|
Name |
Accession |
Description |
Interval |
E-value |
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
393-1020 |
0e+00 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 596.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 393 SLPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVG 472
Cdd:COG1643 9 DLPVSAVLPELLAALRAHQVVVLAAPPGAGKTTQLPLALLELGWGAGGRIGMLEPRRLAARAAAERMAEELGEPVGETVG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 473 YSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDI-ARFRPDLKLLISSATMDA 551
Cdd:COG1643 89 YRVRFEDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADLLLALLLDLqPALRPDLKLLVMSATLDA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 552 EKFSDYFDTAPIFSFPGRRYPVEINYT--SAPEADYMDAAIVTILTIHvREPLGDILVFFTGQEEIETAEEILKHRIRgl 629
Cdd:COG1643 169 ERFARLLGDAPVIESSGRTYPVEVRYRplPADERDLEDAVADAVREAL-AEEPGDILVFLPGEREIRRTAEALRGRLP-- 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 630 gtkiRELIICPIYANLPSELQAKIFEPTPEGARKVVLATNIAETSLTIDGIKYVVDPGFSKMKSYNPRTGMESLLITPIS 709
Cdd:COG1643 246 ----PDTEILPLYGRLSAAEQDRAFAPAPHGRRRIVLATNIAETSLTVPGIRYVIDSGLARIPRYDPRSGVTRLPTERIS 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 710 KASATQRAGRAGRTSPGKCYRLYTAFNYNNdLEENTVPEVQRTNLASVVLALKSLGIHDLINFDFMDPPPAEALVKSLEL 789
Cdd:COG1643 322 QASANQRAGRAGRLAPGICYRLWSEEDFAR-RPAFTDPEILRADLASLILELAAWGLGDPEDLPFLDPPPARAIADARAL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 790 LFALGALNKLGELTKAGRRMAEFPLDPMLSKMIVVSDKYKCSDEIISIAAMLSIGGsifyrPKDKQVHADnarmnFHtgn 869
Cdd:COG1643 401 LQELGALDADGRLTPLGRALARLPLDPRLARMLLAAAELGCLREAAILAALLSERD-----PRRGAAGSD-----LL--- 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 870 vgdhiALLKVYSSWKETNfstqwcyENYIQVRSMKRARDIRDQlegLLERVEIDISSNLNELDSVRKSIVAGFFPHTAKL 949
Cdd:COG1643 468 -----ARLNLWRRLREQQ-------REFLSYLRLREWRDLARQ---LRRLLGEGANEEPADYEAIGLLLALAYPDRIARR 532
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334182986 950 QKN-GSYRTVKhpQT-VHIHPNSGLSQvlPRWVVYHELVLTSKEY-MRQVTELKPEWLIELAPHyyQLKDVEDA 1020
Cdd:COG1643 533 RGEgGRYLLAR--GRgAALFPGSPLAK--KEWLVAAELVGGAAEArIRLAAPIDPEWLEELAAH--LIKRYSEP 600
|
|
| DEAH_box_HrpA |
TIGR01967 |
RNA helicase HrpA; This model represents HrpA, one of two related but uncharacterized DEAH-box ... |
367-1010 |
1.07e-158 |
|
RNA helicase HrpA; This model represents HrpA, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria and a few high-GC Gram-positive bacteria. HrpA is about 1300 amino acids long, while its paralog HrpB, also uncharacterized, is about 800 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. The HrpA/B homolog from Borrelia is 500 amino acids shorter but appears to be derived from HrpA rather than HrpB. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273900 [Multi-domain] Cd Length: 1283 Bit Score: 502.76 E-value: 1.07e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 367 DAMDAKQKSQDLAEK--TALEELQEVRRSLPIYTYRDQL---------LKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAG 435
Cdd:TIGR01967 28 DQDRAIAALAKFRERidAACDKVEARRQAVPEIRYPDNLpvsakrediAEAIAENQVVIIAGETGSGKTTQLPKICLELG 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 436 YTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVGYSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDE 515
Cdd:TIGR01967 108 RGSHGLIGHTQPRRLAARTVAQRIAEELGTPLGEKVGYKVRFHDQVSSNTLVKLMTDGILLAETQQDRFLSRYDTIIIDE 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 516 AHERTLSTDILFGLVKDIARFRPDLKLLISSATMDAEKFSDYFDTAPIFSFPGRRYPVEINY------TSAPEADYMDAA 589
Cdd:TIGR01967 188 AHERSLNIDFLLGYLKQLLPRRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYrplveeQEDDDLDQLEAI 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 590 IVTILTIhVREPLGDILVFFTGQEEI-ETAEEILKHRIRGLGtkireliICPIYANLPSELQAKIFEptPEGARKVVLAT 668
Cdd:TIGR01967 268 LDAVDEL-FAEGPGDILIFLPGEREIrDAAEILRKRNLRHTE-------ILPLYARLSNKEQQRVFQ--PHSGRRIVLAT 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 669 NIAETSLTIDGIKYVVDPGFSKMKSYNPRTGMESLLITPISKASATQRAGRAGRTSPGKCYRLYTAFNYNNDlEENTVPE 748
Cdd:TIGR01967 338 NVAETSLTVPGIHYVIDTGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVAPGICIRLYSEEDFNSR-PEFTDPE 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 749 VQRTNLASVVLALKSLGIHDLINFDFMDPPPAEALVKSLELLFALGALNK---LGELTKAGRRMAEFPLDPMLSKMIVVS 825
Cdd:TIGR01967 417 ILRTNLASVILQMLALRLGDIAAFPFIEAPDPRAIRDGFRLLEELGALDDdeaEPQLTPIGRQLAQLPVDPRLARMLLEA 496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 826 DKYKCSDEIISIAAMLSIgGSIFYRPKDKQVHADNARMNFHTGNvGDHIALLKVYSSWKE------TNFSTQWC---YEN 896
Cdd:TIGR01967 497 HRLGCLQEVLIIASALSI-QDPRERPMEKQQAADQAHARFKDPR-SDFLSRVNLWRHIEEqrqalsANQFRNACrkqYLN 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 897 YIQVRSMkraRDIRDQLEGLLERVEIDISSNLNELDSVRKSIVAGFFPHTAKLQKNGSYRTVKHpQTVHIHPNSGLSQVL 976
Cdd:TIGR01967 575 YLRVREW---QDIYRQLTQVVKELGLKLNEEPADYDAIHKALLSGLLSQIGMKDEKHEYDGARG-RKFHIFPGSPLFKKP 650
|
650 660 670
....*....|....*....|....*....|....
