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Conserved domains on  [gi|386767616|ref|NP_001246229|]
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bruchpilot, isoform K [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cast super family cl37807
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 160-735 3.07e-60

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


The actual alignment was detected with superfamily member pfam10174:

Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 222.77  E-value: 3.07e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   160 LQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLE 239
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   240 EELRLR-----MRQPNLEM---------------QQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESI 299
Cdd:pfam10174   81 DELRAQrdlnqLLQQDFTTspvdgedkfstpeltEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   300 KKLLEMLQAKGMGK------------------------------------------------------------------ 313
Cdd:pfam10174  161 KKLLEMLQSKGLPKksgeedwertrriaeaemqlghlevlldqkekenihlreelhrrnqlqpdpaktkalqtviemkdt 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   314 ------------EEERQMFQQMQAMAQKQ---------------------LDEFRLEIQRRDQEILAMAAKMKTLEEQH- 359
Cdd:pfam10174  241 kisslernirdlEDEVQMLKTNGLLHTEDreeeikqmevykshskfmknkIDQLKQELSKKESELLALQTKLETLTNQNs 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   360 --QRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQ 437
Cdd:pfam10174  321 dcKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQ 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   438 RKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADY 517
Cdd:pfam10174  401 KKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   518 KIKLRAaeseveklqtrLERAVTERERLEIKLEASQSELGKSKAeleKATCEMGRSSADWESTKQRIARLELENERLKH- 596
Cdd:pfam10174  481 KEKVSA-----------LQPELTEKESSLIDLKEHASSLASSGL---KKDSKLKSLEIAVEQKKEECSKLENQLKKAHNa 546

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   597 -DLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLE-N 674
Cdd:pfam10174  547 eEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKhG 626

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767616   675 AQGEQESLRQELEKAQSgvSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSL 735
Cdd:pfam10174  627 QQEMKKKGAQLLEEARR--REDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSL 685
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 415-1128 1.86e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.61  E-value: 1.86e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   415 LTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRD 494
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   495 QRDRAEHEKQEerdlHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSS 574
Cdd:TIGR02168  310 RLANLERQLEE----LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   575 ADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQE-RADKASAELRRTQAELRVTQSDAERAREEAAA 653
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   654 LQEKLEKSQGEVYRLKAKLENAQGEQESL---RQELEKAQSGV-------SRIHADRDRAfSEVEKIKEEME-------- 715
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLerlQENLEGFSEGVkallknqSGLSGILGVL-SELISVDEGYEaaieaalg 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   716 -RTQATLGKSQLQHEKLQNSLDKAQN------EVDHLQDKLDKACTENRR------------LVLEKEKLTYDYDNLQSQ 776
Cdd:TIGR02168  545 gRLQAVVVENLNAAKKAIAFLKQNELgrvtflPLDSIKGTEIQGNDREILkniegflgvakdLVKFDPKLRKALSYLLGG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   777 ------LDKALGQAARMQKERETLSLDTDRI---------------------------REKLEKTQMERDDAVTEVEILK 823
Cdd:TIGR02168  625 vlvvddLDNALELAKKLRPGYRIVTLDGDLVrpggvitggsaktnssilerrreieelEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   824 EKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDES 903
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   904 TRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTD--------------IRRAQGEKEHFQSELERVTYELERA 969
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERleslerriaaterrLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   970 HAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDT-DTFGRETRRLKEENERLREKLDKTLMELETIRGK 1048
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKrSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1049 -SQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLElSKGEVAKM----LANQEKQRSELERAHIEREKARDKHEKLL 1123
Cdd:TIGR02168  945 lSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAaieeYEELKERYDFLTAQKEDLTEAKETLEEAI 1023


                   ....*
gi 386767616  1124 KEVDR 1128
Cdd:TIGR02168 1024 EEIDR 1028
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 891-1678 3.68e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 3.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   891 KAREDLRKLQDESTRLQEACDRAALQLSRAKECED--NARSELEHS---------RDRFDKLQTDIRRAQGEKEHFQSEL 959
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLERQAEKAERYKElkAELRELELAllvlrleelREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   960 ERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQdtdtfgRETRRLKEENERLREKLDKTL 1039
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE------RQLEELEAQLEELESKLDELA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1040 MELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIE-------R 1112
Cdd:TIGR02168  337 EELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARlerledrR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1113 EKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIdRLRDRLEKALQSRDATELEAGRLAKELEKAQ 1192
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE-ELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1193 MHLAKQQENTESTRIEF---ERMGAELGRLHDRLEkAEAEREALRQANRSGGAGAAPHPQLEKHVQKLESDVKQLAMERE 1269
Cdd:TIGR02168  496 RLQENLEGFSEGVKALLknqSGLSGILGVLSELIS-VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVT 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1270 QLVLQLEKSQEILMNFQKELQNAE------AELQKTREENRKLRNG-----HQVPPVAAPPAGPSPAEFQAMqkeIQTLQ 1338
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDREILKNIEgflgvaKDLVKFDPKLRKALSYllggvLVVDDLDNALELAKKLRPGYR---IVTLD 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1339 QKLQeseRALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQM 1418
Cdd:TIGR02168  652 GDLV---RPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1419 QQQQQAAQQAVqqaaqqqqsaagaggadpKELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQ 1498
Cdd:TIGR02168  729 SALRKDLARLE------------------AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1499 VQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEE 1578
Cdd:TIGR02168  791 IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1579 KEKKMAEFDVQLRKRKEQMDQLEKSLQTQgggAAAAGELNKKLMDTQRQLEAC---VKELQNTKEEHK-KAATETERLLQ 1654
Cdd:TIGR02168  871 LESELEALLNERASLEEALALLRSELEEL---SEELRELESKRSELRRELEELrekLAQLELRLEGLEvRIDNLQERLSE 947

                          810       820
                   ....*....|....*....|....
gi 386767616  1655 LVQMSQEEQNAKEKTIMDLQQALK 1678
Cdd:TIGR02168  948 EYSLTLEEAEALENKIEDDEEEAR 971
 
Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 160-735 3.07e-60

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 222.77  E-value: 3.07e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   160 LQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLE 239
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   240 EELRLR-----MRQPNLEM---------------QQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESI 299
Cdd:pfam10174   81 DELRAQrdlnqLLQQDFTTspvdgedkfstpeltEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   300 KKLLEMLQAKGMGK------------------------------------------------------------------ 313
Cdd:pfam10174  161 KKLLEMLQSKGLPKksgeedwertrriaeaemqlghlevlldqkekenihlreelhrrnqlqpdpaktkalqtviemkdt 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   314 ------------EEERQMFQQMQAMAQKQ---------------------LDEFRLEIQRRDQEILAMAAKMKTLEEQH- 359
Cdd:pfam10174  241 kisslernirdlEDEVQMLKTNGLLHTEDreeeikqmevykshskfmknkIDQLKQELSKKESELLALQTKLETLTNQNs 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   360 --QRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQ 437
Cdd:pfam10174  321 dcKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQ 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   438 RKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADY 517
Cdd:pfam10174  401 KKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   518 KIKLRAaeseveklqtrLERAVTERERLEIKLEASQSELGKSKAeleKATCEMGRSSADWESTKQRIARLELENERLKH- 596
Cdd:pfam10174  481 KEKVSA-----------LQPELTEKESSLIDLKEHASSLASSGL---KKDSKLKSLEIAVEQKKEECSKLENQLKKAHNa 546

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   597 -DLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLE-N 674
Cdd:pfam10174  547 eEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKhG 626

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767616   675 AQGEQESLRQELEKAQSgvSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSL 735
Cdd:pfam10174  627 QQEMKKKGAQLLEEARR--REDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSL 685
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 415-1128 1.86e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.61  E-value: 1.86e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   415 LTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRD 494
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   495 QRDRAEHEKQEerdlHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSS 574
Cdd:TIGR02168  310 RLANLERQLEE----LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   575 ADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQE-RADKASAELRRTQAELRVTQSDAERAREEAAA 653
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   654 LQEKLEKSQGEVYRLKAKLENAQGEQESL---RQELEKAQSGV-------SRIHADRDRAfSEVEKIKEEME-------- 715
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLerlQENLEGFSEGVkallknqSGLSGILGVL-SELISVDEGYEaaieaalg 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   716 -RTQATLGKSQLQHEKLQNSLDKAQN------EVDHLQDKLDKACTENRR------------LVLEKEKLTYDYDNLQSQ 776
Cdd:TIGR02168  545 gRLQAVVVENLNAAKKAIAFLKQNELgrvtflPLDSIKGTEIQGNDREILkniegflgvakdLVKFDPKLRKALSYLLGG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   777 ------LDKALGQAARMQKERETLSLDTDRI---------------------------REKLEKTQMERDDAVTEVEILK 823
Cdd:TIGR02168  625 vlvvddLDNALELAKKLRPGYRIVTLDGDLVrpggvitggsaktnssilerrreieelEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   824 EKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDES 903
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   904 TRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTD--------------IRRAQGEKEHFQSELERVTYELERA 969
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERleslerriaaterrLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   970 HAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDT-DTFGRETRRLKEENERLREKLDKTLMELETIRGK 1048
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKrSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1049 -SQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLElSKGEVAKM----LANQEKQRSELERAHIEREKARDKHEKLL 1123
Cdd:TIGR02168  945 lSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAaieeYEELKERYDFLTAQKEDLTEAKETLEEAI 1023


                   ....*
gi 386767616  1124 KEVDR 1128
Cdd:TIGR02168 1024 EEIDR 1028
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 331-1116 3.21e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 101.29  E-value: 3.21e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   331 LDEFRLEIQRRDQEIlamaAKMKTLEEQHQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQ 410
Cdd:TIGR02168  234 LEELREELEELQEEL----KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   411 ERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAhhsssegALTSLEEAIGDKEKQMA 490
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA-------ELEELESRLEELEEQLE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   491 QLRdqRDRAEHEKQEErdLHEREVADYKIKLRAAESEVEKLQTRLERAvtERERLEIKLEASQSELGKSKAELEKATCEM 570
Cdd:TIGR02168  383 TLR--SKVAQLELQIA--SLNNEIERLEARLERLEDRRERLQQEIEEL--LKKLEEAELKELQAELEELEEELEELQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   571 GRSSADWESTKQRIARLELENERLKHDLERSQTTFGRTtmttsQELDRAQERADKASAELRRTQAELRVTQSDAERAREE 650
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-----ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   651 AAALQEKLEKSQGEvyRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEK 730
Cdd:TIGR02168  532 DEGYEAAIEAALGG--RLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   731 LQNSLDKAQNE-------VDHLQDKLDKACTENRRL---VLEKEKLTYDYDNLQSQLDKALGQAARmQKERETLSLDTDR 800
Cdd:TIGR02168  610 FDPKLRKALSYllggvlvVDDLDNALELAKKLRPGYrivTLDGDLVRPGGVITGGSAKTNSSILER-RREIEELEEKIEE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   801 IREKLEKTQMERDDAVTEVEILKEKLDKALyasqkliDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEV 880
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLR-------KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   881 EAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELE 960
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   961 RVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDtdtfgretrRLKEENERLREkLDKTLM 1040
Cdd:TIGR02168  842 DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS---------ELEELSEELRE-LESKRS 911

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767616  1041 ELETIRGKSQyesESFEKYKDKYEKIEMEVQNMESKLHET-SLQLELSKGEVAKMLANQEKQRSELERahIEREKAR 1116
Cdd:TIGR02168  912 ELRRELEELR---EKLAQLELRLEGLEVRIDNLQERLSEEySLTLEEAEALENKIEDDEEEARRRLKR--LENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 614-1169 4.87e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.77  E-value: 4.87e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  614 QELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQsgv 693
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE--- 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  694 srihADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNL 773
Cdd:COG1196   316 ----ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  774 QSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEK 853
Cdd:COG1196   392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  854 YDRAQNEIYRLQsrcDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEH 933
Cdd:COG1196   472 AALLEAALAELL---EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAL 548

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  934 SRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQD 1013
Cdd:COG1196   549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1014 TDTFGRETRRLKEENERLREKLDktlmELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAK 1093
Cdd:COG1196   629 AARLEAALRRAVTLAGRLREVTL----EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE 704

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767616 1094 MLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAgeRQEIDRLRDRLEK 1169
Cdd:COG1196   705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL--ERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 418-1003 1.59e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.76  E-value: 1.59e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  418 ELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRd 497
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI- 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  498 raEHEKQEERDLHERevadykikLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKAtcemgrssadw 577
Cdd:COG1196   305 --ARLEERRRELEER--------LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA----------- 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  578 ESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEK 657
Cdd:COG1196   364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  658 LEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDK 737
Cdd:COG1196   444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  738 AQNEVDHLQDKLDKACTENRRLVLEKEKLTYDydnlQSQLDKALGQAARMQKERET-LSLDTDRIREKLEK--TQMERDD 814
Cdd:COG1196   524 GAVAVLIGVEAAYEAALEAALAAALQNIVVED----DEVAAAAIEYLKAAKAGRATfLPLDKIRARAALAAalARGAIGA 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  815 AVTEVEILKEKLDKALYASQKLIDEKDtsnkefekmlEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKARE 894
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLLGRT----------LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  895 DLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQT 974
Cdd:COG1196   670 LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749

                         570       580
                  ....*....|....*....|....*....
gi 386767616  975 KASASVEAAKEEAAHYAVELEKMRDRYEK 1003
Cdd:COG1196   750 EEALEELPEPPDLEELERELERLEREIEA 778
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
474-1002 3.65e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 71.61  E-value: 3.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  474 ALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREvADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQ 553
Cdd:PRK02224  207 RLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEH-EERREELETLEAEIEDLRETIAETEREREELAEEVRDLR 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  554 SELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLER---SQTTFGRTTMTTSQELDRAQERADKASAEL 630
Cdd:PRK02224  286 ERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEEcrvAAQAHNEEAESLREDADDLEERAEELREEA 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  631 RRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKI 710
Cdd:PRK02224  366 AELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEA 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  711 KEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTEnrrlvlekekltydydnlQSQLDKALGQAARMQKE 790
Cdd:PRK02224  446 EALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEE------------------VEEVEERLERAEDLVEA 507

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  791 RETLsldtDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIyrlqsrcdt 870
Cdd:PRK02224  508 EDRI----ERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEV--------- 574

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  871 AEADRARLEVEAERSGLaaskarEDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTD-----I 945
Cdd:PRK02224  575 AELNSKLAELKERIESL------ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEfdearI 648

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 386767616  946 RRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAhyavELEKMRDRYE 1002
Cdd:PRK02224  649 EEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELE----ELEELRERRE 701
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 891-1678 3.68e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 3.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   891 KAREDLRKLQDESTRLQEACDRAALQLSRAKECED--NARSELEHS---------RDRFDKLQTDIRRAQGEKEHFQSEL 959
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLERQAEKAERYKElkAELRELELAllvlrleelREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   960 ERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQdtdtfgRETRRLKEENERLREKLDKTL 1039
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE------RQLEELEAQLEELESKLDELA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1040 MELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIE-------R 1112
Cdd:TIGR02168  337 EELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARlerledrR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1113 EKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIdRLRDRLEKALQSRDATELEAGRLAKELEKAQ 1192
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE-ELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1193 MHLAKQQENTESTRIEF---ERMGAELGRLHDRLEkAEAEREALRQANRSGGAGAAPHPQLEKHVQKLESDVKQLAMERE 1269
Cdd:TIGR02168  496 RLQENLEGFSEGVKALLknqSGLSGILGVLSELIS-VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVT 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1270 QLVLQLEKSQEILMNFQKELQNAE------AELQKTREENRKLRNG-----HQVPPVAAPPAGPSPAEFQAMqkeIQTLQ 1338
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDREILKNIEgflgvaKDLVKFDPKLRKALSYllggvLVVDDLDNALELAKKLRPGYR---IVTLD 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1339 QKLQeseRALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQM 1418
Cdd:TIGR02168  652 GDLV---RPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1419 QQQQQAAQQAVqqaaqqqqsaagaggadpKELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQ 1498
Cdd:TIGR02168  729 SALRKDLARLE------------------AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1499 VQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEE 1578
Cdd:TIGR02168  791 IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1579 KEKKMAEFDVQLRKRKEQMDQLEKSLQTQgggAAAAGELNKKLMDTQRQLEAC---VKELQNTKEEHK-KAATETERLLQ 1654
Cdd:TIGR02168  871 LESELEALLNERASLEEALALLRSELEEL---SEELRELESKRSELRRELEELrekLAQLELRLEGLEvRIDNLQERLSE 947

                          810       820
                   ....*....|....*....|....
gi 386767616  1655 LVQMSQEEQNAKEKTIMDLQQALK 1678
Cdd:TIGR02168  948 EYSLTLEEAEALENKIEDDEEEAR 971
PTZ00121 PTZ00121
MAEBL; Provisional
 261-1067 5.74e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 5.74e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  261 YAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKgmgkEEERQMFQQMQAMAQKQLDEFRLEIQR 340
Cdd:PTZ00121 1076 YKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKA----EDARKAEEARKAEDARKAEEARKAEDA 1151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  341 RDQEILAMAAKMKTLEEQHQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSElt 420
Cdd:PTZ00121 1152 KRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAV-- 1229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  421 elkdhmdikdRKISVLQRKIENLEDLLKEKDNQvdMARARLSAMQAHHSSSEGALTSlEEAIGDKEKQMAQLRDQRDRAE 500
Cdd:PTZ00121 1230 ----------KKAEEAKKDAEEAKKAEEERNNE--EIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKADEAK 1296

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  501 HEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKAtcemgrssadweST 580
Cdd:PTZ00121 1297 KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA------------EE 1364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  581 KQRIARLELENERLKHDlersQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRvtQSDAERAREEAAALQEKLEK 660
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKAD----AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK--KADEAKKKAEEKKKADEAKK 1438

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  661 SQGEVYR---LKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQlqheklqnsldK 737
Cdd:PTZ00121 1439 KAEEAKKadeAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAA-----------E 1507

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  738 AQNEVDHLQDKLDKACTENRRLVLEKEKLtydyDNLQSQLDKAlgQAARMQKERETLSLDTDRIREKLEKTQMERDDAVT 817
Cdd:PTZ00121 1508 AKKKADEAKKAEEAKKADEAKKAEEAKKA----DEAKKAEEKK--KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALR 1581

