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Conserved domains on  [gi|386763727|ref|NP_001245503|]
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will die slowly, isoform B [Drosophila melanogaster]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
63-361 9.23e-111

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 329.18  E-value: 9.23e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  63 TLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWE 142
Cdd:COG2319  111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWD 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 143 LSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 222
Cdd:COG2319  191 LATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTV 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 223 RIWDTASGQCLKTLiDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIV 302
Cdd:COG2319  271 RLWDLATGELLRTL-TGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV--AFS-PDGKTLA 346

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 386763727 303 SGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAAleNDKTIKLWKSDT 361
Cdd:COG2319  347 SGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGS--ADGTVRLWDLAT 403
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
63-361 9.23e-111

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 329.18  E-value: 9.23e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  63 TLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWE 142
Cdd:COG2319  111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWD 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 143 LSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 222
Cdd:COG2319  191 LATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTV 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 223 RIWDTASGQCLKTLiDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIV 302
Cdd:COG2319  271 RLWDLATGELLRTL-TGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV--AFS-PDGKTLA 346

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 386763727 303 SGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAAleNDKTIKLWKSDT 361
Cdd:COG2319  347 SGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGS--ADGTVRLWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 64-358 6.55e-106

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 312.35  E-value: 6.55e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  64 LKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWEL 143
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 144 STGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 223
Cdd:cd00200   81 ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 224 IWDTASGQCLKTLIDDDNpPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNekYCIFANFSvTGGKWIVS 303
Cdd:cd00200  161 LWDLRTGKCVATLTGHTG-EVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHEN--GVNSVAFS-PDGYLLAS 236

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 386763727 304 GSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALenDKTIKLWK 358
Cdd:cd00200  237 GSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSA--DGTIRIWD 289
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 68-314 2.42e-20

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 92.46  E-value: 2.42e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  68 LAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS-DSRLLVSGSDDKTLKVWELSTG 146
Cdd:PLN00181 529 LASRSKLSGICWNSYIKSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQG 608

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 147 KSLKTLKGHSNyVFCCNFNPQSNLIVS-GSFDESVRIWDVRTGKC-LKTLPAHSDPVSAVHFnRDGSLIVSSSydglcri 224
Cdd:PLN00181 609 VSIGTIKTKAN-ICCVQFPSESGRSLAfGSADHKVYYYDLRNPKLpLCTMIGHSKTVSYVRF-VDSSTLVSSS------- 679

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 225 wdtasgqclktlidddnppvsfvkfspngkyilaatLDNTLKLWDYSKGKC------LKTYTGHKNEKYciFANFSVTGG 298
Cdd:PLN00181 680 ------------------------------------TDNTLKLWDLSMSISginetpLHSFMGHTNVKN--FVGLSVSDG 721

                        250
                 ....*....|....*.
gi 386763727 299 kWIVSGSEDNMVYIWN 314
Cdd:PLN00181 722 -YIATGSETNEVFVYH 736
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 187-226 5.74e-10

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 53.86  E-value: 5.74e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 386763727   187 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 226
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
188-226 2.67e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 51.96  E-value: 2.67e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 386763727  188 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 226
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
63-361 9.23e-111

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 329.18  E-value: 9.23e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  63 TLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWE 142
Cdd:COG2319  111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWD 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 143 LSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 222
Cdd:COG2319  191 LATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTV 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 223 RIWDTASGQCLKTLiDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIV 302
Cdd:COG2319  271 RLWDLATGELLRTL-TGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV--AFS-PDGKTLA 346

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 386763727 303 SGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAAleNDKTIKLWKSDT 361
Cdd:COG2319  347 SGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGS--ADGTVRLWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 64-358 6.55e-106

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 312.35  E-value: 6.55e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  64 LKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWEL 143
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 144 STGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 223
Cdd:cd00200   81 ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 224 IWDTASGQCLKTLIDDDNpPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNekYCIFANFSvTGGKWIVS 303
Cdd:cd00200  161 LWDLRTGKCVATLTGHTG-EVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHEN--GVNSVAFS-PDGYLLAS 236

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 386763727 304 GSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALenDKTIKLWK 358
Cdd:cd00200  237 GSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSA--DGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
63-361 2.65e-99

