|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02809 |
PLN02809 |
4-hydroxybenzoate nonaprenyltransferase |
119-429 |
0e+00 |
|
4-hydroxybenzoate nonaprenyltransferase
Pssm-ID: 178405 Cd Length: 289 Bit Score: 509.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 119 YLPEEVRGYAKLARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTK 198
Cdd:PLN02809 1 YLPPSLRPYAKLARLDKPIGTWLLAWPCMWSIALAAPPGSLPDLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 199 LRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVK 278
Cdd:PLN02809 81 LRPIASGALTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 279 GSIAPSIVLPLYLSGVCWTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWLTGFG 358
Cdd:PLN02809 161 GSLDPAVVLPLYASGVCWTLVYDTIYAHQ----------------------DKEDDLKVGVKSTALRFGDDTKLWLTGFG 218
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334186859 359 TASIGFLALSGFSADLGWQYYASLAAASGQLGWQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLGRSFQ 429
Cdd:PLN02809 219 AASIGGLALSGYNAGLGWPYYAGLAAAAGHLAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGIVLGKLFS 289
|
|
| ubiA_proteo |
TIGR01474 |
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ... |
127-425 |
1.07e-106 |
|
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 130539 Cd Length: 281 Bit Score: 316.57 E-value: 1.07e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 127 YAKLARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGL 206
Cdd:TIGR01474 4 YAKLMRADKPIGTLLLLWPCLWSLLLAAQAGGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLASGA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 207 LTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIV 286
Cdd:TIGR01474 84 VSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTGDLSTAAW 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 287 LpLYLSGVCWTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLA 366
Cdd:TIGR01474 164 V-LYLANILWTLGYDTIYAMQ----------------------DKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLA 220
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 334186859 367 LSGFSADLGWQYYASLAAASGQLGWQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLG 425
Cdd:TIGR01474 221 LAGLIAGLGPVYYLGLAAAALLLIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALG 279
|
|
| PT_UbiA_COQ2 |
cd13959 |
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ... |
131-425 |
5.51e-106 |
|
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260122 [Multi-domain] Cd Length: 272 Bit Score: 314.40 E-value: 5.51e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 131 ARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPF 210
Cdd:cd13959 1 MRLDKPIGTLLLLPPALWGLLLAAGGLPLPLLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 211 QGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIaPSIVLPLY 290
Cdd:cd13959 81 EALLFLAVQLLLGLALLLQLNPLTILLSPIALLLVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSL-PLPALLLY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 291 LSGVCWTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLALSGF 370
Cdd:cd13959 160 LAVIFWTAGYDTIYAHQ----------------------DREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGG 217
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 334186859 371 SADLGWQYYASLAAASGqLGWQIGTADLSSGA-DCSRKFVSNKWFGAIIFSGVVLG 425
Cdd:cd13959 218 LAGLGWPYYLGLGAAAH-LLWQEHRLDLPDPLrSCLAFFLSNGWVGLLLFAGLLLD 272
|
|
| UbiA |
COG0382 |
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ... |
125-424 |
6.43e-68 |
|
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 440151 Cd Length: 280 Bit Score: 217.40 E-value: 6.43e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 125 RGYAKLARLDKPIGTWLLAWPCMWSIALAAdpGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIAS 204
Cdd:COG0382 1 RAYLRLLRLDRPIGILLLLWPTLWALFLAA--GGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLAS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 205 GLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPL-MKRFTFWPQAFLGLTINWGALLGWTAVKGSIAP 283
Cdd:COG0382 79 GRISLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSLfLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 284 SIVLpLYLSGVCWTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWLTG-FGTASI 362
Cdd:COG0382 159 SAWL-LALAAFLWTLAYDTIYDLE----------------------DREGDRKIGIKTLAILFGVRDALIIAGvLYALAV 215
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 334186859 363 GFLALSGFSADLGWQYYASLAAAsGQLGWQIGTADLSS----GADCSRKFVSNKWFGAIIFSGVVL 424
Cdd:COG0382 216 LLLLLLGLLAGLGLLYLLGLLAA-LLLLYLSQLWLLRPrkkdPARALKLFKLNMLLGLLLFLGIAL 280
|
|
| UbiA |
pfam01040 |
UbiA prenyltransferase family; |
142-408 |
1.12e-39 |
|
UbiA prenyltransferase family;
Pssm-ID: 460038 [Multi-domain] Cd Length: 250 Bit Score: 142.37 E-value: 1.12e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 142 LAWPCMWSIALAAdpGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLL 221
Cdd:pfam01040 1 LLIPALAGLALAA--GGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 222 LGLGILLQLNNYSRVLGASSLLLVFSYPL-MKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIVLpLYLSGVCWTLVY 300
Cdd:pfam01040 79 LGLLLLLLLNPLTALLGLAALLLYVLYTLrLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALL-LALALFLWTWAI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 301 DTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWL-TGFGTASIGFLALSGFSADLGWQYY 379
Cdd:pfam01040 158 ALANDLR----------------------DREDDRKAGIKTLPVVLGRKAARILlALLLAVALLLLLLLLLLLLGGLYLL 215
|
250 260
....*....|....*....|....*....