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  818 EVEILKEKLDKALYASQKLIDEKDTSNKEFEKmlekydraqneiyrlqsrcdtaEADRARLEVEAERSGLAASKAREDLR 897
Cdd:PTZ00121 1582 KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK----------------------KAEEAKIKAEELKKAEEEKKKVEQLK 1639

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  898 KLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQgEKEHFQSELERVTYELERAHAAQTKAS 977
Cdd:PTZ00121 1640 KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA-EALKKEAEEAKKAEELKKKEAEEKKKA 1718

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  978 ASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFE 1057
Cdd:PTZ00121 1719 EELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798

                         810
                  ....*....|
gi 386767616 1058 KYKDKYEKIE 1067
Cdd:PTZ00121 1799 KIKDIFDNFA 1808
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1062-1637 2.45e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 2.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1062 KYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQssvspgDP 1141
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI------AR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1142 VRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHD 1221
Cdd:COG1196   307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1222 RLEKAEAEREALRQANRsggagaaphpQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTRE 1301
Cdd:COG1196   387 ELLEALRAAAELAAQLE----------ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1302 ENRKLRnghqvppvaaPPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASRE--EIEQWRKVIEQE 1379
Cdd:COG1196   457 EEEALL----------ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAalLLAGLRGLAGAV 526

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1380 KSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQA 1459
Cdd:COG1196   527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS 606

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1460 ACTERDRFQQQLELLVTElekskmSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQK 1539
Cdd:COG1196   607 DLREADARYYVLGDTLLG------RTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1540 QLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMDQLEKSLQTQGGGAAAAGELNK 1619
Cdd:COG1196   681 LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760

                         570
                  ....*....|....*...
gi 386767616 1620 KLMDTQRQLeacvKELQN 1637
Cdd:COG1196   761 DLEELEREL----ERLER 774
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 396-1235 6.84e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 57.67  E-value: 6.84e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   396 RLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGAL 475
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   476 T----SLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEA 551
Cdd:pfam02463  249 EqeeiESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   552 SQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELR 631
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   632 RTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIK 711
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLEL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   712 EEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLdkacTENRRLVLEKEKLTYDYDNLqsqldkalgqAARMQKER 791
Cdd:pfam02463  489 LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIIS----AHGRLGDLGVAVENYKVAIS----------TAVIVEVS 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   792 ETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTA 871
Cdd:pfam02463  555 ATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   872 EADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNArsELEHSRDRFDKLQTDIRRAQGE 951
Cdd:pfam02463  635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELA--KEEILRRQLEIKKKEQREKEEL 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   952 KEHFQSELERvtyELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERL 1031
Cdd:pfam02463  713 KKLKLEAEEL---LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVE 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1032 REKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIE 1111
Cdd:pfam02463  790 EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1112 REKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKA 1191
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 386767616  1192 QMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQ 1235
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKD 993
PTZ00121 PTZ00121
MAEBL; Provisional
 944-1678 4.10e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 4.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  944 DIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRR 1023
Cdd:PTZ00121 1086 DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARK 1165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1024 LKEENERLREKLDKTLMELETIRgksqyESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRS 1103
Cdd:PTZ00121 1166 AEEARKAEDAKKAEAARKAEEVR-----KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAE 1240

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1104 ELERAHIEREKARDKHEKLLKEVDRLRLQQSSVS----PGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATEL 1179
Cdd:PTZ00121 1241 EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAeearKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEA 1320

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1180 EagrlaKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLEs 1259
Cdd:PTZ00121 1321 K-----KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD- 1394

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1260 DVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEA-----ELQKTREENRKlrnGHQVPPVAAPPAGPSPAEFQAMQKEI 1334
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkkkadEAKKKAEEAKK---ADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1335 QTLQQKLQESERALQAAGPQQAQAAAAAGASREEIEQWRKVIE----QEKSRADMADKAaqEMHKRIQLMDQHIKDQHAQ 1410
Cdd:PTZ00121 1472 ADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEakkaEEAKKADEAKKA--EEAKKADEAKKAEEKKKAD 1549

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1411 MQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRFQQQLELLVTELEKSKmsnQEQAK 1490
Cdd:PTZ00121 1550 ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK---AEELK 1626

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1491 QLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQID 1570
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE 1706

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1571 AKRKDIEEKekkmaefdvqlrKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAATETE 1650
Cdd:PTZ00121 1707 LKKKEAEEK------------KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIR 1774

                         730       740
                  ....*....|....*....|....*...
gi 386767616 1651 RLLQLVqMSQEEQNAKEKTIMDLQQALK 1678
Cdd:PTZ00121 1775 KEKEAV-IEEELDEEDEKRRMEVDKKIK 1801
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 708-1587 1.95e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.50  E-value: 1.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   708 EKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLtydydnLQSQLDKALGQAARM 787
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKL------NEERIDLLQELLRDE 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   788 QKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSR 867
Cdd:pfam02463  250 QEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   868 CDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRR 947
Cdd:pfam02463  330 LKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   948 AQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDtdtfgrETRRLKEE 1027
Cdd:pfam02463  410 LLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLK------ETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1028 NERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELER 1107
Cdd:pfam02463  484 EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1108 AHIEREKARDKHEK----LLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGR 1183
Cdd:pfam02463  564 QKLVRALTELPLGArklrLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1184 LAKELEKAQMHLAKQQENTESTRIEFErMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLESDVKQ 1263
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSE-LTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1264 LAMEREqlvLQLEKSQEILMNFQKELQNAEAELQKTREENRKLRNghqvppvaappAGPSPAEFQAMQKEIQTLQQKLQE 1343
Cdd:pfam02463  723 LADRVQ---EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEE-----------EKSELSLKEKELAEEREKTEKLKV 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1344 SERALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMdqhIKDQHAQMQKMQQQMQQQQQ 1423
Cdd:pfam02463  789 EEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE---QKLEKLAEEELERLEEEITK 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1424 AAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRFQQQLEllvtelEKSKMSNQEQAKQLQTAQQQVQQLQ 1503
Cdd:pfam02463  866 EELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEE------KENEIEERIKEEAEILLKYEEEPEE 939

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1504 QQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKM 1583
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019


                   ....
gi 386767616  1584 AEFD 1587
Cdd:pfam02463 1020 KEFL 1023
 
Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 160-735 3.07e-60

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 222.77  E-value: 3.07e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   160 LQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLE 239
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   240 EELRLR-----MRQPNLEM---------------QQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESI 299
Cdd:pfam10174   81 DELRAQrdlnqLLQQDFTTspvdgedkfstpeltEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   300 KKLLEMLQAKGMGK------------------------------------------------------------------ 313
Cdd:pfam10174  161 KKLLEMLQSKGLPKksgeedwertrriaeaemqlghlevlldqkekenihlreelhrrnqlqpdpaktkalqtviemkdt 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   314 ------------EEERQMFQQMQAMAQKQ---------------------LDEFRLEIQRRDQEILAMAAKMKTLEEQH- 359
Cdd:pfam10174  241 kisslernirdlEDEVQMLKTNGLLHTEDreeeikqmevykshskfmknkIDQLKQELSKKESELLALQTKLETLTNQNs 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   360 --QRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQ 437
Cdd:pfam10174  321 dcKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQ 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   438 RKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADY 517
Cdd:pfam10174  401 KKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   518 KIKLRAaeseveklqtrLERAVTERERLEIKLEASQSELGKSKAeleKATCEMGRSSADWESTKQRIARLELENERLKH- 596
Cdd:pfam10174  481 KEKVSA-----------LQPELTEKESSLIDLKEHASSLASSGL---KKDSKLKSLEIAVEQKKEECSKLENQLKKAHNa 546

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   597 -DLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLE-N 674
Cdd:pfam10174  547 eEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKhG 626

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767616   675 AQGEQESLRQELEKAQSgvSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSL 735
Cdd:pfam10174  627 QQEMKKKGAQLLEEARR--REDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSL 685
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 415-1128 1.86e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.61  E-value: 1.86e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   415 LTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRD 494
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   495 QRDRAEHEKQEerdlHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSS 574
Cdd:TIGR02168  310 RLANLERQLEE----LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   575 ADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQE-RADKASAELRRTQAELRVTQSDAERAREEAAA 653
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   654 LQEKLEKSQGEVYRLKAKLENAQGEQESL---RQELEKAQSGV-------SRIHADRDRAfSEVEKIKEEME-------- 715
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLerlQENLEGFSEGVkallknqSGLSGILGVL-SELISVDEGYEaaieaalg 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   716 -RTQATLGKSQLQHEKLQNSLDKAQN------EVDHLQDKLDKACTENRR------------LVLEKEKLTYDYDNLQSQ 776
Cdd:TIGR02168  545 gRLQAVVVENLNAAKKAIAFLKQNELgrvtflPLDSIKGTEIQGNDREILkniegflgvakdLVKFDPKLRKALSYLLGG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   777 ------LDKALGQAARMQKERETLSLDTDRI---------------------------REKLEKTQMERDDAVTEVEILK 823
Cdd:TIGR02168  625 vlvvddLDNALELAKKLRPGYRIVTLDGDLVrpggvitggsaktnssilerrreieelEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   824 EKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDES 903
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   904 TRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTD--------------IRRAQGEKEHFQSELERVTYELERA 969
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERleslerriaaterrLEDLEEQIEELSEDIESLAAEIEEL 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   970 HAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDT-DTFGRETRRLKEENERLREKLDKTLMELETIRGK 1048
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKrSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1049 -SQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLElSKGEVAKM----LANQEKQRSELERAHIEREKARDKHEKLL 1123
Cdd:TIGR02168  945 lSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAaieeYEELKERYDFLTAQKEDLTEAKETLEEAI 1023


                   ....*
gi 386767616  1124 KEVDR 1128
Cdd:TIGR02168 1024 EEIDR 1028
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 470-1308 3.73e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.37  E-value: 3.73e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   470 SSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKL 549
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   550 EASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQttfgRTTMTTSQELDRAQERADKASAE 629
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE----RQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   630 LRRTQAELRVTQsdaerarEEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEK 709
Cdd:TIGR02168  339 LAELEEKLEELK-------EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   710 IKEEMERTQATlgKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQK 789
Cdd:TIGR02168  412 LEDRRERLQQE--IEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   790 ERETLsldtDRIREKLEKTQMerddavTEVEILKEKLDKALYASqkLIDEKDTSNKEFEKMLEKYDRAqneiyRLQSRCD 869
Cdd:TIGR02168  490 RLDSL----ERLQENLEGFSE------GVKALLKNQSGLSGILG--VLSELISVDEGYEAAIEAALGG-----RLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   870 TAEADrARLEVEAERSglaASKAREDLRKLQDESTRLQEACDRAALQlsrAKECEDNARSELEHSRDRFDKL-------- 941
Cdd:TIGR02168  553 ENLNA-AKKAIAFLKQ---NELGRVTFLPLDSIKGTEIQGNDREILK---NIEGFLGVAKDLVKFDPKLRKAlsyllggv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   942 --QTDIRRAQGEKEHFQSELERVTY--ELERAHAAQTKASASVEAAkeeAAHYAVELEKMRDRYEKSQVELRKLQDT-DT 1016
Cdd:TIGR02168  626 lvVDDLDNALELAKKLRPGYRIVTLdgDLVRPGGVITGGSAKTNSS---ILERRREIEELEEKIEELEEKIAELEKAlAE 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1017 FGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLA 1096
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1097 NQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVspgdpvrastsssSALSAGERQEIDRLRDRLEKALQSRDA 1176
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL-------------RERLESLERRIAATERRLEDLEEQIEE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1177 TELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRsggagaaphpQLEKHVQK 1256
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS----------ELRRELEE 919

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|...
gi 386767616  1257 LESDVKQLAMEREQLVLQLEKSQEILMN-FQKELQNAEAELQKTREENRKLRN 1308
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNLQERLSEeYSLTLEEAEALENKIEDDEEEARR 972
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 431-1234 1.34e-21

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 102.84  E-value: 1.34e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   431 RKISVLQRKIENLEDLLKEKDNQVD-MARARLSAMQAHHSSS---EGALTSLEEAIGDKEKQMAQLRDQRDRAEHEK--- 503
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLErLRREREKAERYQALLKekrEYEGYELLKEKEALERQKEAIERQLASLEEELekl 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   504 QEERDLHEREVADYKIKLRAAESEVEKL--------QTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSA 575
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLgeeeqlrvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   576 DWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQEldraqeraDKASAELRRTQAELRVTQSDaerareeaaaLQ 655
Cdd:TIGR02169  337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEV--------DKEFAETRDELKDYREKLEK----------LK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   656 EKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSL 735
Cdd:TIGR02169  399 REINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   736 DKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDA 815
Cdd:TIGR02169  479 DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   816 VTE--VEILKEKldKALYASQKLIDEKDTSNKEFEKMLE---------------KYDRAQNEIYR---LQSRCDTAEA-- 873
Cdd:TIGR02169  559 VAKeaIELLKRR--KAGRATFLPLNKMRDERRDLSILSEdgvigfavdlvefdpKYEPAFKYVFGdtlVVEDIEAARRlm 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   874 DRARLEVEA----ERSG------LAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQT 943
Cdd:TIGR02169  637 GKYRMVTLEgelfEKSGamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   944 DIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQD--TDTFGRET 1021
Cdd:TIGR02169  717 KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEArlSHSRIPEI 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1022 RRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQ 1101
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1102 RSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSpgDPVRASTSSSSALSAGERQEIDRLrDRLEKALQSRDATELEA 1181
Cdd:TIGR02169  877 LRDLESRLGDLKKERDELEAQLRELERKIEELEAQI--EKKRKRLSELKAKLEALEEELSEI-EDPKGEDEEIPEEELSL 953

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|...
gi 386767616  1182 GRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALR 1234
Cdd:TIGR02169  954 EDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 331-1116 3.21e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 101.29  E-value: 3.21e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   331 LDEFRLEIQRRDQEIlamaAKMKTLEEQHQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQ 410
Cdd:TIGR02168  234 LEELREELEELQEEL----KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   411 ERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAhhsssegALTSLEEAIGDKEKQMA 490
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA-------ELEELESRLEELEEQLE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   491 QLRdqRDRAEHEKQEErdLHEREVADYKIKLRAAESEVEKLQTRLERAvtERERLEIKLEASQSELGKSKAELEKATCEM 570
Cdd:TIGR02168  383 TLR--SKVAQLELQIA--SLNNEIERLEARLERLEDRRERLQQEIEEL--LKKLEEAELKELQAELEELEEELEELQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   571 GRSSADWESTKQRIARLELENERLKHDLERSQTTFGRTtmttsQELDRAQERADKASAELRRTQAELRVTQSDAERAREE 650
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-----ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   651 AAALQEKLEKSQGEvyRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEK 730
Cdd:TIGR02168  532 DEGYEAAIEAALGG--RLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   731 LQNSLDKAQNE-------VDHLQDKLDKACTENRRL---VLEKEKLTYDYDNLQSQLDKALGQAARmQKERETLSLDTDR 800
Cdd:TIGR02168  610 FDPKLRKALSYllggvlvVDDLDNALELAKKLRPGYrivTLDGDLVRPGGVITGGSAKTNSSILER-RREIEELEEKIEE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   801 IREKLEKTQMERDDAVTEVEILKEKLDKALyasqkliDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEV 880
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLR-------KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   881 EAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELE 960
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   961 RVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDtdtfgretrRLKEENERLREkLDKTLM 1040
Cdd:TIGR02168  842 DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS---------ELEELSEELRE-LESKRS 911

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767616  1041 ELETIRGKSQyesESFEKYKDKYEKIEMEVQNMESKLHET-SLQLELSKGEVAKMLANQEKQRSELERahIEREKAR 1116
Cdd:TIGR02168  912 ELRRELEELR---EKLAQLELRLEGLEVRIDNLQERLSEEySLTLEEAEALENKIEDDEEEARRRLKR--LENKIKE 983
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 554-1296 2.11e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.05  E-value: 2.11e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   554 SELGKSKAELEKATCEMGRSSADWESTKQRIARLELEN---ERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAEL 630
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERekaERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   631 RRTQAELRVTQSDAERAREEAAALQEKLEK-----SQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFS 705
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   706 EVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAA 785
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELD 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   786 RMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQ 865
Cdd:TIGR02169  410 RLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   866 SRCDTAEAdRARLEVEAERSGLAASKARED--------LRKLQDESTRLQEACDRAA---LQL------SRAKECEDNAR 928
Cdd:TIGR02169  490 RELAEAEA-QARASEERVRGGRAVEEVLKAsiqgvhgtVAQLGSVGERYATAIEVAAgnrLNNvvveddAVAKEAIELLK 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   929 SElEHSRDRFDKLqTDIRRAQGEKEHFQSE------LERVTYELERAHA-----AQTKASASVEAAKEEAAHY-AVELEK 996
Cdd:TIGR02169  569 RR-KAGRATFLPL-NKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAfkyvfGDTLVVEDIEAARRLMGKYrMVTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   997 mrDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTLMELETIRGK-SQYESESFEKYKdkyekiemEVQNMES 1075
Cdd:TIGR02169  647 --ELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSElRRIENRLDELSQ--------ELSDASR 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1076 KLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSP--GDPVRASTSSSSALS 1153
Cdd:TIGR02169  717 KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEalNDLEARLSHSRIPEI 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1154 AGERQEIDRLRDRLEKALQSRDAT----ELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAE 1229
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKlnrlTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA 876

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767616  1230 REALRqanrsggagaAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAEL 1296
Cdd:TIGR02169  877 LRDLE----------SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 614-1169 4.87e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.77  E-value: 4.87e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  614 QELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQsgv 693
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE--- 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  694 srihADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNL 773
Cdd:COG1196   316 ----ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  774 QSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEK 853
Cdd:COG1196   392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  854 YDRAQNEIYRLQsrcDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEH 933
Cdd:COG1196   472 AALLEAALAELL---EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAL 548

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  934 SRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQD 1013
Cdd:COG1196   549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1014 TDTFGRETRRLKEENERLREKLDktlmELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAK 1093
Cdd:COG1196   629 AARLEAALRRAVTLAGRLREVTL----EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE 704

