|
Name |
Accession |
Description |
Interval |
E-value |
| Dynactin |
pfam12455 |
Dynein associated protein; This domain family is found in eukaryotes, and is approximately 280 ... |
630-914 |
1.94e-57 |
|
Dynein associated protein; This domain family is found in eukaryotes, and is approximately 280 amino acids in length. The family is found in association with pfam01302. There is a single completely conserved residue E that may be functionally important. Dynactin has been associated with Dynein, a kinesin protein which is involved in organelle transport, mitotic spindle assembly and chromosome segregation. Dynactin anchors Dynein to specific subcellular structures.
Pssm-ID: 463591 Cd Length: 287 Bit Score: 200.53 E-value: 1.94e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 630 LNSQIQDQKDQVLSLEEQlhghisvDNDRASMVN-------QLQISANRNFAEDVERQVNAIEVEFARRQAGYLKAFLPD 702
Cdd:pfam12455 1 LQSDLEDLRASQQITESE-------SEDLSSRSRammdlnlKLQSSASKAQAKAIDLELRRLEAQQASEHLEIVQLFLPD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 703 NFSRVGgENDSILLVVMLPRLAAKTKLFASLAAQCFPQVPGgmrreHVTKSHKGEQWAHVARVNYLANSINAALGKLESA 782
Cdd:pfam12455 74 SFLRRG-DRDSVLALLLFKRLAFKADLLASQIREKFPLSES-----LILKGHVEEQLFFACELLEKLTWLSALCDRFAAA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 783 IGETTVEVLIKLTETYGEMSTHEKTVDQYLELLKKSRFDENTSLDSFVRPLVYFQNMFSLHIGGDGFNAAHWVSEICASL 862
Cdd:pfam12455 148 LRSCSVETFLKIGGAYPELEPVERALDGWIDLLKRDELDENECAEELQRSIAYFSHLAEVHLADSLEDLADELLMRVLLL 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 863 SAGLAYCRVNTQRISYFLQESIT--------AGEVYNMLQTLNDEFAACESVILKAYRLL 914
Cdd:pfam12455 228 QSALDSIAAALGRLKTLLQSGLPdpdggdeeASDLFELLQTLITQARSAKVISKKILRRL 287
|
|
| CAP_GLY |
pfam01302 |
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ... |
5-68 |
2.85e-24 |
|
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 460154 [Multi-domain] Cd Length: 65 Bit Score: 97.09 E-value: 2.85e-24
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 392900641 5 IGTRVKTSSG-NGRVVFCGQTQFAEGDWVGVILDTATGKNNGTVQNVQYFECEPNFGVFVKSSAV 68
Cdd:pfam01302 1 VGDRVEVPGGrRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
|
|
| CAP_GLY |
smart01052 |
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ... |
5-69 |
1.20e-21 |
|
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 214997 [Multi-domain] Cd Length: 68 Bit Score: 89.57 E-value: 1.20e-21
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 392900641 5 IGTRVKTSSGN--GRVVFCGQTQFAEGDWVGVILDTAT-GKNNGTVQNVQYFECEPNFGVFVKSSAVE 69
Cdd:smart01052 1 VGDRVEVGGGGrrGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
371-735 |
1.49e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.66 E-value: 1.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 371 ITELEKQIgdERIAKE--------QLQAWQDENKVLLSDHQDtmEMATIEKELAEERADSLQNDVLTLTEKLESMETELE 442
Cdd:COG1196 195 LGELERQL--EPLERQaekaeryrELKEELKELEAELLLLKL--RELEAELEELEAELEELEAELEELEAELAELEAELE 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 443 ILKEEMANgggaaqvgnsvQMKQIEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIA 522
Cdd:COG1196 271 ELRLELEE-----------LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 523 ESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHEL 602
Cdd:COG1196 340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 603 NGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLHGHISVDNDRASMVNQLQISANRnfAEDVERQVN 682
Cdd:COG1196 420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLL 497
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 392900641 683 AIEVEFARRQAGYLKAFLPDNFSRVGGENDSILLVVMLPRLAAKTKLFASLAA 735
Cdd:COG1196 498 EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQN 550
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
331-687 |
1.42e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.33 E-value: 1.42e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 331 EKLEAARVKRKEDHTKVmELDRVSFELRSSEEVRSRLIQKITELEKQIGDerIAKEQLQAWQDENKvllsdhqdtmemat 410
Cdd:TIGR02169 672 EPAELQRLRERLEGLKR-ELSSLQSELRRIENRLDELSQELSDASRKIGE--IEKEIEQLEQEEEK-------------- 734
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 411 iEKELAEERADSLQndvlTLTEKLESMETELEILKEEMAngggaaqvgnsvqmkQIEIQNDKLKDALIKLRDLNAQATLd 490
Cdd:TIGR02169 735 -LKERLEELEEDLS----SLEQEIENVKSELKELEARIE---------------ELEEDLHKLEEALNDLEARLSHSRI- 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 491 rQKAVDEAERLKTENSELIRVAENLKRQT-------EIAESKIAGFQEQIDAAmgaeamvtqltdknfnmEERIMQLEET 563
Cdd:TIGR02169 794 -PEIQAELSKLEEEVSRIEARLREIEQKLnrltlekEYLEKEIQELQEQRIDL-----------------KEQIKSIEKE 855
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 564 IEDME-EARDLDEQLAEVQKqQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVL 642
Cdd:TIGR02169 856 IENLNgKKEELEEELEELEA-ALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS 934
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 392900641 643 SLEEQLHGHISvdndrasmvnqlqISANRNFAEDVERQVNAIEVE 687
Cdd:TIGR02169 935 EIEDPKGEDEE-------------IPEEELSLEDVQAELQRVEEE 966
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
356-648 |
6.89e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.00 E-value: 6.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 356 ELRSSEEVRSRLIQKITELEKQIGDERIA-------KEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERADSLQNDVL 428
Cdd:TIGR02168 678 EIEELEEKIEELEEKIAELEKALAELRKEleeleeeLEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 429 TLTEKLESMETELEILKEEMANGGG-----AAQVGN-SVQMKQIEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLK 502
Cdd:TIGR02168 758 ELEAEIEELEERLEEAEEELAEAEAeieelEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE 837
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 503 TENSELIRVAENLKRQTEIAESKIAGFQEQIDAamgAEAMVTQLTDKNFNMEERIM-------QLEETIEDMEEARDLDE 575
Cdd:TIGR02168 838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEE---LESELEALLNERASLEEALAllrseleELSEELRELESKRSELR 914
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 392900641 576 QLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKhavDLSQTILkfrERMANLNSQIQDQKDQVLSLEEQL 648
Cdd:TIGR02168 915 RELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS---LTLEEAE---ALENKIEDDEEEARRRLKRLENKI 981
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
318-596 |
7.64e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 66.88 E-value: 7.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRVSFELR-SSEEVRSRLIQKITELEKQIGDERIAKEQLQawqdenk 396
Cdd:COG1196 240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELElELEEAQAEEYELLAELARLEQDIARLEERRR------- 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 397 vllsDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMAngggaaqvgnsvqmkQIEIQNDKLKDA 476
Cdd:COG1196 313 ----ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA---------------EAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 477 LIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAmvtQLTDKNFNMEER 556
Cdd:COG1196 374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE---EEEEALEEAAEE 450
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 392900641 557 IMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLK 596
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
452-685 |
7.36e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.92 E-value: 7.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 452 GGAAQVGNSVQMKQIEIqnDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQE 531
Cdd:TIGR02168 663 GGSAKTNSSILERRREI--EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 532 QIDAAmgaEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNG------- 604
Cdd:TIGR02168 741 EVEQL---EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAeltllne 817
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 605 --------------RIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLhghISVDNDRASMvnQLQISAN 670
Cdd:TIGR02168 818 eaanlrerleslerRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL---EALLNERASL--EEALALL 892
|
250
....*....|....*
gi 392900641 671 RNFAEDVERQVNAIE 685
Cdd:TIGR02168 893 RSELEELSEELRELE 907
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
317-594 |
2.43e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.00 E-value: 2.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRVSFELRsseevrsrliQKITELEKQIgdeRIAKEQLQAWQDENK 396
Cdd:TIGR02168 253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA----------NEISRLEQQK---QILRERLANLERQLE 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 397 VLlsdhQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANgggaAQVGNSVQMKQIEIQNDKLKDA 476
Cdd:TIGR02168 320 EL----EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE----LESRLEELEEQLETLRSKVAQL 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 477 LIKLRDLNAQatldRQKAVDEAERLKTENSELIrvAENLKRQTEIAESKIAGFQEQIDaamGAEAMVTQLTDKNFNMEER 556
Cdd:TIGR02168 392 ELQIASLNNE----IERLEARLERLEDRRERLQ--QEIEELLKKLEEAELKELQAELE---ELEEELEELQEELERLEEA 462
|
250 260 270
....*....|....*....|....*....|....*...
gi 392900641 557 IMQLEETIEDMEEARDLDEQLAEvQKQQVKDLMKEIEQ 594
Cdd:TIGR02168 463 LEELREELEEAEQALDAAERELA-QLQARLDSLERLQE 499
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
317-646 |
2.70e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 61.98 E-value: 2.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRVSFELRSS-EEVRSRLiqKITELEKQIGDERIA-----KEQLQA 390
Cdd:PRK02224 251 EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEErDDLLAEA--GLDDADAEAVEARREeledrDEELRD 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 391 WQDENKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESM-------ETELEILKEEMANGggAAQVGNS-VQ 462
Cdd:PRK02224 329 RLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAreavedrREEIEELEEEIEEL--RERFGDApVD 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 463 MKQIEIQNDKLKDALIKLRDLNAQATLDRQ---KAVDEAERL-----------KTENSELIRVAENLKRQTEIAESKIAG 528
Cdd:PRK02224 407 LGNAEDFLEELREERDELREREAELEATLRtarERVEEAEALleagkcpecgqPVEGSPHVETIEEDRERVEELEAELED 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 529 FQEQIDA----------AMGAEAMVTQLTDKNFNMEERIMQLEETIEDM--------EEARDLDEQlAEVQKQQVKDLMK 590
Cdd:PRK02224 487 LEEEVEEveerleraedLVEAEDRIERLEERREDLEELIAERRETIEEKreraeelrERAAELEAE-AEEKREAAAEAEE 565
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 392900641 591 EIEQLKIHIHELNG-------------RIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEE 646
Cdd:PRK02224 566 EAEEAREEVAELNSklaelkeriesleRIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRE 634
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
318-607 |
3.77e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.61 E-value: 3.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRvsfELRSSEEvrsrliqKITELEKQIGDeriAKEQLQAWQDENKV 397
Cdd:TIGR02168 226 ELALLVLRLEELREELEELQEELKEAEEELEELTA---ELQELEE-------KLEELRLEVSE---LEEEIEELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 398 LLSDhQDTMEMatiEKELAEERADSLQNDVLTLTEKLESMETELEILKEEmangggAAQVGNSVQMKQIEIQ-------- 469
Cdd:TIGR02168 293 LANE-ISRLEQ---QKQILRERLANLERQLEELEAQLEELESKLDELAEE------LAELEEKLEELKEELEsleaelee 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 470 -NDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRvaenLKRQTEIAESKIAGFQEQIdaamgaEAMVTQLTD 548
Cdd:TIGR02168 363 lEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER----LEARLERLEDRRERLQQEI------EELLKKLEE 432
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 549 KNFN-MEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIR 607
Cdd:TIGR02168 433 AELKeLQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
5-101 |
5.14e-09 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 60.85 E-value: 5.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 5 IGTRVKTSSGNGRVVFCGQTQFAEGDWVGVILDTATGKNNGTVQNVQYFECEPNFGVFVKssaveledASKRSGLKAPAA 84
Cdd:COG5244 6 VNDRVLLGDKFGTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIR--------PDDDSLLNGNAA 77
|
90
....*....|....*..
gi 392900641 85 SAIRKDSSVMSRSAGSK 101
Cdd:COG5244 78 YEKIKGGLVCESKGMDK 94
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
322-1154 |
5.16e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.23 E-value: 5.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 322 LRNQVKELTEKLEAARVKRKEDhtkvmELDRVSFELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDENKVLLSD 401
Cdd:TIGR02168 218 LKAELRELELALLVLRLEELRE-----ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 402 HQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEmangggAAQVGNSVQMKQIEIQ---------NDK 472
Cdd:TIGR02168 293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE------LAELEEKLEELKEELEsleaeleelEAE 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 473 LKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRvaenLKRQTEIAESKIAGFQEQIdaamgaEAMVTQLTDKNFN 552
Cdd:TIGR02168 367 LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER----LEARLERLEDRRERLQQEI------EELLKKLEEAELK 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 553 -MEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRirdeqkhavdlsqtiLKFRERMANLN 631
Cdd:TIGR02168 437 eLQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR---------------LDSLERLQENL 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 632 SQIQDQKDQVLSLEEQLHGH-------ISVDND-RASMVNQLQISANRNFAEDVERQVNAIEveFARRQAGYLKAFLP-- 701
Cdd:TIGR02168 502 EGFSEGVKALLKNQSGLSGIlgvlselISVDEGyEAAIEAALGGRLQAVVVENLNAAKKAIA--FLKQNELGRVTFLPld 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 702 ---------DNFSRVGGENDSILLVVMLPRLAAK-TKLFASLAAQCF------------PQVPGGMRreHVTKshKGEQW 759
Cdd:TIGR02168 580 sikgteiqgNDREILKNIEGFLGVAKDLVKFDPKlRKALSYLLGGVLvvddldnalelaKKLRPGYR--IVTL--DGDLV 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 760 AHVARVNYLANSINAALGKLESAIGETTVEVLI---KLTETYGEMSTHEKTVDQYLELLKKSRFDENTSLDSFvrplvyf 836
Cdd:TIGR02168 656 RPGGVITGGSAKTNSSILERRREIEELEEKIEEleeKIAELEKALAELRKELEELEEELEQLRKELEELSRQI------- 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 837 qnmfslhiggdgfnaahwvSEICASLSAGLAYCRVNTQRISyflQESITAGEVYNMLQTLNDEFAACESVILKAyrllpg 916
Cdd:TIGR02168 729 -------------------SALRKDLARLEAEVEQLEERIA---QLSKELTELEAEIEELEERLEEAEEELAEA------ 780
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 917 nvsgsEQKILKLESEFtEDLLNSVVQLDKMVSILQEVCANGALSFGGISETEGFDEKRVKEminavlgKQDGYIAIDKTF 996
Cdd:TIGR02168 781 -----EAEIEELEAQI-EQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAA-------TERRLEDLEEQI 847
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 997 DPIRALIKSLRDSLEKVNSTLE--SAKMEHSAPEKKSFPPLLDRAHHRKQAAQEaeglrwQMEKKDNEMLELRKQMKARI 1074
Cdd:TIGR02168 848 EELSEDIESLAAEIEELEELIEelESELEALLNERASLEEALALLRSELEELSE------ELRELESKRSELRRELEELR 921
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 1075 EDVSNYKLRLDMAESRLNstdkaegdkvkHLEEKINQmvadhrrkqiEYDESMDALQREMKEVESDNLELKQRANKISKE 1154
Cdd:TIGR02168 922 EKLAQLELRLEGLEVRID-----------NLQERLSE----------EYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
357-1311 |
2.23e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.91 E-value: 2.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 357 LRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDENKvllsdhqdtmEMATIEKELAEERADSLQNDVLTLTEKLES 436
Cdd:TIGR02168 181 LERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKA----------ELRELELALLVLRLEELREELEELQEELKE 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 437 METELEILKEEMANGGGA---AQVGNSVQMKQIEIQNDKLKDALIKLRDLNAQAtldrQKAVDEAERLKTENSELIRVAE 513
Cdd:TIGR02168 251 AEEELEELTAELQELEEKleeLRLEVSELEEEIEELQKELYALANEISRLEQQK----QILRERLANLERQLEELEAQLE 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 514 NLKRQTEIAESKIAGFQEQIDAAM----GAEAMVTQLTDKNFNMEERIMQLEETIEdmEEARDLDEQlaevqKQQVKDLM 589
Cdd:TIGR02168 327 ELESKLDELAEELAELEEKLEELKeeleSLEAELEELEAELEELESRLEELEEQLE--TLRSKVAQL-----ELQIASLN 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 590 KEIEQLKIHIHELNGRIRDeqkhavdLSQTILKFRERMANlnSQIQDQKDQVLSLEEQLHGHISvdnDRASMVNQLQISA 669
Cdd:TIGR02168 400 NEIERLEARLERLEDRRER-------LQQEIEELLKKLEE--AELKELQAELEELEEELEELQE---ELERLEEALEELR 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 670 NRnfAEDVERQVNAIEVEFARRQAgyLKAFLPDNFSRVGGENDSIllvvmlprlaAKTKLFASLAAQCFPQVPGGMRREh 749
Cdd:TIGR02168 468 EE--LEEAEQALDAAERELAQLQA--RLDSLERLQENLEGFSEGV----------KALLKNQSGLSGILGVLSELISVD- 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 750 vtkshkgEQWAhvarvnylaNSINAALGKLESAIgettvevlikLTETygemsthEKTVDQYLELLKKSRFDENT--SLD 827
Cdd:TIGR02168 533 -------EGYE---------AAIEAALGGRLQAV----------VVEN-------LNAAKKAIAFLKQNELGRVTflPLD 579
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 828 SFVRPLVYFQNMFSLHIGGDGFNAAHWVSEICASLSAGLAY----CRV-------NTQRISYFLQESITagevynmlqTL 896
Cdd:TIGR02168 580 SIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggVLVvddldnaLELAKKLRPGYRIV---------TL 650
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 897 NDEFAACESVILKAYRLLPGNVSGSEQKILKLESEFtEDLLNSVVQLDKMVSILqevcangalsfggisetegfdEKRVK 976
Cdd:TIGR02168 651 DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKI-EELEEKIAELEKALAEL---------------------RKELE 708
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 977 EMINAVLGKQDGYIAIDKTFDPIRALIKSLRDSLEKVNSTLESAKMEhsapekksfppLLDRAHHRKQAAQEAEGLRWQM 1056
Cdd:TIGR02168 709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEIEELEERLEEAEEEL 777
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 1057 EKKDNEMLELRKQMKARIEDVSNYKLRLDMAESRLNSTDKAEGDkvkhLEEKINQMVADHRRKQIEYDESMDALQREMKE 1136
Cdd:TIGR02168 778 AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN----LRERLESLERRIAATERRLEDLEEQIEELSED 853
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 1137 VESDNLELKQ---RANKISKE-ALWKNIQSMETRSSGSPSVPMSTSIDEGGASRGEVVFLENQLNKQTNARKRAELEVRK 1212
Cdd:TIGR02168 854 IESLAAEIEEleeLIEELESElEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 1213 LKGELAQ-------AGSKRFSAVPGLISGPITLESQTRQDL--LLKLIDNLHD---------ESLRLRREEVNHQAYVPS 1274
Cdd:TIGR02168 934 LEVRIDNlqerlseEYSLTLEEAEALENKIEDDEEEARRRLkrLENKIKELGPvnlaaieeyEELKERYDFLTAQKEDLT 1013
|
970 980 990
....*....|....*....|....*....|....*..