gi 334182986 977 PRWVVYHELVLTSKEYMRQVTELKPEWLIELAPH 1010
Cdd:TIGR01967 651 PKWVMAAELVETSKLYARLVAKIEPEWVEPVAGH 684
|
|
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
393-1010 |
4.93e-151 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 482.64 E-value: 4.93e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 393 SLPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVG 472
Cdd:PRK11131 72 NLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICLELGRGVKGLIGHTQPRRLAARTVANRIAEELETELGGCVG 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 473 YSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATMDAE 552
Cdd:PRK11131 152 YKVRFNDQVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFILGYLKELLPRRPDLKVIITSATIDPE 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 553 KFSDYFDTAPIFSFPGRRYPVEINYTS-APEADYMD----AAIVTILTIHVREPLGDILVFFTGQEEI-ETAEEILKhri 626
Cdd:PRK11131 232 RFSRHFNNAPIIEVSGRTYPVEVRYRPiVEEADDTErdqlQAIFDAVDELGREGPGDILIFMSGEREIrDTADALNK--- 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 627 RGLgtkiRELIICPIYANLPSELQAKIFEptPEGARKVVLATNIAETSLTIDGIKYVVDPGFSKMKSYNPRTGMESLLIT 706
Cdd:PRK11131 309 LNL----RHTEILPLYARLSNSEQNRVFQ--SHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIE 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 707 PISKASATQRAGRAGRTSPGKCYRLYTAFNYNNDlEENTVPEVQRTNLASVVLALKSLGIHDLINFDFMDPPPAEALVKS 786
Cdd:PRK11131 383 PISQASANQRKGRCGRVSEGICIRLYSEDDFLSR-PEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDG 461
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 787 LELLFALGALNK-----LGELTKAGRRMAEFPLDPMLSKMIVVSDKYKCSDEIISIAAMLSIGGSiFYRPKDKQVHADNA 861
Cdd:PRK11131 462 VRLLEELGAITTdeqasAYKLTPLGRQLAQLPVDPRLARMVLEAQKHGCVREVMIITSALSIQDP-RERPMDKQQASDEK 540
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 862 RMNFHTGNvGDHIALLKVYSSWKE-------TNFSTQwC---YENYIQVRSMKrarDIRDQLEGLLERVEIDISSNLNEL 931
Cdd:PRK11131 541 HRRFADKE-SDFLAFVNLWNYLQEqqkalssNQFRRL-CrtdYLNYLRVREWQ---DIYTQLRQVVKELGIPVNSEPAEY 615
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 932 DSVRKSIVAGFFPHTA-KLQKNGSYRTVKHPQtVHIHPNSGLSQVLPRWVVYHELVLTSKEYMRQVTELKPEWLIELAPH 1010
Cdd:PRK11131 616 REIHTALLTGLLSHIGmKDAEKQEYTGARNAR-FSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIEPEWIEPLAQH 694
|
|
| DEXHc_DHX16 |
cd17974 |
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably ... |
394-566 |
1.14e-117 |
|
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably involved in pre-mRNA splicing. DHX16 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350732 [Multi-domain] Cd Length: 174 Bit Score: 358.35 E-value: 1.14e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRG-KVGCTQPRRVAAMSVAARVAQEMGVKLGHEVG 472
Cdd:cd17974 1 LPVYPYRDDLLAAVKEHQVLIIVGETGSGKTTQIPQYLHEAGYTKGGgKIGCTQPRRVAAMSVAARVAEEMGVKLGNEVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 473 YSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATMDAE 552
Cdd:cd17974 81 YSIRFEDCTSEKTVLKYMTDGMLLREFLTEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPDLKLLISSATMDAE 160
|
170
....*....|....
gi 334182986 553 KFSDYFDTAPIFSF 566
Cdd:cd17974 161 KFSAFFDDAPIFRI 174
|
|
| DEAH_box_HrpB |
TIGR01970 |
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but ... |
394-823 |
2.32e-109 |
|
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273901 [Multi-domain] Cd Length: 819 Bit Score: 359.08 E-value: 2.32e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIP-QYLHEAGYTkrGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVG 472
Cdd:TIGR01970 1 LPIHAVLPALRDALAAHPQVVLEAPPGAGKSTAVPlALLDAPGIG--GKIIMLEPRRLAARSAAQRLASQLGEAVGQTVG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 473 YSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDI-ARFRPDLKLLISSATMDA 551
Cdd:TIGR01970 79 YRVRGENKVSRRTRLEVVTEGILTRMIQDDPELDGVGALIFDEFHERSLDADLGLALALDVqSSLREDLKILAMSATLDG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 552 EKFSDYFDTAPIFSFPGRRYPVEINYTSAPEADYMDAAIVTILTIHVREPLGDILVFFTGQEEIETAEEILKHRIRGlgt 631
Cdd:TIGR01970 159 ERLSSLLPDAPVVESEGRSFPVEIRYLPLRGDQRLEDAVSRAVEHALASETGSILVFLPGQAEIRRVQEQLAERLDS--- 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 632 kirELIICPIYANLPSELQAKIFEPTPEGARKVVLATNIAETSLTIDGIKYVVDPGFSKMKSYNPRTGMESLLITPISKA 711
Cdd:TIGR01970 236 ---DVLICPLYGELSLAAQDRAIKPDPQGRRKVVLATNIAETSLTIEGIRVVIDSGLARVARFDPKTGITRLETVRISQA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 712 SATQRAGRAGRTSPGKCYRLYTAFNYNNdLEENTVPEVQRTNLASVVLALKSLGIHDLINFDFMDPPPAEALVKSLELLF 791
Cdd:TIGR01970 313 SATQRAGRAGRLEPGVCYRLWSEEQHQR-LPAQDEPEILQADLSGLALELAQWGAKDPSDLRWLDAPPSVALAAARQLLQ 391
|
410 420 430
....*....|....*....|....*....|..
gi 334182986 792 ALGALNKLGELTKAGRRMAEFPLDPMLSKMIV 823
Cdd:TIGR01970 392 RLGALDAQGRLTAHGKAMAALGCHPRLAAMLL 423
|
|
| PRK11664 |
PRK11664 |
ATP-dependent RNA helicase HrpB; Provisional |
393-841 |
1.55e-101 |
|
ATP-dependent RNA helicase HrpB; Provisional
Pssm-ID: 236950 [Multi-domain] Cd Length: 812 Bit Score: 337.67 E-value: 1.55e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 393 SLPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIP-QYLHEAGYTkrGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEV 471
Cdd:PRK11664 3 SLPVAAVLPELLTALKTAPQVLLKAPTGAGKSTWLPlQLLQHGGIN--GKIIMLEPRRLAARNVAQRLAEQLGEKPGETV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 472 GYSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDI-ARFRPDLKLLISSATMD 550
Cdd:PRK11664 81 GYRMRAESKVGPNTRLEVVTEGILTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVqQGLRDDLKLLIMSATLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 551 AEKFSDYFDTAPIFSFPGRRYPVEINYTSAPEADYMDAAIVTILTIHVREPLGDILVFFTGQEEIETAEEILKHRIRglg 630
Cdd:PRK11664 161 NDRLQQLLPDAPVIVSEGRSFPVERRYQPLPAHQRFDEAVARATAELLRQESGSLLLFLPGVGEIQRVQEQLASRVA--- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 631 tkiRELIICPIYANLPSELQAKIFEPTPEGARKVVLATNIAETSLTIDGIKYVVDPGFSKMKSYNPRTGMESLLITPISK 710
Cdd:PRK11664 238 ---SDVLLCPLYGALSLAEQQKAILPAPAGRRKVVLATNIAETSLTIEGIRLVVDSGLERVARFDPKTGLTRLVTQRISQ 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 711 ASATQRAGRAGRTSPGKCYRLYTAFNYNNDLEENTvPEVQRTNLASVVLALKSLGIHDLINFDFMDPPPAEALVKSLELL 790
Cdd:PRK11664 315 ASMTQRAGRAGRLEPGICLHLYSKEQAERAAAQSE-PEILHSDLSGLLLELLQWGCHDPAQLSWLDQPPAAALAAAKRLL 393
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 334182986 791 FALGALNKLGELTKAGRRMAEFPLDPMLSKMIVVSDKYkcSDEIISIAAML 841
Cdd:PRK11664 394 QQLGALDGQGRLTARGRKMAALGNDPRLAAMLVAAKED--DEAALATAAKL 442
|
|
| DEXHc_DHX8 |
cd17971 |
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as ... |
389-567 |
5.46e-96 |
|
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22) acts late in the splicing of pre-mRNA and mediates the release of the spliced mRNA from spliceosomes. DHX8 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350729 [Multi-domain] Cd Length: 179 Bit Score: 301.32 E-value: 5.46e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 389 EVRRSLPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLG 468
Cdd:cd17971 1 EQRESLPIYKLKEQLIQAVHDNQILVVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVAEEFGCCLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 469 HEVGYSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSAT 548
Cdd:cd17971 81 QEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLSQYSVIMLDEAHERTIHTDVLFGLLKKTVQKRPDLKLIVTSAT 160
|
170
....*....|....*....