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767616 1094 MLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAgeRQEIDRLRDRLEK 1169
Cdd:COG1196   705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL--ERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 622-1343 7.12e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 7.12e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   622 RADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRD 701
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   702 RAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKAL 781
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   782 GQAARMQKERETLSLDTDRIREKLEKTQME------------RDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEK 849
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEieellkkleeaeLKELQAELEELEEELEELQEELERLEEALEELREELEE 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   850 MLEKYDRAQNEIYRLQSRCDTAEADRARLE--------VEAERSGLAASKAR-EDLRKLQDESTRLQEACDRAALQ---- 916
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEgfsegvkaLLKNQSGLSGILGVlSELISVDEGYEAAIEAALGGRLQavvv 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   917 --LSRAKEC-------EDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAA-----------QTKA 976
Cdd:TIGR02168  553 enLNAAKKAiaflkqnELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvvDDLD 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   977 SASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGR--ETRRLKEENERLREKLDKTLMELETIRgksqyesE 1054
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERrrEIEELEEKIEELEEKIAELEKALAELR-------K 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1055 SFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQS 1134
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1135 SVSPG-DPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMG 1213
Cdd:TIGR02168  786 ELEAQiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1214 AELGRLHDRLEKAEAEREALRQANRSggagaaphpqLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAE 1293
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALAL----------LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 386767616  1294 AELQKTREenrKLRNGHQVPPVA-APPAGPSPAEFQAMQKEIQTLQQKLQE 1343
Cdd:TIGR02168  936 VRIDNLQE---RLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 418-1003 1.59e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.76  E-value: 1.59e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  418 ELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRd 497
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI- 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  498 raEHEKQEERDLHERevadykikLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKAtcemgrssadw 577
Cdd:COG1196   305 --ARLEERRRELEER--------LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA----------- 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  578 ESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEK 657
Cdd:COG1196   364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  658 LEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDK 737
Cdd:COG1196   444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  738 AQNEVDHLQDKLDKACTENRRLVLEKEKLTYDydnlQSQLDKALGQAARMQKERET-LSLDTDRIREKLEK--TQMERDD 814
Cdd:COG1196   524 GAVAVLIGVEAAYEAALEAALAAALQNIVVED----DEVAAAAIEYLKAAKAGRATfLPLDKIRARAALAAalARGAIGA 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  815 AVTEVEILKEKLDKALYASQKLIDEKDtsnkefekmlEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKARE 894
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLLGRT----------LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  895 DLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQT 974
Cdd:COG1196   670 LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749

                         570       580
                  ....*....|....*....|....*....
gi 386767616  975 KASASVEAAKEEAAHYAVELEKMRDRYEK 1003
Cdd:COG1196   750 EEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 680-1483 2.29e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.49  E-value: 2.29e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   680 ESLRQELEKAqSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDhLQDKLDKactenrrl 759
Cdd:TIGR02168  155 EERRAIFEEA-AGISKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKE-LKAELRE-------- 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   760 vLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEktqmERDDAVTEVEILKEKLDKALYASQKLIDE 839
Cdd:TIGR02168  225 -LELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE----ELRLEVSELEEEIEELQKELYALANEISR 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   840 KDtsnkefekmlekydraqNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSR 919
Cdd:TIGR02168  300 LE-----------------QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEE 362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   920 AKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAhyAVELEKMRD 999
Cdd:TIGR02168  363 LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE--EAELKELQA 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1000 RYEKSQVELRKLQDTDTFGRET-RRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNmesklh 1078
Cdd:TIGR02168  441 ELEELEEELEELQEELERLEEAlEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN------ 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1079 etSLQLELSKGEVAKMLANQEKQRSELERA--------HIEREKARDKHEKLLKEVDRLR---LQQSSVSPGDP--VRAS 1145
Cdd:TIGR02168  515 --QSGLSGILGVLSELISVDEGYEAAIEAAlggrlqavVVENLNAAKKAIAFLKQNELGRvtfLPLDSIKGTEIqgNDRE 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1146 TSSSSALSAGERQEIDRLRDRLEKALQSRDATEL------EAGRLAKELEKAQMHLAKQQEN-TESTRIEFERMGAELGR 1218
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvddldNALELAKKLRPGYRIVTLDGDLvRPGGVITGGSAKTNSSI 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1219 LHDR--LEKAEAEREALRQANRsggagaaphpQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAEL 1296
Cdd:TIGR02168  673 LERRreIEELEEKIEELEEKIA----------ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1297 QKTREENRKLR----NGHQVPPVAAPPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASREEIEQW 1372
Cdd:TIGR02168  743 EQLEERIAQLSkeltELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1373 RKVIEQEKSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGgadpKELEK 1452
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLR----SELEE 898

                          810       820       830
                   ....*....|....*....|....*....|.
gi 386767616  1453 VRGELQAACTERDRFQQQLELLVTELEKSKM 1483
Cdd:TIGR02168  899 LSEELRELESKRSELRRELEELREKLAQLEL 929
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 667-1342 2.95e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.11  E-value: 2.95e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   667 RLKAKLENAQGEQEsLRQELEKAQSGVS-----RIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNE 741
Cdd:TIGR02168  204 SLERQAEKAERYKE-LKAELRELELALLvlrleELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   742 VDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEI 821
Cdd:TIGR02168  283 IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   822 LKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKA--------- 892
Cdd:TIGR02168  363 LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAelkelqael 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   893 ---REDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQ------------- 956
Cdd:TIGR02168  443 eelEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKallknqsglsgil 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   957 ---SELERVTYELERA-HAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENE--- 1029
Cdd:TIGR02168  523 gvlSELISVDEGYEAAiEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGflg 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1030 ---------------------------------RLREKLDKTLM------ELETIRGKSQYESESFE----KYKDKYEKI 1066
Cdd:TIGR02168  603 vakdlvkfdpklrkalsyllggvlvvddldnalELAKKLRPGYRivtldgDLVRPGGVITGGSAKTNssilERRREIEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1067 EMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSpgdpvrast 1146
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS--------- 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1147 ssssALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKA 1226
Cdd:TIGR02168  754 ----KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1227 EAEREALRQANRsggagaaphpQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRKL 1306
Cdd:TIGR02168  830 ERRIAATERRLE----------DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL 899

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 386767616  1307 RNGHQVPPVAAPPAGPSPAEFQAMQKEIQTLQQKLQ 1342
Cdd:TIGR02168  900 SEELRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 399-778 1.72e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 1.72e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   399 EKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSL 478
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   479 EEAIGDKEKQMAQLRDQRDRAEHEKQEERDlherevadykiKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGK 558
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEE-----------ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   559 SKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSqttfgrttmttSQELDRAQERADKASAELRRTQAELR 638
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL-----------AAEIEELEELIEELESELEALLNERA 883

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   639 VTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIhadrdrafseVEKIKEEMERTQ 718
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL----------QERLSEEYSLTL 953

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   719 ATLGKsqlQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLD 778
Cdd:TIGR02168  954 EEAEA---LENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKE 1010
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 199-826 1.39e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.39e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   199 ELKKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLEEEL-RLRMRQPNLEMQQQMeaIYAENDHLQREISILRET 277
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyALANEISRLEQQKQI--LRERLANLERQLEELEAQ 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   278 IKDLECRVETQKQTLIARD---ESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKT 354
Cdd:TIGR02168  325 LEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   355 LEEQHQRHIAVLKESLCAKEEHYNMLQ-TDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKI 433
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   434 SVLQRKIENLEDLLKEKDN------QVDMARARLSAMQAHHSSS----EGALTSLEEAIG---------DKEKQMA---- 490
Cdd:TIGR02168  485 AQLQARLDSLERLQENLEGfsegvkALLKNQSGLSGILGVLSELisvdEGYEAAIEAALGgrlqavvveNLNAAKKaiaf 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   491 ------------QLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEK--------------LQTRLERAVTERER 544
Cdd:TIGR02168  565 lkqnelgrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddLDNALELAKKLRPG 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   545 LEI-----------------KLEASQSELGKSKaELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQTTFGR 607
Cdd:TIGR02168  645 YRIvtldgdlvrpggvitggSAKTNSSILERRR-EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   608 TTMTTSQ---ELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQ 684
Cdd:TIGR02168  724 LSRQISAlrkDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   685 ELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKE 764
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386767616   765 KLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKL 826
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
474-1002 3.65e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 71.61  E-value: 3.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  474 ALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREvADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQ 553
Cdd:PRK02224  207 RLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEH-EERREELETLEAEIEDLRETIAETEREREELAEEVRDLR 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  554 SELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLER---SQTTFGRTTMTTSQELDRAQERADKASAEL 630
Cdd:PRK02224  286 ERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEEcrvAAQAHNEEAESLREDADDLEERAEELREEA 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  631 RRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKI 710
Cdd:PRK02224  366 AELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEA 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  711 KEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTEnrrlvlekekltydydnlQSQLDKALGQAARMQKE 790
Cdd:PRK02224  446 EALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEE------------------VEEVEERLERAEDLVEA 507

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  791 RETLsldtDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIyrlqsrcdt 870
Cdd:PRK02224  508 EDRI----ERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEV--------- 574

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  871 AEADRARLEVEAERSGLaaskarEDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTD-----I 945
Cdd:PRK02224  575 AELNSKLAELKERIESL------ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEfdearI 648

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 386767616  946 RRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAhyavELEKMRDRYE 1002
Cdd:PRK02224  649 EEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELE----ELEELRERRE 701
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
677-1233 9.13e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.45  E-value: 9.13e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  677 GEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQAtlgksqlqHEKLqNSLDKAQNEVDHLQDKLDKacten 756
Cdd:PRK02224  162 GKLEEYRERASDARLGVERVLSDQRGSLDQLKAQIEEKEEKDL--------HERL-NGLESELAELDEEIERYEE----- 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  757 rrlvlEKEKLTYDYDNLQSQLDkalgQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKL 836
Cdd:PRK02224  228 -----QREQARETRDEADEVLE----EHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDL 298

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  837 IDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQ 916
Cdd:PRK02224  299 LAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREA 378

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  917 LSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERV-------TYELERAHAAQTKASASVEAAKEEAAH 989
Cdd:PRK02224  379 VEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELrereaelEATLRTARERVEEAEALLEAGKCPECG 458

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  990 YAVELEKMRDRYEKSQVELRKLQDtdtfgrETRRLKEENERLREKLDktlmeletiRGKSQYESES-FEKYKDKYEKIEM 1068
Cdd:PRK02224  459 QPVEGSPHVETIEEDRERVEELEA------ELEDLEEEVEEVEERLE---------RAEDLVEAEDrIERLEERREDLEE 523

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1069 EVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARD-------KHEKLLKEVDRLRLQQSSVSP--- 1138
Cdd:PRK02224  524 LIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREevaelnsKLAELKERIESLERIRTLLAAiad 603

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1139 -GDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKE-LEKAQMHLAKQQENTESTRIEFERMGAEL 1216
Cdd:PRK02224  604 aEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREdKERAEEYLEQVEEKLDELREERDDLQAEI 683

                         570
                  ....*....|....*..
gi 386767616 1217 GRLHDRLEKAEAEREAL 1233
Cdd:PRK02224  684 GAVENELEELEELRERR 700
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 268-594 1.95e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.23  E-value: 1.95e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   268 QREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILA 347
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   348 MAAKMKTLEEQHQRhIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKktqgtlqtvqernrLTSELTELKDHMD 427
Cdd:TIGR02168  756 LTELEAEIEELEER-LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE--------------LRAELTLLNEEAA 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   428 IKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEEr 507
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL- 899

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   508 dlhEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSEL-GKSKAELEKATCEMGRSSADWESTKQRIAR 586
Cdd:TIGR02168  900 ---SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKR 976


                   ....*...
gi 386767616   587 LELENERL 594
Cdd:TIGR02168  977 LENKIKEL 984
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 757-1117 2.04e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 2.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   757 RRLVLEKEKLTYDYDnlqSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYAsqkL 836
Cdd:TIGR02169  155 RRKIIDEIAGVAEFD---RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYE---L 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   837 IDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAErsglaaSKAREDLRKLQDESTRLQEACDRAALQ 916
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE------ELNKKIKDLGEEEQLRVKEKIGELEAE 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   917 LSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEK 996
Cdd:TIGR02169  303 IASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   997 MRDRYEKSQVELRKLQDT-DTFGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMES 1075
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREiNELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAA 462

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 386767616  1076 KLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARD 1117
Cdd:TIGR02169  463 DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 265-1070 2.32e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 2.32e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   265 DHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQE 344
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKR 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   345 ILAMAAKMKTLEEQHQRhiavlkeslcAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKD 424
Cdd:TIGR02169  267 LEEIEQLLEELNKKIKD----------LGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   425 HMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQ 504
Cdd:TIGR02169  337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQ 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   505 EERDlherEVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRI 584
Cdd:TIGR02169  417 RLSE----ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQREL 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   585 ARLELENERLKHDLERSQTTFGRTTMTTS------QELDRAQER-----------------------ADKASAELRRTQA 635
Cdd:TIGR02169  493 AEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvAQLGSVGERyataievaagnrlnnvvveddavAKEAIELLKRRKA 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   636 ---------ELRVTQSDAERAREEAA--------ALQEKLEKSQGEVYRLKAKLENAQGEQE--------SLRQELEKAQ 690
Cdd:TIGR02169  573 gratflplnKMRDERRDLSILSEDGVigfavdlvEFDPKYEPAFKYVFGDTLVVEDIEAARRlmgkyrmvTLEGELFEKS 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   691 SGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRlvlekekltydy 770
Cdd:TIGR02169  653 GAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGE------------ 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   771 dnLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLidEKDTSNKEFEKM 850
Cdd:TIGR02169  721 --IEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL--EARLSHSRIPEI 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   851 LEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSE 930
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   931 LEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYavELEKMRDRYEKSQV-ELR 1009
Cdd:TIGR02169  877 LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI--EDPKGEDEEIPEEElSLE 954

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 386767616  1010 KLQDT-DTFGRETRRLKEENERLREKLD---KTLMELETIRGKSQYESESFEKYKDKYEKIEMEV 1070
Cdd:TIGR02169  955 DVQAElQRVEEEIRALEPVNMLAIQEYEevlKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 284-813 2.74e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 2.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  284 RVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQRH- 362
Cdd:COG1196   236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELe 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  363 --IAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKI 440
Cdd:COG1196   316 erLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  441 ENLEDLLKEKDNQVDMARARLSAMQAhhsssegALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIK 520
Cdd:COG1196   396 AELAAQLEELEEAEEALLERLERLEE-------ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  521 LRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGR------SSADWESTKQRIARLELENERL 594
Cdd:COG1196   469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglagavAVLIGVEAAYEAALEAALAAAL 548

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  595 KHDLERSQTTFGRTTMTTSQE---------LDRAQERADKASAELRRTQAELRVT-QSDAERAREEAAALQEKLEKSQGE 664
Cdd:COG1196   549 QNIVVEDDEVAAAAIEYLKAAkagratflpLDKIRARAALAAALARGAIGAAVDLvASDLREADARYYVLGDTLLGRTLV 628

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  665 VYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDH 744
Cdd:COG1196   629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386767616  745 LQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERD 813
Cdd:COG1196   709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 201-961 6.55e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 6.55e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   201 KKERALRKEESAKYSL---------INDQLKLLSTENQK----QAMLVRQLEEELRLRMRQPNlEMQQQMEAIYAENDHL 267
Cdd:TIGR02169  171 KKEKALEELEEVEENIerldliideKRQQLERLRREREKaeryQALLKEKREYEGYELLKEKE-ALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   268 QREISILRETIKDLECRVETQKQTLIARDESIKKLlemlqakgmGKEEERQMfqqmqamaQKQLDEFRLEIQRRDQEILA 347
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDL---------GEEEQLRV--------KEKIGELEAEIASLERSIAE 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   348 MAAKMKTLEEQHQRHIAVLKESLCAKEEhynmLQTDVEEMRARLEE-KNRLIEKKT-----QGTLQTVQERNRLT-SELT 420
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDKLLAEIEE----LEREIEEERKRRDKlTEEYAELKEeledlRAELEEVDKEFAETrDELK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   421 ELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAE 500
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   501 hekQEERDLHErEVADYKIKLRAAESEVEKLQTR---LERAVTERERLEIKLEASQ-------SELGKSKAELEKAtCEM 570
Cdd:TIGR02169  469 ---QELYDLKE-EYDRVEKELSKLQRELAEAEAQaraSEERVRGGRAVEEVLKASIqgvhgtvAQLGSVGERYATA-IEV 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   571 GRSSA------DWESTKQ--------------------RIARLELENERLKHD--------------------------- 597
Cdd:TIGR02169  544 AAGNRlnnvvvEDDAVAKeaiellkrrkagratflplnKMRDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdt 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   598 -------------------------LERSQTTFGRTTMTTSQELDRAQERAD--KASAELRRTQAELRVTQSDAERAREE 650
Cdd:TIGR02169  624 lvvedieaarrlmgkyrmvtlegelFEKSGAMTGGSRAPRGGILFSRSEPAElqRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   651 AAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEK 730
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALND 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   731 LQNSLdkAQNEVDHLQDKLDKACTENRRLV--------------LEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSL 796
Cdd:TIGR02169  784 LEARL--SHSRIPEIQAELSKLEEEVSRIEarlreieqklnrltLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNG 861

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   797 DTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNkefekmlEKYDRAQNEIYRLQSRCDTAEADRA 876
Cdd:TIGR02169  862 KKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE-------AQIEKKRKRLSELKAKLEALEEELS 934

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   877 RLEvEAERSGLAASKAREDLRKLQDESTRLQEAcdraalqLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQ 956
Cdd:TIGR02169  935 EIE-DPKGEDEEIPEEELSLEDVQAELQRVEEE-------IRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006