gi 392900641 1275 NPKISTEKMVEEMEIfnVKREQFFDKLNSVNRRLRRV 1311
Cdd:TIGR02168 1014 EAKETLEEAIEEIDR--EARERFKDTFDQVNENFQRV 1048
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
346-646 |
8.35e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 57.00 E-value: 8.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 346 KVMELDRVSFELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDEnkvLLSDHQDTMEMATIEKELAEERA--DSL 423
Cdd:PRK03918 153 QILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKE---LEEVLREINEISSELPELREELEklEKE 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 424 QNDVLTLTEKLESMETELEILKEEMAngggaaqvGNSVQMKQIEIQNDKLKDALIKLRDLNAQATLDRQKAvDEAERLKT 503
Cdd:PRK03918 230 VKELEELKEEIEELEKELESLEGSKR--------KLEEKIRELEERIEELKKEIEELEEKVKELKELKEKA-EEYIKLSE 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 504 ENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKq 583
Cdd:PRK03918 301 FYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKK- 379
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 392900641 584 qvKDLMKEIEQLKIHIHELngrirdeQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEE 646
Cdd:PRK03918 380 --RLTGLTPEKLEKELEEL-------EKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK 433
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
353-584 |
9.56e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.93 E-value: 9.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 353 VSFELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTE 432
Cdd:COG4942 11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 433 KLESMETELEILKEEMANGGGAAQVGNSVQMKQIEIQNDKLKDALIKLRDLNAQATLDRQkavdEAERLKTENSELIRVA 512
Cdd:COG4942 91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEELRADLAELAALR 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 392900641 513 ENLKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKnfnMEERIMQLEETIEDM-EEARDLDEQLAEVQKQQ 584
Cdd:COG4942 167 AELEAERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELqQEAEELEALIARLEAEA 236
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
319-588 |
1.09e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 56.59 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 319 IEYLRNQVKELTEKLEAARVKR---KEDHTKVMELDRVSFELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDEN 395
Cdd:PRK02224 470 IEEDRERVEELEAELEDLEEEVeevEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAEL 549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 396 KVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILkEEMANGGGAAQVGNSvQMKQIEIQNDKLKD 475
Cdd:PRK02224 550 EAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLL-AAIADAEDEIERLRE-KREALAELNDERRE 627
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 476 ALIKLRDLNAQAtldrQKAVDEAeRLKTENSELIRVAENLkrqtEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEE 555
Cdd:PRK02224 628 RLAEKRERKREL----EAEFDEA-RIEEAREDKERAEEYL----EQVEEKLDELREERDDLQAEIGAVENELEELEELRE 698
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 392900641 556 RIMQLEETIEDMEEARDLDEQL--------AEVQKQQVKDL 588
Cdd:PRK02224 699 RREALENRVEALEALYDEAEELesmygdlrAELRQRNVETL 739
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
318-607 |
1.42e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.22 E-value: 1.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDR----VSFELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQD 393
Cdd:TIGR02168 783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 394 ENKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETEleilkeemangggaaqvgnsvqmkqieiqNDKL 473
Cdd:TIGR02168 863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK-----------------------------RSEL 913
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 474 KDALIKLRDLNAQATLDRQKAvdeaerlktenseLIRVAENLKRQTEiaeskiagfqEQIDAAMGAEAMVTQLTDKNFNM 553
Cdd:TIGR02168 914 RRELEELREKLAQLELRLEGL-------------EVRIDNLQERLSE----------EYSLTLEEAEALENKIEDDEEEA 970
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392900641 554 EERIMQLEETIED--------MEEARDLDEQLAEVqKQQVKDLMKEIEQLKIHIHELNGRIR 607
Cdd:TIGR02168 971 RRRLKRLENKIKElgpvnlaaIEEYEELKERYDFL-TAQKEDLTEAKETLEEAIEEIDREAR 1031
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
323-647 |
1.56e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 55.80 E-value: 1.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 323 RNQVKELTEKLEAARVKRKEDHTKVMELDRVSFELRSS-EEVRSRLIQKITELEK------QIGDERI-AKEQLQAWQ-- 392
Cdd:TIGR04523 196 LLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNiEKKQQEINEKTTEISNtqtqlnQLKDEQNkIKKQLSEKQke 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 393 -DENKVLLSDHQDtmEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANgggaaqvgNSVQMKQIEIQND 471
Cdd:TIGR04523 276 lEQNNKKIKELEK--QLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQ--------NNKIISQLNEQIS 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 472 KLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIagfQEQidaamgaeamvtqlTDKNF 551
Cdd:TIGR04523 346 QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKI---QNQ--------------EKLNQ 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 552 NMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLN 631
Cdd:TIGR04523 409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQ 488
|
330
....*....|....*.
gi 392900641 632 SQIQDQKDQVLSLEEQ 647
Cdd:TIGR04523 489 KELKSKEKELKKLNEE 504
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
366-648 |
2.16e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 55.43 E-value: 2.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 366 RLIQKITELEKQIGDERIAKEQLQAWQDENKVLLSDHQDTM-EMATIEKELAEERAD---------SLQNDVLTLTEKLE 435
Cdd:PRK02224 210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERReELETLEAEIEDLRETiaeterereELAEEVRDLRERLE 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 436 SMETELEILKEEMANGGGAAqvgnsvqmKQIEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAER-------LKTENSEL 508
Cdd:PRK02224 290 ELEEERDDLLAEAGLDDADA--------EAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESlredaddLEERAEEL 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 509 IRVAENLKRQTEIAESKIAGFQEQIDAamgaeamvtqltdknfnMEERIMQLEETIEDMEEARD-LDEQLAEVQ------ 581
Cdd:PRK02224 362 REEAAELESELEEAREAVEDRREEIEE-----------------LEEEIEELRERFGDAPVDLGnAEDFLEELReerdel 424
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 392900641 582 KQQVKDLMKEIEQLKIHIHElNGRIRDEQK------------HAvdlsQTILKFRERMANLNSQIQDQKDQVLSLEEQL 648
Cdd:PRK02224 425 REREAELEATLRTARERVEE-AEALLEAGKcpecgqpvegspHV----ETIEEDRERVEELEAELEDLEEEVEEVEERL 498
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
317-647 |
2.47e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.16 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAARvKRKEDHTKVMELDRVSFELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDE-- 394
Cdd:COG4717 102 EELEELEAELEELREELEKLE-KLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEEle 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 395 ---------NKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEE------------------ 447
Cdd:COG4717 181 elleqlslaTEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEerlkearlllliaaalla 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 448 ------------------MANGGGAAQVGNSVQMKQiEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELI 509
Cdd:COG4717 261 llglggsllsliltiagvLFLVLGLLALLFLLLARE-KASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEEL 339
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 510 RVAENLKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEE----RIMQLEETIEDMEEARDLDEQLAE------ 579
Cdd:COG4717 340 LELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEelraALEQAEEYQELKEELEELEEQLEEllgele 419
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392900641 580 --VQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTI--LKFRERMANLNSQIQDQKDQVLSLEEQ 647
Cdd:COG4717 420 elLEALDEEELEEELEELEEELEELEEELEELREELAELEAELeqLEEDGELAELLQELEELKAELRELAEE 491
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
317-648 |
4.05e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 54.64 E-value: 4.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAARVKRKEDHTKvmeldRVSFELRSSEEvrsrliqKITELEKQIgderiakeqlqawqDENK 396
Cdd:TIGR04523 281 KKIKELEKQLNQLKSEISDLNNQKEQDWNK-----ELKSELKNQEK-------KLEEIQNQI--------------SQNN 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 397 VLLSDHQDTMEmaTIEKELaeeraDSLQNDVLTLTEKLESMETELEILKEEmangggaaQVGNSVQMKQIEIQNDKLKDA 476
Cdd:TIGR04523 335 KIISQLNEQIS--QLKKEL-----TNSESENSEKQRELEEKQNEIEKLKKE--------NQSYKQEIKNLESQINDLESK 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 477 LIKLRDLNAQatLDRQkavdeAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIdaamgaeamvTQLTDKNFNMEER 556
Cdd:TIGR04523 400 IQNQEKLNQQ--KDEQ-----IKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQD----------SVKELIIKNLDNT 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 557 IMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQD 636
Cdd:TIGR04523 463 RESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISD 542
|
330
....*....|..
gi 392900641 637 QKDQVLSLEEQL 648
Cdd:TIGR04523 543 LEDELNKDDFEL 554
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
332-649 |
4.89e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 54.26 E-value: 4.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 332 KLEAARVKRKEDHTKVM-ELDRVSFELRSSEEVRSRLIQKITELE-----------------KQIGDERIAKEQ----LQ 389
Cdd:TIGR04523 128 KLEKQKKENKKNIDKFLtEIKKKEKELEKLNNKYNDLKKQKEELEnelnllekeklniqkniDKIKNKLLKLELllsnLK 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 390 AWQDENKVLLSDhqdTMEMATIEKELaEERADSLQNDVLTLTEKLESMETELEILKEEMANgggaaqVGNSVQMKQIEIQ 469
Cdd:TIGR04523 208 KKIQKNKSLESQ---ISELKKQNNQL-KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNK------IKKQLSEKQKELE 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 470 --NDKLKDALIKLRDLNAQ-ATLDRQKavdEAERLKTENSELirvaENLKRQTEIAESKIAGFQEQIDaamgaeamvtQL 546
Cdd:TIGR04523 278 qnNKKIKELEKQLNQLKSEiSDLNNQK---EQDWNKELKSEL----KNQEKKLEEIQNQISQNNKIIS----------QL 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 547 TDKnfnmeerIMQLEETIEDME-EARDLDEQLAEvQKQQVKDLMKEIEQLKIHIHELNGRIRDeqkhavdlsqtilkfre 625
Cdd:TIGR04523 341 NEQ-------ISQLKKELTNSEsENSEKQRELEE-KQNEIEKLKKENQSYKQEIKNLESQIND----------------- 395
|
330 340
....*....|....*....|....
gi 392900641 626 rmanLNSQIQDQKDQVLSLEEQLH 649
Cdd:TIGR04523 396 ----LESKIQNQEKLNQQKDEQIK 415
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
318-596 |
5.17e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.30 E-value: 5.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAARVKRKEDHTkvmELDRVSFELRSSEEVRSRLIQKITELEKQIGDERIAK--EQLQAWQDEN 395
Cdd:TIGR02169 731 EEEKLKERLEELEEDLSSLEQEIENVKS---ELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiqAELSKLEEEV 807
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 396 KVL---LSDHQDTMEMATIEKELAEERADSLQNDVLTLTEK-------LESMETELEILKEEMANGGGA-AQVGNSVQ-- 462
Cdd:TIGR02169 808 SRIearLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQiksiekeIENLNGKKEELEEELEELEAAlRDLESRLGdl 887
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 463 MKQIEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEI--AESKIAGFQEQIDAamgae 540
Cdd:TIGR02169 888 KKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpeEELSLEDVQAELQR----- 962
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 392900641 541 amvtqltdknfnMEERIMQLEE----TIEDMEEAR----DLDEQLA--EVQKQQVKDLMKEIEQLK 596
Cdd:TIGR02169 963 ------------VEEEIRALEPvnmlAIQEYEEVLkrldELKEKRAklEEERKAILERIEEYEKKK 1016
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
317-584 |
7.37e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.92 E-value: 7.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAARVKRKEDhTKVMELDRVSFELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDENK 396
Cdd:TIGR02169 285 GEEEQLRVKEKIGELEAEIASLERSIA-EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 397 vllsdhqdtMEMATIEKELAEERADSLqndvlTLTEKLESMETELEILKEEMangggaaqvgNSVQMKQIEIQnDKLKDA 476
Cdd:TIGR02169 364 ---------EELEDLRAELEEVDKEFA-----ETRDELKDYREKLEKLKREI----------NELKRELDRLQ-EELQRL 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 477 LIKLRDLNAqatldrqkavdEAERLKTENSELIRVAENLKRQTEIAESKIagfqEQIDAAMGAEamvtqltdknfnmEER 556
Cdd:TIGR02169 419 SEELADLNA-----------AIAGIEAKINELEEEKEDKALEIKKQEWKL----EQLAADLSKY-------------EQE 470
|
250 260
....*....|....*....|....*....