gi 334182986 549 MDAEKFSDYFDTAPIFSFP 567
Cdd:cd17971 161 LDAVKFSQYFYEAPIFTIP 179
|
|
| DEXHc_RHA-like |
cd17917 |
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ... |
410-565 |
4.65e-93 |
|
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438707 [Multi-domain] Cd Length: 159 Bit Score: 292.44 E-value: 4.65e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 410 HQVLVIVGDTGSGKTTQIPQYLHEAGYTK--RGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVGYSIRFEDCTSDKTVL 487
Cdd:cd17917 1 NQVVVIVGETGSGKTTQVPQFLLEDGLAKggKGRIVCTQPRRIAAISVAERVAEERGEKLGEEVGYQIRFESKTSSKTRI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 334182986 488 KYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATMDAEKFSDYFDTAPIFS 565
Cdd:cd17917 81 KFCTDGILLRELLSDPLLSGYSHVILDEAHERSLDTDFLLGLLKDLLRKRPDLKVILMSATLDAEKFSSYFGGAPVIH 158
|
|
| DEXHc_DHX38 |
cd17983 |
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as ... |
394-565 |
8.06e-90 |
|
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as PRP16) is involved in pre-mRNA splicing. DHX38 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350741 [Multi-domain] Cd Length: 173 Bit Score: 284.74 E-value: 8.06e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVGY 473
Cdd:cd17983 1 LPIFAVRQELLNVIRDNNVVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGVELGEEVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 474 SIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATMDAEK 553
Cdd:cd17983 81 AIRFEDCTSENTVIKYMTDGILLRESLRDPDLDKYSAIIMDEAHERSLNTDVLFGLLREVVARRRDLKLIVTSATMDADK 160
|
170
....*....|..
gi 334182986 554 FSDYFDTAPIFS 565
Cdd:cd17983 161 FADFFGNVPIFT 172
|
|
| DEXHc_DHX15 |
cd17973 |
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ... |
386-565 |
5.47e-89 |
|
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438709 [Multi-domain] Cd Length: 187 Bit Score: 282.77 E-value: 5.47e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 386 ELQEVRRSLPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGK--VGCTQPRRVAAMSVAARVAQEM 463
Cdd:cd17973 5 EILEKRRELPVWEQKEDFLKLLKNNQILVLVGETGSGKTTQIPQFVLDDELPHQPKklVACTQPRRVAAMSVAQRVAEEM 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 464 GVKLGHEVGYSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLL 543
Cdd:cd17973 85 DVKLGEEVGYSIRFEDCSSAKTILKYMTDGMLLREAMSDPLLSRYSVIILDEAHERTLATDILMGLLKEVVRRRPDLKLI 164
|
170 180
....*....|....*....|..
gi 334182986 544 ISSATMDAEKFSDYFDTAPIFS 565
Cdd:cd17973 165 VMSATLDAGKFQKYFDNAPLLK 186
|
|
| DEXHc_DHX33 |
cd17978 |
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ... |
394-564 |
6.16e-88 |
|
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438710 [Multi-domain] Cd Length: 178 Bit Score: 279.62 E-value: 6.16e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVGY 473
Cdd:cd17978 1 LPIYSARKRLLEELRKHDTVIIIGETGSGKTTQIPQYLYEAGFARGGMIGITQPRRVAAVSVAKRVAEEMGVELGQLVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 474 SIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFR-----PDLKLLISSAT 548
Cdd:cd17978 81 SVRFDDVTSEETRIKYMTDGMLLREAIGDPLLSKYSVIILDEAHERTVHTDVLFGLVKSAQRRRkeqklSPLKVIIMSAT 160
|
170
....*....|....*.
gi 334182986 549 MDAEKFSDYFDTAPIF 564
Cdd:cd17978 161 LDADLFSEYFNGAPVL 176
|
|
| DEXHc_DHX35 |
cd17980 |
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and ... |
394-560 |
1.59e-80 |
|
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and seems to be associated with risk to thyroid cancers. It also has been shown to positively regulate poxviruses, such as Myxoma virus. DEAH-box helicase 35 (DHX35) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350738 [Multi-domain] Cd Length: 185 Bit Score: 260.09 E-value: 1.59e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGK-VGCTQPRRVAAMSVAARVAQEMGVKLGHEVG 472
Cdd:cd17980 1 LPVFKLRNHILYLVENYQTIVIVGETGCGKSTQIPQYLAEAGWTAGGRvVGCTQPRRVAAVTVAGRVAEEMGAVLGHEVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 473 YSIRFEDCTSD-KTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATMDA 551
Cdd:cd17980 81 YCIRFDDCTDPqATRIKFLTDGMLVREMMLDPLLTKYSVIMLDEAHERTLYTDILIGLLKKIQKKRGDLRLIVASATLDA 160
|
....*....
gi 334182986 552 EKFSDYFDT 560
Cdd:cd17980 161 EKFRDFFNQ 169
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
571-732 |
2.16e-77 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 250.91 E-value: 2.16e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 571 YPVEINYTSAP-----------EADYMDAAIVTILTIHVREPLGDILVFFTGQEEIETAEEILKHRIRGLGTKirELIIC 639
Cdd:cd18791 1 FPVEVYYLEDIlellgissekeDPDYVDAAVRLILQIHRTEEPGDILVFLPGQEEIERLCELLREELLSPDLG--KLLVL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 640 PIYANLPSELQAKIFEPTPEGARKVVLATNIAETSLTIDGIKYVVDPGFSKMKSYNPRTGMESLLITPISKASATQRAGR 719
Cdd:cd18791 79 PLHSSLPPEEQQRVFEPPPPGVRKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISKASAEQRAGR 158
|
170
....*....|...
gi 334182986 720 AGRTSPGKCYRLY 732
Cdd:cd18791 159 AGRTRPGKCYRLY 171
|
|
| DEXHc_DHX40 |
cd17984 |
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ... |
394-565 |
7.66e-71 |
|
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350742 [Multi-domain] Cd Length: 178 Bit Score: 233.21 E-value: 7.66e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVGY 473
Cdd:cd17984 1 LPIQKQRKKLVQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRRVAAISVAQRVAEEMKCTLGSKVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 474 SIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDI-----ARFRPDLKLLISSAT 548
Cdd:cd17984 81 QVRFDDCSSKETAIKYMTDGCLLRHILADPNLTKYSVIILDEAHERSLTTDILFGLLKKLfqeksPNRKEHLKVVVMSAT 160
|
170
....*....|....*..