                   ....*
gi 386767616   957 SELER 961
Cdd:TIGR02169 1007 ERIEE 1011
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 255-961 1.98e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 62.93  E-value: 1.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   255 QQMEAIYAENDHLQR------EISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQ 328
Cdd:pfam12128  221 QQVEHWIRDIQAIAGimkirpEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWK 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   329 KQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQRHIAVLKESLCAKEEHYNMLQTDVEEMRAR---LEEKNRLIEKKTQGT 405
Cdd:pfam12128  301 EKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERlkaLTGKHQDVTAKYNRR 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   406 LQTVQERNRltseltelkdhmdikdRKISVLQRKIENledllkekdnqvdmararlsamqahhsSSEGALTSLEEAIGDK 485
Cdd:pfam12128  381 RSKIKEQNN----------------RDIAGIKDKLAK---------------------------IREARDRQLAVAEDDL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   486 EKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKL------QTRLERAVTERERLEIKLEASQSELGKS 559
Cdd:pfam12128  418 QALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLlqlenfDERIERAREEQEAANAEVERLQSELRQA 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   560 KAELEKATCEMGRSSADWESTKQRIARLELENERLKHDL-ERSQTTFGRTTMTTSQELDRAQ-ERAD--------KASAE 629
Cdd:pfam12128  498 RKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLlHFLRKEAPDWEQSIGKVISPELlHRTDldpevwdgSVGGE 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   630 LRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEK 709
Cdd:pfam12128  578 LNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRR 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   710 IKEEMERTQATLGKSQLQHEKLQ----NSLDKAQNEVDHlQDKLDKACTENRRLVLEKEKLTY------DYDNLQSQLDK 779
Cdd:pfam12128  658 LFDEKQSEKDKKNKALAERKDSAnerlNSLEAQLKQLDK-KHQAWLEEQKEQKREARTEKQAYwqvvegALDAQLALLKA 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   780 ALgQAARMQKERETLSLDTDRIRE--KLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRA 857
Cdd:pfam12128  737 AI-AARRSGAKAELKALETWYKRDlaSLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQ 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   858 QNEIYRLQSRCDtaeADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSrDR 937
Cdd:pfam12128  816 LSNIERAISELQ---QQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIG-ER 891

                          730       740
                   ....*....|....*....|....
gi 386767616   938 FDKLQTDIRRAQGEKEHFQSELER 961
Cdd:pfam12128  892 LAQLEDLKLKRDYLSESVKKYVEH 915
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 384-818 2.57e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 2.57e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   384 VEEMRARLEEKNRliekktqgtlqtvqERNRLTSELTELKDHMDIKDRKISVLQRKIENLEdllkekdnqvdmarARLSA 463
Cdd:TIGR02169  676 LQRLRERLEGLKR--------------ELSSLQSELRRIENRLDELSQELSDASRKIGEIE--------------KEIEQ 727

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   464 MQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQE-ERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTER 542
Cdd:TIGR02169  728 LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEElEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEV 807

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   543 ERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLErsqttfgrttmttsqeldraqer 622
Cdd:TIGR02169  808 SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE----------------------- 864

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   623 adKASAELRRTQAELRvtqsdaerareeaaALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDR 702
Cdd:TIGR02169  865 --ELEEELEELEAALR--------------DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   703 AFSEVEKIKEEMERTQATLGKSQlqheklqnSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKalg 782
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPEEEL--------SLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAK--- 997

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 386767616   783 qaarMQKERETLSLDTDRIREKLEKTQMERDDAVTE 818
Cdd:TIGR02169  998 ----LEEERKAILERIEEYEKKKREVFMEAFEAINE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 891-1678 3.68e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 3.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   891 KAREDLRKLQDESTRLQEACDRAALQLSRAKECED--NARSELEHS---------RDRFDKLQTDIRRAQGEKEHFQSEL 959
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLERQAEKAERYKElkAELRELELAllvlrleelREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   960 ERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQdtdtfgRETRRLKEENERLREKLDKTL 1039
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE------RQLEELEAQLEELESKLDELA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1040 MELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIE-------R 1112
Cdd:TIGR02168  337 EELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARlerledrR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1113 EKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIdRLRDRLEKALQSRDATELEAGRLAKELEKAQ 1192
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE-ELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1193 MHLAKQQENTESTRIEF---ERMGAELGRLHDRLEkAEAEREALRQANRSGGAGAAPHPQLEKHVQKLESDVKQLAMERE 1269
Cdd:TIGR02168  496 RLQENLEGFSEGVKALLknqSGLSGILGVLSELIS-VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVT 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1270 QLVLQLEKSQEILMNFQKELQNAE------AELQKTREENRKLRNG-----HQVPPVAAPPAGPSPAEFQAMqkeIQTLQ 1338
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDREILKNIEgflgvaKDLVKFDPKLRKALSYllggvLVVDDLDNALELAKKLRPGYR---IVTLD 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1339 QKLQeseRALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQM 1418
Cdd:TIGR02168  652 GDLV---RPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1419 QQQQQAAQQAVqqaaqqqqsaagaggadpKELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQ 1498
Cdd:TIGR02168  729 SALRKDLARLE------------------AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1499 VQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEE 1578
Cdd:TIGR02168  791 IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1579 KEKKMAEFDVQLRKRKEQMDQLEKSLQTQgggAAAAGELNKKLMDTQRQLEAC---VKELQNTKEEHK-KAATETERLLQ 1654
Cdd:TIGR02168  871 LESELEALLNERASLEEALALLRSELEEL---SEELRELESKRSELRRELEELrekLAQLELRLEGLEvRIDNLQERLSE 947

                          810       820
                   ....*....|....*....|....
gi 386767616  1655 LVQMSQEEQNAKEKTIMDLQQALK 1678
Cdd:TIGR02168  948 EYSLTLEEAEALENKIEDDEEEAR 971
PTZ00121 PTZ00121
MAEBL; Provisional
 261-1067 5.74e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 5.74e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  261 YAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKgmgkEEERQMFQQMQAMAQKQLDEFRLEIQR 340
Cdd:PTZ00121 1076 YKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKA----EDARKAEEARKAEDARKAEEARKAEDA 1151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  341 RDQEILAMAAKMKTLEEQHQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSElt 420
Cdd:PTZ00121 1152 KRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAV-- 1229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  421 elkdhmdikdRKISVLQRKIENLEDLLKEKDNQvdMARARLSAMQAHHSSSEGALTSlEEAIGDKEKQMAQLRDQRDRAE 500
Cdd:PTZ00121 1230 ----------KKAEEAKKDAEEAKKAEEERNNE--EIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKADEAK 1296

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  501 HEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKAtcemgrssadweST 580
Cdd:PTZ00121 1297 KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA------------EE 1364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  581 KQRIARLELENERLKHDlersQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRvtQSDAERAREEAAALQEKLEK 660
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKAD----AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK--KADEAKKKAEEKKKADEAKK 1438

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  661 SQGEVYR---LKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQlqheklqnsldK 737
Cdd:PTZ00121 1439 KAEEAKKadeAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAA-----------E 1507

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  738 AQNEVDHLQDKLDKACTENRRLVLEKEKLtydyDNLQSQLDKAlgQAARMQKERETLSLDTDRIREKLEKTQMERDDAVT 817
Cdd:PTZ00121 1508 AKKKADEAKKAEEAKKADEAKKAEEAKKA----DEAKKAEEKK--KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALR 1581

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  818 EVEILKEKLDKALYASQKLIDEKDTSNKEFEKmlekydraqneiyrlqsrcdtaEADRARLEVEAERSGLAASKAREDLR 897
Cdd:PTZ00121 1582 KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK----------------------KAEEAKIKAEELKKAEEEKKKVEQLK 1639

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  898 KLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQgEKEHFQSELERVTYELERAHAAQTKAS 977
Cdd:PTZ00121 1640 KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA-EALKKEAEEAKKAEELKKKEAEEKKKA 1718

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  978 ASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFE 1057
Cdd:PTZ00121 1719 EELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798

                         810
                  ....*....|
gi 386767616 1058 KYKDKYEKIE 1067
Cdd:PTZ00121 1799 KIKDIFDNFA 1808
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 217-741 6.79e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 60.90  E-value: 6.79e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   217 INDQLKLLSTENQ-KQAMLVRQLEEELRLRMRQPNLEM-----------------QQQMEAIYAE----NDHLQREISIL 274
Cdd:pfam15921  243 VEDQLEALKSESQnKIELLLQQHQDRIEQLISEHEVEItgltekassarsqansiQSQLEIIQEQarnqNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   275 RETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKT 354
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKR 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   355 LEEQHQRH---IAVLKESLCAKEEHYNML-----------QTDVEEMRARLEEKNRLIEKKTQGTLQ---TVQERNRLTS 417
Cdd:pfam15921  403 LWDRDTGNsitIDHLRRELDDRNMEVQRLeallkamksecQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   418 ELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARAR--LSAMQAHHSSSEG--------ALTSLEEAIGDKEK 487
Cdd:pfam15921  483 ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRvdLKLQELQHLKNEGdhlrnvqtECEALKLQMAEKDK 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   488 ----------QMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRaaesEVEKLQTRLERAVTErerleikLEASQSELG 557
Cdd:pfam15921  563 vieilrqqieNMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ----EFKILKDKKDAKIRE-------LEARVSDLE 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   558 KSKAELEKATCEMGRSSADWESTKQRI------ARLELENerLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELR 631
Cdd:pfam15921  632 LEKVKLVNAGSERLRAVKDIKQERDQLlnevktSRNELNS--LSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   632 RTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLE-------NAQGEQESLRQELEKAQSGVSRIHADRDRAF 704
Cdd:pfam15921  710 QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQfleeamtNANKEKHFLKEEKNKLSQELSTVATEKNKMA 789

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 386767616   705 SEVE-------KIKEEMERTQATLGKSQLQHEKLQNSLDKAQNE 741
Cdd:pfam15921  790 GELEvlrsqerRLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
475-1041 1.08e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.31  E-value: 1.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  475 LTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQS 554
Cdd:COG4913   237 LERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEA 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  555 ELGKSKAELEKATCEM-GRSSADWESTKQRIARLELENERLKHDLERSQttfgrttmttsQELDRAQERADKASAELRRT 633
Cdd:COG4913   317 RLDALREELDELEAQIrGNGGDRLEQLEREIERLERELEERERRRARLE-----------ALLAALGLPLPASAEEFAAL 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  634 QAELRvtqsdaerarEEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHAdrdrafsEVEKIKEE 713
Cdd:COG4913   386 RAEAA----------ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPA-------RLLALRDA 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  714 MERtQATLGKSQLQ-----------HEKLQNSLDKAQN--------EVDHLQDKLdkACTENRRLvleKEKLTYDydnlq 774
Cdd:COG4913   449 LAE-ALGLDEAELPfvgelievrpeEERWRGAIERVLGgfaltllvPPEHYAAAL--RWVNRLHL---RGRLVYE----- 517

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  775 sqldkalgQAARMQKERETLSLDTDRIREKLE----------KTQMERDDAVTEVEILKE--KLDKAL------YASQKL 836
Cdd:COG4913   518 --------RVRTGLPDPERPRLDPDSLAGKLDfkphpfrawlEAELGRRFDYVCVDSPEElrRHPRAItragqvKGNGTR 589

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  837 iDEKDTSNKEFEKML------EKYDRAQNEIYRLQSRCDTAEADRARLEVEAErsglAASKAREDLRKLQDESTRLQ--E 908
Cdd:COG4913   590 -HEKDDRRRIRSRYVlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELD----ALQERREALQRLAEYSWDEIdvA 664

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  909 ACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAA-KEEA 987
Cdd:COG4913   665 SAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAeDLAR 744

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 386767616  988 AHYAVELEKMRDRYEKSQVELRKLQDtdtFGRETRRLKEENERLREKLDKTLME 1041
Cdd:COG4913   745 LELRALLEERFAAALGDAVERELREN---LEERIDALRARLNRAEEELERAMRA 795
PTZ00121 PTZ00121
MAEBL; Provisional
 197-819 1.67e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.77  E-value: 1.67e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  197 SPELKKERALRKEESAKyslindqlkllSTENQKQAMLVRQLEEELRLR-MRQPNLEMQQQMEAIYAENDHLQREISILR 275
Cdd:PTZ00121 1190 AEELRKAEDARKAEAAR-----------KAEEERKAEEARKAEDAKKAEaVKKAEEAKKDAEEAKKAEEERNNEEIRKFE 1258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  276 ETIKDLECRVETQKQTLIARD-ESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKT 354
Cdd:PTZ00121 1259 EARMAHFARRQAAIKAEEARKaDELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKA 1338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  355 LEEQHQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMdikdRKIS 434
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL----KKAA 1414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  435 VLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREV 514
Cdd:PTZ00121 1415 AAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEE 1494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  515 ADYKIKLRAAESEVEKLQTRLERAVTERERLEIKL--EASQSELGKSKAELEKATcEMGRSSADWESTKQRIARLELENE 592
Cdd:PTZ00121 1495 AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaeEAKKADEAKKAEEKKKAD-ELKKAEELKKAEEKKKAEEAKKAE 1573

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  593 RLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELR-----VTQSDAERAREEAAALQEKLEKSQGEVYR 667
Cdd:PTZ00121 1574 EDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKikaeeLKKAEEEKKKVEQLKKKEAEEKKKAEELK 1653

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  668 LKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQD 747
Cdd:PTZ00121 1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAE 1733

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386767616  748 KLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSldTDRIREKLEKTQMERDDAVTEV 819
Cdd:PTZ00121 1734 EAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI--EEELDEEDEKRRMEVDKKIKDI 1803
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1062-1637 2.45e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 2.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1062 KYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQssvspgDP 1141
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI------AR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1142 VRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHD 1221
Cdd:COG1196   307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1222 RLEKAEAEREALRQANRsggagaaphpQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTRE 1301
Cdd:COG1196   387 ELLEALRAAAELAAQLE----------ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1302 ENRKLRnghqvppvaaPPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASRE--EIEQWRKVIEQE 1379
Cdd:COG1196   457 EEEALL----------ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAalLLAGLRGLAGAV 526

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1380 KSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQA 1459
Cdd:COG1196   527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS 606

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1460 ACTERDRFQQQLELLVTElekskmSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQK 1539
Cdd:COG1196   607 DLREADARYYVLGDTLLG------RTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1540 QLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMDQLEKSLQTQGGGAAAAGELNK 1619
Cdd:COG1196   681 LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760

                         570
                  ....*....|....*...
gi 386767616 1620 KLMDTQRQLeacvKELQN 1637
Cdd:COG1196   761 DLEELEREL----ERLER 774
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
429-963 6.02e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.77  E-value: 6.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  429 KDRKISVLqRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERD 508
Cdd:PRK03918  199 EKELEEVL-REINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEE 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  509 LHEREVADYKIKLRAAE-SEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARL 587
Cdd:PRK03918  278 LEEKVKELKELKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  588 E---LENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGE 664
Cdd:PRK03918  358 EerhELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGK 437

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  665 VYRLKAKLenaqgEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQ--LQHEKLQNSLDKAQNEV 742
Cdd:PRK03918  438 CPVCGREL-----TEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESelIKLKELAEQLKELEEKL 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  743 D-HLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKalgqAARMQKERETLSLDTDRIREKLEKTQME-RDDAVTEVE 820
Cdd:PRK03918  513 KkYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK----LEELKKKLAELEKKLDELEEELAELLKElEELGFESVE 588

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  821 ILKEKLDKALYASQKLIDEKDtSNKEFEKMLEKYDRAQNEIyrLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQ 900
Cdd:PRK03918  589 ELEERLKELEPFYNEYLELKD-AEKELEREEKELKKLEEEL--DKAFEELAETEKRLEELRKELEELEKKYSEEEYEELR 665

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 386767616  901 DESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKlqtdIRRAQGEKEHFQSELERVT 963
Cdd:PRK03918  666 EEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE----REKAKKELEKLEKALERVE 724
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 396-1235 6.84e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 57.67  E-value: 6.84e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   396 RLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGAL 475
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   476 T----SLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEA 551
Cdd:pfam02463  249 EqeeiESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   552 SQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELR 631
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   632 RTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIK 711
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLEL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   712 EEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLdkacTENRRLVLEKEKLTYDYDNLqsqldkalgqAARMQKER 791
Cdd:pfam02463  489 LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIIS----AHGRLGDLGVAVENYKVAIS----------TAVIVEVS 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   792 ETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTA 871
Cdd:pfam02463  555 ATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   872 EADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNArsELEHSRDRFDKLQTDIRRAQGE 951
Cdd:pfam02463  635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELA--KEEILRRQLEIKKKEQREKEEL 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   952 KEHFQSELERvtyELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERL 1031
Cdd:pfam02463  713 KKLKLEAEEL---LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVE 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1032 REKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIE 1111
Cdd:pfam02463  790 EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1112 REKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKA 1191
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 386767616  1192 QMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQ 1235
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKD 993
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 998-1578 1.13e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  998 RDRYEKSQVELRKLQDtdtfgretRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKL 1077
Cdd:COG1196   219 KEELKELEAELLLLKL--------RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1078 HETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVspgDPVRASTSSSSALSAGER 1157
Cdd:COG1196   291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA---EEELEEAEAELAEAEEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1158 QEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRiefERMGAELGRLHDRLEKAEAEREALRQAN 1237
Cdd:COG1196   368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL---ERLEEELEELEEALAELEEEEEEEEEAL 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1238 RSGGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRKLRNGHQVPPVAA 1317
Cdd:COG1196   445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1318 PPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASREEIeqwrkvIEQEKSRADMADKAAQEMHKRI 1397
Cdd:COG1196   525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF------LPLDKIRARAALAAALARGAIG 598

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1398 QLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRFQQQLELLVTE 1477
Cdd:COG1196   599 AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1478 LEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEvRKQIDNQAKATEG 1557
Cdd:COG1196   679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE-EELLEEEALEELP 757

                         570       580
                  ....*....|....*....|.
gi 386767616 1558 ERKIIDEQRKQIDAKRKDIEE 1578
Cdd:COG1196   758 EPPDLEELERELERLEREIEA 778
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 615-1382 2.49e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.84  E-value: 2.49e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   615 ELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQ----GEVYRLKAKLENAQGEQESLRQELEKAQ 690
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGyellKEKEALERQKEAIERQLASLEEELEKLT 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   691 SGVS----RIHADRDRAFSEVEKIK----EEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLE 762
Cdd:TIGR02169  258 EEISelekRLEEIEQLLEELNKKIKdlgeEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   763 KEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDT 842
Cdd:TIGR02169  338 IEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   843 SNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKE 922
Cdd:TIGR02169  418 LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEA 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   923 CEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKAsasVEAAKEEAAHYAVELEKMRDRYE 1002
Cdd:TIGR02169  498 QARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNN---VVVEDDAVAKEAIELLKRRKAGR 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1003 KSQVELRKLQDtdtFGRETRRLKEENerlrekldKTLMELETIRGKSQYESESFEKYKDKyekieMEVQNMES-KLHETS 1081
Cdd:TIGR02169  575 ATFLPLNKMRD---ERRDLSILSEDG--------VIGFAVDLVEFDPKYEPAFKYVFGDT-----LVVEDIEAaRRLMGK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1082 LQLELSKGEVakmlanqekqrselerahierekardkhekllkevdrlrLQQSSVSPGDPVRASTSSSSALSagERQEID 1161
Cdd:TIGR02169  639 YRMVTLEGEL---------------------------------------FEKSGAMTGGSRAPRGGILFSRS--EPAELQ 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1162 RLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSgg 1241
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN-- 755