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 299.90  E-value: 2.65e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  63 TLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWE 142
Cdd:COG2319   69 ALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWD 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 143 LSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 222
Cdd:COG2319  149 LATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 223 RIWDTASGQCLKTLiDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIV 302
Cdd:COG2319  229 RLWDLATGKLLRTL-TGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSV--AFS-PDGKLLA 304

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 386763727 303 SGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAAleNDKTIKLWKSDT 361
Cdd:COG2319  305 SGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGS--DDGTVRLWDLAT 361
WD40 COG2319
WD40 repeat [General function prediction only];
66-361 9.12e-85

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 262.54  E-value: 9.12e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  66 FTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELST 145
Cdd:COG2319   30 LLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLAT 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 146 GKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 225
Cdd:COG2319  110 GLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLW 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 226 DTASGQCLKTLIDDDNpPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIVSGS 305
Cdd:COG2319  190 DLATGKLLRTLTGHTG-AVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSV--AFS-PDGRLLASGS 265

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 386763727 306 EDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAAleNDKTIKLWKSDT 361
Cdd:COG2319  266 ADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGS--DDGTVRLWDLAT 319
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 63-314 1.76e-80

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 247.63  E-value: 1.76e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  63 TLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWE 142
Cdd:cd00200   42 ELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWD 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 143 LSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 222
Cdd:cd00200  122 VETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTI 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 223 RIWDTASGQCLKTLIDDDNpPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFanFSvTGGKWIV 302
Cdd:cd00200  202 KLWDLSTGKCLGTLRGHEN-GVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLA--WS-PDGKRLA 277

                        250
                 ....*....|..
gi 386763727 303 SGSEDNMVYIWN 314
Cdd:cd00200  278 SGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
80-361 8.34e-68

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 218.63  E-value: 8.34e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  80 FSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYV 159
Cdd:COG2319    2 LSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 160 FCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD 239
Cdd:COG2319   82 LSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGH 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 240 DNPPVSfVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIVSGSEDNMVYIWNLQSKE 319
Cdd:COG2319  162 SGAVTS-VAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV--AFS-PDGKLLASGSADGTVRLWDLATGK 237

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 386763727 320 VVQKLQGHTDTVLCTACHPTENIIASAAleNDKTIKLWKSDT 361
Cdd:COG2319  238 LLRTLTGHSGSVRSVAFSPDGRLLASGS--ADGTVRLWDLAT 277
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 60-226 8.92e-56

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 184.08  E-value: 8.92e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  60 PNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLK 139
Cdd:cd00200  123 ETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIK 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 140 VWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYD 219
Cdd:cd00200  203 LWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSAD 282


                 ....*..
gi 386763727 220 GLCRIWD 226
Cdd:cd00200  283 GTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
121-361 3.31e-49

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 170.09  E-value: 3.31e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 121 AWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDP 200
Cdd:COG2319    1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 201 VSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSfVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYT 280
Cdd:COG2319   81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRS-VAFSPDGKTLASGSADGTVRLWDLATGKLLRTLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 281 GHKNEKYCIfaNFSvTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAAleNDKTIKLWKSD 360
Cdd:COG2319  160 GHSGAVTSV--AFS-PDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGS--ADGTVRLWDLA 234


                 .
gi 386763727 361 T 361
Cdd:COG2319  235 T 235
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 148-361 1.06e-41

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 147.48  E-value: 1.06e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 148 SLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDT 227
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 228 ASGQCLKTLIDDDNPpVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTytghknekycifanfsvtggkwivsgsed 307
Cdd:cd00200   81 ETGECVRTLTGHTSY-VSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTT----------------------------- 130

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 386763727 308 nmvyiwnlqskevvqkLQGHTDTVLCTACHPTENIIASAAleNDKTIKLWKSDT 361
Cdd:cd00200  131 ----------------LRGHTDWVNSVAFSPDGTFVASSS--QDGTIKLWDLRT 166
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 68-314 2.42e-20

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 92.46  E-value: 2.42e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  68 LAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS-DSRLLVSGSDDKTLKVWELSTG 146
Cdd:PLN00181 529 LASRSKLSGICWNSYIKSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQG 608

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 147 KSLKTLKGHSNyVFCCNFNPQSNLIVS-GSFDESVRIWDVRTGKC-LKTLPAHSDPVSAVHFnRDGSLIVSSSydglcri 224
Cdd:PLN00181 609 VSIGTIKTKAN-ICCVQFPSESGRSLAfGSADHKVYYYDLRNPKLpLCTMIGHSKTVSYVRF-VDSSTLVSSS------- 679