gi 334182986 549 MDAEKFSDYFDTAPIFS 565
Cdd:cd17984 161 LELAKLSAFFGNCPVFD 177
|
|
| DEXHc_HrpA |
cd17989 |
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ... |
394-563 |
1.15e-63 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350747 [Multi-domain] Cd Length: 173 Bit Score: 213.09 E-value: 1.15e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVGY 473
Cdd:cd17989 1 LPVSQKRDEIAKAIAENQVVIIAGETGSGKTTQLPKICLELGRGIRGLIGHTQPRRLAARSVAERIAEELKTELGGAVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 474 SIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATMDAEK 553
Cdd:cd17989 81 KVRFTDQTSDETCVKLMTDGILLAETQTDRYLRAYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATIDAER 160
|
170
....*....|
gi 334182986 554 FSDYFDTAPI 563
Cdd:cd17989 161 FSRHFNNAPI 170
|
|
| DEXHc_DHX37 |
cd17982 |
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ... |
394-556 |
3.78e-59 |
|
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350740 [Multi-domain] Cd Length: 191 Bit Score: 201.04 E-value: 3.78e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKR-----GKVGCTQPRRVAAMSVAARVAQEMGVkLG 468
Cdd:cd17982 1 LPILAEEQEIMEAINENPVVIICGETGSGKTTQVPQFLYEAGFGSPesdnpGMIGITQPRRVAAVSMAKRVAEELNV-FG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 469 HEVGYSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPD--------- 539
Cdd:cd17982 80 KEVSYQIRYDSTVSENTKIKFMTDGVLLKEIQTDFLLRKYSVIIIDEAHERSVNTDILIGMLSRIVPLRAKlylqdqtvk 159
|
170
....*....|....*...
gi 334182986 540 -LKLLISSATMDAEKFSD 556
Cdd:cd17982 160 pLKLVIMSATLRVEDFTE 177
|
|
| DEXHc_DHX34 |
cd17979 |
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in ... |
394-563 |
7.53e-58 |
|
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in the nonsense-mediated decay (NMD), a surveillance mechanism that degrades aberrant mRNAs. DHX34 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350737 [Multi-domain] Cd Length: 170 Bit Score: 196.51 E-value: 7.53e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKrgkVGCTQPRRVAAMSVAARVAQEMGVKLGHEVGY 473
Cdd:cd17979 1 LPIAQYREKIIELLKTHQVVIVAGDTGCGKSTQVPQYLLAAGFRH---IACTQPRRIACISLAKRVAFESLNQYGSKVAY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 474 SIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATMDAEK 553
Cdd:cd17979 78 QIRFERTRTLATKLLFLTEGLLLRQIQRDASLPQYNVLILDEVHERHLHGDFLLGVLRCLLRLRPDLKLILMSATINIEL 157
|
170
....*....|
gi 334182986 554 FSDYFDTAPI 563
Cdd:cd17979 158 FSGYFEGAPV 167
|
|
| DEXHc_DHX36 |
cd17981 |
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as ... |
394-564 |
2.23e-54 |
|
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as G4-resolvase 1 or G4R1, MLE-like protein 1 and RNA helicase associated with AU-rich element or RHAU) unwinds a G4-quadruplex in human telomerase RNA. DHX36 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350739 [Multi-domain] Cd Length: 180 Bit Score: 186.97 E-value: 2.23e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEaGYTKRGK-----VGCTQPRRVAAMSVAARVAQEMG--VK 466
Cdd:cd17981 1 LPSYGMKQEIINMIDNNQVTVISGETGCGKTTQVTQFILD-DAIERGKgsscrIVCTQPRRISAISVAERVAAERAesCG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 467 LGHEVGYSIRFEDCTSDKTV-LKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLIS 545
Cdd:cd17981 80 LGNSTGYQIRLESRKPRKQGsILYCTTGIVLQWLQSDPHLSNVSHLVLDEIHERNLQSDVLMGIVKDLLPFRSDLKVILM 159
|
170
....*....|....*....
gi 334182986 546 SATMDAEKFSDYFDTAPIF 564
Cdd:cd17981 160 SATLNAEKFSDYFNNCPMI 178
|
|
| DEXHc_DHX57 |
cd17985 |
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the ... |
394-563 |
2.25e-52 |
|
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350743 [Multi-domain] Cd Length: 177 Bit Score: 181.19 E-value: 2.25e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEA----GYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGH 469
Cdd:cd17985 1 LPAWQERETILELLEKHQVLVISGMTGCGKTTQIPQFILDNslqgPPLPVANIICTQPRRISAISVAERVAQERAERVGQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 470 EVGYSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATM 549
Cdd:cd17985 81 SVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDPTLQGVTHVIVDEVHERTEESDFLLLVLKDLMVQRPDLKVILMSATL 160
|
170
....*....|....
gi 334182986 550 DAEKFSDYFDTAPI 563
Cdd:cd17985 161 NAELFSDYFNSCPV 174
|
|
| DEXHc_DHX32 |
cd17977 |
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the ... |
394-563 |
9.16e-51 |
|
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350735 [Multi-domain] Cd Length: 176 Bit Score: 176.55 E-value: 9.16e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHE---AGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHE 470
Cdd:cd17977 1 LPVWEAKYEFMESLAHNQIVIVSGDAKTGKSSQIPQWCAEyclSAHYQHGVVVCTQVHKQTAVWLALRVADEMDVNIGHE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 471 VGYSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATMD 550
Cdd:cd17977 81 VGYVIPFENCCTNETILRYCTDDMLLREMMSDPLLESYGVIILDDAHERTVSTDVLLGLLKDVLLSRPELKLVIITCPHL 160
|
170
....*....|...
gi 334182986 551 AEKFSDYFDTAPI 563
Cdd:cd17977 161 SSKLLSYYGNVPL 173
|
|
| DEXHc_DHX29 |
cd17975 |
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of ... |
394-565 |
6.06e-50 |
|
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of the 43S pre-initiation complex involved in translation initiation of mRNAs with structured 5'-UTRs. DHX29 is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350733 [Multi-domain] Cd Length: 183 Bit Score: 174.72 E-value: 6.06e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHE-----AGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLG 468
Cdd:cd17975 1 LPVFKHRESILETLKRHRVVVVAGETGSGKSTQVPQFLLEdlllnGGTAQKCNIVCTQPRRISAMSLATRVCEELGCESG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 469 -----HEVGYSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLL 543
Cdd:cd17975 81 pggknSLCGYQIRMESRTGEATRLLYCTTGVLLRKLQEDGLLSSISHIIVDEVHERSVQSDFLLIILKEILHKRSDLHLI 160
|
170 180
....*....|....*....|..
gi 334182986 544 ISSATMDAEKFSDYFDTAPIFS 565
Cdd:cd17975 161 LMSATVDCEKFSSYFTHCPILR 182
|
|
| DEXHc_HrpB |
cd17990 |
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ... |
394-565 |
1.17e-49 |
|
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438711 [Multi-domain] Cd Length: 174 Bit Score: 173.29 E-value: 1.17e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVGY 473
Cdd:cd17990 1 LPIAAVLPALRAALDAGGQVVLEAPPGAGKTTRVPLALLAELWIAGGKIIVLEPRRVAARAAARRLATLLGEAPGETVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 474 SIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIAR-FRPDLKLLISSATMDAE 552
Cdd:cd17990 81 RVRGESRVGRRTRVEVVTEGVLLRRLQRDPELSGVGAVILDEFHERSLDADLALALLLEVQQlLRDDLRLLAMSATLDGD 160
|
170
....*....|...
