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Conserved domains on  [gi|386769941|ref|NP_001246109|]
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female sterile (2) ketel, isoform B [Drosophila melanogaster]

Protein Classification

importin beta family protein( domain architecture ID 707677)

importin beta family protein may function in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
KAP95 super family cl27231
Karyopherin (importin) beta [Intracellular trafficking and secretion];
17-876 0e+00

Karyopherin (importin) beta [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5215:

Pssm-ID: 227540 [Multi-domain]  Cd Length: 858  Bit Score: 595.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941  17 VSPDKNELLSAKNFLEQAAASNLPEFLKALSEILVNTANSAVARMAAGLQLKNHLTSKDEKVSQQYQDRWHQFPSEIREL 96
Cdd:COG5215   15 LSPDPNARLRAEAQLLELQSGDFEQFISLLVQVLCDLNSNDQLRMVAGLILKNSLHANDPELQKGCSQRWLGMRHESKEQ 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941  97 IKNNILAALGTENTR-PSCAAQCVAYVAVIELPINRWPMLIQTLVNKVVSEGSSEMHRESaLEAIGYICQDIRFGVMENQ 175
Cdd:COG5215   95 VKGMALRALKSPEPRfCTMAAQLLAAIARMELPNSLWPGLMEEMVRNVGDEQPVSGKCES-LGICGYHCESEAPEDLIQM 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 176 SNDVLTAIIHGMRKVEPSNHVRLAATTALHNSLEFTKSNFEKDMERNFIMEVVCEATQCQDSQICVAALQCLVKIMTLYY 255
Cdd:COG5215  174 SNVILFAIVMGALKNETTSAVRLAALKALMDSLMFVQGNFCYEEERNYFMQVVCEATQGNDEELQHAAFGCLNKIMMLYY 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 256 QYMEPYMAQALFPITLAAMKSDNDAVALQGIEFWSNVCDEEIDLAIESQEatdqgrAPQRVSKHY--ARGALQFLTPVLV 333
Cdd:COG5215  254 KFMQSYMENALAALTGRFMKSQNDEVAIQAVEFWSTICEEEIDGEMEDKY------LPEVPAQNHgfARAAVADVLPELL 327
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 334 EKLTKQDECDDEDTWSPAKAASVCLMVLATCCEDEIVPHVLPFIKENIESPNWRFRDAAVMTFGSVLNGLETNTLKPLVE 413
Cdd:COG5215  328 SLLEKQGEDYYGDDWNPSMAASSCLQLFAQLKGDKIMRPVLGFVEQNIRSESWANREAAVMAFGSVMHGPCEDCLTKIVP 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 414 QAMPTLIRLMYDSSVIVRDTIAWTFGRICDIIPEAAINETYLQTLLECFVKSLKSEPRVAANVCWAFIGLSDAAweAAVT 493
Cdd:COG5215  408 QALPGIENEMSDSCLWVKSTTAWCFGAIADHVAMIISPCGHLVLEVSASLIGLMDCPFRSINCSWRKENLVDHI--AKAV 485
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 494 NDGETPetyaLSPYFEYIITQLLETTDRSDGaQANLRCAAYQALMDMIKNSPLDCYLVVQRTTLVILERLNQVMQMETQI 573
Cdd:COG5215  486 REVESF----LAKFYLAILNALVKGTELALN-ESNLRVSLFSALGTLILICPDAVSDILAGFYDYTSKKLDECISVLGQI 560
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 574 NNHSDRHQFNDLQSLLCATLQSVLRKvHEQDAPQISDAIMTALLTMFNSSagKSGVVQEEAFLAVSTLVELLGAQFAKYM 653
Cdd:COG5215  561 LATEDQLLVEELQSNYIGVLEAIIRT-RRRDIEDVEDQLMELFIRILEST--KPTTAFGDVYTAISALSTSLEERFEQYA 637
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 654 PAFKDFLVMGLkNFQEYQVCCAAVGLTGDIFRALKDLMVPYSNEIMTVLINNLTEPTIHRTVKPQVLSAFGDIALSIGNH 733
Cdd:COG5215  638 SKFIPYLTRAL-NCTDRFVLNSAVGLVGDLANTLGTDFNIYADVLMSSLVQCLSSEATHRDLKPAILSVFGDIALAIGAN 716
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 734 FLPYLSMVLDMLRVASNLQTDANNFDMNEYINELRESILEAYTGIIQGLkgvdqtaHTDVMHMEPHLMHIISFIKRIAQE 813
Cdd:COG5215  717 FESYLDMIMMLFQQASELDPHSDEVYVDDYRKNAVQLVNCAYVGIGDSS-------KNRVRSVLPYVISIFHKIGMIAED 789
                        810       820       830       840       850       860
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 386769941 814 GDVSDSMLASAAGFIGDLCTSFGP-RLYPLLDDAIITQFLAEGKRS-KAQRTKMLCTWAVKEIKK 876
Cdd:COG5215  790 PNGSEAHTRAALGLIGDLAGMFPKgELKFGLDEDWVKDFLYGMMKKiSSQQTKDSARWAAEQVKR 854
 
