAL 1580
PTZ00121 PTZ00121
MAEBL; Provisional
 9-354 1.97e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    9 KRAEfvERKRRQQLRRDCEELRDLAEQLRLAAISRDIAENL----EEKKRRRQLDIKLEAAEVSQE-RCLLEVRQREKEV 83
Cdd:PTZ00121 1385 KKAE--EKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAkkkaEEKKKADEAKKKAEEAKKADEaKKKAEEAKKAEEA 1462

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   84 ALKEEQRRLRESLAEQMEENRR-----RRLQEHAQVMNDRELSLLMQKQIQEEDRAQEL----EAQRKKLQKRQDMLR-- 152
Cdd:PTZ00121 1463 KKKAEEAKKADEAKKKAEEAKKadeakKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAkkadEAKKAEEAKKADEAKka 1542

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  153 -SIKENQELREWQRAQYNQELSDLVQKQSDMERRKLQLEaeRQEIQRKKQEISIRLGQQVLEIENKKRHRDnllldLLEA 231
Cdd:PTZ00121 1543 eEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALR--KAEEAKKAEEARIEEVMKLYEEEKKMKAEE-----AKKA 1615

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  232 EYTAKSDERYRQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRR----- 306
Cdd:PTZ00121 1616 EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAaealk 1695

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 281361340  307 ----RAHGASLLAMIEDNHRKRAEAT--AENVQYFDMKAKIDAEQEERIKQERL 354
Cdd:PTZ00121 1696 keaeEAKKAEELKKKEAEEKKKAEELkkAEEENKIKAEEAKKEAEEDKKKAEEA 1749
PTZ00121 PTZ00121
MAEBL; Provisional
 9-354 2.23e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 2.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    9 KRAEfvERKRRQQLRRDCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDiKLEAAEVSQERCLL---EVRQREKEVAL 85
Cdd:PTZ00121 1309 KKAE--EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD-EAEAAEEKAEAAEKkkeEAKKKADAAKK 1385

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   86 KEEQRRLRESLAEQMEENRRRRlQEHAQVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQELREWQR 165
Cdd:PTZ00121 1386 KAEEKKKADEAKKKAEEDKKKA-DELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  166 AQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSDErYRQQM 245
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE-AKKAE 1543

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  246 QQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRRRAHGASLLAMIEDNHRKRA 325
Cdd:PTZ00121 1544 EKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                         330       340
                  ....*....|....*....|....*....
gi 281361340  326 EATAENVQYFDMKAKIDAEQEERIKQERL 354
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEEL 1652
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-308 7.84e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 7.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340     2 TQEMQDLKRAEFVERKRRQQLRRDCEELRDLAEQLRLAAIsrdiaenlEEKKRRRQLDIKLEAAEVSQERCLLEVRQREK 81
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE--------ELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    82 EVALKEEQRRLRESLAEQMEENRRRRLQEHAQV---MNDRELSLLMQKQIQEEDRAqELEAQRKKLQKRQDMLRSIKENQ 158
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELeaqIEQLKEELKALREALDELRA-ELTLLNEEAANLRERLESLERRI 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   159 ELREWQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSD 238
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   239 ERYRQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKrAEMATRQEEAPDTINQNSEKQLDEYRRRRA 308
Cdd:TIGR02168  914 RRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLT-LEEAEALENKIEDDEEEARRRLKRLENKIK 982
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 9-326 2.52e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.27  E-value: 2.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    9 KRAEFVERKRRQQLRRDCEELRDLAEQLRlaaisrdiaeNLEEKKRRRQLDIKLEAAEVSQERCLLEVRQREKEVALKEE 88
Cdd:pfam17380 288 QQQEKFEKMEQERLRQEKEEKAREVERRR----------KLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEE 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   89 QRRLRESLAEQ---MEENRRRRLQEhaqvmndrelsLLMQKQIQEEDRAQELEAQRKklQKRQDMLRSIKENQELREWQR 165
Cdd:pfam17380 358 RKRELERIRQEeiaMEISRMRELER-----------LQMERQQKNERVRQELEAARK--VKILEEERQRKIQQQKVEMEQ 424