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 225 wdtasgqclktlidddnppvsfvkfspngkyilaatLDNTLKLWDYSKGKC------LKTYTGHKNEKYciFANFSVTGG 298
Cdd:PLN00181 680 ------------------------------------TDNTLKLWDLSMSISginetpLHSFMGHTNVKN--FVGLSVSDG 721

                        250
                 ....*....|....*.
gi 386763727 299 kWIVSGSEDNMVYIWN 314
Cdd:PLN00181 722 -YIATGSETNEVFVYH 736
PTZ00421 PTZ00421
coronin; Provisional
 112-230 8.93e-13

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 69.15  E-value: 8.93e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 112 GHKLGISDVAWSS-DSRLLVSGSDDKTLKVWEL-------STGKSLKTLKGHSNYVFCCNFNPQS-NLIVSGSFDESVRI 182
Cdd:PTZ00421  73 GQEGPIIDVAFNPfDPQKLFTASEDGTIMGWGIpeegltqNISDPIVHLQGHTKKVGIVSFHPSAmNVLASAGADMVVNV 152

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 386763727 183 WDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG 230
Cdd:PTZ00421 153 WDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDG 200
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 68-351 1.31e-10

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 62.80  E-value: 1.31e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  68 LAGHTKAVSAVKFSPNGEWLASSSADKLIKIWgaydgkfektisghklgisdvawssDSRLLVSGSDDKTLKVWELSTGK 147
Cdd:PLN00181 479 LLNSSNLVCAIGFDRDGEFFATAGVNKKIKIF-------------------------ECESIIKDGRDIHYPVVELASRS 533

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 148 SLKTLkghsnyvfCCNFNPQSNlIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNR-DGSLIVSSSYDGLCRIWD 226
Cdd:PLN00181 534 KLSGI--------CWNSYIKSQ-VASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWS 604

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 227 TASGQCLKTLIDDDNppVSFVKF-SPNGKYILAATLDNTLKLWDYSKGKC-LKTYTGH-KNEKYCIFANFSVtggkwIVS 303
Cdd:PLN00181 605 INQGVSIGTIKTKAN--ICCVQFpSESGRSLAFGSADHKVYYYDLRNPKLpLCTMIGHsKTVSYVRFVDSST-----LVS 677

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 386763727 304 GSEDNMVYIWNLQ------SKEVVQKLQGHTDTVLCTACHPTENIIASAALEND 351
Cdd:PLN00181 678 SSTDNTLKLWDLSmsisgiNETPLHSFMGHTNVKNFVGLSVSDGYIATGSETNE 731
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 187-226 5.74e-10

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 53.86  E-value: 5.74e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 386763727   187 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 226
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 145-184 7.85e-10

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 53.47  E-value: 7.85e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 386763727   145 TGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 184
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
126-273 9.91e-10

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 58.17  E-value: 9.91e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 126 SRLLVSGSDDKTLKVWELSTGKSLKTLK--GHSNYVFccnFNPQ-SNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVS 202
Cdd:COG3391   80 RRLYVANSGSGRVSVIDLATGKVVATIPvgGGPRGLA---VDPDgGRLYVADSGNGRVSVIDTATGKVVATIPVGAGPHG 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 203 AVhFNRDGS-LIVSSSYDGlcRIW------DTASGQCLKTLIDDDNPpvSFVKFSPNGKYILAA--------TLDNTLKL 267
Cdd:COG3391  157 IA-VDPDGKrLYVANSGSN--TVSvivsviDTATGKVVATIPVGGGP--VGVAVSPDGRRLYVAnrgsntsnGGSNTVSV 231


                 ....*.
gi 386763727 268 WDYSKG 273
Cdd:COG3391  232 IDLATL 237
WD40 pfam00400
WD domain, G-beta repeat;
188-226 2.67e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 51.96  E-value: 2.67e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 386763727  188 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 226
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
146-184 1.09e-08

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 50.42  E-value: 1.09e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 386763727  146 GKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 184
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 103-142 1.25e-08

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 50.39  E-value: 1.25e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 386763727   103 DGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWE 142
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 211-357 1.53e-08