gi 334182986 553 KFSDYFDTAPIFS 565
Cdd:cd17990 161 GLAALLPEAPVVE 173
|
|
| DEXHc_YTHDC2 |
cd17987 |
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) ... |
394-563 |
4.76e-49 |
|
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) regulates mRNA translation and stability via binding to N6-methyladenosine, a modified RNA nucleotide enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. YTHDC2 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350745 [Multi-domain] Cd Length: 176 Bit Score: 171.94 E-value: 4.76e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRG--KVGCTQPRRVAAMSVAARVAQEMGVKLGHEV 471
Cdd:cd17987 1 LPVFEKQEQIVRIIKENKVVLIVGETGSGKTTQIPQFLLDDCYANGIpcRIFCTQPRRLAAIAVAERVAAERGEKIGQTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 472 GYSIRFEDCTSDKTVLKYMTDGMLLRELL-GEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATMD 550
Cdd:cd17987 81 GYQIRLESRVSPKTLLTFCTNGVLLRTLMaGDSALSTVTHVIVDEVHERDRFSDFLLTKLRDILQKHPNLKLILSSAALD 160
|
170
....*....|...
gi 334182986 551 AEKFSDYFDTAPI 563
Cdd:cd17987 161 VNLFIRYFGSCPV 173
|
|
| DEXHc_DHX30 |
cd17976 |
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an ... |
394-563 |
1.01e-48 |
|
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an important role in the assembly of the mitochondrial large ribosomal subunit. DHX30 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350734 [Multi-domain] Cd Length: 178 Bit Score: 170.74 E-value: 1.01e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGC----TQPRRVAAMSVAARVAQEMGVKLGH 469
Cdd:cd17976 1 LPVDSHKESILSAIEQNPVVVISGDTGCGKTTRIPQFILEDYVLRGRGARCnvviTQPRRISAVSVAQRVAHELGPNLRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 470 EVGYSIRFEDCTSDKT-VLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSAT 548
Cdd:cd17976 81 NVGYQVRLESRPPPRGgALLFCTVGVLLKKLQSNPRLEGVSHVIVDEVHERDVNTDFLLILLKGVLQLNPELRVVLMSAT 160
|
170
....*....|....*
gi 334182986 549 MDAEKFSDYFDTAPI 563
Cdd:cd17976 161 GDNQRLSRYFGGCPV 175
|
|
| DEXQc_DQX1 |
cd17986 |
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 ... |
394-563 |
1.47e-44 |
|
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 (DQX1) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350744 [Multi-domain] Cd Length: 177 Bit Score: 158.91 E-value: 1.47e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIV-GDTGSGKTTQIPQYLHEAGYTKR---GKVGCTQPRRVAAMSVAARVAQEMGVKLGH 469
Cdd:cd17986 1 LPIWAAKFTFLEQLESPSGIVLVsGEPGSGKSTQVPQWCAEFALSRGfqkGQVTVTQPHPLAARSLALRVADEMDLNLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 470 EVGYSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATM 549
Cdd:cd17986 81 EVGYSIPQEDCTGPNTILRFCWDRLLLQEMTSTPLLGAWGVVVLDEAQERSVASDSLLGLLKDVRLQRPELRVVVVTSPA 160
|
170
....*....|....
gi 334182986 550 DAEKFSDYFDTAPI 563
Cdd:cd17986 161 LEPKLRAFWGNPPV 174
|
|
| DEXHc_DHX9 |
cd17972 |
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ... |
355-563 |
1.04e-42 |
|
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ATP-dependent RNA helicase A or RHA and leukophysin or LKP) plays an important role in many cellular processes, including regulation of DNA replication, transcription, translation, microRNA biogenesis, RNA processing and transport, and maintenance of genomic stability. DHX9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350730 [Multi-domain] Cd Length: 234 Bit Score: 155.76 E-value: 1.04e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 355 IKESVMAGENYED-AMDAKQKSQD-LAEKTALEELQEVRRSLPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLH 432
Cdd:cd17972 18 IDEGPLAFATPEQiSMDLKNELMYqREQDHNLQQILQERELLPVKKFREEILEAISNNPVVIIRGATGCGKTTQVPQYIL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 433 EAgYTKRGKVG-----CTQPRRVAAMSVAARVAQEMGVKLGHEVGYSIRFEDCT-SDKTVLKYMTDGMLLRELlgEPDLA 506
Cdd:cd17972 98 DD-FIQNDRAAecnivVTQPRRISAVSVAERVAFERGEEVGKSCGYSVRFESVLpRPHASILFCTVGVLLRKL--EAGIR 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 334182986 507 SYSVVIVDEAHERTLSTDILFGLVKDIARFRPDLKLLISSATMDAEKFSDYFDTAPI 563
Cdd:cd17972 175 GISHVIVDEIHERDINTDFLLVVLRDVVQAYPDLRVILMSATIDTSMFCEYFFNCPV 231
|
|
| DEXHc_TDRD9 |
cd17988 |
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also ... |
394-564 |
3.61e-39 |
|
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also known as HIG-1or NET54 or C14orf75) is a part of the nuclear PIWI-interacting RNA (piRNA) pathway essential for transposon silencing and male fertility TDRD9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350746 [Multi-domain] Cd Length: 180 Bit Score: 143.80 E-value: 3.61e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 394 LPIYTYRDQLLKAVEEHQVLVIVGDTGSGKTTQIPQYLHEAgYTKRGK---VGCTQPRRVAAMSVAARVAQEMGVKLGHE 470
Cdd:cd17988 1 LPIYAKREEILSLIEANSVVIIKGATGCGKTTQLPQFILDH-YYKRGKycnIVVTQPRRIAAISIARRVSQEREWTLGSL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 471 VGYSIRFEDCTSDKTVLKYMTDGMLLRELLGEPDLASYSVVIVDEAHERTLSTDILFGLVKDIARFRPD-LKLLISSATM 549
Cdd:cd17988 80 VGYQVGLERPASEETRLIYCTTGVLLQKLINNKTLTEYTHIILDEVHERDQELDFLLLVVRRLLRTNSRhVKIILMSATI 159
|
170
....*....|....*....
gi 334182986 550 DAEKFSDYFDT----APIF 564
Cdd:cd17988 160 SCKEFADYFTTpnnpAYVF 178
|
|
| HA2 |
smart00847 |
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino ... |
792-877 |
1.55e-27 |
|
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 214852 [Multi-domain] Cd Length: 82 Bit Score: 106.58 E-value: 1.55e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 792 ALGALNKLGELTKAGRRMAEFPLDPMLSKMIVVSDKYKCSDEIISIAAMLSIGGsifYRPKDKQVHADNARMNFHTGNvG 871
Cdd:smart00847 1 ELGALDDDGRLTPLGRKMAELPLDPRLAKMLLAAAEFGCLDEILTIVAMLSVGD---PRPKEKREDADAARRRFADPE-S 76
|
....*.