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  166 AQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISiRLGQQVLEIENKKRHRDnllldlleaeytaksdERYRQQM 245
Cdd:pfam17380 425 IRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVE-RLRQQEEERKRKKLELE----------------KEKRDRK 487

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  246 QQEQMSRQRTRQELdryrqEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRRRAHGASLLAMIEDNHRKRA 325
Cdd:pfam17380 488 RAEEQRRKILEKEL-----EERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKAT 562


                  .
gi 281361340  326 E 326
Cdd:pfam17380 563 E 563
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 6-299 3.33e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.88  E-value: 3.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    6 QDLKRAEFVERKRRQQLRRDCEElrdlAEQLRLAAISRDIA----------ENLEEKKRRRQLDIKLEAAEVSQERCLLE 75
Cdd:pfam17380 298 QERLRQEKEEKAREVERRRKLEE----AEKARQAEMDRQAAiyaeqermamERERELERIRQEERKRELERIRQEEIAME 373

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   76 VRQREKEVALKEEQRRLRESLAEQMEENRRRRLQEH-------------AQVMNDRELSLLMQKQIQEEDRAQELEAQRK 142
Cdd:pfam17380 374 ISRMRELERLQMERQQKNERVRQELEAARKVKILEEerqrkiqqqkvemEQIRAEQEEARQREVRRLEEERAREMERVRL 453

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  143 KLQKRQDMLRSIKENQELREWQRAQYNQELSDlvQKQSDMERRKLqLEAERQEIQRKkqeisirlgqqVLEIENKKRhrd 222
Cdd:pfam17380 454 EEQERQQQVERLRQQEEERKRKKLELEKEKRD--RKRAEEQRRKI-LEKELEERKQA-----------MIEEERKRK--- 516

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281361340  223 nllldLLEAEYTAKSDERYRQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQ 299
Cdd:pfam17380 517 -----LLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKAR 588
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 87-359 5.28e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 5.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  87 EEQRRLRESLAEQMEENRR-RRLQEHAQVmndRELSLLMQKQIQEEDRAQELEAQRKKLQKR----QDMLRSIKENQELR 161
Cdd:COG1196  196 GELERQLEPLERQAEKAERyRELKEELKE---LEAELLLLKLRELEAELEELEAELEELEAEleelEAELAELEAELEEL 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 162 EWQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSDERY 241
Cdd:COG1196  273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 242 RQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTinQNSEKQLDEYRRRRAHGASLLAMIEDNH 321
Cdd:COG1196  353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL--EELEEAEEALLERLERLEEELEELEEAL 430

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 281361340 322 RKRAEATAENVQYFDMKAKIDAEQEERIKQERLAMLSQ 359
Cdd:COG1196  431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468
PTZ00121 PTZ00121
MAEBL; Provisional
 3-355 8.15e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 8.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    3 QEMQDLKRAEFVERKRRQQLRRDCEELRDLAEQLRLAAISRDIAENLEEKK------RRRQLDIKLEAAEVSQERCLLEV 76
Cdd:PTZ00121 1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEarmahfARRQAAIKAEEARKADELKKAEE 1288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   77 RQREKEVALKEEQRRLRESLAEQMEENRRRRLQEHAQVMNDRELSLlmqkQIQEEDRAQELEAQRKKLQKRQDMLRSIKE 156
Cdd:PTZ00121 1289 KKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAA----KKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  157 NQELREWQRAQYNQElSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLL--EAEYT 234
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKK-ADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkKAEEA 1443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  235 AKSDERYRQQMQQEQMSRQRTRQELDRYRQEVKHR----KMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRRRAHG 310
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKaeeaKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 281361340  311 ASLLAMIEDNHRKRAEATAENVQYFDMKAKID----AEQEERIKQERLA 355
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAKKAEEKKKADELKKAEelkkAEEKKKAEEAKKA 1572
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 73-214 8.75e-05

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 44.46  E-value: 8.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   73 LLEVRQREK------EVALKEEQRRlRESLAEQMEENRRRRLQEHAQVMNDRELSLLMQKQIQE--EDRAQELEAQRKKL 144
Cdd:pfam09726 456 AVSAKQKDKqtvqqlEKRLKAEQEA-RASAEKQLAEEKKRKKEEEATAARAVALAAASRGECTEslKQRKRELESEIKKL 534