Name Accession Description Interval E-value
KAP95 COG5215
Karyopherin (importin) beta [Intracellular trafficking and secretion];
17-876 0e+00

Karyopherin (importin) beta [Intracellular trafficking and secretion];


Pssm-ID: 227540 [Multi-domain]  Cd Length: 858  Bit Score: 595.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941  17 VSPDKNELLSAKNFLEQAAASNLPEFLKALSEILVNTANSAVARMAAGLQLKNHLTSKDEKVSQQYQDRWHQFPSEIREL 96
Cdd:COG5215   15 LSPDPNARLRAEAQLLELQSGDFEQFISLLVQVLCDLNSNDQLRMVAGLILKNSLHANDPELQKGCSQRWLGMRHESKEQ 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941  97 IKNNILAALGTENTR-PSCAAQCVAYVAVIELPINRWPMLIQTLVNKVVSEGSSEMHRESaLEAIGYICQDIRFGVMENQ 175
Cdd:COG5215   95 VKGMALRALKSPEPRfCTMAAQLLAAIARMELPNSLWPGLMEEMVRNVGDEQPVSGKCES-LGICGYHCESEAPEDLIQM 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 176 SNDVLTAIIHGMRKVEPSNHVRLAATTALHNSLEFTKSNFEKDMERNFIMEVVCEATQCQDSQICVAALQCLVKIMTLYY 255
Cdd:COG5215  174 SNVILFAIVMGALKNETTSAVRLAALKALMDSLMFVQGNFCYEEERNYFMQVVCEATQGNDEELQHAAFGCLNKIMMLYY 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 256 QYMEPYMAQALFPITLAAMKSDNDAVALQGIEFWSNVCDEEIDLAIESQEatdqgrAPQRVSKHY--ARGALQFLTPVLV 333
Cdd:COG5215  254 KFMQSYMENALAALTGRFMKSQNDEVAIQAVEFWSTICEEEIDGEMEDKY------LPEVPAQNHgfARAAVADVLPELL 327
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 334 EKLTKQDECDDEDTWSPAKAASVCLMVLATCCEDEIVPHVLPFIKENIESPNWRFRDAAVMTFGSVLNGLETNTLKPLVE 413
Cdd:COG5215  328 SLLEKQGEDYYGDDWNPSMAASSCLQLFAQLKGDKIMRPVLGFVEQNIRSESWANREAAVMAFGSVMHGPCEDCLTKIVP 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 414 QAMPTLIRLMYDSSVIVRDTIAWTFGRICDIIPEAAINETYLQTLLECFVKSLKSEPRVAANVCWAFIGLSDAAweAAVT 493
Cdd:COG5215  408 QALPGIENEMSDSCLWVKSTTAWCFGAIADHVAMIISPCGHLVLEVSASLIGLMDCPFRSINCSWRKENLVDHI--AKAV 485
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 494 NDGETPetyaLSPYFEYIITQLLETTDRSDGaQANLRCAAYQALMDMIKNSPLDCYLVVQRTTLVILERLNQVMQMETQI 573
Cdd:COG5215  486 REVESF----LAKFYLAILNALVKGTELALN-ESNLRVSLFSALGTLILICPDAVSDILAGFYDYTSKKLDECISVLGQI 560
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 574 NNHSDRHQFNDLQSLLCATLQSVLRKvHEQDAPQISDAIMTALLTMFNSSagKSGVVQEEAFLAVSTLVELLGAQFAKYM 653
Cdd:COG5215  561 LATEDQLLVEELQSNYIGVLEAIIRT-RRRDIEDVEDQLMELFIRILEST--KPTTAFGDVYTAISALSTSLEERFEQYA 637
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 654 PAFKDFLVMGLkNFQEYQVCCAAVGLTGDIFRALKDLMVPYSNEIMTVLINNLTEPTIHRTVKPQVLSAFGDIALSIGNH 733
Cdd:COG5215  638 SKFIPYLTRAL-NCTDRFVLNSAVGLVGDLANTLGTDFNIYADVLMSSLVQCLSSEATHRDLKPAILSVFGDIALAIGAN 716
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 734 FLPYLSMVLDMLRVASNLQTDANNFDMNEYINELRESILEAYTGIIQGLkgvdqtaHTDVMHMEPHLMHIISFIKRIAQE 813
Cdd:COG5215  717 FESYLDMIMMLFQQASELDPHSDEVYVDDYRKNAVQLVNCAYVGIGDSS-------KNRVRSVLPYVISIFHKIGMIAED 789
                        810       820       830       840       850       860
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 386769941 814 GDVSDSMLASAAGFIGDLCTSFGP-RLYPLLDDAIITQFLAEGKRS-KAQRTKMLCTWAVKEIKK 876
Cdd:COG5215  790 PNGSEAHTRAALGLIGDLAGMFPKgELKFGLDEDWVKDFLYGMMKKiSSQQTKDSARWAAEQVKR 854
IBN_N pfam03810
Importin-beta N-terminal domain;
27-107 2.35e-14

