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Conserved domains on  [gi|392900106|ref|NP_001255402|]
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GATA-type domain-containing protein [Caenorhabditis elegans]

Protein Classification

GATA-type transcription factor( domain architecture ID 10078896)

GATA-type transcription factor binds to the DNA consensus sequence [AT]GATA[AG] and may function as a transcription factor/regulator

CATH:  3.30.50.10
Gene Ontology:  GO:0003700|GO:0006357|GO:0008270|GO:0043565
PubMed:  31574210
SCOP:  4003617

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 342-393 6.55e-21

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 85.89  E-value: 6.55e-21
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 392900106 342 ECVNCRTNTTTLWRRNG-EGHPVCNACGLYFKLHKVERPITMKK-DGIQTRNRK 393
Cdd:cd00202    1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 288-333 3.13e-19

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 81.26  E-value: 3.13e-19
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 392900106 288 ECVNCGVHNTPLWRRDGS-GNYLCNACGLYFKMNHHARPLVKPKKRQ 333
Cdd:cd00202    1 ACSNCGTTTTPLWRRGPSgGSTLCNACGLYWKKHGVMRPLSKRKKDQ 47
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 342-393 6.55e-21

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 85.89  E-value: 6.55e-21
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 392900106 342 ECVNCRTNTTTLWRRNG-EGHPVCNACGLYFKLHKVERPITMKK-DGIQTRNRK 393
Cdd:cd00202    1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 288-333 3.13e-19

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 81.26  E-value: 3.13e-19
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 392900106 288 ECVNCGVHNTPLWRRDGS-GNYLCNACGLYFKMNHHARPLVKPKKRQ 333
Cdd:cd00202    1 ACSNCGTTTTPLWRRGPSgGSTLCNACGLYWKKHGVMRPLSKRKKDQ 47
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
285-332 3.44e-17

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 75.15  E-value: 3.44e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 392900106   285 EDRECVNCGVHNTPLWRRDGSGN-YLCNACGLYFKM-NHHARPLVKPKKR 332
Cdd:smart00401   2 SGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKhGGLKRPLSLKKDG 51
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
338-387 4.67e-17

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 74.76  E-value: 4.67e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 392900106   338 RTGIECVNCRTNTTTLWRRNGEGH-PVCNACGLYFKLH-KVERPITMKKDGI 387
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHgGLKRPLSLKKDGI 52
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 289-322 1.48e-13

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 64.65  E-value: 1.48e-13
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 392900106  289 CVNCGVHNTPLWRRDGSGNY-LCNACGLYFKMNHH 322
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 343-376 1.10e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 61.95  E-value: 1.10e-12
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 392900106  343 CVNCRTNTTTLWRRNGEGHP-VCNACGLYFKLHKV 376
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
343-398 1.09e-07

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 54.11  E-value: 1.09e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392900106 343 CVNCRTNTTTLWRRNGE-----GHPVCNACGLYFKLHKVER-PITMKKDGIQTRNRKLSAKG 398
Cdd:COG5641  161 CSNCKTTSTPLWRRASSesslpGNNLCNACGLYLKLHGSPRaPISLKSDSIKSRSSRSSHNN 222
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 342-393 6.55e-21

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 85.89  E-value: 6.55e-21
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 392900106 342 ECVNCRTNTTTLWRRNG-EGHPVCNACGLYFKLHKVERPITMKK-DGIQTRNRK 393
Cdd:cd00202    1 ACSNCGTTTTPLWRRGPsGGSTLCNACGLYWKKHGVMRPLSKRKkDQIKRRNRK 54
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 288-333 3.13e-19

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 81.26  E-value: 3.13e-19
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 392900106 288 ECVNCGVHNTPLWRRDGS-GNYLCNACGLYFKMNHHARPLVKPKKRQ 333
Cdd:cd00202    1 ACSNCGTTTTPLWRRGPSgGSTLCNACGLYWKKHGVMRPLSKRKKDQ 47
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
285-332 3.44e-17

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 75.15  E-value: 3.44e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 392900106   285 EDRECVNCGVHNTPLWRRDGSGN-YLCNACGLYFKM-NHHARPLVKPKKR 332
Cdd:smart00401   2 SGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKhGGLKRPLSLKKDG 51
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
338-387 4.67e-17

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 74.76  E-value: 4.67e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 392900106   338 RTGIECVNCRTNTTTLWRRNGEGH-PVCNACGLYFKLH-KVERPITMKKDGI 387
Cdd:smart00401   1 GSGRSCSNCGTTETPLWRRGPSGNkTLCNACGLYYKKHgGLKRPLSLKKDGI 52
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 289-322 1.48e-13

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 64.65  E-value: 1.48e-13
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 392900106  289 CVNCGVHNTPLWRRDGSGNY-LCNACGLYFKMNHH 322
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 343-376 1.10e-12

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 61.95  E-value: 1.10e-12
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 392900106  343 CVNCRTNTTTLWRRNGEGHP-VCNACGLYFKLHKV 376
Cdd:pfam00320   1 CSNCGTTKTPLWRRGPNGNRtLCNACGLYYKKKGL 35
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
343-398 1.09e-07

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 54.11  E-value: 1.09e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392900106 343 CVNCRTNTTTLWRRNGE-----GHPVCNACGLYFKLHKVER-PITMKKDGIQTRNRKLSAKG 398
Cdd:COG5641  161 CSNCKTTSTPLWRRASSesslpGNNLCNACGLYLKLHGSPRaPISLKSDSIKSRSSRSSHNN 222
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
263-372 4.07e-06

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 49.10  E-value: 4.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900106 263 PKNTISKANRSSGgANNSQFSTEDRECVNCGVHNTPLWRRDGS-----GNYLCNACGLYFKM-NHHARPLVKPKKRQNAQ 336
Cdd:COG5641  136 TLNPGGTSSLNPN-NNQSDNSNQPHVCSNCKTTSTPLWRRASSesslpGNNLCNACGLYLKLhGSPRAPISLKSDSIKSR 214

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 392900106 337 KRTGIECVNCRTNTTTLWRRNGEGHPVCNACGLYFK 372
Cdd:COG5641  215 SSRSSHNNNDSNGENANTESIGNSSASKLTKSWEER 250
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
263-398 5.31e-04

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 42.55  E-value: 5.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900106 263 PKNTISKANRSSG-GANNSQFST---EDRECVNCGVHN-TPLWRR-DGSGNYLCNACGLYFKMNHHARPLVkPKKRQNAQ 336
Cdd:COG5641  270 PKSPLLEGLMGSTsLQPVSTPKLvlpSDKKRSTLTTSTaTPLWRRtSDKSSFSCNASGSALKPPGSKRPLL-PKPDPNSK 348

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392900106 337 KRTGIeCVNCRTNTTTLWRrngEGHPVCNACGLYFKLHKVERPITMKKDGIqTRNRKLSAKG 398
Cdd:COG5641  349 RSNAT-CMNCSSTPTNKIL---SPPTTSNSPGAQVKLPNQTRSTGATKKKI-TRRRMNSGKI 405
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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