gi 392900641 557 IMQLEETIEDME-EARDLDEQLAEVQKQQ 584
Cdd:TIGR02169 471 LYDLKEEYDRVEkELSKLQRELAEAEAQA 499
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
370-648 |
1.71e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 52.52 E-value: 1.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 370 KITELEKQIgdeRIAKEQLQAWQDENKVLLSDHQDTMEmatiEKELAEERADSLQNDVLTLTEKLESMETELEILK---E 446
Cdd:pfam10174 241 KISSLERNI---RDLEDEVQMLKTNGLLHTEDREEEIK----QMEVYKSHSKFMKNKIDQLKQELSKKESELLALQtklE 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 447 EMANGggaaqvgNSVQMKQIEIQNDKLK-------------DALiKLRDLNAQATLDrqKAVDEAERLKTENSELIRVAE 513
Cdd:pfam10174 314 TLTNQ-------NSDCKQHIEVLKESLTakeqraailqtevDAL-RLRLEEKESFLN--KKTKQLQDLTEEKSTLAGEIR 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 514 NLKRQTEIAESKIAGFQEQI----------DAAMGA--EAMVTQLTDKN------FNMEERIMQLEETIEDMEEARDLDE 575
Cdd:pfam10174 384 DLKDMLDVKERKINVLQKKIenlqeqlrdkDKQLAGlkERVKSLQTDSSntdtalTTLEEALSEKERIIERLKEQRERED 463
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392900641 576 Q--LAEVQ--KQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQL 648
Cdd:pfam10174 464 RerLEELEslKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQL 540
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
71-306 |
3.11e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.25 E-value: 3.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 71 EDASKRSGLKAPAASAIRKDSSVmsrsagskasPGSSPGMSPAASSEKLTGRQTGMGPRSMSKLAdPNEKKRSTTPQKAR 150
Cdd:PHA03247 2546 DDAGDPPPPLPPAAPPAAPDRSV----------PPPRPAPRPSEPAVTSRARRPDAPPQSARPRA-PVDDRGDPRGPAPP 2614
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 151 SPAPPMTKK-NSESTSRMVREFSNLSQSSVASSRASASASKPRPQFTAPDPRRQSLAPPKKASTTTAPVSKPSLSKPRQS 229
Cdd:PHA03247 2615 SPLPPDTHApDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS 2694
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392900641 230 LAPSKPAEVTPQKPVPAAQASEAGdppneLPLPTMTESGTELPKESVLSRAKKIDDTGPAAPMSPlstTAAARPRTT 306
Cdd:PHA03247 2695 LTSLADPPPPPPTPEPAPHALVSA-----TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGP---ARPARPPTT 2763
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
327-641 |
3.86e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 51.56 E-value: 3.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 327 KELTEKLEAARVKRKEDHTKVMELDrvsfELRSSEEVRSRLIQKITELEKQIgderiaKEQLQAWQDENKVLLSDHQD-- 404
Cdd:TIGR04523 363 RELEEKQNEIEKLKKENQSYKQEIK----NLESQINDLESKIQNQEKLNQQK------DEQIKKLQQEKELLEKEIERlk 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 405 ---TMEMATIeKELAEERAdSLQNDVLTLTEKLESMETELEILKEEMangggaaqvgNSVQMKQiEIQNDKLKDALIKLR 481
Cdd:TIGR04523 433 etiIKNNSEI-KDLTNQDS-VKELIIKNLDNTRESLETQLKVLSRSI----------NKIKQNL-EQKQKELKSKEKELK 499
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 482 DLNAQATLDRQKAVDeaerLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAaMGAEAMVTQLTDKNFNMEERIMQLE 561
Cdd:TIGR04523 500 KLNEEKKELEEKVKD----LTKKISSLKEKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKEIEELK 574
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 562 ETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQV 641
Cdd:TIGR04523 575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
191-303 |
4.03e-06 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 50.24 E-value: 4.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 191 PRPQFTAPDPRRQSLAPPKKASTTTAPVSKPSLSKPRQSLAPSKPAEVTPQKPVPAAQASEAGDPPNElPLPTMTESGTE 270
Cdd:PHA02682 84 PSPACAAPAPACPACAPAAPAPAVTCPAPAPACPPATAPTCPPPAVCPAPARPAPACPPSTRQCPPAP-PLPTPKPAPAA 162
|
90 100 110
....*....|....*....|....*....|...
gi 392900641 271 LPkeSVLSRAKKIDDTgPAAPMSPLSTTAAARP 303
Cdd:PHA02682 163 KP--IFLHNQLPPPDY-PAASCPTIETAPAASP 192
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
431-608 |
4.35e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.45 E-value: 4.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 431 TEKLESMETELEILKEEMANGGGAAQvgnsvQMKQIEIQNDKLKDALIKLRDLN--------AQATLDRQKavDEAERLK 502
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLE-----ALEAELDALQERREALQRLAEYSwdeidvasAEREIAELE--AELERLD 681
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 503 TENSELirvaENLKRQTEIAESKIAGFQEQIDAAMGAEAmvtQLTDKNFNMEERIMQLEETIEDMEEAR------DLDEQ 576
Cdd:COG4913 682 ASSDDL----AALEEQLEELEAELEELEEELDELKGEIG---RLEKELEQAEEELDELQDRLEAAEDLArlelraLLEER 754
|
170 180 190
....*....|....*....|....*....|....*..
gi 392900641 577 LAE-----VQKQQVKDLMKEIEQLKIHIHELNGRIRD 608
Cdd:COG4913 755 FAAalgdaVERELRENLEERIDALRARLNRAEEELER 791
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
324-648 |
4.65e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.92 E-value: 4.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 324 NQVKELTEKLEAARVKRKEDHTKVMELDRVSFELRSSEEVRSRLIQKITELEKQIGDERI------AKEQLQAWQDENKV 397
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqeleaLEAELAELPERLEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 398 LLSDHQDT----MEMATIEKELAEERAD----------SLQNDVLTLTEKLESMETELEILKEEMAN-----GGGAAQVG 458
Cdd:COG4717 151 LEERLEELreleEELEELEAELAELQEEleelleqlslATEEELQDLAEELEELQQRLAELEEELEEaqeelEELEEELE 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 459 NSVQMKQIEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVA-----------ENLKRQTEIAESKIA 527
Cdd:COG4717 231 QLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGllallflllarEKASLGKEAEELQAL 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 528 GFQEQIDAAMGAEamvtQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQ-QVKDLMKEIEQLkihIHELNGRI 606
Cdd:COG4717 311 PALEELEEEELEE----LLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEElQLEELEQEIAAL---LAEAGVED 383
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 392900641 607 RDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQL 648
Cdd:COG4717 384 EEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL 425
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
325-680 |
4.86e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.30 E-value: 4.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 325 QVKELTEKLEAARVKRKEDHTKVMELDRVSFELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDENKVLlsdhQD 404
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMAL----RK 1582
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 405 TMEMATIEKELAEERADSLQNDVLTLTEKLESMETE---LEILK--EEMANGGGAAQVGNSVQMKQIEIQNDKLKDALIK 479
Cdd:PTZ00121 1583 AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAkikAEELKkaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 480 LRDLNAQATLDRQKavdeAERLKTENSELIRVAENLKRQTEiaESKIAgfqEQIDAAMGAEAMVTQLTDKnfNMEERIMQ 559
Cdd:PTZ00121 1663 AAEEAKKAEEDKKK----AEEAKKAEEDEKKAAEALKKEAE--EAKKA---EELKKKEAEEKKKAEELKK--AEEENKIK 1731
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 560 LEETIEDMEEARDLDEQLA--EVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDlsqtilkfRERMANLNSQIQDQ 637
Cdd:PTZ00121 1732 AEEAKKEAEEDKKKAEEAKkdEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEED--------EKRRMEVDKKIKDI 1803
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 392900641 638 KDQVLSLEEQLHGHISVDNDRASM----VNQLQISAN--RNFAEDVERQ 680
Cdd:PTZ00121 1804 FDNFANIIEGGKEGNLVINDSKEMedsaIKEVADSKNmqLEEADAFEKH 1852
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
317-595 |
4.99e-06 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 49.91 E-value: 4.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRvsfELRSSEEVRSRLIQKITELeKQIGDERIAK-----EQLQAW 391
Cdd:COG1340 22 EEIEELKEKRDELNEELKELAEKRDELNAQVKELRE---EAQELREKRDELNEKVKEL-KEERDELNEKlnelrEELDEL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 392 QDENKVLlsdHQDTMEMATIEKELAEERaDSLQNDVLT------LTEKLESMETELEILKEEmangggaaqvgnsvqmkq 465
Cdd:COG1340 98 RKELAEL---NKAGGSIDKLRKEIERLE-WRQQTEVLSpeeekeLVEKIKELEKELEKAKKA------------------ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 466 iEIQNDKLKDALIKLRDLNAQATLDRQK---AVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDaamgaeam 542
Cdd:COG1340 156 -LEKNEKLKELRAELKELRKEAEEIHKKikeLAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKAD-------- 226
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 392900641 543 vtQLTDKNFNMEERIMQLEETIEDMEE-----ARDLDEQLAEVQKQQVKDLMKEIEQL 595
Cdd:COG1340 227 --ELHEEIIELQKELRELRKELKKLRKkqralKREKEKEELEEKAEEIFEKLKKGEKL 282
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
73-300 |
1.14e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 50.32 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 73 ASKRSGLKAPAASAIRKDSSVMSRSAGSKASP---GSSPGMSPAASSEKLTGRQTGMGPR--SMSKLADPNEkkrsttPQ 147
Cdd:PHA03247 2632 SPAANEPDPHPPPTVPPPERPRDDPAPGRVSRprrARRLGRAAQASSPPQRPRRRAARPTvgSLTSLADPPP------PP 2705
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 148 KARSPAPPMTKKNSESTSRMVREFSNLSQSSVASSRASASASKPRPQFTAPDPRRQSLAPPKKASTTTAPVSKPSLSKPR 227
Cdd:PHA03247 2706 PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTR 2785
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 392900641 228 QSLAPSKPAEVTPQKPVPAAQASEAGDPPNELPLPTMTESGTELPKESVLSrakkiddTGPAAPMSPLSTTAA 300
Cdd:PHA03247 2786 PAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP-------TAPPPPPGPPPPSLP 2851
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
417-692 |
1.29e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 49.63 E-value: 1.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 417 EERADSLQNDVLTLTEKLESMETELEILK----------------EEMANGGGAAQVGNSVQmKQIEIQNDKLKDAL-IK 479
Cdd:COG3206 63 PQSSDVLLSGLSSLSASDSPLETQIEILKsrpvlervvdklnldeDPLGEEASREAAIERLR-KNLTVEPVKGSNVIeIS 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 480 LRDLNAQATLDRQKAVDEA---ERLKTENSELIRVAENLKRQTEI-------AESKIAGFQEQ---IDAAMGAEAMVTQL 546
Cdd:COG3206 142 YTSPDPELAAAVANALAEAyleQNLELRREEARKALEFLEEQLPElrkeleeAEAALEEFRQKnglVDLSEEAKLLLQQL 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 547 TDknfnMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMK--EIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFR 624
Cdd:COG3206 222 SE----LESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARYTPNHPDVIALR 297
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 392900641 625 ERMANLNSQIQDQKDQVLsleeqlhghISVDNDRASMVNQLQ-ISANRNFAEDVERQVNAIEVEFARRQ 692
Cdd:COG3206 298 AQIAALRAQLQQEAQRIL---------ASLEAELEALQAREAsLQAQLAQLEARLAELPELEAELRRLE 357
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
319-592 |
1.35e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.91 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 319 IEYLRNQVKELTEKLEAAR-------------VKRKEDHTKVMELDRVSFELRSSEEVRSRLIQKITELEKQIGDERIAK 385
Cdd:COG4913 612 LAALEAELAELEEELAEAEerlealeaeldalQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALE 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 386 EQLQAWQDEnkvlLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESME----TELEILKEEMANGGGAAQVGNSV 461
Cdd:COG4913 692 EQLEELEAE----LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEdlarLELRALLEERFAAALGDAVEREL 767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 462 QmKQIEIQNDKLKDALIKLRD--LNAQATLDRQ------------KAVDEAERL--KTENSELIRVAENLKRQ-TEIAES 524
Cdd:COG4913 768 R-ENLEERIDALRARLNRAEEelERAMRAFNREwpaetadldadlESLPEYLALldRLEEDGLPEYEERFKELlNENSIE 846
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 525 KIAGFQEQIDAamgAEAMVTQ--------LTDKNFNmEERIMQLEETIEDMEEARDL--------------DEQLAEVQK 582
Cdd:COG4913 847 FVADLLSKLRR---AIREIKEridplndsLKRIPFG-PGRYLRLEARPRPDPEVREFrqelravtsgaslfDEELSEARF 922
|
330
....*....|
gi 392900641 583 QQVKDLMKEI 592
Cdd:COG4913 923 AALKRLIERL 932
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
328-635 |
1.63e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 49.12 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 328 ELTEKLEAARVKRKEDHTKVM----ELDRVSFELRSS----EEVRSRLIQKITELEKQIGDERIAKEQLQawqdENKVLL 399
Cdd:pfam07888 45 ELLQAQEAANRQREKEKERYKrdreQWERQRRELESRvaelKEELRQSREKHEELEEKYKELSASSEELS----EEKDAL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 400 SDhqdtmematiEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMangggaaqvgnsvqmkqieiqndklKDALIK 479
Cdd:pfam07888 121 LA----------QRAAHEARIRELEEDIKTLTQRVLERETELERMKERA-------------------------KKAGAQ 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 480 LRDlnaqatldrqkavDEAERLKTENSELIRVAENLKRQTEIAESKiAGFQEQIDAAMGAEAMVTQLTDKNFNMEERIMQ 559
Cdd:pfam07888 166 RKE-------------EEAERKQLQAKLQQTEEELRSLSKEFQELR-NSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 560 LEETIEDMEEARDL---DEQLAEVQKQQVKDL-------MKEIEQLKIHIHELNGRIRDE-----------QKHAVDLSQ 618
Cdd:pfam07888 232 NEALLEELRSLQERlnaSERKVEGLGEELSSMaaqrdrtQAELHQARLQAAQLTLQLADAslalregrarwAQERETLQQ 311
|
330
....*....|....*..
gi 392900641 619 TILKFRERMANLNSQIQ 635
Cdd:pfam07888 312 SAEADKDRIEKLSAELQ 328
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
356-654 |
1.89e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 49.52 E-value: 1.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 356 ELRSSEEVRSRL--IQKITELEkqigderiakeqlqawqDENKVLLSDHQDTMEM-ATIEKelAEERADSLQNDVLTLTE 432
Cdd:PRK11281 34 DLPTEADVQAQLdaLNKQKLLE-----------------AEDKLVQQDLEQTLALlDKIDR--QKEETEQLKQQLAQAPA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 433 KLESMETELEILKEemANGGGAAQVGNSVQMKQIEIQ----NDKLKDALIKLRDLNAQ-ATL----DR-QKAVDEAE--- 499
Cdd:PRK11281 95 KLRQAQAELEALKD--DNDEETRETLSTLSLRQLESRlaqtLDQLQNAQNDLAEYNSQlVSLqtqpERaQAALYANSqrl 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 500 -----RLK--TENSELIRVAENLKRQTEIA--ESKIAgFQEQIDAAMgaeamvTQLTD----KNFNMEERIMQLEETIED 566
Cdd:PRK11281 173 qqirnLLKggKVGGKALRPSQRVLLQAEQAllNAQND-LQRKSLEGN------TQLQDllqkQRDYLTARIQRLEHQLQL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 567 MEEArdLDEQLAEVQKQQVKDLMKEIEQLKIHIHELngrIRDEQKHAVDLSQTILKFRERMANL---NSQIQDQKDQVLS 643
Cdd:PRK11281 246 LQEA--INSKRLTLSEKTVQEAQSQDEAARIQANPL---VAQELEINLQLSQRLLKATEKLNTLtqqNLRVKNWLDRLTQ 320
|
330
....*....|.