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  145 QK----RQDMLRSIK-ENQELREWQRAQYNQE-----LSDLVQKQSDME-------RRKLQL-----EAERQ------EI 196
Cdd:pfam09726 535 THdiklKEEQIRELEiKVQELRKYKESEKDTEvlmsaLSAMQDKNQHLEnslsaetRIKLDLfsalgDAKRQleiaqgQI 614

                         170
                  ....*....|....*...
gi 281361340  197 QRKKQEIsIRLGQQVLEI 214
Cdd:pfam09726 615 YQKDQEI-KDLKQKIAEV 631
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
79-269 2.79e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   79 REKEVALKEEQRRLRESLAEQmeENRRRRLQEHAQVMNDRELSLLMQKQIQEED--------RAQELEAQRKKLQKRQDM 150
Cdd:COG4913   609 RAKLAALEAELAELEEELAEA--EERLEALEAELDALQERREALQRLAEYSWDEidvasaerEIAELEAELERLDASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  151 LRSIKEnqelrewQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHR-DNLLLDLL 229
Cdd:COG4913   687 LAALEE-------QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALlEERFAAAL 759

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 281361340  230 EAEYTAKSDERYRQQMQQEQMSRQRTRQELDRYRQEVKHR 269
Cdd:COG4913   760 GDAVERELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
PTZ00121 PTZ00121
MAEBL; Provisional
 3-285 4.35e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 4.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    3 QEMQDLKRAEFVERKRRQQLRRDCEELRDlAEQLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQREK- 81
Cdd:PTZ00121 1531 EEAKKADEAKKAEEKKKADELKKAEELKK-AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKa 1609

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   82 EVALKEEQRRLRESLAEQMEENRRRRLQehaqvmndrelslLMQKQIQEEDRAQEL--EAQRKKLQKRQDMLRSIKENQE 159
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEELKKAEEEKKKVEQ-------------LKKKEAEEKKKAEELkkAEEENKIKAAEEAKKAEEDKKK 1676

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  160 LREWQRAQYNQELSDLVQKQSDMERRKL-QLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNlllDLLEAEyTAKSD 238
Cdd:PTZ00121 1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAeELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE---DKKKAE-EAKKD 1752

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 281361340  239 ERYRQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMATRQ 285
Cdd:PTZ00121 1753 EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
PRK12704 PRK12704
phosphodiesterase; Provisional
 90-216 4.52e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  90 RRLRESLAEQMEENRRRRLQEhaqvmndrelsllMQKQIQEEDRAQELEAQRKKLQKRQDMLRSIKE-NQELREWQR--- 165
Cdd:PRK12704  26 KKIAEAKIKEAEEEAKRILEE-------------AKKEAEAIKKEALLEAKEEIHKLRNEFEKELRErRNELQKLEKrll 92

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 281361340 166 ---AQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIEN 216
Cdd:PRK12704  93 qkeENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELER 146
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
3-203 4.56e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    3 QEMQDLKRA-EFVERKRRQ-----QLRRDCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERclLEV 76
Cdd:COG4913   232 EHFDDLERAhEALEDAREQiellePIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELAR--LEA 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   77 RQREKEVALKEEQRRLREsLAEQMEENRRRRLQEhaqvmndrelsllMQKQI-QEEDRAQELEAQRKKLQKRQDML---- 151
Cdd:COG4913   310 ELERLEARLDALREELDE-LEAQIRGNGGDRLEQ-------------LEREIeRLERELEERERRRARLEALLAALglpl 375

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 281361340  152 ----RSIKENQELREWQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEI 203
Cdd:COG4913   376 pasaEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431
PTZ00121 PTZ00121
MAEBL; Provisional
 47-348 5.44e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 5.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   47 ENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQREKEVALKEEQRRLREslAEQMEENRRRRLQEHAQVMNDRELSLLMQK 126
Cdd:PTZ00121 1091 EATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAED--ARKAEEARKAEDAKRVEIARKAEDARKAEE 1168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  127 QIQEEDRAQELEAQRKKLQKRQDMLRSIKENQELREWQRAQYNQELSDL--VQKQSDMERRKLQLEAERQEIQRKKQEiS 204
Cdd:PTZ00121 1169 ARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEArkAEDAKKAEAVKKAEEAKKDAEEAKKAE-E 1247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  205 IRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSDE--RYRQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMA 282
Cdd:PTZ00121 1248 ERNNEEIRKFEEARMAHFARRQAAIKAEEARKADElkKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEA 1327