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1242 agaaphpqLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMnfQKELQNAEAELQKTREENRKLRnghQVPPVAAPPAG 1321
Cdd:TIGR02169  756 --------VKSELKELEARIEELEEDLHKLEEALNDLEARLS--HSRIPEIQAELSKLEEEVSRIE---ARLREIEQKLN 822

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767616  1322 PSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSR 1382
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 163-840 2.89e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 55.50  E-value: 2.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   163 QNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLEEEL 242
Cdd:pfam05483  123 QELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEEL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   243 RLRMRQPNLEMQQQMEAIYAENDHLQREisiLRETIKDLECRVETQKQTLIARDESIKK---LLEMLQAKGMGKEEERQM 319
Cdd:pfam05483  203 RVQAENARLEMHFKLKEDHEKIQHLEEE---YKKEINDKEKQVSLLLIQITEKENKMKDltfLLEESRDKANQLEEKTKL 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   320 FQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQrhiaVLKESLCAKeehynmlqtdVEEMRARLEEKNRlie 399
Cdd:pfam05483  280 QDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQ----IATKTICQL----------TEEKEAQMEELNK--- 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   400 kktqgtlqtvqERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLE 479
Cdd:pfam05483  343 -----------AKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELK 411

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   480 EAIGDKEKQMAQLRDQRDRAEHEKQEERDL------HEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQ 553
Cdd:pfam05483  412 KILAEDEKLLDEKKQFEKIAEELKGKEQELifllqaREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELT 491

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   554 SELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRT 633
Cdd:pfam05483  492 AHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKS 571

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   634 QAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEE 713
Cdd:pfam05483  572 EENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQK 651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   714 MERTQATLGKS----QLQHEKLQNSLDKAQNEVDH---LQDKLDKACTEN-RRLVLEKEKLTYDYDNLQSQLDKALGQAA 785
Cdd:pfam05483  652 FEEIIDNYQKEiedkKISEEKLLEEVEKAKAIADEavkLQKEIDKRCQHKiAEMVALMEKHKHQYDKIIEERDSELGLYK 731

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 386767616   786 RMQKERETL--SLDTDRIREKLEKTQMERDDAVTEVEilKEKLDKALYASQKLIDEK 840
Cdd:pfam05483  732 NKEQEQSSAkaALEIELSNIKAELLSLKKQLEIEKEE--KEKLKMEAKENTAILKDK 786
PTZ00121 PTZ00121
MAEBL; Provisional
 944-1678 4.10e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 4.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  944 DIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRR 1023
Cdd:PTZ00121 1086 DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARK 1165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1024 LKEENERLREKLDKTLMELETIRgksqyESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRS 1103
Cdd:PTZ00121 1166 AEEARKAEDAKKAEAARKAEEVR-----KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAE 1240

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1104 ELERAHIEREKARDKHEKLLKEVDRLRLQQSSVS----PGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATEL 1179
Cdd:PTZ00121 1241 EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAeearKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEA 1320

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1180 EagrlaKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLEs 1259
Cdd:PTZ00121 1321 K-----KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD- 1394

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1260 DVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEA-----ELQKTREENRKlrnGHQVPPVAAPPAGPSPAEFQAMQKEI 1334
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkkkadEAKKKAEEAKK---ADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1335 QTLQQKLQESERALQAAGPQQAQAAAAAGASREEIEQWRKVIE----QEKSRADMADKAaqEMHKRIQLMDQHIKDQHAQ 1410
Cdd:PTZ00121 1472 ADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEakkaEEAKKADEAKKA--EEAKKADEAKKAEEKKKAD 1549

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1411 MQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRFQQQLELLVTELEKSKmsnQEQAK 1490
Cdd:PTZ00121 1550 ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK---AEELK 1626

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1491 QLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQID 1570
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE 1706

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1571 AKRKDIEEKekkmaefdvqlrKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAATETE 1650
Cdd:PTZ00121 1707 LKKKEAEEK------------KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIR 1774

                         730       740
                  ....*....|....*....|....*...
gi 386767616 1651 RLLQLVqMSQEEQNAKEKTIMDLQQALK 1678
Cdd:PTZ00121 1775 KEKEAV-IEEELDEEDEKRRMEVDKKIK 1801
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 213-950 5.36e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 5.36e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   213 KYSLINDQLKLLSTENQKQAMLvrqleeELRLRMRQPNLEMQQQMEAIYAEndhLQREISILRETIKDLECRVETQKQTL 292
Cdd:pfam15921  109 RQSVIDLQTKLQEMQMERDAMA------DIRRRESQSQEDLRNQLQNTVHE---LEAAKCLKEDMLEDSNTQIEQLRKMM 179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   293 IARDESIKKLLEML----QAKGMGKEEERQM----FQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQRHIA 364
Cdd:pfam15921  180 LSHEGVLQEIRSILvdfeEASGKKIYEHDSMstmhFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIE 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   365 VLkesLCAKEEHYNMLQTDVEEMRARLEEKN---RLIEKKTQGTLQTVQE--RNRLTSELTELKDHMDIKDRKISVLQRK 439
Cdd:pfam15921  260 LL---LQQHQDRIEQLISEHEVEITGLTEKAssaRSQANSIQSQLEIIQEqaRNQNSMYMRQLSDLESTVSQLRSELREA 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   440 IENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIgdkEKQMAQLRDQRDRAEHEKQEERDLHEREVADyki 519
Cdd:pfam15921  337 KRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQL---QKLLADLHKREKELSLEKEQNKRLWDRDTGN--- 410

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   520 klraaESEVEKLQTRLERAVTERERLEIKLEASQSElgkSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLE 599
Cdd:pfam15921  411 -----SITIDHLRRELDDRNMEVQRLEALLKAMKSE---CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVE 482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   600 RSQTTFGRTTMTTSQELDRAQERADKASAeLRRTQAELRVTQSDAERAREEAAALQ---EKLEKSQGEVYRLKAKLENAQ 676
Cdd:pfam15921  483 ELTAKKMTLESSERTVSDLTASLQEKERA-IEATNAEITKLRSRVDLKLQELQHLKnegDHLRNVQTECEALKLQMAEKD 561

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   677 GEQESLRQELEKAQSGVSRihADRDRAFSEVEKIKEEMErtqatLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTEN 756
Cdd:pfam15921  562 KVIEILRQQIENMTQLVGQ--HGRTAGAMQVEKAQLEKE-----INDRRLELQEFKILKDKKDAKIRELEARVSDLELEK 634

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   757 RRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIR-------EKLEKT----QMERDDAVTEVEILKEK 825
Cdd:pfam15921  635 VKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKrnfrnksEEMETTtnklKMQLKSAQSELEQTRNT 714

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   826 LD----------KALYASQKLIDEK----DTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASK 891
Cdd:pfam15921  715 LKsmegsdghamKVAMGMQKQITAKrgqiDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEV 794

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 386767616   892 AREDLRKLQDESTRLQEACDRAALQLSrakECEDNARSELEHSRDRFDKLQTDIRRAQG 950
Cdd:pfam15921  795 LRSQERRLKEKVANMEVALDKASLQFA---ECQDIIQRQEQESVRLKLQHTLDVKELQG 850
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
672-1237 6.77e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.54  E-value: 6.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  672 LENAQGEQESLRQELEKAQSGVSRIHADRDRAfsEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDK 751
Cdd:COG4913   257 IRELAERYAAARERLAELEYLRAALRLWFAQR--RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  752 ACTEnrrlvlEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALY 831
Cdd:COG4913   335 NGGD------RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALA 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  832 ASQKlidekdtsnkEFEKMLEKYDRAQNEIYRLQSRCDT--AEADRARLEVEAersglAASKAREDLR------KLQDES 903
Cdd:COG4913   409 EAEA----------ALRDLRRELRELEAEIASLERRKSNipARLLALRDALAE-----ALGLDEAELPfvgeliEVRPEE 473

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  904 TRLQEACDRA----ALQLSRAKECEDNARSELEHSRDR----FDKLQTDIRRAQGEKEHFQSELERVTYELERAHA---- 971
Cdd:COG4913   474 ERWRGAIERVlggfALTLLVPPEHYAAALRWVNRLHLRgrlvYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwlea 553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  972 --AQTKASASVEAAKE-EAAHYAVELEKM----RDRYEKsqvELRKLQDTD-TFGRETRRLKEENERLREKLDKTLMELE 1043
Cdd:COG4913   554 elGRRFDYVCVDSPEElRRHPRAITRAGQvkgnGTRHEK---DDRRRIRSRyVLGFDNRAKLAALEAELAELEEELAEAE 630

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1044 TIRGKSQYESESFEKYKDKYEKIE---------MEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREK 1114
Cdd:COG4913   631 ERLEALEAELDALQERREALQRLAeyswdeidvASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDE 710

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1115 ARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQ----EIDRLRDRLEKALQSR-DATELEAGRLAKELE 1189
Cdd:COG4913   711 LKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERfaaaLGDAVERELRENLEERiDALRARLNRAEEELE 790

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 386767616 1190 KAQM-HLAKQQENTESTRIEFERMG---AELGRL-HDRLEKAEAE-REALRQAN 1237
Cdd:COG4913   791 RAMRaFNREWPAETADLDADLESLPeylALLDRLeEDGLPEYEERfKELLNENS 844
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 445-1135 8.59e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.07  E-value: 8.59e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   445 DLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIgdkEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAA 524
Cdd:pfam12128  244 TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEER---QETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKD 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   525 ESEVEKLQTRLERavTERERLEiKLEASQSELGKSKAELEkatcEMGRSSADWESTKQRI-----ARLELENERLKHDLE 599
Cdd:pfam12128  321 RSELEALEDQHGA--FLDADIE-TAAADQEQLPSWQSELE----NLEERLKALTGKHQDVtakynRRRSKIKEQNNRDIA 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   600 RSQTTFGRTTMTTSQELDRAQERADKASAELRrTQAELRVTQSDAERAREEAAALQEKLEKSQGEVY-RLKAKLENAQGE 678
Cdd:pfam12128  394 GIKDKLAKIREARDRQLAVAEDDLQALESELR-EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATpELLLQLENFDER 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   679 QESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRR 758
Cdd:pfam12128  473 IERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIG 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   759 LVLEKEKLtydydnLQSQLDKALGQAARMQKER-ETLSLDTDRIreklektqmERDDAVTEVEILKEKLDKALyasqkli 837
Cdd:pfam12128  553 KVISPELL------HRTDLDPEVWDGSVGGELNlYGVKLDLKRI---------DVPEWAASEEELRERLDKAE------- 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   838 dekdtsnkefekmlEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAalqL 917
Cdd:pfam12128  611 --------------EALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKA---L 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   918 SRAKECEDNARSELEHSRDRFDKLQtdirraQGEKEHFQSELervtyeLERAHAAQTKASASVEAAKEEAAHYAVELEKM 997
Cdd:pfam12128  674 AERKDSANERLNSLEAQLKQLDKKH------QAWLEEQKEQK------REARTEKQAYWQVVEGALDAQLALLKAAIAAR 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   998 RDRYEKSQVELRKLQDTDTFGRET-----RRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYekiEMEVQN 1072
Cdd:pfam12128  742 RSGAKAELKALETWYKRDLASLGVdpdviAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRL---ATQLSN 818

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 386767616  1073 MESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSS 1135
Cdd:pfam12128  819 IERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANS 881
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 523-739 1.29e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 1.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  523 AAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQ 602
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  603 TTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQ---EKLEKSQGEVYRLKAKLENAQGEQ 679
Cdd:COG4942    97 AELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARReqaEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  680 ESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQ 739
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 125-546 2.69e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 2.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   125 LEDELYGRSArqspSAMGGYNTGMGPTSDRAYLGDlqhQNTDLQRELGNLKRELELTNQKLgssmHSIKTfwspELKKER 204
Cdd:TIGR02169  644 LEGELFEKSG----AMTGGSRAPRGGILFSRSEPA---ELQRLRERLEGLKRELSSLQSEL----RRIEN----RLDELS 708

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   205 ALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLEEELRlrmrqpnlEMQQQMEAIYAENDHLQREISILRETIKDLECR 284
Cdd:TIGR02169  709 QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS--------SLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   285 VETQKQTLiaRDESIKKLLEMLQAkgmgkeeerqmfqqmqamaqkqLDEFRLEIQRRDQEILAMAAKMKTLEEQHQRHIA 364
Cdd:TIGR02169  781 LNDLEARL--SHSRIPEIQAELSK----------------------LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ 836

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   365 VLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTqgtlqtvQERNRLTSELTELKDHMDIKDRKISVLQRKIENLE 444
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE-------AALRDLESRLGDLKKERDELEAQLRELERKIEELE 909

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   445 DLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEaIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAA 524
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRL 988

                          410       420
                   ....*....|....*....|..
gi 386767616   525 ESEVEKLQTRLERAVTERERLE 546
Cdd:TIGR02169  989 DELKEKRAKLEEERKAILERIE 1010
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
757-1011 3.43e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 3.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  757 RRLVLEKEKLTYDYDNLQSQ---LDKALGQAARMQKERETLSldtdRIREKLEKTQMERDDAvTEVEILKEKLDkaLYAS 833
Cdd:COG4913   214 REYMLEEPDTFEAADALVEHfddLERAHEALEDAREQIELLE----PIRELAERYAAARERL-AELEYLRAALR--LWFA 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  834 QKLIDEKDtsnKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLaaskarEDLRKLQDESTRLQEACDRA 913
Cdd:COG4913   287 QRRLELLE---AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG------DRLEQLEREIERLERELEER 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  914 ALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAqgekehfqseLERVTYELERAHAAQTKASASVEAAKEEAAHYAVE 993
Cdd:COG4913   358 ERRRARLEALLAALGLPLPASAEEFAALRAEAAAL----------LEALEEELEALEEALAEAEAALRDLRRELRELEAE 427

                         250       260
                  ....*....|....*....|.
gi 386767616  994 ---LEKMRDRYEKSQVELRKL 1011
Cdd:COG4913   428 iasLERRKSNIPARLLALRDA 448
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 498-825 5.01e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 51.05  E-value: 5.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   498 RAEHEKQEERDLH-EREVADYKIKLRAAESEVEKLQtrLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSAD 576
Cdd:pfam07888   35 RLEECLQERAELLqAQEAANRQREKEKERYKRDREQ--WERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEE 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   577 WESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRvtqsdaerareeaaALQE 656
Cdd:pfam07888  113 LSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERK--------------QLQA 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   657 KLEKSQGEVYRLKA---KLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQN 733
Cdd:pfam07888  179 KLQQTEEELRSLSKefqELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGE 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   734 SLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDK---ALGQAARMQKER-ETLSLDTDRIREKLEKTQ 809
Cdd:pfam07888  259 ELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQereTLQQSAEADKDRiEKLSAELQRLEERLQEER 338

                          330
                   ....*....|....*.
gi 386767616   810 MERDdaVTEVEILKEK 825
Cdd:pfam07888  339 MERE--KLEVELGREK 352
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 297-1067 1.10e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.49  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   297 ESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTL--EEQHQRHIAVLKESLCAKE 374
Cdd:pfam05483   88 EKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLikENNATRHLCNLLKETCARS 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   375 -EHYNMLQTDVEEMRARLEEKNRLIEKktqgtLQTVQERNRLTSELTELKDHMDIKDRkisvlQRKIENLEDLLKEKDNQ 453
Cdd:pfam05483  168 aEKTKKYEYEREETRQVYMDLNNNIEK-----MILAFEELRVQAENARLEMHFKLKED-----HEKIQHLEEEYKKEIND 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   454 VDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQT 533
Cdd:pfam05483  238 KEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEE 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   534 RLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTkqriarLELENERLKHDlERSQTTFGRTTMTTS 613
Cdd:pfam05483  318 DLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEL------LRTEQQRLEKN-EDQLKIITMELQKKS 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   614 QELDRAQERADKASAELRrtqaELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEkaqsgv 693
Cdd:pfam05483  391 SELEEMTKFKNNKEVELE----ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLT------ 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   694 srihadrdrafseVEKIKEEMERTQATLGKSQLQHEKLQNSldkaqnevdHLQDKLDKACTENRRLVLEKEKLTYDYDNL 773
Cdd:pfam05483  461 -------------AIKTSEEHYLKEVEDLKTELEKEKLKNI---------ELTAHCDKLLLENKELTQEASDMTLELKKH 518

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   774 QSQLDKALGQAARMQKERETLSLDTDRIREKLEktqmerddavteveilkekldkalYASQKLIDEKDTSNKEFEKMLEK 853
Cdd:pfam05483  519 QEDIINCKKQEERMLKQIENLEEKEMNLRDELE------------------------SVREEFIQKGDEVKCKLDKSEEN 574

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   854 YDRAQNEIYRLQSRCDTAEADRARLEVEAERSGlaaskarEDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEH 933
Cdd:pfam05483  575 ARSIEYEVLKKEKQMKILENKCNNLKKQIENKN-------KNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELAS 647

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   934 SRDRFDKLqtdIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQD 1013
Cdd:pfam05483  648 AKQKFEEI---IDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERD 724