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 56.25  E-value: 1.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 211 SLIVSSSYDGLCRIWDTASGQcLKTLIDDDNPPVSFVKFSPNGKYILAA-TLDNTLKLWDYSKGKCLKTYTGHKNeKYCI 289
Cdd:PLN00181 546 SQVASSNFEGVVQVWDVARSQ-LVTEMKEHEKRVWSIDYSSADPTLLASgSDDGSVKLWSINQGVSIGTIKTKAN-ICCV 623

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386763727 290 faNFSVTGGKWIVSGSEDNMVYIWNLQSKEV-VQKLQGHTDTVLCTACHPTENIIASAaleNDKTIKLW 357
Cdd:PLN00181 624 --QFPSESGRSLAFGSADHKVYYYDLRNPKLpLCTMIGHSKTVSYVRFVDSSTLVSSS---TDNTLKLW 687
PTZ00421 PTZ00421
coronin; Provisional
 68-249 1.61e-08

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 56.05  E-value: 1.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  68 LAGHTKAVSAVKFSP-NGEWLASSSADKLIKIWGAYDGKFEKTIS-------GH--KLGISDVAWSSDSrLLVSGSDDKT 137
Cdd:PTZ00421  71 LLGQEGPIIDVAFNPfDPQKLFTASEDGTIMGWGIPEEGLTQNISdpivhlqGHtkKVGIVSFHPSAMN-VLASAGADMV 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 138 LKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVS--AVHFNRDGSLI-- 213
Cdd:PTZ00421 150 VNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAKSqrCLWAKRKDLIItl 229

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 386763727 214 -VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKF 249
Cdd:PTZ00421 230 gCSKSQQRQIMLWDTRKMASPYSTVDLDQSSALFIPF 266
WD40 pfam00400
WD domain, G-beta repeat;
104-142 1.93e-08

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 49.65  E-value: 1.93e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 386763727  104 GKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWE 142
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
63-99 2.70e-08

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 49.27  E-value: 2.70e-08
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 386763727   63 TLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIW 99
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 61-99 4.33e-08

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 48.85  E-value: 4.33e-08
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 386763727    61 NYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIW 99
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
NBCH_WD40 pfam20426
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at ...
 103-344 1.21e-07

Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at the C-terminus of neurobeachin-like proteins.


Pssm-ID: 466575 [Multi-domain]  Cd Length: 350  Bit Score: 52.77  E-value: 1.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  103 DGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFccnfnPQSNLIVSGSfdeSVRI 182
Cdd:pfam20426 113 DGRMVQSIRQHKDVVSCVAVTSDGSILATGSYDTTVMVWEVLRGRSSEKRSRNTQTEF-----PRKDHVIAET---PFHI 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  183 wdvrtgkclktLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAAtlD 262
Cdd:pfam20426 185 -----------LCGHDDIITCLYVSVELDIVISGSKDGTCIFHTLREGRYVRSIRHPSGCPLSKLVASRHGRIVLYA--D 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  263 NTLKLWDYS-KGKCLKTYT--GHKNekyCIfaNFSvTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPT 339
Cdd:pfam20426 252 DDLSLHLYSiNGKHIASSEsnGRLN---CI--ELS-SCGEFLVCAGDQGQIVVRSMNSLEVVRRYNGIGKIITSLTVTPE 325


                  ....*
gi 386763727  340 ENIIA 344
Cdd:pfam20426 326 ECFLA 330
PTZ00420 PTZ00420
coronin; Provisional
 110-189 1.28e-06

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 49.95  E-value: 1.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 110 ISGHKLGISDVAWSS-DSRLLVSGSDDKTLKVWEL----STGKSLK----TLKGHSNYVFCCNFNPQSNLIV-SGSFDES 179
Cdd:PTZ00420  70 LKGHTSSILDLQFNPcFSEILASGSEDLTIRVWEIphndESVKEIKdpqcILKGHKKKISIIDWNPMNYYIMcSSGFDSF 149

                         90
                 ....*....|
gi 386763727 180 VRIWDVRTGK 189
Cdd:PTZ00420 150 VNIWDIENEK 159
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
88-220 9.77e-06

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 46.23  E-value: 9.77e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  88 ASSSADKLIKIWGAYDGKFEKTISGHKlGISDVAWSSD-SRLLVSGSDDKTLKVWELSTGKSLKTLKGhSNYVFCCNFNP 166
Cdd:COG3391   84 VANSGSGRVSVIDLATGKVVATIPVGG-GPRGLAVDPDgGRLYVADSGNGRVSVIDTATGKVVATIPV-GAGPHGIAVDP 161