gi 334182986 872 DHIALL 877
Cdd:smart00847 77 DHLTLL 82
|
|
| HA2 |
pfam04408 |
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in ... |
786-876 |
5.78e-27 |
|
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 461295 [Multi-domain] Cd Length: 104 Bit Score: 105.78 E-value: 5.78e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 786 SLELLFALGALNKLGELTKAGRRMAEFPLDPMLSKMIVVSDKYKCSDEIISIAAMLSiGGSIFYRP---------KDKQV 856
Cdd:pfam04408 1 ALELLYYLGALDEDGELTPLGRKMAELPLDPRLAKMLLAAAELGCLDEVLTIVAALS-VRDPFVQPnfldprsaaKAARR 79
|
90 100
....*....|....*....|....*
gi 334182986 857 HADNA-----RMNFHTGNVGDHIAL 876
Cdd:pfam04408 80 RRRAAdekarAKFARLDLEGDHLTL 104
|
|
| OB_NTP_bind |
pfam07717 |
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus ... |
934-1011 |
3.55e-26 |
|
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus of the DEAD-box helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. There do seem to be a couple of instances where it occurs by itself -. The structure PDB:3i4u adopts an OB-fold. helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. This C-terminal domain of the yeast helicase contains an oligonucleotide/oligosaccharide-binding (OB)-fold which seems to be placed at the entrance of the putative nucleic acid cavity. It also constitutes the binding site for the G-patch-containing domain of Pfa1p. When found on DEAH/RHA helicases, this domain is central to the regulation of the helicase activity through its binding of both RNA and G-patch domain proteins.
Pssm-ID: 400182 [Multi-domain] Cd Length: 82 Bit Score: 102.72 E-value: 3.55e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 934 VRKSIVAGFFPHTAKL-QKNGSYRTVKHPQTVHIHPNSGLSQVL---PRWVVYHELVLTSKEYMRQVTELKPEWLIELAP 1009
Cdd:pfam07717 1 LRAALAAGLYPNVARRdPKGKGYTTLSDNQRVFIHPSSVLFNEKtfpPEWVVYQELVETTKVYIRTVTAISPEWLLLFAP 80
|
..
gi 334182986 1010 HY 1011
Cdd:pfam07717 81 HI 82
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
405-564 |
8.00e-26 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 106.04 E-value: 8.00e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 405 KAVEEHQVLVIVGDTGSGKTTQIPQYLHEAGY-TKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVGY------SIRF 477
Cdd:smart00487 19 ALLSGLRDVILAAPTGSGKTLAALLPALEALKrGKGGRVLVLVPTRELAEQWAEELKKLGPSLGLKVVGLyggdskREQL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 478 EDCTSDKTVLKYMTDGMLLRELL-GEPDLASYSVVIVDEAHERTLS--TDILFGLVKdiaRFRPDLKLLISSATM--DAE 552
Cdd:smart00487 99 RKLESGKTDILVTTPGRLLDLLEnDKLSLSNVDLVILDEAHRLLDGgfGDQLEKLLK---LLPKNVQLLLLSATPpeEIE 175
|
170
....*....|..
gi 334182986 553 KFSDYFDTAPIF 564
Cdd:smart00487 176 NLLELFLNDPVF 187
|
|
| HELICc |
smart00490 |
helicase superfamily c-terminal domain; |
620-722 |
9.74e-14 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 67.24 E-value: 9.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 620 EILKHRIRGLGTKIreliiCPIYANLPSELQAKIFEPTPEGARKVVLATNIAETSLTIDGIKYVVDPGFskmksynprtg 699
Cdd:smart00490 1 EELAELLKELGIKV-----ARLHGGLSQEEREEILDKFNNGKIKVLVATDVAERGLDLPGVDLVIIYDL----------- 64
|
90 100
....*....|....*....|...
gi 334182986 700 mesllitPISKASATQRAGRAGR 722
Cdd:smart00490 65 -------PWSPASYIQRIGRAGR 80
|
|
| PHA02653 |
PHA02653 |
RNA helicase NPH-II; Provisional |
392-741 |
5.38e-13 |
|
RNA helicase NPH-II; Provisional
Pssm-ID: 177443 [Multi-domain] Cd Length: 675 Bit Score: 73.09 E-value: 5.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 392 RSLPIYTYRdQLLKAVEEHQVLVIVGDTGSGKTTQIPQ------YLHeAGYTKRGKVGCTQPRRVAAMSVAaRVAQemgV 465
Cdd:PHA02653 162 ASLQPDVQL-KIFEAWISRKPVVLTGGTGVGKTSQVPKlllwfnYLF-GGFDNLDKIDPNFIERPIVLSLP-RVAL---V 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 466 KLgHEVGY--SIRFEDCTSDKTVLKY--MTD----------GMLL---RELLGEpdLASYSVVIVDEAHERTLSTDILFG 528
Cdd:PHA02653 236 RL-HSITLlkSLGFDEIDGSPISLKYgsIPDelintnpkpyGLVFsthKLTLNK--LFDYGTVIIDEVHEHDQIGDIIIA 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 529 LV-KDIARFRpdlKLLISSATM--DAEKFSDYFDTAPIFSFPG-RRYP---VEINYTSAPEADYMDAA-----IVTILTI 596
Cdd:PHA02653 313 VArKHIDKIR---SLFLMTATLedDRDRIKEFFPNPAFVHIPGgTLFPiseVYVKNKYNPKNKRAYIEeekknIVTALKK 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 597 HVREPLGDILVFFTGQEEIETAEEILKHRIRGLGTKIreliicpIYANLPS--ELQAKIFeptpegARK---VVLATNIA 671
Cdd:PHA02653 390 YTPPKGSSGIVFVASVSQCEEYKKYLEKRLPIYDFYI-------IHGKVPNidEILEKVY------SSKnpsIIISTPYL 456
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334182986 672 ETSLTIDGIKYVVDPGfskmKSYNPR--TGMESLlitpISKASATQRAGRAGRTSPGkcyrLYTAFnYNNDL 741
Cdd:PHA02653 457 ESSVTIRNATHVYDTG----RVYVPEpfGGKEMF----ISKSMRTQRKGRVGRVSPG----TYVYF-YDLDL 515
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
590-722 |
3.01e-11 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 61.07 E-value: 3.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 590 IVTILTIHVREPLGDILVFFTGQEEIEtaEEILKHRirglgtkiRELIICPIYANLPSELQAKIFEPTPEGARKVVLATN 669
Cdd:pfam00271 3 LEALLELLKKERGGKVLIFSQTKKTLE--AELLLEK--------EGIKVARLHGDLSQEEREEILEDFRKGKIDVLVATD 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 334182986 670 IAETSLTIDGIKYVVDpgfskmksYNPRTGMESLLitpiskasatQRAGRAGR 722
Cdd:pfam00271 73 VAERGLDLPDVDLVIN--------YDLPWNPASYI----------QRIGRAGR 107
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
413-548 |
2.00e-09 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 57.03 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 413 LVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQE--MGVKLG---HEVGYSIRFEDCTSDKTVL 487
Cdd:cd00046 4 VLITAPTGSGKTLAALLAALLLLLKKGKKVLVLVPTKALALQTAERLRELfgPGIRVAvlvGGSSAEEREKNKLGDADII 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334182986 488 kYMTDGMLLRELLGE--PDLASYSVVIVDEAHERTLSTD-ILFGLVKDIARFRPDLKLLISSAT 548
Cdd:cd00046 84 -IATPDMLLNLLLREdrLFLKDLKLIIVDEAHALLIDSRgALILDLAVRKAGLKNAQVILLSAT 146
|
|
| DEXHc_viral_Ns3 |
cd17931 |
DEXH-box helicase domain of NS3 protease-helicase; NS3 is a nonstructural multifunctional ... |
411-517 |
4.06e-07 |
|
DEXH-box helicase domain of NS3 protease-helicase; NS3 is a nonstructural multifunctional protein found in pestiviruses that contains an N-terminal protease and a C-terminal helicase. The N-terminal domain is a chymotrypsin-like serine protease, which is responsible for most of the maturation cleavages of the polyprotein precursor in the cytosolic side of the endoplasmic reticulum membrane. The C-terminal domain, about two-thirds of NS3, is a helicase belonging to superfamily 2 (SF2) thought to be important for unwinding highly structured regions of the RNA genome during replication. NS3 plays an essential role in viral polyprotein processing and genome replication. NS3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350689 [Multi-domain] Cd Length: 151 Bit Score: 50.63 E-value: 4.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 411 QVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQEmgvklghEVGYSI-RFEDCTSDKTVLKY 489
Cdd:cd17931 2 QLTVLDLHPGAGKTTRVLPQIIREAIKKRLRTLVLAPTRVVAAEMYEALRGL-------PIRYRTgAVKEEHGGNEIVDY 74
|
90 100
....*....|....*....|....*...