gi 392900641 644 LEEQLHGHISV 654
Cdd:PRK11281 321 SERNIKEQISV 331
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
375-584 |
3.20e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.90 E-value: 3.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 375 EKQIGDERIAKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANGGGA 454
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 455 AQV-GNSVQMKQIEIQNDKLKDALIKLRDLNAQATLDRqKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQI 533
Cdd:COG3883 95 LYRsGGSVSYLDVLLGSESFSDFLDRLSALSKIADADA-DLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 392900641 534 DAAMG-AEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQ 584
Cdd:COG3883 174 EAQQAeQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
73-276 |
3.39e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.78 E-value: 3.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 73 ASKRSGLKAPAASAIRKDSSVMSRSAGSKASPgSSPGMSPAASSEKLTGRQTGMGPRSMskLADPnekkrsTTPQKARSP 152
Cdd:PHA03247 2770 APPAAPAAGPPRRLTRPAVASLSESRESLPSP-WDPADPPAAVLAPAAALPPAASPAGP--LPPP------TSAQPTAPP 2840
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 153 APPMTKKNSESTSRMVREFSNLSQSSVASSRASASASKPRPqftapdPRRQSLAPPKKASTTTAPVSKPSLSKPRQSLAP 232
Cdd:PHA03247 2841 PPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARP------PVRRLARPAVSRSTESFALPPDQPERPPQPQAP 2914
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 392900641 233 SKP--AEVTPQKPVPAAQASEAGDPPNELPlPTMTESGTELPKESV 276
Cdd:PHA03247 2915 PPPqpQPQPPPPPQPQPPPPPPPRPQPPLA-PTTDPAGAGEPSGAV 2959
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
462-627 |
4.27e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.46 E-value: 4.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 462 QMKQIEIQNDKLKDALIKLRDlnaqatlDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGA-- 539
Cdd:COG1579 18 ELDRLEHRLKELPAELAELED-------ELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNke 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 540 -EAM---VTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIH-ELNGRIRDEQKHAV 614
Cdd:COG1579 91 yEALqkeIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEaELEELEAEREELAA 170
|
170
....*....|...
gi 392900641 615 DLSQTILKFRERM 627
Cdd:COG1579 171 KIPPELLALYERI 183
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
319-513 |
6.64e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.32 E-value: 6.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 319 IEYLRNQVKELTEKLEAARVKR---KEDHtkvmeldrvsfELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDEN 395
Cdd:COG3206 177 LEFLEEQLPELRKELEEAEAALeefRQKN-----------GLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 396 KVLLSDHQDTM--------------EMATIEKELAEERADSLQN--DVLTLTEKLESMETELEILKEEMANGGGAAQVGN 459
Cdd:COG3206 246 RAQLGSGPDALpellqspviqqlraQLAELEAELAELSARYTPNhpDVIALRAQIAALRAQLQQEAQRILASLEAELEAL 325
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 460 SVQMKQIEIQNDKLKDALIKL-----------RDLNA-----QATLDRQKAVDEAERLKTENSELIRVAE 513
Cdd:COG3206 326 QAREASLQAQLAQLEARLAELpeleaelrrleREVEVarelyESLLQRLEEARLAEALTVGNVRVIDPAV 395
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
321-653 |
8.60e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.26 E-value: 8.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 321 YLRNQvKELTEKLEAARVKRKEDHTKVMELdrvsfelrssEEVRSRLIQKITELEKQIGDERIAKEQLQAwqdenkvlLS 400
Cdd:PRK04863 274 YMRHA-NERRVHLEEALELRRELYTSRRQL----------AAEQYRLVEMARELAELNEAESDLEQDYQA--------AS 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 401 DHQDTMEMATIEKElAEERAdslQNDVLTLTEKLESM-------------------ETELEI--LKEEMANgggaAQVGN 459
Cdd:PRK04863 335 DHLNLVQTALRQQE-KIERY---QADLEELEERLEEQnevveeadeqqeenearaeAAEEEVdeLKSQLAD----YQQAL 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 460 SVQMKQiEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSEL----------IRVAENLKRQTEIAES---KI 526
Cdd:PRK04863 407 DVQQTR-AIQYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEAteellsleqkLSVAQAAHSQFEQAYQlvrKI 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 527 AG----------FQE----------------QIDAAMG-----------AEAMVTQLTDKNFNMEERIMQLEETIEDMEE 569
Cdd:PRK04863 486 AGevsrseawdvAREllrrlreqrhlaeqlqQLRMRLSeleqrlrqqqrAERLLAEFCKRLGKNLDDEDELEQLQEELEA 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 570 AR-DLDEQLAEVQKQQVkDLMKEIEQLKIHIHELN-------------GRIRDEQKHAVDLSQTILKFRERMANLNSQIQ 635
Cdd:PRK04863 566 RLeSLSESVSEARERRM-ALRQQLEQLQARIQRLAarapawlaaqdalARLREQSGEEFEDSQDVTEYMQQLLERERELT 644
|
410
....*....|....*...
gi 392900641 636 DQKDQVLSLEEQLHGHIS 653
Cdd:PRK04863 645 VERDELAARKQALDEEIE 662
|
|
| PspA |
COG1842 |
Phage shock protein A [Transcription, Signal transduction mechanisms]; |
464-596 |
9.43e-05 |
|
Phage shock protein A [Transcription, Signal transduction mechanisms];
Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 45.20 E-value: 9.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 464 KQIEIQNDKLKDALIKLR------------DLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQE 531
Cdd:COG1842 54 KRLERQLEELEAEAEKWEekarlalekgreDLAREALERKAELEAQAEALEAQLAQLEEQVEKLKEALRQLESKLEELKA 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 532 QIDAAMG----AEA------MVTQLTDKNFN-----MEERIMQLE---ETIEDMEEARDLDEQLAEVQKQ-QVKDlmkEI 592
Cdd:COG1842 134 KKDTLKArakaAKAqekvneALSGIDSDDATsalerMEEKIEEMEaraEAAAELAAGDSLDDELAELEADsEVED---EL 210
|
....
gi 392900641 593 EQLK 596
Cdd:COG1842 211 AALK 214
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
318-611 |
9.45e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 46.43 E-value: 9.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAARVKRKEDHTkvmELDRVSFELRSSEEVRSRLIQKITELEKQI----GDERIAKEQLQAWQD 393
Cdd:COG4372 46 ELEQLREELEQAREELEQLEEELEQARS---ELEQLEEELEELNEQLQAAQAELAQAQEELeslqEEAEELQEELEELQK 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 394 ENKVLLSDHQDTME-MATIEKELA--EERADSLQNDVLTLTEKLESMETELEILKEEMANGGGAAQVGNSVQMKQIEIQN 470
Cdd:COG4372 123 ERQDLEQQRKQLEAqIAELQSEIAerEEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEEL 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 471 DKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKN 550
Cdd:COG4372 203 AEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAA 282
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 392900641 551 FNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQK 611
Cdd:COG4372 283 LELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLL 343
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
64-294 |
1.00e-04 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 46.99 E-value: 1.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 64 KSSAVELEDASKRSGL-KAPAASAIRK----DSSVMSRSAG-SKASPGSSPGMSPAASSEKLTGRQTG------------ 125
Cdd:PTZ00449 495 KLAPIEEEDSDKHDEPpEGPEASGLPPkapgDKEGEEGEHEdSKESDEPKEGGKPGETKEGEVGKKPGpakehkpskipt 574
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 126 -----MGPRSMSKLADPNEKKRSTTPQKARSPAPPMTKKNSESTSrmvrefsnlsqsSVASSRASASASKPRpqfTAPDP 200
Cdd:PTZ00449 575 lskkpEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLD------------IPKSPKRPESPKSPK---RPPPP 639
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 201 RRQSlAPPKKASTTTAPVSKPSLSkPRQSLAPS-----------KPAEVTPQKPVPAAQASEAGDPPNELPLPTMTESGT 269
Cdd:PTZ00449 640 QRPS-SPERPEGPKIIKSPKPPKS-PKPPFDPKfkekfyddyldAAAKSKETKTTVVLDESFESILKETLPETPGTPFTT 717
|
250 260
....*....|....*....|....*
gi 392900641 270 ELPKESVLSRAKKIDDTGPAAPMSP 294
Cdd:PTZ00449 718 PRPLPPKLPRDEEFPFEPIGDPDAE 742
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
361-693 |
1.19e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 46.76 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 361 EEVRSRLIQKITELEKQIGDERIAKEQLQAWqdenkvlLSDHQdtmEMATIEKELAEerADSLQNDVltltEKLESMETE 440
Cdd:pfam12128 196 RDVKSMIVAILEDDGVVPPKSRLNRQQVEHW-------IRDIQ---AIAGIMKIRPE--FTKLQQEF----NTLESAELR 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 441 LEILKEEMANgggaAQVGNSVQMKQIEIQNDKLKDALIKLRD----LNAQATLDRqKAVDEAerLKTENSELIRVAENLK 516
Cdd:pfam12128 260 LSHLHFGYKS----DETLIASRQEERQETSAELNQLLRTLDDqwkeKRDELNGEL-SAADAA--VAKDRSELEALEDQHG 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 517 RQTEIAESKIAGFQEQIDaamgaeAMVTQLTdknfNMEERIMQLEETIEDMEEARDLDEQLAevqKQQVKDLMKEIEQLK 596
Cdd:pfam12128 333 AFLDADIETAAADQEQLP------SWQSELE----NLEERLKALTGKHQDVTAKYNRRRSKI---KEQNNRDIAGIKDKL 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 597 IHIHElnGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLHGHIsvDNDRASMVNQLQIsanRNFAED 676
Cdd:pfam12128 400 AKIRE--ARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRL--NQATATPELLLQL---ENFDER 472
|
330
....*....|....*..
gi 392900641 677 VERQVNAIEVEFARRQA 693
Cdd:pfam12128 473 IERAREEQEAANAEVER 489
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
192-305 |
1.89e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 45.86 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 192 RPQFTAPDPRRQSLAPPKKASTTTAPVSKPSLSKPRQSLAPSKPAEVTPQKPVPAAQASEAGDPPNELPLPTMTESGTEL 271
Cdd:PRK14951 383 RPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAI 462
|
90 100 110
....*....|....*....|....*....|....
gi 392900641 272 PKesvlsRAKKIDDTGPAAPMSPLSTTAAARPRT 305
Cdd:PRK14951 463 PV-----RVAPEPAVASAAPAPAAAPAAARLTPT 491
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
416-690 |
2.34e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.68 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 416 AEERADSLQNDVltltEKLESMETELEILKEemangggaaqvgnsvqmkQIEIqndklkdalikLRDLNAQATlDRQKAV 495
Cdd:COG4913 223 TFEAADALVEHF----DDLERAHEALEDARE------------------QIEL-----------LEPIRELAE-RYAAAR 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 496 DEAERLKTENSELirVAENLKRQTEIAESKIAGFQEQIDAAmgaeamvtqltdknfnmEERIMQLEETIEDMEEARD-LD 574
Cdd:COG4913 269 ERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARL-----------------EAELERLEARLDALREELDeLE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 575 EQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLHghisv 654
Cdd:COG4913 330 AQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALE----- 404
|
250 260 270
....*....|....*....|....*....|....*.
gi 392900641 655 dNDRASMVNQLQisanrnfaeDVERQVNAIEVEFAR 690
Cdd:COG4913 405 -EALAEAEAALR---------DLRRELRELEAEIAS 430
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
77-256 |
3.10e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.55 E-value: 3.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 77 SGLKAPAASAIRK-DSSVMSRSAGSKAS-----PGSSPGMSPAASS--EKLTGRQTGMGPRSMSKLADPNEKKRSTTPQK 148
Cdd:PHA03307 223 APGRSAADDAGASsSDSSSSESSGCGWGpenecPLPRPAPITLPTRiwEASGWNGPSSRPGPASSSSSPRERSPSPSPSS 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 149 ARSPAPPMTKKNSESTSRmVREFSnlsqssvassrasasASKPRPQFTAPDPRRQSLAPPkkastttaPVSKPSLSKPRQ 228
Cdd:PHA03307 303 PGSGPAPSSPRASSSSSS-SRESS---------------SSSTSSSSESSRGAAVSPGPS--------PSRSPSPSRPPP 358
|
170 180
....*....|....*....|....*...
gi 392900641 229 SLAPSKPAEVTPQKPVPAAQASEAGDPP 256
Cdd:PHA03307 359 PADPSSPRKRPRPSRAPSSPAASAGRPT 386
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
318-577 |
3.88e-04 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 44.83 E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAarvkrkedhtkvMELDRVSFELRSSEEvrsrliqKITELEKQIGDERIAKEQLqawqDENKV 397
Cdd:PRK04778 257 EIQDLKEQIDENLALLEE------------LDLDEAEEKNEEIQE-------RIDQLYDILEREVKARKYV----EKNSD 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 398 LLSDHQDtmEMATIEKELAEErADSLQN----------DVLTLTEKLESMETELEILKEEMANGGGAA------QVGNSV 461
Cdd:PRK04778 314 TLPDFLE--HAKEQNKELKEE-IDRVKQsytlneseleSVRQLEKQLESLEKQYDEITERIAEQEIAYselqeeLEEILK 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 462 QMKQIEIQNDKLKDALIKLRDlnaqatlDRQKAVDEAERLKTENSELIRVAENLkRQTEIAESKIAGFQEqidAAMGAEA 541
Cdd:PRK04778 391 QLEEIEKEQEKLSEMLQGLRK-------DELEAREKLERYRNKLHEIKRYLEKS-NLPGLPEDYLEMFFE---VSDEIEA 459
|
250 260 270
....*....|....*....|....*....|....*.
gi 392900641 542 MVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQL 577
Cdd:PRK04778 460 LAEELEEKPINMEAVNRLLEEATEDVETLEEETEEL 495
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
318-608 |
4.08e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.93 E-value: 4.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKEltekleaarvkrkedhtkvmeldRVSFELRSSEEVRSRLIQKITELEkqIGDERIAKEQLQAWQDEnkv 397
Cdd:COG1196 562 AIEYLKAAKAG-----------------------RATFLPLDKIRARAALAAALARGA--IGAAVDLVASDLREADA--- 613
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 398 LLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEmanGGGAAQVGNSVQMKQIEIQndKLKDAL 477
Cdd:COG1196 614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT---GGSRRELLAALLEAEAELE--ELAERL 688
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 478 IKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFN-MEER 556
Cdd:COG1196 689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEeLERE 768
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 557 IMQLEETIEDM--------EEARDLDEQLAEVQKQQvKDLMKEIEQLKIHIHELNGRIRD 608
Cdd:COG1196 769 LERLEREIEALgpvnllaiEEYEELEERYDFLSEQR-EDLEEARETLEEAIEEIDRETRE 827
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
318-528 |
4.46e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 4.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRvsfELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDENK- 396
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALER---RIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKe 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 397 -------------------VLLS--DHQDTMEMATIEKELAEERADSLQNDVLTLTEkLESMETELEILKEEMANgggaa 455
Cdd:COG4942 105 elaellralyrlgrqpplaLLLSpeDFLDAVRRLQYLKYLAPARREQAEELRADLAE-LAALRAELEAERAELEA----- 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 392900641 456 qvgnsvQMKQIEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAG 528
Cdd:COG4942 179 ------LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
63-303 |
4.55e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 44.84 E-value: 4.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 63 VKSSAVELEDASKRSGLKAPAASAIRKDSSVMSRSAGSKASP-GSSPGMSPAASSEKLTGRQTGMGPRSMSKLADPNEKK 141
Cdd:PRK07003 386 RAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPaAPAPPATADRGDDAADGDAPVPAKANARASADSRCDE 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 142 RSTTPQKARSP-------APPMTKKNSEST------SRMVREFSNLSQSSVASSRASASASKPRPQFTAPDPrrQSLAPP 208
Cdd:PRK07003 466 RDAQPPADSGSasapasdAPPDAAFEPAPRaaapsaATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTP--AAAAPA 543
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 209 KKASTTTAPVS-------KPSLSKPRQSLAPSKPAEVTPQKPVPAAqaseagdPPNELPLPTmtesgtelPKEsvlSRAK 281
Cdd:PRK07003 544 ARAGGAAAALDvlrnagmRVSSDRGARAAAAAKPAAAPAAAPKPAA-------PRVAVQVPT--------PRA---RAAT 605
|
250 260
....*....|....*....|..