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 167 QSN-LIVSGSFDES----VRIWDVRTGKCLKTLPAHSDPVsAVHFNRDGS-LIVSSSYDG 220
Cdd:COG3391  162 DGKrLYVANSGSNTvsviVSVIDTATGKVVATIPVGGGPV-GVAVSPDGRrLYVANRGSN 220
CDC55 COG5170
Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms];
113-308 1.19e-05

Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms];


Pssm-ID: 227498 [Multi-domain]  Cd Length: 460  Bit Score: 46.95  E-value: 1.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 113 HKLGISDVAWSSDSRLLVSgSDDKTLKVWELSTGK---SLKTLKGH--SNYVFCCN---FNPQ-SNLIVSGSFDESVRIW 183
Cdd:COG5170  171 HPYHINSISFNSDKETLLS-ADDLRINLWNLEIIDgsfNIVDIKPHnmEELTEVITsaeFHPEmCNVFMYSSSKGEIKLN 249

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 184 DVR-TGKCL---KTLPAHSDPVSAVHFnrdgSLIVSSsydglcriwdtasgqclktlidddnppVSFVKFSPNGKYILAA 259
Cdd:COG5170  250 DLRqSALCDnskKLFELTIDGVDVDFF----EEIVSS---------------------------ISDFKFSDNGRYILSR 298

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386763727 260 TLdNTLKLWDYSKGK-CLKTYTGHKN---------EKYCIFANFSVT---GGKWIVSGSEDN 308
Cdd:COG5170  299 DY-LTVKIWDVNMAKnPIKTIPMHCDlmdelndvyENDAIFDKFEISfsgDDKHVLSGSYSN 359
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 317-358 2.18e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 41.14  E-value: 2.18e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 386763727   317 SKEVVQKLQGHTDTVLCTACHPTENIIASAAleNDKTIKLWK 358
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGS--DDGTIKLWD 40
PTZ00420 PTZ00420
coronin; Provisional
 152-226 5.60e-05

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 44.94  E-value: 5.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 152 LKGHSNYVFCCNFNP-QSNLIVSGSFDESVRIWDVRTG----------KCLktLPAHSDPVSAVHFNRDGSLIV-SSSYD 219
Cdd:PTZ00420  70 LKGHTSSILDLQFNPcFSEILASGSEDLTIRVWEIPHNdesvkeikdpQCI--LKGHKKKISIIDWNPMNYYIMcSSGFD 147


                 ....*..
gi 386763727 220 GLCRIWD 226
Cdd:PTZ00420 148 SFVNIWD 154
WD40 pfam00400
WD domain, G-beta repeat;
273-314 9.18e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 39.25  E-value: 9.18e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 386763727  273 GKCLKTYTGHKNEKYCIFANFSvtgGKWIVSGSEDNMVYIWN 314
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPD---GKLLASGSDDGTVKVWD 39
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 120-207 9.38e-05

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 40.72  E-value: 9.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  120 VAWSSDSRLLVSGSDDKTL--------KVWELSTGKslktlkgHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCL 191
Cdd:pfam12894   1 MSWCPTMDLIALATEDGELllhrlnwqRVWTLSPDK-------EDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIV 73

                          90
                  ....*....|....*.
gi 386763727  192 KTLPAHSDPVSAVHFN 207
Cdd:pfam12894  74 HHFSAGSDLITCLGWG 89
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 229-269 1.11e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 39.22  E-value: 1.11e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 386763727   229 SGQCLKTLIDDDNPpVSFVKFSPNGKYILAATLDNTLKLWD 269
Cdd:smart00320   1 SGELLKTLKGHTGP-VTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
230-269 1.77e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 38.48  E-value: 1.77e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 386763727  230 GQCLKTLIDDDNPpVSFVKFSPNGKYILAATLDNTLKLWD 269
Cdd:pfam00400   1 GKLLKTLEGHTGS-VTSLAFSPDGKLLASGSDDGTVKVWD 39
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 164-253 2.43e-04

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 42.19  E-value: 2.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 164 FNPQSNLIVSGSFDESVRIWDVRTGKcLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRiWDTASGQcLKTLIDDDNPP 243
Cdd:COG3386   15 WDPDGRLYWVDIPGGRIHRYDPDGGA-VEVFAEPSGRPNGLAFDPDGRLLVADHGRGLVR-FDPADGE-VTVLADEYGKP 91