gi 334182986 490 MTDGMLLRELLGEPDLASYSVVIVDEAH 517
Cdd:cd17931 75 MCHGTFTCRLLSPKRVPNYNLIIMDEAH 102
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
399-552 |
9.53e-06 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 46.85 E-value: 9.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 399 YRDQL--LKAVEEHQVLVIVGDTGSGKTT--QIPqYLHEAGYTKRGKVG-CTQPRRVAA---MSVAARVAQEMGVKLGHE 470
Cdd:pfam00270 1 TPIQAeaIPAILEGRDVLVQAPTGSGKTLafLLP-ALEALDKLDNGPQAlVLAPTRELAeqiYEELKKLGKGLGLKVASL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 471 VGYSIRFEDCTSDKTV-LKYMTDGMLLRELLGEPDLASYSVVIVDEAHErtlSTDILFG--LVKDIARFRPDLKLLISSA 547
Cdd:pfam00270 80 LGGDSRKEQLEKLKGPdILVGTPGRLLDLLQERKLLKNLKLLVLDEAHR---LLDMGFGpdLEEILRRLPKKRQILLLSA 156
|
....*
gi 334182986 548 TMDAE 552
Cdd:pfam00270 157 TLPRN 161
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
112-414 |
2.11e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.98 E-value: 2.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 112 KSSVSESRKSDKGKKRFRKKSgQSDESDGEVAVREDSRHVRRKVSEEDDGSESEEERVRDQKEREELEQHLKDRDTARTR 191
Cdd:PTZ00121 1450 KKKAEEAKKAEEAKKKAEEAK-KADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK 1528
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 192 KLTEqtlskKEKEEAVRRANALEKDDlyslrKVSRQEYLKKREQ-KKLDELRDEIEDEQY-LFGGEKLTETELREFRYKK 269
Cdd:PTZ00121 1529 KAEE-----AKKADEAKKAEEKKKAD-----ELKKAEELKKAEEkKKAEEAKKAEEDKNMaLRKAEEAKKAEEARIEEVM 1598
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 270 ELYDLVKK------RTQDEDNVEEGGVDQEKRFSVAVQRYRDLDSTEKMNPFAEQEAWEDHQIGKATLKFGA-KNKQASD 342
Cdd:PTZ00121 1599 KLYEEEKKmkaeeaKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAeEDKKKAE 1678
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334182986 343 DYQFVFEDQinfikesvmagENYEDAMDAKQKSQDLAEKTALEELQEVRRSlpiytyrDQLLKAVEEHQVLV 414
Cdd:PTZ00121 1679 EAKKAEEDE-----------KKAAEALKKEAEEAKKAEELKKKEAEEKKKA-------EELKKAEEENKIKA 1732
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
112-389 |
2.31e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.60 E-value: 2.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 112 KSSVSESRKSDKGKKRFRKKSGQSDESDGEVAVREDSRHVRR--KVSEEDDGSESEEERVRDQ-------KEREELEQHL 182
Cdd:PTZ00121 1476 KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKaeEAKKADEAKKAEEAKKADEakkaeekKKADELKKAE 1555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 183 KDRDTARTRKLTEQTLSKKEKEEAVRRANALEKDD---------LYSLRKVSRQEYLKKREQKKL--DELRDEIEDEQYL 251
Cdd:PTZ00121 1556 ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEearieevmkLYEEEKKMKAEEAKKAEEAKIkaEELKKAEEEKKKV 1635
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 252 FGGEKLTETELR---EFRYKKELY-----DLVKKRTQDEDNVEEGGVDQEKRFSVAVQRYRDLDSTEKMNPFAEQEAWEd 323
Cdd:PTZ00121 1636 EQLKKKEAEEKKkaeELKKAEEENkikaaEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEE- 1714
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 334182986 324 hqigkatlkfgakNKQASddyQFVFEDQINFIKESVMAGENYEDAMDAKQKSQDLAEKTALEELQE 389
Cdd:PTZ00121 1715 -------------KKKAE---ELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKK 1764
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
411-526 |
5.84e-05 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 43.87 E-value: 5.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 411 QVLVIVGDTGSGKTTQIPQYLHEAGYTKRGKVGCTQPRRVAAMSVAARVAQEMGVKLGHEVgysiRFEDCTSdktvlkym 490
Cdd:pfam13401 6 GILVLTGESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSGTSPKDLLRALLRALGLPLSGRL----SKEELLA-------- 73
|
90 100 110
....*....|....*....|....*....|....*.