gi 334186859 380 ASLAAASGQLGWQIGTADLSSGADCSRKF 408
Cdd:pfam01040 216 LALLLAALALLYAARLLRLRDPKKDAKAF 244
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02809 |
PLN02809 |
4-hydroxybenzoate nonaprenyltransferase |
119-429 |
0e+00 |
|
4-hydroxybenzoate nonaprenyltransferase
Pssm-ID: 178405 Cd Length: 289 Bit Score: 509.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 119 YLPEEVRGYAKLARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTK 198
Cdd:PLN02809 1 YLPPSLRPYAKLARLDKPIGTWLLAWPCMWSIALAAPPGSLPDLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 199 LRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVK 278
Cdd:PLN02809 81 LRPIASGALTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 279 GSIAPSIVLPLYLSGVCWTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWLTGFG 358
Cdd:PLN02809 161 GSLDPAVVLPLYASGVCWTLVYDTIYAHQ----------------------DKEDDLKVGVKSTALRFGDDTKLWLTGFG 218
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334186859 359 TASIGFLALSGFSADLGWQYYASLAAASGQLGWQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLGRSFQ 429
Cdd:PLN02809 219 AASIGGLALSGYNAGLGWPYYAGLAAAAGHLAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGIVLGKLFS 289
|
|
| ubiA_proteo |
TIGR01474 |
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ... |
127-425 |
1.07e-106 |
|
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 130539 Cd Length: 281 Bit Score: 316.57 E-value: 1.07e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 127 YAKLARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGL 206
Cdd:TIGR01474 4 YAKLMRADKPIGTLLLLWPCLWSLLLAAQAGGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLASGA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 207 LTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIV 286
Cdd:TIGR01474 84 VSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTGDLSTAAW 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 287 LpLYLSGVCWTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLA 366
Cdd:TIGR01474 164 V-LYLANILWTLGYDTIYAMQ----------------------DKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLA 220
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 334186859 367 LSGFSADLGWQYYASLAAASGQLGWQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLG 425
Cdd:TIGR01474 221 LAGLIAGLGPVYYLGLAAAALLLIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALG 279
|
|
| PT_UbiA_COQ2 |
cd13959 |
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ... |
131-425 |
5.51e-106 |
|
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260122 [Multi-domain] Cd Length: 272 Bit Score: 314.40 E-value: 5.51e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 131 ARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPF 210
Cdd:cd13959 1 MRLDKPIGTLLLLPPALWGLLLAAGGLPLPLLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 211 QGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIaPSIVLPLY 290
Cdd:cd13959 81 EALLFLAVQLLLGLALLLQLNPLTILLSPIALLLVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSL-PLPALLLY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 291 LSGVCWTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLALSGF 370
Cdd:cd13959 160 LAVIFWTAGYDTIYAHQ----------------------DREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGG 217
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 334186859 371 SADLGWQYYASLAAASGqLGWQIGTADLSSGA-DCSRKFVSNKWFGAIIFSGVVLG 425