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 386767616  1014 TDTFGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIE 1067
Cdd:pfam05483  725 SELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKE 778
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 664-958 1.33e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 49.93  E-value: 1.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  664 EVYRLKAKLENAQ-GEQESLRQELEKaqsgvsriHADRDRAFSEVEKIKEEMERTQATLGKSQLQhEKLQNSLDKAQNEV 742
Cdd:PRK05771   32 HIEDLKEELSNERlRKLRSLLTKLSE--------ALDKLRSYLPKLNPLREEKKKVSVKSLEELI-KDVEEELEKIEKEI 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  743 DHLQDKLDKACTENRRLVLEKEKLTYdYDNLQSQLDKALGqaarmqkeRETLSLDTDRIREKLEKtQMERDDAVTEVEIL 822
Cdd:PRK05771  103 KELEEEISELENEIKELEQEIERLEP-WGNFDLDLSLLLG--------FKYVSVFVGTVPEDKLE-ELKLESDVENVEYI 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  823 KEKLDKALYAsqkLIDEKDTSnKEFEKMLEKYDRAQNEIYrlqsrcDTAEADRARLEVEAERSGLAA--SKAREDLRKLQ 900
Cdd:PRK05771  173 STDKGYVYVV---VVVLKELS-DEVEEELKKLGFERLELE------EEGTPSELIREIKEELEEIEKerESLLEELKELA 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 386767616  901 DESTRLQEACDRAALQLS-RAKECEDNARSELEHS------RDRFDKLQTDIRRAQGEKEHFQSE 958
Cdd:PRK05771  243 KKYLEELLALYEYLEIELeRAEALSKFLKTDKTFAiegwvpEDRVKKLKELIDKATGGSAYVEFV 307
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 456-689 1.59e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  456 MARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAehekQEERDLHEREVADYKIKLRAAESEVEKLQTRL 535
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKAL----LKQLAALERRIAALARRIRALEQELAALEAEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  536 ERAVTERERLEIKLEASQSELgkskAELEKATCEMGR--------SSADWESTKQRIARLELENERLKHDLERsQTTFGR 607
Cdd:COG4942    86 AELEKEIAELRAELEAQKEEL----AELLRALYRLGRqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEE-LRADLA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  608 TTMTTSQELDRAQERADKASAELRRTQAELrvtQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELE 687
Cdd:COG4942   161 ELAALRAELEAERAELEALLAELEEERAAL---EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237


                  ..
gi 386767616  688 KA 689
Cdd:COG4942   238 AA 239
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
613-896 2.73e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 48.36  E-value: 2.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  613 SQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSG 692
Cdd:COG4372    30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEE 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  693 VSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKactenrrlvLEKEKLTYDYDN 772
Cdd:COG4372   110 AEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAA---------LEQELQALSEAE 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  773 LQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLE 852
Cdd:COG4372   181 AEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEI 260

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 386767616  853 KYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDL 896
Cdd:COG4372   261 EELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNL 304
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 590-958 2.79e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 48.74  E-value: 2.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   590 ENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLK 669
Cdd:pfam07888   38 ECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEK 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   670 AKLENAQGEQESLRQELEKAQSGVSRIHADRDrafSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKL 749
Cdd:pfam07888  118 DALLAQRAAHEARIRELEEDIKTLTQRVLERE---TELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEF 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   750 DKActenRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQmerddavTEVEILKEKLdka 829
Cdd:pfam07888  195 QEL----RNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASE-------RKVEGLGEEL--- 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   830 lyasQKLIDEKDTSNKEFEKmlEKYDRAQNEIYRLQSRCDTAEaDRARLEVEAERSGLAASKAREDLRKLQDESTRLQEA 909
Cdd:pfam07888  261 ----SSMAAQRDRTQAELHQ--ARLQAAQLTLQLADASLALRE-GRARWAQERETLQQSAEADKDRIEKLSAELQRLEER 333

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 386767616   910 -----CDRAALQLSRAKEcEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSE 958
Cdd:pfam07888  334 lqeerMEREKLEVELGRE-KDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 270-855 3.19e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.86  E-value: 3.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   270 EISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKG---MGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEIL 346
Cdd:TIGR04523   76 KIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKeqkNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELE 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   347 AMAAKMKTLEEQHQRHIAVLKESLCAKEEHYNMLQtDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHM 426
Cdd:TIGR04523  156 KLNNKYNDLKKQKEELENELNLLEKEKLNIQKNID-KIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNI 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   427 DIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHhsssegaLTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEE 506
Cdd:TIGR04523  235 EKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE-------LEQNNKKIKELEKQLNQLKSEISDLNNQKEQD 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   507 --RDLHErEVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRI 584
Cdd:TIGR04523  308 wnKELKS-ELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEI 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   585 ARLELENERLKHDLErsqttfgrTTMTTSQELDRaqeradkasaelrrtqaELRVTQSDAERAREEAAALQEKLEKSQGE 664
Cdd:TIGR04523  387 KNLESQINDLESKIQ--------NQEKLNQQKDE-----------------QIKKLQQEKELLEKEIERLKETIIKNNSE 441

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   665 VYRLKAK---LENAQGEQESLRQELEKAQSGVSRihadrdrafsEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNE 741
Cdd:TIGR04523  442 IKDLTNQdsvKELIIKNLDNTRESLETQLKVLSR----------SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEK 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   742 VDHLQDKLDKACTENRRLVLEKEKLtydydnlQSQLDkalgqaarmQKERETLSLDTDRIREKLEKTQMERDDAVTEVEI 821
Cdd:TIGR04523  512 VKDLTKKISSLKEKIEKLESEKKEK-------ESKIS---------DLEDELNKDDFELKKENLEKEIDEKNKEIEELKQ 575

                          570       580       590
                   ....*....|....*....|....*....|....
gi 386767616   822 LKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYD 855
Cdd:TIGR04523  576 TQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKE 609
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 873-1274 3.76e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.80  E-value: 3.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  873 ADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRrAQGEK 952
Cdd:COG3096   271 ADYMRHANERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALR-QQEKI 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  953 EHFQSELERVTYELERAHAAqtkasasVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDT-DTfgRETRRLKEENERl 1031
Cdd:COG3096   350 ERYQEDLEELTERLEEQEEV-------VEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQAlDV--QQTRAIQYQQAV- 419

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1032 rekldKTLMELETIRGKSQYESESFEKYkdkyekiEMEVQNMESKLHETSLQLElSKGEVAKMLANQEKQRSELERA--- 1108
Cdd:COG3096   420 -----QALEKARALCGLPDLTPENAEDY-------LAAFRAKEQQATEEVLELE-QKLSVADAARRQFEKAYELVCKiag 486

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1109 HIEREKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKEL 1188
Cdd:COG3096   487 EVERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQL 566

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1189 EKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLESDVKQLAMER 1268
Cdd:COG3096   567 EELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVER 646


                  ....*.
gi 386767616 1269 EQLVLQ 1274
Cdd:COG3096   647 DELAAR 652
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
699-1311 4.36e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 4.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  699 DRDRAFSEVEKIKEEMErtqatlgksqlQHEKLQNSLDKAQNEVDHLQDkLDKACTENRRLVLEKEKLtydydnlqsQLD 778
Cdd:COG4913   219 EEPDTFEAADALVEHFD-----------DLERAHEALEDAREQIELLEP-IRELAERYAAARERLAEL---------EYL 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  779 KALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKAlyasQKLIDEKDTSNKEfekmlekydRAQ 858
Cdd:COG4913   278 RAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEL----EAQIRGNGGDRLE---------QLE 344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  859 NEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRaalQLSRAKECEDNARSELEHSRDRF 938
Cdd:COG4913   345 REIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEE---ELEALEEALAEAEAALRDLRREL 421

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  939 DKLQTDIRRAQGEKEHFQSELERVTYELERAhaaqtkasasvEAAKEEAAHYAVELEKMRDRYEKSQ--VE-------LR 1009
Cdd:COG4913   422 RELEAEIASLERRKSNIPARLLALRDALAEA-----------LGLDEAELPFVGELIEVRPEEERWRgaIErvlggfaLT 490

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1010 KLQDTDTFGRETRRLKEENERLR---EKLDKTLMELETIR-------GKSQYESESFEKYkdkyekIEMEVQNM------ 1073
Cdd:COG4913   491 LLVPPEHYAAALRWVNRLHLRGRlvyERVRTGLPDPERPRldpdslaGKLDFKPHPFRAW------LEAELGRRfdyvcv 564

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1074 ----ESKLHETSLQLE-LSKG---------------------EVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVD 1127
Cdd:COG4913   565 dspeELRRHPRAITRAgQVKGngtrhekddrrrirsryvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQ 644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1128 RLRLQQSSVSpgdpvraSTSSSSALSAGERQEIDRLRDRLEKALQSRDateleagrlakELEKAQMHLAKQQENTESTRI 1207
Cdd:COG4913   645 ERREALQRLA-------EYSWDEIDVASAEREIAELEAELERLDASSD-----------DLAALEEQLEELEAELEELEE 706

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1208 EFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEkhvqkLESDVKQLAMEreqlvlqlEKSQEILMNFQK 1287
Cdd:COG4913   707 ELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL-----LEERFAAALGD--------AVERELRENLEE 773

                         650       660
                  ....*....|....*....|....
gi 386767616 1288 ELQNAEAELQKTREENRKLRNGHQ 1311
Cdd:COG4913   774 RIDALRARLNRAEEELERAMRAFN 797
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
236-715 5.07e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 5.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  236 RQLEEELR-LRMRQPNLE-MQQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMlqakgMGK 313
Cdd:PRK03918  217 PELREELEkLEKEVKELEeLKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-----KEK 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  314 EEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQRhIAVLKESLCAKEEHYNMLQTDVEEMRARLEE 393
Cdd:PRK03918  292 AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEER-LEELKKKLKELEKRLEELEERHELYEEAKAK 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  394 KNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEG 473
Cdd:PRK03918  371 KEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHR 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  474 A---------LTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDL-HEREVADykiKLRAAESEVEKLQT-RLERAVTER 542
Cdd:PRK03918  451 KelleeytaeLKRIEKELKEIEEKERKLRKELRELEKVLKKESELiKLKELAE---QLKELEEKLKKYNLeELEKKAEEY 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  543 ERLEIKLEASQSELGKSKAELEKATCEMGRSsadwESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQER 622
Cdd:PRK03918  528 EKLKEKLIKLKGEIKSLKKELEKLEELKKKL----AELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNE 603

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  623 ---ADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKL-----ENAQGEQESLRQELEKAQSGVS 694
Cdd:PRK03918  604 yleLKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYseeeyEELREEYLELSRELAGLRAELE 683

                         490       500
                  ....*....|....*....|.
gi 386767616  695 RIHADRDRAFSEVEKIKEEME 715
Cdd:PRK03918  684 ELEKRREEIKKTLEKLKEELE 704
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 575-1223 5.47e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 5.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   575 ADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRaQERADKASAELRRTQAELRvtqsdaerareeaAAL 654
Cdd:pfam12128  234 AGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASR-QEERQETSAELNQLLRTLD-------------DQW 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   655 QEKLEKSQGEVYRLKAKLENAQGEQESLR-QELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQN 733
Cdd:pfam12128  300 KEKRDELNGELSAADAAVAKDRSELEALEdQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNR 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   734 --SLDKAQN--EVDHLQDKLDKACTENRRLVLEKEKltyDYDNLQSQLDKALGQA---ARMQKERETLSLDTDRIR---- 802
Cdd:pfam12128  380 rrSKIKEQNnrDIAGIKDKLAKIREARDRQLAVAED---DLQALESELREQLEAGkleFNEEEYRLKSRLGELKLRlnqa 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   803 EKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEAD-------- 874
Cdd:pfam12128  457 TATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlfpqagtl 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   875 RARLEVEA----ERSGLAASKA---REDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSElEHSRDRFDKLQTDIRR 947
Cdd:pfam12128  537 LHFLRKEApdweQSIGKVISPEllhRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASE-EELRERLDKAEEALQS 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   948 AQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTD--TFGRETRRLK 1025
Cdd:pfam12128  616 AREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERlnSLEAQLKQLD 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1026 EENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLEL-----SKGEVAKMLANQEK 1100
Cdd:pfam12128  696 KKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYkrdlaSLGVDPDVIAKLKR 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1101 QRSELERAhIEReKARDKHEKLLKEvdrlRLQQSSVSPGDPVRASTSSSSALSAGE-RQEIDRL----RDRLEKALQSRD 1175
Cdd:pfam12128  776 EIRTLERK-IER-IAVRRQEVLRYF----DWYQETWLQRRPRLATQLSNIERAISElQQQLARLiadtKLRRAKLEMERK 849

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 386767616  1176 ATELEAGRLAKELEK--------AQMHLAKQQENTESTRIEFERMGAELGRLHDRL 1223
Cdd:pfam12128  850 ASEKQQVRLSENLRGlrcemsklATLKEDANSEQAQGSIGERLAQLEDLKLKRDYL 905
PRK01156 PRK01156
chromosome segregation protein; Provisional
 331-883 6.07e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.97  E-value: 6.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  331 LDEFRLEIQRRDQEILAMAAKMKTLEEQHQ---RHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIE--KKTQGT 405
Cdd:PRK01156  185 IDYLEEKLKSSNLELENIKKQIADDEKSHSitlKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESeiKTAESD 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  406 LQTVQERNRLTSELTElkDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMArarlsamqahhSSSEGALTSLEEAIgdk 485
Cdd:PRK01156  265 LSMELEKNNYYKELEE--RHMKIINDPVYKNRNYINDYFKYKNDIENKKQIL-----------SNIDAEINKYHAII--- 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  486 eKQMAQLRDQRDRAEHEKQEERDL-HER-EVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAEL 563
Cdd:PRK01156  329 -KKLSVLQKDYNDYIKKKSRYDDLnNQIlELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAI 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  564 EKATCEMGRS----SADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRV 639
Cdd:PRK01156  408 KKELNEINVKlqdiSSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIRE 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  640 TQSDAERAREEAAALQEKLEKSQGEVYRlkaKLENAQGEQESLRQELEKAQSGVSRIHADRDRAfsevEKIKEEMERTQa 719
Cdd:PRK01156  488 IEIEVKDIDEKIVDLKKRKEYLESEEIN---KSINEYNKIESARADLEDIKIKINELKDKHDKY----EEIKNRYKSLK- 559

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  720 tLGKSQLQHEKLQNSLDKAQN-EVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGqaaRMQKERETLSLDT 798
Cdd:PRK01156  560 -LEDLDSKRTSWLNALAVISLiDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIR---EIENEANNLNNKY 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  799 DRIREKlektqmerddavtevEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARL 878
Cdd:PRK01156  636 NEIQEN---------------KILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARL 700


                  ....*
gi 386767616  879 EVEAE 883
Cdd:PRK01156  701 ESTIE 705
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
252-716 6.26e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 6.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  252 EMQQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLlemlqakgmgkEEERQMFQQMQAMAQKQL 331
Cdd:PRK02224  262 DLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAV-----------EARREELEDRDEELRDRL 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  332 DEFRLEIQRRDQEILAMAAKMKTLEEQHQRhiavLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQE 411
Cdd:PRK02224  331 EECRVAAQAHNEEAESLREDADDLEERAEE----LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD 406

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  412 RNRLTSELTELKDHMDikdrkisVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQ 491
Cdd:PRK02224  407 LGNAEDFLEELREERD-------ELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEE 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  492 LRDQRDRAEHEKQEERDLHEREVAdykikLRAAESEVEKLQTRLERAV----TERERLEIKLEASQsELGKSKAELEkAT 567
Cdd:PRK02224  480 LEAELEDLEEEVEEVEERLERAED-----LVEAEDRIERLEERREDLEeliaERRETIEEKRERAE-ELRERAAELE-AE 552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  568 CEMGRSSAD-----WESTKQRIARLELENERLKHDLERsqttfgrttmttsqeLDRAQERADKAsAELRRTQAELRVTQS 642
Cdd:PRK02224  553 AEEKREAAAeaeeeAEEAREEVAELNSKLAELKERIES---------------LERIRTLLAAI-ADAEDEIERLREKRE 616

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767616  643 DAERA-REEAAALQEKLE-KSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMER 716
Cdd:PRK02224  617 ALAELnDERRERLAEKRErKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEE 692
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 410-636 7.03e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 7.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  410 QERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQM 489
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  490 AQLRDQRdraeheKQEERDLHEREVADYKIKLRAAES--EVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKAT 567
Cdd:COG4942   100 EAQKEEL------AELLRALYRLGRQPPLALLLSPEDflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386767616  568 CEMGRSSADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAE 636
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 202-570 1.14e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 1.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   202 KERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLEEELRLRMRQPNLEmqqqmeaiyAENDHLQREISILRETIKDL 281
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE---------ERIAQLSKELTELEAEIEEL 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   282 ECRVETQKQTLIARDESIKKLlemlqakgmgkEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQr 361
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEEL-----------EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA- 834

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   362 hiavlkeslcAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTqgtlqtvQERNRLTSELTELKDHMDIKDRKISVLQRKIE 441
Cdd:TIGR02168  835 ----------ATERRLEDLEEQIEELSEDIESLAAEIEELE-------ELIEELESELEALLNERASLEEALALLRSELE 897

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   442 NLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEeaigdkekqmAQLRDQRDRAEHEKQEERDLHEREVADYKIKL 521
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLE----------VRIDNLQERLSEEYSLTLEEAEALENKIEDDE 967

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 386767616   522 RAAESEVEKLQTRLER-------AVTERERLE---IKLEASQSELGKSKAELEKATCEM 570
Cdd:TIGR02168  968 EEARRRLKRLENKIKElgpvnlaAIEEYEELKeryDFLTAQKEDLTEAKETLEEAIEEI 1026
mukB PRK04863
chromosome partition protein MukB;
881-1271 1.45e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.87  E-value: 1.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  881 EAERSGLaaSKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEH----SRDRFDKLQTDiRRAQGEKEHFQ 956
Cdd:PRK04863  278 ANERRVH--LEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQdyqaASDHLNLVQTA-LRQQEKIERYQ 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  957 SELERVTYELERAHAAqtkasasVEAAKEEAAhyavELEKMRDRYEKSQVELRKlQDTDTFGR----ETRRLKEENERlr 1032
Cdd:PRK04863  355 ADLEELEERLEEQNEV-------VEEADEQQE----ENEARAEAAEEEVDELKS-QLADYQQAldvqQTRAIQYQQAV-- 420

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1033 ekldKTLMELETIRGKSQYESESFEKYKDKYekiemevQNMESKLHETSLQLElSKGEVAKMLANQEKQRSELERA---H 1109
Cdd:PRK04863  421 ----QALERAKQLCGLPDLTADNAEDWLEEF-------QAKEQEATEELLSLE-QKLSVAQAAHSQFEQAYQLVRKiagE 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1110 IEREKARDKHEKLLKEVDRLRLQQSSVSPgdpvRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELE 1189
Cdd:PRK04863  489 VSRSEAWDVARELLRRLREQRHLAEQLQQ----LRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELE 564