                         90
                 ....*....|...
gi 386763727 244 VSF---VKFSPNG 253
Cdd:COG3386   92 LNRpndGVVDPDG 104
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 272-314 3.62e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.68  E-value: 3.62e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 386763727   272 KGKCLKTYTGHKNEKYCIFANFSvtgGKWIVSGSEDNMVYIWN 314
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPD---GKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
318-357 4.18e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 37.32  E-value: 4.18e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 386763727  318 KEVVQKLQGHTDTVLCTACHPTENIIASAAleNDKTIKLW 357
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGS--DDGTVKVW 38
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 128-260 9.41e-04

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 39.27  E-value: 9.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 128 LLVSGSDDKTLKVWELS-TGKSLKTLKGHSNYVFCCNFNPQSNLIV-----SGSFDesVRIWDVRTGKcLKTLPAHSDPV 201
Cdd:COG0823    1 LAFTLSRDGNSDIYVVDlDGGEPRRLTNSPGIDTSPAWSPDGRRIAftsdrGGGPQ--IYVVDADGGE-PRRLTFGGGYN 77

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386763727 202 SAVHFNRDGSLIVSSSY-DGLCRIW--DTASGQcLKTLIDDDNPPVsfvkFSPNGKYILAAT 260
Cdd:COG0823   78 ASPSWSPDGKRLAFVSRsDGRFDIYvlDLDGGA-PRRLTDGPGSPS----WSPDGRRIVFSS 134
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 120-271 1.17e-03

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 40.26  E-value: 1.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 120 VAWSSDSRLLVSGSDDKTLKVWELSTGKsLKTLKGHSNYVFCCNFNPQSNLIVsGSFDESVRIWDVRTGKcLKTLPAHSD 199
Cdd:COG3386   13 PVWDPDGRLYWVDIPGGRIHRYDPDGGA-VEVFAEPSGRPNGLAFDPDGRLLV-ADHGRGLVRFDPADGE-VTVLADEYG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 200 PvSAVHFN-----RDGSLIVSSSYD-----GLCRIwdTASGQcLKTLIDDdnppVSF---VKFSPNGKY-ILAATLDNTL 265
Cdd:COG3386   90 K-PLNRPNdgvvdPDGRLYFTDMGEylptgALYRV--DPDGS-LRVLADG----LTFpngIAFSPDGRTlYVADTGAGRI 161


                 ....*.
gi 386763727 266 KLWDYS 271
Cdd:COG3386  162 YRFDLD 167
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 170-268 1.39e-03

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 38.88  E-value: 1.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 170 LIVSGSFDESVRIW--DVRTGKcLKTLPAHSDPVSAVHFNRDGSLIV-SSSYDGLCRIW--DTASGQclKTLIDDDNPPV 244
Cdd:COG0823    1 LAFTLSRDGNSDIYvvDLDGGE-PRRLTNSPGIDTSPAWSPDGRRIAfTSDRGGGPQIYvvDADGGE--PRRLTFGGGYN 77

                         90       100
                 ....*....|....*....|....*
gi 386763727 245 SFVKFSPNGKYIL-AATLDNTLKLW 268
Cdd:COG0823   78 ASPSWSPDGKRLAfVSRSDGRFDIY 102
NBCH_WD40 pfam20426
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at ...
 166-230 1.54e-03

Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at the C-terminus of neurobeachin-like proteins.


Pssm-ID: 466575 [Multi-domain]  Cd Length: 350  Bit Score: 40.06  E-value: 1.54e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386763727  166 PQSN-LIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG 230
Cdd:pfam20426  91 PSENfLISCGNWENSFQVISLNDGRMVQSIRQHKDVVSCVAVTSDGSILATGSYDTTVMVWEVLRG 156
eIF2A pfam08662
Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation ...
 103-271 2.21e-03

Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation initiation factors.