gi 392900641 282 KIDDTGPAAPMSPLSTTAAARP 303
Cdd:PRK07003 606 GDAPPNGAARAEQAAESRGAPP 627
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
464-648 |
5.13e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 5.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 464 KQIEIQNDKLKDALIKLRDLNAQATLDRQKAvDEAERLKTENSELIRVAEnlkrqteiAESKIAGFQEQIDAAMGAEAMV 543
Cdd:COG4913 617 AELAELEEELAEAEERLEALEAELDALQERR-EALQRLAEYSWDEIDVAS--------AEREIAELEAELERLDASSDDL 687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 544 TQLtdknfnmEERIMQLEETIEDMEEARD-LDEQLAEVQKQQvKDLMKEIEQLKIHIHELNGRIR-------DEQKHAVD 615
Cdd:COG4913 688 AAL-------EEQLEELEAELEELEEELDeLKGEIGRLEKEL-EQAEEELDELQDRLEAAEDLARlelrallEERFAAAL 759
|
170 180 190
....*....|....*....|....*....|...
gi 392900641 616 LSQTILKFRErmaNLNSQIQDQKDQVLSLEEQL 648
Cdd:COG4913 760 GDAVERELRE---NLEERIDALRARLNRAEEEL 789
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
318-648 |
5.28e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 44.67 E-value: 5.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTE---KLEAARVKRKEDHTKVMELDRVSFELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDE 394
Cdd:PRK03918 274 EIEELEEKVKELKElkeKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKR 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 395 NKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANGGGaaqvgnsvQMKQIEIQNDKLK 474
Cdd:PRK03918 354 LEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA--------RIGELKKEIKELK 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 475 DALIKLRDLNAQATLDRQKAVDE--AERLKTENSELIRVAENLKRQTEIaESKIAGFQEQIDaamgaeamvtqltdKNFN 552
Cdd:PRK03918 426 KAIEELKKAKGKCPVCGRELTEEhrKELLEEYTAELKRIEKELKEIEEK-ERKLRKELRELE--------------KVLK 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 553 MEERIMQLEETIEDMEEardLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQtilkFRERMANLNS 632
Cdd:PRK03918 491 KESELIKLKELAEQLKE---LEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE----LKKKLAELEK 563
|
330
....*....|....*.
gi 392900641 633 QIQDQKDQVLSLEEQL 648
Cdd:PRK03918 564 KLDELEEELAELLKEL 579
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
318-651 |
5.28e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 44.67 E-value: 5.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRVSFELRSSEEVRSRLIQKITELEKQIG--DERIAKEQLQAWQDEN 395
Cdd:PRK03918 201 ELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRelEERIEELKKEIEELEE 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 396 KV------------------LLSDHQDtmEMATIEKELaeERADSLQNDVLTLTEKLESMETELEILKEEmangggaaqv 457
Cdd:PRK03918 281 KVkelkelkekaeeyiklseFYEEYLD--ELREIEKRL--SRLEEEINGIEERIKELEEKEERLEELKKK---------- 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 458 gnsvqMKQIEIQNDKLKDALIKLRDLnaqatldRQKaVDEAERLKTENSELirVAENLKRQTEIAESKIAGFQEQIDaam 537
Cdd:PRK03918 347 -----LKELEKRLEELEERHELYEEA-------KAK-KEELERLKKRLTGL--TPEKLEKELEELEKAKEEIEEEIS--- 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 538 gaeamvtQLTDKNFNMEERIMQLEETIEDMEEA--------RDLDEqlaEVQKQQVKDLMKEIEQLKIHIHELNGRIRDE 609
Cdd:PRK03918 409 -------KITARIGELKKEIKELKKAIEELKKAkgkcpvcgRELTE---EHRKELLEEYTAELKRIEKELKEIEEKERKL 478
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 392900641 610 QKHAVDLSQTILKFRERMANLnsqiqDQKDQVLSLEEQLHGH 651
Cdd:PRK03918 479 RKELRELEKVLKKESELIKLK-----ELAEQLKELEEKLKKY 515
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
499-693 |
5.84e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 5.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 499 ERLKTENSELIRVAenlKRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDLDEQLa 578
Cdd:COG4717 49 ERLEKEADELFKPQ---GRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL- 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 579 evqkQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTilkfRERMANLNSQIQDQKDQVLSLEEQLhghisvdndR 658
Cdd:COG4717 125 ----LQLLPLYQELEALEAELAELPERLEELEERLEELREL----EEELEELEAELAELQEELEELLEQL---------S 187
|
170 180 190
....*....|....*....|....*....|....*
gi 392900641 659 ASMVNQLQISANRnfAEDVERQVNAIEVEFARRQA 693
Cdd:COG4717 188 LATEEELQDLAEE--LEELQQRLAELEEELEEAQE 220
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
317-691 |
5.96e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 44.35 E-value: 5.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRVSFELRSSEEVRSRLIQKITELEKQIgderiakeQLQAwqDENK 396
Cdd:pfam05557 118 RQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRIKELEFEI--------QSQE--QDSE 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 397 VLLSDHQDTMEMATIEKELAEERAD-----SLQNDVLTLTEKLESMETELEILKEEMAngggaaqvgnsvQMKQIEIQND 471
Cdd:pfam05557 188 IVKNSKSELARIPELEKELERLREHnkhlnENIENKLLLKEEVEDLKRKLEREEKYRE------------EAATLELEKE 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 472 KLKDALIKLRDLNAQATLDRQKAVDEAERLKT-ENSELIRVAEN--LKRQTEIAESKIAGFQEQIDAAMgaeAMVTQLTD 548
Cdd:pfam05557 256 KLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQlQQREIVLKEENssLTSSARQLEKARRELEQELAQYL---KKIEDLNK 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 549 KNFNMEERIMQLEETIEDMEEARDL---------DEQLAEVQKQQVKDLMKEIEQL--KIHIHELNGRIRDEQkhavdLS 617
Cdd:pfam05557 333 KLKRHKALVRRLQRRVLLLTKERDGyrailesydKELTMSNYSPQLLERIEEAEDMtqKMQAHNEEMEAQLSV-----AE 407
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 392900641 618 QTILKFRERMANLNSQIQDQKDQVlSLEEQLHGHISVDNDRASmVNQLQISANRnfaedVERQVNAIEVEFARR 691
Cdd:pfam05557 408 EELGGYKQQAQTLERELQALRQQE-SLADPSYSKEEVDSLRRK-LETLELERQR-----LREQKNELEMELERR 474
|
|
| ClyA_Cry6Aa-like |
cd22656 |
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ... |
369-539 |
7.08e-04 |
|
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.
Pssm-ID: 439154 [Multi-domain] Cd Length: 309 Bit Score: 43.51 E-value: 7.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 369 QKITELEKQIGDERIAKEQLQAWQDENKVLlsdhqdTMEMATIEKelAEERADSLQNDVLTLTEKLESMETELEILKEEM 448
Cdd:cd22656 94 AEILELIDDLADATDDEELEEAKKTIKALL------DDLLKEAKK--YQDKAAKVVDKLTDFENQTEKDQTALETLEKAL 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 449 AngggaAQVGNSVQmkqiEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAG 528
Cdd:cd22656 166 K-----DLLTDEGG----AIARKEIKDLQKELEKLNEEYAAKLKAKIDELKALIADDEAKLAAALRLIADLTAADTDLDN 236
|
170
....*....|.
gi 392900641 529 FQEQIDAAMGA 539
Cdd:cd22656 237 LLALIGPAIPA 247
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
322-636 |
7.32e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 44.19 E-value: 7.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 322 LRNQVKELTEKLEAARVKRKEDHTKVMELDRVSFELRSSEEVRSRLIQKITELEKQI-GDERIAKEQLQAWQDENKVLLS 400
Cdd:TIGR00618 554 ERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLaCEQHALLRKLQPEQDLQDVRLH 633
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 401 DHQDTMEMATIEKELAEERADSLQNDV-----LTLTEKLESMETELEILKEEMANgggAAQVGNSVQMkqIEIQNDKLKD 475
Cdd:TIGR00618 634 LQQCSQELALKLTALHALQLTLTQERVrehalSIRVLPKELLASRQLALQKMQSE---KEQLTYWKEM--LAQCQTLLRE 708
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 476 ALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQ--TEIAESKIAGF----QEQIDAAMGAE--AMVTQLT 547
Cdd:TIGR00618 709 LETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQarTVLKARTEAHFnnneEVTAALQTGAElsHLAAEIQ 788
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 548 DKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQvkdLMKEIEQLKIHIHELN---GRIRDEQKHAVDLSQTILKFR 624
Cdd:TIGR00618 789 FFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCET---LVQEEEQFLSRLEEKSatlGEITHQLLKYEECSKQLAQLT 865
|
330
....*....|..
gi 392900641 625 ERMANLNSQIQD 636
Cdd:TIGR00618 866 QEQAKIIQLSDK 877
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
319-653 |
7.35e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.17 E-value: 7.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 319 IEYLRNQVKELTEKLEAARVKRKEDHtkvmeldrvsfELRSSEEVRSRLIQK-ITELEKQIGDERIAKEQLQ--AWQDEN 395
Cdd:COG3096 349 IERYQEDLEELTERLEEQEEVVEEAA-----------EQLAEAEARLEAAEEeVDSLKSQLADYQQALDVQQtrAIQYQQ 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 396 KV-LLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEI-------------LKEEMANGGGAAQVGnsv 461
Cdd:COG3096 418 AVqALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVadaarrqfekayeLVCKIAGEVERSQAW--- 494
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 462 qmkqieiqnDKLKDALIKLRDLNAQAtldrqkavDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMgaea 541
Cdd:COG3096 495 ---------QTARELLRRYRSQQALA--------QRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAE---- 553
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 542 mvtqltdknfNMEERIMQLEETIEDMEE-ARDLDEQLAEVQKQQvkdlmkeiEQLKIHIHELNGR-------------IR 607
Cdd:COG3096 554 ----------ELEELLAELEAQLEELEEqAAEAVEQRSELRQQL--------EQLRARIKELAARapawlaaqdalerLR 615
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 392900641 608 DEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLHGHIS 653
Cdd:COG3096 616 EQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALESQIE 661
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
97-584 |
7.38e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.96 E-value: 7.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 97 SAGSKASPGSSPGMSPAASSEKLTgrqTGMGPRSMSKLADPNEKKRSTTPQKARSPAPPMTKKNSES-----TSRMVREF 171
Cdd:pfam17380 82 SSYPVSAEVSPPGAPAAAPEEFVF---STIRPKSRKPKARTRGKKRKTTTTMIQTTTPMMVTTSSSAlemttTPKIVIFA 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 172 S-------NLSQSSVASSRASASASKPRPQFTAPDPRRQSLAPPKKASTTTAPvskpslsKPRQSLAPSKPAEVTPQKPV 244
Cdd:pfam17380 159 SkknasggNRSGEQRKQIQLIRRRRGNHSAFTRPGRPRTTTPMPVTHATRFVP-------GIQMSTVAPKEVQGMPHTLA 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 245 PAAQASEAGDPPNelplpTMTESGTELPKESVLSRAKKIDDTgpaAPMSPLSTTAAARPRTTSVSSSAQESSTEIEYLRN 324
Cdd:pfam17380 232 PYEKMERRKESFN-----LAEDVTTMTPEYTVRYNGQTMTEN---EFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQ 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 325 QVKELTE------KLEAARVKRK-----------EDHTKVME----LDRVSFELRSSEEVRSRLIQKITELEKQIGDERI 383
Cdd:pfam17380 304 EKEEKAReverrrKLEEAEKARQaemdrqaaiyaEQERMAMErereLERIRQEERKRELERIRQEEIAMEISRMRELERL 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 384 akeQLQAWQDENKVllsdhQDTMEMATIEKELAEERADSLQNDVLTL----TEKLESMETELEILKEEMANGGGAAQVGN 459
Cdd:pfam17380 384 ---QMERQQKNERV-----RQELEAARKVKILEEERQRKIQQQKVEMeqirAEQEEARQREVRRLEEERAREMERVRLEE 455
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 460 SVQMKQIEIQNDKLKDALIKLRDLNAQatlDRQKAVDEAERLKTENSEL-----IRVAENLKR---QTEIAESKIAGFQE 531
Cdd:pfam17380 456 QERQQQVERLRQQEEERKRKKLELEKE---KRDRKRAEEQRRKILEKELeerkqAMIEEERKRkllEKEMEERQKAIYEE 532
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 392900641 532 QIDAAMGAEAMVTQLTDKNFNMEERIMQLEET---IEDMEEARDLDEQLAEVQKQQ 584
Cdd:pfam17380 533 ERRREAEEERRKQQEMEERRRIQEQMRKATEErsrLEAMEREREMMRQIVESEKAR 588
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
80-305 |
7.39e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.01 E-value: 7.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 80 KAPAASAIRKDSSVMSRSAGSKASPGSSPGMSPAASSEKLTGRQTGMGPRSMSKLADPnekkrSTTPQKARSPAPPMTKK 159
Cdd:PHA03307 161 AVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASAS-----SPAPAPGRSAADDAGAS 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 160 NSESTSRMVREFSNlsqssvassRASASASKPRPQ-FTAPDPRRQSLAPpkKASTTTAPVSKPSLSKPRQSLAPSKPAEV 238
Cdd:PHA03307 236 SSDSSSSESSGCGW---------GPENECPLPRPApITLPTRIWEASGW--NGPSSRPGPASSSSSPRERSPSPSPSSPG 304
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 392900641 239 TPQKPVPA-AQASEAGDPPNELPLPTMTESGTE---LPKESVLSRAKKIDDTGPAAPMSPLSTTAAARPRT 305
Cdd:PHA03307 305 SGPAPSSPrASSSSSSSRESSSSSTSSSSESSRgaaVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAP 375
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
336-596 |
7.88e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 7.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 336 ARVKRKEDHTKVMELDRVSFELRSSEEVRsrliqKITELEKQIGDERIAkEQLQAWQDENKVLLSDHQDTMEMATIEKEL 415
Cdd:PTZ00121 1274 AEEARKADELKKAEEKKKADEAKKAEEKK-----KADEAKKKAEEAKKA-DEAKKKAEEAKKKADAAKKKAEEAKKAAEA 1347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 416 AEERADSLQNDVLTLTEKLESMETELEILKEEM-ANGGGAAQVGNSVQMKQIEIQNDKLKDALIKLRDLNAQATLDRQKA 494
Cdd:PTZ00121 1348 AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAdAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKA 1427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 495 --VDEAERLKtENSELIRVAENLKRQTEIAEsKIAGFQEQIDAAMGAEAMVTQLTDKNfNMEERIMQLEETIEDMEEARD 572
Cdd:PTZ00121 1428 eeKKKADEAK-KKAEEAKKADEAKKKAEEAK-KAEEAKKKAEEAKKADEAKKKAEEAK-KADEAKKKAEEAKKKADEAKK 1504
|
250 260
....*....|....*....|....