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1190 KAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAE----REALRQANRSGGAGAAPHPQLEKHVQKLESDVKQLA 1265
Cdd:PRK04863  565 ARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAwlaaQDALARLREQSGEEFEDSQDVTEYMQQLLERERELT 644


                  ....*.
gi 386767616 1266 MEREQL 1271
Cdd:PRK04863  645 VERDEL 650
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 410-551 1.59e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 1.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  410 QERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGA---------LTSLEE 480
Cdd:COG1579    24 HRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNkeyealqkeIESLKR 103

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767616  481 AIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEA 551
Cdd:COG1579   104 RISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 708-1587 1.95e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.50  E-value: 1.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   708 EKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLtydydnLQSQLDKALGQAARM 787
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKL------NEERIDLLQELLRDE 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   788 QKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSR 867
Cdd:pfam02463  250 QEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   868 CDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRR 947
Cdd:pfam02463  330 LKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   948 AQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDtdtfgrETRRLKEE 1027
Cdd:pfam02463  410 LLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLK------ETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1028 NERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELER 1107
Cdd:pfam02463  484 EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1108 AHIEREKARDKHEK----LLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGR 1183
Cdd:pfam02463  564 QKLVRALTELPLGArklrLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1184 LAKELEKAQMHLAKQQENTESTRIEFErMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLESDVKQ 1263
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSE-LTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1264 LAMEREqlvLQLEKSQEILMNFQKELQNAEAELQKTREENRKLRNghqvppvaappAGPSPAEFQAMQKEIQTLQQKLQE 1343
Cdd:pfam02463  723 LADRVQ---EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEE-----------EKSELSLKEKELAEEREKTEKLKV 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1344 SERALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMdqhIKDQHAQMQKMQQQMQQQQQ 1423
Cdd:pfam02463  789 EEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE---QKLEKLAEEELERLEEEITK 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1424 AAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRFQQQLEllvtelEKSKMSNQEQAKQLQTAQQQVQQLQ 1503
Cdd:pfam02463  866 EELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEE------KENEIEERIKEEAEILLKYEEEPEE 939

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1504 QQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKM 1583
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019


                   ....
gi 386767616  1584 AEFD 1587
Cdd:pfam02463 1020 KEFL 1023
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1157-1346 2.04e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 2.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1157 RQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQA 1236
Cdd:COG4942    26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1237 -----------NRSGGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRK 1305
Cdd:COG4942   106 laellralyrlGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 386767616 1306 LRNGHQVPPVAAPPAGPS-PAEFQAMQKEIQTLQQKLQESER 1346
Cdd:COG4942   186 ERAALEALKAERQKLLARlEKELAELAAELAELQQEAEELEA 227
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 157-564 2.57e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 2.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   157 LGDLQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSP--ELKKERAlrkeesakysliNDQLKLLSTENQKQAML 234
Cdd:TIGR04523  255 LNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEisDLNNQKE------------QDWNKELKSELKNQEKK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   235 VRQLEEELRLRMRQPNlEMQQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKL---LEMLQAKGM 311
Cdd:TIGR04523  323 LEEIQNQISQNNKIIS-QLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLesqINDLESKIQ 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   312 GKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQhqrhIAVLKESLCAKEEHYNMLQTDVEEMRARL 391
Cdd:TIGR04523  402 NQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQ----DSVKELIIKNLDNTRESLETQLKVLSRSI 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   392 EEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSS 471
Cdd:TIGR04523  478 NKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   472 EgaltsLEEAIGDKEKQMAQLR---DQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIK 548
Cdd:TIGR04523  558 N-----LEKEIDEKNKEIEELKqtqKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSI 632

                          410
                   ....*....|....*.
gi 386767616   549 LEASQSELGKSKAELE 564
Cdd:TIGR04523  633 IKNIKSKKNKLKQEVK 648
PLN02939 PLN02939
transferase, transferring glycosyl groups
 244-530 3.36e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.66  E-value: 3.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  244 LRMRQPNLEMQQQMEAIYAENDHLQREISILRETIKdlecrvETQKQTLIARDESIKklLEMLQAkgmgkeeerqmfqqm 323
Cdd:PLN02939  145 LLLNQARLQALEDLEKILTEKEALQGKINILEMRLS------ETDARIKLAAQEKIH--VEILEE--------------- 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  324 qamaqkQLDEFRLEIQRRdqeilamAAKMKTLEEQHQRHIAVLKESlcakeehyNM-LQTDVEEMRARLEEknrlIEKKT 402
Cdd:PLN02939  202 ------QLEKLRNELLIR-------GATEGLCVHSLSKELDVLKEE--------NMlLKDDIQFLKAELIE----VAETE 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  403 QGTLQTVQERNRLTSELTELK--------DHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGA 474
Cdd:PLN02939  257 ERVFKLEKERSLLDASLRELEskfivaqeDVSKLSPLQYDCWWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKL 336

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 386767616  475 LTSLEEAIGDK---------EKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEK 530
Cdd:PLN02939  337 EASLKEANVSKfssykvellQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKK 401
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1448-1698 4.05e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 4.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1448 KELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAgagat 1527
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE----- 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1528 dvQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEfdvQLRKRKEQMDQLEKSLQTQ 1607
Cdd:COG1196   314 --LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE---AEAELAEAEEELEELAEEL 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1608 GGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAATETERLLQLVQMSQEEQNAKEKTIMDLQQALKIAQAKVKQA 1687
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                         250
                  ....*....|.
gi 386767616 1688 QTQQQQQQDAG 1698
Cdd:COG1196   469 LEEAALLEAAL 479
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 338-1079 4.25e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.01  E-value: 4.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   338 IQRRDQEILAMAAKMKTLE---EQHQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEE-KNRLIEKKTQgtlqtvqeRN 413
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKnelKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDlNDKLKKNKDK--------IN 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   414 RLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSamqahhsSSEGALTSLEEAIGDKEKQMAQLR 493
Cdd:TIGR04523  100 KLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIK-------KKEKELEKLNNKYNDLKKQKEELE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   494 DQRDRAEHEKQEErdlhEREVADYKIKLRAAESEVEKLQTRLERavteRERLEIKLEASQSELGKSKAELEKATCEMGRS 573
Cdd:TIGR04523  173 NELNLLEKEKLNI----QKNIDKIKNKLLKLELLLSNLKKKIQK----NKSLESQISELKKQNNQLKDNIEKKQQEINEK 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   574 SADWESTKQRIARLELENERLKHDLERSQttfgrttmttsQELDRAQERADKASAELRRTQAELRVTqsdaerareeaaa 653
Cdd:TIGR04523  245 TTEISNTQTQLNQLKDEQNKIKKQLSEKQ-----------KELEQNNKKIKELEKQLNQLKSEISDL------------- 300

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   654 lqeKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSrihadrdrafseveKIKEEMERTQATLGKSQLQHEKLQN 733
Cdd:TIGR04523  301 ---NNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIIS--------------QLNEQISQLKKELTNSESENSEKQR 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   734 SLDKAQNEVDHLQDkldkactENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERD 813
Cdd:TIGR04523  364 ELEEKQNEIEKLKK-------ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETII 436

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   814 DAVTEVEILKEKLdkalYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIyrlqsrcdtaeadraRLEVEAERSGLAASKar 893
Cdd:TIGR04523  437 KNNSEIKDLTNQD----SVKELIIKNLDNTRESLETQLKVLSRSINKI---------------KQNLEQKQKELKSKE-- 495

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   894 EDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGE--KEHFQSELERVTYELERAHA 971
Cdd:TIGR04523  496 KELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFElkKENLEKEIDEKNKEIEELKQ 575

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   972 AQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQdtdtfgRETRRLKEENERLREKLDKTLMELETIRGKSQY 1051
Cdd:TIGR04523  576 TQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLE------KELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649

                          730       740
                   ....*....|....*....|....*...
gi 386767616  1052 ESESFEKYKDKYEKIEMEVQNMESKLHE 1079
Cdd:TIGR04523  650 IKETIKEIRNKWPEIIKKIKESKTKIDD 677
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
621-1238 4.43e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 4.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  621 ERADKASAELRRtqaELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVsrihadr 700
Cdd:PRK03918  161 ENAYKNLGEVIK---EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV------- 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  701 drafSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLdKACTENRRLVLEKEKLTYDYDNLQSQLDKA 780
Cdd:PRK03918  231 ----KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEI-EELEEKVKELKELKEKAEEYIKLSEFYEEY 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  781 LGQAARMQKERETLSLDTDRIREKLEktqmERDDAVTEVEILKEKLDKAlyasQKLIDEKDTSNKEFEKMLEKYDRAQNE 860
Cdd:PRK03918  306 LDELREIEKRLSRLEEEINGIEERIK----ELEEKEERLEELKKKLKEL----EKRLEELEERHELYEEAKAKKEELERL 377

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  861 IYRLQSRC------DTAEADRARLEVEAERSGLAASKAR-----EDLRKLQDESTRLQEACDRAALQLSRAKECEDNARS 929
Cdd:PRK03918  378 KKRLTGLTpeklekELEELEKAKEEIEEEISKITARIGElkkeiKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEY 457

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  930 ELEHSRDRFDKLQTDIRRAQGEKEhfQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELR 1009
Cdd:PRK03918  458 TAELKRIEKELKEIEEKERKLRKE--LRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLI 535

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1010 KLQ-DTDTFGRETRRLKEENERLREkLDKTLMELEtiRGKSQYESESFEKYKDKYEKIEMEVQNMEsKLHETSLQLELSK 1088
Cdd:PRK03918  536 KLKgEIKSLKKELEKLEELKKKLAE-LEKKLDELE--EELAELLKELEELGFESVEELEERLKELE-PFYNEYLELKDAE 611

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1089 GEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRlQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLE 1168
Cdd:PRK03918  612 KELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELE-KKYSEEEYEELREEYLELSRELAGLRAELEELEKRRE 690

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386767616 1169 KAlqSRDATELEAGRlaKELEKAQMHLAKqqentestrieFERMGAELGRLHDRLE--KAEAEREALRQANR 1238
Cdd:PRK03918  691 EI--KKTLEKLKEEL--EEREKAKKELEK-----------LEKALERVEELREKVKkyKALLKERALSKVGE 747
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
803-1308 4.66e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 4.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  803 EKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEA 882
Cdd:PRK03918  158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELK 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  883 ERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNAR--SELEHSRDRFDKLqtdirraqgekEHFQSELE 960
Cdd:PRK03918  238 EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKelKELKEKAEEYIKL-----------SEFYEEYL 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  961 RVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLdkTLM 1040
Cdd:PRK03918  307 DELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRL--TGL 384

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1041 ELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQL---------------ELSKGEVAKMLANQEKQRSEL 1105
Cdd:PRK03918  385 TPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrELTEEHRKELLEEYTAELKRI 464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1106 ERAHIEREKARDKHEKLLKEVDRLRLQQSSVSPgdpvrastssssalsagERQEIDRLRDrLEKALQSRDATELEA-GRL 1184
Cdd:PRK03918  465 EKELKEIEEKERKLRKELRELEKVLKKESELIK-----------------LKELAEQLKE-LEEKLKKYNLEELEKkAEE 526

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1185 AKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAphPQLEKHVQKLESDVKQL 1264
Cdd:PRK03918  527 YEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV--EELEERLKELEPFYNEY 604

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 386767616 1265 aMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRKLRN 1308
Cdd:PRK03918  605 -LELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRK 647
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 614-807 5.35e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 5.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  614 QELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGV 693
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  694 SRIHA------------------DRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTE 755
Cdd:COG4942   107 AELLRalyrlgrqpplalllspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEE 186

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 386767616  756 NRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEK 807
Cdd:COG4942   187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
341-468 5.79e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.46  E-value: 5.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  341 RDQEILAMAAKMKTLEEQHQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEkktqgtlqtvqernRLTSELT 420
Cdd:COG2433   386 IEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIE--------------RLERELS 451

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 386767616  421 ELKDHMDI---KDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHH 468
Cdd:COG2433   452 EARSEERReirKDREISRLDREIERLERELEEERERIEELKRKLERLKELW 502
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 170-848 6.98e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.65  E-value: 6.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   170 ELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLEEELrlrmrqp 249
Cdd:TIGR00606  249 PLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKEREL------- 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   250 nLEMQQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMgkeeERQMFQQMQAMAQK 329
Cdd:TIGR00606  322 -VDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGF----ERGPFSERQIKNFH 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   330 QLDEFRLEIQRR--DQEILAMAAKMKTLEEQHQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLiEKKTQGTLQ 407
Cdd:TIGR00606  397 TLVIERQEDEAKtaAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQL-EGSSDRILE 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   408 TVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLeDLLKEKdnqvdMARARLSAMQAHHSSSEGALTSLEEAIGDKEK 487
Cdd:TIGR00606  476 LDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKA-DLDRKL-----RKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDE 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   488 QMAQLRDQR-----------------DRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKL- 549
Cdd:TIGR00606  550 QIRKIKSRHsdeltsllgyfpnkkqlEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLf 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   550 -----EASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENE----------RLKHDLERSQTTFGRTTMTTSQ 614
Cdd:TIGR00606  630 dvcgsQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQsccpvcqrvfQTEAELQEFISDLQSKLRLAPD 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   615 ELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVS 694
Cdd:TIGR00606  710 KLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLT 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   695 RIHAdRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQnsLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQ 774
Cdd:TIGR00606  790 DVTI-MERFQMELKDVERKIAQQAAKLQGSDLDRTVQQ--VNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKT 866

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 386767616   775 SQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFE 848
Cdd:TIGR00606  867 NELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQ 940
PHA00430 PHA00430
tail fiber protein
 888-1017 7.05e-04

tail fiber protein


Pssm-ID: 222790 [Multi-domain]  Cd Length: 568  Bit Score: 44.11  E-value: 7.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  888 AASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELE 967
Cdd:PHA00430  167 EANRSRNEADRARNQAERFNNESGASATNTKQWRSEADGSNSEANRFKGYADSMTSSVEAAKGQAESSSKEANTAGDYAT 246

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 386767616  968 RAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTF 1017
Cdd:PHA00430  247 KAAASASAAHASEVNAANSATAAATSANRAKQQADRAKTEADKLGNMNGF 296
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 511-741 7.52e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 7.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  511 EREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKAtcemgrssadwestKQRIARLELE 590
Cdd:COG3883    22 QKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEA--------------EAEIEERREE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  591 -NERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLK 669
Cdd:COG3883    88 lGERARALYRSGGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELE 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386767616  670 AKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNE 741
Cdd:COG3883   168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 239
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
380-555 7.58e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 7.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  380 LQTDVEEMRARLEEKNRLIEKkTQGTLQTVQERNRLTSELTELKDHmdikDRKISVLQRKIENLEDLLKE---KDNQVDM 456
Cdd:COG4913   615 LEAELAELEEELAEAEERLEA-LEAELDALQERREALQRLAEYSWD----EIDVASAEREIAELEAELERldaSSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  457 ARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADY------KIKLRAAESEV-E 529
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleerfaAALGDAVERELrE 769

                         170       180
                  ....*....|....*....|....*.
gi 386767616  530 KLQTRLERAVTERERLEIKLEASQSE 555
Cdd:COG4913   770 NLEERIDALRARLNRAEEELERAMRA 795
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 485-748 1.00e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 43.26  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   485 KEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKikLRAAESEVEKLQTRLERAVTERerleIKLEASQSELGKSKAELE 564
Cdd:pfam15905   62 KKKSQKNLKESKDQKELEKEIRALVQERGEQDKR--LQALEEELEKVEAKLNAAVREK----TSLSASVASLEKQLLELT 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   565 KATcEMGRSSADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDA 644
Cdd:pfam15905  136 RVN-ELLKAKFSEDGTQKKMSSLSMELMKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEK 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   645 ERAREEAAAL----------QEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEM 714
Cdd:pfam15905  215 IEEKSETEKLleyitelscvSEQVEKYKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQIKDLNEKCKLLESEKEEL 294

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 386767616   715 ERTQATLGKSQLQH-EKLQNSLDKAQNEVDHLQDK 748
Cdd:pfam15905  295 LREYEEKEQTLNAElEELKEKLTLEEQEHQKLQQK 329
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
436-817 1.09e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.88  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  436 LQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHER--- 512
Cdd:PRK02224  347 LREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDElre 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  513 EVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLElENE 592
Cdd:PRK02224  427 REAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLV 505

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  593 RLKHDLERSQTTFGRTTMTTSQELDRAQERADKAsAELRRTQAELRvtqSDAERAREEAAALQEKLEKSQGEVyrlkAKL 672
Cdd:PRK02224  506 EAEDRIERLEERREDLEELIAERRETIEEKRERA-EELRERAAELE---AEAEEKREAAAEAEEEAEEAREEV----AEL 577

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  673 ENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERT---QATLGKSQLQHEKLQNSLDKAQneVDHLQDKL 749
Cdd:PRK02224  578 NSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNderRERLAEKRERKRELEAEFDEAR--IEEAREDK 655

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 386767616  750 DKACTENRRLVLEKEKLTYDYDNLQsqldKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVT 817
Cdd:PRK02224  656 ERAEEYLEQVEEKLDELREERDDLQ----AEIGAVENELEELEELRERREALENRVEALEALYDEAEE 719
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
331-528 1.22e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  331 LDEFRLEIQRRDQEILAMAAKMKTLEEQHQRHIAVLKeslcakeehYNMLQTDVEEMRARLEEKNRLIEK--KTQGTLQT 408
Cdd:COG4913   619 LAELEEELAEAEERLEALEAELDALQERREALQRLAE---------YSWDEIDVASAEREIAELEAELERldASSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  409 VQER-NRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDmaraRLSAMQAHHSSSEGALTSLEEAIGDKEK 487
Cdd:COG4913   690 LEEQlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----AAEDLARLELRALLEERFAAALGDAVER 765

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 386767616  488 QM-AQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEV 528
Cdd:COG4913   766 ELrENLEERIDALRARLNRAEEELERAMRAFNREWPAETADL 807
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
331-541 1.73e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  331 LDEFRLEIQRRDQEILAMAAKMKTLEEQHQRHIAVLkeSLCAKEEHYNMLQTDVEEMRARLEEKNRLIEK--KTQGTLQT 408
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDALQERR--EALQRLAEYSWDEIDVASAEREIAELEAELERldASSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  409 VQER-NRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDmararlsamQAHHSSSEGALTSLEEaigdkek 487
Cdd:COG4913   690 LEEQlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE---------AAEDLARLELRALLEE------- 753