Importin-beta N-terminal domain;


Pssm-ID: 397745 [Multi-domain]  Cd Length: 72  Bit Score: 68.42  E-value: 2.35e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941   27 AKNFLEQAAASnlPEFLKALSEILVNTANSAVARMAAGLQLKNHLTSKDEKVSqqyqdrwHQFPSEIRELIKNNILAALG 106
Cdd:pfam03810   1 AEKQLEQFEKS--PGFWSKLLQILSNSENPLEVRQLAALYLKNLITRHWEEEK-------NSLPPEEKEQIKNNLLNLLG 71

                  .
gi 386769941  107 T 107
Cdd:pfam03810  72 S 72
IBN_N smart00913
Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can ...
27-107 3.74e-10

Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal (NLS) on the cargo through the classical NLS import of proteins. Importin-beta is a helicoidal molecule constructed from 19 HEAT repeats. Many nuclear pore proteins contain FG sequence repeats that can bind to HEAT repeats within importins.. which is important for importin-beta mediated transport.


Pssm-ID: 197981 [Multi-domain]  Cd Length: 67  Bit Score: 56.48  E-value: 3.74e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941    27 AKNFLEQAAASnlPEFLKALSEILVNTANSAVaRMAAGLQLKNHLTSkdekvsqqyqdRWHQFPSEIRELIKNNILAALG 106
Cdd:smart00913   1 AEKQLEQFQKS--PGFWLLLLEILANSEDQYV-RQLAAITLKNKITR-----------RWSSLPEEEKEEIKNSLLELLL 66

                   .
gi 386769941   107 T 107
Cdd:smart00913  67 S 67
 
Name Accession Description Interval E-value
KAP95 COG5215
Karyopherin (importin) beta [Intracellular trafficking and secretion];
17-876 0e+00

Karyopherin (importin) beta [Intracellular trafficking and secretion];