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 281361340  283 TRQEEAPDTINQNSEKQlDEYRRRRAHGASLLAMIEDNHRKRAEATAENVQYFDMKAKIDAEQEER 348
Cdd:PTZ00121 1328 KKKADAAKKKAEEAKKA-AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 6-329 1.71e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.81  E-value: 1.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340     6 QDLKRAEFVERKRRQQLR------RDCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQR 79
Cdd:TIGR02168  186 ENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    80 EKEValkEEQRRLRESLAEQMEEnRRRRLQEHAQVMNDRElsllMQKQIQEEdRAQELEAQRKKLQKRQDMLRSikenqe 159
Cdd:TIGR02168  266 EEKL---EELRLEVSELEEEIEE-LQKELYALANEISRLE----QQKQILRE-RLANLERQLEELEAQLEELES------ 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   160 lrewQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAeytAKSDE 239
Cdd:TIGR02168  331 ----KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL---NNEIE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   240 RYRQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRRRRAHGASLLAMIED 319
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483

                          330
                   ....*....|
gi 281361340   320 NHRKRAEATA 329
Cdd:TIGR02168  484 LAQLQARLDS 493
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1-297 2.40e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.05  E-value: 2.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340     1 MTQEMQDLKRAEFVERKRRQQLRRDCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQRE 80
Cdd:TIGR02169  655 MTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK 734

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    81 KEVALKEEQRRLREslAEQMEENRRRRLQEHAQVMNDRELSLlmqKQIQEEDRAQELEAQRKKLQKRQDMLRSIKEnqEL 160
Cdd:TIGR02169  735 LKERLEELEEDLSS--LEQEIENVKSELKELEARIEELEEDL---HKLEEALNDLEARLSHSRIPEIQAELSKLEE--EV 807

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   161 REWQRAqynqeLSDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLLEAEYTAKSDER 240
Cdd:TIGR02169  808 SRIEAR-----LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES 882

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 281361340   241 YRQQMQQEQMSRQRTRQELDRYRQEVKhrkmAEMQMKRAEMATRQEEAPDTINQNSE 297
Cdd:TIGR02169  883 RLGDLKKERDELEAQLRELERKIEELE----AQIEKKRKRLSELKAKLEALEEELSE 935
DUF4175 pfam13779
Domain of unknown function (DUF4175);
18-297 2.50e-03

Domain of unknown function (DUF4175);


Pssm-ID: 463981 [Multi-domain]  Cd Length: 833  Bit Score: 39.97  E-value: 2.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   18 RRQQLRRDCEELRDLAEQLRlaaisrDIAENLEE------KKRRRQLDIKLEAA---EVSQErcllEVRQREKEvaLKEE 88
Cdd:pfam13779 454 ARLELARSDEALDEVADLLW------ELALRIEDgdlsdaERRLRAAQERLSEAlerGASDE----EIAKLMQE--LREA 521

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   89 QRRLRESLAEQMEEN---RRRRLQEHAQVMNDRELSLLMQkQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQelREWQR 165
Cdd:pfam13779 522 LDDYMQALAEQAQQNpqdLQQPDDPNAQEMTQQDLQRMLD-RIEELARSGRRAEAQQMLSQLQQMLENLQAGQ--PQQQQ 598

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  166 AQYNQELSDLVQKQSDMERRKLQLeaeRQEIQRKKQEISIRLGQQvlEIENKKRHRDNLLLDLLEAEYTAKSDERYRQQM 245
Cdd:pfam13779 599 QQGQSEMQQAMDELGDLLREQQQL---LDETFRQLQQQGGQQQGQ--PGQQGQQGQGQQPGQGGQQPGAQMPPQGGAEAL 673