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 386767616  488 qmaqLRDQRDRAEHEKQEERDLHERevadykikLRAAESEVEKLQTRLERAVTE 541
Cdd:COG4913   754 ----RFAAALGDAVERELRENLEER--------IDALRARLNRAEEELERAMRA 795
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1448-1683 1.85e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1448 KELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGAT 1527
Cdd:COG1196   260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1528 DVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEfdvQLRKRKEQMDQLEKSLQTQ 1607
Cdd:COG1196   340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---LAAQLEELEEAEEALLERL 416

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767616 1608 GGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAATETERLLQLVQMSQEEQNAKEKTIMDLQQALKIAQAK 1683
Cdd:COG1196   417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 626-890 1.97e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 1.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  626 ASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQsgvsrihADRDRAFS 705
Cdd:COG3883    14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAE-------AEIEERRE 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  706 EVEKIKEEMERTQATLGKSQ--LQHEKLQNSLDKAQNevdhlqdkLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQ 783
Cdd:COG3883    87 ELGERARALYRSGGSVSYLDvlLGSESFSDFLDRLSA--------LSKIADADADLLEELKADKAELEAKKAELEAKLAE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  784 AARMQKERETLSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYR 863
Cdd:COG3883   159 LEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238

                         250       260
                  ....*....|....*....|....*..
gi 386767616  864 LQSRCDTAEADRARLEVEAERSGLAAS 890
Cdd:COG3883   239 AAAAAASAAGAGAAGAAGAAAGSAGAA 265
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 336-500 1.97e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 1.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  336 LEIQRRDQEILAMAAKMKTLEEQ---HQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKT--QGTLQTVQ 410
Cdd:COG1579    10 LDLQELDSELDRLEHRLKELPAElaeLEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEeqLGNVRNNK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  411 ERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAhhsssegaltSLEEAIGDKEKQMA 490
Cdd:COG1579    90 EYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKA----------ELDEELAELEAELE 159

                         170
                  ....*....|
gi 386767616  491 QLRDQRDRAE 500
Cdd:COG1579   160 ELEAEREELA 169
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 615-792 2.34e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 2.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  615 ELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKA----- 689
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaraly 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  690 ------------------------QSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEvdhL 745
Cdd:COG3883    97 rsggsvsyldvllgsesfsdfldrLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE---L 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 386767616  746 QDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERE 792
Cdd:COG3883   174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1160-1371 2.42e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 2.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1160 IDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRS 1239
Cdd:COG4372    26 IAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELES 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1240 GGAGAAphpQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRKLRNGHQVPPVAAPP 1319
Cdd:COG4372   106 LQEEAE---ELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAE 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 386767616 1320 AGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASREEIEQ 1371
Cdd:COG4372   183 QALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLA 234
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 380-586 2.53e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 2.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  380 LQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEkdnqvdmaRA 459
Cdd:COG3883    21 KQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE--------RA 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  460 RLSAMQAHHSSSEGAL---TSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDL--HEREVADYKIKLRAAESEVEKLQTR 534
Cdd:COG3883    93 RALYRSGGSVSYLDVLlgsESFSDFLDRLSALSKIADADADLLEELKADKAELeaKKAELEAKLAELEALKAELEAAKAE 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 386767616  535 LERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIAR 586
Cdd:COG3883   173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
Tropomyosin pfam00261
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ...
 487-721 2.91e-03

Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.


Pssm-ID: 459736 [Multi-domain]  Cd Length: 235  Bit Score: 41.17  E-value: 2.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   487 KQMAQLRDQRDRAEHEKQEERDLHEREVAdykiKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELgkskAELEKA 566
Cdd:pfam00261    1 KKMQQIKEELDEAEERLKEAMKKLEEAEK----RAEKAEAEVAALNRRIQLLEEELERTEERLAEALEKL----EEAEKA 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   567 TCEMGRSSADWESTKQ----RIARLEL---ENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRV 639
Cdd:pfam00261   73 ADESERGRKVLENRALkdeeKMEILEAqlkEAKEIAEEADRKYEEVARKLVVVEGDLERAEERAELAESKIVELEEELKV 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   640 TQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQA 719
Cdd:pfam00261  153 VGNNLKSLEASEEKASEREDKYEEQIRFLTEKLKEAETRAEFAERSVQKLEKEVDRLEDELEAEKEKYKAISEELDQTLA 232


                   ..
gi 386767616   720 TL 721
Cdd:pfam00261  233 EL 234
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
887-1138 3.62e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 3.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  887 LAASKAREDLRKLQDESTRLqeacDRAALQLSRAKECEDnARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYEL 966
Cdd:COG4913   218 LEEPDTFEAADALVEHFDDL----ERAHEALEDAREQIE-LLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  967 ERAHAAQTKASASVEAAKEEAAhyAVELEKMRDRYEKSQVELRKLQdtdtfGRETRRLKEENERLREKLDKTLMELetir 1046
Cdd:COG4913   293 LEAELEELRAELARLEAELERL--EARLDALREELDELEAQIRGNG-----GDRLEQLEREIERLERELEERERRR---- 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1047 gksqyesesfEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAhieREKARDKHEKLLKEV 1126
Cdd:COG4913   362 ----------ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA---LRDLRRELRELEAEI 428

                         250
                  ....*....|..
gi 386767616 1127 DRLRLQQSSVSP 1138
Cdd:COG4913   429 ASLERRKSNIPA 440
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 429-642 3.86e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 3.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  429 KDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQ-RDRAEHEKQEER 507
Cdd:COG3883    21 KQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREElGERARALYRSGG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  508 DLHEREV-------ADYKIKLRAaeseVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMgrssadwEST 580
Cdd:COG3883   101 SVSYLDVllgsesfSDFLDRLSA----LSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAEL-------EAA 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386767616  581 KQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQS 642
Cdd:COG3883   170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 579-742 4.35e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 41.53  E-value: 4.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   579 STKQRIARLELENER---LKHDL----ERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEA 651
Cdd:pfam05262  178 SDKKVVEALREDNEKgvnFRRDMtdlkERESQEDAKRAQQLKEELDKKQIDADKAQQKADFAQDNADKQRDEVRQKQQEA 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   652 AALQEKLEKSQGEVYRLKAklENAQGEQESLRQELEKAQSGVSRihADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKL 731
Cdd:pfam05262  258 KNLPKPADTSSPKEDKQVA--ENQKREIEKAQIEIKKNDEEALK--AKDHKAFDLKQESKASEKEAEDKELEAQKKREPV 333

                          170
                   ....*....|.
gi 386767616   732 QNSLDKAQNEV 742
Cdd:pfam05262  334 AEDLQKTKPQV 344
PRK12704 PRK12704
phosphodiesterase; Provisional
 968-1126 5.38e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 5.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  968 RAHAAQTKASASVEAAKEEAAHYAVELE-KMRDRYE--KSQVELRKLQDTDTFGRETRRLKEENERLREK---LDKTLME 1041
Cdd:PRK12704   32 KIKEAEEEAKRILEEAKKEAEAIKKEALlEAKEEIHklRNEFEKELRERRNELQKLEKRLLQKEENLDRKlelLEKREEE 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616 1042 LETIRGKSQYESESFEKYKDKYEKIEMEVQNmesKLHETSlqlELSKGEVAKMLANQEKQRSELERAHIER---EKARDK 1118
Cdd:PRK12704  112 LEKKEKELEQKQQELEKKEEELEELIEEQLQ---ELERIS---GLTAEEAKEILLEKVEEEARHEAAVLIKeieEEAKEE 185


                  ....*...
gi 386767616 1119 HEKLLKEV 1126
Cdd:PRK12704  186 ADKKAKEI 193
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 626-893 5.78e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 5.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  626 ASAELRRTQAELRvtqsdaerareeaaALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQsgvsrihadrdrafS 705
Cdd:COG4942    18 QADAAAEAEAELE--------------QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA--------------R 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  706 EVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVL----EKEKLTYDYDNLQSQLDKAL 781
Cdd:COG4942    70 RIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARR 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  782 GQAARMQKERETLsldtDRIREKLEKTQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNei 861
Cdd:COG4942   150 EQAEELRADLAEL----AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE-- 223

                         250       260       270
                  ....*....|....*....|....*....|..
gi 386767616  862 yRLQSRCDTAEADRARLEVEAERSGLAASKAR 893
Cdd:COG4942   224 -ELEALIARLEAEAAAAAERTPAAGFAALKGK 254
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
464-920 6.04e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 6.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  464 MQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERE 543
Cdd:COG4717    40 LAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  544 RLEIKLEASQSELGKSKAELEKATC-----EMGRSSADWESTKQRIARLELENERLKHDLERsqtTFGRTTMTTSQELDR 618
Cdd:COG4717   120 KLEKLLQLLPLYQELEALEAELAELperleELEERLEELRELEEELEELEAELAELQEELEE---LLEQLSLATEEELQD 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  619 AQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLE-NAQGEQESLRQELEKAQSGVSRIH 697
Cdd:COG4717   197 LAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLlLIAAALLALLGLGGSLLSLILTIA 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  698 ADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQL 777
Cdd:COG4717   277 GVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA 356

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  778 DKALGQAARMQKERETLSL-------DTDRIREKLEKTQmERDDAVTEVEILKEKLDKALYASQKLIDEKDtsnkeFEKM 850
Cdd:COG4717   357 EELEEELQLEELEQEIAALlaeagveDEEELRAALEQAE-EYQELKEELEELEEQLEELLGELEELLEALD-----EEEL 430

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386767616  851 LEKYDRAQNEIYRLQSRCDTAEADRARLEVEAER--SGLAASKAREDLRKLQDESTRLQEacDRAALQLSRA 920
Cdd:COG4717   431 EEELEELEEELEELEEELEELREELAELEAELEQleEDGELAELLQELEELKAELRELAE--EWAALKLALE 500
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 668-752 6.04e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 40.87  E-value: 6.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   668 LKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGK-SQLQHEKLQNSLDKAQNEVDHLQ 746
Cdd:TIGR04320  259 LQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQtAQNNLATAQAALANAEARLAKAK 338


                   ....*.
gi 386767616   747 DKLDKA 752
Cdd:TIGR04320  339 EALANL 344
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
588-1006 6.20e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 6.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  588 ELENERLKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRvTQSDAERAREEAAALQEKLEKSQGEVYR 667
Cdd:COG4717    72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE-KLLQLLPLYQELEALEAELAELPERLEE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  668 LKAKLEnaqgEQESLRQELEKAQSGVSRIHADRDRAFSEV-EKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQ 746
Cdd:COG4717   151 LEERLE----ELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  747 DKLDKACTENRRLVLEKEK---------------LTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQME 811
Cdd:COG4717   227 EELEQLENELEAAALEERLkearlllliaaallaLLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  812 RDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEI------YRLQSRCDTAEADRARLEVEAERS 885
Cdd:COG4717   307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAeeleeeLQLEELEQEIAALLAEAGVEDEEE 386

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  886 GLAASKAREDLRKLQDESTRLQEACDRAA--LQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVT 963
Cdd:COG4717   387 LRAALEQAEEYQELKEELEELEEQLEELLgeLEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLE 466

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 386767616  964 YELERAHAAQTKASASVEAAKEEAAHYAVE-----LEKMRDRYEKSQV 1006
Cdd:COG4717   467 EDGELAELLQELEELKAELRELAEEWAALKlalelLEEAREEYREERL 514
46 PHA02562
endonuclease subunit; Provisional
 343-565 6.57e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.15  E-value: 6.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  343 QEILAMAAKMKTLEEQ---HQRHIAVLKESLCAK-EEHYNMLQTDVEEMRARLEEKNRLIEKktqgTLQTVQERNRLTSE 418
Cdd:PHA02562  181 QQIQTLDMKIDHIQQQiktYNKNIEEQRKKNGENiARKQNKYDELVEEAKTIKAEIEELTDE----LLNLVMDIEDPSAA 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  419 LTELKDHMDIKDRKISVLQRKIENLED---------LLKEKDNQVDMARARLSAMQahhssseGALTSLEEAIGDKEKQM 489
Cdd:PHA02562  257 LNKLNTAAAKIKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQ-------HSLEKLDTAIDELEEIM 329

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767616  490 AQLRDQRDRAeHEKQEERDLHEREVADYKIKLRAAESEVEKLQtrlERAVTERERLEiKLEASQSELGKSKAELEK 565
Cdd:PHA02562  330 DEFNEQSKKL-LELKNKISTNKQSLITLVDKAKKVKAAIEELQ---AEFVDNAEELA-KLQDELDKIVKTKSELVK 400
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 886-1116 6.93e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 6.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  886 GLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAqgekehfQSELERVTYE 965
Cdd:COG4942    12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAL-------EQELAALEAE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  966 LERAHAAQTKASASVEAAKEEAAHYAVELEKM-RDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTLMELET 1044
Cdd:COG4942    85 LAELEKEIAELRAELEAQKEELAELLRALYRLgRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 386767616 1045 IRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELER--AHIEREKAR 1116
Cdd:COG4942   165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAliARLEAEAAA 238
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 595-1346 7.48e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.26  E-value: 7.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   595 KHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEvyrLKAKLEN 674
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQED---LRNQLQN 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   675 AQgeqeslrQELEKAQSgvsrihadrdrafsevekIKEEMERTQATLGKsqlQHEKLQNSLDKAQNEVDHLQDKLDKAct 754
Cdd:pfam15921  150 TV-------HELEAAKC------------------LKEDMLEDSNTQIE---QLRKMMLSHEGVLQEIRSILVDFEEA-- 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   755 enrrlvleKEKLTYDYDNLQSQLDKALGQA-ARMQKERET-LSLDTDRIREKLEKTQMERDDAVTEVEILKEKLDKALya 832
Cdd:pfam15921  200 --------SGKKIYEHDSMSTMHFRSLGSAiSKILRELDTeISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRI-- 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   833 sQKLIDEKDTsnkEFEKMLEKYDRA---------QNEIYRLQSRCDTAEADRARLEVEAERSGLaASKAREDLRKLQDES 903
Cdd:pfam15921  270 -EQLISEHEV---EITGLTEKASSArsqansiqsQLEIIQEQARNQNSMYMRQLSDLESTVSQL-RSELREAKRMYEDKI 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   904 TRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAqgekehfQSELERVTYELERAHAAQTKASASVEAA 983
Cdd:pfam15921  345 EELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKR-------EKELSLEKEQNKRLWDRDTGNSITIDHL 417

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616   984 KEEAAHYAVELEKMRDRYEKSQVELRKLQDtdtfgRETRRLKEENERLrEKLDKTLMELETIRGKSQYESESFEKYKDKY 1063
Cdd:pfam15921  418 RRELDDRNMEVQRLEALLKAMKSECQGQME-----RQMAAIQGKNESL-EKVSSLTAQLESTKEMLRKVVEELTAKKMTL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1064 EKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHekllKEVDRLRLQQSsvspgdpvr 1143
Cdd:pfam15921  492 ESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQ----TECEALKLQMA--------- 558

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1144 astsSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLakqqentESTRIEFERMGAELGRLHDRL 1223
Cdd:pfam15921  559 ----EKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLEL-------QEFKILKDKKDAKIRELEARV 627

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  1224 EKAEAEREALRQAN----RSGGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLE-KSQEILMNFQK---ELQNAEAE 1295
Cdd:pfam15921  628 SDLELEKVKLVNAGserlRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRnKSEEMETTTNKlkmQLKSAQSE 707

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 386767616  1296 LQKTREENRKLR--NGH--QVPPVAAPPAGPSPAEFQAMQKEIQTLQQKLQESER 1346
Cdd:pfam15921  708 LEQTRNTLKSMEgsDGHamKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANK 762
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
390-818 7.67e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.91  E-value: 7.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  390 RLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDnqvdmARARLSAMQAHHS 469
Cdd:COG4717    75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEA-----LEAELAELPERLE 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  470 SSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKL 549
Cdd:COG4717   150 ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  550 EASQSELGKSKAE-----------LEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQTTFGRTTMTTSQELDR 618
Cdd:COG4717   230 EQLENELEAAALEerlkearllllIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQA 309

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  619 AQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQEsLRQELEKAQSGVSRIHA 698
Cdd:COG4717   310 LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQE-IAALLAEAGVEDEEELR 388

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  699 DRDRAFSEVEKIKEEMERTQATLGK---------SQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYD 769
Cdd:COG4717   389 AALEQAEEYQELKEELEELEEQLEEllgeleellEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEED 468

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 386767616  770 --YDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQMERDDAVTE 818
Cdd:COG4717   469 geLAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLE 519
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
415-537 8.58e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.00  E-value: 8.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  415 LTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEkdnqvdmararlsaMQAHHSSSEGALTSLEEAIGDKEKQMAQLRD 494
Cdd:COG2433   390 LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVER--------------LEAEVEELEAELEEKDERIERLERELSEARS 455

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 386767616  495 QRdRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLER 537
Cdd:COG2433   456 EE-RREIRKDREISRLDREIERLERELEEERERIEELKRKLER 497
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 502-695 9.31e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.20  E-value: 9.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  502 EKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADW---- 577
Cdd:COG3883    27 ELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVsyld 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  578 -----ESTKQRIARLELENerlkhDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDaerareeaa 652
Cdd:COG3883   107 vllgsESFSDFLDRLSALS-----KIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE--------- 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 386767616  653 aLQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSR 695
Cdd:COG3883   173 -LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
594-822 9.90e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.77  E-value: 9.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  594 LKHDLERSQTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDaerarEEAAALQEKLEKSQGEVYRLKAKLE 673
Cdd:COG3206   162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLS-----EEAKLLLQQLSELESQLAEARAELA 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  674 NAQGEQESLRQELEKAQSGVSRIHADR--DRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLdK 751
Cdd:COG3206   237 EAEARLAALRAQLGSGPDALPELLQSPviQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI-L 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767616  752 ACTENRRLVLEKEKltydyDNLQSQLDKALGQAARM-QKERETLSLDTDR---------IREKLEKTQMERDDAVTEVEI 821
Cdd:COG3206   316 ASLEAELEALQARE-----ASLQAQLAQLEARLAELpELEAELRRLEREVevarelyesLLQRLEEARLAEALTVGNVRV 390


                  .
gi 386767616  822 L 822
Cdd:COG3206   391 I 391
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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