Pssm-ID: 227540 [Multi-domain]  Cd Length: 858  Bit Score: 595.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941  17 VSPDKNELLSAKNFLEQAAASNLPEFLKALSEILVNTANSAVARMAAGLQLKNHLTSKDEKVSQQYQDRWHQFPSEIREL 96
Cdd:COG5215   15 LSPDPNARLRAEAQLLELQSGDFEQFISLLVQVLCDLNSNDQLRMVAGLILKNSLHANDPELQKGCSQRWLGMRHESKEQ 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941  97 IKNNILAALGTENTR-PSCAAQCVAYVAVIELPINRWPMLIQTLVNKVVSEGSSEMHRESaLEAIGYICQDIRFGVMENQ 175
Cdd:COG5215   95 VKGMALRALKSPEPRfCTMAAQLLAAIARMELPNSLWPGLMEEMVRNVGDEQPVSGKCES-LGICGYHCESEAPEDLIQM 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 176 SNDVLTAIIHGMRKVEPSNHVRLAATTALHNSLEFTKSNFEKDMERNFIMEVVCEATQCQDSQICVAALQCLVKIMTLYY 255
Cdd:COG5215  174 SNVILFAIVMGALKNETTSAVRLAALKALMDSLMFVQGNFCYEEERNYFMQVVCEATQGNDEELQHAAFGCLNKIMMLYY 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 256 QYMEPYMAQALFPITLAAMKSDNDAVALQGIEFWSNVCDEEIDLAIESQEatdqgrAPQRVSKHY--ARGALQFLTPVLV 333
Cdd:COG5215  254 KFMQSYMENALAALTGRFMKSQNDEVAIQAVEFWSTICEEEIDGEMEDKY------LPEVPAQNHgfARAAVADVLPELL 327
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 334 EKLTKQDECDDEDTWSPAKAASVCLMVLATCCEDEIVPHVLPFIKENIESPNWRFRDAAVMTFGSVLNGLETNTLKPLVE 413
Cdd:COG5215  328 SLLEKQGEDYYGDDWNPSMAASSCLQLFAQLKGDKIMRPVLGFVEQNIRSESWANREAAVMAFGSVMHGPCEDCLTKIVP 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 414 QAMPTLIRLMYDSSVIVRDTIAWTFGRICDIIPEAAINETYLQTLLECFVKSLKSEPRVAANVCWAFIGLSDAAweAAVT 493
Cdd:COG5215  408 QALPGIENEMSDSCLWVKSTTAWCFGAIADHVAMIISPCGHLVLEVSASLIGLMDCPFRSINCSWRKENLVDHI--AKAV 485
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 494 NDGETPetyaLSPYFEYIITQLLETTDRSDGaQANLRCAAYQALMDMIKNSPLDCYLVVQRTTLVILERLNQVMQMETQI 573
Cdd:COG5215  486 REVESF----LAKFYLAILNALVKGTELALN-ESNLRVSLFSALGTLILICPDAVSDILAGFYDYTSKKLDECISVLGQI 560
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 574 NNHSDRHQFNDLQSLLCATLQSVLRKvHEQDAPQISDAIMTALLTMFNSSagKSGVVQEEAFLAVSTLVELLGAQFAKYM 653
Cdd:COG5215  561 LATEDQLLVEELQSNYIGVLEAIIRT-RRRDIEDVEDQLMELFIRILEST--KPTTAFGDVYTAISALSTSLEERFEQYA 637
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 654 PAFKDFLVMGLkNFQEYQVCCAAVGLTGDIFRALKDLMVPYSNEIMTVLINNLTEPTIHRTVKPQVLSAFGDIALSIGNH 733
Cdd:COG5215  638 SKFIPYLTRAL-NCTDRFVLNSAVGLVGDLANTLGTDFNIYADVLMSSLVQCLSSEATHRDLKPAILSVFGDIALAIGAN 716
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941 734 FLPYLSMVLDMLRVASNLQTDANNFDMNEYINELRESILEAYTGIIQGLkgvdqtaHTDVMHMEPHLMHIISFIKRIAQE 813
Cdd:COG5215  717 FESYLDMIMMLFQQASELDPHSDEVYVDDYRKNAVQLVNCAYVGIGDSS-------KNRVRSVLPYVISIFHKIGMIAED 789
                        810       820       830       840       850       860
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 386769941 814 GDVSDSMLASAAGFIGDLCTSFGP-RLYPLLDDAIITQFLAEGKRS-KAQRTKMLCTWAVKEIKK 876
Cdd:COG5215  790 PNGSEAHTRAALGLIGDLAGMFPKgELKFGLDEDWVKDFLYGMMKKiSSQQTKDSARWAAEQVKR 854
IBN_N pfam03810
Importin-beta N-terminal domain;
27-107 2.35e-14

Importin-beta N-terminal domain;


Pssm-ID: 397745 [Multi-domain]  Cd Length: 72  Bit Score: 68.42  E-value: 2.35e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941   27 AKNFLEQAAASnlPEFLKALSEILVNTANSAVARMAAGLQLKNHLTSKDEKVSqqyqdrwHQFPSEIRELIKNNILAALG 106
Cdd:pfam03810   1 AEKQLEQFEKS--PGFWSKLLQILSNSENPLEVRQLAALYLKNLITRHWEEEK-------NSLPPEEKEQIKNNLLNLLG 71

                  .
gi 386769941  107 T 107
Cdd:pfam03810  72 S 72
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
386-441 2.15e-10

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 56.99  E-value: 2.15e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 386769941  386 WRFRDAAVMTFGSVLNGlETNTLKPLVEQAMPTLIRLMYDSSVIVRDTIAWTFGRI 441
Cdd:pfam13513   1 WRVREAAALALGSLAEG-GPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
IBN_N smart00913
Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can ...
27-107 3.74e-10

Importin-beta N-terminal domain; Members of the importin-beta (karyopherin-beta) family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal (NLS) on the cargo through the classical NLS import of proteins. Importin-beta is a helicoidal molecule constructed from 19 HEAT repeats. Many nuclear pore proteins contain FG sequence repeats that can bind to HEAT repeats within importins.. which is important for importin-beta mediated transport.


Pssm-ID: 197981 [Multi-domain]  Cd Length: 67  Bit Score: 56.48  E-value: 3.74e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386769941    27 AKNFLEQAAASnlPEFLKALSEILVNTANSAVaRMAAGLQLKNHLTSkdekvsqqyqdRWHQFPSEIRELIKNNILAALG 106
Cdd:smart00913   1 AEKQLEQFQKS--PGFWLLLLEILANSEDQYV-RQLAAITLKNKITR-----------RWSSLPEEEKEEIKNSLLELLL 66

                   .
gi 386769941   107 T 107
Cdd:smart00913  67 S 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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