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281361340  246 QQEQMSRQRTRQELDRYRQEVKHR---------KMAEMQMKRAEMATRQEEAPDTINQNSE 297
Cdd:pfam13779 674 GDLAERQQALRRRLEELQDELKELggkepgqalGDAGRAMRDAEEALGQGDLAGAVDAQGR 734
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 78-352 2.66e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.11  E-value: 2.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   78 QREKEVALKEEQRRLRESLAEQMEENRRRRLQEHA----QVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQdmLRS 153
Cdd:pfam17380 287 RQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAekarQAEMDRQAAIYAEQERMAMERERELERIRQEERKRE--LER 364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  154 IKENQELREWQRAQYNQELSdlVQKQSDMERRKLQLEAERQeIQRKKQEISIRLGQQVLEIENKKRHRDNllLDLLEAEY 233
Cdd:pfam17380 365 IRQEEIAMEISRMRELERLQ--MERQQKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRAEQEE--ARQREVRR 439

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  234 TAKSDERYRQQMQQEQMSRQrtrQELDRYRQEVKHRKMAEMQMKRAEmaTRQEEAPDTINQNSEKQLDEYRRRRAHGASL 313
Cdd:pfam17380 440 LEEERAREMERVRLEEQERQ---QQVERLRQQEEERKRKKLELEKEK--RDRKRAEEQRRKILEKELEERKQAMIEEERK 514

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 281361340  314 LAMIEDNHRKRAEATAENVQyfdmkaKIDAEQEERIKQE 352
Cdd:pfam17380 515 RKLLEKEMEERQKAIYEEER------RREAEEERRKQQE 547
COG4487 COG4487
Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];
14-215 3.68e-03

Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];


Pssm-ID: 443580 [Multi-domain]  Cd Length: 425  Bit Score: 39.16  E-value: 3.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  14 VERKRRQQLRRDCEELRDLAEQLRLAaisrdIAENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQREKEVALKEEQRRLR 93
Cdd:COG4487   23 IVKQRRAEFEKELAERLADAAKREAA-----LELAEAKAKAQLQEQVAEKDAEIAELRARLEAEERKKALAVAEEKEKEL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  94 ESLAEQMEENRRRRLQEHAQVMNdrelslLMQKQIQEEDRAQELEAQRKKlqKRQDMLRSIKENQELREWQRAQYNQELS 173
Cdd:COG4487   98 AALQEALAEKDAKLAELQAKELE------LLKKERELEDAKREAELTVEK--ERDEELDELKEKLKKEEEEKQLAEKSLK 169

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 281361340 174 DLvQKQSDMERRKLQLEaerqEIQRKKQEISIRLGQQVLEIE 215
Cdd:COG4487  170 VA-EYEKQLKDMQEQIE----ELKRKKEQGSTQLQGEVLELE 206
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 6-330 3.73e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 39.67  E-value: 3.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340     6 QDLKRAEFVERKRRQQLRR------DCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERCLLEVRQR 79
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERlrrereKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISEL 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    80 EKEVALKEEQRRLRESLAEQMEENRRRRLQEHAQVMNDrELSLLMQKQIQEEDRAQELEAQRKKLQKRQDMLRSIKEN-- 157
Cdd:TIGR02169  264 EKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEA-EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEle 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   158 QELREWQ--RAQYNQELSDLVQKQSDmerrklqLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLLLDLleaeyta 235
Cdd:TIGR02169  343 REIEEERkrRDKLTEEYAELKEELED-------LRAELEEVDKEFAETRDELKDYREKLEKLKREINELKREL------- 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   236 ksdERYRQQMQQEQMSRQRTRQELDRYRQEVKHRKmAEMQMKRAEMATrQEEAPDTINQNSEKQLDEYRRRRAHGASLLA 315
Cdd:TIGR02169  409 ---DRLQEELQRLSEELADLNAAIAGIEAKINELE-EEKEDKALEIKK-QEWKLEQLAADLSKYEQELYDLKEEYDRVEK 483

                          330
                   ....*....|....*
gi 281361340   316 MIEDNHRKRAEATAE 330
Cdd:TIGR02169  484 ELSKLQRELAEAEAQ 498
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 8-203 4.05e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.53  E-value: 4.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   8 LKRAEFVERKRRQQLRRDCEELRDLAEQLRLAAISRDIAENLEEKKRRRQLDIKLEAAEVSQERcLLEVRQREKEVALKE 87
Cdd:COG1196  582 IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR-LREVTLEGEGGSAGG 660