gi 392900641 573 LDEQLAEVQKQQVKDLMKEIEQLK 596
Cdd:PTZ00121 1505 AAEAKKKADEAKKAEEAKKADEAK 1528
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
453-709 |
8.84e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.21 E-value: 8.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 453 GAAQVGNSVQMKQIEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQ 532
Cdd:COG4942 12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 533 IdaamgaEAMVTQLTDKNFNMEERI-----MQLEETIEDMEEARDLDEQL--AEVQKQQVKDLMKEIEQLKIHIHELNGR 605
Cdd:COG4942 92 I------AELRAELEAQKEELAELLralyrLGRQPPLALLLSPEDFLDAVrrLQYLKYLAPARREQAEELRADLAELAAL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 606 IRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLHGHisvdndrasmvnQLQISANRNFAEDVERQVNAIE 685
Cdd:COG4942 166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAEL------------AAELAELQQEAEELEALIARLE 233
|
250 260
....*....|....*....|....
gi 392900641 686 VEFARRQagylKAFLPDNFSRVGG 709
Cdd:COG4942 234 AEAAAAA----ERTPAAGFAALKG 253
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
191-304 |
8.96e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 43.68 E-value: 8.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 191 PRPQFTAPDPRRQSLAPPKKAS------TTTAPVSKPSLSKPRQSLAPSKPAEVTPQKPVPAAQASEAGDPPNELPLPTM 264
Cdd:PRK07003 410 LAPKAAAAAAATRAEAPPAAPAppatadRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAA 489
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 392900641 265 TESGT-----------ELPKESVLSRAKKIDDTGPAAPMSPLSTT---AAARPR 304
Cdd:PRK07003 490 FEPAPraaapsaatpaAVPDARAPAAASREDAPAAAAPPAPEARPptpAAAAPA 543
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
465-649 |
1.17e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 43.08 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 465 QIEIQNDKLKDalikLRDLNAQATLDRQ----KAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGF-QEQIDAAMG- 538
Cdd:PHA02562 196 QIKTYNKNIEE----QRKKNGENIARKQnkydELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLnTAAAKIKSKi 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 539 -------------------------AEAMVTQLTDKNFNMEERIMQLEETIEDMEEARDldeQLAEVQKqQVKDLMKEIE 593
Cdd:PHA02562 272 eqfqkvikmyekggvcptctqqiseGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMD---EFNEQSK-KLLELKNKIS 347
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 392900641 594 QLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQLH 649
Cdd:PHA02562 348 TNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKY 403
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
367-625 |
1.44e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 42.97 E-value: 1.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 367 LIQKITELEKQIgdERIAKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERADSlqndVLTLTEKL--ESMETELEIL 444
Cdd:PLN02939 133 LVGMIQNAEKNI--LLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARI----KLAAQEKIhvEILEEQLEKL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 445 KEEMANGGGAAQVGNSVQMKQIEI---QNDKLKDALIKLR-DLNAQATLDRQKAVDEAER------LKTENSELIRVAEN 514
Cdd:PLN02939 207 RNELLIRGATEGLCVHSLSKELDVlkeENMLLKDDIQFLKaELIEVAETEERVFKLEKERslldasLRELESKFIVAQED 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 515 L----KRQTEIAESKIAGFQEQIDAAMGAEAMVTQLTDKNFNMEERIMQLEETIEDMEEARdLDEQLAEVQKQQVKDLMk 590
Cdd:PLN02939 287 VsklsPLQYDCWWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEANVSK-FSSYKVELLQQKLKLLE- 364
|
250 260 270
....*....|....*....|....*....|....*
gi 392900641 591 eiEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRE 625
Cdd:PLN02939 365 --ERLQASDHEIHSYIQLYQESIKEFQDTLSKLKE 397
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
412-692 |
1.50e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.11 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 412 EKELAEERADsLQNDVLTLTEKLESMETELEILKEEMANGGGAAQVgnsvQMKQIEIQNDKLKDALIKLRDLNAQATLDR 491
Cdd:TIGR00606 690 EAELQEFISD-LQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPG----RQSIIDLKEKEIPELRNKLQKVNRDIQRLK 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 492 QKAVDEAERLKTENSEL---------IRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAmVTQLTDKNFNMEERIMQLEE 562
Cdd:TIGR00606 765 NDIEEQETLLGTIMPEEesakvcltdVTIMERFQMELKDVERKIAQQAAKLQGSDLDRT-VQQVNQEKQEKQHELDTVVS 843
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 563 TIEDMEE-ARDLDEQLAEVQK----------------QQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRE 625
Cdd:TIGR00606 844 KIELNRKlIQDQQEQIQHLKSktnelkseklqigtnlQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQ 923
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 392900641 626 RMANL-------NSQIQDQKDQVLSLEEQLHGHisvdndRASMVNQLQISANRnFAEDVERQVNAIEVEFARRQ 692
Cdd:TIGR00606 924 EKEELissketsNKKAQDKVNDIKEKVKNIHGY------MKDIENKIQDGKDD-YLKQKETELNTVNAQLEECE 990
|
|
| DUF4045 |
pfam13254 |
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ... |
91-240 |
1.67e-03 |
|
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.
Pssm-ID: 433066 [Multi-domain] Cd Length: 415 Bit Score: 42.46 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 91 SSV-MSRSAGSKASPGSSPGMSPAASSEKLTGRQTGMGPRSMSKLADPNEKKRSTTPQKARSPAPPMTKKNSESTSRMVR 169
Cdd:pfam13254 190 ASVdLGRPNSFKEVTPVGLMRSPAPGGHSKSPSVSGISADSSPTKEEPSEEADTLSTDKEQSPAPTSASEPPPKTKELPK 269
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392900641 170 EFSnlsQSSVASSRASASASKPRPQFTA-PDPRRQSLAPPKKASTTTAPVSKPSLSKPRQSLAPsKPAEVTP 240
Cdd:pfam13254 270 DSE---EPAAPSKSAEASTEKKEPDTESsPETSSEKSAPSLLSPVSKASIDKPLSSPDRDPLSP-KPKPQSP 337
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
320-648 |
1.82e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 42.79 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 320 EYLRNQVKELTEKLEAarvKRKEDHTKVMELDRVsfelRSSEEVRSRLIQKI-TELEKqigdERIAKEQLQAWQD----E 394
Cdd:pfam05483 432 EELKGKEQELIFLLQA---REKEIHDLEIQLTAI----KTSEEHYLKEVEDLkTELEK----EKLKNIELTAHCDklllE 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 395 NKVLLSDHQD-TMEMATIEKEL-----AEERA----DSLQNDVLTLTEKLESMETELEILKEEMANGGGAAQVGNSVQMK 464
Cdd:pfam05483 501 NKELTQEASDmTLELKKHQEDIinckkQEERMlkqiENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEY 580
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 465 QIEIQNDKLKDALIKLRDLNAQATlDRQKAVDEaerLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAMGAEAMVT 544
Cdd:pfam05483 581 EVLKKEKQMKILENKCNNLKKQIE-NKNKNIEE---LHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEII 656
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 545 QLTDKnfNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQ----LKIHIHELNgRIRDEQKHAVDLSQTI 620
Cdd:pfam05483 657 DNYQK--EIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEmvalMEKHKHQYD-KIIEERDSELGLYKNK 733
|
330 340
....*....|....*....|....*....
gi 392900641 621 LKFRERM-ANLNSQIQDQKDQVLSLEEQL 648
Cdd:pfam05483 734 EQEQSSAkAALEIELSNIKAELLSLKKQL 762
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
320-648 |
1.92e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 42.80 E-value: 1.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 320 EYLRNQVKELTEK---LEAARVKRKEDHTKVMELDRvSFELRSSE--EVRSRLIQKITELE--KQIGDE-RIAKEQLQAW 391
Cdd:pfam15921 475 EMLRKVVEELTAKkmtLESSERTVSDLTASLQEKER-AIEATNAEitKLRSRVDLKLQELQhlKNEGDHlRNVQTECEAL 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 392 Q----DENKV-------------LLSDHQDT-----MEMATIEKELAEERADSLQNDVL-----TLTEKLESMETELEIL 444
Cdd:pfam15921 554 KlqmaEKDKVieilrqqienmtqLVGQHGRTagamqVEKAQLEKEINDRRLELQEFKILkdkkdAKIRELEARVSDLELE 633
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 445 KEEMANGGGAAQVGnsvqMKQIEIQNDKL----KDALIKLRDLNAQATLDRQKAVDEAERLKTENSEL---IRVAENLKR 517
Cdd:pfam15921 634 KVKLVNAGSERLRA----VKDIKQERDQLlnevKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLkmqLKSAQSELE 709
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 518 QTEIAESKIAGFQ-EQIDAAMGAEAMVTQLTDKNFNMEERIMQLEETIEDM--------EEARDLDEQLAEVQKQQVKdL 588
Cdd:pfam15921 710 QTRNTLKSMEGSDgHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNAnkekhflkEEKNKLSQELSTVATEKNK-M 788
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 589 MKEIEQLKIHIHELNGRIRDEQkhaVDLSQTILKFRERMANLnsQIQDQKDQVLSLEEQL 648
Cdd:pfam15921 789 AGELEVLRSQERRLKEKVANME---VALDKASLQFAECQDII--QRQEQESVRLKLQHTL 843
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
65-301 |
2.11e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.62 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 65 SSAVELEDASKRSGLKAPAASAirkdSSVMSRSAGSKASPGS-SPGMSPAASSekltgrqtgmGPRSMSKLADPnekkrS 143
Cdd:PHA03247 2716 VSATPLPPGPAAARQASPALPA----APAPPAVPAGPATPGGpARPARPPTTA----------GPPAPAPPAAP-----A 2776
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 144 TTPQKARSPAPPMTKKNSESTSRMVREFSNLSQSSVASSRASASASKPRP--------QFTAPDPRRQSLAPPKKASTTT 215
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGplppptsaQPTAPPPPPGPPPPSLPLGGSV 2856
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 216 AP---VSK--PSLSKPRQSLAPSKP-AEVTPQKPVPAAQASEA--GDPPNELPLPTMTESGTELPKESVLSRAKKIDDTG 287
Cdd:PHA03247 2857 APggdVRRrpPSRSPAAKPAAPARPpVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPP 2936
|
250
....*....|....*.
gi 392900641 288 --PAAPMSPLSTTAAA 301
Cdd:PHA03247 2937 prPQPPLAPTTDPAGA 2952
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
73-257 |
2.39e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 42.47 E-value: 2.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 73 ASKRSGLKAPAASAIRKDSSVMSRSAGSKASPGSSPGMSPAASSEKLTGRQTGMGPRSMSKLADPNEKKRSttPQKARSP 152
Cdd:PHA03307 768 LAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKRKSRSHTPDGGSESSGPARP--PGAAARP 845
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 153 APPMTKKNSESTSRMVRefsnlsqSSVASSRASASASKPRPQFTAPDPRRQSLAPPKKASTTTAPVSKPSLSKPRQSLAP 232
Cdd:PHA03307 846 PPARSSESSKSKPAAAG-------GRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPRVKLGPMPP 918
|
170 180 190
....*....|....*....|....*....|....
gi 392900641 233 SKPAEV---------TPQKPVPAAQASEAGDPPN 257
Cdd:PHA03307 919 GGPDPRggfrrvppgDLHTPAPSAAALAAYCPPE 952
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
317-446 |
2.47e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.35 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTE---KLEAARVKRKEDHTKVMEldrvsfELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQD 393
Cdd:TIGR02168 866 ELIEELESELEALLNeraSLEEALALLRSELEELSE------ELRELESKRSELRRELEELREKLAQLELRLEGLEVRID 939
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 392900641 394 ENK-VLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESM-------ETELEILKE 446
Cdd:TIGR02168 940 NLQeRLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaIEEYEELKE 1000
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
369-649 |
2.78e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 42.21 E-value: 2.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 369 QKITELEKQIGDE----RIAKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERAD--SLQNDVLTLTEKLESMETELE 442
Cdd:PRK11281 80 EETEQLKQQLAQApaklRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQlqNAQNDLAEYNSQLVSLQTQPE 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 443 ILKEEMANgggaaqvgNSVQMKQIEIQNDKLKDALIKLRD------------LNAQATLDRQ--------KAVDEAER-L 501
Cdd:PRK11281 160 RAQAALYA--------NSQRLQQIRNLLKGGKVGGKALRPsqrvllqaeqalLNAQNDLQRKslegntqlQDLLQKQRdY 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 502 KTENS-------ELIRVAENLKRQTEiAESKIAGFQEQIDAA-MGAEAMVTQLTDKNFNMEER-IMQLEETIEDMEEA-- 570
Cdd:PRK11281 232 LTARIqrlehqlQLLQEAINSKRLTL-SEKTVQEAQSQDEAArIQANPLVAQELEINLQLSQRlLKATEKLNTLTQQNlr 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 571 ------------RDLDEQLAEVQ----------KQQ--------VKDLMKEIEQLKIHIHELNgrirdeqkhavdlsqti 620
Cdd:PRK11281 311 vknwldrltqseRNIKEQISVLKgslllsrilyQQQqalpsadlIEGLADRIADLRLEQFEIN----------------- 373
|
330 340 350
....*....|....*....|....*....|
gi 392900641 621 lKFRERMANLNSQIQD-QKDQVLSLEEQLH 649
Cdd:PRK11281 374 -QQRDALFQPDAYIDKlEAGHKSEVTDEVR 402
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
76-297 |
3.06e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.06 E-value: 3.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 76 RSGLKAPAASAIRKDSSvMSRSAGSKASPGSSPGMSPAaSSEKLTGRQTGMGPRS----------------------MSK 133
Cdd:pfam03154 177 QSGAASPPSPPPPGTTQ-AATAGPTPSAPSVPPQGSPA-TSQPPNQTQSTAAPHTliqqtptlhpqrlpsphpplqpMTQ 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 134 LADPNEKKRSTTPQKA-RSPAPPMTKKNSESTSRM----------VREFSNLSQSSVASSRASASASKPRPQFTAPDPRR 202
Cdd:pfam03154 255 PPPPSQVSPQPLPQPSlHGQMPPMPHSLQTGPSHMqhpvppqpfpLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQL 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 203 QSLAPPKKASTTTAPVSKPSLskprqslapsKPAEVTPQKPVPAAQASEAgdpPNELPLPTMTESGTELPKESVLSrakk 282
Cdd:pfam03154 335 QSQQPPREQPLPPAPLSMPHI----------KPPPTTPIPQLPNPQSHKH---PPHLSGPSPFQMNSNLPPPPALK---- 397
|
250
....*....|....*
gi 392900641 283 iddtgpaaPMSPLST 297
Cdd:pfam03154 398 --------PLSSLST 404
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
384-686 |
3.40e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.43 E-value: 3.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 384 AKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANgggaaqvgNSVQM 463
Cdd:COG4372 11 ARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQ--------LEEEL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 464 KQIEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDaamgaeamv 543
Cdd:COG4372 83 EELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELK--------- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 544 tQLTDKNFNMEERIMQLEETIEDMEEARdLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKF 623
Cdd:COG4372 154 -ELEEQLESLQEELAALEQELQALSEAE-AEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKL 231
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 392900641 624 RERMANLNSQIQDQKDQVLSLEEQLHGHISVDNDRASMVNQLQISANRNFAEDVERQVNAIEV 686
Cdd:COG4372 232 GLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALE 294
|
|
| ClyA_Cry6Aa-like |
cd22656 |
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ... |
480-635 |
3.53e-03 |
|
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.