Cdd:cd13959 218 LAGLGWPYYLGLGAAAH-LLWQEHRLDLPDPLrSCLAFFLSNGWVGLLLFAGLLLD 272
|
|
| UbiA |
COG0382 |
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ... |
125-424 |
6.43e-68 |
|
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 440151 Cd Length: 280 Bit Score: 217.40 E-value: 6.43e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 125 RGYAKLARLDKPIGTWLLAWPCMWSIALAAdpGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIAS 204
Cdd:COG0382 1 RAYLRLLRLDRPIGILLLLWPTLWALFLAA--GGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLAS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 205 GLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPL-MKRFTFWPQAFLGLTINWGALLGWTAVKGSIAP 283
Cdd:COG0382 79 GRISLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSLfLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 284 SIVLpLYLSGVCWTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWLTG-FGTASI 362
Cdd:COG0382 159 SAWL-LALAAFLWTLAYDTIYDLE----------------------DREGDRKIGIKTLAILFGVRDALIIAGvLYALAV 215
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 334186859 363 GFLALSGFSADLGWQYYASLAAAsGQLGWQIGTADLSS----GADCSRKFVSNKWFGAIIFSGVVL 424
Cdd:COG0382 216 LLLLLLGLLAGLGLLYLLGLLAA-LLLLYLSQLWLLRPrkkdPARALKLFKLNMLLGLLLFLGIAL 280
|
|
| UbiA |
pfam01040 |
UbiA prenyltransferase family; |
142-408 |
1.12e-39 |
|
UbiA prenyltransferase family;
Pssm-ID: 460038 [Multi-domain] Cd Length: 250 Bit Score: 142.37 E-value: 1.12e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 142 LAWPCMWSIALAAdpGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLL 221
Cdd:pfam01040 1 LLIPALAGLALAA--GGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 222 LGLGILLQLNNYSRVLGASSLLLVFSYPL-MKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIVLpLYLSGVCWTLVY 300
Cdd:pfam01040 79 LGLLLLLLLNPLTALLGLAALLLYVLYTLrLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALL-LALALFLWTWAI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 301 DTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWL-TGFGTASIGFLALSGFSADLGWQYY 379
Cdd:pfam01040 158 ALANDLR----------------------DREDDRKAGIKTLPVVLGRKAARILlALLLAVALLLLLLLLLLLLGGLYLL 215
|
250 260
....*....|....*....|....*....
gi 334186859 380 ASLAAASGQLGWQIGTADLSSGADCSRKF 408
Cdd:pfam01040 216 LALLLAALALLYAARLLRLRDPKKDAKAF 244
|
|
| ubiA |
PRK12873 |
4-hydroxybenzoate polyprenyltransferase; |
122-426 |
2.74e-30 |
|
4-hydroxybenzoate polyprenyltransferase;
Pssm-ID: 171787 [Multi-domain] Cd Length: 294 Bit Score: 118.61 E-value: 2.74e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 122 EEVRGYAKLARLDKPIGTWLLAWPCMWSIALAadPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRP 201
Cdd:PRK12873 5 IKLSPWFELLRWNKPTGRLILLIPAGWSLWLT--PSAPPSLLLLLLIILGGLAVSGAGCIANDLWDRRIDRKVERTKNRP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 202 IASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGAS----SLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAV 277
Cdd:PRK12873 83 LARGKISLKTAYSLLIVLLLLSLFVVLSLPQPSRNLCLSlaflALPPILIYPSAKRWFAYPQAILALCWGFAVLIPWAAA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 278 KGSIAPSIVL-PLYLSGVCWTLVYDTIYAhqlhhhrflfqllfhvsckcihFDDKEDDVKVGVKSTALRFGDNTK--LWL 354
Cdd:PRK12873 163 EGSLNGGWPLlFCWLATLLWTFGFDTVYA----------------------MADRRDDAKIGLNSSALSLGSNALktVQI 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 334186859 355 TGFGTASigFLALSGFSADLGWQYYASLAAASgqLGWQIGTADLS----SGADCSRKFVSNKWFGAIIFSGVVLGR 426