Pssm-ID: 462552 [Multi-domain]  Cd Length: 194  Bit Score: 38.79  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  103 DGKFEKTISGHKLG-ISDVAWSSDSR--LLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFccnFNPQSNLIVSGSFDE- 178
Cdd:pfam08662  47 TGGPDCVVELDKEGpIHDVAWSPNGKefAVIYGYMPAKVSFFDLKGNVIHSFGEQPRNTIF---WSPFGRLVLLAGFGNl 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  179 --SVRIWDVRTGKCLKTlpahsdpvsAVHFNrdgslivsssydglcriwdtasgqclktlidddnppVSFVKFSPNGKYI 256
Cdd:pfam08662 124 agDIEFWDVVNKKKIAT---------AEASN------------------------------------ATLCEWSPDGRYF 158

                         170       180
                  ....*....|....*....|.
gi 386763727  257 LAATL------DNTLKLWDYS 271
Cdd:pfam08662 159 LTATTaprlrvDNGFKIWHYN 179
COG5354 COG5354
Uncharacterized protein, contains Trp-Asp (WD) repeat [General function prediction only];
235-321 2.26e-03

Uncharacterized protein, contains Trp-Asp (WD) repeat [General function prediction only];


Pssm-ID: 227657 [Multi-domain]  Cd Length: 561  Bit Score: 39.86  E-value: 2.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727 235 TLIDDDNPPVSFVKFSPNGKYILAATLDNtLKLWDY-SKGKCLKTYtgHKNEKYCIFAnfsvTGGKWIVSGS-------- 305
Cdd:COG5354   26 TRFESENWPVAYVSESPLGTYLFSEHAAG-VECWGGpSKAKLVRFR--HPDVKYLDFS----PNEKYLVTWSrepiiepe 98

                         90       100
                 ....*....|....*....|...
gi 386763727 306 -------EDNMVYIWNLQSKEVV 321
Cdd:COG5354   99 ieispftSKNNVFVWDIASGMIV 121
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 65-148 2.96e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 39.64  E-value: 2.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727   65 KFTLAGHTKaVSAVKFSPNGEWLASSSADKLIKIwgaYD---GKfEKTI--SGHKLGISDVAWSSDSRLLV-SGSDDKTL 138
Cdd:COG4946   382 QLTLGDLGR-VFNPVWSPDGKKIAFTDNRGRLWV---VDlasGK-VRKVdtDGYGDGISDLAWSPDSKWLAySKPGPNQL 456

                          90
                  ....*....|...
gi 386763727  139 ---KVWELSTGKS 148
Cdd:COG4946   457 sqiFLYDVETGKT 469
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 65-125 3.49e-03

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 36.49  E-value: 3.49e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386763727   65 KFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 125
Cdd:pfam12894  31 TLSPDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWGEN 91
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 78-257 3.91e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 39.25  E-value: 3.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727   78 VKFSPNGEWLASSS-ADKLIKIW--GAYDGKFEKTISghKLGISDV---AWSSDSRLLVSGSDDKTLKVWELSTGKS--- 148
Cdd:COG4946   348 PAWSPDGKSIAYFSdASGEYELYiaPADGSGEPKQLT--LGDLGRVfnpVWSPDGKKIAFTDNRGRLWVVDLASGKVrkv 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386763727  149 LKTLKGHSNYVFccNFNPQSNLIV----SGSFDESVRIWDVRTGkclKTLPAhSDPVSavhfnrdgslivsssydglcri 224
Cdd:COG4946   426 DTDGYGDGISDL--AWSPDSKWLAyskpGPNQLSQIFLYDVETG---KTVQL-TDGRY---------------------- 477

                         170       180       190
                  ....*....|....*....|....*....|...
gi 386763727  225 wdtasgqclktliDDDNPpvsfvKFSPNGKYIL 257
Cdd:COG4946   478 -------------DDGSP-----AFSPDGKYLY 492
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 209-274 6.87e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 38.48  E-value: 6.87e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 386763727  209 DGSLIVSSSYDGlcRIW--DTASGQClkTLIDDD--NPPVSFVKFSPNGKYIL-AATLDNTL---KLWDYSKGK 274
Cdd:COG4946   399 DGKKIAFTDNRG--RLWvvDLASGKV--RKVDTDgyGDGISDLAWSPDSKWLAySKPGPNQLsqiFLYDVETGK 468
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 248-322 9.23e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 38.10  E-value: 9.23e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386763727  248 KFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYcIFANFSvTGGKWIV-SGSEDNM---VYIWNLQSKEVVQ 322
Cdd:COG4946   395 VWSPDGKKIAFTDNRGRLWVVDLASGKVRKVDTDGYGDGI-SDLAWS-PDSKWLAySKPGPNQlsqIFLYDVETGKTVQ 471
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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