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  88 EQRRLRESLAEQMEENRRRRLQEHAQVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQELREWQRAQ 167
Cdd:COG1196  661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 281361340 168 YNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEI 203
Cdd:COG1196  741 LLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 130-227 4.40e-03

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 38.89  E-value: 4.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 130 EEDRAQELEAQRKKLQKRQDMLRsikenqELREW-QRAQYNQelSDLVQKQSdmerRKLQLEA-ERQEIQRKKQEISI-- 205
Cdd:COG0488  238 LEQRAERLEQEAAAYAKQQKKIA------KEEEFiRRFRAKA--RKAKQAQS----RIKALEKlEREEPPRRDKTVEIrf 305

                         90       100
                 ....*....|....*....|....*..
gi 281361340 206 ----RLGQQVLEIEN-KKRHRDNLLLD 227
Cdd:COG0488  306 pppeRLGKKVLELEGlSKSYGDKTLLD 332
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 125-329 5.97e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.59  E-value: 5.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 125 QKQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQELREWQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEIS 204
Cdd:COG4942   24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 205 IRLGQQVLEIENKKRHRDNLLL----DLLEAEYTAKSDERYRQQMQQEQMSRQRTRQELDRYRQEVKHRK------MAEM 274
Cdd:COG4942  104 EELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERaelealLAEL 183

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281361340 275 QMKRAEMATRQEEAPDTINQNS------EKQLDEYRRRRAHGASLLAMIEDNHRKRAEATA 329
Cdd:COG4942  184 EEERAALEALKAERQKLLARLEkelaelAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
PTZ00121 PTZ00121
MAEBL; Provisional
 3-355 7.34e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.58  E-value: 7.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340    3 QEMQDLKRAEFVERKRRQQLRRDCEELRDlAEQLRLAAISRDIAENLEEKKRRRQLDIK-LEAAEVSQE-RCLLEVRQRE 80
Cdd:PTZ00121 1119 EAKKKAEDARKAEEARKAEDARKAEEARK-AEDAKRVEIARKAEDARKAEEARKAEDAKkAEAARKAEEvRKAEELRKAE 1197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340   81 kEVALKEEQRRLR-----ESLAEQMEENRRRRLQEHAQVMNDRELSLLMQKQIQEEDRAQELEAQRKKLQKRQDMLRS-- 153
Cdd:PTZ00121 1198 -DARKAEAARKAEeerkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAee 1276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  154 ------IKENQELREWQRAQYNQEL--SDLVQKQSDMERRKLQLEAERQEIQRKKQEISIRLGQQVLEIENKKRHRDNLL 225
Cdd:PTZ00121 1277 arkadeLKKAEEKKKADEAKKAEEKkkADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAA 1356

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340  226 LDLLEAEYTAKSDERyrqQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMATRQEEAPDTINQNSEKQLDEYRR 305
Cdd:PTZ00121 1357 DEAEAAEEKAEAAEK---KKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA 1433

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 281361340  306 RRAHGASLLAMIEDNHRKRAEAT--AENVQYFDMKAKIDAEQEERIKQERLA 355
Cdd:PTZ00121 1434 DEAKKKAEEAKKADEAKKKAEEAkkAEEAKKKAEEAKKADEAKKKAEEAKKA 1485
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
125-350 9.81e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 37.96  E-value: 9.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 125 QKQIQEEDRAQELEAQRKKLQKRQDMLRSIKENQELREWQRAQYNQELSDLVQKQSDMERRKLQLEAERQEIQRKKQEIS 204
Cdd:COG4372   56 QAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLE 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281361340 205 IRLGQQVLEIENKKRhrdnlLLDLLEAEYTAKSDERYRQQMQQEQMSRQRTRQELDRYRQEVKHRKMAEMQMKRAEMATR 284
Cdd:COG4372  136 AQIAELQSEIAEREE-----ELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIE 210

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 281361340 285 QEEAPDTINQNSEKQLDEYRRRRAHGASLLAMIEDNHRKRAEATAENVQYFDMKAKIDAEQEERIK 350
Cdd:COG4372  211 SLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEE 276
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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