Cdd:PRK12873 221 CYFLTSI--FLALAAFIAQVGFIFWPFWLIAS--IGMQRDILKLFpekqSIKTIGNHFSNQVILGSLLLLGLILAR 292
|
|
| PT_UbiA |
cd13956 |
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ... |
131-425 |
8.84e-16 |
|
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260119 [Multi-domain] Cd Length: 271 Bit Score: 77.00 E-value: 8.84e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 131 ARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGcGALLLRGAGCTINDLLDQDIDTKVDRTklRPIASGLLTPF 210
Cdd:cd13956 1 LRLMRPYTLLYVLAPALAGAALAGAFAGPLPALLLLALL-AVFLGAGAGYALNDYTDRELDAINKPD--RPLPSGRLSPR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 211 QGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLM-KRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIVLPL 289
Cdd:cd13956 78 QALAFAAALLLVGLALALALGPLALLLLLAGLLLGLAYSLGlKRLKLGGWGVLGYATGLALLPGLGAVAAGGLVPLALLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 290 YLSGVCWTLVydTIYAHQLHhhrflfqllfhvsckcihfdDKEDDVKVGVKSTALRFGDNTKLWLTgFGTASIGFLALSG 369
Cdd:cd13956 158 ALVFLLLGLG--INLYNDLP--------------------DVEGDRAAGIRTLPVRLGPRRARRLA-AGLLLAALILVVL 214
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 334186859 370 FSADLGWQYYASLAA-ASGQLGWQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLG 425
Cdd:cd13956 215 LAVAGLLGPLALLALlAVALLALRARFARADRLPALPRGFLLLAVYRLLLFAALLLA 271
|
|
| ubiA |
PRK13106 |
prenyltransferase; Reviewed |
164-425 |
5.12e-15 |
|
prenyltransferase; Reviewed
Pssm-ID: 237283 Cd Length: 300 Bit Score: 75.15 E-value: 5.12e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 164 YMALFGcgallLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLL 243
Cdd:PRK13106 55 FLALFF-----LRTAGMTNDNLADLEIDAKNPRTKNRPLVTGAIKISEAKALITAGLILFFASAYLVNRWALLLSPIVAL 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 244 LVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIVLPLYlsGVCWTLVYDTIYahqlhhHRFLFQLLFHVSc 323
Cdd:PRK13106 130 IAMSYPYMKRYTAFANYHLASIQGLAVFSGAVAVLGLYANSLIQVLL--RVPWLFVIGTIL------WAAGFDLYNHIP- 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 324 kcihfdDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLALSGFSADLGWQYYASLAAASGQLGWQIGTAdlSSGAD 403
Cdd:PRK13106 201 ------DAEFDREMGLHSFAVVLGKWALTFAGLNQLFSVVLDLLGDLYYGLGPIAIAATILHGLIMAYAYYLA--SKKGD 272
|
250 260
....*....|....*....|..
gi 334186859 404 CSRKFVSNkwfgaiIFSGVVLG 425
Cdd:PRK13106 273 FGRAFYYN------IYSSIVLG 288
|
|
| ubiA |
PRK12888 |
4-hydroxybenzoate octaprenyltransferase; |
183-424 |
2.09e-13 |
|
4-hydroxybenzoate octaprenyltransferase;
Pssm-ID: 183814 Cd Length: 284 Bit Score: 70.13 E-value: 2.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 183 NDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFL 262
Cdd:PRK12888 59 NRIIDREIDARNPRTAGRELVTGAVSVRTAWTGALVALAVFLGAAALLNPLCLALAPLAVAPLVVYPYAKRFTNFPHAIL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 263 GLTINWGALLGWTAVKGSIAPSIVLpLYLSGVCWTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGVKST 342
Cdd:PRK12888 139 GLAQAVGPVGAWIAVTGTWSWPAVL-LGLAVGLWIGGFDLIYACQ----------------------DAEVDRRIGVRSV 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 343 ALRFGDNTKLWL-TGFGTASIGFLALSGFSADLGWQYYASLAAASGQLGWQigtADLSSGADCSRkfVSNKWFGAIIFSG 421
Cdd:PRK12888 196 PARFGVRAALWAsRVAHVVTFALFVWFGLAVGFGALWWIGLAITAGAFAYE---HAIVSPTDLSR--VNRAFFTANGFVG 270
|
...