gi 334182986 491 tdgMLLRELLgepDLASYSVVIVDEAHErtLSTDIL 526
Cdd:pfam13401 74 ---ALQQLLL---ALAVAVVLIIDEAQH--LSLEAL 101
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
112-381 |
7.93e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.06 E-value: 7.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 112 KSSVSESRKSDKGKKR---FRKKSGQSDESDGEVAVREDSRHVRR---KVSEEDDGSESEEERVRDQKEREELEQHLKDR 185
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKveqLKKKEAEEKKKAEELKKAEEENKIKAaeeAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 186 DTARTrklTEQtLSKKEKEEaVRRANALEKDDLYSLRKVSRQEYLKKREQKKLDELRDEIEDEQYLFGGEKLTETELREF 265
Cdd:PTZ00121 1699 EEAKK---AEE-LKKKEAEE-KKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 266 RYKKEL-------------YDLVKKRTQD----EDNVEEGG------VDQEKRFSVAVQRYRDLDSTEKMNpfaEQEAWE 322
Cdd:PTZ00121 1774 RKEKEAvieeeldeedekrRMEVDKKIKDifdnFANIIEGGkegnlvINDSKEMEDSAIKEVADSKNMQLE---EADAFE 1850
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 323 DHQIGKATLKFGAKNKQA-SDDYQFVFEDQINFIKESVMAGENYEDAMDAKQKSQDLAEK 381
Cdd:PTZ00121 1851 KHKFNKNNENGEDGNKEAdFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGK 1910
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
117-389 |
2.54e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.13 E-value: 2.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 117 ESRKSDKGKKRFRKKSGQSDESDGEVAVREDSRHVRRKvSEEDDGSESEEERVRDQKEREELEQHLKDRDTARTRKLTEQ 196
Cdd:PTZ00121 1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEA-KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAE 1610
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 197 TLSKKEKE----EAVRRANALEKDDLYSLRK----VSRQEYLKKREQ-----------------KKLDELRDEIEDEQyl 251
Cdd:PTZ00121 1611 EAKKAEEAkikaEELKKAEEEKKKVEQLKKKeaeeKKKAEELKKAEEenkikaaeeakkaeedkKKAEEAKKAEEDEK-- 1688
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 252 fggeKLTETELREFRYKKELYDLVKKRTQDEDNVEEGGVDQEKRFSVAVQRYRDLDSTEKMNPFAEQEAWEDHQIGKATL 331
Cdd:PTZ00121 1689 ----KAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKK 1764
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 334182986 332 KFGAKNKQASDDYQFVFEDQINfikesvmaGENYEDAMDAKQKSQDLaeKTALEELQE 389
Cdd:PTZ00121 1765 EEEKKAEEIRKEKEAVIEEELD--------EEDEKRRMEVDKKIKDI--FDNFANIIE 1812
|
|
| SF2_C |
cd18785 |
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases ... |
663-732 |
1.20e-03 |
|
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases include DEAD-box helicases, UvrB, RecG, Ski2, Sucrose Non-Fermenting (SNF) family helicases, and dicer proteins, among others. Similar to SF1 helicases, they do not form toroidal structures like SF3-6 helicases. SF2 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350172 [Multi-domain] Cd Length: 77 Bit Score: 38.45 E-value: 1.20e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334182986 663 KVVLATNIAETSLTIDGIKYVVDPGFskmksynprtgmesllitPISKASATQRAGRAGR--TSPGKCYRLY 732
Cdd:cd18785 24 EILVATNVLGEGIDVPSLDTVIFFDP------------------PSSAASYIQRVGRAGRggKDEGEVILFV 77
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
406-516 |
2.03e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 40.63 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 406 AVEEHQVLVIVGDTGSGKTT---QIPQYLHEAGYTKRGkvgctqprrvAAMSvaARVAQEMGVKLGHEVgysirfedcts 482
Cdd:pfam13604 14 LTSGDRVAVLVGPAGTGKTTalkALREAWEAAGYRVIG----------LAPT--GRAAKVLGEELGIPA----------- 70
|
90 100 110
....*....|....*....|....*....|....
gi 334182986 483 dktvlkyMTDGMLLRELLGEPDLASYSVVIVDEA 516
Cdd:pfam13604 71 -------DTIAKLLHRLGGRAGLDPGTLLIVDEA 97
|
|
| SF2_C_suv3 |
cd18805 |
C-terminal helicase domain of ATP-dependent RNA helicase; The SUV3 (suppressor of Var 3) gene ... |
603-722 |
3.10e-03 |
|
C-terminal helicase domain of ATP-dependent RNA helicase; The SUV3 (suppressor of Var 3) gene encodes a DNA and RNA helicase, which is localized in mitochondria and is a subunit of the degradosome complex involved in regulation of RNA surveillance and turnover. SUV3 exhibits DNA and RNA-dependent ATPase, DNA and RNA-binding and DNA and RNA unwinding activities. SUV3 is a DEAD-like helicase belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350192 [Multi-domain] Cd Length: 135 Bit Score: 39.08 E-value: 3.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 603 GDILVFFTGQEEIETAEEILKHrirglgTKIReliICPIYANLPSEL---QAKIFEpTPEGARKVVLATNIAETSLTIDg 679
Cdd:cd18805 19 GDCVVAFSRKDIFSLKREIEKR------TGLK---CAVIYGALPPETrrqQARLFN-DPESGYDVLVASDAIGMGLNLN- 87
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 334182986 680 IKYVVdpgFSKMKSYNprtGMEsllITPISKASATQRAGRAGR 722
Cdd:cd18805 88 IRRVI---FSSLSKFD---GNE---MRPLSPSEVKQIAGRAGR 121
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
56-392 |
9.11e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 40.12 E-value: 9.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 56 DTRSFAEEIFARVPRKTAGVNLYQKHEAEAamlVRKQKtyalldaddDEDEVVVEKKSSvsESRKSDKGKKRFRKKSGQS 135
Cdd:PTZ00121 1253 EIRKFEEARMAHFARRQAAIKAEEARKADE---LKKAE---------EKKKADEAKKAE--EKKKADEAKKKAEEAKKAD 1318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 136 DESDGEVAVREDSRHVRRKVSEEDDGSESEEERVRDQKEREELEQHLKDRDTARTRKLTEQTLSKKEKEEAVRRANALEK 215
Cdd:PTZ00121 1319 EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKK 1398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 216 DDLYSLRKVsrqEYLKKR--EQKKLDELRDEIEdeqylfggEKLTETELREFRYKKELYDLVKKRTQDEDNVEEGG--VD 291
Cdd:PTZ00121 1399 KAEEDKKKA---DELKKAaaAKKKADEAKKKAE--------EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkkAE 1467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 292 QEKRFSVAVQRYRDLDSTEKMNPFAEQEAWEDHQIGKAtlkfgAKNKQASDDYQFVFE----DQINFIKESVMAGENYEd 367
Cdd:PTZ00121 1468 EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKA-----AEAKKKADEAKKAEEakkaDEAKKAEEAKKADEAKK- 1541
|
330 340
....*....|....*....|....*
gi 334182986 368 aMDAKQKSQDLAEKTALEELQEVRR 392
Cdd:PTZ00121 1542 -AEEKKKADELKKAEELKKAEEKKK 1565
|
|
| DEXHc_Ski2 |
cd17921 |
DEXH-box helicase domain of DEAD-like helicase Ski2 family proteins; Ski2-like RNA helicases ... |
400-567 |
9.29e-03 |
|
DEXH-box helicase domain of DEAD-like helicase Ski2 family proteins; Ski2-like RNA helicases play an important role in RNA degradation, processing, and splicing pathways. They belong to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350679 [Multi-domain] Cd Length: 181 Bit Score: 38.40 E-value: 9.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 400 RDQLLKAVEEHQVLVIVGDTGSGKTT----QIPQYLHEAGytkrGKVGCTQPRRvaamSVAARVAQEMGVKLGHEVGYSI 475
Cdd:cd17921 7 REALRALYLSGDSVLVSAPTSSGKTLiaelAILRALATSG----GKAVYIAPTR----ALVNQKEADLRERFGPLGKNVG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182986 476 RfedCTSDKTVLKY---------MT----DGMLLRelLGEPDLASYSVVIVDEAH-----ERtlsTDILFGLVKDIARFR 537
Cdd:cd17921 79 L---LTGDPSVNKLllaeadilvATpeklDLLLRN--GGERLIQDVRLVVVDEAHligdgER---GVVLELLLSRLLRIN 150
|
170 180 190
....*....|....*....|....*....|.
gi 334182986 538 PDLKLLISSATMD-AEKFSDYFDTAPIFSFP 567
Cdd:cd17921 151 KNARFVGLSATLPnAEDLAEWLGVEDLIRFD 181
|
|
| |
