female sterile (2) ketel, isoform B [Drosophila melanogaster]
importin beta family protein( domain architecture ID 707677)
importin beta family protein may function in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor
List of domain hits
Name | Accession | Description | Interval | E-value | ||||||||||||
KAP95 super family | cl27231 | Karyopherin (importin) beta [Intracellular trafficking and secretion]; |
17-876 | 0e+00 | ||||||||||||
Karyopherin (importin) beta [Intracellular trafficking and secretion]; The actual alignment was detected with superfamily member COG5215: Pssm-ID: 227540 [Multi-domain] Cd Length: 858 Bit Score: 595.38 E-value: 0e+00
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Name | Accession | Description | Interval | E-value | ||||||||||||
KAP95 | COG5215 | Karyopherin (importin) beta [Intracellular trafficking and secretion]; |
17-876 | 0e+00 | ||||||||||||
Karyopherin (importin) beta [Intracellular trafficking and secretion]; Pssm-ID: 227540 [Multi-domain] Cd Length: 858 Bit Score: 595.38 E-value: 0e+00
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IBN_N | pfam03810 | Importin-beta N-terminal domain; |
27-107 | 2.35e-14 | ||||||||||||
Importin-beta N-terminal domain; Pssm-ID: 397745 [Multi-domain] Cd Length: 72 Bit Score: 68.42 E-value: 2.35e-14
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IBN_N | smart00913 | Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can ... |
27-107 | 3.74e-10 | ||||||||||||
Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal (NLS) on the cargo through the classical NLS import of proteins. Importin-beta is a helicoidal molecule constructed from 19 HEAT repeats. Many nuclear pore proteins contain FG sequence repeats that can bind to HEAT repeats within importins.. which is important for importin-beta mediated transport. Pssm-ID: 197981 [Multi-domain] Cd Length: 67 Bit Score: 56.48 E-value: 3.74e-10
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Name | Accession | Description | Interval | E-value | ||||||||||||
KAP95 | COG5215 | Karyopherin (importin) beta [Intracellular trafficking and secretion]; |
17-876 | 0e+00 | ||||||||||||
Karyopherin (importin) beta [Intracellular trafficking and secretion]; Pssm-ID: 227540 [Multi-domain] Cd Length: 858 Bit Score: 595.38 E-value: 0e+00
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IBN_N | pfam03810 | Importin-beta N-terminal domain; |
27-107 | 2.35e-14 | ||||||||||||
Importin-beta N-terminal domain; Pssm-ID: 397745 [Multi-domain] Cd Length: 72 Bit Score: 68.42 E-value: 2.35e-14
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HEAT_EZ | pfam13513 | HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ... |
386-441 | 2.15e-10 | ||||||||||||
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role. Pssm-ID: 463906 [Multi-domain] Cd Length: 55 Bit Score: 56.99 E-value: 2.15e-10
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IBN_N | smart00913 | Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can ... |
27-107 | 3.74e-10 | ||||||||||||
Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal (NLS) on the cargo through the classical NLS import of proteins. Importin-beta is a helicoidal molecule constructed from 19 HEAT repeats. Many nuclear pore proteins contain FG sequence repeats that can bind to HEAT repeats within importins.. which is important for importin-beta mediated transport. Pssm-ID: 197981 [Multi-domain] Cd Length: 67 Bit Score: 56.48 E-value: 3.74e-10
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Blast search parameters | ||||
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