Pssm-ID: 439154 [Multi-domain] Cd Length: 309 Bit Score: 41.20 E-value: 3.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 480 LRDLNAQATLDRQKAVDEA-ERLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAmgaeamVTQLTDKNFNMEERIM 558
Cdd:cd22656 97 LELIDDLADATDDEELEEAkKTIKALLDDLLKEAKKYQDKAAKVVDKLTDFENQTEKD------QTALETLEKALKDLLT 170
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392900641 559 QlEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKihihELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQ 635
Cdd:cd22656 171 D-EGGAIARKEIKDLQKELEKLNEEYAAKLKAKIDELK----ALIADDEAKLAAALRLIADLTAADTDLDNLLALIG 242
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
318-648 |
3.65e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.97 E-value: 3.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRVSFELRS------------SEEVRSRLIQKIT-----------EL 374
Cdd:PRK03918 392 ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTaelkriekelkEI 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 375 EKQIGDERIAKEQLQAWQDENKVLLSDHQDTMEMATIEKELAEERAdslqndvltltEKLESMETELEILKEEMANGGGa 454
Cdd:PRK03918 472 EEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNL-----------EELEKKAEEYEKLKEKLIKLKG- 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 455 aqvgnsvqmkqiEIQNdkLKDALIKLRDLNAQATLdRQKAVDEAERlktENSELIRVAENLKRQT-EIAESKIAGFQEQI 533
Cdd:PRK03918 540 ------------EIKS--LKKELEKLEELKKKLAE-LEKKLDELEE---ELAELLKELEELGFESvEELEERLKELEPFY 601
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 534 DAAMGAEAMVTQLTDKnfnmEERIMQLEETIEDMEEarDLDEQLAEVQKqqvkdLMKEIEQL-KIHIHELNGRIRDEQkh 612
Cdd:PRK03918 602 NEYLELKDAEKELERE----EKELKKLEEELDKAFE--ELAETEKRLEE-----LRKELEELeKKYSEEEYEELREEY-- 668
|
330 340 350
....*....|....*....|....*....|....*.
gi 392900641 613 aVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQL 648
Cdd:PRK03918 669 -LELSRELAGLRAELEELEKRREEIKKTLEKLKEEL 703
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
98-304 |
3.67e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.70 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 98 AGSKASPGSSPGMSPAassEKLTGRQTGMGPRSmSKLADPnekkrstTPQKARSPAPPMTKKNSESTSRMVREFSNLSQS 177
Cdd:PHA03307 18 GEFFPRPPATPGDAAD---DLLSGSQGQLVSDS-AELAAV-------TVVAGAAACDRFEPPTGPPPGPGTEAPANESRS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 178 SVASSRASASASKPRPQFTAPDPRRQSLAPPKKASTT--TAPVSKPSLSKPRQSLAPSKPAEVTPQKPVPAAQASEAGDP 255
Cdd:PHA03307 87 TPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPasPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDA 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 392900641 256 PN----ELPLPTMTESGTEL--PKESVLSRAKKIDDTGPAAPMSPLSTTAAARPR 304
Cdd:PHA03307 167 ASsrqaALPLSSPEETARAPssPPAEPPPSTPPAAASPRPPRRSSPISASASSPA 221
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
60-297 |
3.74e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.70 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 60 GVFVKSSAvELEDAskrsglkAPAASAIRKDSSVMSRSAGSKASPGSSPGMSPAASSEKLTGRQTGMGPRSMSKLADPNE 139
Cdd:PHA03307 41 GQLVSDSA-ELAAV-------TVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPS 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 140 KKrSTTPQKARSPAPPmtkknsESTSRMVREfsnlsqssvassrasasASKPRPQFTAPDPRRQSLAPPKKASTTTAPVS 219
Cdd:PHA03307 113 SP-DPPPPTPPPASPP------PSPAPDLSE-----------------MLRPVGSPGPPPAASPPAAGASPAAVASDAAS 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 392900641 220 KPSLSKPRQSLAPSKPAEVTPQKPVPAAQASEAGDPPNELPLPTMTESGTelpkESVLSRAKKIDDTGPAAPMSPLST 297
Cdd:PHA03307 169 SRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASAS----SPAPAPGRSAADDAGASSSDSSSS 242
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
317-601 |
3.79e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 41.70 E-value: 3.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAArvkrkEDHTKVMELD----RVSFEL------RSSEEVRSRLIQKITELEKQIGDERIAKE 386
Cdd:pfam01576 692 QQVEEMKTQLEELEDELQAT-----EDAKLRLEVNmqalKAQFERdlqardEQGEEKRRQLVKQVRELEAELEDERKQRA 766
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 387 QLQAWQDENKVLLSDHQDTMEMATIEKELA-----------------------------------EERADSLQNDVLTLT 431
Cdd:pfam01576 767 QAVAAKKKLELDLKELEAQIDAANKGREEAvkqlkklqaqmkdlqreleearasrdeilaqskesEKKLKNLEAELLQLQ 846
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 432 EKLESME-------TELEILKEEMANG--GGAAQV-------GNSVQMKQ--------IEIQNDKLKDALIKLRDLNAQA 487
Cdd:pfam01576 847 EDLAASErarrqaqQERDELADEIASGasGKSALQdekrrleARIAQLEEeleeeqsnTELLNDRLRKSTLQVEQLTTEL 926
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 488 TLDR---QKAVDEAERLKTENSEL-IRVAE-----NLKRQTEIA--ESKIAGFQEQIDaamgAEAMVTQLTDKNFNMEER 556
Cdd:pfam01576 927 AAERstsQKSESARQQLERQNKELkAKLQEmegtvKSKFKSSIAalEAKIAQLEEQLE----QESRERQAANKLVRRTEK 1002
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 392900641 557 imQLEETIEDMEEARDLDEQLaevqKQQVKDLMKEIEQLKIHIHE 601
Cdd:pfam01576 1003 --KLKEVLLQVEDERRHADQY----KDQAEKGNSRMKQLKRQLEE 1041
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
407-596 |
3.90e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 3.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 407 EMATIEKELA--EERADSLQNDVLTLTEKLESMETELEILKEEmangggaaqvgnsvqMKQIEIQNDKLKDALIKLRDLN 484
Cdd:COG1579 11 DLQELDSELDrlEHRLKELPAELAELEDELAALEARLEAAKTE---------------LEDLEKEIKRLELEIEEVEARI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 485 AQATlDRQKAVDEAERLKTENSELirvaENLKRQTEIAESKIAGFQEQIDAamgAEAMVTQLtdknfnmEERIMQLEETI 564
Cdd:COG1579 76 KKYE-EQLGNVRNNKEYEALQKEI----ESLKRRISDLEDEILELMERIEE---LEEELAEL-------EAELAELEAEL 140
|
170 180 190
....*....|....*....|....*....|..
gi 392900641 565 EdmEEARDLDEQLAEVQKQQvKDLMKEIEQLK 596
Cdd:COG1579 141 E--EKKAELDEELAELEAEL-EELEAEREELA 169
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
318-664 |
4.13e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.96 E-value: 4.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRVSFELRSSEEVRSRL------------IQKITELEKQIGDERIAK 385
Cdd:TIGR01612 1359 KIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSKIestlddkdidecIKKIKELKNHILSEESNI 1438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 386 EQLQAWQDENKVLLSDHQDTMEMATIEKE-LAEERADSLQNDvltlteklesMETELEILKEemangggaaqvgNSVQMK 464
Cdd:TIGR01612 1439 DTYFKNADENNENVLLLFKNIEMADNKSQhILKIKKDNATND----------HDFNINELKE------------HIDKSK 1496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 465 QIEIQNDKLKDALIKLRDLNAQATLDRQKAVDEAERLKTENSelirvAENLKRQTEIAESKIAGFQEQIDAAMG-AEAMV 543
Cdd:TIGR01612 1497 GCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNK-----FAKTKKDSEIIIKEIKDAHKKFILEAEkSEQKI 1571
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 544 TQLTDKNFNMEERIMQLEET----IEDMEEARDLDEQLAEVQ--KQQVKDLMKEIEQLKIHIHELNGRIRD-EQKHAVDL 616
Cdd:TIGR01612 1572 KEIKKEKFRIEDDAAKNDKSnkaaIDIQLSLENFENKFLKISdiKKKINDCLKETESIEKKISSFSIDSQDtELKENGDN 1651
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 392900641 617 SQTILKFRERMANLNSQIQDQKDQVLSLEEQLHghiSVDNDrasmVNQ 664
Cdd:TIGR01612 1652 LNSLQEFLESLKDQKKNIEDKKKELDELDSEIE---KIEID----VDQ 1692
|
|
| DUF4045 |
pfam13254 |
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ... |
92-306 |
4.15e-03 |
|
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.
Pssm-ID: 433066 [Multi-domain] Cd Length: 415 Bit Score: 41.31 E-value: 4.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 92 SVMSRSAGSKASPGSSPGMSPAASSEKLTGRQTgmgpRSMSKLADPNEKKRSTTPQKARSPAPPMTKKNSeSTSRMVREF 171
Cdd:pfam13254 156 SALNRPESPKPKAQPSQPAQPAWMKELNKIRQS----RASVDLGRPNSFKEVTPVGLMRSPAPGGHSKSP-SVSGISADS 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 172 SNLSQSSVASSRASASASKPRPqftAPDPRRQSLAPPKKASTTTAPVSkpslskprqslAPSKPAEVTPQKPVPAAQASe 251
Cdd:pfam13254 231 SPTKEEPSEEADTLSTDKEQSP---APTSASEPPPKTKELPKDSEEPA-----------APSKSAEASTEKKEPDTESS- 295
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 392900641 252 agdppnelplPTMTESGTELPkesVLSRAKKIDDTGPAAPMSPLSTTAAARPRTT 306
Cdd:pfam13254 296 ----------PETSSEKSAPS---LLSPVSKASIDKPLSSPDRDPLSPKPKPQSP 337
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
99-262 |
4.19e-03 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 41.59 E-value: 4.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 99 GSKASPGSSPGMSPAASSEKLTGRQTGMGPRSMSKLADPNEKKRstTPQKARSPAPPMTKKNSESTSRMVREFSNLSQSS 178
Cdd:COG5180 223 HPRPEAASSPKVDPPSTSEARSRPATVDAQPEMRPPADAKERRR--AAIGDTPAAEPPGLPVLEAGSEPQSDAPEAETAR 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 179 VASSRASASASK-PRPQFTAP---DPRR----QSLAPPKKASTTTAPVSK-PSLSKPRQSLAPSKPAEVTPQKPVPAAQA 249
Cdd:COG5180 301 PIDVKGVASAPPaTRPVRPPGgarDPGTprpgQPTERPAGVPEAASDAGQpPSAYPPAEEAVPGKPLEQGAPRPGSSGGD 380
|
170
....*....|...
gi 392900641 250 SEAGDPPNELPLP 262
Cdd:COG5180 381 GAPFQPPNGAPQP 393
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
364-596 |
4.66e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.29 E-value: 4.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 364 RSRLIQKITELEKQIGDER-IAKEQLQAWQDENKvllsdhqdtmEMATIEKELAEeradslqndvltLTEKLESMETELE 442
Cdd:COG4717 48 LERLEKEADELFKPQGRKPeLNLKELKELEEELK----------EAEEKEEEYAE------------LQEELEELEEELE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 443 ILKEEmangggaaqvgnsvqMKQIEIQNDKLKDALIKLRDLNAQATLDRQKA--VDEAERLKTENSELirvaENLKRQTE 520
Cdd:COG4717 106 ELEAE---------------LEELREELEKLEKLLQLLPLYQELEALEAELAelPERLEELEERLEEL----RELEEELE 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 392900641 521 IAESKIAGFQEQIDAAmgaeamvtqLTDKNFNMEERIMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLK 596
Cdd:COG4717 167 ELEAELAELQEELEEL---------LEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE 233
|
|
| CENP-Q |
pfam13094 |
CENP-Q, a CENPA-CAD centromere complex subunit; CENP-Q is one of the components that assembles ... |
544-663 |
5.01e-03 |
|
CENP-Q, a CENPA-CAD centromere complex subunit; CENP-Q is one of the components that assembles onto the CENPA-nucleosome distal (CAD) centromere. The centromere, which is the basic element of chromosome inheritance, is epigenetically determined in mammals. CENP-A, the centromere-specific histone H3 variant, assembles an array of nucleosomes and it is this that seems to be the prime candidate for specifying centromere identity. CENPA nucleosomes directly recruit a proximal CENPA-nucleosome-associated complex (NAC) comprised of CENP-M, CENP-N and CENP-T, CENP-U(50), CENP-C and CENP-H. Assembly of the CENPA NAC at centromeres is dependent on CENP-M, CENP-N and CENP-T. Additionally, there are seven other subunits which make up the CENPA-nucleosome distal (CAD) centromere, CENP-K, CENP-L, CENP-O, CENP-P, CENP-Q, CENP-R and CENP-S, also assembling on the CENP-A NAC. Fta7 is the equivalent component of the fission yeast Sim4 complex.