gi 334186859 422 VVL 424
Cdd:PRK12888 271 IAL 273
|
|
| ubiA |
PRK12886 |
prenyltransferase; Reviewed |
176-428 |
8.76e-13 |
|
prenyltransferase; Reviewed
Pssm-ID: 237247 Cd Length: 291 Bit Score: 68.56 E-value: 8.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 176 RGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFT 255
Cdd:PRK12886 55 RTAAMGFNRLIDAEIDARNPRTAGRAIPAGLISKGSAILFIVLSSLLMLFAAWFLNPLCLYLSPPALFFLLLYSYCKRFT 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 256 FWPQAFLGLTINWGALLGWTAVKGSIAPSIVLpLYLSGVCWTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDV 335
Cdd:PRK12886 135 ALAHVVLGFCLALAPLGAWIAIRGTIELPAIL-LGLAVLFWVAGFDILYALQ----------------------DLEFDR 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 336 KVGVKSTALRFGDNTKLWLT-GFGTASIGFLALSGFSADLGWQYYASLAAASGQLGWQigtADLSSGADCSRK----FVS 410
Cdd:PRK12886 192 KEGLHSIPAKLGVNGSLWIArVFHLLMIGFLFALGISAGLGPWFLAGLAVTGILLLYE---HWLLRGGDLTRLdaafFNM 268
|
250
....*....|....*...
gi 334186859 411 NKWFGAIIFSGVVLGRSF 428
Cdd:PRK12886 269 NGYISVTLFAATLFDRLF 286
|
|
| CyoE |
COG0109 |
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport ... |
124-297 |
7.85e-11 |
|
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport and metabolism];
Pssm-ID: 439879 Cd Length: 299 Bit Score: 62.84 E-value: 7.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 124 VRGYAKLArldKPIGTWLL---AWPCMWsiaLAadPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLR 200
Cdd:COG0109 16 LRDYLALT---KPRIILLLlftALAGML---LA--AGGLPDLLLLLLTLLGGALAAGAANALNNYIDRDIDALMKRTKNR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 201 PIASGLLTPFQGIGFLGLQLLLGLGILLQLNN-YSRVLGASSLLL-VFSY-PLMKRFTfwPQAflgltINWGA------- 270
Cdd:COG0109 88 PLPTGRISPREALIFGLVLGVLGLALLALFVNpLAALLGLLGIFFyVVVYtLWLKRRT--PQN-----IVIGGaagampp 160
|
170 180
....*....|....*....|....*....
gi 334186859 271 LLGWTAVKGSIAPsivLPLYLSGV--CWT 297
Cdd:COG0109 161 LIGWAAVTGSLSL---EALLLFLIifLWT 186
|
|
| PT_UbiA_Cox10 |
cd13957 |
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ... |
135-297 |
1.70e-09 |
|
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260120 Cd Length: 271 Bit Score: 58.22 E-value: 1.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 135 KPIGTWLLAWPCMWSIALAadPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIG 214
Cdd:cd13957 5 KPRITLLVLLTALAGYLLA--PGGVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRISPKHALI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 215 FLGLQLLL-GLGILLQLNNYSRVLGASSLLL-VFSY-PLMKRFTFWpqaflglTINWGA-------LLGWTAVKGSIAPs 284
Cdd:cd13957 83 FGLVLGILgLALLALFVNPLTALLGLLGIFLyVFVYtPLKKRTTPL-------NTVIGGiagaippLIGWAAATGSLDL- 154
|
170
....*....|....*
gi 334186859 285 ivLPLYLSGV--CWT 297
Cdd:cd13957 155 --GAWLLFLIlfLWQ 167
|
|
| PRK04375 |
PRK04375 |
protoheme IX farnesyltransferase; Provisional |
152-297 |
9.48e-09 |
|
protoheme IX farnesyltransferase; Provisional
Pssm-ID: 235293 Cd Length: 296 Bit Score: 56.30 E-value: 9.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 152 LAADPGSLPSFKYMALFGCGALLLrGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLN 231
Cdd:PRK04375 34 LLAPPGVPPLLLLLLTLLGIALVA-GAAGALNNYIDRDIDAKMERTKNRPLVTGRISPREALIFGLVLGVLGFLLLGLFV 112
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 334186859 232 NY-SRVLGASSLLL-VFSYPL-MKRFTfwPQaflglTINWGA-------LLGWTAVKGSIAPSIVLpLYLSGVCWT 297
Cdd:PRK04375 113 NPlAAWLTLAGIFFyVVVYTLwLKRRT--PQ-----NIVIGGaagamppLIGWAAVTGSLSWEALI-LFLIIFLWT 180
|
|
| ubiA |
PRK12876 |
prenyltransferase; Reviewed |
152-264 |
5.60e-05 |
|
prenyltransferase; Reviewed
Pssm-ID: 237244 Cd Length: 300 Bit Score: 44.74 E-value: 5.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 152 LAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLN 231
Cdd:PRK12876 36 ISFSLFSLGGIKTISLGGSAFFCARTVGIIVNQIIDCAIDKKNPRTSSRVLPAKLLSINFSMLLLTLCSFLFLSLCWLLN 115
|
90 100 110
....*....|....*....|....*....|...
gi 334186859 232 NYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGL 264
Cdd:PRK12876 116 PLCFSLAVLSTLLMIIYPYTKRVTFLCHWILGL 148
|
|
| ubiA |
PRK12874 |
4-hydroxybenzoate polyprenyltransferase; |
182-385 |
2.08e-04 |
|
4-hydroxybenzoate polyprenyltransferase;
Pssm-ID: 237242 Cd Length: 291 Bit Score: 43.07 E-value: 2.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 182 INDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAF 261
Cdd:PRK12874 66 FNRLVDRDIDKDNPRTANRPSVDGRISVKSMVLFIVLNALIFIGVSYFINPLAFKLSFPFLIVLGGYSYFKRFSSLAHLV 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 262 LGLTINWGALLGWTAVKGSIAP-SIVLPLylsGVC-WTLVYDTIYAHQlhhhrflfqllfhvsckcihfdDKEDDVKVGV 339
Cdd:PRK12874 146 LGLSLGLAPIAGVVAVLGEIPLwSVFLAL---GVMfWVAGFDLLYSLQ----------------------DMEFDKKRGL 200
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 334186859 340 KSTALRFGDNTKLWLTGFGTA-SIGFLALSGFSADLG-WQYYASLAAA 385
Cdd:PRK12874 201 HSIPSKFGEKATLFISRLFHLlAVLFWLLFVWCAHLGlFAYLGVIVSA 248
|
|
| PLN02776 |
PLN02776 |
prenyltransferase |
171-291 |
1.69e-03 |
|
prenyltransferase
Pssm-ID: 215415 Cd Length: 341 Bit Score: 40.11 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334186859 171 GALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLT-PFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLL-VFSY 248
Cdd:PLN02776 37 GTMLCAASANTLNQVFEVKNDSKMKRTMRRPLPSGRISvPHAVAWAVVVGAAGVALLAYKTNMLTAGLGAGNILLyAFVY 116
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 334186859 249 PLMKRFTFWpQAFLGLTInwGA---LLGWTAVKGSIAP-SIVLP--LYL 291
Cdd:PLN02776 117 TPLKQIHPA-NTWVGAVV--GAippLMGWAAASGQLDAgAMVLAaaLYF 162
|
|
| |