Pssm-ID: 432970 [Multi-domain] Cd Length: 159 Bit Score: 39.19 E-value: 5.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 544 TQLTDKNfNMEER--------IMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVD 615
Cdd:pfam13094 22 EKLLDRN-KALEAqlsaelhsLELLEEEIEKEEALLESDEEYLEELEKNAKAEARERKEKLKKEHPLLQEDDSGVLSLPE 100
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 392900641 616 LSQTILKFRERMANLNSQIQdqkDQVLSLEEQLHGHI-SVDNDRASMVN 663
Cdd:pfam13094 101 LSSDLGLGDTDFSLFDPTLD---EELLPLLEQLQKHLeSMQGNLAQLEG 146
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
331-664 |
5.87e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 41.04 E-value: 5.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 331 EKLEAARVKRKEDHTKVMELDRVSFELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDENKVLLSDHQDtmemaT 410
Cdd:PRK01156 332 SVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPD-----A 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 411 IEKELAEERADSLQ--NDVLTLTEKLESMETELEILKEEMA--NGGGAAQV-----GNSVQMKQIEIQNDKLKDALIKLR 481
Cdd:PRK01156 407 IKKELNEINVKLQDisSKVSSLNQRIRALRENLDELSRNMEmlNGQSVCPVcgttlGEEKSNHIINHYNEKKSRLEEKIR 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 482 DLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQI----DAAMGAEAMVTQ--------LTDK 549
Cdd:PRK01156 487 EIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKInelkDKHDKYEEIKNRykslkledLDSK 566
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 550 NF-----------------------------NMEERIMQLEETIEDM------------EEARDLDEQLAEVQ--KQQVK 586
Cdd:PRK01156 567 RTswlnalavislidietnrsrsneikkqlnDLESRLQEIEIGFPDDksyidksireieNEANNLNNKYNEIQenKILIE 646
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 587 DLMKEIEQLKIHIHELNGRIRDEQkhavDLSQTILKFRERMANLNSQIQDQKDQVLSLE---EQLHGHISVDNDRASMVN 663
Cdd:PRK01156 647 KLRGKIDNYKKQIAEIDSIIPDLK----EITSRINDIEDNLKKSRKALDDAKANRARLEstiEILRTRINELSDRINDIN 722
|
.
gi 392900641 664 Q 664
Cdd:PRK01156 723 E 723
|
|
| Laminin_II |
pfam06009 |
Laminin Domain II; It has been suggested that the domains I and II from laminin A, B1 and B2 ... |
568-654 |
6.02e-03 |
|
Laminin Domain II; It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Pssm-ID: 368703 [Multi-domain] Cd Length: 138 Bit Score: 38.62 E-value: 6.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 568 EEARDLDEQLAEVQkQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQ 647
Cdd:pfam06009 3 ELAREANETAKEVL-EQLAPLSQNLENTSEKLSGINRSLEETNELVNDANKALDDAGRSVKKLEELAPDLLDKLKPLKQL 81
|
....*..
gi 392900641 648 LHGHISV 654
Cdd:pfam06009 82 EVNSSSL 88
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
333-682 |
6.09e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 40.96 E-value: 6.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 333 LEAARVKRKEDHTKVMELDRvsfELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDENKVLLSDHQDTMEMATIE 412
Cdd:pfam10174 41 LKKERALRKEEAARISVLKE---QYRVTQEENQHLQLTIQALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEEN 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 413 KELAEERADSLQNDVLTLTEKLESMETELEILKEEManGGGAAQVGNSVQMkqieIQNDKLKDALIKLRDLNAQATLDRQ 492
Cdd:pfam10174 118 FRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTL--GARDESIKKLLEM----LQSKGLPKKSGEEDWERTRRIAEAE 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 493 KAVDEAE-RLKTENSELIRVAENLKRQTEIAE--SKIAGFQEQIDAAmgaeamvtqltdknfnmEERIMQLEETIEDMEE 569
Cdd:pfam10174 192 MQLGHLEvLLDQKEKENIHLREELHRRNQLQPdpAKTKALQTVIEMK-----------------DTKISSLERNIRDLED 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 570 ARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNGRIrDEQKHAVDLSQT-ILKFRERMANLNSQIQDQKDQVLSLEEQL 648
Cdd:pfam10174 255 EVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKI-DQLKQELSKKESeLLALQTKLETLTNQNSDCKQHIEVLKESL 333
|
330 340 350
....*....|....*....|....*....|....
gi 392900641 649 hghiSVDNDRASMVnQLQISANRNFAEDVERQVN 682
Cdd:pfam10174 334 ----TAKEQRAAIL-QTEVDALRLRLEEKESFLN 362
|
|
| PspA_IM30 |
pfam04012 |
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ... |
482-597 |
6.09e-03 |
|
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.
Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 39.66 E-value: 6.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 482 DLNAQATLDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKIAGFQEQID-------AAMGAEAMVTQL----TDKN 550
Cdd:pfam04012 83 ELAREALAEKKSLEKQAEALETQLAQQRSAVEQLRKQLAALETKIQQLKAKKNllkarlkAAKAQEAVQTSLgslsTSSA 162
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 392900641 551 FNMEERImqlEETIEDMEEARDLDEQLAevqkqQVKDLMKEIEQLKI 597
Cdd:pfam04012 163 TDSFERI---EEKIEEREARADAAAELA-----SAVDLDAKLEQAGI 201
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
318-570 |
6.80e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 40.96 E-value: 6.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 318 EIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRVSFELRSS-EEVRSRLIQKITELEKQIGDERIAKEQLQAWQDENK 396
Cdd:pfam10174 469 ELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSgLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEE 548
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 397 VLLSDHQDTMEMATIEKELAEERADS--LQNDVLTLTEKLESMETELEILKEEMANgggaAQVGNSVQMKQIEIQNDKLK 474
Cdd:pfam10174 549 AVRTNPEINDRIRLLEQEVARYKEESgkAQAEVERLLGILREVENEKNDKDKKIAE----LESLTLRQMKEQNKKVANIK 624
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 475 DALIKLRDLNAQATLDRQKAVDEAER--LKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAamgAEAMVTQLTdknfn 552
Cdd:pfam10174 625 HGQQEMKKKGAQLLEEARRREDNLADnsQQLQLEELMGALEKTRQELDATKARLSSTQQSLAE---KDGHLTNLR----- 696
|
250
....*....|....*...
gi 392900641 553 mEERIMQLEETIEDMEEA 570
Cdd:pfam10174 697 -AERRKQLEEILEMKQEA 713
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
317-503 |
6.94e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 40.79 E-value: 6.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRvsfELRSSEEVRSRLiQKITELEKQIGDERIAKEQLQAWQDENK 396
Cdd:PRK02224 551 AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKE---RIESLERIRTLL-AAIADAEDEIERLREKREALAELNDERR 626
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 397 VLLSDHQDtmEMATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEMANgggaaqVGNSVQMKQIEIQN-DKLKD 475
Cdd:PRK02224 627 ERLAEKRE--RKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDD------LQAEIGAVENELEElEELRE 698
|
170 180
....*....|....*....|....*....
gi 392900641 476 ALIKLrdlnaQATLDRQKAV-DEAERLKT 503
Cdd:PRK02224 699 RREAL-----ENRVEALEALyDEAEELES 722
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
500-648 |
7.06e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.91 E-value: 7.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 500 RLKTENSELIRVAENLKRQTEIAESKIAGFQEQIDAAmgaEAMVTQLtdknfnmEERIMQLEETIEDMEEARD-LDEQLA 578
Cdd:COG1579 14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAA---KTELEDL-------EKEIKRLELEIEEVEARIKkYEEQLG 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 392900641 579 EVQKQ-QVKDLMKEIEQLKihihelnGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQL 648
Cdd:COG1579 84 NVRNNkEYEALQKEIESLK-------RRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL 147
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
409-647 |
7.46e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.20 E-value: 7.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 409 ATIEKELAEERADSLQNDVLTLTEKLESMETELEILKEEmangggaaqvgnsvqmkqIEIQNDKLKDALIKLRDLNAQAT 488
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEE------------------YNELQAELEALQAEIDKLQAEIA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 489 LDRQKAVDEAERLKTENSELIRVAENLKRQTEIAESKiaGFQEQIDAAmgaeAMVTQLTDKNFNMeerimqLEETIEDME 568
Cdd:COG3883 76 EAEAEIEERREELGERARALYRSGGSVSYLDVLLGSE--SFSDFLDRL----SALSKIADADADL------LEELKADKA 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 392900641 569 EARDLDEQLAEvQKQQVKDLMKEIEQLKihiHELNGRIRDEQKHAVDLSQTILKFRERMANLNSQIQDQKDQVLSLEEQ 647
Cdd:COG3883 144 ELEAKKAELEA-KLAELEALKAELEAAK---AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAA 218
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
411-692 |
7.69e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 40.86 E-value: 7.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 411 IEKELA--EERADSLQNDVLTLTEKLESMETELEILKEEMANGGGAAQVGNSVQMKQIEIQNDKLKDALIKLRDLNAQAT 488
Cdd:pfam05483 192 IEKMILafEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKAN 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 489 LDRQKAVDEAERLKTENSE---LIRVAENLKRQTEIAESKIAGFQEQIDAAMgaeAMVTQLTD-KNFNMEER-------- 556
Cdd:pfam05483 272 QLEEKTKLQDENLKELIEKkdhLTKELEDIKMSLQRSMSTQKALEEDLQIAT---KTICQLTEeKEAQMEELnkakaahs 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 557 --IMQLEETIEDMEEARDLDEQLAEVQKQQVKDLMKEIEQLKIHIHELNgRIRDEQKHAVDLSQTILKFRERMANLNSQI 634
Cdd:pfam05483 349 fvVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMT-KFKNNKEVELEELKKILAEDEKLLDEKKQF 427
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 392900641 635 QDQKDQVLSLEEQLHGHISVDNDRASMVnQLQISANRNFAEDVERQVNAIEVEFARRQ 692
Cdd:pfam05483 428 EKIAEELKGKEQELIFLLQAREKEIHDL-EIQLTAIKTSEEHYLKEVEDLKTELEKEK 484
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
554-685 |
8.20e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.20 E-value: 8.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 554 EERIMQLEETIEDME-EARDLDEQLAEVQkQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKFRERMANLNS 632
Cdd:COG3883 15 DPQIQAKQKELSELQaELEAAQAELDALQ-AELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR 93
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 392900641 633 QIQdQKDQVLSLEEQLHGHISVDN--DRASMVNQLqISANRNFAEDVERQVNAIE 685
Cdd:COG3883 94 ALY-RSGGSVSYLDVLLGSESFSDflDRLSALSKI-ADADADLLEELKADKAELE 146
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
317-685 |
8.55e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.82 E-value: 8.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAARVKRKEDHTKVMELDRvsfELRSSEEVRSRLIQKITELEKQIGDERIAKEQLQAWQDENK 396
Cdd:TIGR02169 364 EELEDLRAELEEVDKEFAETRDELKDYREKLEKLKR---EINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELE 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 397 VLLSDHQDtmEMATIEKELAEERAD--SLQNDVLTLTEKLESMETELEILKEEMANggGAAQVGNSVQMKQIEIQNDKLK 474
Cdd:TIGR02169 441 EEKEDKAL--EIKKQEWKLEQLAADlsKYEQELYDLKEEYDRVEKELSKLQRELAE--AEAQARASEERVRGGRAVEEVL 516
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 475 DA-----------LIKLRD-------------LNAQATLDRQKAVDEAERLKTENS------ELIRVAENLKRQTEIAES 524
Cdd:TIGR02169 517 KAsiqgvhgtvaqLGSVGEryataievaagnrLNNVVVEDDAVAKEAIELLKRRKAgratflPLNKMRDERRDLSILSED 596
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 525 KIAGFQ------------------------EQIDAA---MGAEAMVT---QLTDKNFNM-----------------EERI 557
Cdd:TIGR02169 597 GVIGFAvdlvefdpkyepafkyvfgdtlvvEDIEAArrlMGKYRMVTlegELFEKSGAMtggsraprggilfsrsePAEL 676
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 558 MQLEETIEDMEEARD------------LDEQLAEVQ--KQQVKDLMKEIEQLKIHIHELNGRIRDEQKHAVDLSQTILKF 623
Cdd:TIGR02169 677 QRLRERLEGLKRELSslqselrrienrLDELSQELSdaSRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 392900641 624 RERMANLNSQIQDQKDQVLSLEEQLhghisvdNDRASMVNQLQISANRNFAEDVERQVNAIE 685
Cdd:TIGR02169 757 KSELKELEARIEELEEDLHKLEEAL-------NDLEARLSHSRIPEIQAELSKLEEEVSRIE 811
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
65-304 |
8.77e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 40.54 E-value: 8.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 65 SSAVELEDASKRsglKAPAASAIRKDSSVMSRSAGSKASPGSSPGMSPAASSEKLtgrqtGMGPRSMSKLADPNEKKRST 144
Cdd:PHA03307 73 PGPGTEAPANES---RSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPA-----SPPPSPAPDLSEMLRPVGSP 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 145 TPQ-KARSPAPPMTKKNSESTSRMVREFSNLSQSSVASSRASASASKPRPqfTAPDPRRQSLAPPKKASTTTAPVSKPSL 223
Cdd:PHA03307 145 GPPpAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPP--PSTPPAAASPRPPRRSSPISASASSPAP 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 224 SKPRQSLAPSKPAEVTPQKPVPA----AQASEAGDP---PNELPLPTMTESGTELP---KESVLSRAKKIDDTGPAAPMS 293
Cdd:PHA03307 223 APGRSAADDAGASSSDSSSSESSgcgwGPENECPLPrpaPITLPTRIWEASGWNGPssrPGPASSSSSPRERSPSPSPSS 302
|
250
....*....|.
gi 392900641 294 PLSTTAAARPR 304
Cdd:PHA03307 303 PGSGPAPSSPR 313
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
1050-1288 |
8.85e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 40.58 E-value: 8.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 1050 EGLRWQMEKKDNEMLELRKQMKARIEDVSNYKLRLDMAESRLNSTDKAEgDKVKHLEEKINQM----VADHRRKQIEYDE 1125
Cdd:pfam10174 404 ENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERII-ERLKEQREREDRErleeLESLKKENKDLKE 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 1126 SMDALQREMKEVESDNLELKQRANKISKEALWKN--IQSMEtrssgspsVPMSTSIDEGGAsrgevvfLENQLNKQTN-- 1201
Cdd:pfam10174 483 KVSALQPELTEKESSLIDLKEHASSLASSGLKKDskLKSLE--------IAVEQKKEECSK-------LENQLKKAHNae 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 1202 --ARKRAEL--EVRKLKGELA---QAGSKRFSAVPGLISgpITLESQTRQDLLLKLIDNLHDESLRLRREEVNHQAYVPS 1274
Cdd:pfam10174 548 eaVRTNPEIndRIRLLEQEVArykEESGKAQAEVERLLG--ILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKH 625
|
250
....*....|....
gi 392900641 1275 NPKISTEKMVEEME 1288
Cdd:pfam10174 626 GQQEMKKKGAQLLE 639
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
192-300 |
9.52e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 40.69 E-value: 9.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 192 RPQFTAPD-----------PRRQSLAPPKKAST--TTAPVSKPSLSKPRQSLAPSKPAEVtpqkPVPAAQASEAGDPPN- 257
Cdd:PHA03247 356 RPTWTPPSsledlsagrhhPKRASLPTRKRRSArhAATPFARGPGGDDQTRPAAPVPASV----PTPAPTPVPASAPPPp 431
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 392900641 258 ELPLPTMTESGTELPKeSVLSRAKKIDDTGPAAPMSPLSTTAA 300
Cdd:PHA03247 432 ATPLPSAEPGSDDGPA-PPPERQPPAPATEPAPDDPDDATRKA 473
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
317-687 |
9.83e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 40.49 E-value: 9.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 317 TEIEYLRNQVKELTEKLEAArvkrKEDHTKVMEL------DRVSfELRSSEEV------------RSRLIQKITELE--- 375
Cdd:pfam15921 231 TEISYLKGRIFPVEDQLEAL----KSESQNKIELllqqhqDRIE-QLISEHEVeitgltekassaRSQANSIQSQLEiiq 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 376 -----------KQIGDERIAKEQLQAWQDENKVLLSDHQDTME--MATIEKELAEERAD---------SLQNDVLTLTEK 433
Cdd:pfam15921 306 eqarnqnsmymRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqLVLANSELTEARTErdqfsqesgNLDDQLQKLLAD 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 434 LESMETELEILKEE--------MANGGGAAQVGNSVQMKQIEIQNdklKDALIKLRDLNAQATLDRQKAVdeaerLKTEN 505
Cdd:pfam15921 386 LHKREKELSLEKEQnkrlwdrdTGNSITIDHLRRELDDRNMEVQR---LEALLKAMKSECQGQMERQMAA-----IQGKN 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 506 SELIRVAeNLKRQTEIAESKIAGFQEQIDA-AMGAEAMVTQLTDKNFNMEERIMQLEETIEDMEEARD-LDEQLAEVQ-- 581
Cdd:pfam15921 458 ESLEKVS-SLTAQLESTKEMLRKVVEELTAkKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSrVDLKLQELQhl 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392900641 582 ---KQQVKDLMKEIEQLKIHIHELNGRIRdeqkhavDLSQTIlkfrERMANLNSQIQDQKDQVLSLEEQLHGHIsvdNDR 658
Cdd:pfam15921 537 kneGDHLRNVQTECEALKLQMAEKDKVIE-------ILRQQI----ENMTQLVGQHGRTAGAMQVEKAQLEKEI---NDR 602
|
410 420 430
....*....|....*....|....*....|.
gi 392900641 659 ASMVNQLQISANRNFAE--DVERQVNAIEVE 687
Cdd:pfam15921 603 RLELQEFKILKDKKDAKirELEARVSDLELE 633
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